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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:CXADR-APP

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: CXADR-APP
FusionPDB ID: 20798
FusionGDB2.0 ID: 20798
HgeneTgene
Gene symbol

CXADR

APP

Gene ID

1525

351

Gene nameCXADR Ig-like cell adhesion moleculeamyloid beta precursor protein
SynonymsCAR|CAR4/6|HCARAAA|ABETA|ABPP|AD1|APPI|CTFgamma|CVAP|PN-II|PN2|preA4
Cytomap

21q21.1

21q21.3

Type of geneprotein-codingprotein-coding
Descriptioncoxsackievirus and adenovirus receptor46 kD coxsackievirus and adenovirus receptor (CAR) proteinCVB3-binding proteinHCVADRcoxsackie virus and adenovirus receptorcoxsackievirus B-adenovirus receptoramyloid-beta precursor proteinalzheimer disease amyloid proteinamyloid beta (A4) precursor proteinamyloid beta A4 proteinamyloid precursor proteinbeta-amyloid peptidebeta-amyloid peptide(1-40)beta-amyloid peptide(1-42)beta-amyloid precursor protei
Modification date2020031320200329
UniProtAcc

P78310

Q8NEU8

Ensembl transtripts involved in fusion geneENST idsENST00000284878, ENST00000306618, 
ENST00000356275, ENST00000400165, 
ENST00000400166, ENST00000400169, 
ENST00000474136, ENST00000346798, 
ENST00000348990, ENST00000354192, 
ENST00000357903, ENST00000358918, 
ENST00000359726, ENST00000439274, 
ENST00000440126, ENST00000448388, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 11 X 6=85825 X 18 X 10=4500
# samples 1327
** MAII scorelog2(13/858*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/4500*10)=-4.05889368905357
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: CXADR [Title/Abstract] AND APP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)CXADR(18885490)-APP(27425664), # samples:5
Anticipated loss of major functional domain due to fusion event.CXADR-APP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CXADR-APP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CXADR-APP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CXADR-APP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCXADR

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

12869515|15800062

HgeneCXADR

GO:0031532

actin cytoskeleton reorganization

17675666

TgeneAPP

GO:0001934

positive regulation of protein phosphorylation

11404397

TgeneAPP

GO:0008285

negative regulation of cell proliferation

22944668

TgeneAPP

GO:1905606

regulation of presynapse assembly

19726636


check buttonFusion gene breakpoints across CXADR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across APP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-CH-5792-01ACXADRchr21

18885489

+APPchr21

27425663

-
ChimerDB4PRADTCGA-CH-5792-01ACXADRchr21

18885490

-APPchr21

27425664

-
ChimerDB4PRADTCGA-CH-5792-01ACXADRchr21

18885490

+APPchr21

27425664

-
ChimerDB4PRADTCGA-CH-5792CXADRchr21

18885490

+APPchr21

27425664

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000284878CXADRchr2118885490+ENST00000346798APPchr2127425664-38697915172748743
ENST00000284878CXADRchr2118885490+ENST00000354192APPchr2127425664-36447915172523668
ENST00000284878CXADRchr2118885490+ENST00000348990APPchr2127425664-36447915172523668
ENST00000284878CXADRchr2118885490+ENST00000357903APPchr2127425664-38127915172691724
ENST00000284878CXADRchr2118885490+ENST00000358918APPchr2127425664-38147915172694725
ENST00000284878CXADRchr2118885490+ENST00000359726APPchr2127425664-37007915172580687
ENST00000284878CXADRchr2118885490+ENST00000448388APPchr2127425664-28677915172523668
ENST00000284878CXADRchr2118885490+ENST00000440126APPchr2127425664-30317915172691724
ENST00000284878CXADRchr2118885490+ENST00000439274APPchr2127425664-30877915172748743
ENST00000400166CXADRchr2118885490+ENST00000346798APPchr2127425664-3205127842084666
ENST00000400166CXADRchr2118885490+ENST00000354192APPchr2127425664-2980127841859591
ENST00000400166CXADRchr2118885490+ENST00000348990APPchr2127425664-2980127841859591
ENST00000400166CXADRchr2118885490+ENST00000357903APPchr2127425664-3148127842027647
ENST00000400166CXADRchr2118885490+ENST00000358918APPchr2127425664-3150127842030648
ENST00000400166CXADRchr2118885490+ENST00000359726APPchr2127425664-3036127841916610
ENST00000400166CXADRchr2118885490+ENST00000448388APPchr2127425664-2203127841859591
ENST00000400166CXADRchr2118885490+ENST00000440126APPchr2127425664-2367127842027647
ENST00000400166CXADRchr2118885490+ENST00000439274APPchr2127425664-2423127842084666
ENST00000356275CXADRchr2118885490+ENST00000346798APPchr2127425664-31214302000666
ENST00000356275CXADRchr2118885490+ENST00000354192APPchr2127425664-28964301775591
ENST00000356275CXADRchr2118885490+ENST00000348990APPchr2127425664-28964301775591
ENST00000356275CXADRchr2118885490+ENST00000357903APPchr2127425664-30644301943647
ENST00000356275CXADRchr2118885490+ENST00000358918APPchr2127425664-30664301946648
ENST00000356275CXADRchr2118885490+ENST00000359726APPchr2127425664-29524301832610
ENST00000356275CXADRchr2118885490+ENST00000448388APPchr2127425664-21194301775591
ENST00000356275CXADRchr2118885490+ENST00000440126APPchr2127425664-22834301943647
ENST00000356275CXADRchr2118885490+ENST00000439274APPchr2127425664-23394302000666
ENST00000400165CXADRchr2118885490+ENST00000346798APPchr2127425664-31214302000666
ENST00000400165CXADRchr2118885490+ENST00000354192APPchr2127425664-28964301775591
ENST00000400165CXADRchr2118885490+ENST00000348990APPchr2127425664-28964301775591
ENST00000400165CXADRchr2118885490+ENST00000357903APPchr2127425664-30644301943647
ENST00000400165CXADRchr2118885490+ENST00000358918APPchr2127425664-30664301946648
ENST00000400165CXADRchr2118885490+ENST00000359726APPchr2127425664-29524301832610
ENST00000400165CXADRchr2118885490+ENST00000448388APPchr2127425664-21194301775591
ENST00000400165CXADRchr2118885490+ENST00000440126APPchr2127425664-22834301943647
ENST00000400165CXADRchr2118885490+ENST00000439274APPchr2127425664-23394302000666
ENST00000306618CXADRchr2118885490+ENST00000346798APPchr2127425664-31214302000666
ENST00000306618CXADRchr2118885490+ENST00000354192APPchr2127425664-28964301775591
ENST00000306618CXADRchr2118885490+ENST00000348990APPchr2127425664-28964301775591
ENST00000306618CXADRchr2118885490+ENST00000357903APPchr2127425664-30644301943647
ENST00000306618CXADRchr2118885490+ENST00000358918APPchr2127425664-30664301946648
ENST00000306618CXADRchr2118885490+ENST00000359726APPchr2127425664-29524301832610
ENST00000306618CXADRchr2118885490+ENST00000448388APPchr2127425664-21194301775591
ENST00000306618CXADRchr2118885490+ENST00000440126APPchr2127425664-22834301943647
ENST00000306618CXADRchr2118885490+ENST00000439274APPchr2127425664-23394302000666
ENST00000400169CXADRchr2118885490+ENST00000346798APPchr2127425664-31214302000666
ENST00000400169CXADRchr2118885490+ENST00000354192APPchr2127425664-28964301775591
ENST00000400169CXADRchr2118885490+ENST00000348990APPchr2127425664-28964301775591
ENST00000400169CXADRchr2118885490+ENST00000357903APPchr2127425664-30644301943647
ENST00000400169CXADRchr2118885490+ENST00000358918APPchr2127425664-30664301946648
ENST00000400169CXADRchr2118885490+ENST00000359726APPchr2127425664-29524301832610
ENST00000400169CXADRchr2118885490+ENST00000448388APPchr2127425664-21194301775591
ENST00000400169CXADRchr2118885490+ENST00000440126APPchr2127425664-22834301943647
ENST00000400169CXADRchr2118885490+ENST00000439274APPchr2127425664-23394302000666
ENST00000284878CXADRchr2118885489+ENST00000346798APPchr2127425663-38697915172748743
ENST00000284878CXADRchr2118885489+ENST00000354192APPchr2127425663-36447915172523668
ENST00000284878CXADRchr2118885489+ENST00000348990APPchr2127425663-36447915172523668
ENST00000284878CXADRchr2118885489+ENST00000357903APPchr2127425663-38127915172691724
ENST00000284878CXADRchr2118885489+ENST00000358918APPchr2127425663-38147915172694725
ENST00000284878CXADRchr2118885489+ENST00000359726APPchr2127425663-37007915172580687
ENST00000284878CXADRchr2118885489+ENST00000448388APPchr2127425663-28677915172523668
ENST00000284878CXADRchr2118885489+ENST00000440126APPchr2127425663-30317915172691724
ENST00000284878CXADRchr2118885489+ENST00000439274APPchr2127425663-30877915172748743
ENST00000400166CXADRchr2118885489+ENST00000346798APPchr2127425663-3205127842084666
ENST00000400166CXADRchr2118885489+ENST00000354192APPchr2127425663-2980127841859591
ENST00000400166CXADRchr2118885489+ENST00000348990APPchr2127425663-2980127841859591
ENST00000400166CXADRchr2118885489+ENST00000357903APPchr2127425663-3148127842027647
ENST00000400166CXADRchr2118885489+ENST00000358918APPchr2127425663-3150127842030648
ENST00000400166CXADRchr2118885489+ENST00000359726APPchr2127425663-3036127841916610
ENST00000400166CXADRchr2118885489+ENST00000448388APPchr2127425663-2203127841859591
ENST00000400166CXADRchr2118885489+ENST00000440126APPchr2127425663-2367127842027647
ENST00000400166CXADRchr2118885489+ENST00000439274APPchr2127425663-2423127842084666
ENST00000356275CXADRchr2118885489+ENST00000346798APPchr2127425663-31214302000666
ENST00000356275CXADRchr2118885489+ENST00000354192APPchr2127425663-28964301775591
ENST00000356275CXADRchr2118885489+ENST00000348990APPchr2127425663-28964301775591
ENST00000356275CXADRchr2118885489+ENST00000357903APPchr2127425663-30644301943647
ENST00000356275CXADRchr2118885489+ENST00000358918APPchr2127425663-30664301946648
ENST00000356275CXADRchr2118885489+ENST00000359726APPchr2127425663-29524301832610
ENST00000356275CXADRchr2118885489+ENST00000448388APPchr2127425663-21194301775591
ENST00000356275CXADRchr2118885489+ENST00000440126APPchr2127425663-22834301943647
ENST00000356275CXADRchr2118885489+ENST00000439274APPchr2127425663-23394302000666
ENST00000400165CXADRchr2118885489+ENST00000346798APPchr2127425663-31214302000666
ENST00000400165CXADRchr2118885489+ENST00000354192APPchr2127425663-28964301775591
ENST00000400165CXADRchr2118885489+ENST00000348990APPchr2127425663-28964301775591
ENST00000400165CXADRchr2118885489+ENST00000357903APPchr2127425663-30644301943647
ENST00000400165CXADRchr2118885489+ENST00000358918APPchr2127425663-30664301946648
ENST00000400165CXADRchr2118885489+ENST00000359726APPchr2127425663-29524301832610
ENST00000400165CXADRchr2118885489+ENST00000448388APPchr2127425663-21194301775591
ENST00000400165CXADRchr2118885489+ENST00000440126APPchr2127425663-22834301943647
ENST00000400165CXADRchr2118885489+ENST00000439274APPchr2127425663-23394302000666
ENST00000306618CXADRchr2118885489+ENST00000346798APPchr2127425663-31214302000666
ENST00000306618CXADRchr2118885489+ENST00000354192APPchr2127425663-28964301775591
ENST00000306618CXADRchr2118885489+ENST00000348990APPchr2127425663-28964301775591
ENST00000306618CXADRchr2118885489+ENST00000357903APPchr2127425663-30644301943647
ENST00000306618CXADRchr2118885489+ENST00000358918APPchr2127425663-30664301946648
ENST00000306618CXADRchr2118885489+ENST00000359726APPchr2127425663-29524301832610
ENST00000306618CXADRchr2118885489+ENST00000448388APPchr2127425663-21194301775591
ENST00000306618CXADRchr2118885489+ENST00000440126APPchr2127425663-22834301943647
ENST00000306618CXADRchr2118885489+ENST00000439274APPchr2127425663-23394302000666
ENST00000400169CXADRchr2118885489+ENST00000346798APPchr2127425663-31214302000666
ENST00000400169CXADRchr2118885489+ENST00000354192APPchr2127425663-28964301775591
ENST00000400169CXADRchr2118885489+ENST00000348990APPchr2127425663-28964301775591
ENST00000400169CXADRchr2118885489+ENST00000357903APPchr2127425663-30644301943647
ENST00000400169CXADRchr2118885489+ENST00000358918APPchr2127425663-30664301946648
ENST00000400169CXADRchr2118885489+ENST00000359726APPchr2127425663-29524301832610
ENST00000400169CXADRchr2118885489+ENST00000448388APPchr2127425663-21194301775591
ENST00000400169CXADRchr2118885489+ENST00000440126APPchr2127425663-22834301943647
ENST00000400169CXADRchr2118885489+ENST00000439274APPchr2127425663-23394302000666

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000284878ENST00000346798CXADRchr2118885490+APPchr2127425664-0.0030054120.9969946
ENST00000284878ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0025453950.9974546
ENST00000284878ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0025453950.9974546
ENST00000284878ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0029619580.997038
ENST00000284878ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0025739780.997426
ENST00000284878ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0024795960.9975204
ENST00000284878ENST00000448388CXADRchr2118885490+APPchr2127425664-0.005577410.9944226
ENST00000284878ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0068427690.9931572
ENST00000284878ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0070468720.9929531
ENST00000400166ENST00000346798CXADRchr2118885490+APPchr2127425664-0.00222990.9977701
ENST00000400166ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0018170320.99818295
ENST00000400166ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0018170320.99818295
ENST00000400166ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0022183090.9977817
ENST00000400166ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0019584440.9980415
ENST00000400166ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0017362750.9982638
ENST00000400166ENST00000448388CXADRchr2118885490+APPchr2127425664-0.0039356130.99606436
ENST00000400166ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0048106820.9951893
ENST00000400166ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0051387260.9948613
ENST00000356275ENST00000346798CXADRchr2118885490+APPchr2127425664-0.0019342630.99806577
ENST00000356275ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000356275ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000356275ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0019625780.9980374
ENST00000356275ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0017111480.9982888
ENST00000356275ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0014958870.99850416
ENST00000356275ENST00000448388CXADRchr2118885490+APPchr2127425664-0.0033116460.9966884
ENST00000356275ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0040195140.9959805
ENST00000356275ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0042647480.99573517
ENST00000400165ENST00000346798CXADRchr2118885490+APPchr2127425664-0.0019342630.99806577
ENST00000400165ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000400165ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000400165ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0019625780.9980374
ENST00000400165ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0017111480.9982888
ENST00000400165ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0014958870.99850416
ENST00000400165ENST00000448388CXADRchr2118885490+APPchr2127425664-0.0033116460.9966884
ENST00000400165ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0040195140.9959805
ENST00000400165ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0042647480.99573517
ENST00000306618ENST00000346798CXADRchr2118885490+APPchr2127425664-0.0019342630.99806577
ENST00000306618ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000306618ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000306618ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0019625780.9980374
ENST00000306618ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0017111480.9982888
ENST00000306618ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0014958870.99850416
ENST00000306618ENST00000448388CXADRchr2118885490+APPchr2127425664-0.0033116460.9966884
ENST00000306618ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0040195140.9959805
ENST00000306618ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0042647480.99573517
ENST00000400169ENST00000346798CXADRchr2118885490+APPchr2127425664-0.0019342630.99806577
ENST00000400169ENST00000354192CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000400169ENST00000348990CXADRchr2118885490+APPchr2127425664-0.0015857660.9984143
ENST00000400169ENST00000357903CXADRchr2118885490+APPchr2127425664-0.0019625780.9980374
ENST00000400169ENST00000358918CXADRchr2118885490+APPchr2127425664-0.0017111480.9982888
ENST00000400169ENST00000359726CXADRchr2118885490+APPchr2127425664-0.0014958870.99850416
ENST00000400169ENST00000448388CXADRchr2118885490+APPchr2127425664-0.0033116460.9966884
ENST00000400169ENST00000440126CXADRchr2118885490+APPchr2127425664-0.0040195140.9959805
ENST00000400169ENST00000439274CXADRchr2118885490+APPchr2127425664-0.0042647480.99573517
ENST00000284878ENST00000346798CXADRchr2118885489+APPchr2127425663-0.0030054120.9969946
ENST00000284878ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0025453950.9974546
ENST00000284878ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0025453950.9974546
ENST00000284878ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0029619580.997038
ENST00000284878ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0025739780.997426
ENST00000284878ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0024795960.9975204
ENST00000284878ENST00000448388CXADRchr2118885489+APPchr2127425663-0.005577410.9944226
ENST00000284878ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0068427690.9931572
ENST00000284878ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0070468720.9929531
ENST00000400166ENST00000346798CXADRchr2118885489+APPchr2127425663-0.00222990.9977701
ENST00000400166ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0018170320.99818295
ENST00000400166ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0018170320.99818295
ENST00000400166ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0022183090.9977817
ENST00000400166ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0019584440.9980415
ENST00000400166ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0017362750.9982638
ENST00000400166ENST00000448388CXADRchr2118885489+APPchr2127425663-0.0039356130.99606436
ENST00000400166ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0048106820.9951893
ENST00000400166ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0051387260.9948613
ENST00000356275ENST00000346798CXADRchr2118885489+APPchr2127425663-0.0019342630.99806577
ENST00000356275ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000356275ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000356275ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0019625780.9980374
ENST00000356275ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0017111480.9982888
ENST00000356275ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0014958870.99850416
ENST00000356275ENST00000448388CXADRchr2118885489+APPchr2127425663-0.0033116460.9966884
ENST00000356275ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0040195140.9959805
ENST00000356275ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0042647480.99573517
ENST00000400165ENST00000346798CXADRchr2118885489+APPchr2127425663-0.0019342630.99806577
ENST00000400165ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000400165ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000400165ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0019625780.9980374
ENST00000400165ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0017111480.9982888
ENST00000400165ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0014958870.99850416
ENST00000400165ENST00000448388CXADRchr2118885489+APPchr2127425663-0.0033116460.9966884
ENST00000400165ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0040195140.9959805
ENST00000400165ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0042647480.99573517
ENST00000306618ENST00000346798CXADRchr2118885489+APPchr2127425663-0.0019342630.99806577
ENST00000306618ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000306618ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000306618ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0019625780.9980374
ENST00000306618ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0017111480.9982888
ENST00000306618ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0014958870.99850416
ENST00000306618ENST00000448388CXADRchr2118885489+APPchr2127425663-0.0033116460.9966884
ENST00000306618ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0040195140.9959805
ENST00000306618ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0042647480.99573517
ENST00000400169ENST00000346798CXADRchr2118885489+APPchr2127425663-0.0019342630.99806577
ENST00000400169ENST00000354192CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000400169ENST00000348990CXADRchr2118885489+APPchr2127425663-0.0015857660.9984143
ENST00000400169ENST00000357903CXADRchr2118885489+APPchr2127425663-0.0019625780.9980374
ENST00000400169ENST00000358918CXADRchr2118885489+APPchr2127425663-0.0017111480.9982888
ENST00000400169ENST00000359726CXADRchr2118885489+APPchr2127425663-0.0014958870.99850416
ENST00000400169ENST00000448388CXADRchr2118885489+APPchr2127425663-0.0033116460.9966884
ENST00000400169ENST00000440126CXADRchr2118885489+APPchr2127425663-0.0040195140.9959805
ENST00000400169ENST00000439274CXADRchr2118885489+APPchr2127425663-0.0042647480.99573517

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>20798_20798_1_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000346798_length(amino acids)=743AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSG
LTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEER

--------------------------------------------------------------

>20798_20798_2_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000348990_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_3_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000354192_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_4_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000357903_length(amino acids)=724AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERM
SQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKK
YVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRI
SYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFR
HDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFE

--------------------------------------------------------------

>20798_20798_5_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000358918_length(amino acids)=725AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEF
RHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFF

--------------------------------------------------------------

>20798_20798_6_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000359726_length(amino acids)=687AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVSQSLLKTT
QEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLE
QEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTH
LRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHS
FGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

--------------------------------------------------------------

>20798_20798_7_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000439274_length(amino acids)=743AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSG
LTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEER

--------------------------------------------------------------

>20798_20798_8_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000440126_length(amino acids)=724AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERM
SQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKK
YVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRI
SYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFR
HDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFE

--------------------------------------------------------------

>20798_20798_9_CXADR-APP_CXADR_chr21_18885489_ENST00000284878_APP_chr21_27425663_ENST00000448388_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_10_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_11_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_12_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_13_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_14_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_15_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_16_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_17_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_18_CXADR-APP_CXADR_chr21_18885489_ENST00000306618_APP_chr21_27425663_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_19_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_20_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_21_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_22_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_23_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_24_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_25_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_26_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_27_CXADR-APP_CXADR_chr21_18885489_ENST00000356275_APP_chr21_27425663_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_28_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_29_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_30_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_31_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_32_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_33_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_34_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_35_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_36_CXADR-APP_CXADR_chr21_18885489_ENST00000400165_APP_chr21_27425663_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_37_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_38_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_39_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_40_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_41_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_42_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_43_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_44_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_45_CXADR-APP_CXADR_chr21_18885489_ENST00000400166_APP_chr21_27425663_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_46_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_47_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_48_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_49_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_50_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_51_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_52_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_53_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_54_CXADR-APP_CXADR_chr21_18885489_ENST00000400169_APP_chr21_27425663_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_55_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000346798_length(amino acids)=743AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSG
LTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEER

--------------------------------------------------------------

>20798_20798_56_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000348990_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_57_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000354192_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_58_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000357903_length(amino acids)=724AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERM
SQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKK
YVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRI
SYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFR
HDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFE

--------------------------------------------------------------

>20798_20798_59_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000358918_length(amino acids)=725AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIKTEEISEVKMDAEF
RHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFF

--------------------------------------------------------------

>20798_20798_60_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000359726_length(amino acids)=687AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVSQSLLKTT
QEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLE
QEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTH
LRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHS
FGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

--------------------------------------------------------------

>20798_20798_61_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000439274_length(amino acids)=743AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENE
HAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYI
TALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQ
KEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSG
LTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEER

--------------------------------------------------------------

>20798_20798_62_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000440126_length(amino acids)=724AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAET
GPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERM
SQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKK
YVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRI
SYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFR
HDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFE

--------------------------------------------------------------

>20798_20798_63_CXADR-APP_CXADR_chr21_18885490_ENST00000284878_APP_chr21_27425664_ENST00000448388_length(amino acids)=668AA_BP=91
MPRQPHAAGEAGARSPARAAAGSDASSPAERGLGGGAEGAEVPPPPRASRERARRGEPGTRSESRLPAAAAHGTAATMALLLCFVLLCGV
VVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSD
VWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVRVPTTAASTP
DAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVE
AMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVP
AVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDA
RPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIH

--------------------------------------------------------------

>20798_20798_64_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_65_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_66_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_67_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_68_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_69_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_70_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_71_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_72_CXADR-APP_CXADR_chr21_18885490_ENST00000306618_APP_chr21_27425664_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_73_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_74_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_75_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_76_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_77_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_78_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_79_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_80_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_81_CXADR-APP_CXADR_chr21_18885490_ENST00000356275_APP_chr21_27425664_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_82_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_83_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_84_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_85_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_86_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_87_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_88_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_89_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_90_CXADR-APP_CXADR_chr21_18885490_ENST00000400165_APP_chr21_27425664_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_91_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_92_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_93_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

--------------------------------------------------------------

>20798_20798_94_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_95_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

--------------------------------------------------------------

>20798_20798_96_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

--------------------------------------------------------------

>20798_20798_97_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

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>20798_20798_98_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_99_CXADR-APP_CXADR_chr21_18885490_ENST00000400166_APP_chr21_27425664_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

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>20798_20798_100_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000346798_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

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>20798_20798_101_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000348990_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

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>20798_20798_102_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000354192_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

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>20798_20798_103_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000357903_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

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>20798_20798_104_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000358918_length(amino acids)=648AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEGSGLTNIK
TEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKM

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>20798_20798_105_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000359726_length(amino acids)=610AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKA
VIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDP
KKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVN
GEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKG

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>20798_20798_106_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000439274_length(amino acids)=666AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDA
VDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAM
LNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAV
AEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARP
AADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHG

--------------------------------------------------------------

>20798_20798_107_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000440126_length(amino acids)=647AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIPTTAASTPDAVDKYLETPGDENEHAHFQK
AKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAV
PPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYS
DDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKT
EEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQ

--------------------------------------------------------------

>20798_20798_108_CXADR-APP_CXADR_chr21_18885490_ENST00000400169_APP_chr21_27425664_ENST00000448388_length(amino acids)=591AA_BP=14
MALLLCFVLLCGVVVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESD
NVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVE
EVVRVPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANE
RQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYE
RMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSV
PANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVIT

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:18885490/chr21:27425664)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CXADR

P78310

APP

Q8NEU8

FUNCTION: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. {ECO:0000269|PubMed:11734628, ECO:0000269|PubMed:12297051, ECO:0000269|PubMed:15800062, ECO:0000269|PubMed:19064666, ECO:0000269|PubMed:9096397}.; FUNCTION: (Microbial infection) Acts as a receptor for adenovirus type C. {ECO:0000269|PubMed:10567268, ECO:0000269|PubMed:10666333, ECO:0000269|PubMed:12297051, ECO:0000269|PubMed:9733828}.; FUNCTION: (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6. {ECO:0000269|PubMed:10814575, ECO:0000269|PubMed:14978041}.FUNCTION: Multifunctional adapter protein that binds to various membrane receptors, nuclear factors and signaling proteins to regulate many processes, such as cell proliferation, immune response, endosomal trafficking and cell metabolism (PubMed:26583432, PubMed:15016378, PubMed:24879834). Regulates signaling pathway leading to cell proliferation through interaction with RAB5A and subunits of the NuRD/MeCP1 complex (PubMed:15016378). Plays a role in immune response by modulating phagocytosis, inflammatory and innate immune responses. In macrophages, enhances Fc-gamma receptor-mediated phagocytosis through interaction with RAB31 leading to activation of PI3K/Akt signaling. In response to LPS, modulates inflammatory responses by playing a key role on the regulation of TLR4 signaling and in the nuclear translocation of RELA/NF-kappa-B p65 and the secretion of pro- and anti-inflammatory cytokines. Also functions as a negative regulator of innate immune response via inhibition of AKT1 signaling pathway by forming a complex with APPL1 and PIK3R1 (By similarity). Plays a role in endosomal trafficking of TGFBR1 from the endosomes to the nucleus (PubMed:26583432). Plays a role in cell metabolism by regulating adiponecting ans insulin signaling pathways and adaptative thermogenesis (PubMed:24879834) (By similarity). In muscle, negatively regulates adiponectin-simulated glucose uptake and fatty acid oxidation by inhibiting adiponectin signaling pathway through APPL1 sequestration thereby antagonizing APPL1 action (By similarity). In muscles, negativeliy regulates insulin-induced plasma membrane recruitment of GLUT4 and glucose uptake through interaction with TBC1D1 (PubMed:24879834). Plays a role in cold and diet-induced adaptive thermogenesis by activating ventromedial hypothalamus (VMH) neurons throught AMPK inhibition which enhances sympathetic outflow to subcutaneous white adipose tissue (sWAT), sWAT beiging and cold tolerance (By similarity). Also plays a role in other signaling pathways namely Wnt/beta-catenin, HGF and glucocorticoid receptor signaling (PubMed:19433865) (By similarity). Positive regulator of beta-catenin/TCF-dependent transcription through direct interaction with RUVBL2/reptin resulting in the relief of RUVBL2-mediated repression of beta-catenin/TCF target genes by modulating the interactions within the beta-catenin-reptin-HDAC complex (PubMed:19433865). May affect adult neurogenesis in hippocampus and olfactory system via regulating the sensitivity of glucocorticoid receptor. Required for fibroblast migration through HGF cell signaling (By similarity). {ECO:0000250|UniProtKB:Q8K3G9, ECO:0000269|PubMed:15016378, ECO:0000269|PubMed:19433865, ECO:0000269|PubMed:24879834, ECO:0000269|PubMed:26583432}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218230_260118.33333333333333771.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218274_280118.33333333333333771.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216230_260118.33333333333333696.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216274_280118.33333333333333696.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115230_26062.333333333333336640.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115274_28062.333333333333336640.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217230_260118.33333333333333752.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217274_280118.33333333333333752.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217230_260118.33333333333333753.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217274_280118.33333333333333753.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217230_260118.33333333333333715.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217274_280118.33333333333333715.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217230_260113.33333333333333747.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217274_280113.33333333333333747.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218230_260118.33333333333333771.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218274_280118.33333333333333771.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216230_260118.33333333333333696.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216274_280118.33333333333333696.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115230_26062.333333333333336640.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115274_28062.333333333333336640.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217230_260118.33333333333333752.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217274_280118.33333333333333752.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217230_260118.33333333333333753.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217274_280118.33333333333333753.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217230_260118.33333333333333715.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217274_280118.33333333333333715.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217230_260113.33333333333333747.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217274_280113.33333333333333747.0Compositional biasNote=Poly-Thr
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218374_565118.33333333333333771.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216374_565118.33333333333333696.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115374_56562.333333333333336640.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217374_565118.33333333333333752.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217374_565118.33333333333333753.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217374_565118.33333333333333715.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217374_565113.33333333333333747.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218374_565118.33333333333333771.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216374_565118.33333333333333696.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115374_56562.333333333333336640.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217374_565118.33333333333333752.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217374_565118.33333333333333753.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217374_565118.33333333333333715.0DomainE2
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217374_565113.33333333333333747.0DomainE2
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218344_365118.33333333333333771.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218724_734118.33333333333333771.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216344_365118.33333333333333696.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216724_734118.33333333333333696.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115344_36562.333333333333336640.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115724_73462.333333333333336640.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217344_365118.33333333333333752.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217724_734118.33333333333333752.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217344_365118.33333333333333753.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217724_734118.33333333333333753.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217344_365118.33333333333333715.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217724_734118.33333333333333715.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217344_365113.33333333333333747.0MotifOX-2
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217724_734113.33333333333333747.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218344_365118.33333333333333771.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218724_734118.33333333333333771.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216344_365118.33333333333333696.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216724_734118.33333333333333696.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115344_36562.333333333333336640.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115724_73462.333333333333336640.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217344_365118.33333333333333752.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217724_734118.33333333333333752.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217344_365118.33333333333333753.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217724_734118.33333333333333753.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217344_365118.33333333333333715.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217724_734118.33333333333333715.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217344_365113.33333333333333747.0MotifOX-2
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217724_734113.33333333333333747.0MotifNote=Basolateral sorting signal
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218131_189118.33333333333333771.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218181_188118.33333333333333771.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218391_423118.33333333333333771.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218491_522118.33333333333333771.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218523_540118.33333333333333771.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216131_189118.33333333333333696.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216181_188118.33333333333333696.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216391_423118.33333333333333696.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216491_522118.33333333333333696.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216523_540118.33333333333333696.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115131_18962.333333333333336640.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115181_18862.333333333333336640.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115391_42362.333333333333336640.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115491_52262.333333333333336640.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115523_54062.333333333333336640.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000035419211596_11062.333333333333336640.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217131_189118.33333333333333752.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217181_188118.33333333333333752.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217391_423118.33333333333333752.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217491_522118.33333333333333752.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217523_540118.33333333333333752.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217131_189118.33333333333333753.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217181_188118.33333333333333753.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217391_423118.33333333333333753.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217491_522118.33333333333333753.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217523_540118.33333333333333753.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217131_189118.33333333333333715.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217181_188118.33333333333333715.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217391_423118.33333333333333715.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217491_522118.33333333333333715.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217523_540118.33333333333333715.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217131_189113.33333333333333747.0RegionCuBD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217181_188113.33333333333333747.0RegionNote=Zinc-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217391_423113.33333333333333747.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217491_522113.33333333333333747.0RegionNote=Heparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217523_540113.33333333333333747.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218131_189118.33333333333333771.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218181_188118.33333333333333771.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218391_423118.33333333333333771.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218491_522118.33333333333333771.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218523_540118.33333333333333771.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216131_189118.33333333333333696.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216181_188118.33333333333333696.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216391_423118.33333333333333696.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216491_522118.33333333333333696.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216523_540118.33333333333333696.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115131_18962.333333333333336640.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115181_18862.333333333333336640.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115391_42362.333333333333336640.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115491_52262.333333333333336640.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115523_54062.333333333333336640.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000035419211596_11062.333333333333336640.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217131_189118.33333333333333752.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217181_188118.33333333333333752.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217391_423118.33333333333333752.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217491_522118.33333333333333752.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217523_540118.33333333333333752.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217131_189118.33333333333333753.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217181_188118.33333333333333753.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217391_423118.33333333333333753.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217491_522118.33333333333333753.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217523_540118.33333333333333753.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217131_189118.33333333333333715.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217181_188118.33333333333333715.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217391_423118.33333333333333715.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217491_522118.33333333333333715.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217523_540118.33333333333333715.0RegionCollagen-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217131_189113.33333333333333747.0RegionCuBD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217181_188113.33333333333333747.0RegionNote=Zinc-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217391_423113.33333333333333747.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217491_522113.33333333333333747.0RegionNote=Heparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217523_540113.33333333333333747.0RegionCollagen-binding
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218723_770118.33333333333333771.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216723_770118.33333333333333696.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115723_77062.333333333333336640.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217723_770118.33333333333333752.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217723_770118.33333333333333753.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217723_770118.33333333333333715.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217723_770113.33333333333333747.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218723_770118.33333333333333771.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216723_770118.33333333333333696.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115723_77062.333333333333336640.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217723_770118.33333333333333752.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217723_770118.33333333333333753.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217723_770118.33333333333333715.0Topological domainCytoplasmic
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217723_770113.33333333333333747.0Topological domainCytoplasmic
TgeneAPPchr21:18885489chr21:27425663ENST00000346798218702_722118.33333333333333771.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000348990216702_722118.33333333333333696.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000354192115702_72262.333333333333336640.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000357903217702_722118.33333333333333752.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000358918217702_722118.33333333333333753.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000359726217702_722118.33333333333333715.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST00000440126217702_722113.33333333333333747.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000346798218702_722118.33333333333333771.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000348990216702_722118.33333333333333696.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000354192115702_72262.333333333333336640.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000357903217702_722118.33333333333333752.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000358918217702_722118.33333333333333753.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000359726217702_722118.33333333333333715.0TransmembraneHelical
TgeneAPPchr21:18885490chr21:27425664ENST00000440126217702_722113.33333333333333747.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+17141_22814.333333333333334366.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+1720_13414.333333333333334366.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+16141_22814.333333333333334325.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+1620_13414.333333333333334325.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+13141_22814.33333333333333490.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+1320_13414.33333333333333490.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+14141_22814.333333333333334201.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+1420_13414.333333333333334201.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+15141_22814.333333333333334253.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+1520_13414.333333333333334253.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+18141_22814.333333333333334353.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+1820_13414.333333333333334353.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+17141_22814.333333333333334366.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+1720_13414.333333333333334366.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+16141_22814.333333333333334325.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+1620_13414.333333333333334325.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+13141_22814.33333333333333490.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+1320_13414.33333333333333490.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+14141_22814.333333333333334201.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+1420_13414.333333333333334201.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+15141_22814.333333333333334253.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+1520_13414.333333333333334253.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+18141_22814.333333333333334353.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+1820_13414.333333333333334353.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+17360_36514.333333333333334366.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+16360_36514.333333333333334325.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+13360_36514.33333333333333490.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+14360_36514.333333333333334201.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+15360_36514.333333333333334253.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+18360_36514.333333333333334353.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+17360_36514.333333333333334366.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+16360_36514.333333333333334325.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+13360_36514.33333333333333490.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+14360_36514.333333333333334201.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+15360_36514.333333333333334253.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+18360_36514.333333333333334353.0MotifNote=PDZ-binding
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+1720_23714.333333333333334366.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+17259_36514.333333333333334366.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+1620_23714.333333333333334325.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+16259_36514.333333333333334325.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+1320_23714.33333333333333490.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+13259_36514.33333333333333490.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+1420_23714.333333333333334201.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+14259_36514.333333333333334201.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+1520_23714.333333333333334253.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+15259_36514.333333333333334253.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+1820_23714.333333333333334353.0Topological domainExtracellular
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+18259_36514.333333333333334353.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+1720_23714.333333333333334366.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+17259_36514.333333333333334366.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+1620_23714.333333333333334325.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+16259_36514.333333333333334325.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+1320_23714.33333333333333490.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+13259_36514.33333333333333490.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+1420_23714.333333333333334201.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+14259_36514.333333333333334201.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+1520_23714.333333333333334253.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+15259_36514.333333333333334253.0Topological domainCytoplasmic
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+1820_23714.333333333333334353.0Topological domainExtracellular
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+18259_36514.333333333333334353.0Topological domainCytoplasmic
HgeneCXADRchr21:18885489chr21:27425663ENST00000284878+17238_25814.333333333333334366.0TransmembraneHelical
HgeneCXADRchr21:18885489chr21:27425663ENST00000306618+16238_25814.333333333333334325.0TransmembraneHelical
HgeneCXADRchr21:18885489chr21:27425663ENST00000356275+13238_25814.33333333333333490.0TransmembraneHelical
HgeneCXADRchr21:18885489chr21:27425663ENST00000400165+14238_25814.333333333333334201.0TransmembraneHelical
HgeneCXADRchr21:18885489chr21:27425663ENST00000400166+15238_25814.333333333333334253.0TransmembraneHelical
HgeneCXADRchr21:18885489chr21:27425663ENST00000400169+18238_25814.333333333333334353.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000284878+17238_25814.333333333333334366.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000306618+16238_25814.333333333333334325.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000356275+13238_25814.33333333333333490.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000400165+14238_25814.333333333333334201.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000400166+15238_25814.333333333333334253.0TransmembraneHelical
HgeneCXADRchr21:18885490chr21:27425664ENST00000400169+18238_25814.333333333333334353.0TransmembraneHelical
TgeneAPPchr21:18885489chr21:27425663ENST0000034679821828_189118.33333333333333771.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000034899021628_189118.33333333333333696.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000035419211528_18962.333333333333336640.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000035790321728_189118.33333333333333752.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000035891821728_189118.33333333333333753.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000035972621728_189118.33333333333333715.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000044012621728_189113.33333333333333747.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000034679821828_189118.33333333333333771.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000034899021628_189118.33333333333333696.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000035419211528_18962.333333333333336640.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000035790321728_189118.33333333333333752.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000035891821728_189118.33333333333333753.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000035972621728_189118.33333333333333715.0DomainE1
TgeneAPPchr21:18885490chr21:27425664ENST0000044012621728_189113.33333333333333747.0DomainE1
TgeneAPPchr21:18885489chr21:27425663ENST0000034679821828_123118.33333333333333771.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000034679821896_110118.33333333333333771.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000034899021628_123118.33333333333333696.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000034899021696_110118.33333333333333696.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000035419211528_12362.333333333333336640.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000035790321728_123118.33333333333333752.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000035790321796_110118.33333333333333752.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000035891821728_123118.33333333333333753.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000035891821796_110118.33333333333333753.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000035972621728_123118.33333333333333715.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000035972621796_110118.33333333333333715.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000044012621728_123113.33333333333333747.0RegionGFLD subdomain
TgeneAPPchr21:18885489chr21:27425663ENST0000044012621796_110113.33333333333333747.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000034679821828_123118.33333333333333771.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000034679821896_110118.33333333333333771.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000034899021628_123118.33333333333333696.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000034899021696_110118.33333333333333696.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000035419211528_12362.333333333333336640.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000035790321728_123118.33333333333333752.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000035790321796_110118.33333333333333752.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000035891821728_123118.33333333333333753.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000035891821796_110118.33333333333333753.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000035972621728_123118.33333333333333715.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000035972621796_110118.33333333333333715.0RegionHeparin-binding
TgeneAPPchr21:18885490chr21:27425664ENST0000044012621728_123113.33333333333333747.0RegionGFLD subdomain
TgeneAPPchr21:18885490chr21:27425664ENST0000044012621796_110113.33333333333333747.0RegionHeparin-binding
TgeneAPPchr21:18885489chr21:27425663ENST0000034679821818_701118.33333333333333771.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000034899021618_701118.33333333333333696.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000035419211518_70162.333333333333336640.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000035790321718_701118.33333333333333752.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000035891821718_701118.33333333333333753.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000035972621718_701118.33333333333333715.0Topological domainExtracellular
TgeneAPPchr21:18885489chr21:27425663ENST0000044012621718_701113.33333333333333747.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000034679821818_701118.33333333333333771.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000034899021618_701118.33333333333333696.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000035419211518_70162.333333333333336640.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000035790321718_701118.33333333333333752.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000035891821718_701118.33333333333333753.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000035972621718_701118.33333333333333715.0Topological domainExtracellular
TgeneAPPchr21:18885490chr21:27425664ENST0000044012621718_701113.33333333333333747.0Topological domainExtracellular


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
CXADR_pLDDT.png
all structure
all structure
APP_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
CXADR
APP


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to CXADR-APP


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to CXADR-APP


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource