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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:DDR1-PAK1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: DDR1-PAK1
FusionPDB ID: 21845
FusionGDB2.0 ID: 21845
HgeneTgene
Gene symbol

DDR1

PAK1

Gene ID

780

5585

Gene namediscoidin domain receptor tyrosine kinase 1protein kinase N1
SynonymsCAK|CD167|DDR|EDDR1|HGK2|MCK10|NEP|NTRK4|PTK3|PTK3A|RTK6|TRKEDBK|PAK-1|PAK1|PKN|PKN-ALPHA|PRK1|PRKCL1
Cytomap

6p21.33

19p13.12

Type of geneprotein-codingprotein-coding
Descriptionepithelial discoidin domain-containing receptor 1CD167 antigen-like family member APTK3A protein tyrosine kinase 3Acell adhesion kinasemammary carcinoma kinase 10neuroepithelial tyrosine kinaseneurotrophic tyrosine kinase, receptor, type 4protein-tserine/threonine-protein kinase N1protease-activated kinase 1protein kinase C-like 1protein kinase C-like PKNprotein kinase C-related kinase 1protein kinase PKN-alphaserine-threonine kinase Nserine/threonine protein kinase N
Modification date2020032920200329
UniProtAcc

Q08345

.
Ensembl transtripts involved in fusion geneENST idsENST00000446312, ENST00000324771, 
ENST00000361741, ENST00000376567, 
ENST00000376568, ENST00000376569, 
ENST00000376570, ENST00000376575, 
ENST00000418800, ENST00000452441, 
ENST00000454612, ENST00000508312, 
ENST00000513240, ENST00000259875, 
ENST00000383377, ENST00000400410, 
ENST00000400411, ENST00000400414, 
ENST00000400486, ENST00000400488, 
ENST00000400489, ENST00000400491, 
ENST00000400492, ENST00000412329, 
ENST00000415092, ENST00000419412, 
ENST00000421229, ENST00000422628, 
ENST00000427053, ENST00000429699, 
ENST00000430933, ENST00000434428, 
ENST00000449518, ENST00000453510, 
ENST00000454774, ENST00000462241, 
ENST00000468225, ENST00000483193, 
ENST00000487780, ENST00000488414, 
ENST00000490712, ENST00000508472, 
ENST00000548133, ENST00000548693, 
ENST00000548962, ENST00000549026, 
ENST00000550384, ENST00000550395, 
ENST00000550666, ENST00000552068, 
ENST00000552434, ENST00000552721, 
ENST00000553015, 		ENST00000278568, 
ENST00000356341, ENST00000528203, 
ENST00000530617, ENST00000525542, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score6 X 6 X 4=14422 X 17 X 10=3740
# samples 626
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/3740*10)=-3.84645474174655
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: DDR1 [Title/Abstract] AND PAK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)DDR1(30861200)-PAK1(77070062), # samples:3
Anticipated loss of major functional domain due to fusion event.DDR1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DDR1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DDR1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DDR1-PAK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDDR1

GO:0038063

collagen-activated tyrosine kinase receptor signaling pathway

9659899|21044884

HgeneDDR1

GO:0038083

peptidyl-tyrosine autophosphorylation

21044884

HgeneDDR1

GO:0046777

protein autophosphorylation

9659899

TgenePAK1

GO:0006357

regulation of transcription by RNA polymerase II

12514133

TgenePAK1

GO:0006468

protein phosphorylation

17332740

TgenePAK1

GO:0035407

histone H3-T11 phosphorylation

18066052


check buttonFusion gene breakpoints across DDR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PAK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-1477-01ADDR1chr6

30861200

-PAK1chr11

77070062

-
ChimerDB4OVTCGA-13-1477-01ADDR1chr6

30861200

+PAK1chr11

77070062

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000324771DDR1chr630861200+ENST00000356341PAK1chr1177070062-462318955483055835
ENST00000324771DDR1chr630861200+ENST00000530617PAK1chr1177070062-410718955482986812
ENST00000324771DDR1chr630861200+ENST00000278568PAK1chr1177070062-343118955483079843
ENST00000324771DDR1chr630861200+ENST00000528203PAK1chr1177070062-335518955483079843
ENST00000418800DDR1chr630861200+ENST00000356341PAK1chr1177070062-448817603532920855
ENST00000418800DDR1chr630861200+ENST00000530617PAK1chr1177070062-397217603532851832
ENST00000418800DDR1chr630861200+ENST00000278568PAK1chr1177070062-329617603532944863
ENST00000418800DDR1chr630861200+ENST00000528203PAK1chr1177070062-322017603532944863
ENST00000454612DDR1chr630861200+ENST00000356341PAK1chr1177070062-452617984512958835
ENST00000454612DDR1chr630861200+ENST00000530617PAK1chr1177070062-401017984512889812
ENST00000454612DDR1chr630861200+ENST00000278568PAK1chr1177070062-333417984512982843
ENST00000454612DDR1chr630861200+ENST00000528203PAK1chr1177070062-325817984512982843
ENST00000376569DDR1chr630861200+ENST00000356341PAK1chr1177070062-436716392922799835
ENST00000376569DDR1chr630861200+ENST00000530617PAK1chr1177070062-385116392922730812
ENST00000376569DDR1chr630861200+ENST00000278568PAK1chr1177070062-317516392922823843
ENST00000376569DDR1chr630861200+ENST00000528203PAK1chr1177070062-309916392922823843
ENST00000376575DDR1chr630861200+ENST00000356341PAK1chr1177070062-440816803332840835
ENST00000376575DDR1chr630861200+ENST00000530617PAK1chr1177070062-389216803332771812
ENST00000376575DDR1chr630861200+ENST00000278568PAK1chr1177070062-321616803332864843
ENST00000376575DDR1chr630861200+ENST00000528203PAK1chr1177070062-314016803332864843
ENST00000376570DDR1chr630861200+ENST00000356341PAK1chr1177070062-440816803332840835
ENST00000376570DDR1chr630861200+ENST00000530617PAK1chr1177070062-389216803332771812
ENST00000376570DDR1chr630861200+ENST00000278568PAK1chr1177070062-321616803332864843
ENST00000376570DDR1chr630861200+ENST00000528203PAK1chr1177070062-314016803332864843
ENST00000376568DDR1chr630861200+ENST00000356341PAK1chr1177070062-437016422952802835
ENST00000376568DDR1chr630861200+ENST00000530617PAK1chr1177070062-385416422952733812
ENST00000376568DDR1chr630861200+ENST00000278568PAK1chr1177070062-317816422952826843
ENST00000376568DDR1chr630861200+ENST00000528203PAK1chr1177070062-310216422952826843
ENST00000452441DDR1chr630861200+ENST00000356341PAK1chr1177070062-433416062592766835
ENST00000452441DDR1chr630861200+ENST00000530617PAK1chr1177070062-381816062592697812
ENST00000452441DDR1chr630861200+ENST00000278568PAK1chr1177070062-314216062592790843
ENST00000452441DDR1chr630861200+ENST00000528203PAK1chr1177070062-306616062592790843
ENST00000508312DDR1chr630861200+ENST00000356341PAK1chr1177070062-438116532522813853
ENST00000508312DDR1chr630861200+ENST00000530617PAK1chr1177070062-386516532522744830
ENST00000508312DDR1chr630861200+ENST00000278568PAK1chr1177070062-318916532522837861
ENST00000508312DDR1chr630861200+ENST00000528203PAK1chr1177070062-311316532522837861
ENST00000376567DDR1chr630861200+ENST00000356341PAK1chr1177070062-441616882932848851
ENST00000376567DDR1chr630861200+ENST00000530617PAK1chr1177070062-390016882932779828
ENST00000376567DDR1chr630861200+ENST00000278568PAK1chr1177070062-322416882932872859
ENST00000376567DDR1chr630861200+ENST00000528203PAK1chr1177070062-314816882932872859
ENST00000513240DDR1chr630861200+ENST00000356341PAK1chr1177070062-4075134702507835
ENST00000513240DDR1chr630861200+ENST00000530617PAK1chr1177070062-3559134702438812
ENST00000513240DDR1chr630861200+ENST00000278568PAK1chr1177070062-2883134702531843
ENST00000513240DDR1chr630861200+ENST00000528203PAK1chr1177070062-2807134702531843
ENST00000361741DDR1chr630861200+ENST00000356341PAK1chr1177070062-3463735541895613
ENST00000361741DDR1chr630861200+ENST00000530617PAK1chr1177070062-2947735541826590
ENST00000361741DDR1chr630861200+ENST00000278568PAK1chr1177070062-2271735541919621
ENST00000361741DDR1chr630861200+ENST00000528203PAK1chr1177070062-2195735541919621

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000324771ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.003546350.99645364
ENST00000324771ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0045075070.99549246
ENST00000324771ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0058601020.9941399
ENST00000324771ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0072876220.9927124
ENST00000418800ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0029306010.9970694
ENST00000418800ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0038448810.9961551
ENST00000418800ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0047496020.99525034
ENST00000418800ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0059312350.99406874
ENST00000454612ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0031715750.9968284
ENST00000454612ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0040404260.9959596
ENST00000454612ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0051019790.994898
ENST00000454612ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0063667590.9936333
ENST00000376569ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0032386190.9967614
ENST00000376569ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.004177760.9958222
ENST00000376569ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0055365430.9944635
ENST00000376569ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0070012350.9929987
ENST00000376575ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0033642950.99663574
ENST00000376575ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0043037850.9956962
ENST00000376575ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0056654230.9943346
ENST00000376575ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0071459890.99285406
ENST00000376570ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0033642950.99663574
ENST00000376570ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0043037850.9956962
ENST00000376570ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0056654230.9943346
ENST00000376570ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0071459890.99285406
ENST00000376568ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0033191030.9966809
ENST00000376568ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0042451350.99575484
ENST00000376568ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0056603560.99433964
ENST00000376568ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0071598120.9928402
ENST00000452441ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0033791460.9966209
ENST00000452441ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0043422270.9956578
ENST00000452441ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0057655580.9942345
ENST00000452441ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0072865180.9927135
ENST00000508312ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0033682880.9966317
ENST00000508312ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0043322840.9956677
ENST00000508312ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0056994350.9943006
ENST00000508312ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0071693710.9928307
ENST00000376567ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0020357170.99796426
ENST00000376567ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.0026281570.9973718
ENST00000376567ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0033252240.9966748
ENST00000376567ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0041578550.99584216
ENST00000513240ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.0028958390.9971041
ENST00000513240ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.003799670.99620026
ENST00000513240ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0051999050.9948001
ENST00000513240ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0067056190.9932943
ENST00000361741ENST00000356341DDR1chr630861200+PAK1chr1177070062-0.004252380.9957476
ENST00000361741ENST00000530617DDR1chr630861200+PAK1chr1177070062-0.005069430.99493057
ENST00000361741ENST00000278568DDR1chr630861200+PAK1chr1177070062-0.0090538350.9909462
ENST00000361741ENST00000528203DDR1chr630861200+PAK1chr1177070062-0.0115640520.988436

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>21845_21845_1_DDR1-PAK1_DDR1_chr6_30861200_ENST00000324771_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_2_DDR1-PAK1_DDR1_chr6_30861200_ENST00000324771_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_3_DDR1-PAK1_DDR1_chr6_30861200_ENST00000324771_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_4_DDR1-PAK1_DDR1_chr6_30861200_ENST00000324771_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_5_DDR1-PAK1_DDR1_chr6_30861200_ENST00000361741_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=621AA_BP=227
MQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMA
WEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEP
RGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYT
RSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS
NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA

--------------------------------------------------------------

>21845_21845_6_DDR1-PAK1_DDR1_chr6_30861200_ENST00000361741_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=613AA_BP=227
MQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMA
WEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEP
RGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYT
RSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS
NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA

--------------------------------------------------------------

>21845_21845_7_DDR1-PAK1_DDR1_chr6_30861200_ENST00000361741_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=621AA_BP=227
MQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMA
WEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEP
RGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYT
RSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS
NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA

--------------------------------------------------------------

>21845_21845_8_DDR1-PAK1_DDR1_chr6_30861200_ENST00000361741_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=590AA_BP=227
MQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMA
WEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEP
RGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYT
RSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS
NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA

--------------------------------------------------------------

>21845_21845_9_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376567_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=859AA_BP=465
MQRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWC
PAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLV
RFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYD
YVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVAR
FLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLII
ALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDA
LTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN
PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQI
TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEM

--------------------------------------------------------------

>21845_21845_10_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376567_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=851AA_BP=465
MQRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWC
PAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLV
RFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYD
YVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVAR
FLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLII
ALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDA
LTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN
PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQI
TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEM

--------------------------------------------------------------

>21845_21845_11_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376567_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=859AA_BP=465
MQRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWC
PAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLV
RFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYD
YVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVAR
FLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLII
ALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDA
LTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN
PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQI
TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEM

--------------------------------------------------------------

>21845_21845_12_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376567_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=828AA_BP=465
MQRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWC
PAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLV
RFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYD
YVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVAR
FLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLII
ALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDA
LTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKN
PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQI
TPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEM

--------------------------------------------------------------

>21845_21845_13_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376568_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_14_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376568_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_15_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376568_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_16_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376568_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_17_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376569_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_18_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376569_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_19_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376569_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_20_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376569_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_21_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376570_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_22_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376570_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_23_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376570_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_24_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376570_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_25_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376575_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_26_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376575_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_27_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376575_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_28_DDR1-PAK1_DDR1_chr6_30861200_ENST00000376575_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_29_DDR1-PAK1_DDR1_chr6_30861200_ENST00000418800_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=863AA_BP=469
MLFSGGRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGD
GAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVW
PGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGG
RVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLL
LLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTT
PPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMR
ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGF
CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNR

--------------------------------------------------------------

>21845_21845_30_DDR1-PAK1_DDR1_chr6_30861200_ENST00000418800_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=855AA_BP=469
MLFSGGRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGD
GAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVW
PGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGG
RVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLL
LLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTT
PPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMR
ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGF
CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNR

--------------------------------------------------------------

>21845_21845_31_DDR1-PAK1_DDR1_chr6_30861200_ENST00000418800_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=863AA_BP=469
MLFSGGRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGD
GAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVW
PGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGG
RVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLL
LLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTT
PPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMR
ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGF
CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNR

--------------------------------------------------------------

>21845_21845_32_DDR1-PAK1_DDR1_chr6_30861200_ENST00000418800_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=832AA_BP=469
MLFSGGRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGD
GAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMV
ARLVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVW
PGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGG
RVARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLL
LLIIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTT
PPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMR
ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGF
CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNR

--------------------------------------------------------------

>21845_21845_33_DDR1-PAK1_DDR1_chr6_30861200_ENST00000452441_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_34_DDR1-PAK1_DDR1_chr6_30861200_ENST00000452441_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_35_DDR1-PAK1_DDR1_chr6_30861200_ENST00000452441_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_36_DDR1-PAK1_DDR1_chr6_30861200_ENST00000452441_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_37_DDR1-PAK1_DDR1_chr6_30861200_ENST00000454612_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_38_DDR1-PAK1_DDR1_chr6_30861200_ENST00000454612_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_39_DDR1-PAK1_DDR1_chr6_30861200_ENST00000454612_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_40_DDR1-PAK1_DDR1_chr6_30861200_ENST00000454612_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

--------------------------------------------------------------

>21845_21845_41_DDR1-PAK1_DDR1_chr6_30861200_ENST00000508312_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=861AA_BP=467
MSLPRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGA
WCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVAR
LVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPG
YDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRV
ARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLL
IIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPP
DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMREN
KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCL

--------------------------------------------------------------

>21845_21845_42_DDR1-PAK1_DDR1_chr6_30861200_ENST00000508312_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=853AA_BP=467
MSLPRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGA
WCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVAR
LVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPG
YDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRV
ARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLL
IIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPP
DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMREN
KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCL

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>21845_21845_43_DDR1-PAK1_DDR1_chr6_30861200_ENST00000508312_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=861AA_BP=467
MSLPRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGA
WCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVAR
LVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPG
YDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRV
ARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLL
IIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPP
DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMREN
KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCL

--------------------------------------------------------------

>21845_21845_44_DDR1-PAK1_DDR1_chr6_30861200_ENST00000508312_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=830AA_BP=467
MSLPRCCPHPLRPEGSGAMGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGA
WCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVAR
LVRFYPRADRVMSVCLRVELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPG
YDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRV
ARFLQCRFLFAGPWLLFSEISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLL
IIALMLWRLHWRRLLSKNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPP
DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMREN
KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCL

--------------------------------------------------------------

>21845_21845_45_DDR1-PAK1_DDR1_chr6_30861200_ENST00000513240_PAK1_chr11_77070062_ENST00000278568_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_46_DDR1-PAK1_DDR1_chr6_30861200_ENST00000513240_PAK1_chr11_77070062_ENST00000356341_length(amino acids)=835AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQF

--------------------------------------------------------------

>21845_21845_47_DDR1-PAK1_DDR1_chr6_30861200_ENST00000513240_PAK1_chr11_77070062_ENST00000528203_length(amino acids)=843AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQVRK

--------------------------------------------------------------

>21845_21845_48_DDR1-PAK1_DDR1_chr6_30861200_ENST00000513240_PAK1_chr11_77070062_ENST00000530617_length(amino acids)=812AA_BP=449
MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAARHSRLESSDGDGAWCPAGSVFPKEEEYLQVD
LQRLHLVALVGTQGRHAGGLGKEFSRSYRLRYSRDGRRWMGWKDRWGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMSVCLRV
ELYGCLWRDGLLSYTAPVGQTMYLSEAVYLNDSTYDGHTVGGLQYGGLGQLADGVVGLDDFRKSQELRVWPGYDYVGWSNHSFSSGYVEM
EFEFDRLRAFQAMQVHCNNMHTLGARLPGGVECRFRRGPAMAWEGEPMRHNLGGNLGDPRARAVSVPLGGRVARFLQCRFLFAGPWLLFS
EISFISDVVNNSSPALGGTFPPAPWWPPGPPPTNFSSLELEPRGQQPVAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHWRRLLSKN
VKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSD
EEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDEL
WVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHSS

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Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:30861200/chr11:77070062)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DDR1

Q08345

.
FUNCTION: Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing (By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. {ECO:0000250, ECO:0000269|PubMed:12065315, ECO:0000269|PubMed:16234985, ECO:0000269|PubMed:16337946, ECO:0000269|PubMed:19401332, ECO:0000269|PubMed:20093046, ECO:0000269|PubMed:20432435, ECO:0000269|PubMed:20884741, ECO:0000269|PubMed:21044884, ECO:0000269|PubMed:9659899}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220377_415449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916377_415449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018377_415449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118377_415449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219377_415449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220377_415449.0920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017377_415449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118377_415415.6666666666667646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119377_415449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421377_415449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017377_415467.0895.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917377_415449.0920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220192_367449.0914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916192_367449.0877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018192_367449.0914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118192_367449.0877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219192_367449.0877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220192_367449.0920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017192_367449.0877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118192_367415.6666666666667646.3333333333334RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119192_367449.0914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421192_367449.0877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017192_367467.0895.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917192_367449.0920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+122021_417449.0914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+91621_417449.0877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+101821_417449.0914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+111821_417449.0877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+121921_417449.0877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+122021_417449.0920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+101721_417449.0877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+111821_417415.6666666666667646.3333333333334Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+111921_417449.0914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+142121_417449.0877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+101721_417467.0895.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+91721_417449.0920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220418_438449.0914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916418_438449.0877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018418_438449.0914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118418_438449.0877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219418_438449.0877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220418_438449.0920.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017418_438449.0877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119418_438449.0914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421418_438449.0877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017418_438467.0895.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917418_438449.0920.0TransmembraneHelical
TgenePAK1chr6:30861200chr11:77070062ENST00000278568416270_521159.0554.0DomainProtein kinase
TgenePAK1chr6:30861200chr11:77070062ENST00000356341415270_521159.0546.0DomainProtein kinase
TgenePAK1chr6:30861200chr11:77070062ENST00000278568416276_284159.0554.0Nucleotide bindingNote=ATP
TgenePAK1chr6:30861200chr11:77070062ENST00000278568416345_347159.0554.0Nucleotide bindingNote=ATP
TgenePAK1chr6:30861200chr11:77070062ENST00000356341415276_284159.0546.0Nucleotide bindingNote=ATP
TgenePAK1chr6:30861200chr11:77070062ENST00000356341415345_347159.0546.0Nucleotide bindingNote=ATP

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220476_601449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916476_601449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018476_601449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118476_601449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219476_601449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220476_601449.0920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017476_601449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118476_601415.6666666666667646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119377_4150914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119476_6010914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119476_601449.0914.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421476_601449.0877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117377_4150877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117476_6010877.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017476_601467.0895.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917476_601449.0920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120377_4150920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120476_6010920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118377_4150646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118476_6010646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118377_4150646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118476_6010646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118377_4150646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118476_6010646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120377_4150920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120476_6010920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120377_4150920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120476_6010920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118377_4150646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118476_6010646.3333333333334Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120377_4150920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120476_6010920.0Compositional biasNote=Gly/Pro-rich
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220610_905449.0914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916610_905449.0877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018610_905449.0914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118610_905449.0877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219610_905449.0877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220610_905449.0920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017610_905449.0877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118610_905415.6666666666667646.3333333333334DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119610_9050914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119610_905449.0914.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421610_905449.0877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117610_9050877.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017610_905467.0895.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917610_905449.0920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120610_9050920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118610_9050646.3333333333334DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118610_9050646.3333333333334DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118610_9050646.3333333333334DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120610_9050920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120610_9050920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118610_9050646.3333333333334DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120610_9050920.0DomainProtein kinase
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220481_484449.0914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916481_484449.0877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018481_484449.0914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118481_484449.0877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219481_484449.0877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220481_484449.0920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017481_484449.0877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118481_484415.6666666666667646.3333333333334MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119481_4840914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119481_484449.0914.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421481_484449.0877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117481_4840877.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017481_484467.0895.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917481_484449.0920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120481_4840920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118481_4840646.3333333333334MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118481_4840646.3333333333334MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118481_4840646.3333333333334MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120481_4840920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120481_4840920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118481_4840646.3333333333334MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120481_4840920.0MotifNote=PPxY motif
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220616_624449.0914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916616_624449.0877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018616_624449.0914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118616_624449.0877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219616_624449.0877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220616_624449.0920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017616_624449.0877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118616_624415.6666666666667646.3333333333334Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119616_6240914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119616_624449.0914.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421616_624449.0877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117616_6240877.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017616_624467.0895.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917616_624449.0920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120616_6240920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118616_6240646.3333333333334Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118616_6240646.3333333333334Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118616_6240646.3333333333334Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120616_6240920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120616_6240920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118616_6240646.3333333333334Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120616_6240920.0Nucleotide bindingATP
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119192_3670914.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117192_3670877.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120192_3670920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118192_3670646.3333333333334RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118192_3670646.3333333333334RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118192_3670646.3333333333334RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120192_3670920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120192_3670920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118192_3670646.3333333333334RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120192_3670920.0RegionNote=DS-like domain
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+11921_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000324771+1220439_913449.0914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000376567+916439_913449.0877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000376568+1018439_913449.0914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000376569+1118439_913449.0877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000376570+1219439_913449.0877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000376575+1220439_913449.0920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+12021_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+11621_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+11721_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+11921_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+11621_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+11721_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+11921_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+11921_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+12021_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+12021_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+11721_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000418800+1017439_913449.0877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+11621_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+11921_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+11921_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+11921_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+12021_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118439_913415.6666666666667646.3333333333334Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+11921_4170914.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119439_9130914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000452441+1119439_913449.0914.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+11621_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000454612+1421439_913449.0877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+11721_4170877.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117439_9130877.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000508312+1017439_913467.0895.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000513240+917439_913449.0920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+12021_4170920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120439_9130920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+11821_4170646.3333333333334Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118439_9130646.3333333333334Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+11821_4170646.3333333333334Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118439_9130646.3333333333334Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+11821_4170646.3333333333334Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118439_9130646.3333333333334Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+12021_4170920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120439_9130920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+12021_4170920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120439_9130920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+11821_4170646.3333333333334Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118439_9130646.3333333333334Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+12021_4170920.0Topological domainExtracellular
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120439_9130920.0Topological domainCytoplasmic
HgeneDDR1chr6:30861200chr11:77070062ENST00000259875+119418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000383377+120418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400410+116418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400411+117418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400414+119418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400486+116418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400488+117418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400489+119418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400491+119418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000400492+120418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000412329+120418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000415092+117418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000419412+116418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000421229+119418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000427053+119418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000429699+119418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000430933+120418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000446312+1118418_438415.6666666666667646.3333333333334TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000449518+119418_4380914.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000453510+116418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000454774+117418_4380877.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000548133+120418_4380920.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000548962+118418_4380646.3333333333334TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000549026+118418_4380646.3333333333334TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000550384+118418_4380646.3333333333334TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000550395+120418_4380920.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000552068+120418_4380920.0TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000552721+118418_4380646.3333333333334TransmembraneHelical
HgeneDDR1chr6:30861200chr11:77070062ENST00000553015+120418_4380920.0TransmembraneHelical
TgenePAK1chr6:30861200chr11:77070062ENST0000027856841675_88159.0554.0DomainCRIB
TgenePAK1chr6:30861200chr11:77070062ENST0000035634141575_88159.0546.0DomainCRIB
TgenePAK1chr6:30861200chr11:77070062ENST0000027856841670_140159.0554.0RegionNote=Autoregulatory region
TgenePAK1chr6:30861200chr11:77070062ENST0000027856841675_105159.0554.0RegionNote=GTPase-binding
TgenePAK1chr6:30861200chr11:77070062ENST0000035634141570_140159.0546.0RegionNote=Autoregulatory region
TgenePAK1chr6:30861200chr11:77070062ENST0000035634141575_105159.0546.0RegionNote=GTPase-binding


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
DDR1
PAK1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePAK1chr6:30861200chr11:77070062ENST00000278568416132_270159.0554.0CRIPAK
TgenePAK1chr6:30861200chr11:77070062ENST00000356341415132_270159.0546.0CRIPAK


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Related Drugs to DDR1-PAK1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to DDR1-PAK1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource