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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:DNAJC11-CAMTA1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: DNAJC11-CAMTA1
FusionPDB ID: 23450
FusionGDB2.0 ID: 23450
HgeneTgene
Gene symbol

DNAJC11

CAMTA1

Gene ID

55735

23261

Gene nameDnaJ heat shock protein family (Hsp40) member C11calmodulin binding transcription activator 1
SynonymsdJ126A5.1CANPMR
Cytomap

1p36.31

1p36.31-p36.23

Type of geneprotein-codingprotein-coding
DescriptiondnaJ homolog subfamily C member 11DnaJ (Hsp40) homolog, subfamily C, member 11novel DnaJ domain-containing proteincalmodulin-binding transcription activator 1
Modification date2020032720200315
UniProtAcc

Q9NVH1

Q9Y6Y1

Ensembl transtripts involved in fusion geneENST idsENST00000294401, ENST00000377577, 
ENST00000377573, ENST00000349363, 
ENST00000465508, ENST00000542246, 
ENST00000467404, ENST00000473578, 
ENST00000476163, ENST00000476864, 
ENST00000557126, ENST00000303635, 
ENST00000439411, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score5 X 5 X 5=12521 X 19 X 8=3192
# samples 524
** MAII scorelog2(5/125*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/3192*10)=-3.73335434061383
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: DNAJC11 [Title/Abstract] AND CAMTA1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)DNAJC11(6761789)-CAMTA1(6880241), # samples:1
Anticipated loss of major functional domain due to fusion event.DNAJC11-CAMTA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC11-CAMTA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC11-CAMTA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC11-CAMTA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DNAJC11 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CAMTA1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-16-1045-01BDNAJC11chr1

6761789

-CAMTA1chr1

6880241

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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377577DNAJC11chr16761789-ENST00000303635CAMTA1chr16880241+838819612451721682
ENST00000377577DNAJC11chr16761789-ENST00000439411CAMTA1chr16880241+513119612451301669
ENST00000294401DNAJC11chr16761789-ENST00000303635CAMTA1chr16880241+838819612451721682
ENST00000294401DNAJC11chr16761789-ENST00000439411CAMTA1chr16880241+513119612451301669

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377577ENST00000303635DNAJC11chr16761789-CAMTA1chr16880241+0.0003688690.99963117
ENST00000377577ENST00000439411DNAJC11chr16761789-CAMTA1chr16880241+0.0035762190.9964238
ENST00000294401ENST00000303635DNAJC11chr16761789-CAMTA1chr16880241+0.0003688690.99963117
ENST00000294401ENST00000439411DNAJC11chr16761789-CAMTA1chr16880241+0.0035762190.9964238

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>23450_23450_1_DNAJC11-CAMTA1_DNAJC11_chr1_6761789_ENST00000294401_CAMTA1_chr1_6880241_ENST00000303635_length(amino acids)=1682AA_BP=24
MATALSEEELDNEDYYSLLNVRRESVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIA
AYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQN
PDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHN
CLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSHSEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEV
PDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHK
FAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE
IKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDA
SKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQ
ACSSEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQLVSGDST
ALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLI
TGPWQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILE
RLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHL
AAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAE
CLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPE
YFQTRQEKLLPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGKWNSKDLYIGVSTVQVTGNPKG
TSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDSAENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPA
TISSTMSWLASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQ
RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCG

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>23450_23450_2_DNAJC11-CAMTA1_DNAJC11_chr1_6761789_ENST00000294401_CAMTA1_chr1_6880241_ENST00000439411_length(amino acids)=1669AA_BP=24
MATALSEEELDNEDYYSLLNVRRESVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIA
AYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQN
PDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHN
CLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSHSEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEV
PDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHK
FAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE
IKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDA
SKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQ
ACSSEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQLVSGDST
ALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLI
TGPWQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILE
RLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHL
AAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAE
CLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPE
YFQTRQEKLLPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGKWNSKDLYIGVSTVQVTGNPKG
TSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDSAENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPA
TISSTMSWLASYLADADCLPSAAQIRLSPVGSPVSEIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAF
RKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQ

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>23450_23450_3_DNAJC11-CAMTA1_DNAJC11_chr1_6761789_ENST00000377577_CAMTA1_chr1_6880241_ENST00000303635_length(amino acids)=1682AA_BP=24
MATALSEEELDNEDYYSLLNVRRESVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIA
AYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQN
PDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHN
CLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSHSEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEV
PDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHK
FAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE
IKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDA
SKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQ
ACSSEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQLVSGDST
ALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLI
TGPWQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILE
RLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHL
AAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAE
CLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPE
YFQTRQEKLLPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGKWNSKDLYIGVSTVQVTGNPKG
TSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDSAENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPA
TISSTMSWLASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQ
RELYEAARLVQTAFRKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCG

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>23450_23450_4_DNAJC11-CAMTA1_DNAJC11_chr1_6761789_ENST00000377577_CAMTA1_chr1_6880241_ENST00000439411_length(amino acids)=1669AA_BP=24
MATALSEEELDNEDYYSLLNVRRESVSQSVFCGTSTYCVLNTVPPIEDDHGNSNSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIA
AYLITFEKHEEWLTTSPKTRPQNGSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRRCYWLLQN
PDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHGIKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHN
CLCTGSLGAGGSVHHKCNSAKHRIISPKVEPRTGGYGSHSEVQHNDVSEGKHEHSHSKGSSREKRNGKVAKPVLLHQSSTEVSSTNQVEV
PDTTQSSPVSISSGLNSDPDMVDSPVVTGVSGMAVASVMGSLSQSATVFMSEVTNEAVYTMSPTAGPNHHLLSPDASQGLVLAVSSDGHK
FAFPTTGSSESLSMLPTNVSEELVLSTTLDGGRKIPETTMNFDPDCFLNNPKQGQTYGGGGLKAEMVSSNIRHSPPGERSFSFTTVLTKE
IKTEDTSFEQQMAKEAYSSSAAAVAASSLTLTAGSSLLPSGGGLSPSTTLEQMDFSAIDSNKDYTSSFSQTGHSPHIHQTPSPSFFLQDA
SKPLPVEQNTHSSLSDSGGTFVMPTVKTEASSQTSSCSGHVETRIESTSSLHLMQFQANFQAMTAEGEVTMETSQAAEGSEVLLKSGELQ
ACSSEHYLQPETNGVIRSAGGVPILPGNVVQGLYPVAQPSLGNASNMELSLDHFDISFSNQFSDLINDFISVEGGSSTIYGHQLVSGDST
ALSQSEDGARAPFTQAEMCLPCCSPQQGSLQLSSSEGGASTMAYMHVAEVVSAASAQGTLGMLQQSGRVFMVTDYSPEWSYPEGGVKVLI
TGPWQEASNNYSCLFDQISVPASLIQPGVLRCYCPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILE
RLEQMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEKMMSRACWAKSKHLIHSKTFRGMTLLHL
AAAQGYATLIQTLIKWRTKHADSIDLELEVDPLNVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAE
CLEHLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSPEIPKGVTVIASTNPELRRPRSEPSNYYSSESHKDYPAPKKHKLNPE
YFQTRQEKLLPTALSLEEPNIRKQSPSSKQSVPETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGKWNSKDLYIGVSTVQVTGNPKG
TSVGKEAAPSQVRPREPMSVLMMANREVVNTELGSYRDSAENEECGQPMDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGLERTDPA
TISSTMSWLASYLADADCLPSAAQIRLSPVGSPVSEIAFEKPNLPSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAF
RKYKGRPLREQQEVAAAVIQRCYRKYKQYALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAAVLIQKYYRSYKKCGKRRQARRTAVIVQQ

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:6761789/chr1:6880241)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DNAJC11

Q9NVH1

CAMTA1

Q9Y6Y1

FUNCTION: [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex. {ECO:0000269|PubMed:25111180, ECO:0000305}.FUNCTION: Transcriptional activator. May act as a tumor suppressor. {ECO:0000269|PubMed:11925432, ECO:0000269|PubMed:15709179}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231038_104115.01674.0Compositional biasNote=Poly-Val
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000303635023499_50215.01674.0Compositional biasNote=Poly-Gly
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221038_104115.01660.0Compositional biasNote=Poly-Val
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000439411022499_50215.01660.0Compositional biasNote=Poly-Gly
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041038_104115.081.0Compositional biasNote=Poly-Val
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047357804499_50215.081.0Compositional biasNote=Poly-Gly
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061038_10410.0238.0Compositional biasNote=Poly-Val
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047686406499_5020.0238.0Compositional biasNote=Poly-Gly
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041038_104115.0102.0Compositional biasNote=Poly-Val
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000055712604499_50215.0102.0Compositional biasNote=Poly-Gly
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000030363502363_18815.01674.0DNA bindingCG-1
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000043941102263_18815.01660.0DNA bindingCG-1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004735780463_18815.081.0DNA bindingCG-1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004768640663_1880.0238.0DNA bindingCG-1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000005571260463_18815.0102.0DNA bindingCG-1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231547_157615.01674.0DomainIQ 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231577_159915.01674.0DomainIQ 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231600_162215.01674.0DomainIQ 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000303635023873_95315.01674.0DomainNote=IPT/TIG
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221547_157615.01660.0DomainIQ 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221577_159915.01660.0DomainIQ 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221600_162215.01660.0DomainIQ 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000439411022873_95315.01660.0DomainNote=IPT/TIG
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041547_157615.081.0DomainIQ 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041577_159915.081.0DomainIQ 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041600_162215.081.0DomainIQ 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047357804873_95315.081.0DomainNote=IPT/TIG
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061547_15760.0238.0DomainIQ 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061577_15990.0238.0DomainIQ 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061600_16220.0238.0DomainIQ 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047686406873_9530.0238.0DomainNote=IPT/TIG
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041547_157615.0102.0DomainIQ 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041577_159915.0102.0DomainIQ 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041600_162215.0102.0DomainIQ 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000055712604873_95315.0102.0DomainNote=IPT/TIG
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000303635023112_11915.01674.0MotifNuclear localization signal
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000439411022112_11915.01660.0MotifNuclear localization signal
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047357804112_11915.081.0MotifNuclear localization signal
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000047686406112_1190.0238.0MotifNuclear localization signal
TgeneCAMTA1chr1:6761789chr1:6880241ENST0000055712604112_11915.0102.0MotifNuclear localization signal
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231064_109315.01674.0RepeatNote=ANK 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231109_112915.01674.0RepeatNote=ANK 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST000003036350231143_117215.01674.0RepeatNote=ANK 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221064_109315.01660.0RepeatNote=ANK 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221109_112915.01660.0RepeatNote=ANK 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST000004394110221143_117215.01660.0RepeatNote=ANK 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041064_109315.081.0RepeatNote=ANK 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041109_112915.081.0RepeatNote=ANK 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000473578041143_117215.081.0RepeatNote=ANK 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061064_10930.0238.0RepeatNote=ANK 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061109_11290.0238.0RepeatNote=ANK 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000476864061143_11720.0238.0RepeatNote=ANK 3
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041064_109315.0102.0RepeatNote=ANK 1
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041109_112915.0102.0RepeatNote=ANK 2
TgeneCAMTA1chr1:6761789chr1:6880241ENST00000557126041143_117215.0102.0RepeatNote=ANK 3

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNAJC11chr1:6761789chr1:6880241ENST00000294401-115417_45724.0508.0Coiled coilOntology_term=ECO:0000255
HgeneDNAJC11chr1:6761789chr1:6880241ENST00000377577-116417_45724.0560.0Coiled coilOntology_term=ECO:0000255
HgeneDNAJC11chr1:6761789chr1:6880241ENST00000294401-11514_8224.0508.0DomainJ
HgeneDNAJC11chr1:6761789chr1:6880241ENST00000377577-11614_8224.0560.0DomainJ


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
DNAJC11
CAMTA1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to DNAJC11-CAMTA1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to DNAJC11-CAMTA1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource