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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:FLNC-FLNB

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: FLNC-FLNB
FusionPDB ID: 30672
FusionGDB2.0 ID: 30672
HgeneTgene
Gene symbol

FLNC

FLNB

Gene ID

2318

2317

Gene namefilamin Cfilamin B
SynonymsABP-280|ABP280A|ABPA|ABPL|CMH26|FLN2|MFM5|MPD4|RCM5ABP-278|ABP-280|AOI|FH1|FLN-B|FLN1L|LRS1|SCT|TABP|TAP
Cytomap

7q32.1

3p14.3

Type of geneprotein-codingprotein-coding
Descriptionfilamin-CABP-280-like proteinABP-L, gamma filaminactin binding protein 280filamin C, gammafilamin-2gamma filaminfilamin-BABP-280 homologLarsen syndrome 1 (autosomal dominant)actin binding protein 278actin-binding-like proteinbeta-filaminfilamin B, betafilamin homolog 1filamin-3thyroid autoantigen
Modification date2020032820200313
UniProtAcc

Q14315

O75369

Ensembl transtripts involved in fusion geneENST idsENST00000325888, ENST00000346177, 
ENST00000484981, ENST00000295956, 
ENST00000348383, ENST00000357272, 
ENST00000358537, ENST00000419752, 
ENST00000429972, ENST00000490882, 
ENST00000493452, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score3 X 3 X 2=1819 X 22 X 8=3344
# samples 323
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(23/3344*10)=-3.86186908113651
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: FLNC [Title/Abstract] AND FLNB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)FLNC(128491682)-FLNB(58133932), # samples:3
Anticipated loss of major functional domain due to fusion event.FLNC-FLNB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FLNC-FLNB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FLNC-FLNB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FLNC-FLNB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FLNC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FLNB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NFLNCchr7

128491682

+FLNBchr3

58133932

+
ChimerDB4Non-CancerTCGA-L5-A4OG-11AFLNCchr7

128491682

+FLNBchr3

58133932

+
ChimerDB4Non-CancerTCGA-L5-A4OM-11AFLNCchr7

128491682

+FLNBchr3

58133932

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325888FLNCchr7128491682+ENST00000490882FLNBchr358133932+8196610326181832640
ENST00000325888FLNCchr7128491682+ENST00000429972FLNBchr358133932+9673610326181832640
ENST00000325888FLNCchr7128491682+ENST00000295956FLNBchr358133932+9673610326181832640
ENST00000325888FLNCchr7128491682+ENST00000358537FLNBchr358133932+9673610326181832640
ENST00000325888FLNCchr7128491682+ENST00000357272FLNBchr358133932+9747610326168272188
ENST00000325888FLNCchr7128491682+ENST00000348383FLNBchr358133932+9554610326180602599
ENST00000325888FLNCchr7128491682+ENST00000493452FLNBchr358133932+8199610326181832640
ENST00000325888FLNCchr7128491682+ENST00000419752FLNBchr358133932+9677610326181832640
ENST00000346177FLNCchr7128491682+ENST00000490882FLNBchr358133932+8048595521280352607
ENST00000346177FLNCchr7128491682+ENST00000429972FLNBchr358133932+9525595521280352607
ENST00000346177FLNCchr7128491682+ENST00000295956FLNBchr358133932+9525595521280352607
ENST00000346177FLNCchr7128491682+ENST00000358537FLNBchr358133932+9525595521280352607
ENST00000346177FLNCchr7128491682+ENST00000357272FLNBchr358133932+9599595521266792155
ENST00000346177FLNCchr7128491682+ENST00000348383FLNBchr358133932+9406595521279122566
ENST00000346177FLNCchr7128491682+ENST00000493452FLNBchr358133932+8051595521280352607
ENST00000346177FLNCchr7128491682+ENST00000419752FLNBchr358133932+9529595521280352607

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325888ENST00000490882FLNCchr7128491682+FLNBchr358133932+0.0006915230.99930847
ENST00000325888ENST00000429972FLNCchr7128491682+FLNBchr358133932+0.0004581090.9995419
ENST00000325888ENST00000295956FLNCchr7128491682+FLNBchr358133932+0.0004581090.9995419
ENST00000325888ENST00000358537FLNCchr7128491682+FLNBchr358133932+0.0004581090.9995419
ENST00000325888ENST00000357272FLNCchr7128491682+FLNBchr358133932+0.000581850.99941814
ENST00000325888ENST00000348383FLNCchr7128491682+FLNBchr358133932+0.000696990.999303
ENST00000325888ENST00000493452FLNCchr7128491682+FLNBchr358133932+0.0006911970.9993088
ENST00000325888ENST00000419752FLNCchr7128491682+FLNBchr358133932+0.0004577130.99954236
ENST00000346177ENST00000490882FLNCchr7128491682+FLNBchr358133932+0.0010695420.9989304
ENST00000346177ENST00000429972FLNCchr7128491682+FLNBchr358133932+0.0007527270.9992473
ENST00000346177ENST00000295956FLNCchr7128491682+FLNBchr358133932+0.0007527270.9992473
ENST00000346177ENST00000358537FLNCchr7128491682+FLNBchr358133932+0.0007527270.9992473
ENST00000346177ENST00000357272FLNCchr7128491682+FLNBchr358133932+0.0008496230.9991504
ENST00000346177ENST00000348383FLNCchr7128491682+FLNBchr358133932+0.0005169360.999483
ENST00000346177ENST00000493452FLNCchr7128491682+FLNBchr358133932+0.0010695960.9989304
ENST00000346177ENST00000419752FLNCchr7128491682+FLNBchr358133932+0.0007527750.9992473

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>30672_30672_1_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000295956_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_2_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000348383_length(amino acids)=2599AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMG
VHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYI
AQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKY
AVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQE
TPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLS

--------------------------------------------------------------

>30672_30672_3_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000357272_length(amino acids)=2188AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP

--------------------------------------------------------------

>30672_30672_4_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000358537_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_5_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000419752_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_6_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000429972_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_7_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000490882_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_8_FLNC-FLNB_FLNC_chr7_128491682_ENST00000325888_FLNB_chr3_58133932_ENST00000493452_length(amino acids)=2640AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLACDPLPHEEEPSEVPQLRQPYAPPRPGARPTHWATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTG
EVRMPSGKTARPNITDNKDGTITVRYAPTEKGLHQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEG
GLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAPGDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASI
KAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGY
GGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIP
EINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPA
EFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKV
NQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGT
GLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSA
NETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVT

--------------------------------------------------------------

>30672_30672_9_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000295956_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

>30672_30672_10_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000348383_length(amino acids)=2566AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKV
RAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDD
ARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVG
EPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSP
FKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGAGLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPC

--------------------------------------------------------------

>30672_30672_11_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000357272_length(amino acids)=2155AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV

--------------------------------------------------------------

>30672_30672_12_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000358537_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

>30672_30672_13_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000419752_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

>30672_30672_14_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000429972_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

>30672_30672_15_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000490882_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

>30672_30672_16_FLNC-FLNB_FLNC_chr7_128491682_ENST00000346177_FLNB_chr3_58133932_ENST00000493452_length(amino acids)=2607AA_BP=1352
MMNNSGYSDAGLGLGDETDEMPSTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVGKRLTDLQRDLSDGLRLIALLEVLSQKRMYRKFHPRP
NFRQMKLENVSVALEFLEREHIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMWEDEDDEDARKQTPKQRLLGWIQNKVPQLPITN
FNRDWQDGKALGALVDNCAPGLCPDWEAWDPNQPVENAREAMQQADDWLGVPQVIAPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPVRS
KQLNPKKAIAYGPGIEPQGNTVLQPAHFTVQTVDAGVGEVLVYIEDPEGHTEEAKVVPNNDKDRTYAVSYVPKVAGLHKVTVLFAGQNIE
RSPFEVNVGMALGDANKVSARGPGLEPVGNVANKPTYFDIYTAGAGTGDVAVVIVDPQGRRDTVEVALEDKGDSTFRCTYRPAMEGPHTV
HVAFAGAPITRSPFPVHVSEACNPNACRASGRGLQPKGVRVKEVADFKVFTKGAGSGELKVTVKGPKGTEEPVKVREAGDGVFECEYYPV
VPGKYVVTITWGGYAIPRSPFEVQVSPEAGVQKVRAWGPGLETGQVGKSADFVVEAIGTEVGTLGFSIEGPSQAKIECDDKGDGSCDVRY
WPTEPGEYAVHVICDDEDIRDSPFIAHILPAPPDCFPDKVKAFGPGLEPTGCIVDKPAEFTIDARAAGKGDLKLYAQDADGCPIDIKVIP
NGDGTFRCSYVPTKPIKHTIIISWGGVNVPKSPFRVNVGEGSHPERVKVYGPGVEKTGLKANEPTYFTVDCSEAGQGDVSIGIKCAPGVV
GPAEADIDFDIIKNDNDTFTVKYTPPGAGRYTIMVLFANQEIPASPFHIKVDPSHDASKVKAEGPGLNRTGVEVGKPTHFTVLTKGAGKA
KLDVQFAGTAKGEVVRDFEIIDNHDYSYTVKYTAVQQGNMAVTVTYGGDPVPKSPFVVNVAPPLDLSKIKVQGLNSKVAVGQEQAFSVNT
RGAGGQGQLDVRMTSPSRRPIPCKLEPGGGAEAQAVRYMPPEEGPYKVDITYDGHPVPGSPFAVEGVLPPDPSKVCAYGPGLKGGLVGTP
APFSIDTKGAGTGGLGLTVEGPCEAKIECQDNGDGSCAVSYLPTEPGEYTINILFAEAHIPGSPFKATIRPVFDPSKVRASGPGLERGKV
GEAATFTVDCSEAGEAELTIEILSDAGVKAEVLIHNNADGTYHITYSPAFPGTYTITIKYGGHPVPKFPTRVHVQPAVDTSGVKVSGPGV
EPHGVLREVTTEFTVDARSLTATGGNHVTARVLNPSGAKTDTYVTDNGDGTYRVQYTAYEEGVHLVEVLYDEVAVPKSPFRVGVTEGCDP
TRVRAFGPGLEGGLVNKANRFTVETRGAGTGGLGLAIEGPSEAKMSCKDNKDGSCTVEYIPFTPGDYDVNITFGGRPIPGSPFRVPVKDV
VDPGKVKCSGPGLGAGVRARVPQTFTVDCSQAGRAPLQVAVLGPTGVAEPVEVRDNGDGTHTVHYTPATDGPYTVAVKYADQEVPRSPFK
IKVLPAHDASKVRASGPGLNASGIPASLPVEFTIDARDAGEGLLTVQILDPEGKPKKANIRDNGDGTYTVSYLPDMSGRYTITIKYGGDE
IPYSPFRIHALPTGDASKCLVTVSIGGHGLGACLGPRIQIGQETVITVDAKAAGEGKVTCTVSTPDGAELDVDVVENHDGTFDIYYTAPE
PGKYVITIRFGGEHIPNSPFHVLATEEPVVPVEPMESMLRPFNLVIPFAVQKGELTGEVRMPSGKTARPNITDNKDGTITVRYAPTEKGL
HQMGIKYDGNHIPGSPLQFYVDAINSRHVSAYGPGLSHGMVNKPATFTIVTKDAGEGGLSLAVEGPSKAEITCKDNKDGTCTVSYLPTAP
GDYSIIVRFDDKHIPGSPFTAKITDDSRRCSQVKLGSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHL
VSIKKNGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVEGPSKVDIQTEDLEDGTCKVSYFPTV
PGVYIVSTKFADEHVPGSPFTVKISGEGRVKESITRTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCV
RFVPQEMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTREAGAGGLSIAVEGPSKAEITFDDHKN
GSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPVIAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHV
SELEPDKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTGIQSEFFINTTRAGPGTLSVTIEGPS
KVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPNHIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKV

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:128491682/chr3:58133932)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
FLNC

Q14315

FLNB

O75369

FUNCTION: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.FUNCTION: Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548159_2621947.33333333333332726.0DomainCalponin-homology (CH) 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+354836_1421947.33333333333332726.0DomainCalponin-homology (CH) 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447159_2621914.33333333333332693.0DomainCalponin-homology (CH) 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+344736_1421914.33333333333332693.0DomainCalponin-homology (CH) 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481735_17581947.33333333333332726.0RegionNote=Hinge 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481_2591947.33333333333332726.0RegionNote=Actin-binding
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471735_17581914.33333333333332693.0RegionNote=Hinge 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471_2591914.33333333333332693.0RegionNote=Actin-binding
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481057_11491947.33333333333332726.0RepeatNote=Filamin 9
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481150_12441947.33333333333332726.0RepeatNote=Filamin 10
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481245_13441947.33333333333332726.0RepeatNote=Filamin 11
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481345_14371947.33333333333332726.0RepeatNote=Filamin 12
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481438_15331947.33333333333332726.0RepeatNote=Filamin 13
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481534_16301947.33333333333332726.0RepeatNote=Filamin 14
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481635_17341947.33333333333332726.0RepeatNote=Filamin 15
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481759_18531947.33333333333332726.0RepeatNote=Filamin 16
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481854_19461947.33333333333332726.0RepeatNote=Filamin 17
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548270_3681947.33333333333332726.0RepeatNote=Filamin 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548370_4681947.33333333333332726.0RepeatNote=Filamin 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548469_5651947.33333333333332726.0RepeatNote=Filamin 3
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548566_6581947.33333333333332726.0RepeatNote=Filamin 4
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548662_7581947.33333333333332726.0RepeatNote=Filamin 5
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548759_8611947.33333333333332726.0RepeatNote=Filamin 6
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548862_9601947.33333333333332726.0RepeatNote=Filamin 7
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+3548961_10561947.33333333333332726.0RepeatNote=Filamin 8
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471057_11491914.33333333333332693.0RepeatNote=Filamin 9
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471150_12441914.33333333333332693.0RepeatNote=Filamin 10
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471245_13441914.33333333333332693.0RepeatNote=Filamin 11
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471345_14371914.33333333333332693.0RepeatNote=Filamin 12
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471438_15331914.33333333333332693.0RepeatNote=Filamin 13
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471534_16301914.33333333333332693.0RepeatNote=Filamin 14
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471635_17341914.33333333333332693.0RepeatNote=Filamin 15
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471759_18531914.33333333333332693.0RepeatNote=Filamin 16
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447270_3681914.33333333333332693.0RepeatNote=Filamin 1
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447370_4681914.33333333333332693.0RepeatNote=Filamin 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447469_5651914.33333333333332693.0RepeatNote=Filamin 3
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447566_6581914.33333333333332693.0RepeatNote=Filamin 4
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447662_7581914.33333333333332693.0RepeatNote=Filamin 5
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447759_8611914.33333333333332693.0RepeatNote=Filamin 6
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447862_9601914.33333333333332693.0RepeatNote=Filamin 7
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+3447961_10561914.33333333333332693.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462472_25061909.33333333333332603.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462472_26021909.33333333333332603.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452472_25061909.33333333333332562.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452472_26021909.33333333333332562.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472472_25061909.33333333333332603.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472472_26021909.33333333333332603.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452472_25061885.33333333333332579.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452472_26021885.33333333333332579.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452472_25061729.33333333333332423.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452472_26021729.33333333333332423.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462472_25061898.33333333333332592.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462472_26021898.33333333333332592.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472472_25061940.33333333333332634.0RegionHinge 2
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472472_26021940.33333333333332634.0RegionSelf-association site%2C tail
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461919_19941909.33333333333332603.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461997_20891909.33333333333332603.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462091_21851909.33333333333332603.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462188_22801909.33333333333332603.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462282_23751909.33333333333332603.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462379_24711909.33333333333332603.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633462507_26011909.33333333333332603.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451919_19941909.33333333333332562.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451997_20891909.33333333333332562.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452091_21851909.33333333333332562.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452188_22801909.33333333333332562.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452282_23751909.33333333333332562.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452379_24711909.33333333333332562.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333452507_26011909.33333333333332562.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471919_19941909.33333333333332603.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471997_20891909.33333333333332603.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472091_21851909.33333333333332603.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472188_22801909.33333333333332603.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472282_23751909.33333333333332603.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472379_24711909.33333333333332603.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233472507_26011909.33333333333332603.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451919_19941885.33333333333332579.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451997_20891885.33333333333332579.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452091_21851885.33333333333332579.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452188_22801885.33333333333332579.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452282_23751885.33333333333332579.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452379_24711885.33333333333332579.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732452507_26011885.33333333333332579.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451729_18131729.33333333333332423.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451816_19081729.33333333333332423.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451919_19941729.33333333333332423.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451997_20891729.33333333333332423.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452091_21851729.33333333333332423.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452188_22801729.33333333333332423.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452282_23751729.33333333333332423.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452379_24711729.33333333333332423.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232452507_26011729.33333333333332423.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461919_19941898.33333333333332592.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461997_20891898.33333333333332592.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462091_21851898.33333333333332592.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462188_22801898.33333333333332592.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462282_23751898.33333333333332592.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462379_24711898.33333333333332592.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233462507_26011898.33333333333332592.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471997_20891940.33333333333332634.0RepeatNote=Filamin 19
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472091_21851940.33333333333332634.0RepeatNote=Filamin 20
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472188_22801940.33333333333332634.0RepeatNote=Filamin 21
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472282_23751940.33333333333332634.0RepeatNote=Filamin 22
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472379_24711940.33333333333332634.0RepeatNote=Filamin 23
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234472507_26011940.33333333333332634.0RepeatNote=Filamin 24

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482162_22431947.33333333333332726.0RegionNote=Intradomain insert%3B mediate targeting to Z lines
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482593_26291947.33333333333332726.0RegionNote=Hinge 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482593_27251947.33333333333332726.0RegionSelf-association site%2C tail
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472162_22431914.33333333333332693.0RegionNote=Intradomain insert%3B mediate targeting to Z lines
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472593_26291914.33333333333332693.0RegionNote=Hinge 2
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472593_27251914.33333333333332693.0RegionSelf-association site%2C tail
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35481947_20331947.33333333333332726.0RepeatNote=Filamin 18
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482036_21281947.33333333333332726.0RepeatNote=Filamin 19
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482309_24011947.33333333333332726.0RepeatNote=Filamin 21
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482403_24961947.33333333333332726.0RepeatNote=Filamin 22
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482500_25921947.33333333333332726.0RepeatNote=Filamin 23
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482630_27241947.33333333333332726.0RepeatNote=Filamin 24
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471854_19461914.33333333333332693.0RepeatNote=Filamin 17
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34471947_20331914.33333333333332693.0RepeatNote=Filamin 18
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472036_21281914.33333333333332693.0RepeatNote=Filamin 19
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472309_24011914.33333333333332693.0RepeatNote=Filamin 21
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472403_24961914.33333333333332693.0RepeatNote=Filamin 22
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472500_25921914.33333333333332693.0RepeatNote=Filamin 23
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472630_27241914.33333333333332693.0RepeatNote=Filamin 24
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346139_2421909.33333333333332603.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000295956334616_1221909.33333333333332603.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345139_2421909.33333333333332562.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000348383334516_1221909.33333333333332562.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347139_2421909.33333333333332603.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000357272334716_1221909.33333333333332603.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245139_2421885.33333333333332579.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000358537324516_1221885.33333333333332579.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245139_2421729.33333333333332423.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000419752324516_1221729.33333333333332423.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346139_2421898.33333333333332592.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000429972334616_1221898.33333333333332592.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447139_2421940.33333333333332634.0DomainCalponin-homology (CH) 2
TgeneFLNBchr7:128491682chr3:58133932ENST00000490882344716_1221940.33333333333332634.0DomainCalponin-homology (CH) 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461705_17281909.33333333333332603.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461_2391909.33333333333332603.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451705_17281909.33333333333332562.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451_2391909.33333333333332562.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471705_17281909.33333333333332603.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471_2391909.33333333333332603.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451705_17281885.33333333333332579.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451_2391885.33333333333332579.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451705_17281729.33333333333332423.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451_2391729.33333333333332423.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461705_17281898.33333333333332592.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461_2391898.33333333333332592.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471705_17281940.33333333333332634.0RegionHinge 1
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471_2391940.33333333333332634.0RegionNote=Actin-binding
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461035_11271909.33333333333332603.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461128_12221909.33333333333332603.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461223_13221909.33333333333332603.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461323_14151909.33333333333332603.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461416_15111909.33333333333332603.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461512_16081909.33333333333332603.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461609_17041909.33333333333332603.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461729_18131909.33333333333332603.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461816_19081909.33333333333332603.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346249_3471909.33333333333332603.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346349_4461909.33333333333332603.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346447_5431909.33333333333332603.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346544_6361909.33333333333332603.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346640_7361909.33333333333332603.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346737_8391909.33333333333332603.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346840_9381909.33333333333332603.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000002959563346939_10341909.33333333333332603.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451035_11271909.33333333333332562.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451128_12221909.33333333333332562.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451223_13221909.33333333333332562.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451323_14151909.33333333333332562.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451416_15111909.33333333333332562.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451512_16081909.33333333333332562.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451609_17041909.33333333333332562.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451729_18131909.33333333333332562.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451816_19081909.33333333333332562.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345249_3471909.33333333333332562.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345349_4461909.33333333333332562.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345447_5431909.33333333333332562.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345544_6361909.33333333333332562.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345640_7361909.33333333333332562.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345737_8391909.33333333333332562.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345840_9381909.33333333333332562.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000003483833345939_10341909.33333333333332562.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471035_11271909.33333333333332603.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471128_12221909.33333333333332603.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471223_13221909.33333333333332603.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471323_14151909.33333333333332603.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471416_15111909.33333333333332603.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471512_16081909.33333333333332603.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471609_17041909.33333333333332603.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471729_18131909.33333333333332603.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471816_19081909.33333333333332603.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347249_3471909.33333333333332603.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347349_4461909.33333333333332603.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347447_5431909.33333333333332603.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347544_6361909.33333333333332603.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347640_7361909.33333333333332603.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347737_8391909.33333333333332603.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347840_9381909.33333333333332603.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000003572723347939_10341909.33333333333332603.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451035_11271885.33333333333332579.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451128_12221885.33333333333332579.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451223_13221885.33333333333332579.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451323_14151885.33333333333332579.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451416_15111885.33333333333332579.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451512_16081885.33333333333332579.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451609_17041885.33333333333332579.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451729_18131885.33333333333332579.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451816_19081885.33333333333332579.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245249_3471885.33333333333332579.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245349_4461885.33333333333332579.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245447_5431885.33333333333332579.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245544_6361885.33333333333332579.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245640_7361885.33333333333332579.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245737_8391885.33333333333332579.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245840_9381885.33333333333332579.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000003585373245939_10341885.33333333333332579.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451035_11271729.33333333333332423.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451128_12221729.33333333333332423.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451223_13221729.33333333333332423.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451323_14151729.33333333333332423.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451416_15111729.33333333333332423.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451512_16081729.33333333333332423.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451609_17041729.33333333333332423.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245249_3471729.33333333333332423.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245349_4461729.33333333333332423.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245447_5431729.33333333333332423.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245544_6361729.33333333333332423.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245640_7361729.33333333333332423.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245737_8391729.33333333333332423.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245840_9381729.33333333333332423.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000004197523245939_10341729.33333333333332423.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461035_11271898.33333333333332592.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461128_12221898.33333333333332592.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461223_13221898.33333333333332592.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461323_14151898.33333333333332592.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461416_15111898.33333333333332592.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461512_16081898.33333333333332592.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461609_17041898.33333333333332592.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461729_18131898.33333333333332592.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461816_19081898.33333333333332592.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346249_3471898.33333333333332592.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346349_4461898.33333333333332592.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346447_5431898.33333333333332592.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346544_6361898.33333333333332592.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346640_7361898.33333333333332592.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346737_8391898.33333333333332592.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346840_9381898.33333333333332592.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000004299723346939_10341898.33333333333332592.0RepeatNote=Filamin 8
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471035_11271940.33333333333332634.0RepeatNote=Filamin 9
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471128_12221940.33333333333332634.0RepeatNote=Filamin 10
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471223_13221940.33333333333332634.0RepeatNote=Filamin 11
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471323_14151940.33333333333332634.0RepeatNote=Filamin 12
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471416_15111940.33333333333332634.0RepeatNote=Filamin 13
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471512_16081940.33333333333332634.0RepeatNote=Filamin 14
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471609_17041940.33333333333332634.0RepeatNote=Filamin 15
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471729_18131940.33333333333332634.0RepeatNote=Filamin 16
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471816_19081940.33333333333332634.0RepeatNote=Filamin 17
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471919_19941940.33333333333332634.0RepeatNote=Filamin 18
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447249_3471940.33333333333332634.0RepeatNote=Filamin 1
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447349_4461940.33333333333332634.0RepeatNote=Filamin 2
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447447_5431940.33333333333332634.0RepeatNote=Filamin 3
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447544_6361940.33333333333332634.0RepeatNote=Filamin 4
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447640_7361940.33333333333332634.0RepeatNote=Filamin 5
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447737_8391940.33333333333332634.0RepeatNote=Filamin 6
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447840_9381940.33333333333332634.0RepeatNote=Filamin 7
TgeneFLNBchr7:128491682chr3:58133932ENST000004908823447939_10341940.33333333333332634.0RepeatNote=Filamin 8


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
FLNC_pLDDT.png
all structure
all structure
FLNB_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
FLNC
FLNB


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneFLNCchr7:128491682chr3:58133932ENST00000325888+35482403_27241947.33333333333332726.0INPPL1
HgeneFLNCchr7:128491682chr3:58133932ENST00000346177+34472403_27241914.33333333333332693.0INPPL1
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461128_15111909.33333333333332603.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451128_15111909.33333333333332562.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471128_15111909.33333333333332603.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451128_15111885.33333333333332579.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000041975232451128_15111729.33333333333332423.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461128_15111898.33333333333332592.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471128_15111940.33333333333332634.0FBLP1
TgeneFLNBchr7:128491682chr3:58133932ENST0000029595633461862_21481909.33333333333332603.0the cytoplasmic tail of GP1BA
TgeneFLNBchr7:128491682chr3:58133932ENST0000034838333451862_21481909.33333333333332562.0the cytoplasmic tail of GP1BA
TgeneFLNBchr7:128491682chr3:58133932ENST0000035727233471862_21481909.33333333333332603.0the cytoplasmic tail of GP1BA
TgeneFLNBchr7:128491682chr3:58133932ENST0000035853732451862_21481885.33333333333332579.0the cytoplasmic tail of GP1BA
TgeneFLNBchr7:128491682chr3:58133932ENST0000042997233461862_21481898.33333333333332592.0the cytoplasmic tail of GP1BA
TgeneFLNBchr7:128491682chr3:58133932ENST0000049088234471862_21481940.33333333333332634.0the cytoplasmic tail of GP1BA


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Related Drugs to FLNC-FLNB


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to FLNC-FLNB


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource