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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ITGA7-MIP

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ITGA7-MIP
FusionPDB ID: 40451
FusionGDB2.0 ID: 40451
HgeneTgene
Gene symbol

ITGA7

MIP

Gene ID

3679

4285

Gene nameintegrin subunit alpha 7mitochondrial intermediate peptidase
Synonyms-COXPD31|HMIP|MIP
Cytomap

12q13.2

13q12.12

Type of geneprotein-codingprotein-coding
Descriptionintegrin alpha-7integrin alpha 7 chainmitochondrial intermediate peptidase
Modification date2020032820200313
UniProtAcc

Q13683

Q8TD10

Ensembl transtripts involved in fusion geneENST idsENST00000257879, ENST00000257880, 
ENST00000347027, ENST00000394229, 
ENST00000394230, ENST00000452168, 
ENST00000553804, ENST00000555728, 
ENST00000555551, ENST00000257979, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score7 X 8 X 5=2803 X 2 X 2=12
# samples 84
** MAII scorelog2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/12*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ITGA7 [Title/Abstract] AND MIP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ITGA7(56086627)-MIP(56847539), # samples:1
ITGA7(56086628)-MIP(56847539), # samples:1
Anticipated loss of major functional domain due to fusion event.ITGA7-MIP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGA7-MIP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGA7-MIP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ITGA7-MIP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ITGA7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MIP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-1724-01AITGA7chr12

56086628

-MIPchr12

56847539

-
ChimerDB4OVTCGA-61-1724ITGA7chr12

56086627

-MIPchr12

56847539

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000553804ITGA7chr1256086627-ENST00000257979MIPchr1256847539-508528751933061095
ENST00000257879ITGA7chr1256086627-ENST00000257979MIPchr1256847539-527030607834911137
ENST00000347027ITGA7chr1256086627-ENST00000257979MIPchr1256847539-523830286434591131
ENST00000452168ITGA7chr1256086627-ENST00000257979MIPchr1256847539-491727073131381035
ENST00000394229ITGA7chr1256086627-ENST00000257979MIPchr1256847539-527430648234951137
ENST00000257880ITGA7chr1256086627-ENST00000257979MIPchr1256847539-540631968236271181
ENST00000394230ITGA7chr1256086627-ENST00000257979MIPchr1256847539-528630768235071141
ENST00000555728ITGA7chr1256086627-ENST00000257979MIPchr1256847539-521530052934361135
ENST00000553804ITGA7chr1256086628-ENST00000257979MIPchr1256847539-508528751933061095
ENST00000257879ITGA7chr1256086628-ENST00000257979MIPchr1256847539-527030607834911137
ENST00000347027ITGA7chr1256086628-ENST00000257979MIPchr1256847539-523830286434591131
ENST00000452168ITGA7chr1256086628-ENST00000257979MIPchr1256847539-491727073131381035
ENST00000394229ITGA7chr1256086628-ENST00000257979MIPchr1256847539-527430648234951137
ENST00000257880ITGA7chr1256086628-ENST00000257979MIPchr1256847539-540631968236271181
ENST00000394230ITGA7chr1256086628-ENST00000257979MIPchr1256847539-528630768235071141
ENST00000555728ITGA7chr1256086628-ENST00000257979MIPchr1256847539-521530052934361135

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000553804ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0006041540.99939585
ENST00000257879ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0009904510.9990095
ENST00000347027ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0007582960.9992417
ENST00000452168ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0004507030.9995493
ENST00000394229ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.000987020.99901295
ENST00000257880ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0007255970.99927443
ENST00000394230ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0007940830.9992059
ENST00000555728ENST00000257979ITGA7chr1256086627-MIPchr1256847539-0.0005587130.9994413
ENST00000553804ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0006041540.99939585
ENST00000257879ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0009904510.9990095
ENST00000347027ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0007582960.9992417
ENST00000452168ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0004507030.9995493
ENST00000394229ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.000987020.99901295
ENST00000257880ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0007255970.99927443
ENST00000394230ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0007940830.9992059
ENST00000555728ENST00000257979ITGA7chr1256086628-MIPchr1256847539-0.0005587130.9994413

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>40451_40451_1_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000257879_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1137AA_BP=994
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKD
KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYL
ILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKK
NITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV

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>40451_40451_2_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000257880_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1181AA_BP=1038
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
TARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG
KGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN
QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMD
GNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV
PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEI
HFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS
LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIA
GMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN
ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVAL
AVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVSNGQPEVT

--------------------------------------------------------------

>40451_40451_3_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000347027_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1131AA_BP=988
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV
VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALS
GQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG
ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAF
LNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLH
PAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGG

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>40451_40451_4_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000394229_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1137AA_BP=994
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKD
KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYL
ILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKK
NITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV

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>40451_40451_5_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000394230_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1141AA_BP=998
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
TARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVM
LSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIA
VGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDL
EQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE
NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV
DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQV
TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQG
QSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA
EKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHW

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>40451_40451_6_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000452168_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1035AA_BP=892
MGDLAGLQERGLVVVWLSSKCWPEASAQRKGALETVQMAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGKETCAHRYEARQRV
DQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH
LDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAV
ADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHG
SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLR
VCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS
LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIG
LELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETT
ELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWP
HEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVG
QATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLL

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>40451_40451_7_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000553804_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1095AA_BP=952
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG
LFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFS
IDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVY
VYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGS
LDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL
RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ
RAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM
LPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP
LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS
PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLG
SVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVSNGQ

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>40451_40451_8_ITGA7-MIP_ITGA7_chr12_56086627_ENST00000555728_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1135AA_BP=992
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG
LFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLL
FVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL
TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD
GDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA
GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKL
RAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTAL
FALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLIL
STSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTL
GSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI
TLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGP

--------------------------------------------------------------

>40451_40451_9_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000257879_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1137AA_BP=994
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKD
KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYL
ILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKK
NITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV

--------------------------------------------------------------

>40451_40451_10_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000257880_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1181AA_BP=1038
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
TARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSG
KGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLN
QGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMD
GNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQV
PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEI
HFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDS
LHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIA
GMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPN
ILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVAL
AVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVSNGQPEVT

--------------------------------------------------------------

>40451_40451_11_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000347027_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1131AA_BP=988
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV
VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALS
GQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG
ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAF
LNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLH
PAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGG

--------------------------------------------------------------

>40451_40451_12_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000394229_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1137AA_BP=994
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
LLFVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAP
FDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKD
KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYL
ILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKK
NITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWV

--------------------------------------------------------------

>40451_40451_13_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000394230_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1141AA_BP=998
MAGRTSGRRLKDQRDFGDQRRAWGDLGLGACEISLAFAGSSRRDRPMAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRK
EGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPG
GKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG
TARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVM
LSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIA
VGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDL
EQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE
NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV
DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQV
TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQG
QSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA
EKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHW

--------------------------------------------------------------

>40451_40451_14_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000452168_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1035AA_BP=892
MGDLAGLQERGLVVVWLSSKCWPEASAQRKGALETVQMAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGKETCAHRYEARQRV
DQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH
LDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAV
ADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHG
SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLR
VCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS
LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIG
LELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETT
ELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWP
HEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVG
QATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLL

--------------------------------------------------------------

>40451_40451_15_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000553804_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1095AA_BP=952
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG
LFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFS
IDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVY
VYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGS
LDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL
RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ
RAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM
LPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP
LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS
PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLG
SVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGAKPDVSNGQ

--------------------------------------------------------------

>40451_40451_16_ITGA7-MIP_ITGA7_chr12_56086628_ENST00000555728_MIP_chr12_56847539_ENST00000257979_length(amino acids)=1135AA_BP=992
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG
LFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGLL
FVTNIDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL
TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD
GDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCA
GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKL
RAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTAL
FALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLIL
STSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTL
GSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI
TLLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGP

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56086627/chr12:56847539)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITGA7

Q13683

MIP

Q8TD10

FUNCTION: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells. {ECO:0000250, ECO:0000269|PubMed:10694445, ECO:0000269|PubMed:17641293, ECO:0000269|PubMed:9307969}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125372_380948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125434_442948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125492_500948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227372_380992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227434_442992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227492_500992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125372_380855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125434_442855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125492_500855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125372_380952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125434_442952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125492_500952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226372_380992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226434_442992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226492_500992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125372_380948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125434_442948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125492_500948.01138.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227372_380992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227434_442992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227492_500992.01163.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125372_380855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125434_442855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125492_500855.01045.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125372_380952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125434_442952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125492_500952.01142.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226372_380992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226434_442992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226492_500992.01182.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227953_958992.01163.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226953_958992.01182.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227953_958992.01163.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226953_958992.01182.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125110_175948.01138.0RepeatFG-GAP 2
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125185_238948.01138.0RepeatFG-GAP 3
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125292_349948.01138.0RepeatFG-GAP 4
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125350_411948.01138.0RepeatFG-GAP 5
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-212535_103948.01138.0RepeatFG-GAP 1
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125412_467948.01138.0RepeatFG-GAP 6
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125471_530948.01138.0RepeatFG-GAP 7
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227110_175992.01163.0RepeatFG-GAP 2
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227185_238992.01163.0RepeatFG-GAP 3
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227292_349992.01163.0RepeatFG-GAP 4
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227350_411992.01163.0RepeatFG-GAP 5
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-222735_103992.01163.0RepeatFG-GAP 1
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227412_467992.01163.0RepeatFG-GAP 6
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-2227471_530992.01163.0RepeatFG-GAP 7
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125110_175855.01045.0RepeatFG-GAP 2
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125185_238855.01045.0RepeatFG-GAP 3
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125292_349855.01045.0RepeatFG-GAP 4
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125350_411855.01045.0RepeatFG-GAP 5
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-212535_103855.01045.0RepeatFG-GAP 1
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125412_467855.01045.0RepeatFG-GAP 6
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125471_530855.01045.0RepeatFG-GAP 7
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125110_175952.01142.0RepeatFG-GAP 2
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125185_238952.01142.0RepeatFG-GAP 3
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125292_349952.01142.0RepeatFG-GAP 4
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125350_411952.01142.0RepeatFG-GAP 5
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-212535_103952.01142.0RepeatFG-GAP 1
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125412_467952.01142.0RepeatFG-GAP 6
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125471_530952.01142.0RepeatFG-GAP 7
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226110_175992.01182.0RepeatFG-GAP 2
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226185_238992.01182.0RepeatFG-GAP 3
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226292_349992.01182.0RepeatFG-GAP 4
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226350_411992.01182.0RepeatFG-GAP 5
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-222635_103992.01182.0RepeatFG-GAP 1
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226412_467992.01182.0RepeatFG-GAP 6
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-2226471_530992.01182.0RepeatFG-GAP 7
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125110_175948.01138.0RepeatFG-GAP 2
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125185_238948.01138.0RepeatFG-GAP 3
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125292_349948.01138.0RepeatFG-GAP 4
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125350_411948.01138.0RepeatFG-GAP 5
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-212535_103948.01138.0RepeatFG-GAP 1
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125412_467948.01138.0RepeatFG-GAP 6
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125471_530948.01138.0RepeatFG-GAP 7
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227110_175992.01163.0RepeatFG-GAP 2
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227185_238992.01163.0RepeatFG-GAP 3
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227292_349992.01163.0RepeatFG-GAP 4
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227350_411992.01163.0RepeatFG-GAP 5
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-222735_103992.01163.0RepeatFG-GAP 1
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227412_467992.01163.0RepeatFG-GAP 6
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-2227471_530992.01163.0RepeatFG-GAP 7
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125110_175855.01045.0RepeatFG-GAP 2
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125185_238855.01045.0RepeatFG-GAP 3
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125292_349855.01045.0RepeatFG-GAP 4
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125350_411855.01045.0RepeatFG-GAP 5
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-212535_103855.01045.0RepeatFG-GAP 1
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125412_467855.01045.0RepeatFG-GAP 6
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125471_530855.01045.0RepeatFG-GAP 7
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125110_175952.01142.0RepeatFG-GAP 2
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125185_238952.01142.0RepeatFG-GAP 3
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125292_349952.01142.0RepeatFG-GAP 4
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125350_411952.01142.0RepeatFG-GAP 5
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-212535_103952.01142.0RepeatFG-GAP 1
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125412_467952.01142.0RepeatFG-GAP 6
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125471_530952.01142.0RepeatFG-GAP 7
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226110_175992.01182.0RepeatFG-GAP 2
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226185_238992.01182.0RepeatFG-GAP 3
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226292_349992.01182.0RepeatFG-GAP 4
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226350_411992.01182.0RepeatFG-GAP 5
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-222635_103992.01182.0RepeatFG-GAP 1
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226412_467992.01182.0RepeatFG-GAP 6
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-2226471_530992.01182.0RepeatFG-GAP 7
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904177_183120.0264.0IntramembraneOntology_term=ECO:0000250
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904184_194120.0264.0IntramembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904177_183120.0264.0IntramembraneOntology_term=ECO:0000250
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904184_194120.0264.0IntramembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904184_186120.0264.0MotifNote=NPA 2
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904184_186120.0264.0MotifNote=NPA 2
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904148_159120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904195_200120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904220_263120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904148_159120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904195_200120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904220_263120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904127_147120.0264.0TransmembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904160_176120.0264.0TransmembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904201_219120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904127_147120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904160_176120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904201_219120.0264.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-2125953_958948.01138.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-2125953_958855.01045.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-2125953_958952.01142.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-2125953_958948.01138.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-2125953_958855.01045.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-2125953_958952.01142.0Compositional biasNote=Poly-Arg
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251107_1111948.01138.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271107_1111992.01163.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251107_1111855.01045.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251107_1111952.01142.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261107_1111992.01182.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251107_1111948.01138.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271107_1111992.01163.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251107_1111855.01045.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251107_1111952.01142.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261107_1111992.01182.0MotifNote=GFFKR motif
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251157_1176948.01138.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271157_1176992.01163.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251157_1176855.01045.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251157_1176952.01142.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261157_1176992.01182.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251157_1176948.01138.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271157_1176992.01163.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251157_1176855.01045.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251157_1176952.01142.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261157_1176992.01182.0RegionNote=3 X 4 AA repeats of D-X-H-P
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251157_1160948.01138.0RepeatNote=1
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251165_1168948.01138.0RepeatNote=2
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251173_1176948.01138.0RepeatNote=3
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271157_1160992.01163.0RepeatNote=1
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271165_1168992.01163.0RepeatNote=2
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271173_1176992.01163.0RepeatNote=3
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251157_1160855.01045.0RepeatNote=1
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251165_1168855.01045.0RepeatNote=2
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251173_1176855.01045.0RepeatNote=3
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251157_1160952.01142.0RepeatNote=1
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251165_1168952.01142.0RepeatNote=2
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251173_1176952.01142.0RepeatNote=3
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261157_1160992.01182.0RepeatNote=1
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261165_1168992.01182.0RepeatNote=2
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261173_1176992.01182.0RepeatNote=3
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251157_1160948.01138.0RepeatNote=1
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251165_1168948.01138.0RepeatNote=2
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251173_1176948.01138.0RepeatNote=3
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271157_1160992.01163.0RepeatNote=1
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271165_1168992.01163.0RepeatNote=2
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271173_1176992.01163.0RepeatNote=3
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251157_1160855.01045.0RepeatNote=1
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251165_1168855.01045.0RepeatNote=2
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251173_1176855.01045.0RepeatNote=3
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251157_1160952.01142.0RepeatNote=1
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251165_1168952.01142.0RepeatNote=2
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251173_1176952.01142.0RepeatNote=3
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261157_1160992.01182.0RepeatNote=1
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261165_1168992.01182.0RepeatNote=2
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261173_1176992.01182.0RepeatNote=3
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251104_1181948.01138.0Topological domainCytoplasmic
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-212534_1082948.01138.0Topological domainExtracellular
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271104_1181992.01163.0Topological domainCytoplasmic
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-222734_1082992.01163.0Topological domainExtracellular
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251104_1181855.01045.0Topological domainCytoplasmic
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-212534_1082855.01045.0Topological domainExtracellular
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251104_1181952.01142.0Topological domainCytoplasmic
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-212534_1082952.01142.0Topological domainExtracellular
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261104_1181992.01182.0Topological domainCytoplasmic
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-222634_1082992.01182.0Topological domainExtracellular
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251104_1181948.01138.0Topological domainCytoplasmic
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-212534_1082948.01138.0Topological domainExtracellular
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271104_1181992.01163.0Topological domainCytoplasmic
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-222734_1082992.01163.0Topological domainExtracellular
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251104_1181855.01045.0Topological domainCytoplasmic
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-212534_1082855.01045.0Topological domainExtracellular
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251104_1181952.01142.0Topological domainCytoplasmic
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-212534_1082952.01142.0Topological domainExtracellular
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261104_1181992.01182.0Topological domainCytoplasmic
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-222634_1082992.01182.0Topological domainExtracellular
HgeneITGA7chr12:56086627chr12:56847539ENST00000257879-21251083_1103948.01138.0TransmembraneHelical
HgeneITGA7chr12:56086627chr12:56847539ENST00000257880-22271083_1103992.01163.0TransmembraneHelical
HgeneITGA7chr12:56086627chr12:56847539ENST00000452168-21251083_1103855.01045.0TransmembraneHelical
HgeneITGA7chr12:56086627chr12:56847539ENST00000553804-21251083_1103952.01142.0TransmembraneHelical
HgeneITGA7chr12:56086627chr12:56847539ENST00000555728-22261083_1103992.01182.0TransmembraneHelical
HgeneITGA7chr12:56086628chr12:56847539ENST00000257879-21251083_1103948.01138.0TransmembraneHelical
HgeneITGA7chr12:56086628chr12:56847539ENST00000257880-22271083_1103992.01163.0TransmembraneHelical
HgeneITGA7chr12:56086628chr12:56847539ENST00000452168-21251083_1103855.01045.0TransmembraneHelical
HgeneITGA7chr12:56086628chr12:56847539ENST00000553804-21251083_1103952.01142.0TransmembraneHelical
HgeneITGA7chr12:56086628chr12:56847539ENST00000555728-22261083_1103992.01182.0TransmembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST000002579790462_67120.0264.0IntramembraneOntology_term=ECO:0000250
TgeneMIPchr12:56086627chr12:56847539ENST000002579790468_78120.0264.0IntramembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST000002579790462_67120.0264.0IntramembraneOntology_term=ECO:0000250
TgeneMIPchr12:56086628chr12:56847539ENST000002579790468_78120.0264.0IntramembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST000002579790468_70120.0264.0MotifNote=NPA 1
TgeneMIPchr12:56086628chr12:56847539ENST000002579790468_70120.0264.0MotifNote=NPA 1
TgeneMIPchr12:56086627chr12:56847539ENST0000025797904108_126120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086627chr12:56847539ENST00000257979041_8120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086627chr12:56847539ENST000002579790433_38120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086627chr12:56847539ENST000002579790479_84120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086628chr12:56847539ENST0000025797904108_126120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086628chr12:56847539ENST00000257979041_8120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086628chr12:56847539ENST000002579790433_38120.0264.0Topological domainExtracellular
TgeneMIPchr12:56086628chr12:56847539ENST000002579790479_84120.0264.0Topological domainCytoplasmic
TgeneMIPchr12:56086627chr12:56847539ENST000002579790439_61120.0264.0TransmembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST000002579790485_107120.0264.0TransmembraneHelical
TgeneMIPchr12:56086627chr12:56847539ENST00000257979049_32120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST000002579790439_61120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST000002579790485_107120.0264.0TransmembraneHelical
TgeneMIPchr12:56086628chr12:56847539ENST00000257979049_32120.0264.0TransmembraneHelical


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ITGA7
MIP


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ITGA7-MIP


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ITGA7-MIP


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource