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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:KAT6B-PPP3CB

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: KAT6B-PPP3CB
	FusionPDB ID: 41239
	FusionGDB2.0 ID: 41239
		Hgene	Tgene
	Gene symbol	KAT6B	PPP3CB
	Gene ID	23522	5532
	Gene name	lysine acetyltransferase 6B	protein phosphatase 3 catalytic subunit beta
	Synonyms	GTPTS\|MORF\|MOZ2\|MYST4\|ZC2HC6B\|qkf\|querkopf	CALNA2\|CALNB\|CNA2\|PP2Bbeta
	Cytomap	10q22.2	10q22.2
	Type of gene	protein-coding	protein-coding
	Description	histone acetyltransferase KAT6BK(lysine) acetyltransferase 6BMOZ, YBF2/SAS3, SAS2 and TIP60 protein 4MOZ-related factorMYST histone acetyltransferase (monocytic leukemia) 4MYST-4histone acetyltransferase MORFhistone acetyltransferase MOZ2histone a	serine/threonine-protein phosphatase 2B catalytic subunit beta isoformCAM-PRP catalytic subunitCNA betacalcineurin A betacalcineurin A2calmodulin-dependent calcineurin A subunit beta isoformprotein phosphatase 2B, catalytic subunit, beta isoformpro
	Modification date	20200313	20200313
	UniProtAcc	Q8WYB5	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000490365, ENST00000287239, ENST00000372711, ENST00000372714, ENST00000372724, ENST00000372725,	ENST00000342558, ENST00000360663, ENST00000394822, ENST00000394828, ENST00000394829, ENST00000544628, ENST00000545874, ENST00000495897,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	23 X 21 X 10=4830	4 X 5 X 3=60
	# samples	32	5
	** MAII score	log2(32/4830*10)=-3.91587937883577 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: KAT6B [Title/Abstract] AND PPP3CB [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	KAT6B(76748870)-PPP3CB(75206331), # samples:1
Anticipated loss of major functional domain due to fusion event.	KAT6B-PPP3CB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KAT6B-PPP3CB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. KAT6B-PPP3CB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. KAT6B-PPP3CB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	KAT6B	GO:0016573	histone acetylation	11965546
Hgene	KAT6B	GO:0043966	histone H3 acetylation	16387653
Hgene	KAT6B	GO:0045892	negative regulation of transcription, DNA-templated	10497217
Hgene	KAT6B	GO:0045893	positive regulation of transcription, DNA-templated	10497217\|11965546
Tgene	PPP3CB	GO:0006470	protein dephosphorylation	19154138\|26794871
Tgene	PPP3CB	GO:0033173	calcineurin-NFAT signaling cascade	19154138\|22688515
Tgene	PPP3CB	GO:0035690	cellular response to drug	11005320
Tgene	PPP3CB	GO:0045944	positive regulation of transcription by RNA polymerase II	22688515

Fusion gene breakpoints across KAT6B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PPP3CB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	173N	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000360663	PPP3CB	chr10	75206331	-	4307	2104	342	2492	716
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000394828	PPP3CB	chr10	75206331	-	3902	2104	342	2465	707
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000394829	PPP3CB	chr10	75206331	-	3932	2104	342	2495	717
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000342558	PPP3CB	chr10	75206331	-	3229	2104	342	2408	688
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000545874	PPP3CB	chr10	75206331	-	2875	2104	342	2411	689
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000394822	PPP3CB	chr10	75206331	-	2409	2104	342	2408	688
ENST00000372725	KAT6B	chr10	76748870	+	ENST00000544628	PPP3CB	chr10	75206331	-	3496	2104	342	2492	716
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000360663	PPP3CB	chr10	75206331	-	4470	2267	505	2655	716
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000394828	PPP3CB	chr10	75206331	-	4065	2267	505	2628	707
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000394829	PPP3CB	chr10	75206331	-	4095	2267	505	2658	717
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000342558	PPP3CB	chr10	75206331	-	3392	2267	505	2571	688
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000545874	PPP3CB	chr10	75206331	-	3038	2267	505	2574	689
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000394822	PPP3CB	chr10	75206331	-	2572	2267	505	2571	689
ENST00000372724	KAT6B	chr10	76748870	+	ENST00000544628	PPP3CB	chr10	75206331	-	3659	2267	505	2655	716
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000360663	PPP3CB	chr10	75206331	-	5321	3118	480	3506	1008
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000394828	PPP3CB	chr10	75206331	-	4916	3118	480	3479	999
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000394829	PPP3CB	chr10	75206331	-	4946	3118	480	3509	1009
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000342558	PPP3CB	chr10	75206331	-	4243	3118	480	3422	980
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000545874	PPP3CB	chr10	75206331	-	3889	3118	480	3425	981
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000394822	PPP3CB	chr10	75206331	-	3423	3118	480	3422	980
ENST00000287239	KAT6B	chr10	76748870	+	ENST00000544628	PPP3CB	chr10	75206331	-	4510	3118	480	3506	1008
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000360663	PPP3CB	chr10	75206331	-	4358	2155	393	2543	716
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000394828	PPP3CB	chr10	75206331	-	3953	2155	393	2516	707
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000394829	PPP3CB	chr10	75206331	-	3983	2155	393	2546	717
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000342558	PPP3CB	chr10	75206331	-	3280	2155	393	2459	688
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000545874	PPP3CB	chr10	75206331	-	2926	2155	393	2462	689
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000394822	PPP3CB	chr10	75206331	-	2460	2155	393	2459	688
ENST00000372714	KAT6B	chr10	76748870	+	ENST00000544628	PPP3CB	chr10	75206331	-	3547	2155	393	2543	716
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000360663	PPP3CB	chr10	75206331	-	4594	2391	302	2779	825
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000394828	PPP3CB	chr10	75206331	-	4189	2391	302	2752	816
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000394829	PPP3CB	chr10	75206331	-	4219	2391	302	2782	826
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000342558	PPP3CB	chr10	75206331	-	3516	2391	302	2695	797
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000545874	PPP3CB	chr10	75206331	-	3162	2391	302	2698	798
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000394822	PPP3CB	chr10	75206331	-	2696	2391	302	2695	798
ENST00000372711	KAT6B	chr10	76748870	+	ENST00000544628	PPP3CB	chr10	75206331	-	3783	2391	302	2779	825

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000372725	ENST00000360663	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000226713	0.9997733
ENST00000372725	ENST00000394828	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000314253	0.99968576
ENST00000372725	ENST00000394829	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000314932	0.99968505
ENST00000372725	ENST00000342558	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000247824	0.9997522
ENST00000372725	ENST00000545874	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000266213	0.99973375
ENST00000372725	ENST00000394822	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000439908	0.99956006
ENST00000372725	ENST00000544628	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000280073	0.9997199
ENST00000372724	ENST00000360663	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000246311	0.99975365
ENST00000372724	ENST00000394828	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.00034225	0.99965775
ENST00000372724	ENST00000394829	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.00033975	0.99966025
ENST00000372724	ENST00000342558	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000259563	0.9997404
ENST00000372724	ENST00000545874	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000281239	0.9997187
ENST00000372724	ENST00000394822	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000491326	0.9995086
ENST00000372724	ENST00000544628	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000301141	0.9996989
ENST00000287239	ENST00000360663	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000151863	0.9998481
ENST00000287239	ENST00000394828	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000290368	0.99970967
ENST00000287239	ENST00000394829	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000269509	0.9997305
ENST00000287239	ENST00000342558	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000234298	0.9997657
ENST00000287239	ENST00000545874	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000280328	0.9997197
ENST00000287239	ENST00000394822	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000370211	0.99962974
ENST00000287239	ENST00000544628	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000183374	0.9998166
ENST00000372714	ENST00000360663	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000244665	0.9997553
ENST00000372714	ENST00000394828	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000340389	0.99965966
ENST00000372714	ENST00000394829	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000340728	0.9996593
ENST00000372714	ENST00000342558	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000257336	0.9997427
ENST00000372714	ENST00000545874	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000289018	0.999711
ENST00000372714	ENST00000394822	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000521227	0.99947876
ENST00000372714	ENST00000544628	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000307117	0.9996929
ENST00000372711	ENST00000360663	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000227333	0.9997727
ENST00000372711	ENST00000394828	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000276059	0.999724
ENST00000372711	ENST00000394829	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000280615	0.9997193
ENST00000372711	ENST00000342558	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000199063	0.999801
ENST00000372711	ENST00000545874	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000238082	0.9997619
ENST00000372711	ENST00000394822	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000274784	0.99972516
ENST00000372711	ENST00000544628	KAT6B	chr10	76748870	+	PPP3CB	chr10	75206331	-	0.000259302	0.99974066

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>41239_41239_1_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000342558_length(amino acids)=980AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMA

--------------------------------------------------------------

>41239_41239_2_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000360663_length(amino acids)=1008AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMA
RVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNS

--------------------------------------------------------------

>41239_41239_3_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000394822_length(amino acids)=980AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMA

--------------------------------------------------------------

>41239_41239_4_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000394828_length(amino acids)=999AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKM
ARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATEN

--------------------------------------------------------------

>41239_41239_5_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000394829_length(amino acids)=1009AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKM
ARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFN

--------------------------------------------------------------

>41239_41239_6_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000544628_length(amino acids)=1008AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMA
RVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNS

--------------------------------------------------------------

>41239_41239_7_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000287239_PPP3CB_chr10_75206331_ENST00000545874_length(amino acids)=981AA_BP=880
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATGTTQKLKPPPSSLPPPTPISGQSPSSQKSSTATSSPSPQSSSSQCSVPSLSSLTTN
SQLKALFDGLSHIYTTQGQSRKKGHPSYAPPKRMRRKTELSSTAKSKAHFFGKRDIRSRFISHSSSSSWGMARGSIFKAIAHFKRTTFLK
KHRMLGRLKYKVTPQMGTPSPGKGSLTDGRIKPDQDDDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCG
RYPSVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLL
AKLFLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKM

--------------------------------------------------------------

>41239_41239_8_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000342558_length(amino acids)=797AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVF

--------------------------------------------------------------

>41239_41239_9_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000360663_length(amino acids)=825AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNT

--------------------------------------------------------------

>41239_41239_10_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000394822_length(amino acids)=798AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVF

--------------------------------------------------------------

>41239_41239_11_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000394828_length(amino acids)=816AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARV
FSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGT

--------------------------------------------------------------

>41239_41239_12_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000394829_length(amino acids)=826AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARV
FSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLN

--------------------------------------------------------------

>41239_41239_13_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000544628_length(amino acids)=825AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVF
SVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNT

--------------------------------------------------------------

>41239_41239_14_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372711_PPP3CB_chr10_75206331_ENST00000545874_length(amino acids)=798AA_BP=697
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPGRGQKTKVCTTPSSGHAASGKDSSSRLAVTDPTRPGATTKITTTSTYISASTLKVNKKTKGLIDGLTKFFTPSPD
GRRSRGEIIDFSKHYRPRKKVSQKQSCTSHVLATDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYP
SVIEFGKYEIQTWYSSPYPQEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKL
FLDHKTLYYDVEPFLFYVLTKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARV

--------------------------------------------------------------

>41239_41239_15_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000342558_length(amino acids)=688AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_16_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000360663_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_17_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000394822_length(amino acids)=688AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_18_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000394828_length(amino acids)=707AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_19_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000394829_length(amino acids)=717AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_20_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000544628_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_21_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372714_PPP3CB_chr10_75206331_ENST00000545874_length(amino acids)=689AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_22_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000342558_length(amino acids)=688AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_23_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000360663_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_24_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000394822_length(amino acids)=689AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_25_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000394828_length(amino acids)=707AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_26_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000394829_length(amino acids)=717AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_27_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000544628_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_28_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372724_PPP3CB_chr10_75206331_ENST00000545874_length(amino acids)=689AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_29_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000342558_length(amino acids)=688AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_30_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000360663_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_31_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000394822_length(amino acids)=688AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_32_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000394828_length(amino acids)=707AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_33_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000394829_length(amino acids)=717AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

>41239_41239_34_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000544628_length(amino acids)=716AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPT

--------------------------------------------------------------

>41239_41239_35_KAT6B-PPP3CB_KAT6B_chr10_76748870_ENST00000372725_PPP3CB_chr10_75206331_ENST00000545874_length(amino acids)=689AA_BP=588
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFIGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTP

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:76748870/chr10:75206331)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
KAT6B Q8WYB5	.
FUNCTION: Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. {ECO:0000269\|PubMed:10497217, ECO:0000269\|PubMed:11965546, ECO:0000269\|PubMed:16387653}.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

492_533

876.3333333333334

2074.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

521_524

876.3333333333334

2074.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

599_605

876.3333333333334

2074.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

492_533

693.3333333333334

1891.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

521_524

693.3333333333334

1891.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

599_605

693.3333333333334

1891.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

492_533

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

521_524

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

492_533

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

521_524

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

492_533

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

521_524

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

103_176

876.3333333333334

2074.0

Domain

H15

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

103_176

693.3333333333334

1891.0

Domain

H15

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

103_176

584.3333333333334

1782.0

Domain

H15

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

103_176

584.3333333333334

1782.0

Domain

H15

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

103_176

584.3333333333334

1782.0

Domain

H15

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

361_717

876.3333333333334

2074.0

Region

Note=Negatively regulates HAT activity

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

856_860

876.3333333333334

2074.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

865_871

876.3333333333334

2074.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

213_272

876.3333333333334

2074.0

Zinc finger

PHD-type 1

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

269_320

876.3333333333334

2074.0

Zinc finger

PHD-type 2

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

748_773

876.3333333333334

2074.0

Zinc finger

C2HC MYST-type

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

213_272

693.3333333333334

1891.0

Zinc finger

PHD-type 1

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

269_320

693.3333333333334

1891.0

Zinc finger

PHD-type 2

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

213_272

584.3333333333334

1782.0

Zinc finger

PHD-type 1

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

269_320

584.3333333333334

1782.0

Zinc finger

PHD-type 2

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

213_272

584.3333333333334

1782.0

Zinc finger

PHD-type 1

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

269_320

584.3333333333334

1782.0

Zinc finger

PHD-type 2

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

213_272

584.3333333333334

1782.0

Zinc finger

PHD-type 1

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

269_320

584.3333333333334

1782.0

Zinc finger

PHD-type 2

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

401_415

395.3333333333333

525.0

Region

Calmodulin-binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

416_423

395.3333333333333

525.0

Region

Autoinhibitory segment

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

474_496

395.3333333333333

525.0

Region

Autoinhibitory domain

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

416_423

413.3333333333333

515.0

Region

Autoinhibitory segment

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

474_496

413.3333333333333

515.0

Region

Autoinhibitory domain

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

401_415

395.3333333333333

516.0

Region

Calmodulin-binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

416_423

395.3333333333333

516.0

Region

Autoinhibitory segment

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

474_496

395.3333333333333

516.0

Region

Autoinhibitory domain

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

401_415

395.3333333333333

526.0

Region

Calmodulin-binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

416_423

395.3333333333333

526.0

Region

Autoinhibitory segment

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

474_496

395.3333333333333

526.0

Region

Autoinhibitory domain

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1070_1104

876.3333333333334

2074.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1204_1207

876.3333333333334

2074.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1351_1373

876.3333333333334

2074.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1409_1417

876.3333333333334

2074.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1594_1763

876.3333333333334

2074.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

1961_2061

876.3333333333334

2074.0

Compositional bias

Note=Met-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1070_1104

693.3333333333334

1891.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1204_1207

693.3333333333334

1891.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1351_1373

693.3333333333334

1891.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1409_1417

693.3333333333334

1891.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1594_1763

693.3333333333334

1891.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

1961_2061

693.3333333333334

1891.0

Compositional bias

Note=Met-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1070_1104

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1204_1207

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1351_1373

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1409_1417

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1594_1763

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

1961_2061

584.3333333333334

1782.0

Compositional bias

Note=Met-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

599_605

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1070_1104

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1204_1207

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1351_1373

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1409_1417

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1594_1763

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

1961_2061

584.3333333333334

1782.0

Compositional bias

Note=Met-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

599_605

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1070_1104

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1204_1207

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1351_1373

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1409_1417

584.3333333333334

1782.0

Compositional bias

Note=Poly-Glu

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1594_1763

584.3333333333334

1782.0

Compositional bias

Note=Ser-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

1961_2061

584.3333333333334

1782.0

Compositional bias

Note=Met-rich

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

599_605

584.3333333333334

1782.0

Compositional bias

Note=Poly-Ser

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

715_989

876.3333333333334

2074.0

Domain

MYST-type HAT

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

715_989

693.3333333333334

1891.0

Domain

MYST-type HAT

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

715_989

584.3333333333334

1782.0

Domain

MYST-type HAT

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

715_989

584.3333333333334

1782.0

Domain

MYST-type HAT

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

715_989

584.3333333333334

1782.0

Domain

MYST-type HAT

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000287239

718_1008

876.3333333333334

2074.0

Region

Note=Catalytic

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

361_717

693.3333333333334

1891.0

Region

Note=Negatively regulates HAT activity

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

718_1008

693.3333333333334

1891.0

Region

Note=Catalytic

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

856_860

693.3333333333334

1891.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

865_871

693.3333333333334

1891.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

361_717

584.3333333333334

1782.0

Region

Note=Negatively regulates HAT activity

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

718_1008

584.3333333333334

1782.0

Region

Note=Catalytic

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

856_860

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

865_871

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

361_717

584.3333333333334

1782.0

Region

Note=Negatively regulates HAT activity

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

718_1008

584.3333333333334

1782.0

Region

Note=Catalytic

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

856_860

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

865_871

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

361_717

584.3333333333334

1782.0

Region

Note=Negatively regulates HAT activity

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

718_1008

584.3333333333334

1782.0

Region

Note=Catalytic

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

856_860

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

865_871

584.3333333333334

1782.0

Region

Acetyl-CoA binding

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372711

748_773

693.3333333333334

1891.0

Zinc finger

C2HC MYST-type

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372714

748_773

584.3333333333334

1782.0

Zinc finger

C2HC MYST-type

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372724

748_773

584.3333333333334

1782.0

Zinc finger

C2HC MYST-type

Hgene

KAT6B

chr10:76748870

chr10:75206331

ENST00000372725

748_773

584.3333333333334

1782.0

Zinc finger

C2HC MYST-type

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

11_21

395.3333333333333

525.0

Compositional bias

Poly-Pro

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

11_21

413.3333333333333

515.0

Compositional bias

Poly-Pro

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

11_21

395.3333333333333

516.0

Compositional bias

Poly-Pro

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

11_21

395.3333333333333

526.0

Compositional bias

Poly-Pro

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

316_320

395.3333333333333

525.0

Motif

SAPNY motif

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

316_320

413.3333333333333

515.0

Motif

SAPNY motif

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

316_320

395.3333333333333

516.0

Motif

SAPNY motif

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

316_320

395.3333333333333

526.0

Motif

SAPNY motif

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

357_379

395.3333333333333

525.0

Region

Calcineurin B binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000360663

65_356

395.3333333333333

525.0

Region

Catalytic

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

357_379

413.3333333333333

515.0

Region

Calcineurin B binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

401_415

413.3333333333333

515.0

Region

Calmodulin-binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394822

65_356

413.3333333333333

515.0

Region

Catalytic

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

357_379

395.3333333333333

516.0

Region

Calcineurin B binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394828

65_356

395.3333333333333

516.0

Region

Catalytic

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

357_379

395.3333333333333

526.0

Region

Calcineurin B binding

Tgene

PPP3CB

chr10:76748870

chr10:75206331

ENST00000394829

65_356

395.3333333333333

526.0

Region

Catalytic

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
KAT6B
PPP3CB

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000287239	+	13	18	752_1008	876.3333333333334	2074.0	BRPF1
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372711	+	12	17	752_1008	693.3333333333334	1891.0	BRPF1
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372714	+	12	17	752_1008	584.3333333333334	1782.0	BRPF1
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372724	+	13	18	752_1008	584.3333333333334	1782.0	BRPF1
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372725	+	12	17	752_1008	584.3333333333334	1782.0	BRPF1
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000287239	+	13	18	1560_2073	876.3333333333334	2074.0	RUNX1 and RUNX2
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372711	+	12	17	1560_2073	693.3333333333334	1891.0	RUNX1 and RUNX2
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372714	+	12	17	1560_2073	584.3333333333334	1782.0	RUNX1 and RUNX2
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372724	+	13	18	1560_2073	584.3333333333334	1782.0	RUNX1 and RUNX2
Hgene	KAT6B	chr10:76748870	chr10:75206331	ENST00000372725	+	12	17	1560_2073	584.3333333333334	1782.0	RUNX1 and RUNX2

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Related Drugs to KAT6B-PPP3CB

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to KAT6B-PPP3CB

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source