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Center for Computational Systems Medicine level3
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Potential Active Site Information

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Potentially Interacting Small Molecules through Virtual Screening

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Biochemical Features of Small Molecules with ADME

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Drug Toxicity Information

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:KLK2-FGFR2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: KLK2-FGFR2
FusionPDB ID: 43056
FusionGDB2.0 ID: 43056
HgeneTgene
Gene symbol

KLK2

FGFR2

Gene ID

3817

2263

Gene namekallikrein related peptidase 2fibroblast growth factor receptor 2
SynonymsKLK2A2|hGK-1|hK2BBDS|BEK|BFR-1|CD332|CEK3|CFD1|ECT1|JWS|K-SAM|KGFR|TK14|TK25
Cytomap

19q13.33

10q26.13

Type of geneprotein-codingprotein-coding
Descriptionkallikrein-2glandular kallikrein 2glandular kallikrein-1kallikrein 2, prostatictissue kallikrein-2fibroblast growth factor receptor 2BEK fibroblast growth factor receptorbacteria-expressed kinasekeratinocyte growth factor receptorprotein tyrosine kinase, receptor like 14
Modification date2020031320200322
UniProtAcc

P20151

P21802

Ensembl transtripts involved in fusion geneENST idsENST00000325321, ENST00000358049, 
ENST00000391810, ENST00000597509, 
ENST00000359354, ENST00000490349, 
ENST00000478859, ENST00000346997, 
ENST00000351936, ENST00000356226, 
ENST00000357555, ENST00000358487, 
ENST00000360144, ENST00000369056, 
ENST00000369059, ENST00000369060, 
ENST00000369061, ENST00000457416, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score21 X 19 X 4=159611 X 11 X 8=968
# samples 3016
** MAII scorelog2(30/1596*10)=-2.41142624572647
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/968*10)=-2.59693514238723
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: KLK2 [Title/Abstract] AND FGFR2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)KLK2(51376775)-FGFR2(123310973), # samples:9
Anticipated loss of major functional domain due to fusion event.KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a kinase by not retaining the major functional domain in the partially deleted in-frame ORF.
KLK2-FGFR2 seems lost the major protein functional domain in Hgene partner, which is a kinase by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneFGFR2

GO:0008284

positive regulation of cell proliferation

8663044

TgeneFGFR2

GO:0008543

fibroblast growth factor receptor signaling pathway

8663044|15629145

TgeneFGFR2

GO:0018108

peptidyl-tyrosine phosphorylation

15629145|16844695

TgeneFGFR2

GO:0046777

protein autophosphorylation

15629145


check buttonFusion gene breakpoints across KLK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FGFR2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-V1-A9O5-01AKLK2chr19

51376775

-FGFR2chr10

123310973

-
ChimerDB4PRADTCGA-V1-A9O5-06AKLK2chr19

51376774

+FGFR2chr10

123310972

-
ChimerDB4PRADTCGA-V1-A9O5-06AKLK2chr19

51376775

-FGFR2chr10

123310973

-
ChimerDB4PRADTCGA-V1-A9O5KLK2chr19

51376775

+FGFR2chr10

123310973

-
ChimerDB4PRADTCGA-V1-A9O5KLK2chr19

51380014

+FGFR2chr10

123310973

-
ChimerDB4UVMTCGA-V4-A9EA-01AKLK2chr19

51376775

-FGFR2chr10

123310973

-
ChimerDB4UVMTCGA-V4-A9EAKLK2chr19

51376775

+FGFR2chr10

123310973

-
ChimerKB4..KLK2chr19

51376774

FGFR2chr10

123310972



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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325321KLK2chr1951376774ENST00000369061FGFR2chr101233109723470271271946639
ENST00000325321KLK2chr1951376774ENST00000357555FGFR2chr101233109723455271272207726
ENST00000325321KLK2chr1951376774ENST00000358487FGFR2chr101233109723799271272282751
ENST00000325321KLK2chr1951376774ENST00000356226FGFR2chr101233109723062271272276749
ENST00000325321KLK2chr1951376774ENST00000369060FGFR2chr101233109722574271271934635
ENST00000325321KLK2chr1951376774ENST00000369059FGFR2chr101233109722524271272285752
ENST00000325321KLK2chr1951376774ENST00000346997FGFR2chr101233109722277271272276749
ENST00000325321KLK2chr1951376774ENST00000457416FGFR2chr101233109722286271272285752
ENST00000325321KLK2chr1951376774ENST00000351936FGFR2chr101233109722175271272174715
ENST00000325321KLK2chr1951376774ENST00000360144FGFR2chr101233109722464271272126699
ENST00000325321KLK2chr1951376774ENST00000369056FGFR2chr101233109722443271272126699
ENST00000358049KLK2chr1951376774ENST00000369061FGFR2chr10123310972326162161737573
ENST00000358049KLK2chr1951376774ENST00000357555FGFR2chr10123310972324662161998660
ENST00000358049KLK2chr1951376774ENST00000358487FGFR2chr10123310972359062162073685
ENST00000358049KLK2chr1951376774ENST00000356226FGFR2chr10123310972285362162067683
ENST00000358049KLK2chr1951376774ENST00000369060FGFR2chr10123310972236562161725569
ENST00000358049KLK2chr1951376774ENST00000369059FGFR2chr10123310972231562162076686
ENST00000358049KLK2chr1951376774ENST00000346997FGFR2chr10123310972206862162067684
ENST00000358049KLK2chr1951376774ENST00000457416FGFR2chr10123310972207762162076687
ENST00000358049KLK2chr1951376774ENST00000351936FGFR2chr10123310972196662161965650
ENST00000358049KLK2chr1951376774ENST00000360144FGFR2chr10123310972225562161917633
ENST00000358049KLK2chr1951376774ENST00000369056FGFR2chr10123310972223462161917633
ENST00000325321KLK2chr1951376775+ENST00000369061FGFR2chr10123310973-3470271271946639
ENST00000325321KLK2chr1951376775+ENST00000357555FGFR2chr10123310973-3455271272207726
ENST00000325321KLK2chr1951376775+ENST00000358487FGFR2chr10123310973-3799271272282751
ENST00000325321KLK2chr1951376775+ENST00000356226FGFR2chr10123310973-3062271272276749
ENST00000325321KLK2chr1951376775+ENST00000369060FGFR2chr10123310973-2574271271934635
ENST00000325321KLK2chr1951376775+ENST00000369059FGFR2chr10123310973-2524271272285752
ENST00000325321KLK2chr1951376775+ENST00000346997FGFR2chr10123310973-2277271272276749
ENST00000325321KLK2chr1951376775+ENST00000457416FGFR2chr10123310973-2286271272285752
ENST00000325321KLK2chr1951376775+ENST00000351936FGFR2chr10123310973-2175271272174715
ENST00000325321KLK2chr1951376775+ENST00000360144FGFR2chr10123310973-2464271272126699
ENST00000325321KLK2chr1951376775+ENST00000369056FGFR2chr10123310973-2443271272126699
ENST00000358049KLK2chr1951376775+ENST00000369061FGFR2chr10123310973-326162161737573
ENST00000358049KLK2chr1951376775+ENST00000357555FGFR2chr10123310973-324662161998660
ENST00000358049KLK2chr1951376775+ENST00000358487FGFR2chr10123310973-359062162073685
ENST00000358049KLK2chr1951376775+ENST00000356226FGFR2chr10123310973-285362162067683
ENST00000358049KLK2chr1951376775+ENST00000369060FGFR2chr10123310973-236562161725569
ENST00000358049KLK2chr1951376775+ENST00000369059FGFR2chr10123310973-231562162076686
ENST00000358049KLK2chr1951376775+ENST00000346997FGFR2chr10123310973-206862162067684
ENST00000358049KLK2chr1951376775+ENST00000457416FGFR2chr10123310973-207762162076687
ENST00000358049KLK2chr1951376775+ENST00000351936FGFR2chr10123310973-196662161965650
ENST00000358049KLK2chr1951376775+ENST00000360144FGFR2chr10123310973-225562161917633
ENST00000358049KLK2chr1951376775+ENST00000369056FGFR2chr10123310973-223462161917633
ENST00000325321KLK2chr1951380014+ENST00000369061FGFR2chr10123310973-39177187472393548
ENST00000325321KLK2chr1951380014+ENST00000357555FGFR2chr10123310973-39027187472654635
ENST00000325321KLK2chr1951380014+ENST00000358487FGFR2chr10123310973-42467187472729660
ENST00000325321KLK2chr1951380014+ENST00000356226FGFR2chr10123310973-35097187472723658
ENST00000325321KLK2chr1951380014+ENST00000369060FGFR2chr10123310973-30217187472381544
ENST00000325321KLK2chr1951380014+ENST00000369059FGFR2chr10123310973-29717187472732661
ENST00000325321KLK2chr1951380014+ENST00000346997FGFR2chr10123310973-27247187472723658
ENST00000325321KLK2chr1951380014+ENST00000457416FGFR2chr10123310973-27337187472732661
ENST00000325321KLK2chr1951380014+ENST00000351936FGFR2chr10123310973-26227187472621624
ENST00000325321KLK2chr1951380014+ENST00000360144FGFR2chr10123310973-29117187472573608
ENST00000325321KLK2chr1951380014+ENST00000369056FGFR2chr10123310973-28907187472573608
ENST00000391810KLK2chr1951380014+ENST00000369061FGFR2chr10123310973-35673683972043548
ENST00000391810KLK2chr1951380014+ENST00000357555FGFR2chr10123310973-35523683972304635
ENST00000391810KLK2chr1951380014+ENST00000358487FGFR2chr10123310973-38963683972379660
ENST00000391810KLK2chr1951380014+ENST00000356226FGFR2chr10123310973-31593683972373658
ENST00000391810KLK2chr1951380014+ENST00000369060FGFR2chr10123310973-26713683972031544
ENST00000391810KLK2chr1951380014+ENST00000369059FGFR2chr10123310973-26213683972382661
ENST00000391810KLK2chr1951380014+ENST00000346997FGFR2chr10123310973-23743683972373659
ENST00000391810KLK2chr1951380014+ENST00000457416FGFR2chr10123310973-23833683972382662
ENST00000391810KLK2chr1951380014+ENST00000351936FGFR2chr10123310973-22723683972271625
ENST00000391810KLK2chr1951380014+ENST00000360144FGFR2chr10123310973-25613683972223608
ENST00000391810KLK2chr1951380014+ENST00000369056FGFR2chr10123310973-25403683972223608
ENST00000358049KLK2chr1951380014+ENST00000369061FGFR2chr10123310973-37085095382184548
ENST00000358049KLK2chr1951380014+ENST00000357555FGFR2chr10123310973-36935095382445635
ENST00000358049KLK2chr1951380014+ENST00000358487FGFR2chr10123310973-40375095382520660
ENST00000358049KLK2chr1951380014+ENST00000356226FGFR2chr10123310973-33005095382514658
ENST00000358049KLK2chr1951380014+ENST00000369060FGFR2chr10123310973-28125095382172544
ENST00000358049KLK2chr1951380014+ENST00000369059FGFR2chr10123310973-27625095382523661
ENST00000358049KLK2chr1951380014+ENST00000346997FGFR2chr10123310973-25155095382514659
ENST00000358049KLK2chr1951380014+ENST00000457416FGFR2chr10123310973-25245095382523662
ENST00000358049KLK2chr1951380014+ENST00000351936FGFR2chr10123310973-24135095382412625
ENST00000358049KLK2chr1951380014+ENST00000360144FGFR2chr10123310973-27025095382364608
ENST00000358049KLK2chr1951380014+ENST00000369056FGFR2chr10123310973-26815095382364608
ENST00000325321KLK2chr1951376774+ENST00000369061FGFR2chr10123310972-3470271271946639
ENST00000325321KLK2chr1951376774+ENST00000357555FGFR2chr10123310972-3455271272207726
ENST00000325321KLK2chr1951376774+ENST00000358487FGFR2chr10123310972-3799271272282751
ENST00000325321KLK2chr1951376774+ENST00000356226FGFR2chr10123310972-3062271272276749
ENST00000325321KLK2chr1951376774+ENST00000369060FGFR2chr10123310972-2574271271934635
ENST00000325321KLK2chr1951376774+ENST00000369059FGFR2chr10123310972-2524271272285752
ENST00000325321KLK2chr1951376774+ENST00000346997FGFR2chr10123310972-2277271272276749
ENST00000325321KLK2chr1951376774+ENST00000457416FGFR2chr10123310972-2286271272285752
ENST00000325321KLK2chr1951376774+ENST00000351936FGFR2chr10123310972-2175271272174715
ENST00000325321KLK2chr1951376774+ENST00000360144FGFR2chr10123310972-2464271272126699
ENST00000325321KLK2chr1951376774+ENST00000369056FGFR2chr10123310972-2443271272126699
ENST00000358049KLK2chr1951376774+ENST00000369061FGFR2chr10123310972-326162161737573
ENST00000358049KLK2chr1951376774+ENST00000357555FGFR2chr10123310972-324662161998660
ENST00000358049KLK2chr1951376774+ENST00000358487FGFR2chr10123310972-359062162073685
ENST00000358049KLK2chr1951376774+ENST00000356226FGFR2chr10123310972-285362162067683
ENST00000358049KLK2chr1951376774+ENST00000369060FGFR2chr10123310972-236562161725569
ENST00000358049KLK2chr1951376774+ENST00000369059FGFR2chr10123310972-231562162076686
ENST00000358049KLK2chr1951376774+ENST00000346997FGFR2chr10123310972-206862162067684
ENST00000358049KLK2chr1951376774+ENST00000457416FGFR2chr10123310972-207762162076687
ENST00000358049KLK2chr1951376774+ENST00000351936FGFR2chr10123310972-196662161965650
ENST00000358049KLK2chr1951376774+ENST00000360144FGFR2chr10123310972-225562161917633
ENST00000358049KLK2chr1951376774+ENST00000369056FGFR2chr10123310972-223462161917633

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325321ENST00000369061KLK2chr1951376775+FGFR2chr10123310973-0.0004163720.99958366
ENST00000325321ENST00000357555KLK2chr1951376775+FGFR2chr10123310973-0.0003336720.99966633
ENST00000325321ENST00000358487KLK2chr1951376775+FGFR2chr10123310973-0.0003367920.99966323
ENST00000325321ENST00000356226KLK2chr1951376775+FGFR2chr10123310973-0.0007597710.9992403
ENST00000325321ENST00000369060KLK2chr1951376775+FGFR2chr10123310973-0.0005602250.9994398
ENST00000325321ENST00000369059KLK2chr1951376775+FGFR2chr10123310973-0.0014917660.99850816
ENST00000325321ENST00000346997KLK2chr1951376775+FGFR2chr10123310973-0.0020058860.9979942
ENST00000325321ENST00000457416KLK2chr1951376775+FGFR2chr10123310973-0.0018185740.99818146
ENST00000325321ENST00000351936KLK2chr1951376775+FGFR2chr10123310973-0.0020952430.9979048
ENST00000325321ENST00000360144KLK2chr1951376775+FGFR2chr10123310973-0.0017401120.99825984
ENST00000325321ENST00000369056KLK2chr1951376775+FGFR2chr10123310973-0.0020864930.99791354
ENST00000358049ENST00000369061KLK2chr1951376775+FGFR2chr10123310973-0.0003800130.99961996
ENST00000358049ENST00000357555KLK2chr1951376775+FGFR2chr10123310973-0.0003010720.999699
ENST00000358049ENST00000358487KLK2chr1951376775+FGFR2chr10123310973-0.000308150.99969184
ENST00000358049ENST00000356226KLK2chr1951376775+FGFR2chr10123310973-0.0006547280.99934524
ENST00000358049ENST00000369060KLK2chr1951376775+FGFR2chr10123310973-0.0004553120.9995447
ENST00000358049ENST00000369059KLK2chr1951376775+FGFR2chr10123310973-0.0012899970.99871004
ENST00000358049ENST00000346997KLK2chr1951376775+FGFR2chr10123310973-0.0016880060.998312
ENST00000358049ENST00000457416KLK2chr1951376775+FGFR2chr10123310973-0.001578760.9984212
ENST00000358049ENST00000351936KLK2chr1951376775+FGFR2chr10123310973-0.0017765420.9982235
ENST00000358049ENST00000360144KLK2chr1951376775+FGFR2chr10123310973-0.0015234590.99847656
ENST00000358049ENST00000369056KLK2chr1951376775+FGFR2chr10123310973-0.0018746980.99812526
ENST00000325321ENST00000369061KLK2chr1951380014+FGFR2chr10123310973-0.0004701860.99952984
ENST00000325321ENST00000357555KLK2chr1951380014+FGFR2chr10123310973-0.0008272560.99917275
ENST00000325321ENST00000358487KLK2chr1951380014+FGFR2chr10123310973-0.0008630620.999137
ENST00000325321ENST00000356226KLK2chr1951380014+FGFR2chr10123310973-0.0012919710.998708
ENST00000325321ENST00000369060KLK2chr1951380014+FGFR2chr10123310973-0.0014699280.99853003
ENST00000325321ENST00000369059KLK2chr1951380014+FGFR2chr10123310973-0.0023098280.9976902
ENST00000325321ENST00000346997KLK2chr1951380014+FGFR2chr10123310973-0.0030382740.99696165
ENST00000325321ENST00000457416KLK2chr1951380014+FGFR2chr10123310973-0.0027033340.99729663
ENST00000325321ENST00000351936KLK2chr1951380014+FGFR2chr10123310973-0.0033461350.9966538
ENST00000325321ENST00000360144KLK2chr1951380014+FGFR2chr10123310973-0.0027593130.99724066
ENST00000325321ENST00000369056KLK2chr1951380014+FGFR2chr10123310973-0.0031692810.99683076
ENST00000391810ENST00000369061KLK2chr1951380014+FGFR2chr10123310973-0.0004508140.9995492
ENST00000391810ENST00000357555KLK2chr1951380014+FGFR2chr10123310973-0.0007789940.99922097
ENST00000391810ENST00000358487KLK2chr1951380014+FGFR2chr10123310973-0.0008250510.9991749
ENST00000391810ENST00000356226KLK2chr1951380014+FGFR2chr10123310973-0.0012738340.9987262
ENST00000391810ENST00000369060KLK2chr1951380014+FGFR2chr10123310973-0.0014378590.99856216
ENST00000391810ENST00000369059KLK2chr1951380014+FGFR2chr10123310973-0.0023587250.9976413
ENST00000391810ENST00000346997KLK2chr1951380014+FGFR2chr10123310973-0.0031353720.9968646
ENST00000391810ENST00000457416KLK2chr1951380014+FGFR2chr10123310973-0.0027620560.9972379
ENST00000391810ENST00000351936KLK2chr1951380014+FGFR2chr10123310973-0.003468490.99653155
ENST00000391810ENST00000360144KLK2chr1951380014+FGFR2chr10123310973-0.0028205170.9971795
ENST00000391810ENST00000369056KLK2chr1951380014+FGFR2chr10123310973-0.0032948810.9967051
ENST00000358049ENST00000369061KLK2chr1951380014+FGFR2chr10123310973-0.0004272480.9995727
ENST00000358049ENST00000357555KLK2chr1951380014+FGFR2chr10123310973-0.0007564080.9992436
ENST00000358049ENST00000358487KLK2chr1951380014+FGFR2chr10123310973-0.0007981710.99920183
ENST00000358049ENST00000356226KLK2chr1951380014+FGFR2chr10123310973-0.0011510270.9988489
ENST00000358049ENST00000369060KLK2chr1951380014+FGFR2chr10123310973-0.0012737050.9987263
ENST00000358049ENST00000369059KLK2chr1951380014+FGFR2chr10123310973-0.0020626250.99793744
ENST00000358049ENST00000346997KLK2chr1951380014+FGFR2chr10123310973-0.002713550.99728644
ENST00000358049ENST00000457416KLK2chr1951380014+FGFR2chr10123310973-0.0024176710.9975823
ENST00000358049ENST00000351936KLK2chr1951380014+FGFR2chr10123310973-0.0029936040.99700636
ENST00000358049ENST00000360144KLK2chr1951380014+FGFR2chr10123310973-0.0024515690.9975484
ENST00000358049ENST00000369056KLK2chr1951380014+FGFR2chr10123310973-0.0028604280.9971396
ENST00000325321ENST00000369061KLK2chr1951376774+FGFR2chr10123310972-0.0004163720.99958366
ENST00000325321ENST00000357555KLK2chr1951376774+FGFR2chr10123310972-0.0003336720.99966633
ENST00000325321ENST00000358487KLK2chr1951376774+FGFR2chr10123310972-0.0003367920.99966323
ENST00000325321ENST00000356226KLK2chr1951376774+FGFR2chr10123310972-0.0007597710.9992403
ENST00000325321ENST00000369060KLK2chr1951376774+FGFR2chr10123310972-0.0005602250.9994398
ENST00000325321ENST00000369059KLK2chr1951376774+FGFR2chr10123310972-0.0014917660.99850816
ENST00000325321ENST00000346997KLK2chr1951376774+FGFR2chr10123310972-0.0020058860.9979942
ENST00000325321ENST00000457416KLK2chr1951376774+FGFR2chr10123310972-0.0018185740.99818146
ENST00000325321ENST00000351936KLK2chr1951376774+FGFR2chr10123310972-0.0020952430.9979048
ENST00000325321ENST00000360144KLK2chr1951376774+FGFR2chr10123310972-0.0017401120.99825984
ENST00000325321ENST00000369056KLK2chr1951376774+FGFR2chr10123310972-0.0020864930.99791354
ENST00000358049ENST00000369061KLK2chr1951376774+FGFR2chr10123310972-0.0003800130.99961996
ENST00000358049ENST00000357555KLK2chr1951376774+FGFR2chr10123310972-0.0003010720.999699
ENST00000358049ENST00000358487KLK2chr1951376774+FGFR2chr10123310972-0.000308150.99969184
ENST00000358049ENST00000356226KLK2chr1951376774+FGFR2chr10123310972-0.0006547280.99934524
ENST00000358049ENST00000369060KLK2chr1951376774+FGFR2chr10123310972-0.0004553120.9995447
ENST00000358049ENST00000369059KLK2chr1951376774+FGFR2chr10123310972-0.0012899970.99871004
ENST00000358049ENST00000346997KLK2chr1951376774+FGFR2chr10123310972-0.0016880060.998312
ENST00000358049ENST00000457416KLK2chr1951376774+FGFR2chr10123310972-0.001578760.9984212
ENST00000358049ENST00000351936KLK2chr1951376774+FGFR2chr10123310972-0.0017765420.9982235
ENST00000358049ENST00000360144KLK2chr1951376774+FGFR2chr10123310972-0.0015234590.99847656
ENST00000358049ENST00000369056KLK2chr1951376774+FGFR2chr10123310972-0.0018746980.99812526

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>43056_43056_1_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000346997_length(amino acids)=749AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

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>43056_43056_2_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000351936_length(amino acids)=715AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS

--------------------------------------------------------------

>43056_43056_3_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000356226_length(amino acids)=749AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

--------------------------------------------------------------

>43056_43056_4_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000357555_length(amino acids)=726AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPC

--------------------------------------------------------------

>43056_43056_5_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000358487_length(amino acids)=751AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_6_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000360144_length(amino acids)=699AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL

--------------------------------------------------------------

>43056_43056_7_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000369056_length(amino acids)=699AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL

--------------------------------------------------------------

>43056_43056_8_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000369059_length(amino acids)=752AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL
GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS

--------------------------------------------------------------

>43056_43056_9_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000369060_length(amino acids)=635AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTAD
TPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN
IINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTE
NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA
NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHIN

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>43056_43056_10_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000369061_length(amino acids)=639AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVA
PGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS
STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIG
KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM
DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQY

--------------------------------------------------------------

>43056_43056_11_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000325321_FGFR2_chr10_123310972_ENST00000457416_length(amino acids)=752AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL
GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS

--------------------------------------------------------------

>43056_43056_12_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000346997_length(amino acids)=684AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_13_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000351936_length(amino acids)=650AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_14_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000356226_length(amino acids)=683AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_15_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000357555_length(amino acids)=660AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVV
MAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALF
DRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN

--------------------------------------------------------------

>43056_43056_16_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000358487_length(amino acids)=685AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVV
MAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALF
DRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN

--------------------------------------------------------------

>43056_43056_17_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000360144_length(amino acids)=633AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_18_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000369056_length(amino acids)=633AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_19_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000369059_length(amino acids)=686AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_20_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000369060_length(amino acids)=569AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

--------------------------------------------------------------

>43056_43056_21_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000369061_length(amino acids)=573AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQV
TVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKM
LKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTY
QLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT
LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRS

--------------------------------------------------------------

>43056_43056_22_KLK2-FGFR2_KLK2_chr19_51376774_ENST00000358049_FGFR2_chr10_123310972_ENST00000457416_length(amino acids)=687AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_23_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000346997_length(amino acids)=749AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

--------------------------------------------------------------

>43056_43056_24_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000351936_length(amino acids)=715AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS

--------------------------------------------------------------

>43056_43056_25_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000356226_length(amino acids)=749AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

--------------------------------------------------------------

>43056_43056_26_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000357555_length(amino acids)=726AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPC

--------------------------------------------------------------

>43056_43056_27_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000358487_length(amino acids)=751AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEY
TCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_28_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000360144_length(amino acids)=699AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL

--------------------------------------------------------------

>43056_43056_29_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000369056_length(amino acids)=699AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL

--------------------------------------------------------------

>43056_43056_30_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000369059_length(amino acids)=752AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL
GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS

--------------------------------------------------------------

>43056_43056_31_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000369060_length(amino acids)=635AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTAD
TPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN
IINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTE
NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA
NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHIN

--------------------------------------------------------------

>43056_43056_32_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000369061_length(amino acids)=639AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVA
PGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS
STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIG
KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM
DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQY

--------------------------------------------------------------

>43056_43056_33_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000325321_FGFR2_chr10_123310973_ENST00000457416_length(amino acids)=752AA_BP=80
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLREAPQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTE
KMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVE
RSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYIC
KVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVT
VSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQ
LARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTL
GGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS

--------------------------------------------------------------

>43056_43056_34_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000346997_length(amino acids)=684AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_35_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000351936_length(amino acids)=650AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_36_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000356226_length(amino acids)=683AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDR
VYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEE

--------------------------------------------------------------

>43056_43056_37_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000357555_length(amino acids)=660AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVV
MAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALF
DRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN

--------------------------------------------------------------

>43056_43056_38_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000358487_length(amino acids)=685AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAG
VNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKK
PDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVV
MAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALF
DRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTN

--------------------------------------------------------------

>43056_43056_39_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000360144_length(amino acids)=633AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_40_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000369056_length(amino acids)=633AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_41_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000369059_length(amino acids)=686AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_42_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000369060_length(amino acids)=569AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLAR
GMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSS

--------------------------------------------------------------

>43056_43056_43_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000369061_length(amino acids)=573AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQV
TVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKM
LKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTY
QLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT
LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRS

--------------------------------------------------------------

>43056_43056_44_KLK2-FGFR2_KLK2_chr19_51376775_ENST00000358049_FGFR2_chr10_123310973_ENST00000457416_length(amino acids)=687AA_BP=14
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDK
GNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSG
INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTK
KPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQV
VMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEAL
FDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTT

--------------------------------------------------------------

>43056_43056_45_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000346997_length(amino acids)=658AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_46_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000351936_length(amino acids)=624AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP

--------------------------------------------------------------

>43056_43056_47_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000356226_length(amino acids)=658AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_48_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000357555_length(amino acids)=635AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPCV

--------------------------------------------------------------

>43056_43056_49_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000358487_length(amino acids)=660AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCS

--------------------------------------------------------------

>43056_43056_50_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000360144_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_51_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000369056_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_52_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000369059_length(amino acids)=661AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_53_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000369060_length(amino acids)=544AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTADT
PMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNI
INLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTEN
NVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPAN
CTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHING

--------------------------------------------------------------

>43056_43056_54_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000369061_length(amino acids)=548AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVAP
GREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSS
TADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVL
VTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMD
KPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYP

--------------------------------------------------------------

>43056_43056_55_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000325321_FGFR2_chr10_123310973_ENST00000457416_length(amino acids)=661AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_56_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000346997_length(amino acids)=659AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_57_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000351936_length(amino acids)=625AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP

--------------------------------------------------------------

>43056_43056_58_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000356226_length(amino acids)=658AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_59_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000357555_length(amino acids)=635AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPCV

--------------------------------------------------------------

>43056_43056_60_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000358487_length(amino acids)=660AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCS

--------------------------------------------------------------

>43056_43056_61_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000360144_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_62_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000369056_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_63_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000369059_length(amino acids)=661AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_64_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000369060_length(amino acids)=544AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTADT
PMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNI
INLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTEN
NVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPAN
CTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHING

--------------------------------------------------------------

>43056_43056_65_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000369061_length(amino acids)=548AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVAP
GREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSS
TADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVL
VTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMD
KPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYP

--------------------------------------------------------------

>43056_43056_66_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000358049_FGFR2_chr10_123310973_ENST00000457416_length(amino acids)=662AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_67_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000346997_length(amino acids)=659AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_68_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000351936_length(amino acids)=625AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP

--------------------------------------------------------------

>43056_43056_69_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000356226_length(amino acids)=658AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAE
SSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDA
TEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARG
MEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSP
YPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSG

--------------------------------------------------------------

>43056_43056_70_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000357555_length(amino acids)=635AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPSHLPCV

--------------------------------------------------------------

>43056_43056_71_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000358487_length(amino acids)=660AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVS
AESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLA
RGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCS

--------------------------------------------------------------

>43056_43056_72_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000360144_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_73_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000369056_length(amino acids)=608AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG

--------------------------------------------------------------

>43056_43056_74_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000369059_length(amino acids)=661AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

>43056_43056_75_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000369060_length(amino acids)=544AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTADT
PMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNI
INLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTEN
NVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPAN
CTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHING

--------------------------------------------------------------

>43056_43056_76_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000369061_length(amino acids)=548AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVAP
GREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSS
TADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVL
VTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMD
KPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYP

--------------------------------------------------------------

>43056_43056_77_KLK2-FGFR2_KLK2_chr19_51380014_ENST00000391810_FGFR2_chr10_123310973_ENST00000457416_length(amino acids)=662AA_BP=
MEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVER
SPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICK
VSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTV
SAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQL
ARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLG
GSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSC

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:51376775/chr10:123310973)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KLK2

P20151

FGFR2

P21802

FUNCTION: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.FUNCTION: Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes and immature osteoblasts, but promotes apoptosis in differentiated osteoblasts. Phosphorylates PLCG1, FRS2 and PAK4. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. FGFR2 signaling is down-regulated by ubiquitination, internalization and degradation. Mutations that lead to constitutive kinase activation or impair normal FGFR2 maturation, internalization and degradation lead to aberrant signaling. Over-expressed FGFR2 promotes activation of STAT1. {ECO:0000269|PubMed:12529371, ECO:0000269|PubMed:15190072, ECO:0000269|PubMed:15629145, ECO:0000269|PubMed:16384934, ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:17311277, ECO:0000269|PubMed:17623664, ECO:0000269|PubMed:18374639, ECO:0000269|PubMed:19103595, ECO:0000269|PubMed:19387476, ECO:0000269|PubMed:19410646, ECO:0000269|PubMed:21596750, ECO:0000269|PubMed:8663044}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217154_247151.33333333333334820.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217256_358151.33333333333334820.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217481_770151.33333333333334820.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318154_247151.33333333333334786.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318256_358151.33333333333334786.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318481_770151.33333333333334786.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116154_24736.333333333333336705.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116256_35836.333333333333336705.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116481_77036.333333333333336705.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217154_24762.333333333333336708.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217256_35862.333333333333336708.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217481_77062.333333333333336708.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318154_247151.33333333333334822.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318256_358151.33333333333334822.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318481_770151.33333333333334822.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437154_247151.33333333333334255.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437256_358151.33333333333334255.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437481_770151.33333333333334255.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217154_24762.333333333333336681.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217256_35862.333333333333336681.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217481_77062.333333333333336681.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217154_247151.33333333333334770.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217256_358151.33333333333334770.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217481_770151.33333333333334770.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316154_247151.33333333333334706.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316256_358151.33333333333334706.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316481_770151.33333333333334706.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215154_247151.33333333333334710.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215256_358151.33333333333334710.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215481_770151.33333333333334710.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318154_247151.33333333333334823.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318256_358151.33333333333334823.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318481_770151.33333333333334823.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217154_247151.33333333333334820.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217256_358151.33333333333334820.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217481_770151.33333333333334820.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318154_247151.33333333333334786.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318256_358151.33333333333334786.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318481_770151.33333333333334786.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116154_24736.333333333333336705.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116256_35836.333333333333336705.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116481_77036.333333333333336705.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217154_24762.333333333333336708.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217256_35862.333333333333336708.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217481_77062.333333333333336708.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318154_247151.33333333333334822.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318256_358151.33333333333334822.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318481_770151.33333333333334822.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437154_247151.33333333333334255.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437256_358151.33333333333334255.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437481_770151.33333333333334255.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217154_24762.333333333333336681.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217256_35862.333333333333336681.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217481_77062.333333333333336681.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217154_247151.33333333333334770.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217256_358151.33333333333334770.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217481_770151.33333333333334770.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316154_247151.33333333333334706.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316256_358151.33333333333334706.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316481_770151.33333333333334706.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215154_247151.33333333333334710.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215256_358151.33333333333334710.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215481_770151.33333333333334710.0DomainProtein kinase
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318154_247151.33333333333334823.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318256_358151.33333333333334823.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318481_770151.33333333333334823.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217154_247151.33333333333334820.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217256_358151.33333333333334820.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217481_770151.33333333333334820.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318154_247151.33333333333334786.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318256_358151.33333333333334786.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318481_770151.33333333333334786.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116154_24736.333333333333336705.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116256_35836.333333333333336705.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116481_77036.333333333333336705.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217154_24762.333333333333336708.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217256_35862.333333333333336708.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217481_77062.333333333333336708.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318154_247151.33333333333334822.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318256_358151.33333333333334822.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318481_770151.33333333333334822.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437154_247151.33333333333334255.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437256_358151.33333333333334255.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437481_770151.33333333333334255.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217154_24762.333333333333336681.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217256_35862.333333333333336681.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217481_77062.333333333333336681.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217154_247151.33333333333334770.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217256_358151.33333333333334770.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217481_770151.33333333333334770.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316154_247151.33333333333334706.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316256_358151.33333333333334706.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316481_770151.33333333333334706.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215154_247151.33333333333334710.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215256_358151.33333333333334710.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215481_770151.33333333333334710.0DomainProtein kinase
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318154_247151.33333333333334823.0DomainNote=Ig-like C2-type 2
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318256_358151.33333333333334823.0DomainNote=Ig-like C2-type 3
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318481_770151.33333333333334823.0DomainProtein kinase
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217487_495151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217565_567151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318487_495151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318565_567151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116487_49536.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116565_56736.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217487_49562.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217565_56762.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318487_495151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318565_567151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437487_495151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437565_567151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217487_49562.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217565_56762.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217487_495151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217565_567151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316487_495151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316565_567151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215487_495151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215565_567151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318487_495151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318565_567151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217487_495151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217565_567151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318487_495151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318565_567151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116487_49536.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116565_56736.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217487_49562.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217565_56762.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318487_495151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318565_567151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437487_495151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437565_567151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217487_49562.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217565_56762.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217487_495151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217565_567151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316487_495151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316565_567151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215487_495151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215565_567151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318487_495151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318565_567151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217487_495151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217565_567151.33333333333334820.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318487_495151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318565_567151.33333333333334786.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116487_49536.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116565_56736.333333333333336705.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217487_49562.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217565_56762.333333333333336708.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318487_495151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318565_567151.33333333333334822.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437487_495151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437565_567151.33333333333334255.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217487_49562.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217565_56762.333333333333336681.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217487_495151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217565_567151.33333333333334770.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316487_495151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316565_567151.33333333333334706.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215487_495151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215565_567151.33333333333334710.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318487_495151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318565_567151.33333333333334823.0Nucleotide bindingATP
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217161_178151.33333333333334820.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318161_178151.33333333333334786.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116131_15136.333333333333336705.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116161_17836.333333333333336705.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217131_15162.333333333333336708.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217161_17862.333333333333336708.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318161_178151.33333333333334822.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437161_178151.33333333333334255.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217131_15162.333333333333336681.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217161_17862.333333333333336681.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217161_178151.33333333333334770.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316161_178151.33333333333334706.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215161_178151.33333333333334710.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318161_178151.33333333333334823.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217161_178151.33333333333334820.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318161_178151.33333333333334786.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116161_17836.333333333333336705.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217161_17862.333333333333336708.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318161_178151.33333333333334822.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437161_178151.33333333333334255.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217161_17862.333333333333336681.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217161_178151.33333333333334770.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316161_178151.33333333333334706.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215161_178151.33333333333334710.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318161_178151.33333333333334823.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217161_178151.33333333333334820.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318161_178151.33333333333334786.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116161_17836.333333333333336705.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217161_17862.333333333333336708.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318161_178151.33333333333334822.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437161_178151.33333333333334255.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217161_17862.333333333333336681.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217161_178151.33333333333334770.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316161_178151.33333333333334706.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215161_178151.33333333333334710.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318161_178151.33333333333334823.0RegionNote=Heparin-binding
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217399_821151.33333333333334820.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318399_821151.33333333333334786.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116399_82136.333333333333336705.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217399_82162.333333333333336708.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318399_821151.33333333333334822.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437399_821151.33333333333334255.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217399_82162.333333333333336681.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217399_821151.33333333333334770.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316399_821151.33333333333334706.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215399_821151.33333333333334710.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318399_821151.33333333333334823.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217399_821151.33333333333334820.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318399_821151.33333333333334786.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116399_82136.333333333333336705.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217399_82162.333333333333336708.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318399_821151.33333333333334822.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437399_821151.33333333333334255.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217399_82162.333333333333336681.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217399_821151.33333333333334770.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316399_821151.33333333333334706.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215399_821151.33333333333334710.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318399_821151.33333333333334823.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217399_821151.33333333333334820.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318399_821151.33333333333334786.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116399_82136.333333333333336705.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217399_82162.333333333333336708.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318399_821151.33333333333334822.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437399_821151.33333333333334255.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217399_82162.333333333333336681.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217399_821151.33333333333334770.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316399_821151.33333333333334706.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215399_821151.33333333333334710.0Topological domainCytoplasmic
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318399_821151.33333333333334823.0Topological domainCytoplasmic
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217378_398151.33333333333334820.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318378_398151.33333333333334786.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000356226116378_39836.333333333333336705.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000357555217378_39862.333333333333336708.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318378_398151.33333333333334822.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437378_398151.33333333333334255.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000360144217378_39862.333333333333336681.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217378_398151.33333333333334770.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316378_398151.33333333333334706.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215378_398151.33333333333334710.0TransmembraneHelical
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318378_398151.33333333333334823.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000346997217378_398151.33333333333334820.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000351936318378_398151.33333333333334786.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000356226116378_39836.333333333333336705.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000357555217378_39862.333333333333336708.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000358487318378_398151.33333333333334822.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035935437378_398151.33333333333334255.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000360144217378_39862.333333333333336681.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369056217378_398151.33333333333334770.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369060316378_398151.33333333333334706.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000369061215378_398151.33333333333334710.0TransmembraneHelical
TgeneFGFR2chr19:51376775chr10:123310973ENST00000457416318378_398151.33333333333334823.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000346997217378_398151.33333333333334820.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000351936318378_398151.33333333333334786.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000356226116378_39836.333333333333336705.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000357555217378_39862.333333333333336708.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000358487318378_398151.33333333333334822.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035935437378_398151.33333333333334255.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000360144217378_39862.333333333333336681.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369056217378_398151.33333333333334770.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369060316378_398151.33333333333334706.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000369061215378_398151.33333333333334710.0TransmembraneHelical
TgeneFGFR2chr19:51380014chr10:123310973ENST00000457416318378_398151.33333333333334823.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLK2chr19:51376774chr10:123310972ENST000003253211525_25815.333333333333334262.0DomainPeptidase S1
HgeneKLK2chr19:51376774chr10:123310972ENST00000325321+1525_25815.333333333333334262.0DomainPeptidase S1
HgeneKLK2chr19:51376774chr10:123310972ENST000003580491525_25815.333333333333334224.0DomainPeptidase S1
HgeneKLK2chr19:51376774chr10:123310972ENST00000358049+1525_25815.333333333333334224.0DomainPeptidase S1
HgeneKLK2chr19:51376774chr10:123310972ENST000003918101425_2580160.0DomainPeptidase S1
HgeneKLK2chr19:51376774chr10:123310972ENST00000391810+1425_2580160.0DomainPeptidase S1
HgeneKLK2chr19:51376775chr10:123310973ENST00000325321+1525_25815.333333333333334262.0DomainPeptidase S1
HgeneKLK2chr19:51376775chr10:123310973ENST00000358049+1525_25815.333333333333334224.0DomainPeptidase S1
HgeneKLK2chr19:51376775chr10:123310973ENST00000391810+1425_2580160.0DomainPeptidase S1
HgeneKLK2chr19:51380014chr10:123310973ENST00000325321+3525_258164.33333333333334262.0DomainPeptidase S1
HgeneKLK2chr19:51380014chr10:123310973ENST00000358049+3525_258164.33333333333334224.0DomainPeptidase S1
HgeneKLK2chr19:51380014chr10:123310973ENST00000391810+2425_25862.333333333333336160.0DomainPeptidase S1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000034699721725_125151.33333333333334820.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035193631825_125151.33333333333334786.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035622611625_12536.333333333333336705.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035755521725_12562.333333333333336708.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035848731825_125151.33333333333334822.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST000003593543725_125151.33333333333334255.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036014421725_12562.333333333333336681.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036905621725_125151.33333333333334770.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036906031625_125151.33333333333334706.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036906121525_125151.33333333333334710.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST0000045741631825_125151.33333333333334823.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000034699721725_125151.33333333333334820.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035193631825_125151.33333333333334786.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035622611625_12536.333333333333336705.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035755521725_12562.333333333333336708.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035848731825_125151.33333333333334822.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST000003593543725_125151.33333333333334255.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036014421725_12562.333333333333336681.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036905621725_125151.33333333333334770.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036906031625_125151.33333333333334706.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036906121525_125151.33333333333334710.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376775chr10:123310973ENST0000045741631825_125151.33333333333334823.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000034699721725_125151.33333333333334820.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035193631825_125151.33333333333334786.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035622611625_12536.333333333333336705.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035755521725_12562.333333333333336708.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035848731825_125151.33333333333334822.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST000003593543725_125151.33333333333334255.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036014421725_12562.333333333333336681.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036905621725_125151.33333333333334770.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036906031625_125151.33333333333334706.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036906121525_125151.33333333333334710.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51380014chr10:123310973ENST0000045741631825_125151.33333333333334823.0DomainNote=Ig-like C2-type 1
TgeneFGFR2chr19:51376774chr10:123310972ENST00000346997217131_151151.33333333333334820.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000351936318131_151151.33333333333334786.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000358487318131_151151.33333333333334822.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035935437131_151151.33333333333334255.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369056217131_151151.33333333333334770.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369060316131_151151.33333333333334706.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000369061215131_151151.33333333333334710.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST00000457416318131_151151.33333333333334823.0RegionDisordered
TgeneFGFR2chr19:51376774chr10:123310972ENST0000034699721722_377151.33333333333334820.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035193631822_377151.33333333333334786.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035622611622_37736.333333333333336705.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035755521722_37762.333333333333336708.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000035848731822_377151.33333333333334822.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST000003593543722_377151.33333333333334255.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036014421722_37762.333333333333336681.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036905621722_377151.33333333333334770.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036906031622_377151.33333333333334706.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000036906121522_377151.33333333333334710.0Topological domainExtracellular
TgeneFGFR2chr19:51376774chr10:123310972ENST0000045741631822_377151.33333333333334823.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000034699721722_377151.33333333333334820.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035193631822_377151.33333333333334786.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035622611622_37736.333333333333336705.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035755521722_37762.333333333333336708.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000035848731822_377151.33333333333334822.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST000003593543722_377151.33333333333334255.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036014421722_37762.333333333333336681.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036905621722_377151.33333333333334770.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036906031622_377151.33333333333334706.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000036906121522_377151.33333333333334710.0Topological domainExtracellular
TgeneFGFR2chr19:51376775chr10:123310973ENST0000045741631822_377151.33333333333334823.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000034699721722_377151.33333333333334820.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035193631822_377151.33333333333334786.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035622611622_37736.333333333333336705.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035755521722_37762.333333333333336708.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000035848731822_377151.33333333333334822.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST000003593543722_377151.33333333333334255.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036014421722_37762.333333333333336681.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036905621722_377151.33333333333334770.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036906031622_377151.33333333333334706.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000036906121522_377151.33333333333334710.0Topological domainExtracellular
TgeneFGFR2chr19:51380014chr10:123310973ENST0000045741631822_377151.33333333333334823.0Topological domainExtracellular


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file (423) >>>423.pdbFusion protein BP residue: 14
CIF file (423) >>>423.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSSSMNSNTPLVRITTRLS
STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVG
IDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLG
ACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKD
LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDIN
NIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGS
PYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ
LVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDP
569
3D view using mol* of 423 (AA BP:14)
PDB file (434) >>>434.pdbFusion protein BP residue: 14
CIF file (434) >>>434.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILC
RMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRIT
TRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMA
EAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNII
NLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQM
TFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLA
RDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFT
LGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRP
TFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVF
573
3D view using mol* of 434 (AA BP:14)
PDB file (505) >>>505.pdbFusion protein BP residue: 14
CIF file (505) >>>505.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAG
EYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGV
FLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESS
SSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGK
PLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM
EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVT
ENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSD
VWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM
633
3D view using mol* of 505 (AA BP:14)
PDB file (507) >>>507.pdbFusion protein BP residue: 80
CIF file (507) >>>507.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKVSAESSS
SMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKP
LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEME
MMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTE
NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMM
RDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDT
635
3D view using mol* of 507 (AA BP:80)
PDB file (511) >>>511.pdbFusion protein BP residue: 80
CIF file (511) >>>511.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVAPGREKEITASPDYLEIAIYC
IGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSA
ESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLT
LGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLV
SEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPP
GMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV
LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTH
QSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNEL
YMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPS
639
3D view using mol* of 511 (AA BP:80)
PDB file (525)KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFED
AGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSM
NSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLG
EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM
KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN
VMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS
FGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRD
CWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEPYSPCYPDPRX
650
PDB file (538) >>>538.pdbFusion protein BP residue: 14
CIF file (538) >>>538.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFED
AGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSS
SMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKP
LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEME
MMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTE
NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMM
RDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKPPCNPS
660
3D view using mol* of 538 (AA BP:14)
PDB file (555) >>>555.pdbFusion protein BP residue: 14
CIF file (555) >>>555.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFED
AGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSM
NSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLG
EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM
KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN
VMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS
FGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRD
CWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRS
683
3D view using mol* of 555 (AA BP:14)
PDB file (557)KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFED
AGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVSAESSSSM
NSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLG
EGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMM
KMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSY
DINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENN
VMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWS
FGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRD
CWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRS
684
PDB file (558) >>>558.pdbFusion protein BP residue: 14
CIF file (558) >>>558.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFED
AGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF
LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSS
SMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKP
LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEME
MMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY
SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTE
NNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV
WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMM
RDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDT
685
3D view using mol* of 558 (AA BP:14)
PDB file (560) >>>560.pdbFusion protein BP residue: 14
CIF file (560) >>>560.cif		KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAG
EYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGV
FLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESS
SSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGK
PLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM
EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVT
ENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSD
VWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM
MRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPD
686
3D view using mol* of 560 (AA BP:14)
PDB file (561)KLK2chr1951376774FGFR2chr10123310972
MWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPM
PTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENE
YGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQP
HIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAG
EYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCIGV
FLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESS
SSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGK
PLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEM
EMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGME
YSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVT
ENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSD
VWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMM
MRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPD
687
PDB file (570) >>>570.pdbFusion protein BP residue: 80
CIF file (570) >>>570.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSS
NAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEI
TASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLT
KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELP
EDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASK
GNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLAS
QKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKW
MAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG
699
3D view using mol* of 570 (AA BP:80)
PDB file (587) >>>587.pdbFusion protein BP residue: 80
CIF file (587) >>>587.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTT
DKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEIT
ASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDP
KWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKC
IHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAP
EALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM
DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDL
715
3D view using mol* of 587 (AA BP:80)
PDB file (594) >>>594.pdbFusion protein BP residue: 80
CIF file (594) >>>594.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTT
DKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEIT
ASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPE
DPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
NLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQ
KCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWM
APEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH
RMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEEK
726
3D view using mol* of 594 (AA BP:80)
PDB file (613) >>>613.pdbFusion protein BP residue: 80
CIF file (613) >>>613.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTT
DKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEIT
ASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDP
KWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDD
ATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKC
IHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAP
EALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM
DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDL
749
3D view using mol* of 613 (AA BP:80)
PDB file (615) >>>615.pdbFusion protein BP residue: 80
CIF file (615) >>>615.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTT
DKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEIT
ASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPE
DPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLK
DDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKG
NLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQ
KCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWM
APEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH
RMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYL
DLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVK
751
3D view using mol* of 615 (AA BP:80)
PDB file (617) >>>617.pdbFusion protein BP residue: 80
CIF file (617) >>>617.cif		KLK2chr1951376774FGFR2chr10123310972
MALPPLPQLWVWEGVVQPPAAWGGPWSASRCQQGKGGVLENEGFIGLLRE
APQPQTHHLAVDTCVSMWDLVLSIALSVGCTGAPYWTNTEKMEKRLHAVP
AANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMES
VVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVV
GGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSS
NAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEI
TASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLT
KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELP
EDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKML
KDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASK
GNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLAS
QKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKW
MAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG
HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEY
LDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSV
752
3D view using mol* of 617 (AA BP:80)


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
KLK2_pLDDT.png
all structure
all structure
FGFR2_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
KLK2_FGFR2_423_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_423_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_423_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_434_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_434_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_434_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_505_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_505_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_505_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_507_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_507_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_507_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_511_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_511_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_511_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_538_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_538_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_538_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_555_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_555_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_558_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_558_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_558_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_560_pLDDT.png (AA BP:14)
all structure
KLK2_FGFR2_560_pLDDT_and_active_sites.png (AA BP:14)
all structure
KLK2_FGFR2_560_violinplot.png (AA BP:14)
all structure
KLK2_FGFR2_570_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_570_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_570_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_587_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_587_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_587_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_594_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_594_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_594_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_613_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_613_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_615_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_615_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_615_violinplot.png (AA BP:80)
all structure
KLK2_FGFR2_617_pLDDT.png (AA BP:80)
all structure
KLK2_FGFR2_617_pLDDT_and_active_sites.png (AA BP:80)
all structure
KLK2_FGFR2_617_violinplot.png (AA BP:80)
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots
KLK2_FGFR2_423.png
all structure
KLK2_FGFR2_434.png
all structure
KLK2_FGFR2_505.png
all structure
KLK2_FGFR2_507.png
all structure
KLK2_FGFR2_538.png
all structure
KLK2_FGFR2_555.png
all structure
KLK2_FGFR2_558.png
all structure
KLK2_FGFR2_560.png
all structure
KLK2_FGFR2_570.png
all structure
KLK2_FGFR2_587.png
all structure
KLK2_FGFR2_594.png
all structure
KLK2_FGFR2_613.png
all structure
KLK2_FGFR2_617.png
all structure

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Potential Active Site Information


check button The potential binding sites of these fusion proteins were identified using SiteMap, a module of the Schrodinger suite.
Fusion AA seq ID in FusionPDBSite scoreSizeD scoreVolumeExposureEnclosureContactPhobicPhilicBalanceDon/AccResidues
4230.93163721.042945.3410.6790.4390.3930.2390.50.4790.904Chain A: 12,13,14,16,19,20,21,22,23,24,25,26,27,28
,29,30,31,32,33,34,36,37,38,39,40,41,42,44,45,46,4
7,48,56,57,58,59,72,74,76,77,78,79,81,83,84,92,93,
94,104,105,106,107,108,109,113,114,115,116,117,118
,119,120,121,122,123,124,125,126,127,128,129,130,1
31,132,133,134,135,136,138,139,140,141,142,143,144
,145,147,148,149,150,151,152,153,154,155,156,157,1
58,159,160,161,162,163,164,165,171,172,173,174,175
,176,177,178,179,180,181,182,183,184,185,186,187,1
88,189,190,191,192,193,194,195,196,197,198,199,200
,201,202,203,204,205,206,207,208,209,210,211,212,2
13,214,215,216,217,218,219,221,222,223,231,235,236
,237,238,239,240,241,242,243,244,263,265,266,267,2
68,269,270,271,272,273,274,275,276,277,278,279,280
,281,282,283,284,285,286,287,288,289,290,292,296,3
03,304,305,306,307,308,309,312,313,314,315,316,317
,318,319,321,322,323,326,327,340,341,342,343,344,3
60,363,364,366,367,368,369,370,372,373,374,378,379
,381,391,392,393,394,395,396,397,398,399,400,401,4
02,403,404,405,406,407,408,409,410,411,412,413,414
,415,416,417,418,420,421,422,423,424,425,426,427,4
28,429,430,431,432,450,451,457,461,464,465,466,467
,468,469,470,471,472,478,479,481,482,483,485,486,4
88,489,490,491,492,493,494,495,496,497,498,499,500
,501,502,503,504,506,507
4341.0593261.065818.7410.4550.7871.0320.9881.0640.9280.679Chain A: 239,240,242,243,244,245,246,247,267,269,2
70,271,278,279,282,283,285,286,300,316,317,318,319
,320,322,323,376,377,378,382,383,385,395,396,397,3
98,399,400,401,405,406,407,408,409,410,411,412,413
,415,416,417,418,419,422,426,427,428,429,430,431,4
32
5051.036171.0481777.4260.5170.7390.950.6231.0290.6060.754Chain A: 36,57,62,65,66,67,68,69,70,83,84,86,88,89
,93,308,309,310,311,312,352,353,355,356,357,358,35
9,360,380,382,383,384,391,392,394,395,396,397,398,
399,401,402,403,405,406,413,429,431,432,435,436,43
8,485,487,490,491,495,496,498,508,509,510,511,512,
513,514,515,518,519,520,521,522,523,524,525,526,52
7,528,529,530,531,532,533,534,535,539,540,541,543,
544,545,567,568,570,571,573,574,575
5071.071541.1555.660.5440.770.941.1630.9251.2570.719Chain A: 301,302,304,305,306,307,308,309,329,331,3
32,333,340,341,344,345,347,348,352,362,378,379,380
,381,384,385,438,440,444,445,447,457,458,459,460,4
61,462,463,473
5111.0761280.963237.3560.3990.8121.1280.4711.4230.3310.711Chain A: 443,465,467,471,472,473,474,475,476,477,4
82,483,484,488,492,493,494,495,496,498
5381.0323911.051282.4770.5140.7420.9430.7261.0270.7070.921Chain A: 309,311,351,354,355,356,357,358,359,379,3
81,382,383,390,391,393,394,395,396,397,398,400,401
,402,404,405,412,428,429,430,431,434,435,484,485,4
86,489,490,494,495,497,507,508,509,510,511,513,514
,517,518,519,520,521,522,523,524,525,526,527,528,5
29,530,541,542,543,544
5571.0496531.0761689.9610.5260.7480.9460.7480.9610.7790.919Chain A: 77,78,79,81,82,106,108,109,110,111,114,11
8,119,120,121,138,141,142,144,145,146,147,148,149,
150,201,202,203,204,205,206,207,208,209,210,211,21
2,379,380,381,382,383,384,385,386,387,389,391,399,
401,404,405,419,423,432,434,445,447,448,449,450,45
1,452,453,454,456,457,461,492,493,494,495,496,498,
499,501,511,512,513,514,515,516,517,519,520,521,52
2,523,524,527,528,529,530,531,532,533,534,537,538,
539,542,545,548,549,550,551,555,556,559
5581.0527481.0012309.7620.4470.7760.9890.6161.2410.4960.628Chain A: 34,35,36,37,38,64,65,67,68,69,70,71,72,74
,81,83,84,86,87,113,114,115,116,117,118,119,121,12
3,145,146,147,215,347,348,349,350,351,352,353,354,
355,356,357,377,379,380,381,388,389,392,393,396,40
0,410,426,427,428,429,430,431,432,433,435,436,437,
439,442,448,449,450,487,488,492,493,495,505,506,50
7,508,509,511,517,518,519,520,521,522,523,524,525,
526,527,528,529,530,531,537,538,540,542,563,564,56
5,567,568,570,571,572,575,579
5601.0771881.126636.9510.5350.7410.9781.3690.7931.7260.811Chain A: 350,352,353,355,356,357,358,359,360,380,3
82,383,384,389,391,392,395,396,398,399,403,413,427
,429,430,431,432,435,436,495,496,498,508,509,510,5
11,512,514,523,524,525,526,527,528
5701.0067731.0162681.9170.5680.7080.9220.5181.070.4840.763Chain A: 100,101,102,103,130,131,133,134,135,136,1
37,138,149,150,151,152,153,180,181,182,183,184,211
,212,213,214,215,216,251,275,276,373,374,375,376,3
77,378,418,419,420,421,422,423,424,425,426,446,448
,449,450,457,458,460,461,462,463,464,465,467,468,4
69,471,472,479,495,496,497,498,499,500,501,502,505
,506,508,509,510,511,515,516,517,519,520,521,522,5
24,551,552,553,555,556,557,558,561,562,564,574,575
,576,577,578,579,580,581,584,585,586,587,588,589,5
90,591,592,593,594,595,596,597,598,599,600,601,605
,606,607,609,611,619,625,628,629,632,633,634,635,6
36,637,638,639,640,641,644,651,653,654,656,657,658

5871.0146921.0322557.0650.5820.7190.8890.4921.0410.4720.939Chain A: 101,102,123,126,127,128,132,133,134,135,1
50,151,152,153,154,155,180,210,211,212,213,214,215
,216,217,218,245,247,249,250,252,253,255,276,277,3
68,369,370,371,372,373,374,375,396,397,398,399,402
,415,416,418,419,420,421,422,423,443,445,446,447,4
54,455,457,458,459,460,461,462,463,464,465,466,467
,468,469,470,476,481,483,490,492,493,494,495,496,4
98,499,501,548,549,550,553,554,558,559,561,571,572
,573,574,575,577,578,581,582,583,584,585,586,587,5
88,589,590,591,592,593,594,595,596,597,598,602,603
,604,606,607,608,630,631,637,638,641,645
5941.0216951.0342835.2380.5810.730.9310.5761.0550.5460.914Chain A: 100,101,102,130,135,136,150,151,152,153,1
79,180,181,183,184,210,211,212,213,214,215,216,217
,218,247,249,250,251,255,275,276,277,278,371,373,3
74,375,376,377,417,418,420,421,422,423,424,425,445
,447,448,449,456,457,459,460,461,462,463,464,466,4
67,468,470,471,478,494,496,497,500,501,503,504,507
,508,510,512,516,517,518,519,522,524,550,551,552,5
54,555,556,560,561,563,573,574,575,576,577,579,580
,583,584,585,586,588,589,590,591,592,593,594,595,5
96,597,598,599,600,604,605,606,608,610,624,628,630
,631,632,633,635,636,637,639,640,643,644,647,648
6151.0079201.0252430.1550.5170.7090.9060.5111.0440.4890.815Chain A: 100,101,102,103,123,124,126,127,128,131,1
32,133,134,135,152,153,154,155,180,181,182,183,184
,185,213,214,215,276,277,278,373,374,375,376,377,4
17,418,420,421,422,423,424,425,445,447,448,449,456
,457,459,460,461,462,463,464,466,467,468,470,471,4
78,494,495,496,497,498,500,501,507,508,510,511,512
,514,515,516,517,518,519,522,523,524,525,550,551,5
52,553,555,556,560,561,563,573,574,575,576,577,578
,579,580,581,583,584,585,586,587,588,589,590,591,5
92,593,594,595,596,597,598,599,600,604,605,606,608
,609,610,624,628,630,631,632,634,635,636,637,638,6
39,640,643,650,652,653,654,655,656
6171.1031541.132537.4810.5020.8131.0251.3360.9071.4740.878Chain A: 418,419,421,422,423,424,425,426,446,448,4
49,450,457,458,461,462,465,469,479,495,496,497,498
,501,502,561,562,564,574,575,576,577,578,580,590,5
94

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Potentially Interacting Small Molecules through Virtual Screening


check button The FDA-approved small molecule library molecules were subjected to virtual screening using the Glide.
Fusion AA seq ID in FusionPDBZINC IDDrugBank IDDrug nameDocking scoreGlide gscore

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check button Drug information from DrugBank of the top 20 interacting small molecules.
ZINC IDDrugBank IDDrug nameDrug typeSMILESDrug group

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Biochemical Features of Small Molecules


check button ADME (Absorption, Distribution, Metabolism, and Excretion) of drugs using QikProp(v3.9)
ZINC IDmol_MWdipoleSASAFOSAFISAPISAWPSAvolumedonorHBaccptHBIPHuman Oral AbsorptionPercent Human Oral AbsorptionRule Of FiveRule Of Three


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Drug Toxicity Information


check button Toxicity information of individual drugs using eToxPred
ZINC IDSmileSurface AccessibilityToxicity


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors
KLK2SERPINF2, SERPINA3, SERPINA5, SERPINB6, APP, SUZ12, RNF2, ADAMTS1, SERPINE2, APLP2, GLG1, EXT2, BMP1, PIGT, FGFR4, MAN2B2, SUMF1, LRP6, JAG2, IL17RA, GALNT18, CERCAM, CHID1, PGAM2, ERGIC1, ROR2, PCSK9, B4GALT3, PCSK6, ARSK, MAN2A2, MANBA,


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
KLK2all structure
FGFR2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to KLK2-FGFR2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID
KLK2FGFR2Fgfr InhibitorsPubMed31043681

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Related Diseases to KLK2-FGFR2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID
KLK2FGFR2Metastatic Prostate CancerPubMed31043681
KLK2FGFR2CholangiocarcinomaMyCancerGenome
KLK2FGFR2Adenocarcinoma Of Unknown PrimaryMyCancerGenome
KLK2FGFR2Adenocarcinoma Of The Gastroesophageal JunctionMyCancerGenome
KLK2FGFR2Breast Invasive Ductal CarcinomaMyCancerGenome
KLK2FGFR2Esophageal AdenocarcinomaMyCancerGenome

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneKLK2C0033578Prostatic Neoplasms2CTD_human
HgeneKLK2C0376358Malignant neoplasm of prostate2CTD_human
TgeneFGFR2C2931196Craniofacial dysostosis type 123CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneFGFR2C0220658Pfeiffer Syndrome21CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneFGFR2C0001193Apert syndrome19CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C0795998JACKSON-WEISS SYNDROME10CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C0175699Saethre-Chotzen Syndrome8CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneFGFR2C1852406Cutis Gyrata Syndrome of Beare And Stevenson8CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C2936791Antley-Bixler Syndrome, Autosomal Dominant7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C1510455Acrocephalosyndactylia6CTD_human;ORPHANET
TgeneFGFR2C0265269Lacrimoauriculodentodigital syndrome5CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C0010278Craniosynostosis4CTD_human;GENOMICS_ENGLAND
TgeneFGFR2C1863389Apert-Crouzon Disease4CTD_human
TgeneFGFR2C1865070SCAPHOCEPHALY, MAXILLARY RETRUSION, AND MENTAL RETARDATION4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C0006142Malignant neoplasm of breast3CTD_human;UNIPROT
TgeneFGFR2C0030044Acrocephaly3CTD_human
TgeneFGFR2C0036341Schizophrenia3PSYGENET
TgeneFGFR2C0221356Brachycephaly3CTD_human
TgeneFGFR2C0265534Scaphycephaly3CTD_human
TgeneFGFR2C0265535Trigonocephaly3CTD_human
TgeneFGFR2C0376634Craniofacial Abnormalities3CTD_human
TgeneFGFR2C0678222Breast Carcinoma3CTD_human
TgeneFGFR2C1257931Mammary Neoplasms, Human3CTD_human
TgeneFGFR2C1458155Mammary Neoplasms3CTD_human
TgeneFGFR2C1833340Synostotic Posterior Plagiocephaly3CTD_human
TgeneFGFR2C1860819Metopic synostosis3CTD_human
TgeneFGFR2C2931150Synostotic Anterior Plagiocephaly3CTD_human
TgeneFGFR2C3281247BENT BONE DYSPLASIA SYNDROME3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneFGFR2C4551902Craniosynostosis, Type 13CTD_human
TgeneFGFR2C4704874Mammary Carcinoma, Human3CTD_human
TgeneFGFR2C0008925Cleft Palate2CTD_human
TgeneFGFR2C0011570Mental Depression2PSYGENET
TgeneFGFR2C0011581Depressive disorder2PSYGENET
TgeneFGFR2C0024623Malignant neoplasm of stomach2CGI;CTD_human
TgeneFGFR2C0038356Stomach Neoplasms2CGI;CTD_human
TgeneFGFR2C1708349Hereditary Diffuse Gastric Cancer2CTD_human
TgeneFGFR2C1837218Cleft palate, isolated2CTD_human
TgeneFGFR2C0000772Multiple congenital anomalies1CTD_human
TgeneFGFR2C0003090Ankylosis1CTD_human
TgeneFGFR2C0005586Bipolar Disorder1PSYGENET
TgeneFGFR2C0008924Cleft upper lip1CTD_human
TgeneFGFR2C0010273Craniofacial Dysostosis1CTD_human
TgeneFGFR2C0011757Developmental Coordination Disorder1CTD_human
TgeneFGFR2C0014170Endometrial Neoplasms1CTD_human
TgeneFGFR2C0018553Hamartoma Syndrome, Multiple1CTD_human
TgeneFGFR2C0020796Profound Mental Retardation1CTD_human
TgeneFGFR2C0023890Liver Cirrhosis1CTD_human
TgeneFGFR2C0024121Lung Neoplasms1CTD_human
TgeneFGFR2C0025363Mental Retardation, Psychosocial1CTD_human
TgeneFGFR2C0026613Motor Skills Disorders1CTD_human
TgeneFGFR2C0033975Psychotic Disorders1PSYGENET
TgeneFGFR2C0037268Skin Abnormalities1CTD_human
TgeneFGFR2C0037274Dermatologic disorders1CTD_human
TgeneFGFR2C0038219Status Dysraphicus1CTD_human
TgeneFGFR2C0040427Tooth Abnormalities1CTD_human
TgeneFGFR2C0080178Spina Bifida1CTD_human
TgeneFGFR2C0152423Congenital small ears1GENOMICS_ENGLAND
TgeneFGFR2C0206698Cholangiocarcinoma1CTD_human
TgeneFGFR2C0206762Limb Deformities, Congenital1CTD_human
TgeneFGFR2C0239946Fibrosis, Liver1CTD_human
TgeneFGFR2C0242379Malignant neoplasm of lung1CTD_human
TgeneFGFR2C0265326Bannayan-Riley-Ruvalcaba Syndrome1CTD_human
TgeneFGFR2C0266508Rachischisis1CTD_human
TgeneFGFR2C0345905Intrahepatic Cholangiocarcinoma1CTD_human
TgeneFGFR2C0349204Nonorganic psychosis1PSYGENET
TgeneFGFR2C0391826Lhermitte-Duclos disease1CTD_human
TgeneFGFR2C0476089Endometrial Carcinoma1CGI;CTD_human
TgeneFGFR2C0524730Odontome1CTD_human
TgeneFGFR2C0699791Stomach Carcinoma1CGI;GENOMICS_ENGLAND
TgeneFGFR2C0917816Mental deficiency1CTD_human
TgeneFGFR2C1450010Plagiocephaly, Nonsynostotic1CTD_human
TgeneFGFR2C1860042Antley-Bixler Syndrome with Disordered Steroidogenesis1CTD_human
TgeneFGFR2C1867564SCAPHOCEPHALY AND AXENFELD-RIEGER ANOMALY1GENOMICS_ENGLAND
TgeneFGFR2C1959582PTEN Hamartoma Tumor Syndrome1CTD_human
TgeneFGFR2C2350233Antley-Bixler Syndrome Phenotype1CTD_human
TgeneFGFR2C3267076Familial scaphocephaly syndrome1GENOMICS_ENGLAND
TgeneFGFR2C3714756Intellectual Disability1CTD_human
TgeneFGFR2C3805278Extrahepatic Cholangiocarcinoma1CTD_human