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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:LRIG3-SLC16A7

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: LRIG3-SLC16A7
FusionPDB ID: 49699
FusionGDB2.0 ID: 49699
HgeneTgene
Gene symbol

LRIG3

SLC16A7

Gene ID

121227

9194

Gene nameleucine rich repeats and immunoglobulin like domains 3solute carrier family 16 member 7
SynonymsLIG3MCT2
Cytomap

12q14.1

12q14.1

Type of geneprotein-codingprotein-coding
Descriptionleucine-rich repeats and immunoglobulin-like domains protein 3LIG-3monocarboxylate transporter 2solute carrier family 16 (monocarboxylate transporter), member 7solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Modification date2020031320200313
UniProtAcc

Q6UXM1

.
Ensembl transtripts involved in fusion geneENST idsENST00000320743, ENST00000379141, 
ENST00000543448, ENST00000261187, 
ENST00000549465, ENST00000549588, 
ENST00000552024, ENST00000547379, 
ENST00000552432, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score10 X 8 X 8=6409 X 8 X 7=504
# samples 1212
** MAII scorelog2(12/640*10)=-2.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/504*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: LRIG3 [Title/Abstract] AND SLC16A7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)LRIG3(59267837)-SLC16A7(60165000), # samples:2
Anticipated loss of major functional domain due to fusion event.LRIG3-SLC16A7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LRIG3-SLC16A7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC16A7

GO:1901475

pyruvate transmembrane transport

9786900


check buttonFusion gene breakpoints across LRIG3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC16A7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A1KU-01ALRIG3chr12

59267837

-SLC16A7chr12

60165000

+
ChimerDB4SARCTCGA-DX-A1KULRIG3chr12

59267836

-SLC16A7chr12

60164999

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379141LRIG3chr1259267837-ENST00000552432SLC16A7chr1260165000+47532999442181404
ENST00000379141LRIG3chr1259267837-ENST00000547379SLC16A7chr1260165000+45292999442181404
ENST00000320743LRIG3chr1259267837-ENST00000552432SLC16A7chr1260165000+5156340222146211466
ENST00000320743LRIG3chr1259267837-ENST00000547379SLC16A7chr1260165000+4932340222146211466
ENST00000379141LRIG3chr1259267836-ENST00000552432SLC16A7chr1260164999+47532999442181404
ENST00000379141LRIG3chr1259267836-ENST00000547379SLC16A7chr1260164999+45292999442181404
ENST00000320743LRIG3chr1259267836-ENST00000552432SLC16A7chr1260164999+5156340222146211466
ENST00000320743LRIG3chr1259267836-ENST00000547379SLC16A7chr1260164999+4932340222146211466

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379141ENST00000552432LRIG3chr1259267837-SLC16A7chr1260165000+0.0001401180.9998598
ENST00000379141ENST00000547379LRIG3chr1259267837-SLC16A7chr1260165000+0.0001859690.9998141
ENST00000320743ENST00000552432LRIG3chr1259267837-SLC16A7chr1260165000+0.0002174890.9997825
ENST00000320743ENST00000547379LRIG3chr1259267837-SLC16A7chr1260165000+0.0002970310.999703
ENST00000379141ENST00000552432LRIG3chr1259267836-SLC16A7chr1260164999+0.0001401180.9998598
ENST00000379141ENST00000547379LRIG3chr1259267836-SLC16A7chr1260164999+0.0001859690.9998141
ENST00000320743ENST00000552432LRIG3chr1259267836-SLC16A7chr1260164999+0.0002174890.9997825
ENST00000320743ENST00000547379LRIG3chr1259267836-SLC16A7chr1260164999+0.0002970310.999703

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>49699_49699_1_LRIG3-SLC16A7_LRIG3_chr12_59267836_ENST00000320743_SLC16A7_chr12_60164999_ENST00000547379_length(amino acids)=1466AA_BP=1060
MCRAPSARRLGASGRDLGRWTAMSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARL
PEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS
ELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQR
NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLN
TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGN
AFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSF
ICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKT
PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPS
FLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP
TCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGS
HHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKK
ECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGPVSSVLVNKYGSRPVVIAG
GLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILG
SLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYA
KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL
MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLS

--------------------------------------------------------------

>49699_49699_2_LRIG3-SLC16A7_LRIG3_chr12_59267836_ENST00000320743_SLC16A7_chr12_60164999_ENST00000552432_length(amino acids)=1466AA_BP=1060
MCRAPSARRLGASGRDLGRWTAMSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARL
PEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS
ELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQR
NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLN
TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGN
AFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSF
ICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKT
PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPS
FLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP
TCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGS
HHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKK
ECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGPVSSVLVNKYGSRPVVIAG
GLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILG
SLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYA
KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL
MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLS

--------------------------------------------------------------

>49699_49699_3_LRIG3-SLC16A7_LRIG3_chr12_59267836_ENST00000379141_SLC16A7_chr12_60164999_ENST00000547379_length(amino acids)=1404AA_BP=998
MKSGFSFGKPPQQNSVILQVMVDVLLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAG
NRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHL
ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC
QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRS
ITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG
FVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQ
CVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIED
IGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVS
DAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNL
PADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDP
FETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPAS
VASSNSFMGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKH
RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLA
QDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIG

--------------------------------------------------------------

>49699_49699_4_LRIG3-SLC16A7_LRIG3_chr12_59267836_ENST00000379141_SLC16A7_chr12_60164999_ENST00000552432_length(amino acids)=1404AA_BP=998
MKSGFSFGKPPQQNSVILQVMVDVLLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAG
NRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHL
ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC
QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRS
ITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG
FVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQ
CVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIED
IGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVS
DAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNL
PADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDP
FETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPAS
VASSNSFMGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKH
RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLA
QDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIG

--------------------------------------------------------------

>49699_49699_5_LRIG3-SLC16A7_LRIG3_chr12_59267837_ENST00000320743_SLC16A7_chr12_60165000_ENST00000547379_length(amino acids)=1466AA_BP=1060
MCRAPSARRLGASGRDLGRWTAMSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARL
PEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS
ELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQR
NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLN
TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGN
AFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSF
ICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKT
PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPS
FLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP
TCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGS
HHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKK
ECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGPVSSVLVNKYGSRPVVIAG
GLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILG
SLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYA
KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL
MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLS

--------------------------------------------------------------

>49699_49699_6_LRIG3-SLC16A7_LRIG3_chr12_59267837_ENST00000320743_SLC16A7_chr12_60165000_ENST00000552432_length(amino acids)=1466AA_BP=1060
MCRAPSARRLGASGRDLGRWTAMSAPSLRARAAGLGLLLCAVLGRAGRSDSGGRGELGQPSGVAAERPCPTTCRCLGDLLDCSRKRLARL
PEPLPSWVARLDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNIS
ELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHLELNRNKIKNVDGLTFQGLGALKSLKMQR
NGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFCQKLSELDLTFNHLSRLDDSSFLGLSLLN
TLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRSITKKAFTGLDALEHLDLSDNAIMSLQGN
AFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDGFVCDDFPKPQITVQPETQSAIKGSNLSF
ICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQCVISNHFGSSYSVKAKLTVNMLPSFTKT
PMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIEDIGVYSCTAQNSAGSISANATLTVLETPS
FLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVSDAGKYTCEMSNTLGTERGNVRLSVIPTP
TCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNLPADIPSYLSSQGTLADRQDGYVSSESGS
HHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDPFETYHTGCSPDPRTVLMDHYEPSYIKKK
ECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPASVASSNSFMGPVSSVLVNKYGSRPVVIAG
GLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILG
SLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYA
KDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETL
MDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLS

--------------------------------------------------------------

>49699_49699_7_LRIG3-SLC16A7_LRIG3_chr12_59267837_ENST00000379141_SLC16A7_chr12_60165000_ENST00000547379_length(amino acids)=1404AA_BP=998
MKSGFSFGKPPQQNSVILQVMVDVLLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAG
NRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHL
ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC
QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRS
ITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG
FVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQ
CVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIED
IGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVS
DAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNL
PADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDP
FETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPAS
VASSNSFMGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKH
RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLA
QDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIG

--------------------------------------------------------------

>49699_49699_8_LRIG3-SLC16A7_LRIG3_chr12_59267837_ENST00000379141_SLC16A7_chr12_60165000_ENST00000552432_length(amino acids)=1404AA_BP=998
MKSGFSFGKPPQQNSVILQVMVDVLLLFSLCLLFHISRPDLSHNRLSFIKASSMSHLQSLREVKLNNNELETIPNLGPVSANITLLSLAG
NRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPALQLKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAIPPKMFKLPQLQHL
ELNRNKIKNVDGLTFQGLGALKSLKMQRNGVTKLMDGAFWGLSNMEILQLDHNNLTEITKGWLYGLLMLQELHLSQNAINRISPDAWEFC
QKLSELDLTFNHLSRLDDSSFLGLSLLNTLHIGNNRVSYIADCAFRGLSSLKTLDLKNNEISWTIEDMNGAFSGLDKLRRLILQGNRIRS
ITKKAFTGLDALEHLDLSDNAIMSLQGNAFSQMKKLQQLHLNTSSLLCDCQLKWLPQWVAENNFQSFVNASCAHPQLLKGRSIFAVSPDG
FVCDDFPKPQITVQPETQSAIKGSNLSFICSAASSSDSPMTFAWKKDNELLHDAEMENYAHLRAQGGEVMEYTTILRLREVEFASEGKYQ
CVISNHFGSSYSVKAKLTVNMLPSFTKTPMDLTIRAGAMARLECAAVGHPAPQIAWQKDGGTDFPAARERRMHVMPEDDVFFIVDVKIED
IGVYSCTAQNSAGSISANATLTVLETPSFLRPLLDRTVTKGETAVLQCIAGGSPPPKLNWTKDDSPLVVTERHFFAAGNQLLIIVDSDVS
DAGKYTCEMSNTLGTERGNVRLSVIPTPTCDSPQMTAPSLDDDGWATVGVVIIAVVCCVVGTSLVWVVIIYHTRRRNEDCSITNTDETNL
PADIPSYLSSQGTLADRQDGYVSSESGSHHQFVTSSGAGFFLPQHDSSGTCHIDNSSEADVEAATDLFLCPFLGSTGPMYLKGNVYGSDP
FETYHTGCSPDPRTVLMDHYEPSYIKKKECYPCSHPSEESCERSFSNISWPSHVRKLLNTSYSHNEGPGMKNLCLNKSSLDFSANPEPAS
VASSNSFMGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGS
PVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKH
RGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLA
QDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIG

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:59267837/chr12:60165000)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LRIG3

Q6UXM1

.
FUNCTION: May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity). {ECO:0000250}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-181938_741038.33333333333331120.0DomainNote=LRRNT
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819444_4951038.33333333333331120.0DomainNote=LRRCT
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819499_5981038.33333333333331120.0DomainNote=Ig-like C2-type 1
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819603_6921038.33333333333331120.0DomainNote=Ig-like C2-type 2
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819697_7831038.33333333333331120.0DomainNote=Ig-like C2-type 3
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-181938_74978.33333333333341060.0DomainNote=LRRNT
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819444_495978.33333333333341060.0DomainNote=LRRCT
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819499_598978.33333333333341060.0DomainNote=Ig-like C2-type 1
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819603_692978.33333333333341060.0DomainNote=Ig-like C2-type 2
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819697_783978.33333333333341060.0DomainNote=Ig-like C2-type 3
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-181938_741038.33333333333331120.0DomainNote=LRRNT
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819444_4951038.33333333333331120.0DomainNote=LRRCT
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819499_5981038.33333333333331120.0DomainNote=Ig-like C2-type 1
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819603_6921038.33333333333331120.0DomainNote=Ig-like C2-type 2
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819697_7831038.33333333333331120.0DomainNote=Ig-like C2-type 3
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-181938_74978.33333333333341060.0DomainNote=LRRNT
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819444_495978.33333333333341060.0DomainNote=LRRCT
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819499_598978.33333333333341060.0DomainNote=Ig-like C2-type 1
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819603_692978.33333333333341060.0DomainNote=Ig-like C2-type 2
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819697_783978.33333333333341060.0DomainNote=Ig-like C2-type 3
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819122_1421038.33333333333331120.0RepeatNote=LRR 3
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819146_1671038.33333333333331120.0RepeatNote=LRR 4
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819168_1891038.33333333333331120.0RepeatNote=LRR 5
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819193_2141038.33333333333331120.0RepeatNote=LRR 6
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819216_2371038.33333333333331120.0RepeatNote=LRR 7
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819240_2611038.33333333333331120.0RepeatNote=LRR 8
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819264_2851038.33333333333331120.0RepeatNote=LRR 9
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819288_3091038.33333333333331120.0RepeatNote=LRR 10
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819312_3331038.33333333333331120.0RepeatNote=LRR 11
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819336_3571038.33333333333331120.0RepeatNote=LRR 12
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819360_3821038.33333333333331120.0RepeatNote=LRR 13
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819387_4081038.33333333333331120.0RepeatNote=LRR 14
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819411_4321038.33333333333331120.0RepeatNote=LRR 15
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-181975_961038.33333333333331120.0RepeatNote=LRR 1
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-181999_1201038.33333333333331120.0RepeatNote=LRR 2
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819122_142978.33333333333341060.0RepeatNote=LRR 3
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819146_167978.33333333333341060.0RepeatNote=LRR 4
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819168_189978.33333333333341060.0RepeatNote=LRR 5
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819193_214978.33333333333341060.0RepeatNote=LRR 6
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819216_237978.33333333333341060.0RepeatNote=LRR 7
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819240_261978.33333333333341060.0RepeatNote=LRR 8
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819264_285978.33333333333341060.0RepeatNote=LRR 9
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819288_309978.33333333333341060.0RepeatNote=LRR 10
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819312_333978.33333333333341060.0RepeatNote=LRR 11
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819336_357978.33333333333341060.0RepeatNote=LRR 12
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819360_382978.33333333333341060.0RepeatNote=LRR 13
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819387_408978.33333333333341060.0RepeatNote=LRR 14
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819411_432978.33333333333341060.0RepeatNote=LRR 15
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-181975_96978.33333333333341060.0RepeatNote=LRR 1
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-181999_120978.33333333333341060.0RepeatNote=LRR 2
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819122_1421038.33333333333331120.0RepeatNote=LRR 3
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819146_1671038.33333333333331120.0RepeatNote=LRR 4
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819168_1891038.33333333333331120.0RepeatNote=LRR 5
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819193_2141038.33333333333331120.0RepeatNote=LRR 6
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819216_2371038.33333333333331120.0RepeatNote=LRR 7
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819240_2611038.33333333333331120.0RepeatNote=LRR 8
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819264_2851038.33333333333331120.0RepeatNote=LRR 9
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819288_3091038.33333333333331120.0RepeatNote=LRR 10
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819312_3331038.33333333333331120.0RepeatNote=LRR 11
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819336_3571038.33333333333331120.0RepeatNote=LRR 12
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819360_3821038.33333333333331120.0RepeatNote=LRR 13
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819387_4081038.33333333333331120.0RepeatNote=LRR 14
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819411_4321038.33333333333331120.0RepeatNote=LRR 15
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-181975_961038.33333333333331120.0RepeatNote=LRR 1
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-181999_1201038.33333333333331120.0RepeatNote=LRR 2
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819122_142978.33333333333341060.0RepeatNote=LRR 3
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819146_167978.33333333333341060.0RepeatNote=LRR 4
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819168_189978.33333333333341060.0RepeatNote=LRR 5
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819193_214978.33333333333341060.0RepeatNote=LRR 6
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819216_237978.33333333333341060.0RepeatNote=LRR 7
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819240_261978.33333333333341060.0RepeatNote=LRR 8
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819264_285978.33333333333341060.0RepeatNote=LRR 9
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819288_309978.33333333333341060.0RepeatNote=LRR 10
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819312_333978.33333333333341060.0RepeatNote=LRR 11
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819336_357978.33333333333341060.0RepeatNote=LRR 12
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819360_382978.33333333333341060.0RepeatNote=LRR 13
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819387_408978.33333333333341060.0RepeatNote=LRR 14
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819411_432978.33333333333341060.0RepeatNote=LRR 15
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-181975_96978.33333333333341060.0RepeatNote=LRR 1
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-181999_120978.33333333333341060.0RepeatNote=LRR 2
HgeneLRIG3chr12:59267836chr12:60164999ENST00000320743-1819810_8301038.33333333333331120.0TransmembraneHelical
HgeneLRIG3chr12:59267836chr12:60164999ENST00000379141-1819810_830978.33333333333341060.0TransmembraneHelical
HgeneLRIG3chr12:59267837chr12:60165000ENST00000320743-1819810_8301038.33333333333331120.0TransmembraneHelical
HgeneLRIG3chr12:59267837chr12:60165000ENST00000379141-1819810_830978.33333333333341060.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000002611871581_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005473792681_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005520243781_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005524322681_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000002611871581_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005473792681_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005520243781_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226111_11572.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226137_14872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226170_17372.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226195_24672.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226268_28272.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226304_31272.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226334_33872.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226360_37372.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226395_40672.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226428_47872.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005524322681_8972.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000026118715407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000002611871590_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000054737926407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005473792690_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055202437407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005520243790_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST0000055243226407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005524322690_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000026118715407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000002611871590_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000054737926407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005473792690_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055202437407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005520243790_11072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226116_13672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226149_16972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226174_19472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226247_26772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226283_30372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226313_33372.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226339_35972.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226374_39472.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST0000055243226407_42772.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005524322690_11072.33333333333333479.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC16A7chr12:59267836chr12:60164999ENST00000261187151_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000002611871537_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST00000547379261_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005473792637_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST00000552024371_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005520243737_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST00000552432261_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005524322637_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST00000261187151_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000002611871537_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST00000547379261_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005473792637_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST00000552024371_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005520243737_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267837chr12:60165000ENST00000552432261_1572.33333333333333479.0Topological domainCytoplasmic
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005524322637_5972.33333333333333479.0Topological domainExtracellular
TgeneSLC16A7chr12:59267836chr12:60164999ENST000002611871516_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000002611871560_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005473792616_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005473792660_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005520243716_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005520243760_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005524322616_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267836chr12:60164999ENST000005524322660_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000002611871516_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000002611871560_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005473792616_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005473792660_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005520243716_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005520243760_8072.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005524322616_3672.33333333333333479.0TransmembraneHelical
TgeneSLC16A7chr12:59267837chr12:60165000ENST000005524322660_8072.33333333333333479.0TransmembraneHelical


Top

Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors
LRIG3CAND1, TAZ, TNFSF13B, PVRIG, GINM1, LPAR6, PTPRK, PTGER3, GAL3ST1, LRIG1, LRRN2, TMPRSS3, EGFR, ERBB2, ERBB4, KIAA1429, MTDH, PSMD14, ORF3a, E, M, nsp4, nsp6, nsp9, ORF6, ORF7a, ORF7b, TRIM66, LMO7, LIMCH1, ELOVL5, GJA1, HSD17B11, METTL7A, STX4, PDE3A, CLEC12B, SPSB4, OR10H1, CLGN, FBXO2, TMPRSS13, NRSN1, RLN1, RARRES1, LRRC4C, CLEC4A, SPSB2, ANPEP, DPP4, TMPRSS4,


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
LRIG3all structure
SLC16A7


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs to LRIG3-SLC16A7


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

Top

Related Diseases to LRIG3-SLC16A7


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource