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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ABLIM2-PPP2R2C

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ABLIM2-PPP2R2C
FusionPDB ID: 519
FusionGDB2.0 ID: 519
HgeneTgene
Gene symbol

ABLIM2

PPP2R2C

Gene ID

84448

5522

Gene nameactin binding LIM protein family member 2protein phosphatase 2 regulatory subunit Bgamma
Synonyms-B55-GAMMA|B55gamma|IMYPNO|IMYPNO1|PR52|PR55G
Cytomap

4p16.1

4p16.1

Type of geneprotein-codingprotein-coding
Descriptionactin-binding LIM protein 2abLIM-2testis tissue sperm-binding protein Li 35aprotein phosphatase 2, regulatory subunit B, gammaPP2A, subunit B, B-gamma isoformPP2A, subunit B, B55-gamma isoformPP2A, subunit B, PR55-gamma isoformPP2A, subunit B, R2-gamma isoformgamma isoform of regulatory subunit B55, protein phosphatase 2pho
Modification date2020031320200313
UniProtAcc

Q6H8Q1

.
Ensembl transtripts involved in fusion geneENST idsENST00000296372, ENST00000341937, 
ENST00000361581, ENST00000361737, 
ENST00000407564, ENST00000428004, 
ENST00000447017, ENST00000505872, 
ENST00000545242, ENST00000546334, 
ENST00000318888, ENST00000514025, 
ENST00000515079, 		ENST00000314348, 
ENST00000335585, ENST00000382599, 
ENST00000506140, ENST00000507294, 
ENST00000515571, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 4 X 3=486 X 6 X 5=180
# samples 46
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ABLIM2 [Title/Abstract] AND PPP2R2C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ABLIM2(8079355)-PPP2R2C(6380299), # samples:1
ABLIM2(8079355)-PPP2R2C(6382821), # samples:1
Anticipated loss of major functional domain due to fusion event.ABLIM2-PPP2R2C seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM2-PPP2R2C seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM2-PPP2R2C seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM2-PPP2R2C seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABLIM2-PPP2R2C seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ABLIM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPP2R2C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-FD-A3B4-01AABLIM2chr4

8079355

-PPP2R2Cchr4

6380299

-
ChimerDB4BLCATCGA-FD-A3B4-01AABLIM2chr4

8079355

-PPP2R2Cchr4

6382821

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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361737ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2331797591972637
ENST00000361737ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2229797591972637
ENST00000361737ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2219797591972637
ENST00000361737ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2114797591972637
ENST00000545242ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2352818141993659
ENST00000545242ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2250818141993659
ENST00000545242ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2240818141993659
ENST00000545242ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2135818141993659
ENST00000546334ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2352818141993659
ENST00000546334ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2250818141993659
ENST00000546334ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2240818141993659
ENST00000546334ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2135818141993659
ENST00000296372ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2352818141993659
ENST00000296372ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2250818141993659
ENST00000296372ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2240818141993659
ENST00000296372ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2135818141993659
ENST00000447017ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2229695201870616
ENST00000447017ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2127695201870616
ENST00000447017ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2117695201870616
ENST00000447017ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2012695201870616
ENST00000361581ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-227474021915637
ENST00000361581ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-217274021915637
ENST00000361581ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-216274021915637
ENST00000361581ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-205774021915637
ENST00000341937ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-227474021915637
ENST00000341937ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-217274021915637
ENST00000341937ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-216274021915637
ENST00000341937ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-205774021915637
ENST00000407564ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2303769311944637
ENST00000407564ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2201769311944637
ENST00000407564ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2191769311944637
ENST00000407564ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2086769311944637
ENST00000505872ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-220967501850616
ENST00000505872ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-210767501850616
ENST00000505872ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-209767501850616
ENST00000505872ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-199267501850616
ENST00000428004ABLIM2chr48079355-ENST00000506140PPP2R2Cchr46380299-2352818141993659
ENST00000428004ABLIM2chr48079355-ENST00000515571PPP2R2Cchr46380299-2250818141993659
ENST00000428004ABLIM2chr48079355-ENST00000382599PPP2R2Cchr46380299-2240818141993659
ENST00000428004ABLIM2chr48079355-ENST00000507294PPP2R2Cchr46380299-2135818141993659

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361737ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0047287080.99527127
ENST00000361737ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0060167680.9939832
ENST00000361737ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0060322980.99396765
ENST00000361737ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.0081541160.9918459
ENST00000545242ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0046516740.9953484
ENST00000545242ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059355770.9940644
ENST00000545242ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059506010.99404943
ENST00000545242ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.007937070.99206287
ENST00000546334ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0046516740.9953484
ENST00000546334ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059355770.9940644
ENST00000546334ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059506010.99404943
ENST00000546334ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.007937070.99206287
ENST00000296372ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0046516740.9953484
ENST00000296372ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059355770.9940644
ENST00000296372ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059506010.99404943
ENST00000296372ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.007937070.99206287
ENST00000447017ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0052424060.99475765
ENST00000447017ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0068720190.99312794
ENST00000447017ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0068619080.993138
ENST00000447017ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.0090516670.9909484
ENST00000361581ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0051542360.99484575
ENST00000361581ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.006675290.9933247
ENST00000361581ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0067585350.99324155
ENST00000361581ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.008954960.9910451
ENST00000341937ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0051542360.99484575
ENST00000341937ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.006675290.9933247
ENST00000341937ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0067585350.99324155
ENST00000341937ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.008954960.9910451
ENST00000407564ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0048382120.99516183
ENST00000407564ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0062503870.9937496
ENST00000407564ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0063063810.99369365
ENST00000407564ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.0083543050.99164575
ENST00000505872ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0049305750.9950694
ENST00000505872ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0064504770.9935495
ENST00000505872ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0065053860.9934947
ENST00000505872ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.0085263350.9914737
ENST00000428004ENST00000506140ABLIM2chr48079355-PPP2R2Cchr46380299-0.0046516740.9953484
ENST00000428004ENST00000515571ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059355770.9940644
ENST00000428004ENST00000382599ABLIM2chr48079355-PPP2R2Cchr46380299-0.0059506010.99404943
ENST00000428004ENST00000507294ABLIM2chr48079355-PPP2R2Cchr46380299-0.007937070.99206287

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>519_519_1_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000296372_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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>519_519_2_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000296372_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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>519_519_3_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000296372_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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>519_519_4_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000296372_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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>519_519_5_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000341937_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

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>519_519_6_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000341937_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

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>519_519_7_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000341937_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_8_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000341937_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_9_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361581_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_10_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361581_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_11_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361581_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_12_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361581_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=637AA_BP=0
LRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_13_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361737_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_14_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361737_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_15_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361737_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_16_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000361737_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_17_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000407564_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_18_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000407564_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_19_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000407564_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_20_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000407564_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=637AA_BP=1
MRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEY
ICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTE
IKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEF
DYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFAN
GHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDK
HSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSD
SVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQD

--------------------------------------------------------------

>519_519_21_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000428004_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_22_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000428004_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_23_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000428004_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_24_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000428004_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_25_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000447017_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_26_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000447017_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_27_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000447017_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_28_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000447017_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_29_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000505872_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_30_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000505872_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_31_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000505872_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_32_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000505872_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=616AA_BP=3
MSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFI
EGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKC
KSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQ
NAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSA
DDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEII
SSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKR

--------------------------------------------------------------

>519_519_33_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000545242_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_34_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000545242_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_35_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000545242_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_36_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000545242_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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>519_519_37_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000546334_PPP2R2C_chr4_6380299_ENST00000382599_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_38_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000546334_PPP2R2C_chr4_6380299_ENST00000506140_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_39_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000546334_PPP2R2C_chr4_6380299_ENST00000507294_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

--------------------------------------------------------------

>519_519_40_ABLIM2-PPP2R2C_ABLIM2_chr4_8079355_ENST00000546334_PPP2R2C_chr4_6380299_ENST00000515571_length(amino acids)=659AA_BP=1
MACAQGAGAEPAGGRRIARARHLRARGSGCRSAGPPRLRAAAEMSAVSQPQAAPSPLEKSPSTAILCNTCGNVCKGEVLRVQDKYFHIKC
FVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLP
VSVGSSAHLSQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLESK
NAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITERDKRPEGYNLKDEEGKLKDLSTVTSL
QVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLF
VYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSK
LCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFDRNTKRDVTLEASRESSKPRAVLKPRRVCVGGKRRRDDISVDSLDFTKKILHT

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:8079355/chr4:6380299)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABLIM2

Q6H8Q1

.
FUNCTION: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. {ECO:0000269|PubMed:17194709}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM2chr4:8079355chr4:6380299ENST00000341937-620151_210225.0612.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000341937-62022_81225.0612.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000341937-62081_141225.0612.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361581-618151_210225.0573.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361581-61822_81225.0573.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361581-61881_141225.0573.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361737-617151_210225.0532.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361737-61722_81225.0532.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361737-61781_141225.0532.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000407564-616151_210225.0522.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000407564-61622_81225.0522.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000407564-61681_141225.0522.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000428004-614151_210225.0471.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000428004-61422_81225.0471.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000428004-61481_141225.0471.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000447017-621151_210225.0646.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000447017-62122_81225.0646.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000447017-62181_141225.0646.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000505872-618151_210225.0560.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000505872-61822_81225.0560.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000505872-61881_141225.0560.0DomainLIM zinc-binding 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000033558519171_20956.0448.0RepeatNote=WD 3
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000033558519220_26056.0448.0RepeatNote=WD 4
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000033558519279_31756.0448.0RepeatNote=WD 5
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000033558519334_37556.0448.0RepeatNote=WD 6
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000033558519410_44656.0448.0RepeatNote=WD 7
TgenePPP2R2Cchr4:8079355chr4:6380299ENST000003355851987_12856.0448.0RepeatNote=WD 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000038259919171_20956.0448.0RepeatNote=WD 3
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000038259919220_26056.0448.0RepeatNote=WD 4
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000038259919279_31756.0448.0RepeatNote=WD 5
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000038259919334_37556.0448.0RepeatNote=WD 6
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000038259919410_44656.0448.0RepeatNote=WD 7
TgenePPP2R2Cchr4:8079355chr4:6380299ENST000003825991987_12856.0448.0RepeatNote=WD 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000506140210171_20949.0441.0RepeatNote=WD 3
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000506140210220_26049.0441.0RepeatNote=WD 4
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000506140210279_31749.0441.0RepeatNote=WD 5
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000506140210334_37549.0441.0RepeatNote=WD 6
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000506140210410_44649.0441.0RepeatNote=WD 7
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000050614021087_12849.0441.0RepeatNote=WD 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000507294210171_20949.0441.0RepeatNote=WD 3
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000507294210220_26049.0441.0RepeatNote=WD 4
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000507294210279_31749.0441.0RepeatNote=WD 5
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000507294210334_37549.0441.0RepeatNote=WD 6
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000507294210410_44649.0441.0RepeatNote=WD 7
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000050729421087_12849.0441.0RepeatNote=WD 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000515571210171_20939.0431.0RepeatNote=WD 3
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000515571210220_26039.0431.0RepeatNote=WD 4
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000515571210279_31739.0431.0RepeatNote=WD 5
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000515571210334_37539.0431.0RepeatNote=WD 6
TgenePPP2R2Cchr4:8079355chr4:6380299ENST00000515571210410_44639.0431.0RepeatNote=WD 7
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000051557121087_12839.0431.0RepeatNote=WD 2

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM2chr4:8079355chr4:6380299ENST00000318888-620151_2100347.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000318888-620210_2700347.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000318888-62022_810347.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000318888-620543_6110347.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000318888-62081_1410347.0DomainLIM zinc-binding 2
HgeneABLIM2chr4:8079355chr4:6380299ENST00000341937-620210_270225.0612.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000341937-620543_611225.0612.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361581-618210_270225.0573.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361581-618543_611225.0573.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361737-617210_270225.0532.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000361737-617543_611225.0532.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000407564-616210_270225.0522.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000407564-616543_611225.0522.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000428004-614210_270225.0471.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000428004-614543_611225.0471.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000447017-621210_270225.0646.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000447017-621543_611225.0646.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000505872-618210_270225.0560.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000505872-618543_611225.0560.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000514025-115151_2100347.0DomainLIM zinc-binding 3
HgeneABLIM2chr4:8079355chr4:6380299ENST00000514025-115210_2700347.0DomainLIM zinc-binding 4
HgeneABLIM2chr4:8079355chr4:6380299ENST00000514025-11522_810347.0DomainLIM zinc-binding 1
HgeneABLIM2chr4:8079355chr4:6380299ENST00000514025-115543_6110347.0DomainHP
HgeneABLIM2chr4:8079355chr4:6380299ENST00000514025-11581_1410347.0DomainLIM zinc-binding 2
TgenePPP2R2Cchr4:8079355chr4:6380299ENST000003355851922_6156.0448.0RepeatNote=WD 1
TgenePPP2R2Cchr4:8079355chr4:6380299ENST000003825991922_6156.0448.0RepeatNote=WD 1
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000050614021022_6149.0441.0RepeatNote=WD 1
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000050729421022_6149.0441.0RepeatNote=WD 1
TgenePPP2R2Cchr4:8079355chr4:6380299ENST0000051557121022_6139.0431.0RepeatNote=WD 1


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ABLIM2
PPP2R2C


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ABLIM2-PPP2R2C


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ABLIM2-PPP2R2C


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource