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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:OSBP2-NF2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: OSBP2-NF2
FusionPDB ID: 61753
FusionGDB2.0 ID: 61753
HgeneTgene
Gene symbol

OSBP2

NF2

Gene ID

23762

4771

Gene nameoxysterol binding protein 2neurofibromin 2
SynonymsHLM|ORP-4|ORP4|OSBPL1|OSBPL4ACN|BANF|SCH
Cytomap

22q12.2

22q12.2

Type of geneprotein-codingprotein-coding
Descriptionoxysterol-binding protein 2OSBP-related protein 4oxysterol binding protein-like 1oxysterol-binding protein-related protein 4merlinmoesin-ezrin-radixin likemoesin-ezrin-radixin-like proteinmoesin-ezrin-radizin-like proteinneurofibromin 2 (bilateral acoustic neuroma)schwannomerlinschwannomin
Modification date2020031320200322
UniProtAcc.

P35240

Ensembl transtripts involved in fusion geneENST idsENST00000332585, ENST00000382310, 
ENST00000401475, ENST00000403222, 
ENST00000407373, ENST00000437268, 
ENST00000446658, ENST00000496575, 
ENST00000535268, 		ENST00000334961, 
ENST00000338641, ENST00000347330, 
ENST00000353887, ENST00000361166, 
ENST00000361452, ENST00000361676, 
ENST00000397789, ENST00000403435, 
ENST00000403999, ENST00000413209, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score18 X 13 X 7=163815 X 13 X 7=1365
# samples 1817
** MAII scorelog2(18/1638*10)=-3.18586654531133
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1365*10)=-3.00529429966951
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: OSBP2 [Title/Abstract] AND NF2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)OSBP2(31266669)-NF2(30038191), # samples:1
Anticipated loss of major functional domain due to fusion event.OSBP2-NF2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
OSBP2-NF2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
OSBP2-NF2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
OSBP2-NF2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNF2

GO:0008285

negative regulation of cell proliferation

12444102|20178741

TgeneNF2

GO:0022408

negative regulation of cell-cell adhesion

17210637

TgeneNF2

GO:0042532

negative regulation of tyrosine phosphorylation of STAT protein

12444102

TgeneNF2

GO:0046426

negative regulation of JAK-STAT cascade

12444102


check buttonFusion gene breakpoints across OSBP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NF2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CX-7086-01AOSBP2chr22

31266669

+NF2chr22

30038191

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000403222OSBP2chr2231266669+ENST00000347330NF2chr2230038191+55848911441439431
ENST00000403222OSBP2chr2231266669+ENST00000413209NF2chr2230038191+48188911441025293
ENST00000403222OSBP2chr2231266669+ENST00000338641NF2chr2230038191+61128911442315723
ENST00000403222OSBP2chr2231266669+ENST00000403435NF2chr2230038191+26858911442213689
ENST00000403222OSBP2chr2231266669+ENST00000361452NF2chr2230038191+61538911442300718
ENST00000403222OSBP2chr2231266669+ENST00000403999NF2chr2230038191+31618911442300718
ENST00000403222OSBP2chr2231266669+ENST00000334961NF2chr2230038191+25258911442300718
ENST00000403222OSBP2chr2231266669+ENST00000353887NF2chr2230038191+23708911442300718
ENST00000403222OSBP2chr2231266669+ENST00000361166NF2chr2230038191+23658911442300718
ENST00000403222OSBP2chr2231266669+ENST00000397789NF2chr2230038191+23858911442300718
ENST00000403222OSBP2chr2231266669+ENST00000361676NF2chr2230038191+23708911442300718
ENST00000407373OSBP2chr2231266669+ENST00000347330NF2chr2230038191+54257321441280378
ENST00000407373OSBP2chr2231266669+ENST00000413209NF2chr2230038191+4659732144866240
ENST00000407373OSBP2chr2231266669+ENST00000338641NF2chr2230038191+59537321442156670
ENST00000407373OSBP2chr2231266669+ENST00000403435NF2chr2230038191+25267321442054636
ENST00000407373OSBP2chr2231266669+ENST00000361452NF2chr2230038191+59947321442141665
ENST00000407373OSBP2chr2231266669+ENST00000403999NF2chr2230038191+30027321442141665
ENST00000407373OSBP2chr2231266669+ENST00000334961NF2chr2230038191+23667321442141665
ENST00000407373OSBP2chr2231266669+ENST00000353887NF2chr2230038191+22117321442141665
ENST00000407373OSBP2chr2231266669+ENST00000361166NF2chr2230038191+22067321442141665
ENST00000407373OSBP2chr2231266669+ENST00000397789NF2chr2230038191+22267321442141665
ENST00000407373OSBP2chr2231266669+ENST00000361676NF2chr2230038191+22117321442141665
ENST00000332585OSBP2chr2231266669+ENST00000347330NF2chr2230038191+59041211531759568
ENST00000332585OSBP2chr2231266669+ENST00000413209NF2chr2230038191+51381211531345430
ENST00000332585OSBP2chr2231266669+ENST00000338641NF2chr2230038191+64321211532635860
ENST00000332585OSBP2chr2231266669+ENST00000403435NF2chr2230038191+30051211532533826
ENST00000332585OSBP2chr2231266669+ENST00000361452NF2chr2230038191+64731211532620855
ENST00000332585OSBP2chr2231266669+ENST00000403999NF2chr2230038191+34811211532620855
ENST00000332585OSBP2chr2231266669+ENST00000334961NF2chr2230038191+28451211532620855
ENST00000332585OSBP2chr2231266669+ENST00000353887NF2chr2230038191+26901211532620855
ENST00000332585OSBP2chr2231266669+ENST00000361166NF2chr2230038191+26851211532620855
ENST00000332585OSBP2chr2231266669+ENST00000397789NF2chr2230038191+27051211532620855
ENST00000332585OSBP2chr2231266669+ENST00000361676NF2chr2230038191+26901211532620855
ENST00000382310OSBP2chr2231266669+ENST00000347330NF2chr2230038191+58361143361691551
ENST00000382310OSBP2chr2231266669+ENST00000413209NF2chr2230038191+50701143361277413
ENST00000382310OSBP2chr2231266669+ENST00000338641NF2chr2230038191+63641143362567843
ENST00000382310OSBP2chr2231266669+ENST00000403435NF2chr2230038191+29371143362465809
ENST00000382310OSBP2chr2231266669+ENST00000361452NF2chr2230038191+64051143362552838
ENST00000382310OSBP2chr2231266669+ENST00000403999NF2chr2230038191+34131143362552838
ENST00000382310OSBP2chr2231266669+ENST00000334961NF2chr2230038191+27771143362552838
ENST00000382310OSBP2chr2231266669+ENST00000353887NF2chr2230038191+26221143362552838
ENST00000382310OSBP2chr2231266669+ENST00000361166NF2chr2230038191+26171143362552838
ENST00000382310OSBP2chr2231266669+ENST00000397789NF2chr2230038191+26371143362552838
ENST00000382310OSBP2chr2231266669+ENST00000361676NF2chr2230038191+26221143362552838
ENST00000446658OSBP2chr2231266669+ENST00000347330NF2chr2230038191+58211128211676551
ENST00000446658OSBP2chr2231266669+ENST00000413209NF2chr2230038191+50551128211262413
ENST00000446658OSBP2chr2231266669+ENST00000338641NF2chr2230038191+63491128212552843
ENST00000446658OSBP2chr2231266669+ENST00000403435NF2chr2230038191+29221128212450809
ENST00000446658OSBP2chr2231266669+ENST00000361452NF2chr2230038191+63901128212537838
ENST00000446658OSBP2chr2231266669+ENST00000403999NF2chr2230038191+33981128212537838
ENST00000446658OSBP2chr2231266669+ENST00000334961NF2chr2230038191+27621128212537838
ENST00000446658OSBP2chr2231266669+ENST00000353887NF2chr2230038191+26071128212537838
ENST00000446658OSBP2chr2231266669+ENST00000361166NF2chr2230038191+26021128212537838
ENST00000446658OSBP2chr2231266669+ENST00000397789NF2chr2230038191+26221128212537838
ENST00000446658OSBP2chr2231266669+ENST00000361676NF2chr2230038191+26071128212537838
ENST00000401475OSBP2chr2231266669+ENST00000347330NF2chr2230038191+5087394112942276
ENST00000401475OSBP2chr2231266669+ENST00000413209NF2chr2230038191+43213941434787215
ENST00000401475OSBP2chr2231266669+ENST00000338641NF2chr2230038191+56153941121818568
ENST00000401475OSBP2chr2231266669+ENST00000403435NF2chr2230038191+21883941121716534
ENST00000401475OSBP2chr2231266669+ENST00000361452NF2chr2230038191+56563941121803563
ENST00000401475OSBP2chr2231266669+ENST00000403999NF2chr2230038191+26643941121803563
ENST00000401475OSBP2chr2231266669+ENST00000334961NF2chr2230038191+20283941121803563
ENST00000401475OSBP2chr2231266669+ENST00000353887NF2chr2230038191+18733941121803563
ENST00000401475OSBP2chr2231266669+ENST00000361166NF2chr2230038191+18683941121803563
ENST00000401475OSBP2chr2231266669+ENST00000397789NF2chr2230038191+18883941121803563
ENST00000401475OSBP2chr2231266669+ENST00000361676NF2chr2230038191+18733941121803563
ENST00000437268OSBP2chr2231266669+ENST00000347330NF2chr2230038191+514144891996301
ENST00000437268OSBP2chr2231266669+ENST00000413209NF2chr2230038191+43754481488841215
ENST00000437268OSBP2chr2231266669+ENST00000338641NF2chr2230038191+5669448911872593
ENST00000437268OSBP2chr2231266669+ENST00000403435NF2chr2230038191+2242448911770559
ENST00000437268OSBP2chr2231266669+ENST00000361452NF2chr2230038191+5710448911857588
ENST00000437268OSBP2chr2231266669+ENST00000403999NF2chr2230038191+2718448911857588
ENST00000437268OSBP2chr2231266669+ENST00000334961NF2chr2230038191+2082448911857588
ENST00000437268OSBP2chr2231266669+ENST00000353887NF2chr2230038191+1927448911857588
ENST00000437268OSBP2chr2231266669+ENST00000361166NF2chr2230038191+1922448911857588
ENST00000437268OSBP2chr2231266669+ENST00000397789NF2chr2230038191+1942448911857588
ENST00000437268OSBP2chr2231266669+ENST00000361676NF2chr2230038191+1927448911857588

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000403222ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0144305490.9855694
ENST00000403222ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.0257289480.974271
ENST00000403222ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0062942310.9937058
ENST00000403222ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0094423710.9905577
ENST00000403222ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.0067831020.99321693
ENST00000403222ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0075150640.992485
ENST00000403222ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.013857340.9861427
ENST00000403222ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0158846860.98411536
ENST00000403222ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0159358340.9840642
ENST00000403222ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0159659070.98403406
ENST00000403222ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0158846860.98411536
ENST00000407373ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0167682170.9832318
ENST00000407373ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.017741490.98225844
ENST00000407373ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0118009520.988199
ENST00000407373ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0149350270.9850649
ENST00000407373ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.0123940190.98760605
ENST00000407373ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.012665630.9873344
ENST00000407373ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.0178379080.98216206
ENST00000407373ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0197476860.98025227
ENST00000407373ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0198201460.9801799
ENST00000407373ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0203106530.97968936
ENST00000407373ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0197476860.98025227
ENST00000332585ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0134404020.9865596
ENST00000332585ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.0210140370.978986
ENST00000332585ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0028561090.9971439
ENST00000332585ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0060906420.99390936
ENST00000332585ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.0030992760.9969008
ENST00000332585ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0044067710.99559325
ENST00000332585ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.009411590.9905884
ENST00000332585ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0105913640.9894086
ENST00000332585ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0106803170.9893197
ENST00000332585ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0102187790.98978126
ENST00000332585ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0105913640.9894086
ENST00000382310ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0135116050.9864884
ENST00000382310ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.0212277860.97877216
ENST00000382310ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0028749520.9971251
ENST00000382310ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0059267440.9940732
ENST00000382310ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.0031173180.9968827
ENST00000382310ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0043446930.9956553
ENST00000382310ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.0092056680.99079436
ENST00000382310ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0105712810.9894287
ENST00000382310ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0106535670.98934644
ENST00000382310ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0101943790.9898057
ENST00000382310ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0105712810.9894287
ENST00000446658ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0132372090.9867628
ENST00000446658ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.020687010.979313
ENST00000446658ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0028203750.9971796
ENST00000446658ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0057680240.994232
ENST00000446658ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.00305690.99694306
ENST00000446658ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0042141950.9957858
ENST00000446658ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.0090012370.99099874
ENST00000446658ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0103788480.98962116
ENST00000446658ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0104597480.9895403
ENST00000446658ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.010003890.9899961
ENST00000446658ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0103788480.98962116
ENST00000401475ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0082941240.9917059
ENST00000401475ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.770066140.22993387
ENST00000401475ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0036295920.99637043
ENST00000401475ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0042198880.9957801
ENST00000401475ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.0038526180.9961474
ENST00000401475ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0033045810.9966954
ENST00000401475ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.0042088240.9957912
ENST00000401475ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0049412410.9950588
ENST00000401475ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0049615680.99503845
ENST00000401475ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0050554560.9949445
ENST00000401475ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0049412410.9950588
ENST00000437268ENST00000347330OSBP2chr2231266669+NF2chr2230038191+0.0088052230.9911947
ENST00000437268ENST00000413209OSBP2chr2231266669+NF2chr2230038191+0.0167955180.9832045
ENST00000437268ENST00000338641OSBP2chr2231266669+NF2chr2230038191+0.0102425390.9897574
ENST00000437268ENST00000403435OSBP2chr2231266669+NF2chr2230038191+0.0128123520.9871876
ENST00000437268ENST00000361452OSBP2chr2231266669+NF2chr2230038191+0.010877760.9891222
ENST00000437268ENST00000403999OSBP2chr2231266669+NF2chr2230038191+0.0103029020.98969704
ENST00000437268ENST00000334961OSBP2chr2231266669+NF2chr2230038191+0.0136862450.9863137
ENST00000437268ENST00000353887OSBP2chr2231266669+NF2chr2230038191+0.0156079740.98439205
ENST00000437268ENST00000361166OSBP2chr2231266669+NF2chr2230038191+0.0155418390.98445815
ENST00000437268ENST00000397789OSBP2chr2231266669+NF2chr2230038191+0.0157365630.9842635
ENST00000437268ENST00000361676OSBP2chr2231266669+NF2chr2230038191+0.0156079740.98439205

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>61753_61753_1_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000334961_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_2_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000338641_length(amino acids)=860AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_3_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000347330_length(amino acids)=568AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEI
RNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGSTRGG

--------------------------------------------------------------

>61753_61753_4_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000353887_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_5_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000361166_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_6_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000361452_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_7_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000361676_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_8_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000397789_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_9_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000403435_length(amino acids)=826AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEE
AKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPM
NPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKH

--------------------------------------------------------------

>61753_61753_10_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000403999_length(amino acids)=855AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP
SESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWE
ERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKP
LDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKE
EATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLK
QDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTE

--------------------------------------------------------------

>61753_61753_11_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000332585_NF2_chr22_30038191_ENST00000413209_length(amino acids)=430AA_BP=386
MPPAPTGRSAARGSAGSMGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAV
SEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLG
VPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYH
LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIP

--------------------------------------------------------------

>61753_61753_12_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000334961_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_13_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000338641_length(amino acids)=843AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_14_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000347330_length(amino acids)=551AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDK
KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGSTRGGAKSQAEAPGDCHQAHVP

--------------------------------------------------------------

>61753_61753_15_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000353887_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_16_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000361166_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_17_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000361452_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_18_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000361676_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_19_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000397789_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_20_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000403435_length(amino acids)=809AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR
IKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLI

--------------------------------------------------------------

>61753_61753_21_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000403999_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_22_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000382310_NF2_chr22_30038191_ENST00000413209_length(amino acids)=413AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF

--------------------------------------------------------------

>61753_61753_23_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000334961_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_24_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000338641_length(amino acids)=568AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_25_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000347330_length(amino acids)=276AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVF
KFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGSTRGGAKSQAEAPGDCHQAHVPAHEPN

--------------------------------------------------------------

>61753_61753_26_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000353887_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_27_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000361166_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_28_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000361452_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_29_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000361676_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_30_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000397789_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_31_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000403435_length(amino acids)=534AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATA
IRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLS

--------------------------------------------------------------

>61753_61753_32_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000403999_length(amino acids)=563AA_BP=94
MLQNENPLTDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSN
AMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEY
LKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL
QLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEK
AQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIAT
KPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSD

--------------------------------------------------------------

>61753_61753_33_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000401475_NF2_chr22_30038191_ENST00000413209_length(amino acids)=215AA_BP=
MWSHRAYRSLVIAGLRVLTAVRPGSTPAPHRKERLWASGNGEDMSGSCLPLGPWSRVAGGGQRVPCTISSRTALPSPSAGSQPASQLLPK
VSPQPQLPCLFPTSCQPERRLGVPGGDPALARHELWAGSLTMRSRQACWPGIRRAGLLRCMPGPHRWGNECSGTLGGVGMMALASQGFSV

--------------------------------------------------------------

>61753_61753_34_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000334961_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_35_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000338641_length(amino acids)=723AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG
DSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKLTLQSAKSRVAFF

--------------------------------------------------------------

>61753_61753_36_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000347330_length(amino acids)=431AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFM

--------------------------------------------------------------

>61753_61753_37_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000353887_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_38_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000361166_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_39_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000361452_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_40_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000361676_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_41_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000397789_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_42_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000403435_length(amino acids)=689AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMA
EESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEK

--------------------------------------------------------------

>61753_61753_43_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000403999_length(amino acids)=718AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA
SYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTEL
LLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMK
AQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRI
KATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIG

--------------------------------------------------------------

>61753_61753_44_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000403222_NF2_chr22_30038191_ENST00000413209_length(amino acids)=293AA_BP=249
MHSSLGYRVRLSLKKEKKKKRKKKFADVLTILGSQPPLLWTYSGKMHRQRTRTMSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQE
RPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLA

--------------------------------------------------------------

>61753_61753_45_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000334961_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_46_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000338641_length(amino acids)=670AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_47_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000347330_length(amino acids)=378AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEF
TIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGSTRGGAKSQAEAPGD

--------------------------------------------------------------

>61753_61753_48_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000353887_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_49_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000361166_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_50_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000361452_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_51_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000361676_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_52_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000397789_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_53_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000403435_length(amino acids)=636AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAE
AEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPD
IPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGSSKHNTIKKPQAQG

--------------------------------------------------------------

>61753_61753_54_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000403999_length(amino acids)=665AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV
NERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEH
RGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKF
NSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALM
RSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAE
RRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERE

--------------------------------------------------------------

>61753_61753_55_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000407373_NF2_chr22_30038191_ENST00000413209_length(amino acids)=240AA_BP=196
MSSLAAKRLGMNRRPAGSGGGGGEAATWGHRFWRPQERPTDRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQ
QWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVV

--------------------------------------------------------------

>61753_61753_56_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000334961_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_57_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000338641_length(amino acids)=593AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_58_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000347330_length(amino acids)=301AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPW
NEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGST

--------------------------------------------------------------

>61753_61753_59_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000353887_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_60_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000361166_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_61_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000361452_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_62_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000361676_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_63_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000397789_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_64_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000403435_length(amino acids)=559AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQIT
EEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTY
PPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILHNENSDRGGS

--------------------------------------------------------------

>61753_61753_65_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000403999_length(amino acids)=588AA_BP=119
MEAAPPREMKGRGCWDTASVRSFCSSGCLNKFKKDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGL
KIPSESGEKLKVVNERATLFRITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPE
MWEERITAWYAEHRGRARDEAEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFT
IKPLDKKIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQ
MKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEAD
QLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNEL

--------------------------------------------------------------

>61753_61753_66_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000437268_NF2_chr22_30038191_ENST00000413209_length(amino acids)=215AA_BP=
MWSHRAYRSLVIAGLRVLTAVRPGSTPAPHRKERLWASGNGEDMSGSCLPLGPWSRVAGGGQRVPCTISSRTALPSPSAGSQPASQLLPK
VSPQPQLPCLFPTSCQPERRLGVPGGDPALARHELWAGSLTMRSRQACWPGIRRAGLLRCMPGPHRWGNECSGTLGGVGMMALASQGFSV

--------------------------------------------------------------

>61753_61753_67_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000334961_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_68_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000338641_length(amino acids)=843AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_69_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000347330_length(amino acids)=551AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDK
KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQGQRGRSAEAGPAGSTRGGAKSQAEAPGDCHQAHVP

--------------------------------------------------------------

>61753_61753_70_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000353887_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_71_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000361166_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_72_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000361452_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_73_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000361676_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_74_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000397789_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

--------------------------------------------------------------

>61753_61753_75_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000403435_length(amino acids)=809AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMKEEATMANEALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQEMQR
IKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKLLEIATKPTYPPMNPIPAPLPPDIPSFNLI

--------------------------------------------------------------

>61753_61753_76_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000403999_length(amino acids)=838AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
RITSNAMINVKKQILDEKIYCPPEASVLLASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWYAEHRGRARDE
AEMEYLKIAQDLEMYGVNYFAIRNKKGTELLLGVDALGLHIYDPENRLTPKISFPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRV
NKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREKQMREEAERTRDELERRLLQMKEEATMANEALMRSEETAD
LLAEKAQITEEEAKLLAQKAAEAEQEMQRIKATAIRTEEEKRLMEQKVLEAEVLALKMAEESERRAKEADQLKQDLQEAREAERRAKQKL
LEIATKPTYPPMNPIPAPLPPDIPSFNLIGDSLSFDFKDTDMKRLSMEIEKEKVEYMEKSKHLQEQLNELKTEIEALKLKERETALDILH

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>61753_61753_77_OSBP2-NF2_OSBP2_chr22_31266669_ENST00000446658_NF2_chr22_30038191_ENST00000413209_length(amino acids)=413AA_BP=369
MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEPERGPLSEQVSEAVSEAVPRSEPVSETTSEP
EPGAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSGARSYHLKASSEVDRQQWITALE
LAKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:31266669/chr22:30038191)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NF2

P35240

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex. {ECO:0000269|PubMed:20159598, ECO:0000269|PubMed:20178741, ECO:0000269|PubMed:21167305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOSBP2chr22:31266669chr22:30038191ENST00000332585+314182_274369.0917.0DomainPH
TgeneNF2chr22:31266669chr22:30038191ENST00000334961015327_46538.0451.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000338641216327_465121.0596.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000347330010327_46538.01312.6666666666667Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000353887015327_46538.0406.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000361166217327_465121.0571.3333333333334Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000361452116327_46580.01665.6666666666667Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000361676116327_46579.0531.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000397789217327_465121.0573.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000403435217327_465121.0541.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST00000403999216327_465121.0591.0Compositional biasNote=Glu-rich
TgeneNF2chr22:31266669chr22:30038191ENST0000041320925327_465121.0166.0Compositional biasNote=Glu-rich

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNF2chr22:31266669chr22:30038191ENST0000033496101522_31138.0451.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000033864121622_311121.0596.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000034733001022_31138.01312.6666666666667DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000035388701522_31138.0406.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000036116621722_311121.0571.3333333333334DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000036145211622_31180.01665.6666666666667DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000036167611622_31179.0531.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000039778921722_311121.0573.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000040343521722_311121.0541.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST0000040399921622_311121.0591.0DomainFERM
TgeneNF2chr22:31266669chr22:30038191ENST000004132092522_311121.0166.0DomainFERM


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
OSBP2
NF2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to OSBP2-NF2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to OSBP2-NF2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource