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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PARD3-NSUN6

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PARD3-NSUN6
FusionPDB ID: 62714
FusionGDB2.0 ID: 62714
HgeneTgene
Gene symbol

PARD3

NSUN6

Gene ID

56288

221078

Gene namepar-3 family cell polarity regulatorNOP2/Sun RNA methyltransferase 6
SynonymsASIP|Baz|PAR3|PAR3alpha|PARD-3|PARD3A|PPP1R118|SE2-5L16|SE2-5LT1|SE2-5T24933414E04Rik|ARL5B-AS1|NOPD1
Cytomap

10p11.22-p11.21

10p12.31

Type of geneprotein-codingprotein-coding
Descriptionpartitioning defective 3 homologCTCL tumor antigen se2-5PAR3-alphaatypical PKC isotype-specific interacting proteinbazookapar-3 family cell polarity regulator alphapar-3 partitioning defective 3 homologprotein phosphatase 1, regulatory subunit 118tRNA (cytosine(72)-C(5))-methyltransferase NSUN6ARL5B antisense RNA 1NOL1/NOP2/Sun and PUA domain-containing protein 1NOL1/NOP2/Sun domain family, member 6NOP2/Sun RNA methyltransferase family member 6NOP2/Sun domain family, member 6nucleolar protei
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000346874, ENST00000350537, 
ENST00000374788, ENST00000374789, 
ENST00000374790, ENST00000374794, 
ENST00000545260, ENST00000545693, 
ENST00000340077, ENST00000374768, 
ENST00000374773, ENST00000374776, 
ENST00000466092, ENST00000544292, 
ENST00000493816, ENST00000377304, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score33 X 20 X 14=92407 X 7 X 3=147
# samples 499
** MAII scorelog2(49/9240*10)=-4.23703919730085
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/147*10)=-0.70781924850669
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PARD3 [Title/Abstract] AND NSUN6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PARD3(34558585)-NSUN6(18905222), # samples:3
Anticipated loss of major functional domain due to fusion event.PARD3-NSUN6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PARD3-NSUN6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PARD3-NSUN6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PARD3-NSUN6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNSUN6

GO:0002946

tRNA C5-cytosine methylation

26160102

TgeneNSUN6

GO:0030488

tRNA methylation

28531330


check buttonFusion gene breakpoints across PARD3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NSUN6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7140-01APARD3chr10

34558585

-NSUN6chr10

18905222

-
ChimerDB4LUSCTCGA-77-7140PARD3chr10

34558584

-NSUN6chr10

18905222

-
ChimerDB4LUSCTCGA-77-7140PARD3chr10

34558585

-NSUN6chr10

18905222

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000545260PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-4959348819845861462
ENST00000545693PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5181371019848081536
ENST00000350537PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5087361619447141506
ENST00000346874PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5114364319447411515
ENST00000374789PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5225375419448521552
ENST00000374790PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5045357419446721492
ENST00000374794PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-4889341819445161440
ENST00000374788PARD3chr1034558585-ENST00000377304NSUN6chr1018905222-5216374519448431549
ENST00000545260PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-4959348819845861462
ENST00000545693PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5181371019848081536
ENST00000350537PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5087361619447141506
ENST00000346874PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5114364319447411515
ENST00000374789PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5225375419448521552
ENST00000374790PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5045357419446721492
ENST00000374794PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-4889341819445161440
ENST00000374788PARD3chr1034558584-ENST00000377304NSUN6chr1018905222-5216374519448431549

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545260ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0012032650.9987967
ENST00000545693ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0012371740.99876285
ENST00000350537ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0011561080.9988439
ENST00000346874ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0010829780.998917
ENST00000374789ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0012458850.99875414
ENST00000374790ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0013140160.998686
ENST00000374794ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0012072920.99879265
ENST00000374788ENST00000377304PARD3chr1034558585-NSUN6chr1018905222-0.0017154330.9982845
ENST00000545260ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0012032650.9987967
ENST00000545693ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0012371740.99876285
ENST00000350537ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0011561080.9988439
ENST00000346874ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0010829780.998917
ENST00000374789ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0012458850.99875414
ENST00000374790ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0013140160.998686
ENST00000374794ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0012072920.99879265
ENST00000374788ENST00000377304PARD3chr1034558584-NSUN6chr1018905222-0.0017154330.9982845

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>62714_62714_1_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000346874_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1515AA_BP=1149
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRL
PVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLG
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRIQAKTREFRER
QARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAV
LRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPR
YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVE
DTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCL

--------------------------------------------------------------

>62714_62714_2_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000350537_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1506AA_BP=1140
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSA
GLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNE
LKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSH
DDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTL
NGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKK
DKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAE
IQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAP
GIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPS
ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL
PESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQI

--------------------------------------------------------------

>62714_62714_3_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000374788_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1549AA_BP=1183
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVL
PPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIAD
ETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLE
EDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTG
KIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQ
VKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS
RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFN
KVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ
LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRL

--------------------------------------------------------------

>62714_62714_4_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000374789_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1552AA_BP=1186
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRL
PVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLG
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIE
KTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDAL
YAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGIS
ELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDK
IFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTA
AVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDM

--------------------------------------------------------------

>62714_62714_5_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000374790_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1492AA_BP=1126
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRII
RGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKE
KDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDEL
MYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDV
ISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEK
ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCS
GMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQ

--------------------------------------------------------------

>62714_62714_6_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000374794_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1440AA_BP=1074
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGSSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDK
SYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLG
DMFRIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKK
QQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMT
EPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA
FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAE
NEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST

--------------------------------------------------------------

>62714_62714_7_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000545260_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1462AA_BP=1096
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIE
KTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDAL
YAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGIS
ELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDK
IFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTA
AVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDM

--------------------------------------------------------------

>62714_62714_8_PARD3-NSUN6_PARD3_chr10_34558584_ENST00000545693_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1536AA_BP=1170
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSA
GLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNE
LKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSH
DDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAG
SPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRES
VSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEE
RIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVD
RKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKG
MGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG
LNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTC
TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKF

--------------------------------------------------------------

>62714_62714_9_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000346874_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1515AA_BP=1149
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRL
PVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLG
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRIQAKTREFRER
QARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAV
LRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPR
YLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVE
DTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCL

--------------------------------------------------------------

>62714_62714_10_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000350537_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1506AA_BP=1140
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSA
GLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNE
LKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSH
DDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTL
NGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKK
DKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAE
IQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAP
GIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPS
ALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFL
PESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQI

--------------------------------------------------------------

>62714_62714_11_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000374788_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1549AA_BP=1183
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVL
PPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIAD
ETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLE
EDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTG
KIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQ
VKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELS
RKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFN
KVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQ
LLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRL

--------------------------------------------------------------

>62714_62714_12_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000374789_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1552AA_BP=1186
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRL
PVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLG
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIE
KTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDAL
YAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGIS
ELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDK
IFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTA
AVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDM

--------------------------------------------------------------

>62714_62714_13_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000374790_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1492AA_BP=1126
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRII
RGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKE
KDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDEL
MYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDV
ISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEK
ILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCS
GMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQ

--------------------------------------------------------------

>62714_62714_14_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000374794_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1440AA_BP=1074
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGSSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDK
SYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLG
DMFRIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDRKNIKK
QQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKGMGIRMT
EPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLGLNSIRA
FCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTCTITLAE
NEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKFVKCKST

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>62714_62714_15_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000545260_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1462AA_BP=1096
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDD
MVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPA
ANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSG
YNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTV
SLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLI
AVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNA
ALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIE
KTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDAL
YAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGIS
ELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDK
IFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTA
AVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDM

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>62714_62714_16_PARD3-NSUN6_PARD3_chr10_34558585_ENST00000545693_NSUN6_chr10_18905222_ENST00000377304_length(amino acids)=1536AA_BP=1170
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSA
GLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNE
LKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSH
DDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAG
SPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRES
VSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEE
RIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVD
RKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGISELSRKEIFSGLPELKG
MGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDKIFNKVEKIKQNALLLG
LNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTAAVQLLKPEGVLVYSTC
TITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDMLRLANKDSIGFFIAKF

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Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:34558585/chr10:18905222)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-21241049_10771105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-21241049_10771096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-22251049_10771139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-22251049_10771142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-21241049_10771126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-21241049_10771105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-21241049_10771096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-22251049_10771139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-22251049_10771142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-21241049_10771126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-2124984_10421105.66666666666671320.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-2124984_10421096.66666666666671311.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-2225984_10421139.66666666666671354.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-2225984_10421142.66666666666671357.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-2023984_10421052.66666666666671267.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-2124984_10421126.66666666666671341.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-2124984_10421105.66666666666671320.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-2124984_10421096.66666666666671311.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-2225984_10421139.66666666666671354.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-2225984_10421142.66666666666671357.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-2023984_10421052.66666666666671267.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-2124984_10421126.66666666666671341.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-2124271_3591105.66666666666671320.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-2124461_5461105.66666666666671320.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-2124590_6771105.66666666666671320.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-2124271_3591096.66666666666671311.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-2124461_5461096.66666666666671311.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-2124590_6771096.66666666666671311.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-2225271_3591139.66666666666671354.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-2225461_5461139.66666666666671354.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-2225590_6771139.66666666666671354.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-2225271_3591142.66666666666671357.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-2225461_5461142.66666666666671357.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-2225590_6771142.66666666666671357.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-1821271_3591030.66666666666671245.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-1821461_5461030.66666666666671245.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-1821590_6771030.66666666666671245.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-2023271_3591052.66666666666671267.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-2023461_5461052.66666666666671267.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-2023590_6771052.66666666666671267.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-2124271_3591126.66666666666671341.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-2124461_5461126.66666666666671341.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-2124590_6771126.66666666666671341.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-2124271_3591105.66666666666671320.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-2124461_5461105.66666666666671320.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-2124590_6771105.66666666666671320.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-2124271_3591096.66666666666671311.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-2124461_5461096.66666666666671311.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-2124590_6771096.66666666666671311.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-2225271_3591139.66666666666671354.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-2225461_5461139.66666666666671354.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-2225590_6771139.66666666666671354.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-2225271_3591142.66666666666671357.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-2225461_5461142.66666666666671357.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-2225590_6771142.66666666666671357.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-1821271_3591030.66666666666671245.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-1821461_5461030.66666666666671245.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-1821590_6771030.66666666666671245.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-2023271_3591052.66666666666671267.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-2023461_5461052.66666666666671267.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-2023590_6771052.66666666666671267.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-2124271_3591126.66666666666671341.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-2124461_5461126.66666666666671341.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-2124590_6771126.66666666666671341.0DomainPDZ 3
TgeneNSUN6chr10:34558584chr10:18905222ENST00000377304211111_203103.66666666666667470.0DomainPUA
TgeneNSUN6chr10:34558585chr10:18905222ENST00000377304211111_203103.66666666666667470.0DomainPUA
TgeneNSUN6chr10:34558584chr10:18905222ENST00000377304211242_248103.66666666666667470.0RegionS-adenosyl-L-methionine binding
TgeneNSUN6chr10:34558585chr10:18905222ENST00000377304211242_248103.66666666666667470.0RegionS-adenosyl-L-methionine binding

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-1211049_107701032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-1211151_117401032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-1211201_122401032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-1211280_130101032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-21241151_11741105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-21241201_12241105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-21241280_13011105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-21241151_11741096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-21241201_12241096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-21241280_13011096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-1201049_10770989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-1201151_11740989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-1201201_12240989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-1201280_13010989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-22251151_11741139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-22251201_12241139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-22251280_13011139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-22251151_11741142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-22251201_12241142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-22251280_13011142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-18211049_10771030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-18211151_11741030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-18211201_12241030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-18211280_13011030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-20231049_10771052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-20231151_11741052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-20231201_12241052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-20231280_13011052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-21241151_11741126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-21241201_12241126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-21241280_13011126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-1211049_107701032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-1211151_117401032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-1211201_122401032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-1211280_130101032.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-21241151_11741105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-21241201_12241105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-21241280_13011105.66666666666671320.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-21241151_11741096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-21241201_12241096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-21241280_13011096.66666666666671311.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-1201049_10770989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-1201151_11740989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-1201201_12240989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-1201280_13010989.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-22251151_11741139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-22251201_12241139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-22251280_13011139.66666666666671354.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-22251151_11741142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-22251201_12241142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-22251280_13011142.66666666666671357.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-18211049_10771030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-18211151_11741030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-18211201_12241030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-18211280_13011030.66666666666671245.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-20231049_10771052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-20231151_11741052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-20231201_12241052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-20231280_13011052.66666666666671267.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-21241151_11741126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-21241201_12241126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-21241280_13011126.66666666666671341.0Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121984_104201032.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120984_10420989.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-1821984_10421030.66666666666671245.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121984_104201032.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120984_10420989.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-1821984_10421030.66666666666671245.0Compositional biasNote=Lys-rich
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121271_35901032.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121461_54601032.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121590_67701032.0DomainPDZ 3
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120271_3590989.0DomainPDZ 1
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120461_5460989.0DomainPDZ 2
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120590_6770989.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121271_35901032.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121461_54601032.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121590_67701032.0DomainPDZ 3
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120271_3590989.0DomainPDZ 1
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120461_5460989.0DomainPDZ 2
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120590_6770989.0DomainPDZ 3


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>2081_PARD3_34558585_NSUN6_18905222_ranked_0.pdbPARD33455858434558585ENST00000377304NSUN6chr1018905222-
MPAPLAARAPESPAAPPRPASSVPASAAPAALGEGRGPARGGGGMKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWI
QVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANM
PLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASH
PMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHEN
LFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAP
RLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPR
GAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREF
LTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMI
QLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRL
PVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLG
IADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGME
TLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIE
KTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDAL
YAQVKKPRNSKPSPVDRKNIKKQQCEAIVGAQCGNAVLRGAHVYAPGIVSASQFMKAGDVISVYSDIKGKCKKGAKEFDGTKVFLGNGIS
ELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVIALDK
IFNKVEKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGMGQRPNMACTWSVKEVASYQPLQRKLFTA
AVQLLKPEGVLVYSTCTITLAENEEQVAWALTKFPCLQLQPQEPQIGGEGMRGAGLSCEQLKQLQRFDPSAVPLPDTDMDSLREARREDM
1552


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
PARD3_pLDDT.png
all structure
all structure
NSUN6_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PARD3
NSUN6


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121935_135601032.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000346874-2124935_13561105.66666666666671320.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000350537-2124935_13561096.66666666666671311.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120935_13560989.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000374788-2225935_13561139.66666666666671354.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000374789-2225935_13561142.66666666666671357.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000374794-1821935_13561030.66666666666671245.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000545260-2023935_13561052.66666666666671267.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000545693-2124935_13561126.66666666666671341.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121935_135601032.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000346874-2124935_13561105.66666666666671320.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000350537-2124935_13561096.66666666666671311.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120935_13560989.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000374788-2225935_13561139.66666666666671354.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000374789-2225935_13561142.66666666666671357.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000374794-1821935_13561030.66666666666671245.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000545260-2023935_13561052.66666666666671267.0FRMD4A
HgenePARD3chr10:34558585chr10:18905222ENST00000545693-2124935_13561126.66666666666671341.0FRMD4A
HgenePARD3chr10:34558584chr10:18905222ENST00000340077-121712_93601032.0PRKCI and PRKCZ
HgenePARD3chr10:34558584chr10:18905222ENST00000374776-120712_9360989.0PRKCI and PRKCZ
HgenePARD3chr10:34558585chr10:18905222ENST00000340077-121712_93601032.0PRKCI and PRKCZ
HgenePARD3chr10:34558585chr10:18905222ENST00000374776-120712_9360989.0PRKCI and PRKCZ


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Related Drugs to PARD3-NSUN6


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PARD3-NSUN6


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource