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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PLEC-JPH1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PLEC-JPH1
FusionPDB ID: 66131
FusionGDB2.0 ID: 66131
HgeneTgene
Gene symbol

PLEC

JPH1

Gene ID

5339

56704

Gene nameplectinjunctophilin 1
SynonymsEBS1|EBSMD|EBSND|EBSO|EBSOG|EBSPA|HD1|LGMD2Q|LGMDR17|PCN|PLEC1|PLEC1b|PLTNCMT2K|JP-1|JP1
Cytomap

8q24.3

8q21.11

Type of geneprotein-codingprotein-coding
Descriptionplectinhemidesmosomal protein 1plectin 1, intermediate filament binding protein 500kDajunctophilin-1junctophilin type 1
Modification date2020031320200328
UniProtAcc

PLEC

Q9HDC5

Ensembl transtripts involved in fusion geneENST idsENST00000322810, ENST00000345136, 
ENST00000354589, ENST00000354958, 
ENST00000356346, ENST00000357649, 
ENST00000398774, ENST00000436759, 
ENST00000527096, 		ENST00000518195, 
ENST00000342232, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score26 X 19 X 12=59283 X 2 X 3=18
# samples 264
** MAII scorelog2(26/5928*10)=-4.51096191927738
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PLEC [Title/Abstract] AND JPH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PLEC(145012319)-JPH1(75171738), # samples:3
Anticipated loss of major functional domain due to fusion event.PLEC-JPH1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEC-JPH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEC-JPH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePLEC

GO:0031581

hemidesmosome assembly

12482924


check buttonFusion gene breakpoints across PLEC (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across JPH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-AB2E-01APLECchr8

145012319

-JPH1chr8

75171738

-
ChimerDB4SARCTCGA-DX-AB2G-01APLECchr8

145012319

-JPH1chr8

75171738

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000436759PLECchr8145012319-ENST00000342232JPH1chr875171738-3581383541229391

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000436759ENST00000342232PLECchr8145012319-JPH1chr875171738-0.0010020560.998998

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>66131_66131_1_PLEC-JPH1_PLEC_chr8_145012319_ENST00000436759_JPH1_chr8_75171738_ENST00000342232_length(amino acids)=391AA_BP=110
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQMSGIVCRRKPSPSGSTSTSSRPRGTSVTCMK
TSAMATTSSPCWRSSRGTAWTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPK
ESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPN
PSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDSCPALE

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:145012319/chr8:75171738)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PLEC

PLEC

JPH1

Q9HDC5

4684FUNCTION: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216640_660379.66666666666671079.3333333333333TransmembraneHelical%3B Anchor for type IV membrane protein

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3321469_2756225.04685.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3321469_275688.04548.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3321469_275688.04548.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3321469_275666.04526.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3321469_275674.04534.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3321469_275692.04552.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3321469_275656.04516.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4331469_2756115.04575.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3321469_2756115.04571.0Coiled coilOntology_term=ECO:0000255
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332179_282225.04685.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332295_400225.04685.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332941_998225.04685.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332179_28288.04548.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332295_40088.04548.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332941_99888.04548.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332179_28288.04548.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332295_40088.04548.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332941_99888.04548.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332179_28266.04526.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332295_40066.04526.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332941_99866.04526.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332179_28274.04534.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332295_40074.04534.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332941_99874.04534.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332179_28292.04552.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332295_40092.04552.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332941_99892.04552.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332179_28256.04516.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332295_40056.04516.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332941_99856.04516.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433179_282115.04575.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433295_400115.04575.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433941_998115.04575.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332179_282115.04571.0DomainCalponin-homology (CH) 1
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332295_400115.04571.0DomainCalponin-homology (CH) 2
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332941_998115.04571.0DomainSH3
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3321471_2755225.04685.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332175_400225.04685.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3321_1470225.04685.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322756_4684225.04685.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324250_4300225.04685.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324625_4640225.04685.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3321471_275588.04548.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332175_40088.04548.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3321_147088.04548.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322756_468488.04548.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324250_430088.04548.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324625_464088.04548.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3321471_275588.04548.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332175_40088.04548.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3321_147088.04548.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322756_468488.04548.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324250_430088.04548.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324625_464088.04548.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3321471_275566.04526.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332175_40066.04526.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3321_147066.04526.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322756_468466.04526.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324250_430066.04526.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324625_464066.04526.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3321471_275574.04534.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332175_40074.04534.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3321_147074.04534.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322756_468474.04534.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324250_430074.04534.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324625_464074.04534.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3321471_275592.04552.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332175_40092.04552.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3321_147092.04552.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322756_468492.04552.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324250_430092.04552.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324625_464092.04552.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3321471_275556.04516.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332175_40056.04516.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3321_147056.04516.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322756_468456.04516.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324250_430056.04516.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324625_464056.04516.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4331471_2755115.04575.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433175_400115.04575.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4331_1470115.04575.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332756_4684115.04575.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334250_4300115.04575.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334625_4640115.04575.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3321471_2755115.04571.0RegionNote=Central fibrous rod domain
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332175_400115.04571.0RegionNote=Actin-binding
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3321_1470115.04571.0RegionNote=Globular 1
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322756_4684115.04571.0RegionNote=Globular 2
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324250_4300115.04571.0RegionBinding to intermediate filaments
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324625_4640115.04571.0RegionNote=4 X 4 AA tandem repeats of G-S-R-X
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3321315_1415225.04685.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322826_2863225.04685.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322864_2901225.04685.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322902_2939225.04685.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322940_2977225.04685.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3322981_3015225.04685.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323116_3153225.04685.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323154_3191225.04685.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323192_3229225.04685.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323230_3267225.04685.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323268_3305225.04685.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323306_3343225.04685.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323485_3522225.04685.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323523_3560225.04685.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323561_3598225.04685.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323599_3636225.04685.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323640_3674225.04685.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323820_3857225.04685.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323858_3895225.04685.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323896_3933225.04685.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323934_3971225.04685.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3323975_4008225.04685.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324063_4100225.04685.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324101_4138225.04685.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324139_4176225.04685.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324177_4214225.04685.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324218_4252225.04685.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324265_4305225.04685.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324319_4356225.04685.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324408_4445225.04685.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324446_4483225.04685.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324484_4521225.04685.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324522_4559225.04685.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000322810-3324560_4597225.04685.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332645_710225.04685.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332740_824225.04685.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000322810-332837_930225.04685.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3321315_141588.04548.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322826_286388.04548.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322864_290188.04548.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322902_293988.04548.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322940_297788.04548.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3322981_301588.04548.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323116_315388.04548.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323154_319188.04548.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323192_322988.04548.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323230_326788.04548.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323268_330588.04548.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323306_334388.04548.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323485_352288.04548.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323523_356088.04548.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323561_359888.04548.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323599_363688.04548.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323640_367488.04548.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323820_385788.04548.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323858_389588.04548.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323896_393388.04548.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323934_397188.04548.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3323975_400888.04548.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324063_410088.04548.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324101_413888.04548.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324139_417688.04548.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324177_421488.04548.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324218_425288.04548.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324265_430588.04548.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324319_435688.04548.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324408_444588.04548.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324446_448388.04548.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324484_452188.04548.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324522_455988.04548.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000345136-3324560_459788.04548.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332645_71088.04548.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332740_82488.04548.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000345136-332837_93088.04548.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3321315_141588.04548.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322826_286388.04548.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322864_290188.04548.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322902_293988.04548.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322940_297788.04548.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3322981_301588.04548.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323116_315388.04548.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323154_319188.04548.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323192_322988.04548.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323230_326788.04548.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323268_330588.04548.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323306_334388.04548.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323485_352288.04548.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323523_356088.04548.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323561_359888.04548.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323599_363688.04548.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323640_367488.04548.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323820_385788.04548.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323858_389588.04548.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323896_393388.04548.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323934_397188.04548.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3323975_400888.04548.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324063_410088.04548.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324101_413888.04548.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324139_417688.04548.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324177_421488.04548.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324218_425288.04548.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324265_430588.04548.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324319_435688.04548.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324408_444588.04548.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324446_448388.04548.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324484_452188.04548.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324522_455988.04548.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000354589-3324560_459788.04548.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332645_71088.04548.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332740_82488.04548.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000354589-332837_93088.04548.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3321315_141566.04526.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322826_286366.04526.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322864_290166.04526.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322902_293966.04526.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322940_297766.04526.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3322981_301566.04526.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323116_315366.04526.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323154_319166.04526.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323192_322966.04526.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323230_326766.04526.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323268_330566.04526.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323306_334366.04526.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323485_352266.04526.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323523_356066.04526.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323561_359866.04526.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323599_363666.04526.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323640_367466.04526.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323820_385766.04526.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323858_389566.04526.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323896_393366.04526.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323934_397166.04526.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3323975_400866.04526.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324063_410066.04526.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324101_413866.04526.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324139_417666.04526.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324177_421466.04526.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324218_425266.04526.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324265_430566.04526.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324319_435666.04526.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324408_444566.04526.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324446_448366.04526.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324484_452166.04526.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324522_455966.04526.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000354958-3324560_459766.04526.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332645_71066.04526.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332740_82466.04526.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000354958-332837_93066.04526.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3321315_141574.04534.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322826_286374.04534.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322864_290174.04534.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322902_293974.04534.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322940_297774.04534.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3322981_301574.04534.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323116_315374.04534.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323154_319174.04534.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323192_322974.04534.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323230_326774.04534.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323268_330574.04534.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323306_334374.04534.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323485_352274.04534.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323523_356074.04534.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323561_359874.04534.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323599_363674.04534.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323640_367474.04534.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323820_385774.04534.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323858_389574.04534.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323896_393374.04534.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323934_397174.04534.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3323975_400874.04534.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324063_410074.04534.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324101_413874.04534.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324139_417674.04534.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324177_421474.04534.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324218_425274.04534.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324265_430574.04534.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324319_435674.04534.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324408_444574.04534.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324446_448374.04534.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324484_452174.04534.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324522_455974.04534.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000356346-3324560_459774.04534.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332645_71074.04534.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332740_82474.04534.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000356346-332837_93074.04534.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3321315_141592.04552.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322826_286392.04552.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322864_290192.04552.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322902_293992.04552.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322940_297792.04552.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3322981_301592.04552.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323116_315392.04552.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323154_319192.04552.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323192_322992.04552.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323230_326792.04552.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323268_330592.04552.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323306_334392.04552.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323485_352292.04552.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323523_356092.04552.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323561_359892.04552.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323599_363692.04552.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323640_367492.04552.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323820_385792.04552.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323858_389592.04552.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323896_393392.04552.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323934_397192.04552.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3323975_400892.04552.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324063_410092.04552.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324101_413892.04552.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324139_417692.04552.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324177_421492.04552.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324218_425292.04552.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324265_430592.04552.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324319_435692.04552.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324408_444592.04552.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324446_448392.04552.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324484_452192.04552.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324522_455992.04552.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000357649-3324560_459792.04552.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332645_71092.04552.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332740_82492.04552.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000357649-332837_93092.04552.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3321315_141556.04516.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322826_286356.04516.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322864_290156.04516.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322902_293956.04516.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322940_297756.04516.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3322981_301556.04516.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323116_315356.04516.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323154_319156.04516.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323192_322956.04516.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323230_326756.04516.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323268_330556.04516.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323306_334356.04516.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323485_352256.04516.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323523_356056.04516.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323561_359856.04516.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323599_363656.04516.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323640_367456.04516.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323820_385756.04516.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323858_389556.04516.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323896_393356.04516.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323934_397156.04516.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3323975_400856.04516.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324063_410056.04516.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324101_413856.04516.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324139_417656.04516.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324177_421456.04516.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324218_425256.04516.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324265_430556.04516.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324319_435656.04516.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324408_444556.04516.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324446_448356.04516.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324484_452156.04516.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324522_455956.04516.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000398774-3324560_459756.04516.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332645_71056.04516.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332740_82456.04516.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000398774-332837_93056.04516.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4331315_1415115.04575.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332826_2863115.04575.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332864_2901115.04575.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332902_2939115.04575.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332940_2977115.04575.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4332981_3015115.04575.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333116_3153115.04575.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333154_3191115.04575.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333192_3229115.04575.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333230_3267115.04575.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333268_3305115.04575.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333306_3343115.04575.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333485_3522115.04575.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333523_3560115.04575.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333561_3598115.04575.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333599_3636115.04575.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333640_3674115.04575.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333820_3857115.04575.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333858_3895115.04575.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333896_3933115.04575.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333934_3971115.04575.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4333975_4008115.04575.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334063_4100115.04575.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334101_4138115.04575.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334139_4176115.04575.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334177_4214115.04575.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334218_4252115.04575.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334265_4305115.04575.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334319_4356115.04575.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334408_4445115.04575.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334446_4483115.04575.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334484_4521115.04575.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334522_4559115.04575.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000436759-4334560_4597115.04575.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433645_710115.04575.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433740_824115.04575.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000436759-433837_930115.04575.0RepeatNote=Spectrin 3
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3321315_1415115.04571.0RepeatNote=Spectrin 4
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322826_2863115.04571.0RepeatNote=Plectin 1
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322864_2901115.04571.0RepeatNote=Plectin 2
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322902_2939115.04571.0RepeatNote=Plectin 3
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322940_2977115.04571.0RepeatNote=Plectin 4
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3322981_3015115.04571.0RepeatNote=Plectin 5
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323116_3153115.04571.0RepeatNote=Plectin 6
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323154_3191115.04571.0RepeatNote=Plectin 7
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323192_3229115.04571.0RepeatNote=Plectin 8
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323230_3267115.04571.0RepeatNote=Plectin 9
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323268_3305115.04571.0RepeatNote=Plectin 10
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323306_3343115.04571.0RepeatNote=Plectin 11
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323485_3522115.04571.0RepeatNote=Plectin 12
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323523_3560115.04571.0RepeatNote=Plectin 13
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323561_3598115.04571.0RepeatNote=Plectin 14
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323599_3636115.04571.0RepeatNote=Plectin 15
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323640_3674115.04571.0RepeatNote=Plectin 16
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323820_3857115.04571.0RepeatNote=Plectin 17
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323858_3895115.04571.0RepeatNote=Plectin 18
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323896_3933115.04571.0RepeatNote=Plectin 19
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323934_3971115.04571.0RepeatNote=Plectin 20
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3323975_4008115.04571.0RepeatNote=Plectin 21
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324063_4100115.04571.0RepeatNote=Plectin 22
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324101_4138115.04571.0RepeatNote=Plectin 23
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324139_4176115.04571.0RepeatNote=Plectin 24
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324177_4214115.04571.0RepeatNote=Plectin 25
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324218_4252115.04571.0RepeatNote=Plectin 26
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324265_4305115.04571.0RepeatNote=Plectin 27
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324319_4356115.04571.0RepeatNote=Plectin 28
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324408_4445115.04571.0RepeatNote=Plectin 29
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324446_4483115.04571.0RepeatNote=Plectin 30
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324484_4521115.04571.0RepeatNote=Plectin 31
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324522_4559115.04571.0RepeatNote=Plectin 32
HgenePLECchr8:145012319chr8:75171738ENST00000527096-3324560_4597115.04571.0RepeatNote=Plectin 33
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332645_710115.04571.0RepeatNote=Spectrin 1
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332740_824115.04571.0RepeatNote=Spectrin 2
HgenePLECchr8:145012319chr8:75171738ENST00000527096-332837_930115.04571.0RepeatNote=Spectrin 3
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216226_258379.66666666666671079.3333333333333Compositional biasNote=Ser-rich
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216359_409379.66666666666671079.3333333333333Compositional biasNote=Ala-rich
TgeneJPH1chr8:145012319chr8:75171738ENST00000342232163_142379.66666666666671079.3333333333333Compositional biasNote=Gly-rich
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216106_128379.66666666666671079.3333333333333RepeatNote=MORN 4
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216129_151379.66666666666671079.3333333333333RepeatNote=MORN 5
TgeneJPH1chr8:145012319chr8:75171738ENST000003422321614_36379.66666666666671079.3333333333333RepeatNote=MORN 1
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216281_303379.66666666666671079.3333333333333RepeatNote=MORN 6
TgeneJPH1chr8:145012319chr8:75171738ENST0000034223216304_326379.66666666666671079.3333333333333RepeatNote=MORN 7
TgeneJPH1chr8:145012319chr8:75171738ENST000003422321638_59379.66666666666671079.3333333333333RepeatNote=MORN 2
TgeneJPH1chr8:145012319chr8:75171738ENST000003422321660_82379.66666666666671079.3333333333333RepeatNote=MORN 3
TgeneJPH1chr8:145012319chr8:75171738ENST00000342232161_639379.66666666666671079.3333333333333Topological domainCytoplasmic


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>784_PLEC_145012319_JPH1_75171738_ranked_0.pdbPLEC145012319145012319ENST00000342232JPH1chr875171738-
MRSGQSLKMSPMEAVARPALGTHCPGTLGKRSGAGAAGVALGATGVSWTQLSGRSFASQMSGIVCRRKPSPSGSTSTSSRPRGTSVTCMK
TSAMATTSSPCWRSSRGTAWTAHARAKADAADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEGVDAKENPEEKVPEKPPTPK
ESPHFYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGARLNQDKRSVADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPN
PSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSALVHKPSANKWSPSKSVTKPVAKESKAEPKAKKSELAIPKNPASNDSCPALE
391


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
PLEC_pLDDT.png
all structure
all structure
JPH1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PLEC
JPH1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to PLEC-JPH1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PLEC-JPH1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource