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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ARL8B-ITPR1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ARL8B-ITPR1
FusionPDB ID: 6635
FusionGDB2.0 ID: 6635
HgeneTgene
Gene symbol

ARL8B

ITPR1

Gene ID

55207

3708

Gene nameADP ribosylation factor like GTPase 8Binositol 1,4,5-trisphosphate receptor type 1
SynonymsARL10C|Gie1ACV|CLA4|INSP3R1|IP3R|IP3R1|PPP1R94|SCA15|SCA16|SCA29
Cytomap

3p26.1

3p26.1

Type of geneprotein-codingprotein-coding
DescriptionADP-ribosylation factor-like protein 8BADP-ribosylation factor-like 10CADP-ribosylation factor-like 8BADP-ribosylation factor-like protein 10Cnovel small G protein indispensable for equal chromosome segregation 1inositol 1,4,5-trisphosphate receptor type 1IP3 receptorIP3R 1inositol 1,4,5-triphosphate receptor, type 1protein phosphatase 1, regulatory subunit 94type 1 InsP3 receptortype 1 inositol 1,4,5-trisphosphate receptor
Modification date2020031320200327
UniProtAcc

Q9NVJ2

Q14643

Ensembl transtripts involved in fusion geneENST idsENST00000256496, ENST00000419534, 
ENST00000468010, 		ENST00000463980, 
ENST00000443694, ENST00000544951, 
ENST00000302640, ENST00000354582, 
ENST00000357086, ENST00000423119, 
ENST00000456211, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score4 X 1 X 7=289 X 13 X 8=936
# samples 916
** MAII scorelog2(9/28*10)=1.68449817427207
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(16/936*10)=-2.54843662469604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ARL8B [Title/Abstract] AND ITPR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ARL8B(5164273)-ITPR1(4808214), # samples:3
Anticipated loss of major functional domain due to fusion event.ARL8B-ITPR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARL8B-ITPR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARL8B-ITPR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARL8B-ITPR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARL8B-ITPR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneITPR1

GO:0001666

response to hypoxia

19120137

TgeneITPR1

GO:0050849

negative regulation of calcium-mediated signaling

16793548


check buttonFusion gene breakpoints across ARL8B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ITPR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-K4-A83P-01AARL8Bchr3

5164273

-ITPR1chr3

4808214

+
ChimerDB4BLCATCGA-K4-A83P-01AARL8Bchr3

5164273

+ITPR1chr3

4808214

+
ChimerDB4BRCATCGA-A8-A07O-01AARL8Bchr3

5164273

+ITPR1chr3

4878458

+
ChimerDB4CESCTCGA-EA-A50E-01AARL8Bchr3

5164273

-ITPR1chr3

4887823

+
ChimerDB4CESCTCGA-EA-A50E-01AARL8Bchr3

5164273

+ITPR1chr3

4887823

+
ChimerDB4CESCTCGA-EA-A50EARL8Bchr3

5164273

+ITPR1chr3

4887822

+
ChimerDB4CESCTCGA-JW-A5VJ-01AARL8Bchr3

5164273

-ITPR1chr3

4808214

+
ChimerDB4OVTCGA-61-1738-01AARL8Bchr3

5164273

+ITPR1chr3

4722237

+
ChimerDB4OVTCGA-61-1738ARL8Bchr3

5164273

+ITPR1chr3

4725069

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000256496ARL8Bchr35164273+ENST00000456211ITPR1chr34887822+18333693950132
ENST00000256496ARL8Bchr35164273+ENST00000357086ITPR1chr34887822+18333693950132
ENST00000256496ARL8Bchr35164273+ENST00000443694ITPR1chr34887822+16263693950132
ENST00000419534ARL8Bchr35164273+ENST00000456211ITPR1chr34887822+175729325387120
ENST00000419534ARL8Bchr35164273+ENST00000357086ITPR1chr34887822+175729325387120
ENST00000419534ARL8Bchr35164273+ENST00000443694ITPR1chr34887822+155029325387120
ENST00000256496ARL8Bchr35164273+ENST00000423119ITPR1chr34725069+697936924653631705
ENST00000419534ARL8Bchr35164273+ENST00000423119ITPR1chr34725069+690329317052871705
ENST00000256496ARL8Bchr35164273+ENST00000302640ITPR1chr34808214+47173692463101951
ENST00000256496ARL8Bchr35164273+ENST00000354582ITPR1chr34808214+47173692463101951
ENST00000256496ARL8Bchr35164273+ENST00000423119ITPR1chr34808214+47173692463101951
ENST00000256496ARL8Bchr35164273+ENST00000456211ITPR1chr34808214+44793692463101951
ENST00000256496ARL8Bchr35164273+ENST00000357086ITPR1chr34808214+44793692463101951
ENST00000419534ARL8Bchr35164273+ENST00000302640ITPR1chr34808214+46412931703025951
ENST00000419534ARL8Bchr35164273+ENST00000354582ITPR1chr34808214+46412931703025951
ENST00000419534ARL8Bchr35164273+ENST00000423119ITPR1chr34808214+46412931703025951
ENST00000419534ARL8Bchr35164273+ENST00000456211ITPR1chr34808214+44032931703025951
ENST00000419534ARL8Bchr35164273+ENST00000357086ITPR1chr34808214+44032931703025951
ENST00000256496ARL8Bchr35164273+ENST00000302640ITPR1chr34878458+2233369246617123
ENST00000256496ARL8Bchr35164273+ENST00000354582ITPR1chr34878458+2233369246617123
ENST00000256496ARL8Bchr35164273+ENST00000423119ITPR1chr34878458+2233369246617123
ENST00000256496ARL8Bchr35164273+ENST00000456211ITPR1chr34878458+19953694812160
ENST00000256496ARL8Bchr35164273+ENST00000357086ITPR1chr34878458+19953694812160
ENST00000256496ARL8Bchr35164273+ENST00000544951ITPR1chr34878458+11033694812160
ENST00000256496ARL8Bchr35164273+ENST00000443694ITPR1chr34878458+17883694812160
ENST00000419534ARL8Bchr35164273+ENST00000302640ITPR1chr34878458+2157293170541123
ENST00000419534ARL8Bchr35164273+ENST00000354582ITPR1chr34878458+2157293170541123
ENST00000419534ARL8Bchr35164273+ENST00000423119ITPR1chr34878458+2157293170541123
ENST00000419534ARL8Bchr35164273+ENST00000456211ITPR1chr34878458+19192934051135
ENST00000419534ARL8Bchr35164273+ENST00000357086ITPR1chr34878458+19192934051135
ENST00000419534ARL8Bchr35164273+ENST00000544951ITPR1chr34878458+10272934051135
ENST00000419534ARL8Bchr35164273+ENST00000443694ITPR1chr34878458+17122934051135
ENST00000256496ARL8Bchr35164273+ENST00000456211ITPR1chr34887823+18333693950132
ENST00000256496ARL8Bchr35164273+ENST00000357086ITPR1chr34887823+18333693950132
ENST00000256496ARL8Bchr35164273+ENST00000443694ITPR1chr34887823+16263693950132
ENST00000419534ARL8Bchr35164273+ENST00000456211ITPR1chr34887823+175729325387120
ENST00000419534ARL8Bchr35164273+ENST00000357086ITPR1chr34887823+175729325387120
ENST00000419534ARL8Bchr35164273+ENST00000443694ITPR1chr34887823+155029325387120
ENST00000256496ARL8Bchr35164273+ENST00000302640ITPR1chr34722237+729436924656781810
ENST00000256496ARL8Bchr35164273+ENST00000354582ITPR1chr34722237+724936924656331795
ENST00000256496ARL8Bchr35164273+ENST00000423119ITPR1chr34722237+717736924655611771
ENST00000256496ARL8Bchr35164273+ENST00000456211ITPR1chr34722237+693936924655611771
ENST00000256496ARL8Bchr35164273+ENST00000357086ITPR1chr34722237+693936924655611771
ENST00000419534ARL8Bchr35164273+ENST00000302640ITPR1chr34722237+721829317056021810
ENST00000419534ARL8Bchr35164273+ENST00000354582ITPR1chr34722237+717329317055571795
ENST00000419534ARL8Bchr35164273+ENST00000423119ITPR1chr34722237+710129317054851771
ENST00000419534ARL8Bchr35164273+ENST00000456211ITPR1chr34722237+686329317054851771
ENST00000419534ARL8Bchr35164273+ENST00000357086ITPR1chr34722237+686329317054851771

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000256496ENST00000456211ARL8Bchr35164273+ITPR1chr34887822+0.356597420.6434026
ENST00000256496ENST00000357086ARL8Bchr35164273+ITPR1chr34887822+0.356597420.6434026
ENST00000256496ENST00000443694ARL8Bchr35164273+ITPR1chr34887822+0.320485740.6795142
ENST00000419534ENST00000456211ARL8Bchr35164273+ITPR1chr34887822+0.207593750.7924062
ENST00000419534ENST00000357086ARL8Bchr35164273+ITPR1chr34887822+0.207593750.7924062
ENST00000419534ENST00000443694ARL8Bchr35164273+ITPR1chr34887822+0.180201280.81979865
ENST00000256496ENST00000423119ARL8Bchr35164273+ITPR1chr34725069+0.0005967430.99940324
ENST00000419534ENST00000423119ARL8Bchr35164273+ITPR1chr34725069+0.000541640.9994584
ENST00000256496ENST00000302640ARL8Bchr35164273+ITPR1chr34808214+0.0001075640.9998925
ENST00000256496ENST00000354582ARL8Bchr35164273+ITPR1chr34808214+0.0001075640.9998925
ENST00000256496ENST00000423119ARL8Bchr35164273+ITPR1chr34808214+0.0001075640.9998925
ENST00000256496ENST00000456211ARL8Bchr35164273+ITPR1chr34808214+0.0001262940.99987364
ENST00000256496ENST00000357086ARL8Bchr35164273+ITPR1chr34808214+0.0001262940.99987364
ENST00000419534ENST00000302640ARL8Bchr35164273+ITPR1chr34808214+0.0001023930.9998976
ENST00000419534ENST00000354582ARL8Bchr35164273+ITPR1chr34808214+0.0001023930.9998976
ENST00000419534ENST00000423119ARL8Bchr35164273+ITPR1chr34808214+0.0001023930.9998976
ENST00000419534ENST00000456211ARL8Bchr35164273+ITPR1chr34808214+0.0001198050.9998802
ENST00000419534ENST00000357086ARL8Bchr35164273+ITPR1chr34808214+0.0001198050.9998802
ENST00000256496ENST00000302640ARL8Bchr35164273+ITPR1chr34878458+0.00814730.9918527
ENST00000256496ENST00000354582ARL8Bchr35164273+ITPR1chr34878458+0.00814730.9918527
ENST00000256496ENST00000423119ARL8Bchr35164273+ITPR1chr34878458+0.00814730.9918527
ENST00000256496ENST00000456211ARL8Bchr35164273+ITPR1chr34878458+0.0084767540.99152327
ENST00000256496ENST00000357086ARL8Bchr35164273+ITPR1chr34878458+0.0084767540.99152327
ENST00000256496ENST00000544951ARL8Bchr35164273+ITPR1chr34878458+0.0094258760.9905742
ENST00000256496ENST00000443694ARL8Bchr35164273+ITPR1chr34878458+0.0081551690.99184483
ENST00000419534ENST00000302640ARL8Bchr35164273+ITPR1chr34878458+0.0066809860.99331903
ENST00000419534ENST00000354582ARL8Bchr35164273+ITPR1chr34878458+0.0066809860.99331903
ENST00000419534ENST00000423119ARL8Bchr35164273+ITPR1chr34878458+0.0066809860.99331903
ENST00000419534ENST00000456211ARL8Bchr35164273+ITPR1chr34878458+0.0071739610.9928261
ENST00000419534ENST00000357086ARL8Bchr35164273+ITPR1chr34878458+0.0071739610.9928261
ENST00000419534ENST00000544951ARL8Bchr35164273+ITPR1chr34878458+0.0085266230.9914733
ENST00000419534ENST00000443694ARL8Bchr35164273+ITPR1chr34878458+0.0081714840.9918285
ENST00000256496ENST00000456211ARL8Bchr35164273+ITPR1chr34887823+0.356597420.6434026
ENST00000256496ENST00000357086ARL8Bchr35164273+ITPR1chr34887823+0.356597420.6434026
ENST00000256496ENST00000443694ARL8Bchr35164273+ITPR1chr34887823+0.320485740.6795142
ENST00000419534ENST00000456211ARL8Bchr35164273+ITPR1chr34887823+0.207593750.7924062
ENST00000419534ENST00000357086ARL8Bchr35164273+ITPR1chr34887823+0.207593750.7924062
ENST00000419534ENST00000443694ARL8Bchr35164273+ITPR1chr34887823+0.180201280.81979865
ENST00000256496ENST00000302640ARL8Bchr35164273+ITPR1chr34722237+0.0006724750.99932754
ENST00000256496ENST00000354582ARL8Bchr35164273+ITPR1chr34722237+0.0006557760.99934417
ENST00000256496ENST00000423119ARL8Bchr35164273+ITPR1chr34722237+0.0006226040.9993774
ENST00000256496ENST00000456211ARL8Bchr35164273+ITPR1chr34722237+0.0007293380.9992706
ENST00000256496ENST00000357086ARL8Bchr35164273+ITPR1chr34722237+0.0007293380.9992706
ENST00000419534ENST00000302640ARL8Bchr35164273+ITPR1chr34722237+0.0006108490.9993892
ENST00000419534ENST00000354582ARL8Bchr35164273+ITPR1chr34722237+0.0005954430.99940455
ENST00000419534ENST00000423119ARL8Bchr35164273+ITPR1chr34722237+0.0005649830.999435
ENST00000419534ENST00000456211ARL8Bchr35164273+ITPR1chr34722237+0.0006584670.99934155
ENST00000419534ENST00000357086ARL8Bchr35164273+ITPR1chr34722237+0.0006584670.99934155

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>6635_6635_1_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4722237_ENST00000302640_length(amino acids)=1810AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRP
SGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQ
HSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTF
RREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGL
LGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAE
RILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVR
LDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLL
VAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFT
RGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILE
VDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEE
PLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKV
KDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPP

--------------------------------------------------------------

>6635_6635_2_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4722237_ENST00000354582_length(amino acids)=1795AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPL
SAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEK
FFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEG
TQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQ
TLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVI
KKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSI
CEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTL
EPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYH
LLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGE
SLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFF
MVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAE

--------------------------------------------------------------

>6635_6635_3_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4722237_ENST00000357086_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_4_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4722237_ENST00000423119_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGRKENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_5_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4722237_ENST00000456211_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_6_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4725069_ENST00000423119_length(amino acids)=1705AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVL
QAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLS
KLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQ
HIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDR
MDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFL
VDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAK
SRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPEL
LFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPL
SAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEK
FFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEG
TQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQ
TLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVI
KKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSI
CEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTL
EPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYH
LLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGE
SLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFF
MVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAE

--------------------------------------------------------------

>6635_6635_7_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4808214_ENST00000302640_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_8_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4808214_ENST00000354582_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_9_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4808214_ENST00000357086_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_10_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4808214_ENST00000423119_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_11_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4808214_ENST00000456211_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_12_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000302640_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_13_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000354582_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_14_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000357086_length(amino acids)=160AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_15_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000423119_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_16_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000443694_length(amino acids)=160AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_17_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000456211_length(amino acids)=160AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_18_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4878458_ENST00000544951_length(amino acids)=160AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_19_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887822_ENST00000357086_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_20_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887822_ENST00000443694_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_21_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887822_ENST00000456211_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_22_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887823_ENST00000357086_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_23_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887823_ENST00000443694_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_24_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000256496_ITPR1_chr3_4887823_ENST00000456211_length(amino acids)=132AA_BP=
MFLLPLFCHRDDIDEGGLARVLQPHERQLHLFLPEERTEPVQQAGDERQHDGGRERERTGGRTSGGVDDFHTSGPPPGPSNGSLVPRRDT

--------------------------------------------------------------

>6635_6635_25_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4722237_ENST00000302640_length(amino acids)=1810AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEELEPSPPLRQLEDHKRGEALRQVLVNRYYGNVRP
SGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQ
HSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTF
RREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGL
LGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAE
RILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVR
LDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLL
VAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFT
RGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILE
VDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEE
PLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKV
KDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPP

--------------------------------------------------------------

>6635_6635_26_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4722237_ENST00000354582_length(amino acids)=1795AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKLISIDELDNAELPPAPDSENATEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPL
SAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEK
FFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEG
TQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQ
TLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVI
KKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSI
CEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTL
EPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYH
LLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGE
SLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFF
MVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAE

--------------------------------------------------------------

>6635_6635_27_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4722237_ENST00000357086_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_28_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4722237_ENST00000423119_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGRKENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_29_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4722237_ENST00000456211_length(amino acids)=1771AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGAL
DFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQD
LDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM
GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHC
IETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGK
NVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYV
TEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHSI
VQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKH
TKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPLSAGGPGKPGGGGGGSGSSSMSRGE
MSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNT
SDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPI
LRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHE
SNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASP
RNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSK
INDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPK
PHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFD
LVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPA
PREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSE
KQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSE

--------------------------------------------------------------

>6635_6635_30_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4725069_ENST00000423119_length(amino acids)=1705AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVL
QAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDETMDGASGENEHKKTEEGNNKPQKHESTSSYNYRVVKEILIRLS
KLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHINLFLNPGILEAVTMQ
HIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDR
MDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFL
VDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAK
SRAIAIPVDLDSQVNNLFLKSHSIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPEL
LFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQVLVNRYYGNVRPSGRRESLTSFGNGPL
SAGGPGKPGGGGGGSGSSSMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEK
FFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEG
TQATADKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQ
TLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVI
KKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSI
CEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTL
EPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYH
LLYLVICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGE
SLASEFLFSDVCRVESGENCSSPAPREELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFF
MVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAE

--------------------------------------------------------------

>6635_6635_31_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4808214_ENST00000302640_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_32_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4808214_ENST00000354582_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_33_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4808214_ENST00000357086_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_34_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4808214_ENST00000423119_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_35_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4808214_ENST00000456211_length(amino acids)=951AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ

--------------------------------------------------------------

>6635_6635_36_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000302640_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_37_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000354582_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_38_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000357086_length(amino acids)=135AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_39_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000423119_length(amino acids)=123AA_BP=41
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGQLS

--------------------------------------------------------------

>6635_6635_40_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000443694_length(amino acids)=135AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_41_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000456211_length(amino acids)=135AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_42_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4878458_ENST00000544951_length(amino acids)=135AA_BP=0
MVDSSFSCRFLSSFCSPSESLLTNDMALILGNQSRFLSAMTLTKVVLPEYCSPTSVSSISSFQKSERNQSSRREMSASMMAAGSENGRED

--------------------------------------------------------------

>6635_6635_43_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887822_ENST00000357086_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

>6635_6635_44_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887822_ENST00000443694_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

>6635_6635_45_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887822_ENST00000456211_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

>6635_6635_46_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887823_ENST00000357086_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

>6635_6635_47_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887823_ENST00000443694_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

>6635_6635_48_ARL8B-ITPR1_ARL8B_chr3_5164273_ENST00000419534_ITPR1_chr3_4887823_ENST00000456211_length(amino acids)=120AA_BP=89
MLPPAGVRPCRAGAPRSRWRVRAEARSCGSRRRRRSSVLPSVLAPGRHHAGAHLPPAGLVPFALLEGRDGADARGAAVLGQDHLRQCHRD

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:5164273/chr3:4808214)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARL8B

Q9NVJ2

ITPR1

Q14643

FUNCTION: Plays a role in lysosome motility (PubMed:16537643, PubMed:25898167). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). May play a role in chromosome segregation (PubMed:15331635). {ECO:0000250|UniProtKB:Q9CQW2, ECO:0000269|PubMed:15331635, ECO:0000269|PubMed:16537643, ECO:0000269|PubMed:25898167}.FUNCTION: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate (PubMed:27108797). Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). {ECO:0000250|UniProtKB:P11881, ECO:0000269|PubMed:27108797}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARL8Bchr3:5164273chr3:4722237ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4725069ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4808214ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4878458ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4887822ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4887823ENST00000256496+171_1941.0187.0IntramembraneNote=Note%3DMediates targeting to membranes
HgeneARL8Bchr3:5164273chr3:4722237ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4725069ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4808214ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4878458ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4887822ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4887823ENST00000256496+1729_3541.0187.0Nucleotide bindingNote=GTP
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612304_2314974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612336_2361974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612383_2405974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612427_2448974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612470_2577974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612599_2758974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592304_2314980.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592336_2361980.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592383_2405980.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592427_2448980.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592470_2577980.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592599_2758980.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592304_2314974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592336_2361974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592383_2405974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592427_2448974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592470_2577974.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592599_2758974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582304_2314965.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582336_2361965.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582383_2405965.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582427_2448965.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582470_2577965.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582599_2758965.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612304_23141038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612336_23611038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612383_24051038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612427_24481038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612470_25771038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612599_27581038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592304_23141044.66666666666672711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592336_23611044.66666666666672711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592383_24051044.66666666666672711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592427_24481044.66666666666672711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592470_25771044.66666666666672711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592599_27581044.66666666666672711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592304_23141038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592336_23611038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592383_24051038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592427_24481038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592470_25771038.66666666666672744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592599_27581038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582304_23141029.66666666666672696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582336_23611029.66666666666672696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582383_24051029.66666666666672696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582427_24481029.66666666666672696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582470_25771029.66666666666672696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582599_27581029.66666666666672696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612304_23141833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612336_23611833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612383_24051833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612427_24481833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612470_25771833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612599_27581833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592304_23141800.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592336_23611800.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592383_24051800.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592427_24481800.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592470_25771800.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592599_27581800.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592304_23141833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592336_23611833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592383_24051833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592427_24481833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592470_25771833.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592599_27581833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582304_23141785.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582336_23611785.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582383_24051785.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582427_24481785.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582470_25771785.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582599_27581785.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612283_2303974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612315_2335974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612362_2382974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612406_2426974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612449_2469974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022612578_2598974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592283_2303980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592315_2335980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592362_2382980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592406_2426980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592449_2469980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623592578_2598980.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592283_2303974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592315_2335974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592362_2382974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592406_2426974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592449_2469974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420592578_2598974.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582283_2303965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582315_2335965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582362_2382965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582406_2426965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582449_2469965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122582578_2598965.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612283_23031038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612315_23351038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612362_23821038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612406_24261038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612449_24691038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024612578_25981038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592283_23031044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592315_23351044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592362_23821044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592406_24261044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592449_24691044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625592578_25981044.66666666666672711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592283_23031038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592315_23351038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592362_23821038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592406_24261038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592449_24691038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422592578_25981038.66666666666672744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582283_23031029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582315_23351029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582362_23821029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582406_24261029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582449_24691029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124582578_25981029.66666666666672696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612283_23031833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612315_23351833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612362_23821833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612406_24261833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612449_24691833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042612578_25981833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592283_23031800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592315_23351800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592362_23821800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592406_24261800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592449_24691800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640592578_25981800.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592283_23031833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592315_23351833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592362_23821833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592406_24261833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592449_24691833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440592578_25981833.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582283_23031785.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582315_23351785.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582362_23821785.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582406_24261785.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582449_24691785.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139582578_25981785.02696.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARL8Bchr3:5164273chr3:4722237ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4722237ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
HgeneARL8Bchr3:5164273chr3:4725069ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4725069ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
HgeneARL8Bchr3:5164273chr3:4808214ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4808214ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
HgeneARL8Bchr3:5164273chr3:4878458ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4878458ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
HgeneARL8Bchr3:5164273chr3:4887822ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4887822ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
HgeneARL8Bchr3:5164273chr3:4887823ENST00000256496+17130_13341.0187.0Nucleotide bindingNote=GTP
HgeneARL8Bchr3:5164273chr3:4887823ENST00000256496+1771_7541.0187.0Nucleotide bindingGTP
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261112_166974.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261173_223974.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261231_287974.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261294_373974.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261379_435974.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359112_166980.02711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359173_223980.02711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359231_287980.02711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359294_373980.02711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359379_435980.02711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059112_166974.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059173_223974.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059231_287974.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059294_373974.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059379_435974.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258112_166965.02696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258173_223965.02696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258231_287965.02696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258294_373965.02696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258379_435965.02696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461112_1661038.66666666666672744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461173_2231038.66666666666672744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461231_2871038.66666666666672744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461294_3731038.66666666666672744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461379_4351038.66666666666672744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559112_1661044.66666666666672711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559173_2231044.66666666666672711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559231_2871044.66666666666672711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559294_3731044.66666666666672711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559379_4351044.66666666666672711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259112_1661038.66666666666672744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259173_2231038.66666666666672744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259231_2871038.66666666666672744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259294_3731038.66666666666672744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259379_4351038.66666666666672744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458112_1661029.66666666666672696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458173_2231029.66666666666672696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458231_2871029.66666666666672696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458294_3731029.66666666666672696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458379_4351029.66666666666672696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261112_1661833.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261173_2231833.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261231_2871833.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261294_3731833.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261379_4351833.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059112_1661800.02711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059173_2231800.02711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059231_2871800.02711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059294_3731800.02711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059379_4351800.02711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059112_1661833.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059173_2231833.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059231_2871833.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059294_3731833.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059379_4351833.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958112_1661785.02696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958173_2231785.02696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958231_2871785.02696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958294_3731785.02696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958379_4351785.02696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861112_1662661.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861173_2232661.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861231_2872661.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861294_3732661.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861379_4352661.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659112_1662628.02711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659173_2232628.02711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659231_2872628.02711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659294_3732628.02711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659379_4352628.02711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659112_1662661.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659173_2232661.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659231_2872661.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659294_3732661.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659379_4352661.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558112_1662613.02696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558173_2232613.02696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558231_2872613.02696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558294_3732613.02696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558379_4352613.02696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961112_1662715.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961173_2232715.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961231_2872715.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961294_3732715.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961379_4352715.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759112_1662682.02711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759173_2232682.02711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759231_2872682.02711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759294_3732682.02711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759379_4352682.02711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759112_1662715.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759173_2232715.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759231_2872715.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759294_3732715.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759379_4352715.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658112_1662667.02696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658173_2232667.02696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658231_2872667.02696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658294_3732667.02696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658379_4352667.02696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961112_1662715.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961173_2232715.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961231_2872715.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961294_3732715.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961379_4352715.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759112_1662682.02711.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759173_2232682.02711.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759231_2872682.02711.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759294_3732682.02711.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759379_4352682.02711.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759112_1662715.02744.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759173_2232715.02744.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759231_2872715.02744.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759294_3732715.02744.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759379_4352715.02744.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658112_1662667.02696.0DomainMIR 1
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658173_2232667.02696.0DomainMIR 2
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658231_2872667.02696.0DomainMIR 3
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658294_3732667.02696.0DomainMIR 4
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658379_4352667.02696.0DomainMIR 5
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261265_269974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261508_511974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000003026402261567_569974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359265_269980.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359508_511980.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000003570862359567_569980.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059265_269974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059508_511974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004436942059567_569974.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258265_269965.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258508_511965.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST000004562112258567_569965.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461265_2691038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461508_5111038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003026402461567_5691038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559265_2691044.66666666666672711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559508_5111044.66666666666672711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000003570862559567_5691044.66666666666672711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259265_2691038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259508_5111038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004436942259567_5691038.66666666666672744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458265_2691029.66666666666672696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458508_5111029.66666666666672696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4725069ENST000004562112458567_5691029.66666666666672696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261265_2691833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261508_5111833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003026404261567_5691833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059265_2691800.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059508_5111800.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000003570864059567_5691800.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059265_2691833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059508_5111833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004436944059567_5691833.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958265_2691785.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958508_5111785.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4808214ENST000004562113958567_5691785.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861265_2692661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861508_5112661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003026405861567_5692661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659265_2692628.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659508_5112628.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000003570865659567_5692628.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659265_2692661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659508_5112661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004436945659567_5692661.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558265_2692613.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558508_5112613.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4878458ENST000004562115558567_5692613.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961265_2692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961508_5112715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003026405961567_5692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759265_2692682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759508_5112682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000003570865759567_5692682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759265_2692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759508_5112715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004436945759567_5692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658265_2692667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658508_5112667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887822ENST000004562115658567_5692667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961265_2692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961508_5112715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003026405961567_5692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759265_2692682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759508_5112682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000003570865759567_5692682.02711.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759265_2692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759508_5112715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004436945759567_5692715.02744.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658265_2692667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658508_5112667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4887823ENST000004562115658567_5692667.02696.0RegionInositol 1%2C4%2C5-trisphosphate binding
TgeneITPR1chr3:5164273chr3:4722237ENST0000030264022611_2282974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000035708623591_2282980.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000044369420591_2282974.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4722237ENST0000045621122581_2282965.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000030264024611_22821038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000035708625591_22821044.66666666666672711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000044369422591_22821038.66666666666672744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4725069ENST0000045621124581_22821029.66666666666672696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000030264042611_22821833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000035708640591_22821800.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000044369440591_22821833.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4808214ENST0000045621139581_22821785.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058611_22822661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612304_23142661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612336_23612661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612383_24052661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612427_24482661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612470_25772661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612599_27582661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656591_22822628.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592304_23142628.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592336_23612628.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592383_24052628.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592427_24482628.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592470_25772628.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592599_27582628.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456591_22822661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592304_23142661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592336_23612661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592383_24052661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592427_24482661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592470_25772661.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592599_27582661.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155581_22822613.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582304_23142613.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582336_23612613.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582383_24052613.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582427_24482613.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582470_25772613.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582599_27582613.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059611_22822715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612304_23142715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612336_23612715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612383_24052715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612427_24482715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612470_25772715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612599_27582715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657591_22822682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592304_23142682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592336_23612682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592383_24052682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592427_24482682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592470_25772682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592599_27582682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457591_22822715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592304_23142715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592336_23612715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592383_24052715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592427_24482715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592470_25772715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592599_27582715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156581_22822667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582304_23142667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582336_23612667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582383_24052667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582427_24482667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582470_25772667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582599_27582667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059611_22822715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612304_23142715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612336_23612715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612383_24052715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612427_24482715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612470_25772715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612599_27582715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657591_22822682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592304_23142682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592336_23612682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592383_24052682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592427_24482682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592470_25772682.02711.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592599_27582682.02711.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457591_22822715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592304_23142715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592336_23612715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592383_24052715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592427_24482715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592470_25772715.02744.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592599_27582715.02744.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156581_22822667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582304_23142667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582336_23612667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582383_24052667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582427_24482667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582470_25772667.02696.0Topological domainLumenal
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582599_27582667.02696.0Topological domainCytoplasmic
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612283_23032661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612315_23352661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612362_23822661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612406_24262661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612449_24692661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612578_25982661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592283_23032628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592315_23352628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592362_23822628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592406_24262628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592449_24692628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592578_25982628.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592283_23032661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592315_23352661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592362_23822661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592406_24262661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592449_24692661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592578_25982661.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582283_23032613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582315_23352613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582362_23822613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582406_24262613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582449_24692613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582578_25982613.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612283_23032715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612315_23352715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612362_23822715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612406_24262715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612449_24692715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612578_25982715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592283_23032682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592315_23352682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592362_23822682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592406_24262682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592449_24692682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592578_25982682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592283_23032715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592315_23352715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592362_23822715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592406_24262715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592449_24692715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592578_25982715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582283_23032667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582315_23352667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582362_23822667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582406_24262667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582449_24692667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582578_25982667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612283_23032715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612315_23352715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612362_23822715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612406_24262715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612449_24692715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612578_25982715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592283_23032682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592315_23352682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592362_23822682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592406_24262682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592449_24692682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592578_25982682.02711.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592283_23032715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592315_23352715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592362_23822715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592406_24262715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592449_24692715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592578_25982715.02744.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582283_23032667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582315_23352667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582362_23822667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582406_24262667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582449_24692667.02696.0TransmembraneHelical
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582578_25982667.02696.0TransmembraneHelical


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>1748_ARL8B_5164273_ITPR1_4808214_ranked_0.pdbARL8B51642735164273ENST00000357086ITPR1chr34808214+
MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIAHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDD
EVDRDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQPGEGTQATADKAKDDLEMSAVITIMQPILRFLQLLCEN
HNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITAL
ILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYIL
AHQLARHNKELQSMLKPGGQVDGDEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSED
LFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIAS
TILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLVICAMGLFVHEFFYSLLLFDLVYREETLLN
VIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETAVPETGESLASEFLFSDVCRVESGENCSSPAPREELVPAEE
TEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKT
TCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQ
951


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
ARL8B_pLDDT.png
all structure
all structure
ITPR1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ARL8B
ITPR1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneITPR1chr3:5164273chr3:4878458ENST0000030264058612472_25372661.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4878458ENST0000035708656592472_25372628.02711.0ERP44
TgeneITPR1chr3:5164273chr3:4878458ENST0000044369456592472_25372661.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4878458ENST0000045621155582472_25372613.02696.0ERP44
TgeneITPR1chr3:5164273chr3:4887822ENST0000030264059612472_25372715.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4887822ENST0000035708657592472_25372682.02711.0ERP44
TgeneITPR1chr3:5164273chr3:4887822ENST0000044369457592472_25372715.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4887822ENST0000045621156582472_25372667.02696.0ERP44
TgeneITPR1chr3:5164273chr3:4887823ENST0000030264059612472_25372715.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4887823ENST0000035708657592472_25372682.02711.0ERP44
TgeneITPR1chr3:5164273chr3:4887823ENST0000044369457592472_25372715.02744.0ERP44
TgeneITPR1chr3:5164273chr3:4887823ENST0000045621156582472_25372667.02696.0ERP44


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Related Drugs to ARL8B-ITPR1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ARL8B-ITPR1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource