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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PPFIA1-ANO1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PPFIA1-ANO1
FusionPDB ID: 67382
FusionGDB2.0 ID: 67382
HgeneTgene
Gene symbol

PPFIA1

ANO1

Gene ID

8500

55107

Gene namePTPRF interacting protein alpha 1anoctamin 1
SynonymsLIP.1|LIP1|LIPRINDOG1|ORAOV2|TAOS2|TMEM16A
Cytomap

11q13.3

11q13.3

Type of geneprotein-codingprotein-coding
Descriptionliprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1anoctamin-1Ca2+-activated Cl- channelanoctamin 1, calcium activated chloride channelcalcium activated chloride channeldiscovered on gastrointestinal stromal tumors protein 1oral cancer overexpressed 2transmembrane protein 16A (eight membrane-spannin
Modification date2020032720200313
UniProtAcc.

Q9NW15

Ensembl transtripts involved in fusion geneENST idsENST00000253925, ENST00000389547, 
ENST00000530548, 		ENST00000525494, 
ENST00000316296, ENST00000398543, 
ENST00000530676, ENST00000538023, 
ENST00000531349, ENST00000355303, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score44 X 20 X 15=1320019 X 28 X 10=5320
# samples 6036
** MAII scorelog2(60/13200*10)=-4.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(36/5320*10)=-3.88535743405888
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PPFIA1 [Title/Abstract] AND ANO1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PPFIA1(70118542)-ANO1(69962564), # samples:3
Anticipated loss of major functional domain due to fusion event.PPFIA1-ANO1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PPFIA1-ANO1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneANO1

GO:0006812

cation transport

22946059


check buttonFusion gene breakpoints across PPFIA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ANO1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-GV-A3QK-01BPPFIA1chr11

70118542

+ANO1chr11

69962564

+
ChimerDB4CESCTCGA-IR-A3LA-01APPFIA1chr11

70118541

+ANO1chr11

69962563

+
ChimerDB4CESCTCGA-IR-A3LA-01APPFIA1chr11

70118542

-ANO1chr11

69962564

+
ChimerDB4CESCTCGA-IR-A3LA-01APPFIA1chr11

70118542

+ANO1chr11

69962564

+
ChimerDB4CESCTCGA-IR-A3LAPPFIA1chr11

70118542

+ANO1chr11

69962563

+
ChimerDB4SKCMTCGA-D3-A2J6-06APPFIA1chr11

70118542

-ANO1chr11

69933858

+
ChimerDB4SKCMTCGA-D3-A2J6-06APPFIA1chr11

70118542

+ANO1chr11

69933858

+
ChimerDB4STADTCGA-VQ-A91Y-01APPFIA1chr11

70118542

-ANO1chr11

70016993

+
ChimerDB4STADTCGA-VQ-A91Y-01APPFIA1chr11

70118542

+ANO1chr11

70016993

+
ChimerDB4STADTCGA-VQ-A91YPPFIA1chr11

70118542

+ANO1chr11

70016992

+
ChimerDB4STADTCGA-VQ-AA6G-01APPFIA1chr11

70118542

-ANO1chr11

70007267

+
ChimerDB4STADTCGA-VQ-AA6GPPFIA1chr11

70118542

+ANO1chr11

70007266

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000253925PPFIA1chr1170118542+ENST00000355303ANO1chr1169962563+4109479652584839
ENST00000253925PPFIA1chr1170118542+ENST00000398543ANO1chr1169962563+4018479652494809
ENST00000253925PPFIA1chr1170118542+ENST00000538023ANO1chr1169962563+4108479652584839
ENST00000253925PPFIA1chr1170118542+ENST00000316296ANO1chr1169962563+1721479651636523
ENST00000253925PPFIA1chr1170118542+ENST00000530676ANO1chr1169962563+2772479652494809
ENST00000253925PPFIA1chr1170118542+ENST00000531349ANO1chr1169962563+3755479652506813
ENST00000389547PPFIA1chr1170118542+ENST00000355303ANO1chr1169962563+4092462482567839
ENST00000389547PPFIA1chr1170118542+ENST00000398543ANO1chr1169962563+4001462482477809
ENST00000389547PPFIA1chr1170118542+ENST00000538023ANO1chr1169962563+4091462482567839
ENST00000389547PPFIA1chr1170118542+ENST00000316296ANO1chr1169962563+1704462481619523
ENST00000389547PPFIA1chr1170118542+ENST00000530676ANO1chr1169962563+2755462482477809
ENST00000389547PPFIA1chr1170118542+ENST00000531349ANO1chr1169962563+3738462482489813
ENST00000253925PPFIA1chr1170118542+ENST00000355303ANO1chr1170007266+3386479651861598
ENST00000253925PPFIA1chr1170118542+ENST00000398543ANO1chr1170007266+3385479651861598
ENST00000253925PPFIA1chr1170118542+ENST00000538023ANO1chr1170007266+3385479651861598
ENST00000253925PPFIA1chr1170118542+ENST00000316296ANO1chr1170007266+1088479651003312
ENST00000253925PPFIA1chr1170118542+ENST00000530676ANO1chr1170007266+2139479651861598
ENST00000253925PPFIA1chr1170118542+ENST00000531349ANO1chr1170007266+3110479651861598
ENST00000389547PPFIA1chr1170118542+ENST00000355303ANO1chr1170007266+3369462481844598
ENST00000389547PPFIA1chr1170118542+ENST00000398543ANO1chr1170007266+3368462481844598
ENST00000389547PPFIA1chr1170118542+ENST00000538023ANO1chr1170007266+3368462481844598
ENST00000389547PPFIA1chr1170118542+ENST00000316296ANO1chr1170007266+107146248986312
ENST00000389547PPFIA1chr1170118542+ENST00000530676ANO1chr1170007266+2122462481844598
ENST00000389547PPFIA1chr1170118542+ENST00000531349ANO1chr1170007266+3093462481844598
ENST00000253925PPFIA1chr1170118542+ENST00000355303ANO1chr1169962564+4109479652584839
ENST00000253925PPFIA1chr1170118542+ENST00000398543ANO1chr1169962564+4018479652494809
ENST00000253925PPFIA1chr1170118542+ENST00000538023ANO1chr1169962564+4108479652584839
ENST00000253925PPFIA1chr1170118542+ENST00000316296ANO1chr1169962564+1721479651636523
ENST00000253925PPFIA1chr1170118542+ENST00000530676ANO1chr1169962564+2772479652494809
ENST00000253925PPFIA1chr1170118542+ENST00000531349ANO1chr1169962564+3755479652506813
ENST00000389547PPFIA1chr1170118542+ENST00000355303ANO1chr1169962564+4092462482567839
ENST00000389547PPFIA1chr1170118542+ENST00000398543ANO1chr1169962564+4001462482477809
ENST00000389547PPFIA1chr1170118542+ENST00000538023ANO1chr1169962564+4091462482567839
ENST00000389547PPFIA1chr1170118542+ENST00000316296ANO1chr1169962564+1704462481619523
ENST00000389547PPFIA1chr1170118542+ENST00000530676ANO1chr1169962564+2755462482477809
ENST00000389547PPFIA1chr1170118542+ENST00000531349ANO1chr1169962564+3738462482489813
ENST00000253925PPFIA1chr1170118542+ENST00000355303ANO1chr1169933858+48564796533311088
ENST00000389547PPFIA1chr1170118542+ENST00000355303ANO1chr1169933858+48394624833141088
ENST00000253925PPFIA1chr1170118542-ENST00000355303ANO1chr1170007267+3386479651861598
ENST00000253925PPFIA1chr1170118542-ENST00000398543ANO1chr1170007267+3385479651861598
ENST00000253925PPFIA1chr1170118542-ENST00000538023ANO1chr1170007267+3385479651861598
ENST00000253925PPFIA1chr1170118542-ENST00000316296ANO1chr1170007267+1088479651003312
ENST00000253925PPFIA1chr1170118542-ENST00000530676ANO1chr1170007267+2139479651861598
ENST00000253925PPFIA1chr1170118542-ENST00000531349ANO1chr1170007267+3110479651861598
ENST00000389547PPFIA1chr1170118542-ENST00000355303ANO1chr1170007267+3369462481844598
ENST00000389547PPFIA1chr1170118542-ENST00000398543ANO1chr1170007267+3368462481844598
ENST00000389547PPFIA1chr1170118542-ENST00000538023ANO1chr1170007267+3368462481844598
ENST00000389547PPFIA1chr1170118542-ENST00000316296ANO1chr1170007267+107146248986312
ENST00000389547PPFIA1chr1170118542-ENST00000530676ANO1chr1170007267+2122462481844598
ENST00000389547PPFIA1chr1170118542-ENST00000531349ANO1chr1170007267+3093462481844598
ENST00000253925PPFIA1chr1170118541+ENST00000355303ANO1chr1169962563+4109479652584839
ENST00000253925PPFIA1chr1170118541+ENST00000398543ANO1chr1169962563+4018479652494809
ENST00000253925PPFIA1chr1170118541+ENST00000538023ANO1chr1169962563+4108479652584839
ENST00000253925PPFIA1chr1170118541+ENST00000316296ANO1chr1169962563+1721479651636523
ENST00000253925PPFIA1chr1170118541+ENST00000530676ANO1chr1169962563+2772479652494809
ENST00000253925PPFIA1chr1170118541+ENST00000531349ANO1chr1169962563+3755479652506813
ENST00000389547PPFIA1chr1170118541+ENST00000355303ANO1chr1169962563+4092462482567839
ENST00000389547PPFIA1chr1170118541+ENST00000398543ANO1chr1169962563+4001462482477809
ENST00000389547PPFIA1chr1170118541+ENST00000538023ANO1chr1169962563+4091462482567839
ENST00000389547PPFIA1chr1170118541+ENST00000316296ANO1chr1169962563+1704462481619523
ENST00000389547PPFIA1chr1170118541+ENST00000530676ANO1chr1169962563+2755462482477809
ENST00000389547PPFIA1chr1170118541+ENST00000531349ANO1chr1169962563+3738462482489813

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000253925ENST00000355303PPFIA1chr1170118542+ANO1chr1169962563+0.0023431390.9976568
ENST00000253925ENST00000398543PPFIA1chr1170118542+ANO1chr1169962563+0.0017308190.9982692
ENST00000253925ENST00000538023PPFIA1chr1170118542+ANO1chr1169962563+0.0023393630.99766064
ENST00000253925ENST00000316296PPFIA1chr1170118542+ANO1chr1169962563+0.0045660250.995434
ENST00000253925ENST00000530676PPFIA1chr1170118542+ANO1chr1169962563+0.0060554120.9939446
ENST00000253925ENST00000531349PPFIA1chr1170118542+ANO1chr1169962563+0.0041385530.9958615
ENST00000389547ENST00000355303PPFIA1chr1170118542+ANO1chr1169962563+0.002328270.99767166
ENST00000389547ENST00000398543PPFIA1chr1170118542+ANO1chr1169962563+0.0017208780.9982791
ENST00000389547ENST00000538023PPFIA1chr1170118542+ANO1chr1169962563+0.0023243430.9976757
ENST00000389547ENST00000316296PPFIA1chr1170118542+ANO1chr1169962563+0.0044596680.9955403
ENST00000389547ENST00000530676PPFIA1chr1170118542+ANO1chr1169962563+0.0060192210.99398077
ENST00000389547ENST00000531349PPFIA1chr1170118542+ANO1chr1169962563+0.0041184910.99588156
ENST00000253925ENST00000355303PPFIA1chr1170118542+ANO1chr1170007266+0.0017303670.99826956
ENST00000253925ENST00000398543PPFIA1chr1170118542+ANO1chr1170007266+0.0017262180.99827373
ENST00000253925ENST00000538023PPFIA1chr1170118542+ANO1chr1170007266+0.0017262180.99827373
ENST00000253925ENST00000316296PPFIA1chr1170118542+ANO1chr1170007266+0.0037853960.99621457
ENST00000253925ENST00000530676PPFIA1chr1170118542+ANO1chr1170007266+0.0046415910.9953584
ENST00000253925ENST00000531349PPFIA1chr1170118542+ANO1chr1170007266+0.0029108650.9970892
ENST00000389547ENST00000355303PPFIA1chr1170118542+ANO1chr1170007266+0.0017107410.9982893
ENST00000389547ENST00000398543PPFIA1chr1170118542+ANO1chr1170007266+0.0017053190.99829465
ENST00000389547ENST00000538023PPFIA1chr1170118542+ANO1chr1170007266+0.0017053190.99829465
ENST00000389547ENST00000316296PPFIA1chr1170118542+ANO1chr1170007266+0.003491130.9965089
ENST00000389547ENST00000530676PPFIA1chr1170118542+ANO1chr1170007266+0.0045974410.9954026
ENST00000389547ENST00000531349PPFIA1chr1170118542+ANO1chr1170007266+0.0028882240.9971118
ENST00000253925ENST00000355303PPFIA1chr1170118542+ANO1chr1169962564+0.0023431390.9976568
ENST00000253925ENST00000398543PPFIA1chr1170118542+ANO1chr1169962564+0.0017308190.9982692
ENST00000253925ENST00000538023PPFIA1chr1170118542+ANO1chr1169962564+0.0023393630.99766064
ENST00000253925ENST00000316296PPFIA1chr1170118542+ANO1chr1169962564+0.0045660250.995434
ENST00000253925ENST00000530676PPFIA1chr1170118542+ANO1chr1169962564+0.0060554120.9939446
ENST00000253925ENST00000531349PPFIA1chr1170118542+ANO1chr1169962564+0.0041385530.9958615
ENST00000389547ENST00000355303PPFIA1chr1170118542+ANO1chr1169962564+0.002328270.99767166
ENST00000389547ENST00000398543PPFIA1chr1170118542+ANO1chr1169962564+0.0017208780.9982791
ENST00000389547ENST00000538023PPFIA1chr1170118542+ANO1chr1169962564+0.0023243430.9976757
ENST00000389547ENST00000316296PPFIA1chr1170118542+ANO1chr1169962564+0.0044596680.9955403
ENST00000389547ENST00000530676PPFIA1chr1170118542+ANO1chr1169962564+0.0060192210.99398077
ENST00000389547ENST00000531349PPFIA1chr1170118542+ANO1chr1169962564+0.0041184910.99588156
ENST00000253925ENST00000355303PPFIA1chr1170118542+ANO1chr1169933858+0.0017132330.9982868
ENST00000389547ENST00000355303PPFIA1chr1170118542+ANO1chr1169933858+0.0016679380.9983321
ENST00000253925ENST00000355303PPFIA1chr1170118542-ANO1chr1170007267+0.0017303670.99826956
ENST00000253925ENST00000398543PPFIA1chr1170118542-ANO1chr1170007267+0.0017262180.99827373
ENST00000253925ENST00000538023PPFIA1chr1170118542-ANO1chr1170007267+0.0017262180.99827373
ENST00000253925ENST00000316296PPFIA1chr1170118542-ANO1chr1170007267+0.0037853960.99621457
ENST00000253925ENST00000530676PPFIA1chr1170118542-ANO1chr1170007267+0.0046415910.9953584
ENST00000253925ENST00000531349PPFIA1chr1170118542-ANO1chr1170007267+0.0029108650.9970892
ENST00000389547ENST00000355303PPFIA1chr1170118542-ANO1chr1170007267+0.0017107410.9982893
ENST00000389547ENST00000398543PPFIA1chr1170118542-ANO1chr1170007267+0.0017053190.99829465
ENST00000389547ENST00000538023PPFIA1chr1170118542-ANO1chr1170007267+0.0017053190.99829465
ENST00000389547ENST00000316296PPFIA1chr1170118542-ANO1chr1170007267+0.003491130.9965089
ENST00000389547ENST00000530676PPFIA1chr1170118542-ANO1chr1170007267+0.0045974410.9954026
ENST00000389547ENST00000531349PPFIA1chr1170118542-ANO1chr1170007267+0.0028882240.9971118
ENST00000253925ENST00000355303PPFIA1chr1170118541+ANO1chr1169962563+0.0023431390.9976568
ENST00000253925ENST00000398543PPFIA1chr1170118541+ANO1chr1169962563+0.0017308190.9982692
ENST00000253925ENST00000538023PPFIA1chr1170118541+ANO1chr1169962563+0.0023393630.99766064
ENST00000253925ENST00000316296PPFIA1chr1170118541+ANO1chr1169962563+0.0045660250.995434
ENST00000253925ENST00000530676PPFIA1chr1170118541+ANO1chr1169962563+0.0060554120.9939446
ENST00000253925ENST00000531349PPFIA1chr1170118541+ANO1chr1169962563+0.0041385530.9958615
ENST00000389547ENST00000355303PPFIA1chr1170118541+ANO1chr1169962563+0.002328270.99767166
ENST00000389547ENST00000398543PPFIA1chr1170118541+ANO1chr1169962563+0.0017208780.9982791
ENST00000389547ENST00000538023PPFIA1chr1170118541+ANO1chr1169962563+0.0023243430.9976757
ENST00000389547ENST00000316296PPFIA1chr1170118541+ANO1chr1169962563+0.0044596680.9955403
ENST00000389547ENST00000530676PPFIA1chr1170118541+ANO1chr1169962563+0.0060192210.99398077
ENST00000389547ENST00000531349PPFIA1chr1170118541+ANO1chr1169962563+0.0041184910.99588156

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>67382_67382_1_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_2_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_3_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_4_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_5_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_6_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000253925_ANO1_chr11_69962563_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_7_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_8_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_9_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_10_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_11_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_12_PPFIA1-ANO1_PPFIA1_chr11_70118541_ENST00000389547_ANO1_chr11_69962563_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_13_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69933858_ENST00000355303_length(amino acids)=1088AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRT
LVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCRE
AEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT
CTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIV
GIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRW
DLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIA
VTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNS
YTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVK
RKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV
IINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA
ARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPS

--------------------------------------------------------------

>67382_67382_14_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_15_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_16_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_17_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_18_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_19_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962563_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_20_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_21_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_22_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_23_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_24_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_25_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_69962564_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_26_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000316296_length(amino acids)=312AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEEVTEILFIS

--------------------------------------------------------------

>67382_67382_27_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000355303_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_28_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000398543_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_29_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000530676_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_30_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000531349_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_31_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007266_ENST00000538023_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_32_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000316296_length(amino acids)=312AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEEVTEILFIS

--------------------------------------------------------------

>67382_67382_33_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000355303_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_34_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000398543_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_35_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000530676_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_36_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000531349_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_37_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000253925_ANO1_chr11_70007267_ENST00000538023_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_38_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69933858_ENST00000355303_length(amino acids)=1088AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRT
LVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCRE
AEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTT
CTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIV
GIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRW
DLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIA
VTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNS
YTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVK
RKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAV
IINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLA
ARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPS

--------------------------------------------------------------

>67382_67382_39_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_40_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_41_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_42_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_43_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_44_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962563_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_45_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000316296_length(amino acids)=523AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF

--------------------------------------------------------------

>67382_67382_46_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000355303_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_47_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000398543_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_48_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000530676_length(amino acids)=809AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGV
IIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAF
FKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDY
NLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISF
TSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVF

--------------------------------------------------------------

>67382_67382_49_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000531349_length(amino acids)=813AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAI
VLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIF
YVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRY
EVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAF
VISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAF
VIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHG

--------------------------------------------------------------

>67382_67382_50_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_69962564_ENST00000538023_length(amino acids)=839AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEKALLDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE

--------------------------------------------------------------

>67382_67382_51_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000316296_length(amino acids)=312AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEEVTEILFIS

--------------------------------------------------------------

>67382_67382_52_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000355303_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_53_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000398543_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_54_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000530676_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_55_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000531349_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_56_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007266_ENST00000538023_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_57_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000316296_length(amino acids)=312AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEEVTEILFIS

--------------------------------------------------------------

>67382_67382_58_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000355303_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_59_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000398543_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_60_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000530676_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_61_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000531349_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

>67382_67382_62_PPFIA1-ANO1_PPFIA1_chr11_70118542_ENST00000389547_ANO1_chr11_70007267_ENST00000538023_length(amino acids)=598AA_BP=3
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATA
VIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLM
ELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPL
APLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSF
NVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKV

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:70118542/chr11:69962564)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ANO1

Q9NW15

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1. {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+22617_2588.01186.0Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-22817_2588.01597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-22617_2588.01186.0Compositional biasNote=Poly-Gly
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617355_406257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617428_519257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617541_568257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617590_607257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617629_657257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617679_725257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617768_784257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617806_892257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617914_986257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626355_406285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626428_519285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626541_568285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626590_607285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626629_657285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626679_725285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626768_784285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626806_892285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626914_986285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624355_406169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624428_519169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624541_568169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624590_607169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624629_657169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624679_725169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624768_784169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624806_892169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624914_986169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625355_406169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625428_519169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625541_568169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625590_607169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625629_657169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625679_725169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625768_784169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625806_892169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625914_986169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017355_4068.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017428_5198.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017541_5688.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017590_6078.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017629_6578.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017679_7258.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017768_7848.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017806_8928.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017914_9868.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026355_40636.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026428_51936.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026541_56836.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026590_60736.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026629_65736.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026679_72536.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026768_78436.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026806_89236.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026914_98636.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST000003985430241_3330841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024355_4060841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024428_5190841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024541_5680841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024590_6070841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024629_6570841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024679_7250841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024768_7840841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024806_8920841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024914_9860841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST000005306760251_3330819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025355_4060819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025428_5190819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025541_5680819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025590_6070819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025629_6570819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025679_7250819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025768_7840819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025806_8920819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025914_9860819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617355_406257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617428_519257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617541_568257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617590_607257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617629_657257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617679_725257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617768_784257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617806_892257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617914_986257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626355_406285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626428_519285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626541_568285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626590_607285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626629_657285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626679_725285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626768_784285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626806_892285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626914_986285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624355_406169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624428_519169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624541_568169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624590_607169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624629_657169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624679_725169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624768_784169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624806_892169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624914_986169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625355_406169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625428_519169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625541_568169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625590_607169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625629_657169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625679_725169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625768_784169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625806_892169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625914_986169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617355_406257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617428_519257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617541_568257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617590_607257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617629_657257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617679_725257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617768_784257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617806_892257.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617914_986257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626355_406285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626428_519285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626541_568285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626590_607285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626629_657285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626679_725285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626768_784285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626806_892285.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626914_986285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624355_406169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624428_519169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624541_568169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624590_607169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624629_657169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624679_725169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624768_784169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624806_892169.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624914_986169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625355_406169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625428_519169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625541_568169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625590_607169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625629_657169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625679_725169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625768_784169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625806_892169.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625914_986169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317541_568468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317590_607468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317629_657468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317679_725468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317768_784468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317806_892468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317914_986468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526541_568526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526590_607526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526629_657526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526679_725526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526768_784526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526806_892526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526914_986526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324428_519380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324541_568380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324590_607380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324629_657380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324679_725380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324768_784380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324806_892380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324914_986380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325428_519380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325541_568380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325590_607380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325629_657380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325679_725380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325768_784380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325806_892380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325914_986380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317541_568468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317590_607468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317629_657468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317679_725468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317768_784468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317806_892468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317914_986468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526541_568526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526590_607526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526629_657526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526679_725526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526768_784526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526806_892526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526914_986526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324428_519380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324541_568380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324590_607380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324629_657380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324679_725380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324768_784380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324806_892380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324914_986380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325428_519380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325541_568380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325590_607380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325629_657380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325679_725380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325768_784380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325806_892380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325914_986380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617334_354257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617407_427257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617520_540257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617569_589257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617608_628257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617658_678257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617726_746257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617747_767257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617785_805257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000316296617893_913257.0643.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626334_354285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626407_427285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626520_540285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626569_589285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626608_628285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626658_678285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626726_746285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626747_767285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626785_805285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000355303626893_913285.0987.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624334_354169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624407_427169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624520_540169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624569_589169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624608_628169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624658_678169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624726_746169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624747_767169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624785_805169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000398543624893_913169.0841.0TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625334_354169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625407_427169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625520_540169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625569_589169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625608_628169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625658_678169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625726_746169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625747_767169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625785_805169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118541chr11:69962563ENST00000530676625893_913169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017334_3548.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017407_4278.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017520_5408.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017569_5898.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017608_6288.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017658_6788.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017726_7468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017747_7678.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017785_8058.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000316296017893_9138.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026334_35436.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026407_42736.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026520_54036.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026569_58936.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026608_62836.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026658_67836.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026726_74636.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026747_76736.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026785_80536.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000355303026893_91336.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024334_3540841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024407_4270841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024520_5400841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024569_5890841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024608_6280841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024658_6780841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024726_7460841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024747_7670841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024785_8050841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000398543024893_9130841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025334_3540819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025407_4270819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025520_5400819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025569_5890819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025608_6280819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025658_6780819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025726_7460819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025747_7670819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025785_8050819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69933858ENST00000530676025893_9130819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617334_354257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617407_427257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617520_540257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617569_589257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617608_628257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617658_678257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617726_746257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617747_767257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617785_805257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000316296617893_913257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626334_354285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626407_427285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626520_540285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626569_589285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626608_628285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626658_678285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626726_746285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626747_767285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626785_805285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000355303626893_913285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624334_354169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624407_427169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624520_540169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624569_589169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624608_628169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624658_678169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624726_746169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624747_767169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624785_805169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000398543624893_913169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625334_354169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625407_427169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625520_540169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625569_589169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625608_628169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625658_678169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625726_746169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625747_767169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625785_805169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962563ENST00000530676625893_913169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617334_354257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617407_427257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617520_540257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617569_589257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617608_628257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617658_678257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617726_746257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617747_767257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617785_805257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000316296617893_913257.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626334_354285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626407_427285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626520_540285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626569_589285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626608_628285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626658_678285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626726_746285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626747_767285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626785_805285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000355303626893_913285.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624334_354169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624407_427169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624520_540169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624569_589169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624608_628169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624658_678169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624726_746169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624747_767169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624785_805169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000398543624893_913169.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625334_354169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625407_427169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625520_540169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625569_589169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625608_628169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625658_678169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625726_746169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625747_767169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625785_805169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:69962564ENST00000530676625893_913169.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317520_540468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317569_589468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317608_628468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317658_678468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317726_746468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317747_767468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317785_805468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317893_913468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526569_589526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526608_628526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526658_678526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526726_746526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526747_767526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526785_805526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526893_913526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324407_427380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324520_540380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324569_589380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324608_628380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324658_678380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324726_746380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324747_767380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324785_805380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324893_913380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325407_427380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325520_540380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325569_589380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325608_628380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325658_678380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325726_746380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325747_767380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325785_805380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325893_913380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317520_540468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317569_589468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317608_628468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317658_678468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317726_746468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317747_767468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317785_805468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317893_913468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526569_589526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526608_628526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526658_678526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526726_746526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526747_767526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526785_805526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526893_913526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324407_427380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324520_540380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324569_589380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324608_628380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324658_678380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324726_746380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324747_767380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324785_805380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324893_913380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325407_427380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325520_540380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325569_589380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325608_628380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325658_678380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325726_746380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325747_767380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325785_805380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325893_913380.0819.3333333333334TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-2281021_105088.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228176_21488.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228249_52188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-22834_14188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228623_66988.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228847_87188.01597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-2261021_105088.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226176_21488.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226249_52188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-22634_14188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226623_66988.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226847_87188.01186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118541chr11:69962563ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118541chr11:69962563ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69933858ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69933858ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69962563ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69962563ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69962564ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:69962564ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:70007266ENST00000253925+228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:70007266ENST00000389547+226963_102788.01186.0DomainSAM 2
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-2281051_112088.01597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228878_94488.01597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:70007267ENST00000253925-228963_102788.01597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-2261051_112088.01186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226878_94488.01186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:70007267ENST00000389547-226963_102788.01186.0DomainSAM 2
TgeneANO1chr11:70118541chr11:69962563ENST000003162966171_333257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST000003553036261_333285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST000003985436241_333169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118541chr11:69962563ENST000005306766251_333169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST000003162960171_3338.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69933858ENST000003553030261_33336.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST000003162966171_333257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST000003553036261_333285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST000003985436241_333169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962563ENST000005306766251_333169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST000003162966171_333257.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST000003553036261_333285.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST000003985436241_333169.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:69962564ENST000005306766251_333169.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST0000031629613171_333468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317355_406468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317428_519468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST0000035530315261_333526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526355_406526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526428_519526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST0000039854313241_333380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324355_406380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST0000053067613251_333380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325355_406380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST0000031629613171_333468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317355_406468.0643.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317428_519468.0643.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST0000035530315261_333526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526355_406526.0987.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526428_519526.0987.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST0000039854313241_333380.0841.0Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324355_406380.0841.0Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007267ENST0000053067613251_333380.0819.3333333333334Topological domainCytoplasmic
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325355_406380.0819.3333333333334Topological domainExtracellular
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317334_354468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003162961317407_427468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526334_354526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526407_427526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003553031526520_540526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000003985431324334_354380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007266ENST000005306761325334_354380.0819.3333333333334TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317334_354468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003162961317407_427468.0643.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526334_354526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526407_427526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003553031526520_540526.0987.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000003985431324334_354380.0841.0TransmembraneHelical
TgeneANO1chr11:70118542chr11:70007267ENST000005306761325334_354380.0819.3333333333334TransmembraneHelical


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>1624_PPFIA1_70118542_ANO1_69962564_ranked_0.pdbPPFIA17011854170118542ENST00000531349ANO1chr1169962564+
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEK
IGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMA
LWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKL
TWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPK
TEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMK
KLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVA
VRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDY
REPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDE
839


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
PPFIA1_pLDDT.png
all structure
all structure
ANO1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PPFIA1
ANO1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to PPFIA1-ANO1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PPFIA1-ANO1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource