UTHEALTH HOME    ABOUT SBMI    A-Z    WEBMAIL    INSIDE THE UNIVERSITY
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Terms of Use
Center for Computational Systems Medicine level1
leaf

Fusion Gene Summary

leaf

Fusion Gene Sample Information

leaf

Fusion ORF Analysis

leaf

Fusion Amino Acid Sequences

leaf

Fusion Protein Functional Features

leaf

Fusion Protein-Protein Interaction

leaf

Related drugs with this fusion protein

leaf

Related disease with this fusion protein

Fusion Protein:PPP2R4-MUSK

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PPP2R4-MUSK
FusionPDB ID: 68053
FusionGDB2.0 ID: 68053
HgeneTgene
Gene symbol

PPP2R4

MUSK

Gene ID

5524

4593

Gene nameprotein phosphatase 2 phosphatase activatormuscle associated receptor tyrosine kinase
SynonymsPP2A|PPP2R4|PR53CMS9|FADS|FADS1
Cytomap

9q34.11

9q31.3

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 2A activatorPP2A phosphatase activatorPP2A subunit B' isoform PR53phosphotyrosyl phosphatase activatorprotein phosphatase 2 regulatory subunit 4protein phosphatase 2A activator, regulatory subunit 4protein phosphmuscle, skeletal receptor tyrosine-protein kinasemuscle, skeletal, receptor tyrosine kinasemuscle-specific kinase receptormuscle-specific tyrosine-protein kinase receptor
Modification date2020032920200313
UniProtAcc.

O15146

Ensembl transtripts involved in fusion geneENST idsENST00000337738, ENST00000347048, 
ENST00000348141, ENST00000355007, 
ENST00000357197, ENST00000358994, 
ENST00000393370, ENST00000414510, 
ENST00000419582, ENST00000423100, 
ENST00000432124, ENST00000432651, 
ENST00000434095, ENST00000435132, 
ENST00000435305, ENST00000436883, 
ENST00000452489, ENST00000524946, 
ENST00000374438, ENST00000374439, 
ENST00000374440, ENST00000189978, 
ENST00000374448, ENST00000416899, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score10 X 9 X 8=7205 X 6 X 2=60
# samples 127
** MAII scorelog2(12/720*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/60*10)=0.222392421336448
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PPP2R4 [Title/Abstract] AND MUSK [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PPP2R4(131904831)-MUSK(113509921), # samples:1
Anticipated loss of major functional domain due to fusion event.PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PPP2R4-MUSK seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePPP2R4

GO:0032515

negative regulation of phosphoprotein phosphatase activity

16916641

HgenePPP2R4

GO:0032516

positive regulation of phosphoprotein phosphatase activity

16916641

HgenePPP2R4

GO:0035307

positive regulation of protein dephosphorylation

16916641

HgenePPP2R4

GO:0035308

negative regulation of protein dephosphorylation

16916641

HgenePPP2R4

GO:0043065

positive regulation of apoptotic process

17333320

HgenePPP2R4

GO:0043666

regulation of phosphoprotein phosphatase activity

16916641

TgeneMUSK

GO:0007528

neuromuscular junction development

25537362


check buttonFusion gene breakpoints across PPP2R4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MUSK (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


Top

Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A48K-01APPP2R4chr9

131904831

+MUSKchr9

113509921

+


Top

Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000358994PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2973110682962984
ENST00000358994PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2973110682962984
ENST00000358994PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+3530110682938976
ENST00000393370PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+304411771693033954
ENST00000393370PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+304411771693033954
ENST00000393370PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+360111771693009946
ENST00000337738PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+313312661533122989
ENST00000337738PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+313312661533122989
ENST00000337738PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+369012661533098981
ENST00000348141PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+304411771513033960
ENST00000348141PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+304411771513033960
ENST00000348141PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+360111771513009952
ENST00000452489PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+30791212993068989
ENST00000452489PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+30791212993068989
ENST00000452489PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+36361212993044981
ENST00000357197PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2866999782855925
ENST00000357197PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2866999782855925
ENST00000357197PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+3423999782831917
ENST00000347048PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2296429782285735
ENST00000347048PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2296429782285735
ENST00000347048PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+2853429782261727
ENST00000355007PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2822955732811912
ENST00000355007PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2822955732811912
ENST00000355007PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+3379955732787904
ENST00000423100PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+22433762652232655
ENST00000423100PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+22433762652232655
ENST00000423100PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+28003762652208647
ENST00000524946PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2963109610362952638
ENST00000524946PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2963109610362952638
ENST00000524946PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+3520109610362928630
ENST00000436883PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+211925292108699
ENST00000436883PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+211925292108699
ENST00000436883PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+267625292084691
ENST00000414510PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+211925292108699
ENST00000414510PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+211925292108699
ENST00000414510PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+267625292084691
ENST00000432124PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2027160522016654
ENST00000432124PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2027160522016654
ENST00000432124PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+2584160521992646
ENST00000419582PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+22483812732237654
ENST00000419582PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+22483812732237654
ENST00000419582PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+28053812732213646
ENST00000432651PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+2104237722093673
ENST00000432651PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+2104237722093673
ENST00000432651PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+2661237722069665
ENST00000435132PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+20992321062088660
ENST00000435132PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+20992321062088660
ENST00000435132PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+26562321062064652
ENST00000434095PPP2R4chr9131904831+ENST00000189978MUSKchr9113509921+21282611472117656
ENST00000434095PPP2R4chr9131904831+ENST00000374448MUSKchr9113509921+21282611472117656
ENST00000434095PPP2R4chr9131904831+ENST00000416899MUSKchr9113509921+26852611472093648

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358994ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0017784640.9982216
ENST00000358994ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0017772410.99822277
ENST00000358994ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0008862860.99911374
ENST00000393370ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0022149390.997785
ENST00000393370ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0021970640.9978029
ENST00000393370ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0011857650.9988142
ENST00000337738ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0009545430.99904543
ENST00000337738ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0009473230.9990527
ENST00000337738ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0005694040.9994306
ENST00000348141ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0017192060.99828076
ENST00000348141ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0017073940.9982926
ENST00000348141ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0008367220.99916327
ENST00000452489ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0010259030.9989741
ENST00000452489ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0010185740.9989814
ENST00000452489ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0005900390.9994099
ENST00000357197ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0025882210.9974118
ENST00000357197ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0025603280.9974396
ENST00000357197ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0011305360.9988695
ENST00000347048ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0115382930.98846173
ENST00000347048ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0115026660.9884974
ENST00000347048ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0040829530.995917
ENST00000355007ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0021672160.99783283
ENST00000355007ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0021472440.9978528
ENST00000355007ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.00099090.999009
ENST00000423100ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0140377320.9859622
ENST00000423100ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0131585560.98684144
ENST00000423100ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.005498020.99450195
ENST00000524946ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0085362430.9914637
ENST00000524946ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0091172810.9908827
ENST00000524946ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0034457290.99655426
ENST00000436883ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0120535240.98794645
ENST00000436883ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0109210080.98907894
ENST00000436883ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0044332890.99556667
ENST00000414510ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0120535240.98794645
ENST00000414510ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0109210080.98907894
ENST00000414510ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0044332890.99556667
ENST00000432124ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0127425670.9872574
ENST00000432124ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0115202630.9884798
ENST00000432124ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0045820940.99541795
ENST00000419582ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0139342840.98606575
ENST00000419582ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0131223440.9868776
ENST00000419582ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0054475560.99455243
ENST00000432651ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0130824410.98691756
ENST00000432651ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0121064860.9878935
ENST00000432651ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0046351160.9953649
ENST00000435132ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0136285050.98637146
ENST00000435132ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0126531970.9873468
ENST00000435132ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0047367090.99526334
ENST00000434095ENST00000189978PPP2R4chr9131904831+MUSKchr9113509921+0.0129135360.9870864
ENST00000434095ENST00000374448PPP2R4chr9131904831+MUSKchr9113509921+0.0119685450.9880314
ENST00000434095ENST00000416899PPP2R4chr9131904831+MUSKchr9113509921+0.0045292120.99547076

Top

Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>68053_68053_1_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000337738_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=989AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLL
TITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVS
SPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT

--------------------------------------------------------------

>68053_68053_2_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000337738_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=989AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLL
TITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVS
SPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT

--------------------------------------------------------------

>68053_68053_3_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000337738_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=981AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCC
RRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV
KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS
CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAY

--------------------------------------------------------------

>68053_68053_4_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000347048_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=735AA_BP=117
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQMKTGPFAEH
SNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNK
GYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKEL
FCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSM
TVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEG
AFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHT
VCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAI
PIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHR

--------------------------------------------------------------

>68053_68053_5_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000347048_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=735AA_BP=117
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQMKTGPFAEH
SNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNK
GYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKEL
FCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSM
TVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEG
AFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHT
VCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAI
PIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHR

--------------------------------------------------------------

>68053_68053_6_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000347048_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=727AA_BP=117
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQMKTGPFAEH
SNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNK
GYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKEL
FCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMS
SFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQA
RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD
LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPE
SIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCER

--------------------------------------------------------------

>68053_68053_7_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000348141_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=960AA_BP=342
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQVPFGTVAYA
DYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVA
VYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ
LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSR
LQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNEL
KVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACAR
LPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTL
PSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAAL
MAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSER
KFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHE

--------------------------------------------------------------

>68053_68053_8_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000348141_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=960AA_BP=342
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQVPFGTVAYA
DYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVA
VYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ
LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSR
LQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNEL
KVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACAR
LPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTL
PSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAAL
MAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSER
KFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHE

--------------------------------------------------------------

>68053_68053_9_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000348141_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=952AA_BP=342
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQVPFGTVAYA
DYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVA
VYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQ
LIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSR
LQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNEL
KVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACAR
LPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDR
LHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPN
IVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLA
TRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRD

--------------------------------------------------------------

>68053_68053_10_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000355007_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=912AA_BP=294
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKV
FNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQ
LWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYC
AQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCA
KEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVI
ISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFG
RVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCS
LSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIR
WMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILE

--------------------------------------------------------------

>68053_68053_11_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000355007_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=912AA_BP=294
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKV
FNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQ
LWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYC
AQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCA
KEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVI
ISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFG
RVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCS
LSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIR
WMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILE

--------------------------------------------------------------

>68053_68053_12_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000355007_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=904AA_BP=294
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKV
FNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQ
LWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYC
AQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCA
KEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFA
IFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAP
GLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSM
RAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIF
YNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCERAEG

--------------------------------------------------------------

>68053_68053_13_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000357197_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=925AA_BP=307
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAIEKLVALL
NTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGV
LRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFIT
EMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
AFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSS
SFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNN
IEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLN
EFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSAD
YYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPA

--------------------------------------------------------------

>68053_68053_14_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000357197_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=925AA_BP=307
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAIEKLVALL
NTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGV
LRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFIT
EMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
EWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSS
SFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNN
IEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLN
EFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSAD
YYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPA

--------------------------------------------------------------

>68053_68053_15_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000357197_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=917AA_BP=307
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAIEKLVALL
NTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGV
LRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFIT
EMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
AFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTY
SMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIG
EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSP
HTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANEND
AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSI

--------------------------------------------------------------

>68053_68053_16_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000358994_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=984AA_BP=366
MWRRKEEVTVQLSLPCPHMSSKLLEPAGAHLSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQN
FIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKL
DEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRME
PAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLI
RMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALV
FLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSE
MHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTL
YCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM
VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPP
PLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDV

--------------------------------------------------------------

>68053_68053_17_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000358994_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=984AA_BP=366
MWRRKEEVTVQLSLPCPHMSSKLLEPAGAHLSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQN
FIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKL
DEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRME
PAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLI
RMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALV
FLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSE
MHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTL
YCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTM
VAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPP
PLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDV

--------------------------------------------------------------

>68053_68053_18_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000358994_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=976AA_BP=366
MWRRKEEVTVQLSLPCPHMSSKLLEPAGAHLSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQN
FIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKL
DEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRME
PAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLI
RMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALV
FLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSE
MHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQ
WKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKE
EASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQL
CIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLW

--------------------------------------------------------------

>68053_68053_19_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000393370_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=954AA_BP=336
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKES
VGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPY
LEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFIT
KPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPV
CRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDY
NKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLL
DRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDN
PNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD
LATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYV

--------------------------------------------------------------

>68053_68053_20_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000393370_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=954AA_BP=336
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKES
VGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPY
LEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFIT
KPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPV
CRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDY
NKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLL
DRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDN
PNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRD
LATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYV

--------------------------------------------------------------

>68053_68053_21_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000393370_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=946AA_BP=336
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKES
VGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPY
LEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFIT
KPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPV
CRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAF
PPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPM
YQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLG
VCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLV
GENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSC

--------------------------------------------------------------

>68053_68053_22_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000414510_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=699AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQ
ADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGL

--------------------------------------------------------------

>68053_68053_23_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000414510_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=699AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQ
ADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGL

--------------------------------------------------------------

>68053_68053_24_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000414510_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=691AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTT
LPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAA
LMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSE
RKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAH

--------------------------------------------------------------

>68053_68053_25_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000419582_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=654AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAA
FSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSS
FSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNI
EYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE
FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADY
YKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPAD

--------------------------------------------------------------

>68053_68053_26_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000419582_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=654AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAE
WSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSS
FSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNI
EYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE
FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADY
YKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPAD

--------------------------------------------------------------

>68053_68053_27_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000419582_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=646AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAA
FSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYS
MTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGE
GAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPH
TVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDA
IPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIH

--------------------------------------------------------------

>68053_68053_28_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000423100_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=655AA_BP=37
MMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
AFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSS
SFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNN
IEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLN
EFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSAD
YYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPA

--------------------------------------------------------------

>68053_68053_29_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000423100_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=655AA_BP=37
MMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
EWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSS
SFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNN
IEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLN
EFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSAD
YYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPA

--------------------------------------------------------------

>68053_68053_30_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000423100_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=647AA_BP=37
MMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIA
AFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPIC
REYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTY
SMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIG
EGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSP
HTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANEND
AIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSI

--------------------------------------------------------------

>68053_68053_31_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432124_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=654AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAA
FSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSS
FSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNI
EYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE
FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADY
YKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPAD

--------------------------------------------------------------

>68053_68053_32_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432124_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=654AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAE
WSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSS
FSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNI
EYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNE
FLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADY
YKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPAD

--------------------------------------------------------------

>68053_68053_33_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432124_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=646AA_BP=36
MKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAA
FSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICR
EYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYS
MTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGE
GAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPH
TVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDA
IPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIH

--------------------------------------------------------------

>68053_68053_34_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432651_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=673AA_BP=55
MERRSEAPGESVGTTPEAQMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATN
KHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCN
HIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPM
TSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQR
MPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA
VGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGEN
MVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPEN

--------------------------------------------------------------

>68053_68053_35_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432651_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=673AA_BP=55
MERRSEAPGESVGTTPEAQMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATN
KHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCN
HIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPM
TSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQR
MPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCA
VGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGEN
MVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPEN

--------------------------------------------------------------

>68053_68053_36_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000432651_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=665AA_BP=55
MERRSEAPGESVGTTPEAQMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATN
KHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCN
HIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVD
IPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPK
LLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLL
FEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADF
GLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNL

--------------------------------------------------------------

>68053_68053_37_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000434095_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=656AA_BP=38
MRMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISI
AAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPI
CREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSS
SSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRN
NIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL
NEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSA
DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLP

--------------------------------------------------------------

>68053_68053_38_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000434095_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=656AA_BP=38
MRMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISI
AEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPI
CREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSS
SSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRN
NIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDL
NEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSA
DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLP

--------------------------------------------------------------

>68053_68053_39_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000434095_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=648AA_BP=38
MRMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISI
AAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPI
CREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPT
YSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDI
GEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMS
PHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANEN
DAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTS

--------------------------------------------------------------

>68053_68053_40_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000435132_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=660AA_BP=42
MRLLDLMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAA
TISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPT
PIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLP
SSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLE
YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMA
YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRN
IYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCW

--------------------------------------------------------------

>68053_68053_41_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000435132_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=660AA_BP=42
MRLLDLMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAA
TISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPT
PIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLP
SSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLE
YPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMA
YGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRN
IYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCW

--------------------------------------------------------------

>68053_68053_42_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000435132_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=652AA_BP=42
MRLLDLMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAA
TISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPT
PIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFS
VSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEY
VRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFL
RSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYK
ANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRP

--------------------------------------------------------------

>68053_68053_43_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000436883_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=699AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQ
ADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGL

--------------------------------------------------------------

>68053_68053_44_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000436883_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=699AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQ
ADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGL

--------------------------------------------------------------

>68053_68053_45_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000436883_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=691AA_BP=81
MEGKELTGRRCAEPPHPRPSPQLLTEEPFTKGRFSGEWRGRNAASMKTGPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAEVSSGSIQES
VKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSM
HWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTT
LPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAA
LMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSE
RKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAH

--------------------------------------------------------------

>68053_68053_46_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000452489_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=989AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLL
TITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVS
SPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT

--------------------------------------------------------------

>68053_68053_47_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000452489_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=989AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLL
TITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVS
SPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT

--------------------------------------------------------------

>68053_68053_48_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000452489_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=981AA_BP=371
MSSGSSEPLVEPGRGRVGARVKGERGLQASGSAPGRSKMAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFI
LTLNEGVKGKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLDRWIDETPPVDQPSRFGNKAYRT
WYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGNSTRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQK
TYRMEPAGSQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKTGPFAEHSNQLWNISAVPSWSKV
NQGLIRMYKAEVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYRGEVCNAVLA
KDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCC
RRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAV
KMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS
CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAY

--------------------------------------------------------------

>68053_68053_49_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000524946_MUSK_chr9_113509921_ENST00000189978_length(amino acids)=638AA_BP=20
MASDTVLWAPSLDSWPAFSSVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYR
GEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWL
VMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIM
SSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQ
ARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHS
DLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPP
ESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCE

--------------------------------------------------------------

>68053_68053_50_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000524946_MUSK_chr9_113509921_ENST00000374448_length(amino acids)=638AA_BP=20
MASDTVLWAPSLDSWPAFSSVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAEWSKPQKDNKGYCAQYR
GEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWL
VMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIM
SSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQ
ARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHS
DLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPP
ESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCE

--------------------------------------------------------------

>68053_68053_51_PPP2R4-MUSK_PPP2R4_chr9_131904831_ENST00000524946_MUSK_chr9_113509921_ENST00000416899_length(amino acids)=630AA_BP=20
MASDTVLWAPSLDSWPAFSSVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAATISIAAFSKPQKDNKGYCAQYR
GEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWL
VMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLAFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVL
LTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLP
YEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQV
SSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRY
TTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV

--------------------------------------------------------------

Top

Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:131904831/chr9:113509921)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MUSK

O15146

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362). Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation (By similarity). {ECO:0000250, ECO:0000269|PubMed:25537362}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R4chr9:131904831chr9:113509921ENST00000337738+1011183_189333.0359.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000337738+1011240_242333.0359.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000355007+89183_189256.0282.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000355007+89240_242256.0282.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000357197+89183_189269.0295.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000357197+89240_242269.0295.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000358994+1011183_189298.0324.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000358994+1011240_242298.0324.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000393370+910183_189298.0324.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000393370+910240_242298.0324.0Nucleotide bindingNote=ATP
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515312_450251.0870.0DomainFZ
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515575_856251.0870.0DomainProtein kinase
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515581_589251.0870.0Nucleotide bindingATP
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515517_869251.0870.0Topological domainCytoplasmic
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515496_516251.0870.0TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R4chr9:131904831chr9:113509921ENST00000337738+1011342_343333.0359.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000355007+89342_343256.0282.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000357197+89342_343269.0295.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000358994+1011342_343298.0324.0Nucleotide bindingNote=ATP
HgenePPP2R4chr9:131904831chr9:113509921ENST00000393370+910342_343298.0324.0Nucleotide bindingNote=ATP
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515121_205251.0870.0DomainNote=Ig-like 2
TgeneMUSKchr9:131904831chr9:113509921ENST00000374448515212_302251.0870.0DomainNote=Ig-like 3
TgeneMUSKchr9:131904831chr9:113509921ENST0000037444851528_116251.0870.0DomainNote=Ig-like 1
TgeneMUSKchr9:131904831chr9:113509921ENST0000037444851524_495251.0870.0Topological domainExtracellular


Top

Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PPP2R4
MUSK


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs to PPP2R4-MUSK


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

Top

Related Diseases to PPP2R4-MUSK


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource