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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PTPRD-CDC37L1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PTPRD-CDC37L1
FusionPDB ID: 70342
FusionGDB2.0 ID: 70342
HgeneTgene
Gene symbol

PTPRD

CDC37L1

Gene ID

5789

55664

Gene nameprotein tyrosine phosphatase receptor type Dcell division cycle 37 like 1
SynonymsHPTP|HPTPD|HPTPDELTA|PTPD|R-PTP-delta|RPTPDELTACDC37B|HARC
Cytomap

9p24.1-p23

9p24.1

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase deltaprotein tyrosine phosphatase, receptor type, delta polypeptiderceptor-type tyrosine-protein phosphatase deltahsp90 co-chaperone Cdc37-like 1CDC37 cell division cycle 37 homolog-like 1Hsp90-associating relative of Cdc37cell division cycle 37 homolog-like 1
Modification date2020032020200313
UniProtAcc.

Q7L3B6

Ensembl transtripts involved in fusion geneENST idsENST00000355233, ENST00000356435, 
ENST00000358503, ENST00000360074, 
ENST00000381196, ENST00000397606, 
ENST00000397611, ENST00000397617, 
ENST00000486161, ENST00000537002, 
ENST00000540109, ENST00000463477, 
ENST00000471274, 		ENST00000479095, 
ENST00000381854, ENST00000381858, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score26 X 25 X 7=45503 X 3 X 3=27
# samples 283
** MAII scorelog2(28/4550*10)=-4.02236781302845
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PTPRD [Title/Abstract] AND CDC37L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PTPRD(8404537)-CDC37L1(4697096), # samples:1
Anticipated loss of major functional domain due to fusion event.PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
PTPRD-CDC37L1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTPRD

GO:0099545

trans-synaptic signaling by trans-synaptic complex

21926414

HgenePTPRD

GO:0099560

synaptic membrane adhesion

23345436

HgenePTPRD

GO:1905606

regulation of presynapse assembly

21926414


check buttonFusion gene breakpoints across PTPRD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CDC37L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0174-01APTPRDchr9

8404537

-CDC37L1chr9

4697096

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000360074PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+480142748546921535
ENST00000360074PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+706642748547791564
ENST00000537002PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+361030838535011138
ENST00000537002PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+587530838535881167
ENST00000397617PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+361930928535101141
ENST00000397617PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+588430928535971170
ENST00000358503PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+477442478546651526
ENST00000358503PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+703942478547521555
ENST00000397611PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+361030838535011138
ENST00000397611PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+587530838535881167
ENST00000355233PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+362230958535131142
ENST00000355233PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+588730958536001171
ENST00000356435PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+484343168847341548
ENST00000356435PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+710843168848211577
ENST00000486161PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+356730403334581141
ENST00000486161PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+583230403335451170
ENST00000397606PTPRDchr98404537-ENST00000381858CDC37L1chr94697096+356730403334581141
ENST00000397606PTPRDchr98404537-ENST00000381854CDC37L1chr94697096+583230403335451170

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360074ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0004070940.99959296
ENST00000360074ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001325120.99986744
ENST00000537002ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0003978020.99960226
ENST00000537002ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001194650.99988055
ENST00000397617ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0003682260.99963176
ENST00000397617ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001231450.99987686
ENST00000358503ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0003665790.99963343
ENST00000358503ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001782810.9998217
ENST00000397611ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0003834350.9996165
ENST00000397611ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001259450.999874
ENST00000355233ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.000382740.9996172
ENST00000355233ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001373850.99986255
ENST00000356435ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0003894320.9996106
ENST00000356435ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001334520.9998665
ENST00000486161ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0002840850.99971586
ENST00000486161ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+9.57E-050.9999043
ENST00000397606ENST00000381858PTPRDchr98404537-CDC37L1chr94697096+0.0002887150.9997112
ENST00000397606ENST00000381854PTPRDchr98404537-CDC37L1chr94697096+0.0001155360.9998845

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>70342_70342_1_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000355233_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1171AA_BP=1003
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVL
LSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMIT
VQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFT
NKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSSKPDRKRAESDSR
KSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVI
AYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQ
KAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDT

--------------------------------------------------------------

>70342_70342_2_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000355233_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1142AA_BP=1003
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVL
LSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMIT
VQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFT
NKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSSKPDRKRAESDSR
KSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVI
AYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQ

--------------------------------------------------------------

>70342_70342_3_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000356435_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1577AA_BP=1409
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSST
SILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGP
PRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYT
TKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR
LSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGL
KPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVN
LKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEM
ELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMD
LDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELAD
HIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILW
CFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPH

--------------------------------------------------------------

>70342_70342_4_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000356435_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1548AA_BP=1409
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSST
SILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGP
PRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYT
TKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR
LSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGL
KPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVN
LKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEM
ELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMD
LDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELAD
HIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILW
CFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPH

--------------------------------------------------------------

>70342_70342_5_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000358503_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1555AA_BP=1387
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT
PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELY
KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM
DPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY
ELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEK
QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS
VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGK
PRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEE
VPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYS
PSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQ
HRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREV
ELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLA
VVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP
GQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVV
MQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYS

--------------------------------------------------------------

>70342_70342_6_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000358503_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1526AA_BP=1387
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT
PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELY
KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM
DPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY
ELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEK
QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS
VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGK
PRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEE
VPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYS
PSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQ
HRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREV
ELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLA
VVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDP
GQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVV

--------------------------------------------------------------

>70342_70342_7_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000360074_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1564AA_BP=1396
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT
PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELY
KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM
DPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY
ELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEK
QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS
VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLV
STTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEM
VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAH
TSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTN
RGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKR
RSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGL
IWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF
SQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALM
EQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLP

--------------------------------------------------------------

>70342_70342_8_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000360074_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1535AA_BP=1396
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAEDLT
PEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELY
KEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM
DPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANY
ELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEK
QNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS
VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLV
STTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEM
VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAH
TSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTN
RGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKR
RSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGL
IWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKF
SQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALM
EQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLP

--------------------------------------------------------------

>70342_70342_9_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397606_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1170AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAE
DLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE
ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVY
YTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI
ANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYN
SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANE
NIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEY
VFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHP
TDPVELRRLNFQTPGSDDSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK
AKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV

--------------------------------------------------------------

>70342_70342_10_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397606_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1141AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAE
DLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE
ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVY
YTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI
ANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYN
SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANE
NIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEY
VFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHP
TDPVELRRLNFQTPGSDDSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK

--------------------------------------------------------------

>70342_70342_11_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397611_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1167AA_BP=999
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV
KWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ
HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQ
IQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWT
PPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSW
EIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQL
PEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQ
LQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSI
PNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDH
SRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKA

--------------------------------------------------------------

>70342_70342_12_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397611_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1138AA_BP=999
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV
KWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ
HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQ
IQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWT
PPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSW
EIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQL
PEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQ
LQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRKSSI
PNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDH
SRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKA

--------------------------------------------------------------

>70342_70342_13_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397617_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1170AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSVSIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAE
DLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE
ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVY
YTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI
ANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYN
SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANE
NIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEY
VFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHP
TDPVELRRLNFQTPGSDDSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK
AKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV

--------------------------------------------------------------

>70342_70342_14_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000397617_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1141AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSVSIGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLGAE
DLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSE
ELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVY
YTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTI
ANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYN
SAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANE
NIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQLQSGQEY
VFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKRAESDSRKSSIPNNKEIPSHHP
TDPVELRRLNFQTPGSDDSGYPGNLHSSSMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK

--------------------------------------------------------------

>70342_70342_15_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000486161_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1170AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVL
LSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMIT
VQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFT
NKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRK
SSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK
AKAEEEGYFEAFKNELEAFKSRVRLYSQSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSISTALCSLNSVVHKEDDEPKMMDTV

--------------------------------------------------------------

>70342_70342_16_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000486161_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1141AA_BP=1002
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSESIGGTPIRGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRELREVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPM
PYVKWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYY
IIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP
NGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILL
SWTPPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVL
LSWEIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMIT
VQLPEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFT
NKQLQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKSKPDRKRAESDSRK
SSIPNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA
YDHSRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQK

--------------------------------------------------------------

>70342_70342_17_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000537002_CDC37L1_chr9_4697096_ENST00000381854_length(amino acids)=1167AA_BP=999
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGRVFHTGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVNRKVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV
KWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ
HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQ
IQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWT
PPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSW
EIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQL
PEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQ
LQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKPYRKRAESDSRKSSI
PNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDH
SRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKA

--------------------------------------------------------------

>70342_70342_18_PTPRD-CDC37L1_PTPRD_chr9_8404537_ENST00000537002_CDC37L1_chr9_4697096_ENST00000381858_length(amino acids)=1138AA_BP=999
MLPSCRMVHVARLLLLLLTFFLRTDAETPPRFTRTPVDQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRI
QPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGNPDPEITWFKDFLPVDTSNNNGR
IKQLRSGRVFHTGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVNRKVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYV
KWMLGAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQ
HKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQ
IQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWT
PPRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSW
EIPENYNSAMPFKILYDDGKMVEEVDGRATQKLIVNLKPEKSYSFVLTNRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQL
PEVPANENIKGYYIIIVPLKKSRGKFIKPWESPDEMELDELLKEISRKRRSIRYGREVELKPYIAAHFDVLPTEFTLGDDKHYGGFTNKQ
LQSGQEYVFFVLAVMEHAESKMYATSPYSDPVVSMDLDPQPITDEEEGLIWVVGPVLAVVFIICIVIAILLYKRKPYRKRAESDSRKSSI
PNNKEIPSHHPTDPVELRRLNFQTPGMASHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDH
SRVLLSAIEGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNVDPRGCFRLFFQKAKA

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:8404537/chr9:4697096)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CDC37L1

Q7L3B6

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131126_224997.33333333333341507.0DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131236_318997.33333333333341507.0DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-213124_114997.33333333333341507.0DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131325_415997.33333333333341507.0DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131420_516997.33333333333341507.0DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131518_607997.33333333333341507.0DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131612_709997.33333333333341507.0DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131714_822997.33333333333341507.0DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131823_916997.33333333333341507.0DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351020_11061403.33333333333331913.0DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535126_2241403.33333333333331913.0DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535236_3181403.33333333333331913.0DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-253524_1141403.33333333333331913.0DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535325_4151403.33333333333331913.0DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535420_5161403.33333333333331913.0DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535518_6071403.33333333333331913.0DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535612_7091403.33333333333331913.0DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535714_8221403.33333333333331913.0DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535823_9161403.33333333333331913.0DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-2535921_10161403.33333333333331913.0DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431020_11061403.33333333333331913.0DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343126_2241403.33333333333331913.0DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343236_3181403.33333333333331913.0DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-334324_1141403.33333333333331913.0DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343325_4151403.33333333333331913.0DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343420_5161403.33333333333331913.0DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343518_6071403.33333333333331913.0DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343612_7091403.33333333333331913.0DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343714_8221403.33333333333331913.0DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343823_9161403.33333333333331913.0DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-3343921_10161403.33333333333331913.0DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929126_224996.33333333333341506.0DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929236_318996.33333333333341506.0DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-192924_114996.33333333333341506.0DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929325_415996.33333333333341506.0DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929420_516996.33333333333341506.0DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929518_607996.33333333333341506.0DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929612_709996.33333333333341506.0DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929714_822996.33333333333341506.0DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929823_916996.33333333333341506.0DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131126_224996.33333333333341506.0DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131236_318996.33333333333341506.0DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-213124_114996.33333333333341506.0DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131325_415996.33333333333341506.0DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131420_516996.33333333333341506.0DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131518_607996.33333333333341506.0DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131612_709996.33333333333341506.0DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131714_822996.33333333333341506.0DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131823_916996.33333333333341506.0DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361020_11061403.33333333333331952.3333333333333DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536126_2241403.33333333333331952.3333333333333DomainNote=Ig-like C2-type 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536236_3181403.33333333333331952.3333333333333DomainNote=Ig-like C2-type 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-253624_1141403.33333333333331952.3333333333333DomainNote=Ig-like C2-type 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536325_4151403.33333333333331952.3333333333333DomainFibronectin type-III 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536420_5161403.33333333333331952.3333333333333DomainFibronectin type-III 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536518_6071403.33333333333331952.3333333333333DomainFibronectin type-III 3
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536612_7091403.33333333333331952.3333333333333DomainFibronectin type-III 4
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536714_8221403.33333333333331952.3333333333333DomainFibronectin type-III 5
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536823_9161403.33333333333331952.3333333333333DomainFibronectin type-III 6
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-2536921_10161403.33333333333331952.3333333333333DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-253521_12651403.33333333333331913.0Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-334321_12651403.33333333333331913.0Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-253621_12651403.33333333333331952.3333333333333Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351266_12901403.33333333333331913.0TransmembraneHelical
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431266_12901403.33333333333331913.0TransmembraneHelical
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361266_12901403.33333333333331952.3333333333333TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311020_1106997.33333333333341507.0DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311357_1612997.33333333333341507.0DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311644_1903997.33333333333341507.0DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-2131921_1016997.33333333333341507.0DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351357_16121403.33333333333331913.0DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351644_19031403.33333333333331913.0DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431357_16121403.33333333333331913.0DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431644_19031403.33333333333331913.0DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291020_1106996.33333333333341506.0DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291357_1612996.33333333333341506.0DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291644_1903996.33333333333341506.0DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-1929921_1016996.33333333333341506.0DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311020_1106996.33333333333341506.0DomainFibronectin type-III 8
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311357_1612996.33333333333341506.0DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311644_1903996.33333333333341506.0DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-2131921_1016996.33333333333341506.0DomainFibronectin type-III 7
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361357_16121403.33333333333331952.3333333333333DomainTyrosine-protein phosphatase 1
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361644_19031403.33333333333331952.3333333333333DomainTyrosine-protein phosphatase 2
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311553_1559997.33333333333341507.0RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351553_15591403.33333333333331913.0RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431553_15591403.33333333333331913.0RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291553_1559996.33333333333341506.0RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311553_1559996.33333333333341506.0RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361553_15591403.33333333333331952.3333333333333RegionSubstrate binding
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311291_1912997.33333333333341507.0Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-213121_1265997.33333333333341507.0Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000356435-25351291_19121403.33333333333331913.0Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000381196-33431291_19121403.33333333333331913.0Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291291_1912996.33333333333341506.0Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-192921_1265996.33333333333341506.0Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311291_1912996.33333333333341506.0Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-213121_1265996.33333333333341506.0Topological domainExtracellular
HgenePTPRDchr9:8404537chr9:4697096ENST00000540109-25361291_19121403.33333333333331952.3333333333333Topological domainCytoplasmic
HgenePTPRDchr9:8404537chr9:4697096ENST00000355233-21311266_1290997.33333333333341507.0TransmembraneHelical
HgenePTPRDchr9:8404537chr9:4697096ENST00000397606-19291266_1290996.33333333333341506.0TransmembraneHelical
HgenePTPRDchr9:8404537chr9:4697096ENST00000486161-21311266_1290996.33333333333341506.0TransmembraneHelical
TgeneCDC37L1chr9:8404537chr9:4697096ENST000003818542784_122169.33333333333334338.0Coiled coilOntology_term=ECO:0000255
TgeneCDC37L1chr9:8404537chr9:4697096ENST00000381854272_171169.33333333333334338.0RegionNote=Self-association


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PTPRD
CDC37L1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to PTPRD-CDC37L1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PTPRD-CDC37L1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource