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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:PTPRK-EPB41L2

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: PTPRK-EPB41L2
	FusionPDB ID: 70438
	FusionGDB2.0 ID: 70438
		Hgene	Tgene
	Gene symbol	PTPRK	EPB41L2
	Gene ID	5796	2037
	Gene name	protein tyrosine phosphatase receptor type K	erythrocyte membrane protein band 4.1 like 2
	Synonyms	R-PTP-kappa	4.1-G\|4.1G
	Cytomap	6q22.33	6q23.1-q23.2
	Type of gene	protein-coding	protein-coding
	Description	receptor-type tyrosine-protein phosphatase kappadJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappaprotein-tyrosine phosphatase kappaprotein-tyrosine phospha	band 4.1-like protein 2erythrocyte membrane protein band 4.1 like-protein 2generally expressed protein 4.1
	Modification date	20200322	20200313
	UniProtAcc	.	O43491
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000368207, ENST00000368210, ENST00000368213, ENST00000368215, ENST00000368226, ENST00000368227, ENST00000525459, ENST00000532331, ENST00000524481,	ENST00000337057, ENST00000368128, ENST00000392427, ENST00000445890, ENST00000524581, ENST00000525193, ENST00000525271, ENST00000527411, ENST00000527659, ENST00000528282, ENST00000529208, ENST00000530148, ENST00000530481, ENST00000530757, ENST00000531410,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	36 X 18 X 16=10368	10 X 9 X 8=720
	# samples	48	10
	** MAII score	log2(48/10368*10)=-4.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/720*10)=-2.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: PTPRK [Title/Abstract] AND EPB41L2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	EPB41L2(131276245)-PTPRK(128330413), # samples:2 PTPRK(128841404)-EPB41L2(131184858), # samples:2
Anticipated loss of major functional domain due to fusion event.	EPB41L2-PTPRK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PTPRK-EPB41L2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PTPRK-EPB41L2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. PTPRK-EPB41L2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. PTPRK-EPB41L2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. EPB41L2-PTPRK seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	PTPRK	GO:0006470	protein dephosphorylation	16263724
Hgene	PTPRK	GO:0007165	signal transduction	16849327
Hgene	PTPRK	GO:0007179	transforming growth factor beta receptor signaling pathway	15899872
Hgene	PTPRK	GO:0008285	negative regulation of cell proliferation	15899872\|18276111
Hgene	PTPRK	GO:0010839	negative regulation of keratinocyte proliferation	16263724
Hgene	PTPRK	GO:0030336	negative regulation of cell migration	18276111
Hgene	PTPRK	GO:0034394	protein localization to cell surface	18276111
Hgene	PTPRK	GO:0034614	cellular response to reactive oxygen species	16849327
Hgene	PTPRK	GO:0034644	cellular response to UV	16849327
Hgene	PTPRK	GO:0045786	negative regulation of cell cycle	15899872
Hgene	PTPRK	GO:0045892	negative regulation of transcription, DNA-templated	18276111

Fusion gene breakpoints across PTPRK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EPB41L2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	COAD	TCGA-CM-6164-01A	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-
ChimerDB4	COAD	TCGA-CM-6164-01A	PTPRK	chr6	128841404	-	EPB41L2	chr6	131191266	-

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1862	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1862	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1862	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1862	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1859	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1859	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1852	416	443	0	148
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1852	416	443	0	148
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	1074	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	1027	416	443	0	148
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	605	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	605	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	605	416	532	2	177
ENST00000368226	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1862	416	532	2	177
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1913	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1913	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1913	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1913	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1910	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1910	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1903	467	494	0	165
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1903	467	494	0	165
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	1125	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	1078	467	494	0	165
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	656	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	656	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	656	467	583	2	194
ENST00000368227	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1913	467	583	2	194
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1664	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1664	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1664	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1664	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1661	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1661	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1654	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1654	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	876	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	829	218	2	406	134
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	407	218	2	406	135
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	407	218	2	406	135
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	407	218	2	406	135
ENST00000532331	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1664	218	2	406	134
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1768	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1768	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1761	325	109	513	134
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1761	325	109	513	134
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	983	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	936	325	109	513	134
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368213	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1804	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1804	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1804	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1804	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1801	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1801	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1794	358	142	546	134
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1794	358	142	546	134
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	1016	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	969	358	142	546	134
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	547	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	547	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	547	358	474	1	158
ENST00000368210	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1804	358	474	1	158
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1546	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1546	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1546	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1546	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1543	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1543	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1536	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1536	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	758	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	711	100	10	288	92
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	289	100	10	288	93
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	289	100	10	288	93
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	289	100	10	288	93
ENST00000368215	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1546	100	10	288	92
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1768	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1768	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1761	325	109	513	134
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1761	325	109	513	134
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	983	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	936	325	109	513	134
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	514	325	441	1	147
ENST00000368207	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1771	325	441	1	147
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000528282	EPB41L2	chr6	131184858	-	1775	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000530481	EPB41L2	chr6	131184858	-	1775	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000445890	EPB41L2	chr6	131184858	-	1775	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000337057	EPB41L2	chr6	131184858	-	1775	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000530757	EPB41L2	chr6	131184858	-	1772	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000392427	EPB41L2	chr6	131184858	-	1772	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000368128	EPB41L2	chr6	131184858	-	1765	329	113	517	134
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000527411	EPB41L2	chr6	131184858	-	1765	329	113	517	134
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000524581	EPB41L2	chr6	131184858	-	987	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000525271	EPB41L2	chr6	131184858	-	940	329	113	517	134
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000525193	EPB41L2	chr6	131184858	-	518	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000527659	EPB41L2	chr6	131184858	-	518	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000529208	EPB41L2	chr6	131184858	-	518	329	445	2	148
ENST00000525459	PTPRK	chr6	128841404	-	ENST00000531410	EPB41L2	chr6	131184858	-	1775	329	445	2	148

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000368226	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81163955	0.18836042
ENST00000368226	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81163955	0.18836042
ENST00000368226	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81163955	0.18836042
ENST00000368226	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81163955	0.18836042
ENST00000368226	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81293565	0.18706441
ENST00000368226	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81293565	0.18706441
ENST00000368226	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7702305	0.22976956
ENST00000368226	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.6836738	0.31632617
ENST00000368226	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7579967	0.24200332
ENST00000368226	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.71465904	0.28534096
ENST00000368226	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.16293922	0.8370608
ENST00000368226	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.16293922	0.8370608
ENST00000368226	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.16293922	0.8370608
ENST00000368226	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81163955	0.18836042
ENST00000368227	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.91842395	0.08157608
ENST00000368227	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.91842395	0.08157608
ENST00000368227	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.91842395	0.08157608
ENST00000368227	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.91842395	0.08157608
ENST00000368227	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.9120854	0.08791456
ENST00000368227	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.9120854	0.08791456
ENST00000368227	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.90696716	0.093032904
ENST00000368227	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8899849	0.110015094
ENST00000368227	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.83569854	0.16430144
ENST00000368227	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.79147226	0.20852771
ENST00000368227	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.28092802	0.71907204
ENST00000368227	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.28092802	0.71907204
ENST00000368227	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.28092802	0.71907204
ENST00000368227	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.91842395	0.08157608
ENST00000532331	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7849234	0.21507667
ENST00000532331	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7849234	0.21507667
ENST00000532331	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7849234	0.21507667
ENST00000532331	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7849234	0.21507667
ENST00000532331	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7862934	0.21370658
ENST00000532331	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7862934	0.21370658
ENST00000532331	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.74425673	0.25574327
ENST00000532331	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7159159	0.28408408
ENST00000532331	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.86069995	0.13930008
ENST00000532331	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8557539	0.14424612
ENST00000532331	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.31322715	0.6867728
ENST00000532331	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.31322715	0.6867728
ENST00000532331	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.31322715	0.6867728
ENST00000532331	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7849234	0.21507667
ENST00000368213	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368213	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368213	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368213	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368213	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78018975	0.21981029
ENST00000368213	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78018975	0.21981029
ENST00000368213	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.71590346	0.28409654
ENST00000368213	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.637343	0.36265704
ENST00000368213	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8260221	0.1739779
ENST00000368213	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8041298	0.1958702
ENST00000368213	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368213	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368213	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368213	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368210	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.89912164	0.100878365
ENST00000368210	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.89912164	0.100878365
ENST00000368210	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.89912164	0.100878365
ENST00000368210	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.89912164	0.100878365
ENST00000368210	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8967218	0.10327828
ENST00000368210	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8967218	0.10327828
ENST00000368210	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8927957	0.10720439
ENST00000368210	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.87422824	0.12577179
ENST00000368210	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.81133246	0.18866757
ENST00000368210	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78568584	0.2143142
ENST00000368210	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.21622497	0.78377503
ENST00000368210	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.21622497	0.78377503
ENST00000368210	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.21622497	0.78377503
ENST00000368210	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.89912164	0.100878365
ENST00000368215	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92845434	0.0715457
ENST00000368215	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92845434	0.0715457
ENST00000368215	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92845434	0.0715457
ENST00000368215	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92845434	0.0715457
ENST00000368215	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92548305	0.074517004
ENST00000368215	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92548305	0.074517004
ENST00000368215	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8935351	0.10646493
ENST00000368215	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8976546	0.102345444
ENST00000368215	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.901382	0.09861798
ENST00000368215	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8751656	0.124834485
ENST00000368215	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.4203493	0.5796507
ENST00000368215	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.4203493	0.5796507
ENST00000368215	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.4203493	0.5796507
ENST00000368215	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.92845434	0.0715457
ENST00000368207	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368207	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368207	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368207	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000368207	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78018975	0.21981029
ENST00000368207	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78018975	0.21981029
ENST00000368207	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.71590346	0.28409654
ENST00000368207	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.637343	0.36265704
ENST00000368207	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8260221	0.1739779
ENST00000368207	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8041298	0.1958702
ENST00000368207	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368207	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368207	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.2631485	0.7368515
ENST00000368207	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.78720105	0.21279895
ENST00000525459	ENST00000528282	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8629968	0.1370032
ENST00000525459	ENST00000530481	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8629968	0.1370032
ENST00000525459	ENST00000445890	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8629968	0.1370032
ENST00000525459	ENST00000337057	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8629968	0.1370032
ENST00000525459	ENST00000530757	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.86248326	0.13751675
ENST00000525459	ENST00000392427	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.86248326	0.13751675
ENST00000525459	ENST00000368128	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7491678	0.2508322
ENST00000525459	ENST00000527411	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.747443	0.25255704
ENST00000525459	ENST00000524581	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.7742768	0.22572313
ENST00000525459	ENST00000525271	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.74087584	0.25912422
ENST00000525459	ENST00000525193	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.22959642	0.77040356
ENST00000525459	ENST00000527659	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.22959642	0.77040356
ENST00000525459	ENST00000529208	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.22959642	0.77040356
ENST00000525459	ENST00000531410	PTPRK	chr6	128841404	-	EPB41L2	chr6	131184858	-	0.8629968	0.1370032

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>70438_70438_1_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_2_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_3_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_4_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_5_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_6_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_7_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_8_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_9_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_10_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_11_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_12_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_13_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_14_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368207_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_15_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_16_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_17_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_18_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_19_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_20_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_21_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_22_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_23_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_24_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_25_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_26_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_27_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_28_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368210_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=158AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_29_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_30_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_31_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_32_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_33_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_34_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_35_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_36_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_37_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_38_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_39_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_40_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_41_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_42_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368213_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=147AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_43_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_44_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_45_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_46_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_47_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_48_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=93AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_49_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_50_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_51_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=93AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_52_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_53_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=93AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_54_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_55_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_56_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368215_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=92AA_BP=30
MRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVITGDGDIDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEG

--------------------------------------------------------------

>70438_70438_57_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_58_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=148AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_59_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_60_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_61_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_62_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_63_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=148AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_64_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=148AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_65_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_66_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_67_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_68_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_69_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_70_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368226_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=177AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_71_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_72_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=165AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_73_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_74_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_75_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_76_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_77_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=165AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_78_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=165AA_BP=
MFQKFHLLQSAENWPWADPRRGQGERSKSATKAGSAAAAVVSMPSLGEVSSSFAKSCRGDRREIHDGGAGRASRGEDGERTAARPPFFLL

--------------------------------------------------------------

>70438_70438_79_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_80_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_81_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_82_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_83_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_84_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000368227_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=194AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI
AAKSTTEERAGPRGVRTVRGQPPARPFSFFAVAKLPQGRKRRQRRRPAAAAALHARRRLLLLVKSYFARGGTGAEPGVTSPRGLRALLRN

--------------------------------------------------------------

>70438_70438_85_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_86_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_87_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_88_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_89_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_90_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_91_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_92_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=134AA_BP=72
MSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_93_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_94_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_95_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_96_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_97_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_98_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000525459_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=148AA_BP=1
MLSGFPDRLSQCLVMINISISCDHNAFLNSCFRNSTFYSLRRTGLGPIPGEAKERGARAPQKQAAPPPQSYPCRVWEKFQAALQRAAGGI

--------------------------------------------------------------

>70438_70438_99_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000337057_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_100_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000368128_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_101_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000392427_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_102_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000445890_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_103_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000524581_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_104_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000525193_length(amino acids)=135AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_105_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000525271_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_106_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000527411_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_107_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000527659_length(amino acids)=135AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_108_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000528282_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_109_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000529208_length(amino acids)=135AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_110_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000530481_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_111_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000530757_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

>70438_70438_112_PTPRK-EPB41L2_PTPRK_chr6_128841404_ENST00000532331_EPB41L2_chr6_131184858_ENST00000531410_length(amino acids)=134AA_BP=72
LSSHRPHPARPGPLLRRGFRGDPPGSSLQSCLKLLPNSAWIRLRRRRCLLLWRSCSSLLGLSWDRPKASSPQTVKGGISETRIEKRIVIT

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:131276245/chr6:128330413)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	EPB41L2 O43491
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127). {ECO:0000269\|PubMed:23870127}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000392427

611_676

611.0

933.0

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000392427

855_1005

611.0

933.0

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000445890

855_1005

685.0

980.3333333333334

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000525271

611_676

611.0

645.3333333333334

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000525271

855_1005

611.0

645.3333333333334

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000528282

855_1005

685.0

985.0

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000530481

855_1005

790.0

1111.3333333333333

Region

Note=C-terminal (CTD)

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

1173_1435

33.333333333333336

1447.0

Domain

Tyrosine-protein phosphatase 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

196_281

33.333333333333336

1447.0

Domain

Note=Ig-like C2-type

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

294_389

33.333333333333336

1447.0

Domain

Fibronectin type-III 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

31_194

33.333333333333336

1447.0

Domain

MAM

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

392_488

33.333333333333336

1447.0

Domain

Fibronectin type-III 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

491_595

33.333333333333336

1447.0

Domain

Fibronectin type-III 3

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

597_680

33.333333333333336

1447.0

Domain

Fibronectin type-III 4

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

887_1141

33.333333333333336

1447.0

Domain

Tyrosine-protein phosphatase 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

1173_1435

33.333333333333336

1440.0

Domain

Tyrosine-protein phosphatase 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

196_281

33.333333333333336

1440.0

Domain

Note=Ig-like C2-type

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

294_389

33.333333333333336

1440.0

Domain

Fibronectin type-III 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

31_194

33.333333333333336

1440.0

Domain

MAM

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

392_488

33.333333333333336

1440.0

Domain

Fibronectin type-III 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

491_595

33.333333333333336

1440.0

Domain

Fibronectin type-III 3

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

597_680

33.333333333333336

1440.0

Domain

Fibronectin type-III 4

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

887_1141

33.333333333333336

1440.0

Domain

Tyrosine-protein phosphatase 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

1173_1435

33.333333333333336

1441.0

Domain

Tyrosine-protein phosphatase 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

196_281

33.333333333333336

1441.0

Domain

Note=Ig-like C2-type

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

294_389

33.333333333333336

1441.0

Domain

Fibronectin type-III 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

31_194

33.333333333333336

1441.0

Domain

MAM

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

392_488

33.333333333333336

1441.0

Domain

Fibronectin type-III 2

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

491_595

33.333333333333336

1441.0

Domain

Fibronectin type-III 3

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

597_680

33.333333333333336

1441.0

Domain

Fibronectin type-III 4

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

887_1141

33.333333333333336

1441.0

Domain

Tyrosine-protein phosphatase 1

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

1082_1088

33.333333333333336

1447.0

Region

Substrate binding

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

1082_1088

33.333333333333336

1440.0

Region

Substrate binding

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

1082_1088

33.333333333333336

1441.0

Region

Substrate binding

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

27_752

33.333333333333336

1447.0

Topological domain

Extracellular

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

775_1439

33.333333333333336

1447.0

Topological domain

Cytoplasmic

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

27_752

33.333333333333336

1440.0

Topological domain

Extracellular

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

775_1439

33.333333333333336

1440.0

Topological domain

Cytoplasmic

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

27_752

33.333333333333336

1441.0

Topological domain

Extracellular

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

775_1439

33.333333333333336

1441.0

Topological domain

Cytoplasmic

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368213

753_774

33.333333333333336

1447.0

Transmembrane

Helical

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368215

753_774

33.333333333333336

1440.0

Transmembrane

Helical

Hgene

PTPRK

chr6:128841404

chr6:131184858

ENST00000368226

753_774

33.333333333333336

1441.0

Transmembrane

Helical

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000337057

218_499

943.0

1236.3333333333333

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000368128

218_499

943.0

1230.0

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000392427

218_499

611.0

933.0

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000445890

218_499

685.0

980.3333333333334

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000525271

218_499

611.0

645.3333333333334

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000528282

218_499

685.0

985.0

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000530481

218_499

790.0

1111.3333333333333

Domain

FERM

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000337057

502_610

943.0

1236.3333333333333

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000337057

611_676

943.0

1236.3333333333333

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000337057

855_1005

943.0

1236.3333333333333

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000368128

502_610

943.0

1230.0

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000368128

611_676

943.0

1230.0

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000368128

855_1005

943.0

1230.0

Region

Note=C-terminal (CTD)

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000392427

502_610

611.0

933.0

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000445890

502_610

685.0

980.3333333333334

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000445890

611_676

685.0

980.3333333333334

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000525271

502_610

611.0

645.3333333333334

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000528282

502_610

685.0

985.0

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000528282

611_676

685.0

985.0

Region

Note=Spectrin--actin-binding

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000530481

502_610

790.0

1111.3333333333333

Region

Note=Hydrophilic

Tgene

EPB41L2

chr6:128841404

chr6:131184858

ENST00000530481

611_676

790.0

1111.3333333333333

Region

Note=Spectrin--actin-binding

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
PTPRK
EPB41L2

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to PTPRK-EPB41L2

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to PTPRK-EPB41L2

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source