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Center for Computational Systems Medicine level2
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein Structure

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pLDDT scores

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Ramachandran Plot of Fusion Protein Structure

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:ATP1B1-NRG1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: ATP1B1-NRG1
FusionPDB ID: 7804
FusionGDB2.0 ID: 7804
HgeneTgene
Gene symbol

ATP1B1

NRG1

Gene ID

481

3084

Gene nameATPase Na+/K+ transporting subunit beta 1neuregulin 1
SynonymsATP1BARIA|GGF|GGF2|HGL|HRG|HRG1|HRGA|MST131|MSTP131|NDF|NRG1-IT2|SMDF
Cytomap

1q24.2

8p12

Type of geneprotein-codingprotein-coding
Descriptionsodium/potassium-transporting ATPase subunit beta-1ATPase, Na+/K+ transporting, beta 1 polypeptideBeta 1-subunit of Na(+),K(+)-ATPaseNa, K-ATPase beta-1 polypeptideadenosinetriphosphatasesodium pump subunit beta-1sodium-potassium ATPase subunit betapro-neuregulin-1, membrane-bound isoformacetylcholine receptor-inducing activityglial growth factor 2heregulin, alpha (45kD, ERBB2 p185-activator)neu differentiation factorpro-NRG1sensory and motor neuron derived factor
Modification date2020031320200320
UniProtAcc

P05026

Q02297

Ensembl transtripts involved in fusion geneENST idsENST00000367813, ENST00000367815, 
ENST00000367816, ENST00000499679, 
ENST00000520502, ENST00000523681, 
ENST00000539990, ENST00000287842, 
ENST00000287845, ENST00000338921, 
ENST00000341377, ENST00000356819, 
ENST00000405005, ENST00000519301, 
ENST00000520407, ENST00000521670, 
ENST00000523079, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score11 X 12 X 7=92425 X 17 X 14=5950
# samples 1627
** MAII scorelog2(16/924*10)=-2.5298209465287
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/5950*10)=-4.46185835603184
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: ATP1B1 [Title/Abstract] AND NRG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)ATP1B1(169080736)-NRG1(32453346), # samples:3
Anticipated loss of major functional domain due to fusion event.ATP1B1-NRG1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP1B1-NRG1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP1B1-NRG1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP1B1-NRG1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATP1B1

GO:0006883

cellular sodium ion homeostasis

10636900|19542013

HgeneATP1B1

GO:0030007

cellular potassium ion homeostasis

10636900|19542013

HgeneATP1B1

GO:0032781

positive regulation of ATPase activity

10636900

HgeneATP1B1

GO:0036376

sodium ion export across plasma membrane

10636900|19542013

HgeneATP1B1

GO:0046034

ATP metabolic process

23954377

HgeneATP1B1

GO:0050821

protein stabilization

10636900

HgeneATP1B1

GO:0072659

protein localization to plasma membrane

18522992

HgeneATP1B1

GO:0086009

membrane repolarization

19542013

HgeneATP1B1

GO:1901018

positive regulation of potassium ion transmembrane transporter activity

10636900

HgeneATP1B1

GO:1903278

positive regulation of sodium ion export across plasma membrane

10636900

HgeneATP1B1

GO:1903288

positive regulation of potassium ion import

10636900

HgeneATP1B1

GO:1990573

potassium ion import across plasma membrane

10636900|19542013

TgeneNRG1

GO:0003222

ventricular trabecula myocardium morphogenesis

17336907

TgeneNRG1

GO:0031334

positive regulation of protein complex assembly

10559227

TgeneNRG1

GO:0038127

ERBB signaling pathway

11389077

TgeneNRG1

GO:0038129

ERBB3 signaling pathway

27353365

TgeneNRG1

GO:0045892

negative regulation of transcription, DNA-templated

15073182

TgeneNRG1

GO:0051048

negative regulation of secretion

10559227

TgeneNRG1

GO:0060379

cardiac muscle cell myoblast differentiation

17336907

TgeneNRG1

GO:0060956

endocardial cell differentiation

17336907


check buttonFusion gene breakpoints across ATP1B1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NRG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-3A-A9I5-01AATP1B1chr1

169080736

-NRG1chr8

32453346

+
ChimerDB4PAADTCGA-3A-A9I5-01AATP1B1chr1

169080736

+NRG1chr8

32453346

+
ChimerDB4PAADTCGA-3A-A9I5ATP1B1chr1

169080736

+NRG1chr8

32453345

+
ChimerDB4PAADTCGA-3A-A9I5ATP1B1chr1

169080736

+NRG1chr8

32453346

+
ChimerKB4..ATP1B1chr1

169080607

+NRG1chr8

169080607

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367816ATP1B1chr1169080736+ENST00000519301NRG1chr832453346+24947555292490653
ENST00000367816ATP1B1chr1169080736+ENST00000520407NRG1chr832453346+17357555291278249
ENST00000367816ATP1B1chr1169080736+ENST00000523079NRG1chr832453346+24977555291917462
ENST00000367816ATP1B1chr1169080736+ENST00000338921NRG1chr832453346+32307555292601690
ENST00000367816ATP1B1chr1169080736+ENST00000356819NRG1chr832453346+32217555292592687
ENST00000367816ATP1B1chr1169080736+ENST00000287845NRG1chr832453346+31197555292490653
ENST00000367816ATP1B1chr1169080736+ENST00000341377NRG1chr832453346+326575513982636412
ENST00000367816ATP1B1chr1169080736+ENST00000287842NRG1chr832453346+26787555292568679
ENST00000367816ATP1B1chr1169080736+ENST00000521670NRG1chr832453346+23167555292043504
ENST00000367816ATP1B1chr1169080736+ENST00000405005NRG1chr832453346+26477555292577682
ENST00000367815ATP1B1chr1169080736+ENST00000519301NRG1chr832453346+24727335072468653
ENST00000367815ATP1B1chr1169080736+ENST00000520407NRG1chr832453346+17137335071256249
ENST00000367815ATP1B1chr1169080736+ENST00000523079NRG1chr832453346+24757335071895462
ENST00000367815ATP1B1chr1169080736+ENST00000338921NRG1chr832453346+32087335072579690
ENST00000367815ATP1B1chr1169080736+ENST00000356819NRG1chr832453346+31997335072570687
ENST00000367815ATP1B1chr1169080736+ENST00000287845NRG1chr832453346+30977335072468653
ENST00000367815ATP1B1chr1169080736+ENST00000341377NRG1chr832453346+324373313762614412
ENST00000367815ATP1B1chr1169080736+ENST00000287842NRG1chr832453346+26567335072546679
ENST00000367815ATP1B1chr1169080736+ENST00000521670NRG1chr832453346+22947335072021504
ENST00000367815ATP1B1chr1169080736+ENST00000405005NRG1chr832453346+26257335072555682
ENST00000499679ATP1B1chr1169080736+ENST00000519301NRG1chr832453346+20312922012027608
ENST00000499679ATP1B1chr1169080736+ENST00000520407NRG1chr832453346+1272292201815204
ENST00000499679ATP1B1chr1169080736+ENST00000523079NRG1chr832453346+20342922011454417
ENST00000499679ATP1B1chr1169080736+ENST00000338921NRG1chr832453346+27672922012138645
ENST00000499679ATP1B1chr1169080736+ENST00000356819NRG1chr832453346+27582922012129642
ENST00000499679ATP1B1chr1169080736+ENST00000287845NRG1chr832453346+26562922012027608
ENST00000499679ATP1B1chr1169080736+ENST00000341377NRG1chr832453346+28022929352173412
ENST00000499679ATP1B1chr1169080736+ENST00000287842NRG1chr832453346+22152922012105634
ENST00000499679ATP1B1chr1169080736+ENST00000521670NRG1chr832453346+18532922011580459
ENST00000499679ATP1B1chr1169080736+ENST00000405005NRG1chr832453346+21842922012114637
ENST00000367813ATP1B1chr1169080736+ENST00000519301NRG1chr832453346+1974235241970648
ENST00000367813ATP1B1chr1169080736+ENST00000520407NRG1chr832453346+121523524758244
ENST00000367813ATP1B1chr1169080736+ENST00000523079NRG1chr832453346+1977235241397457
ENST00000367813ATP1B1chr1169080736+ENST00000338921NRG1chr832453346+2710235242081685
ENST00000367813ATP1B1chr1169080736+ENST00000356819NRG1chr832453346+2701235242072682
ENST00000367813ATP1B1chr1169080736+ENST00000287845NRG1chr832453346+2599235241970648
ENST00000367813ATP1B1chr1169080736+ENST00000341377NRG1chr832453346+27452358782116412
ENST00000367813ATP1B1chr1169080736+ENST00000287842NRG1chr832453346+2158235242048674
ENST00000367813ATP1B1chr1169080736+ENST00000521670NRG1chr832453346+1796235241523499
ENST00000367813ATP1B1chr1169080736+ENST00000405005NRG1chr832453346+2127235242057677
ENST00000367816ATP1B1chr1169080736+ENST00000519301NRG1chr832453345+24947555292490653
ENST00000367816ATP1B1chr1169080736+ENST00000520407NRG1chr832453345+17357555291278249
ENST00000367816ATP1B1chr1169080736+ENST00000523079NRG1chr832453345+24977555291917462
ENST00000367816ATP1B1chr1169080736+ENST00000338921NRG1chr832453345+32307555292601690
ENST00000367816ATP1B1chr1169080736+ENST00000356819NRG1chr832453345+32217555292592687
ENST00000367816ATP1B1chr1169080736+ENST00000287845NRG1chr832453345+31197555292490653
ENST00000367816ATP1B1chr1169080736+ENST00000341377NRG1chr832453345+326575513982636412
ENST00000367816ATP1B1chr1169080736+ENST00000287842NRG1chr832453345+26787555292568679
ENST00000367816ATP1B1chr1169080736+ENST00000521670NRG1chr832453345+23167555292043504
ENST00000367816ATP1B1chr1169080736+ENST00000405005NRG1chr832453345+26477555292577682
ENST00000367815ATP1B1chr1169080736+ENST00000519301NRG1chr832453345+24727335072468653
ENST00000367815ATP1B1chr1169080736+ENST00000520407NRG1chr832453345+17137335071256249
ENST00000367815ATP1B1chr1169080736+ENST00000523079NRG1chr832453345+24757335071895462
ENST00000367815ATP1B1chr1169080736+ENST00000338921NRG1chr832453345+32087335072579690
ENST00000367815ATP1B1chr1169080736+ENST00000356819NRG1chr832453345+31997335072570687
ENST00000367815ATP1B1chr1169080736+ENST00000287845NRG1chr832453345+30977335072468653
ENST00000367815ATP1B1chr1169080736+ENST00000341377NRG1chr832453345+324373313762614412
ENST00000367815ATP1B1chr1169080736+ENST00000287842NRG1chr832453345+26567335072546679
ENST00000367815ATP1B1chr1169080736+ENST00000521670NRG1chr832453345+22947335072021504
ENST00000367815ATP1B1chr1169080736+ENST00000405005NRG1chr832453345+26257335072555682
ENST00000499679ATP1B1chr1169080736+ENST00000519301NRG1chr832453345+20312922012027608
ENST00000499679ATP1B1chr1169080736+ENST00000520407NRG1chr832453345+1272292201815204
ENST00000499679ATP1B1chr1169080736+ENST00000523079NRG1chr832453345+20342922011454417
ENST00000499679ATP1B1chr1169080736+ENST00000338921NRG1chr832453345+27672922012138645
ENST00000499679ATP1B1chr1169080736+ENST00000356819NRG1chr832453345+27582922012129642
ENST00000499679ATP1B1chr1169080736+ENST00000287845NRG1chr832453345+26562922012027608
ENST00000499679ATP1B1chr1169080736+ENST00000341377NRG1chr832453345+28022929352173412
ENST00000499679ATP1B1chr1169080736+ENST00000287842NRG1chr832453345+22152922012105634
ENST00000499679ATP1B1chr1169080736+ENST00000521670NRG1chr832453345+18532922011580459
ENST00000499679ATP1B1chr1169080736+ENST00000405005NRG1chr832453345+21842922012114637
ENST00000367813ATP1B1chr1169080736+ENST00000519301NRG1chr832453345+1974235241970648
ENST00000367813ATP1B1chr1169080736+ENST00000520407NRG1chr832453345+121523524758244
ENST00000367813ATP1B1chr1169080736+ENST00000523079NRG1chr832453345+1977235241397457
ENST00000367813ATP1B1chr1169080736+ENST00000338921NRG1chr832453345+2710235242081685
ENST00000367813ATP1B1chr1169080736+ENST00000356819NRG1chr832453345+2701235242072682
ENST00000367813ATP1B1chr1169080736+ENST00000287845NRG1chr832453345+2599235241970648
ENST00000367813ATP1B1chr1169080736+ENST00000341377NRG1chr832453345+27452358782116412
ENST00000367813ATP1B1chr1169080736+ENST00000287842NRG1chr832453345+2158235242048674
ENST00000367813ATP1B1chr1169080736+ENST00000521670NRG1chr832453345+1796235241523499
ENST00000367813ATP1B1chr1169080736+ENST00000405005NRG1chr832453345+2127235242057677

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367816ENST00000519301ATP1B1chr1169080736+NRG1chr832453346+0.0136781570.9863218
ENST00000367816ENST00000520407ATP1B1chr1169080736+NRG1chr832453346+0.0286797270.9713202
ENST00000367816ENST00000523079ATP1B1chr1169080736+NRG1chr832453346+0.0202096590.97979033
ENST00000367816ENST00000338921ATP1B1chr1169080736+NRG1chr832453346+0.0065104690.9934895
ENST00000367816ENST00000356819ATP1B1chr1169080736+NRG1chr832453346+0.0047743840.99522555
ENST00000367816ENST00000287845ATP1B1chr1169080736+NRG1chr832453346+0.0052755380.99472445
ENST00000367816ENST00000341377ATP1B1chr1169080736+NRG1chr832453346+0.0120580150.9879419
ENST00000367816ENST00000287842ATP1B1chr1169080736+NRG1chr832453346+0.0087216520.99127835
ENST00000367816ENST00000521670ATP1B1chr1169080736+NRG1chr832453346+0.041166510.9588335
ENST00000367816ENST00000405005ATP1B1chr1169080736+NRG1chr832453346+0.0115884820.9884115
ENST00000367815ENST00000519301ATP1B1chr1169080736+NRG1chr832453346+0.0119007880.9880993
ENST00000367815ENST00000520407ATP1B1chr1169080736+NRG1chr832453346+0.0287038610.97129613
ENST00000367815ENST00000523079ATP1B1chr1169080736+NRG1chr832453346+0.0177480410.982252
ENST00000367815ENST00000338921ATP1B1chr1169080736+NRG1chr832453346+0.0056818050.9943182
ENST00000367815ENST00000356819ATP1B1chr1169080736+NRG1chr832453346+0.0042252510.9957748
ENST00000367815ENST00000287845ATP1B1chr1169080736+NRG1chr832453346+0.0046896460.99531037
ENST00000367815ENST00000341377ATP1B1chr1169080736+NRG1chr832453346+0.0107593290.9892407
ENST00000367815ENST00000287842ATP1B1chr1169080736+NRG1chr832453346+0.0075742230.9924258
ENST00000367815ENST00000521670ATP1B1chr1169080736+NRG1chr832453346+0.035402050.964598
ENST00000367815ENST00000405005ATP1B1chr1169080736+NRG1chr832453346+0.0100480280.989952
ENST00000499679ENST00000519301ATP1B1chr1169080736+NRG1chr832453346+0.0042231530.9957768
ENST00000499679ENST00000520407ATP1B1chr1169080736+NRG1chr832453346+0.0025374470.9974625
ENST00000499679ENST00000523079ATP1B1chr1169080736+NRG1chr832453346+0.0046442990.9953557
ENST00000499679ENST00000338921ATP1B1chr1169080736+NRG1chr832453346+0.0022248450.99777514
ENST00000499679ENST00000356819ATP1B1chr1169080736+NRG1chr832453346+0.0025371880.99746275
ENST00000499679ENST00000287845ATP1B1chr1169080736+NRG1chr832453346+0.001547560.9984524
ENST00000499679ENST00000341377ATP1B1chr1169080736+NRG1chr832453346+0.0041142320.9958858
ENST00000499679ENST00000287842ATP1B1chr1169080736+NRG1chr832453346+0.0049604560.9950395
ENST00000499679ENST00000521670ATP1B1chr1169080736+NRG1chr832453346+0.0145670140.98543304
ENST00000499679ENST00000405005ATP1B1chr1169080736+NRG1chr832453346+0.0063778210.99362224
ENST00000367813ENST00000519301ATP1B1chr1169080736+NRG1chr832453346+0.0041251040.99587494
ENST00000367813ENST00000520407ATP1B1chr1169080736+NRG1chr832453346+0.0035067780.99649316
ENST00000367813ENST00000523079ATP1B1chr1169080736+NRG1chr832453346+0.0042639570.995736
ENST00000367813ENST00000338921ATP1B1chr1169080736+NRG1chr832453346+0.0016118410.9983882
ENST00000367813ENST00000356819ATP1B1chr1169080736+NRG1chr832453346+0.0016087540.9983912
ENST00000367813ENST00000287845ATP1B1chr1169080736+NRG1chr832453346+0.0015404730.9984596
ENST00000367813ENST00000341377ATP1B1chr1169080736+NRG1chr832453346+0.0046366320.99536335
ENST00000367813ENST00000287842ATP1B1chr1169080736+NRG1chr832453346+0.0033731960.99662685
ENST00000367813ENST00000521670ATP1B1chr1169080736+NRG1chr832453346+0.0135272290.9864727
ENST00000367813ENST00000405005ATP1B1chr1169080736+NRG1chr832453346+0.0033745020.99662554
ENST00000367816ENST00000519301ATP1B1chr1169080736+NRG1chr832453345+0.0136781570.9863218
ENST00000367816ENST00000520407ATP1B1chr1169080736+NRG1chr832453345+0.0286797270.9713202
ENST00000367816ENST00000523079ATP1B1chr1169080736+NRG1chr832453345+0.0202096590.97979033
ENST00000367816ENST00000338921ATP1B1chr1169080736+NRG1chr832453345+0.0065104690.9934895
ENST00000367816ENST00000356819ATP1B1chr1169080736+NRG1chr832453345+0.0047743840.99522555
ENST00000367816ENST00000287845ATP1B1chr1169080736+NRG1chr832453345+0.0052755380.99472445
ENST00000367816ENST00000341377ATP1B1chr1169080736+NRG1chr832453345+0.0120580150.9879419
ENST00000367816ENST00000287842ATP1B1chr1169080736+NRG1chr832453345+0.0087216520.99127835
ENST00000367816ENST00000521670ATP1B1chr1169080736+NRG1chr832453345+0.041166510.9588335
ENST00000367816ENST00000405005ATP1B1chr1169080736+NRG1chr832453345+0.0115884820.9884115
ENST00000367815ENST00000519301ATP1B1chr1169080736+NRG1chr832453345+0.0119007880.9880993
ENST00000367815ENST00000520407ATP1B1chr1169080736+NRG1chr832453345+0.0287038610.97129613
ENST00000367815ENST00000523079ATP1B1chr1169080736+NRG1chr832453345+0.0177480410.982252
ENST00000367815ENST00000338921ATP1B1chr1169080736+NRG1chr832453345+0.0056818050.9943182
ENST00000367815ENST00000356819ATP1B1chr1169080736+NRG1chr832453345+0.0042252510.9957748
ENST00000367815ENST00000287845ATP1B1chr1169080736+NRG1chr832453345+0.0046896460.99531037
ENST00000367815ENST00000341377ATP1B1chr1169080736+NRG1chr832453345+0.0107593290.9892407
ENST00000367815ENST00000287842ATP1B1chr1169080736+NRG1chr832453345+0.0075742230.9924258
ENST00000367815ENST00000521670ATP1B1chr1169080736+NRG1chr832453345+0.035402050.964598
ENST00000367815ENST00000405005ATP1B1chr1169080736+NRG1chr832453345+0.0100480280.989952
ENST00000499679ENST00000519301ATP1B1chr1169080736+NRG1chr832453345+0.0042231530.9957768
ENST00000499679ENST00000520407ATP1B1chr1169080736+NRG1chr832453345+0.0025374470.9974625
ENST00000499679ENST00000523079ATP1B1chr1169080736+NRG1chr832453345+0.0046442990.9953557
ENST00000499679ENST00000338921ATP1B1chr1169080736+NRG1chr832453345+0.0022248450.99777514
ENST00000499679ENST00000356819ATP1B1chr1169080736+NRG1chr832453345+0.0025371880.99746275
ENST00000499679ENST00000287845ATP1B1chr1169080736+NRG1chr832453345+0.001547560.9984524
ENST00000499679ENST00000341377ATP1B1chr1169080736+NRG1chr832453345+0.0041142320.9958858
ENST00000499679ENST00000287842ATP1B1chr1169080736+NRG1chr832453345+0.0049604560.9950395
ENST00000499679ENST00000521670ATP1B1chr1169080736+NRG1chr832453345+0.0145670140.98543304
ENST00000499679ENST00000405005ATP1B1chr1169080736+NRG1chr832453345+0.0063778210.99362224
ENST00000367813ENST00000519301ATP1B1chr1169080736+NRG1chr832453345+0.0041251040.99587494
ENST00000367813ENST00000520407ATP1B1chr1169080736+NRG1chr832453345+0.0035067780.99649316
ENST00000367813ENST00000523079ATP1B1chr1169080736+NRG1chr832453345+0.0042639570.995736
ENST00000367813ENST00000338921ATP1B1chr1169080736+NRG1chr832453345+0.0016118410.9983882
ENST00000367813ENST00000356819ATP1B1chr1169080736+NRG1chr832453345+0.0016087540.9983912
ENST00000367813ENST00000287845ATP1B1chr1169080736+NRG1chr832453345+0.0015404730.9984596
ENST00000367813ENST00000341377ATP1B1chr1169080736+NRG1chr832453345+0.0046366320.99536335
ENST00000367813ENST00000287842ATP1B1chr1169080736+NRG1chr832453345+0.0033731960.99662685
ENST00000367813ENST00000521670ATP1B1chr1169080736+NRG1chr832453345+0.0135272290.9864727
ENST00000367813ENST00000405005ATP1B1chr1169080736+NRG1chr832453345+0.0033745020.99662554

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>7804_7804_1_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000287842_length(amino acids)=674AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAE
ELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVER
EAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYR
DSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPA
HDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLA

--------------------------------------------------------------

>7804_7804_2_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000287845_length(amino acids)=648AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS
HLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVV
AYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPS
HSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTP
SSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYE
PAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQE

--------------------------------------------------------------

>7804_7804_3_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000338921_length(amino acids)=685AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSK
NVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFL
RHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHP
QQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGED

--------------------------------------------------------------

>7804_7804_4_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_5_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000356819_length(amino acids)=682AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHL
GIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_6_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000405005_length(amino acids)=677AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHI
VEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPD
SYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHH
NPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQN

--------------------------------------------------------------

>7804_7804_7_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000519301_length(amino acids)=648AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS
HLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVV
AYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPS
HSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTP
SSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYE
PAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQE

--------------------------------------------------------------

>7804_7804_8_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000520407_length(amino acids)=244AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS

--------------------------------------------------------------

>7804_7804_9_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000521670_length(amino acids)=499AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHI
VEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPD

--------------------------------------------------------------

>7804_7804_10_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453345_ENST00000523079_length(amino acids)=457AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAE
ELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVER
EAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYR

--------------------------------------------------------------

>7804_7804_11_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000287842_length(amino acids)=674AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAE
ELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVER
EAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYR
DSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPA
HDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLA

--------------------------------------------------------------

>7804_7804_12_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000287845_length(amino acids)=648AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS
HLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVV
AYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPS
HSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTP
SSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYE
PAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQE

--------------------------------------------------------------

>7804_7804_13_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000338921_length(amino acids)=685AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSK
NVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFL
RHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHP
QQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGED

--------------------------------------------------------------

>7804_7804_14_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_15_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000356819_length(amino acids)=682AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHL
GIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_16_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000405005_length(amino acids)=677AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHI
VEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPD
SYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHH
NPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQN

--------------------------------------------------------------

>7804_7804_17_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000519301_length(amino acids)=648AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS
HLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVV
AYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPS
HSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTP
SSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYE
PAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQE

--------------------------------------------------------------

>7804_7804_18_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000520407_length(amino acids)=244AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTS

--------------------------------------------------------------

>7804_7804_19_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000521670_length(amino acids)=499AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQE
KAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHI
VEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPD

--------------------------------------------------------------

>7804_7804_20_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367813_NRG1_chr8_32453346_ENST00000523079_length(amino acids)=457AA_BP=70
MLTMGKRKCSPASQSLFLFQFQKMELKFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKL
VLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPAST
EGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAE
ELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVER
EAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYR

--------------------------------------------------------------

>7804_7804_21_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000287842_length(amino acids)=679AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET
PDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSF
HHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGI

--------------------------------------------------------------

>7804_7804_22_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000287845_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_23_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000338921_length(amino acids)=690AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVN
QYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKK
FDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDE

--------------------------------------------------------------

>7804_7804_24_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_25_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000356819_length(amino acids)=687AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYV
SKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNS
FLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDH
HPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVG

--------------------------------------------------------------

>7804_7804_26_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000405005_length(amino acids)=682AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_27_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000519301_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_28_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000520407_length(amino acids)=249AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS

--------------------------------------------------------------

>7804_7804_29_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000521670_length(amino acids)=504AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA

--------------------------------------------------------------

>7804_7804_30_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453345_ENST00000523079_length(amino acids)=462AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET

--------------------------------------------------------------

>7804_7804_31_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000287842_length(amino acids)=679AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET
PDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSF
HHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGI

--------------------------------------------------------------

>7804_7804_32_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000287845_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_33_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000338921_length(amino acids)=690AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVN
QYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKK
FDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDE

--------------------------------------------------------------

>7804_7804_34_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_35_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000356819_length(amino acids)=687AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYV
SKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNS
FLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDH
HPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVG

--------------------------------------------------------------

>7804_7804_36_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000405005_length(amino acids)=682AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_37_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000519301_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_38_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000520407_length(amino acids)=249AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS

--------------------------------------------------------------

>7804_7804_39_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000521670_length(amino acids)=504AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA

--------------------------------------------------------------

>7804_7804_40_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367815_NRG1_chr8_32453346_ENST00000523079_length(amino acids)=462AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET

--------------------------------------------------------------

>7804_7804_41_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000287842_length(amino acids)=679AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET
PDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSF
HHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGI

--------------------------------------------------------------

>7804_7804_42_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000287845_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_43_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000338921_length(amino acids)=690AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVN
QYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKK
FDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDE

--------------------------------------------------------------

>7804_7804_44_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_45_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000356819_length(amino acids)=687AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYV
SKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNS
FLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDH
HPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVG

--------------------------------------------------------------

>7804_7804_46_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000405005_length(amino acids)=682AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_47_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000519301_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_48_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000520407_length(amino acids)=249AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS

--------------------------------------------------------------

>7804_7804_49_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000521670_length(amino acids)=504AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA

--------------------------------------------------------------

>7804_7804_50_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453345_ENST00000523079_length(amino acids)=462AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET

--------------------------------------------------------------

>7804_7804_51_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000287842_length(amino acids)=679AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET
PDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSF
HHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGI

--------------------------------------------------------------

>7804_7804_52_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000287845_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_53_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000338921_length(amino acids)=690AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVN
QYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKK
FDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDE

--------------------------------------------------------------

>7804_7804_54_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_55_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000356819_length(amino acids)=687AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYV
SKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNS
FLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDH
HPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVG

--------------------------------------------------------------

>7804_7804_56_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000405005_length(amino acids)=682AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_57_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000519301_length(amino acids)=653AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS
TTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVG
IMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTV
TQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPV
DFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYET
TQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGR

--------------------------------------------------------------

>7804_7804_58_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000520407_length(amino acids)=249AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS

--------------------------------------------------------------

>7804_7804_59_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000521670_length(amino acids)=504AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA

--------------------------------------------------------------

>7804_7804_60_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000367816_NRG1_chr8_32453346_ENST00000523079_length(amino acids)=462AA_BP=75
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMAS
FYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSE
HIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARET

--------------------------------------------------------------

>7804_7804_61_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000287842_length(amino acids)=634AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHD
RLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSE
SHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPV
SSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRR
AKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQD

--------------------------------------------------------------

>7804_7804_62_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000287845_length(amino acids)=608AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT
GDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPP
PENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRL
NGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVT
PPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSN

--------------------------------------------------------------

>7804_7804_63_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000338921_length(amino acids)=645AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYC
KTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSW
SNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSP
KSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQ
EPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQ

--------------------------------------------------------------

>7804_7804_64_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_65_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000356819_length(amino acids)=642AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTK
KQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNG
HTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSP
PSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPV
KKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARL

--------------------------------------------------------------

>7804_7804_66_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000405005_length(amino acids)=637AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKK
LHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESI
LSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMS
PPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLAN
SRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIA

--------------------------------------------------------------

>7804_7804_67_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000519301_length(amino acids)=608AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT
GDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPP
PENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRL
NGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVT
PPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSN

--------------------------------------------------------------

>7804_7804_68_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000520407_length(amino acids)=204AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT

--------------------------------------------------------------

>7804_7804_69_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000521670_length(amino acids)=459AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKK
LHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESI
LSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERHNLIAELRRNKAHRSKCMQIQLSATHLRSS

--------------------------------------------------------------

>7804_7804_70_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453345_ENST00000523079_length(amino acids)=417AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHD
RLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSE

--------------------------------------------------------------

>7804_7804_71_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000287842_length(amino acids)=634AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHD
RLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSE
SHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPV
SSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRR
AKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIANQD

--------------------------------------------------------------

>7804_7804_72_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000287845_length(amino acids)=608AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT
GDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPP
PENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRL
NGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVT
PPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSN

--------------------------------------------------------------

>7804_7804_73_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000338921_length(amino acids)=645AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYC
KTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSW
SNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSP
KSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQ
EPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQ

--------------------------------------------------------------

>7804_7804_74_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000341377_length(amino acids)=412AA_BP=
MASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVI
SSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHA
RETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQF
SSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPF

--------------------------------------------------------------

>7804_7804_75_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000356819_length(amino acids)=642AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTK
KQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNG
HTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSP
PSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPV
KKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARL

--------------------------------------------------------------

>7804_7804_76_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000405005_length(amino acids)=637AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKK
LHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESI
LSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMS
PPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLAN
SRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDERVGEDTPFLGIQNPLAASLEATPAFRLADSRTNPAGRFSTQEEIQARLSSVIA

--------------------------------------------------------------

>7804_7804_77_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000519301_length(amino acids)=608AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT
GDRCQNYVMASFYKHLGIEFMEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPP
PENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRL
NGTGGPRECNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVT
PPRLREKKFDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSN

--------------------------------------------------------------

>7804_7804_78_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000520407_length(amino acids)=204AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFT

--------------------------------------------------------------

>7804_7804_79_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000521670_length(amino acids)=459AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMKVQNQEKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKK
LHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESI
LSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRECNSFLRHARETPDSYRDSPHSERHNLIAELRRNKAHRSKCMQIQLSATHLRSS

--------------------------------------------------------------

>7804_7804_80_ATP1B1-NRG1_ATP1B1_chr1_169080736_ENST00000499679_NRG1_chr8_32453346_ENST00000523079_length(amino acids)=417AA_BP=30
MAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCA
EKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHD
RLRQSLRSERNNMMNIANGPHHPNPPPENVQLVNQYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSE

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:169080736/chr8:32453346)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP1B1

P05026

NRG1

Q02297

FUNCTION: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. {ECO:0000269|PubMed:19694409}.; FUNCTION: Involved in cell adhesion and establishing epithelial cell polarity. {ECO:0000269|PubMed:19694409}.FUNCTION: Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development. Binds to ERBB4 (PubMed:10867024, PubMed:7902537). Binds to ERBB3 (PubMed:20682778). Acts as a ligand for integrins and binds (via EGF domain) to integrins ITGAV:ITGB3 or ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and ERRB3 are essential for NRG1-ERBB signaling. Induces the phosphorylation and activation of MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:20682778). Ligand-dependent ERBB4 endocytosis is essential for the NRG1-mediated activation of these kinases in neurons (By similarity). {ECO:0000250|UniProtKB:P43322, ECO:0000269|PubMed:10867024, ECO:0000269|PubMed:1348215, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:7902537}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367815+261_3475.33333333333333304.0Topological domainCytoplasmic
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367816+371_3475.33333333333333304.0Topological domainCytoplasmic
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367815+261_3475.33333333333333304.0Topological domainCytoplasmic
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367816+371_3475.33333333333333304.0Topological domainCytoplasmic
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367815+2635_6275.33333333333333304.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367816+3735_6275.33333333333333304.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367815+2635_6275.33333333333333304.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367816+3735_6275.33333333333333304.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneNRG1chr1:169080736chr8:32453345ENST00000287842012165_17733.333333333333336638.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000341377013165_17733.333333333333336525.3333333333334Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000356819013165_17733.333333333333336646.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000405005012165_17733.333333333333336641.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000519301011165_17712.333333333333334591.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST0000052050203165_1770.0297.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000521670013165_17733.333333333333336477.3333333333333Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000523079011165_17733.333333333333336421.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000287842012165_17733.333333333333336638.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000341377013165_17733.333333333333336525.3333333333334Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000356819013165_17733.333333333333336646.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000405005012165_17733.333333333333336641.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000519301011165_17712.333333333333334591.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST0000052050203165_1770.0297.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000521670013165_17733.333333333333336477.3333333333333Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST00000523079011165_17733.333333333333336421.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST00000287842012178_22233.333333333333336638.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000028784201237_12833.333333333333336638.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000341377013178_22233.333333333333336525.3333333333334DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000034137701337_12833.333333333333336525.3333333333334DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000356819013178_22233.333333333333336646.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000035681901337_12833.333333333333336646.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000405005012178_22233.333333333333336641.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000040500501237_12833.333333333333336641.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000519301011178_22212.333333333333334591.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000051930101137_12812.333333333333334591.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST0000052050203178_2220.0297.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST000005205020337_1280.0297.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000521670013178_22233.333333333333336477.3333333333333DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000052167001337_12833.333333333333336477.3333333333333DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000523079011178_22233.333333333333336421.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST0000052307901137_12833.333333333333336421.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000287842012178_22233.333333333333336638.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000028784201237_12833.333333333333336638.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000341377013178_22233.333333333333336525.3333333333334DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000034137701337_12833.333333333333336525.3333333333334DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000356819013178_22233.333333333333336646.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000035681901337_12833.333333333333336646.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000405005012178_22233.333333333333336641.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000040500501237_12833.333333333333336641.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000519301011178_22212.333333333333334591.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000051930101137_12812.333333333333334591.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST0000052050203178_2220.0297.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST000005205020337_1280.0297.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000521670013178_22233.333333333333336477.3333333333333DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000052167001337_12833.333333333333336477.3333333333333DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST00000523079011178_22233.333333333333336421.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST0000052307901137_12833.333333333333336421.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST00000287842012266_64033.333333333333336638.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000341377013266_64033.333333333333336525.3333333333334Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000356819013266_64033.333333333333336646.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000405005012266_64033.333333333333336641.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST0000051930101120_24212.333333333333334591.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST00000519301011266_64012.333333333333334591.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST0000052040705266_640248.33333333333334423.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST000005205020320_2420.0297.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000052050203266_6400.0297.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000521670013266_64033.333333333333336477.3333333333333Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000523079011266_64033.333333333333336421.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000287842012266_64033.333333333333336638.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000341377013266_64033.333333333333336525.3333333333334Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000356819013266_64033.333333333333336646.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000405005012266_64033.333333333333336641.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST0000051930101120_24212.333333333333334591.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST00000519301011266_64012.333333333333334591.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST0000052040705266_640248.33333333333334423.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST000005205020320_2420.0297.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000052050203266_6400.0297.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000521670013266_64033.333333333333336477.3333333333333Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453346ENST00000523079011266_64033.333333333333336421.0Topological domainCytoplasmic
TgeneNRG1chr1:169080736chr8:32453345ENST00000287842012243_26533.333333333333336638.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000341377013243_26533.333333333333336525.3333333333334TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000356819013243_26533.333333333333336646.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000405005012243_26533.333333333333336641.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000519301011243_26512.333333333333334591.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST0000052050203243_2650.0297.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000521670013243_26533.333333333333336477.3333333333333TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453345ENST00000523079011243_26533.333333333333336421.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000287842012243_26533.333333333333336638.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000341377013243_26533.333333333333336525.3333333333334TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000356819013243_26533.333333333333336646.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000405005012243_26533.333333333333336641.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000519301011243_26512.333333333333334591.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST0000052050203243_2650.0297.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000521670013243_26533.333333333333336477.3333333333333TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST00000523079011243_26533.333333333333336421.0TransmembraneHelical%3B Note%3DInternal signal sequence

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367815+26191_30375.33333333333333304.0RegionNote=immunoglobulin-like
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367816+37191_30375.33333333333333304.0RegionNote=immunoglobulin-like
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367815+26191_30375.33333333333333304.0RegionNote=immunoglobulin-like
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367816+37191_30375.33333333333333304.0RegionNote=immunoglobulin-like
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367815+2663_30375.33333333333333304.0Topological domainExtracellular
HgeneATP1B1chr1:169080736chr8:32453345ENST00000367816+3763_30375.33333333333333304.0Topological domainExtracellular
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367815+2663_30375.33333333333333304.0Topological domainExtracellular
HgeneATP1B1chr1:169080736chr8:32453346ENST00000367816+3763_30375.33333333333333304.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000052040705165_177248.33333333333334423.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453346ENST0000052040705165_177248.33333333333334423.0Compositional biasNote=Ser/Thr-rich
TgeneNRG1chr1:169080736chr8:32453345ENST0000052040705178_222248.33333333333334423.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453345ENST000005204070537_128248.33333333333334423.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453346ENST0000052040705178_222248.33333333333334423.0DomainEGF-like
TgeneNRG1chr1:169080736chr8:32453346ENST000005204070537_128248.33333333333334423.0DomainNote=Ig-like C2-type
TgeneNRG1chr1:169080736chr8:32453345ENST0000028784201220_24233.333333333333336638.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000034137701320_24233.333333333333336525.3333333333334Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000035681901320_24233.333333333333336646.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000040500501220_24233.333333333333336641.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST000005204070520_242248.33333333333334423.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000052167001320_24233.333333333333336477.3333333333333Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000052307901120_24233.333333333333336421.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000028784201220_24233.333333333333336638.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000034137701320_24233.333333333333336525.3333333333334Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000035681901320_24233.333333333333336646.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000040500501220_24233.333333333333336641.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST000005204070520_242248.33333333333334423.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000052167001320_24233.333333333333336477.3333333333333Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453346ENST0000052307901120_24233.333333333333336421.0Topological domainExtracellular
TgeneNRG1chr1:169080736chr8:32453345ENST0000052040705243_265248.33333333333334423.0TransmembraneHelical%3B Note%3DInternal signal sequence
TgeneNRG1chr1:169080736chr8:32453346ENST0000052040705243_265248.33333333333334423.0TransmembraneHelical%3B Note%3DInternal signal sequence


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Fusion Protein Structures

check button PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.
Fusion protein PDB link (fusion AA seq ID in FusionPDB)HgeneHchrHbpHstrandTgeneTchrTbpTstrandAA seqLen(AA seq)
PDB file >>>1413_ATP1B1_169080736_NRG1_32453346_ranked_0.pdbATP1B1169080736169080736ENST00000405005NRG1chr832453346+
MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPALPPRLKEMKSQESA
AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITG
MPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENVPMK
VQNQEKHSGEPFPEAEELYQKRVLTITGICIALLVVGIMCVVAYCKTKKQRKKLHDRLRQSLRSERNNMMNIANGPHHPNPPPENVQLVN
QYVSKNVISSEHIVEREAETSFSTSHYTSTAHHSTTVTQTPSHSWSNGHTESILSESHSVIVMSSVENSRHSSPTGGPRGRLNGTGGPRE
CNSFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVSMPSMAVSPFMEEERPLLLVTPPRLREKK
FDHHPQQFSSFHHNPAHDSNSLPASPLRIVEDEEYETTQEYEPAQEPVKKLANSRRAKRTKPNGHIANRLEVDSNTSSQSSNSESETEDE
690


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pLDDT score distribution

check button pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
ATP1B1_pLDDT.png
all structure
all structure
NRG1_pLDDT.png
all structure
all structure

check button pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.
all structure


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Ramachandran Plot of Fusion Protein Structure


check button Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.
Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
ATP1B1
NRG1all structure


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to ATP1B1-NRG1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to ATP1B1-NRG1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneNRG1C0036341Schizophrenia7CTD_human
TgeneNRG1C0005586Bipolar Disorder5PSYGENET
TgeneNRG1C0024809Marijuana Abuse3PSYGENET
TgeneNRG1C0011570Mental Depression2PSYGENET
TgeneNRG1C0011581Depressive disorder2PSYGENET
TgeneNRG1C0006142Malignant neoplasm of breast1CTD_human
TgeneNRG1C0006870Cannabis Dependence1PSYGENET
TgeneNRG1C0007621Neoplastic Cell Transformation1CTD_human
TgeneNRG1C0011616Contact Dermatitis1CTD_human
TgeneNRG1C0018801Heart failure1CTD_human
TgeneNRG1C0018802Congestive heart failure1CTD_human
TgeneNRG1C0019569Hirschsprung Disease1CTD_human
TgeneNRG1C0023212Left-Sided Heart Failure1CTD_human
TgeneNRG1C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneNRG1C0024121Lung Neoplasms1CTD_human
TgeneNRG1C0026650Movement Disorders1CTD_human
TgeneNRG1C0027626Neoplasm Invasiveness1CTD_human
TgeneNRG1C0030193Pain1CTD_human
TgeneNRG1C0032460Polycystic Ovary Syndrome1CTD_human
TgeneNRG1C0038358Gastric ulcer1CTD_human
TgeneNRG1C0085758Aganglionosis, Colonic1CTD_human
TgeneNRG1C0087031Juvenile-Onset Still Disease1CTD_human
TgeneNRG1C0162351Contact hypersensitivity1CTD_human
TgeneNRG1C0234230Pain, Burning1CTD_human
TgeneNRG1C0234238Ache1CTD_human
TgeneNRG1C0234254Radiating pain1CTD_human
TgeneNRG1C0235527Heart Failure, Right-Sided1CTD_human
TgeneNRG1C0236733Amphetamine-Related Disorders1CTD_human
TgeneNRG1C0236804Amphetamine Addiction1CTD_human
TgeneNRG1C0236807Amphetamine Abuse1CTD_human
TgeneNRG1C0242379Malignant neoplasm of lung1CTD_human
TgeneNRG1C0266487Etat Marbre1CTD_human
TgeneNRG1C0458257Pain, Splitting1CTD_human
TgeneNRG1C0458259Pain, Crushing1CTD_human
TgeneNRG1C0678222Breast Carcinoma1CTD_human
TgeneNRG1C0751407Pain, Migratory1CTD_human
TgeneNRG1C0751408Suffering, Physical1CTD_human
TgeneNRG1C0876994Cardiotoxicity1CTD_human
TgeneNRG1C1136382Sclerocystic Ovaries1CTD_human
TgeneNRG1C1257840Aganglionosis, Rectosigmoid Colon1CTD_human
TgeneNRG1C1257931Mammary Neoplasms, Human1CTD_human
TgeneNRG1C1458155Mammary Neoplasms1CTD_human
TgeneNRG1C1959583Myocardial Failure1CTD_human
TgeneNRG1C1961112Heart Decompensation1CTD_human
TgeneNRG1C3495559Juvenile arthritis1CTD_human
TgeneNRG1C3661523Congenital Intestinal Aganglionosis1CTD_human
TgeneNRG1C3714758Juvenile psoriatic arthritis1CTD_human
TgeneNRG1C4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
TgeneNRG1C4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human
TgeneNRG1C4704874Mammary Carcinoma, Human1CTD_human