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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:RSU1-ZMYND11

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: RSU1-ZMYND11
FusionPDB ID: 78498
FusionGDB2.0 ID: 78498
HgeneTgene
Gene symbol

RSU1

ZMYND11

Gene ID

6251

10771

Gene nameRas suppressor protein 1zinc finger MYND-type containing 11
SynonymsRSP-1BRAM1|BS69|MRD30
Cytomap

10p13

10p15.3

Type of geneprotein-codingprotein-coding
Descriptionras suppressor protein 1ras suppressor protein 1 variant 1ras suppressor protein 1 variant 2ras suppressor protein 1 variant 3ras suppressor protein 1 variant 5rsu-1zinc finger MYND domain-containing protein 11adenovirus 5 E1A-binding proteinbone morphogenetic protein receptor-associated molecule 1
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000345264, ENST00000377921, 
ENST00000602389, ENST00000464074, 
ENST00000473115, ENST00000309776, 
ENST00000381584, ENST00000381591, 
ENST00000381602, ENST00000381604, 
ENST00000381607, ENST00000397959, 
ENST00000397962, ENST00000402736, 
ENST00000403354, ENST00000509513, 
ENST00000535374, ENST00000545619, 
ENST00000558098, ENST00000602682, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 8 X 11=114410 X 8 X 7=560
# samples 1411
** MAII scorelog2(14/1144*10)=-3.03058831983342
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/560*10)=-2.34792330342031
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: RSU1 [Title/Abstract] AND ZMYND11 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)RSU1(16824033)-ZMYND11(294276), # samples:1
Anticipated loss of major functional domain due to fusion event.RSU1-ZMYND11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
RSU1-ZMYND11 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneZMYND11

GO:0051607

defense response to virus

26845565


check buttonFusion gene breakpoints across RSU1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZMYND11 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-7525-01ARSU1chr10

16824033

-ZMYND11chr10

294276

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000602389RSU1chr1016824033-ENST00000381602ZMYND11chr10294276+821191242670142
ENST00000602389RSU1chr1016824033-ENST00000397962ZMYND11chr10294276+2929191242772176
ENST00000602389RSU1chr1016824033-ENST00000309776ZMYND11chr10294276+2929191242772176
ENST00000602389RSU1chr1016824033-ENST00000509513ZMYND11chr10294276+823191242670142
ENST00000602389RSU1chr1016824033-ENST00000397959ZMYND11chr10294276+883191242772176
ENST00000602389RSU1chr1016824033-ENST00000381591ZMYND11chr10294276+2940191242772176
ENST00000602389RSU1chr1016824033-ENST00000403354ZMYND11chr10294276+773191242772177
ENST00000602389RSU1chr1016824033-ENST00000381607ZMYND11chr10294276+2929191242772176
ENST00000602389RSU1chr1016824033-ENST00000402736ZMYND11chr10294276+2937191242772176
ENST00000602389RSU1chr1016824033-ENST00000602682ZMYND11chr10294276+883191242772176
ENST00000602389RSU1chr1016824033-ENST00000381604ZMYND11chr10294276+1532191242772176
ENST00000602389RSU1chr1016824033-ENST00000381584ZMYND11chr10294276+1559191242772176
ENST00000602389RSU1chr1016824033-ENST00000558098ZMYND11chr10294276+823191242670142
ENST00000602389RSU1chr1016824033-ENST00000545619ZMYND11chr10294276+773191242772177
ENST00000602389RSU1chr1016824033-ENST00000535374ZMYND11chr10294276+875191242772176

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000602389ENST00000381602RSU1chr1016824033-ZMYND11chr10294276+0.0332867840.96671325
ENST00000602389ENST00000397962RSU1chr1016824033-ZMYND11chr10294276+0.0014365010.99856347
ENST00000602389ENST00000309776RSU1chr1016824033-ZMYND11chr10294276+0.0014365010.99856347
ENST00000602389ENST00000509513RSU1chr1016824033-ZMYND11chr10294276+0.0333131850.96668684
ENST00000602389ENST00000397959RSU1chr1016824033-ZMYND11chr10294276+0.0095370320.99046296
ENST00000602389ENST00000381591RSU1chr1016824033-ZMYND11chr10294276+0.0014608180.9985392
ENST00000602389ENST00000403354RSU1chr1016824033-ZMYND11chr10294276+0.0124060830.98759395
ENST00000602389ENST00000381607RSU1chr1016824033-ZMYND11chr10294276+0.0014365010.99856347
ENST00000602389ENST00000402736RSU1chr1016824033-ZMYND11chr10294276+0.0014438560.9985562
ENST00000602389ENST00000602682RSU1chr1016824033-ZMYND11chr10294276+0.0095370320.99046296
ENST00000602389ENST00000381604RSU1chr1016824033-ZMYND11chr10294276+0.0032400230.99675995
ENST00000602389ENST00000381584RSU1chr1016824033-ZMYND11chr10294276+0.0030874510.9969125
ENST00000602389ENST00000558098RSU1chr1016824033-ZMYND11chr10294276+0.0333131850.96668684
ENST00000602389ENST00000545619RSU1chr1016824033-ZMYND11chr10294276+0.0124060830.98759395
ENST00000602389ENST00000535374RSU1chr1016824033-ZMYND11chr10294276+0.0098530610.99014693

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>78498_78498_1_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000309776_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_2_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000381584_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_3_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000381591_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_4_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000381602_length(amino acids)=142AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_5_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000381604_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_6_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000381607_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_7_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000397959_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_8_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000397962_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_9_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000402736_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_10_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000403354_length(amino acids)=177AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_11_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000509513_length(amino acids)=142AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_12_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000535374_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_13_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000545619_length(amino acids)=177AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_14_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000558098_length(amino acids)=142AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

>78498_78498_15_RSU1-ZMYND11_RSU1_chr10_16824033_ENST00000602389_ZMYND11_chr10_294276_ENST00000602682_length(amino acids)=176AA_BP=
MPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTNDGVCQSMCHDKYTKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEKRQAVNKA

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:16824033/chr10:294276)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZMYND11chr10:16824033chr10:294276ENST000003097761115394_400369.0563.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000003816041115394_400369.0563.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST00000397959913394_400324.0518.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST00000602682812394_400324.0518.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000003097761115563_598369.0563.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003815911115563_598409.0603.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003816041115563_598369.0563.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST00000397959913563_598324.0518.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003979621115563_598409.0603.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST000005095131114563_598408.0568.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST000005580981013563_598409.0569.0Zinc fingerMYND-type
TgeneZMYND11chr10:16824033chr10:294276ENST00000602682812563_598324.0518.0Zinc fingerMYND-type

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-39110_13353.333333333333336278.0RepeatNote=LRR 4
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-39135_15653.333333333333336278.0RepeatNote=LRR 5
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-39158_17953.333333333333336278.0RepeatNote=LRR 6
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-39181_20253.333333333333336278.0RepeatNote=LRR 7
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-3941_6353.333333333333336278.0RepeatNote=LRR 1
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-3964_8553.333333333333336278.0RepeatNote=LRR 2
HgeneRSU1chr10:16824033chr10:294276ENST00000345264-3987_10953.333333333333336278.0RepeatNote=LRR 3
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-28110_13353.333333333333336278.0RepeatNote=LRR 4
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-28135_15653.333333333333336278.0RepeatNote=LRR 5
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-28158_17953.333333333333336278.0RepeatNote=LRR 6
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-28181_20253.333333333333336278.0RepeatNote=LRR 7
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-2841_6353.333333333333336278.0RepeatNote=LRR 1
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-2864_8553.333333333333336278.0RepeatNote=LRR 2
HgeneRSU1chr10:16824033chr10:294276ENST00000377921-2887_10953.333333333333336278.0RepeatNote=LRR 3
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-28110_1330.3333333333333333225.0RepeatNote=LRR 4
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-28135_1560.3333333333333333225.0RepeatNote=LRR 5
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-28158_1790.3333333333333333225.0RepeatNote=LRR 6
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-28181_2020.3333333333333333225.0RepeatNote=LRR 7
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-2841_630.3333333333333333225.0RepeatNote=LRR 1
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-2864_850.3333333333333333225.0RepeatNote=LRR 2
HgeneRSU1chr10:16824033chr10:294276ENST00000602389-2887_1090.3333333333333333225.0RepeatNote=LRR 3
TgeneZMYND11chr10:16824033chr10:294276ENST000003097761115168_238369.0563.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000003097761115280_331369.0563.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000003815911115168_238409.0603.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000003815911115280_331409.0603.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000003816041115168_238369.0563.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000003816041115280_331369.0563.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST00000397959913168_238324.0518.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST00000397959913280_331324.0518.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000003979621115168_238409.0603.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000003979621115280_331409.0603.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000005095131114168_238408.0568.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000005095131114280_331408.0568.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000005580981013168_238409.0569.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST000005580981013280_331409.0569.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST00000602682812168_238324.0518.0DomainBromo
TgeneZMYND11chr10:16824033chr10:294276ENST00000602682812280_331324.0518.0DomainPWWP
TgeneZMYND11chr10:16824033chr10:294276ENST000003815911115394_400409.0603.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000003979621115394_400409.0603.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000005095131114394_400408.0568.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000005580981013394_400409.0569.0MotifNuclear localization signal
TgeneZMYND11chr10:16824033chr10:294276ENST000003097761115100_148369.0563.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003815911115100_148409.0603.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003816041115100_148369.0563.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST00000397959913100_148324.0518.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST000003979621115100_148409.0603.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST000005095131114100_148408.0568.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST000005580981013100_148409.0569.0Zinc fingerPHD-type
TgeneZMYND11chr10:16824033chr10:294276ENST00000602682812100_148324.0518.0Zinc fingerPHD-type


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
RSU1
ZMYND11


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to RSU1-ZMYND11


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to RSU1-ZMYND11


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource