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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:SNX6-BAZ1A

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: SNX6-BAZ1A
FusionPDB ID: 85019
FusionGDB2.0 ID: 85019
HgeneTgene
Gene symbol

SNX6

BAZ1A

Gene ID

58533

11177

Gene namesorting nexin 6bromodomain adjacent to zinc finger domain 1A
SynonymsMSTP010|TFAF2ACF1|WALp1|WCRF180|hACF1
Cytomap

14q13.1

14q13.1-q13.2

Type of geneprotein-codingprotein-coding
Descriptionsorting nexin-6TRAF4-associated factor 2tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2bromodomain adjacent to zinc finger domain protein 1AATP-dependent chromatin remodeling proteinATP-utilizing chromatin assembly and remodeling factor 1CHRAC subunit ACF1hWALp1williams syndrome transcription factor-related chromatin-remodeling factor
Modification date2020031320200313
UniProtAcc.

Q9NRL2

Ensembl transtripts involved in fusion geneENST idsENST00000355110, ENST00000362031, 
ENST00000396526, ENST00000396534, 
ENST00000553853, ENST00000358716, 
ENST00000360310, ENST00000382422, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score13 X 10 X 6=7808 X 7 X 5=280
# samples 159
** MAII scorelog2(15/780*10)=-2.37851162325373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/280*10)=-1.63742992061529
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: SNX6 [Title/Abstract] AND BAZ1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)BAZ1A(35107195)-SNX6(35056498), # samples:1
SNX6(35062251)-BAZ1A(35243696), # samples:2
Anticipated loss of major functional domain due to fusion event.SNX6-BAZ1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SNX6-BAZ1A seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSNX6

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

11279102

HgeneSNX6

GO:0045892

negative regulation of transcription, DNA-templated

11279102|20830743

TgeneBAZ1A

GO:0006261

DNA-dependent DNA replication

12434153


check buttonFusion gene breakpoints across SNX6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BAZ1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-6527-01ASNX6chr14

35062251

-BAZ1Achr14

35243696

-
ChimerDB4STADTCGA-D7-6527SNX6chr14

35062250

-BAZ1Achr14

35243696

-


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396526SNX6chr1435062251-ENST00000358716BAZ1Achr1435243696-3482867982704868
ENST00000396526SNX6chr1435062251-ENST00000382422BAZ1Achr1435243696-3481867982704868
ENST00000396526SNX6chr1435062251-ENST00000360310BAZ1Achr1435243696-3476867982704868
ENST00000362031SNX6chr1435062251-ENST00000358716BAZ1Achr1435243696-3400785312622863
ENST00000362031SNX6chr1435062251-ENST00000382422BAZ1Achr1435243696-3399785312622863
ENST00000362031SNX6chr1435062251-ENST00000360310BAZ1Achr1435243696-3394785312622863
ENST00000396526SNX6chr1435062250-ENST00000358716BAZ1Achr1435243696-3482867982704868
ENST00000396526SNX6chr1435062250-ENST00000382422BAZ1Achr1435243696-3481867982704868
ENST00000396526SNX6chr1435062250-ENST00000360310BAZ1Achr1435243696-3476867982704868
ENST00000362031SNX6chr1435062250-ENST00000358716BAZ1Achr1435243696-3400785312622863
ENST00000362031SNX6chr1435062250-ENST00000382422BAZ1Achr1435243696-3399785312622863
ENST00000362031SNX6chr1435062250-ENST00000360310BAZ1Achr1435243696-3394785312622863

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396526ENST00000358716SNX6chr1435062251-BAZ1Achr1435243696-0.0002768320.99972314
ENST00000396526ENST00000382422SNX6chr1435062251-BAZ1Achr1435243696-0.0002777240.9997223
ENST00000396526ENST00000360310SNX6chr1435062251-BAZ1Achr1435243696-0.0002781830.9997218
ENST00000362031ENST00000358716SNX6chr1435062251-BAZ1Achr1435243696-0.0001958180.9998042
ENST00000362031ENST00000382422SNX6chr1435062251-BAZ1Achr1435243696-0.0001972020.99980277
ENST00000362031ENST00000360310SNX6chr1435062251-BAZ1Achr1435243696-0.0001981070.99980193
ENST00000396526ENST00000358716SNX6chr1435062250-BAZ1Achr1435243696-0.0002768320.99972314
ENST00000396526ENST00000382422SNX6chr1435062250-BAZ1Achr1435243696-0.0002777240.9997223
ENST00000396526ENST00000360310SNX6chr1435062250-BAZ1Achr1435243696-0.0002781830.9997218
ENST00000362031ENST00000358716SNX6chr1435062250-BAZ1Achr1435243696-0.0001958180.9998042
ENST00000362031ENST00000382422SNX6chr1435062250-BAZ1Achr1435243696-0.0001972020.99980277
ENST00000362031ENST00000360310SNX6chr1435062250-BAZ1Achr1435243696-0.0001981070.99980193

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>85019_85019_1_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000362031_BAZ1A_chr14_35243696_ENST00000358716_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_2_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000362031_BAZ1A_chr14_35243696_ENST00000360310_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_3_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000362031_BAZ1A_chr14_35243696_ENST00000382422_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_4_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000396526_BAZ1A_chr14_35243696_ENST00000358716_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

>85019_85019_5_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000396526_BAZ1A_chr14_35243696_ENST00000360310_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

>85019_85019_6_SNX6-BAZ1A_SNX6_chr14_35062250_ENST00000396526_BAZ1A_chr14_35243696_ENST00000382422_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

>85019_85019_7_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000362031_BAZ1A_chr14_35243696_ENST00000358716_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_8_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000362031_BAZ1A_chr14_35243696_ENST00000360310_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_9_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000362031_BAZ1A_chr14_35243696_ENST00000382422_length(amino acids)=863AA_BP=252
MRACAGPRLGAAMMEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHD
SFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLE
YNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRGRSSNA
YDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIVKDRLL
GIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDRSVIWS
KSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDE
EEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPP
TETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQS
PEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDIELMFS

--------------------------------------------------------------

>85019_85019_10_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000396526_BAZ1A_chr14_35243696_ENST00000358716_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

>85019_85019_11_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000396526_BAZ1A_chr14_35243696_ENST00000360310_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

>85019_85019_12_SNX6-BAZ1A_SNX6_chr14_35062251_ENST00000396526_BAZ1A_chr14_35243696_ENST00000382422_length(amino acids)=868AA_BP=257
MCLPHLILFPGAPCPPTPQEGLDDGPDFLSEEDRGLKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEEF
IWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNF
HVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKNKPQPDSKPTYSRG
RSSNAYDPSQMCAEKQLELRLRDFLLDIEDRIYQGTLGAIKVTDRHIWRSALESGRYELLSEENKENGIIKTVNEDVEEMEIDEQTKVIV
KDRLLGIKTETPSTVSTNASTPQSVSSVVHYLAMALFQIEQGIERRFLKAPLDASDSGRSYKTVLDRWRESLLSSASLSQVFLHLSTLDR
SVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDE
VDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKI
NSAPPTETKSLRIASRSTRHSHGPLQADVFVELLSPRRKRRGRKSANNTPENSPNFPNFRVIATKSSEQSRSVNIASKLSLQESESKRRC
RKRQSPEPSPVTLGRRSSGRQGGVHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLASEFIDDI

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:35107195/chr14:35056498)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BAZ1A

Q9NRL2

FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S phase. Moves end-positioned nucleosomes to a predominantly central position. May have a role in nuclear receptor-mediated transcription repression.; FUNCTION: Component of the histone-fold protein complex CHRAC complex which facilitates nucleosome sliding by the ACF complex and enhances ACF-mediated chromatin assembly. The C-terminal regions of both CHRAC1 and POLE1 are required for these functions.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-713100_106123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-713114_117123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-71341_47123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-714100_106123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-714114_117123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-71441_47123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-713100_106123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-713114_117123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-71341_47123.33333333333333291.0RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-714100_106123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-714114_117123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-71441_47123.33333333333333755.3333333333334RegionPhosphatidylinositol bisphosphate binding
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000035871616261239_1257912.33333333333341525.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000036031017271239_1257944.33333333333341557.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000038242216261239_1257944.33333333333341557.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000035871616261239_1257912.33333333333341525.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000036031017271239_1257944.33333333333341557.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000038242216261239_1257944.33333333333341557.0Compositional biasNote=Glu-rich
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000035871616261446_1516912.33333333333341525.0DomainBromo
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000036031017271446_1516944.33333333333341557.0DomainBromo
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000038242216261446_1516944.33333333333341557.0DomainBromo
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000035871616261446_1516912.33333333333341525.0DomainBromo
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000036031017271446_1516944.33333333333341557.0DomainBromo
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000038242216261446_1516944.33333333333341557.0DomainBromo
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000035871616261148_1198912.33333333333341525.0Zinc fingerPHD-type
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000036031017271148_1198944.33333333333341557.0Zinc fingerPHD-type
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000038242216261148_1198944.33333333333341557.0Zinc fingerPHD-type
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000035871616261148_1198912.33333333333341525.0Zinc fingerPHD-type
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000036031017271148_1198944.33333333333341557.0Zinc fingerPHD-type
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000038242216261148_1198944.33333333333341557.0Zinc fingerPHD-type

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-713203_406123.33333333333333291.0DomainBAR
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-71326_173123.33333333333333291.0DomainPX
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-714203_406123.33333333333333755.3333333333334DomainBAR
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-71426_173123.33333333333333755.3333333333334DomainPX
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-713203_406123.33333333333333291.0DomainBAR
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-71326_173123.33333333333333291.0DomainPX
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-714203_406123.33333333333333755.3333333333334DomainBAR
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-71426_173123.33333333333333755.3333333333334DomainPX
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-713182_199123.33333333333333291.0RegionMembrane-binding amphipathic helix
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-714182_199123.33333333333333755.3333333333334RegionMembrane-binding amphipathic helix
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-713182_199123.33333333333333291.0RegionMembrane-binding amphipathic helix
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-714182_199123.33333333333333755.3333333333334RegionMembrane-binding amphipathic helix
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003587161626306_397912.33333333333341525.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003587161626634_709912.33333333333341525.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003603101727306_397944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003603101727634_709944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003824221626306_397944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003824221626634_709944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003587161626306_397912.33333333333341525.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003587161626634_709912.33333333333341525.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003603101727306_397944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003603101727634_709944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003824221626306_397944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003824221626634_709944.33333333333341557.0Coiled coilOntology_term=ECO:0000255
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003587161626487_491912.33333333333341525.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003603101727487_491944.33333333333341557.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003824221626487_491944.33333333333341557.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003587161626487_491912.33333333333341525.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003603101727487_491944.33333333333341557.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003824221626487_491944.33333333333341557.0Compositional biasNote=Poly-Glu
TgeneBAZ1Achr14:35062250chr14:35243696ENST00000358716162622_128912.33333333333341525.0DomainWAC
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003587161626422_487912.33333333333341525.0DomainDDT
TgeneBAZ1Achr14:35062250chr14:35243696ENST00000360310172722_128944.33333333333341557.0DomainWAC
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003603101727422_487944.33333333333341557.0DomainDDT
TgeneBAZ1Achr14:35062250chr14:35243696ENST00000382422162622_128944.33333333333341557.0DomainWAC
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003824221626422_487944.33333333333341557.0DomainDDT
TgeneBAZ1Achr14:35062251chr14:35243696ENST00000358716162622_128912.33333333333341525.0DomainWAC
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003587161626422_487912.33333333333341525.0DomainDDT
TgeneBAZ1Achr14:35062251chr14:35243696ENST00000360310172722_128944.33333333333341557.0DomainWAC
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003603101727422_487944.33333333333341557.0DomainDDT
TgeneBAZ1Achr14:35062251chr14:35243696ENST00000382422162622_128944.33333333333341557.0DomainWAC
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003824221626422_487944.33333333333341557.0DomainDDT
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000035871616261_128912.33333333333341525.0RegionNote=Required for association with the CHRAC1/POLE3 complex
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000036031017271_128944.33333333333341557.0RegionNote=Required for association with the CHRAC1/POLE3 complex
TgeneBAZ1Achr14:35062250chr14:35243696ENST0000038242216261_128944.33333333333341557.0RegionNote=Required for association with the CHRAC1/POLE3 complex
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000035871616261_128912.33333333333341525.0RegionNote=Required for association with the CHRAC1/POLE3 complex
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000036031017271_128944.33333333333341557.0RegionNote=Required for association with the CHRAC1/POLE3 complex
TgeneBAZ1Achr14:35062251chr14:35243696ENST0000038242216261_128944.33333333333341557.0RegionNote=Required for association with the CHRAC1/POLE3 complex


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
SNX6
BAZ1A


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSNX6chr14:35062250chr14:35243696ENST00000396526-7132_179123.33333333333333291.0PIM1
HgeneSNX6chr14:35062250chr14:35243696ENST00000396534-7142_179123.33333333333333755.3333333333334PIM1
HgeneSNX6chr14:35062251chr14:35243696ENST00000396526-7132_179123.33333333333333291.0PIM1
HgeneSNX6chr14:35062251chr14:35243696ENST00000396534-7142_179123.33333333333333755.3333333333334PIM1
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003587161626667_933912.33333333333341525.0SMARCA5
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003603101727667_933944.33333333333341557.0SMARCA5
TgeneBAZ1Achr14:35062250chr14:35243696ENST000003824221626667_933944.33333333333341557.0SMARCA5
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003587161626667_933912.33333333333341525.0SMARCA5
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003603101727667_933944.33333333333341557.0SMARCA5
TgeneBAZ1Achr14:35062251chr14:35243696ENST000003824221626667_933944.33333333333341557.0SMARCA5


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Related Drugs to SNX6-BAZ1A


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to SNX6-BAZ1A


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource