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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:SSBP2-NTRK1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: SSBP2-NTRK1
	FusionPDB ID: 86715
	FusionGDB2.0 ID: 86715
		Hgene	Tgene
	Gene symbol	SSBP2	NTRK1
	Gene ID	23635	4914
	Gene name	single stranded DNA binding protein 2	neurotrophic receptor tyrosine kinase 1
	Synonyms	HSPC116\|SOSS-B2	MTC\|TRK\|TRK1\|TRKA\|Trk-A\|p140-TrkA
	Cytomap	5q14.1	1q23.1
	Type of gene	protein-coding	protein-coding
	Description	single-stranded DNA-binding protein 2sequence-specific single-stranded-DNA-binding protein 2	high affinity nerve growth factor receptorOncogene TRKTRK1-transforming tyrosine kinase proteingp140trkneurotrophic tyrosine kinase, receptor, type 1tropomyosin-related kinase Atyrosine kinase receptor A
	Modification date	20200313	20200313
	UniProtAcc	P81877	P04629
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000320672, ENST00000505980, ENST00000509053, ENST00000514493, ENST00000515395, ENST00000510060,	ENST00000531606, ENST00000358660, ENST00000368196, ENST00000392302, ENST00000524377,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	12 X 13 X 6=936	25 X 24 X 13=7800
	# samples	14	33
	** MAII score	log2(14/936*10)=-2.74108170263844 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(33/7800*10)=-4.56293619439116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: SSBP2 [Title/Abstract] AND NTRK1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	SSBP2(80742687)-NTRK1(156845312), # samples:3
Anticipated loss of major functional domain due to fusion event.	SSBP2-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. SSBP2-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. SSBP2-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. SSBP2-NTRK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	NTRK1	GO:0006468	protein phosphorylation	15488758
Tgene	NTRK1	GO:0008285	negative regulation of cell proliferation	15488758
Tgene	NTRK1	GO:0010976	positive regulation of neuron projection development	15488758
Tgene	NTRK1	GO:0018108	peptidyl-tyrosine phosphorylation	2927393
Tgene	NTRK1	GO:0043547	positive regulation of GTPase activity	15488758
Tgene	NTRK1	GO:0046579	positive regulation of Ras protein signal transduction	15488758
Tgene	NTRK1	GO:0046777	protein autophosphorylation	15488758
Tgene	NTRK1	GO:0048011	neurotrophin TRK receptor signaling pathway	15488758
Tgene	NTRK1	GO:0051092	positive regulation of NF-kappaB transcription factor activity	15488758
Tgene	NTRK1	GO:0070374	positive regulation of ERK1 and ERK2 cascade	15488758
Tgene	NTRK1	GO:1904646	cellular response to amyloid-beta	11927634

Fusion gene breakpoints across SSBP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across NTRK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	THCA	TCGA-CE-A3MD-01A	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+
ChimerDB4	THCA	TCGA-CE-A3MD	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000320672	SSBP2	chr5	80742687	-	ENST00000392302	NTRK1	chr1	156845312	+	2178	989	211	2025	604
ENST00000320672	SSBP2	chr5	80742687	-	ENST00000368196	NTRK1	chr1	156845312	+	2234	989	211	2025	604
ENST00000320672	SSBP2	chr5	80742687	-	ENST00000524377	NTRK1	chr1	156845312	+	2026	989	211	2025	605
ENST00000320672	SSBP2	chr5	80742687	-	ENST00000358660	NTRK1	chr1	156845312	+	2104	989	211	2034	607
ENST00000509053	SSBP2	chr5	80742687	-	ENST00000392302	NTRK1	chr1	156845312	+	1883	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742687	-	ENST00000368196	NTRK1	chr1	156845312	+	1939	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742687	-	ENST00000524377	NTRK1	chr1	156845312	+	1731	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742687	-	ENST00000358660	NTRK1	chr1	156845312	+	1809	694	6	1739	577
ENST00000514493	SSBP2	chr5	80742687	-	ENST00000392302	NTRK1	chr1	156845312	+	2085	896	208	1932	574
ENST00000514493	SSBP2	chr5	80742687	-	ENST00000368196	NTRK1	chr1	156845312	+	2141	896	208	1932	574
ENST00000514493	SSBP2	chr5	80742687	-	ENST00000524377	NTRK1	chr1	156845312	+	1933	896	208	1932	575
ENST00000514493	SSBP2	chr5	80742687	-	ENST00000358660	NTRK1	chr1	156845312	+	2011	896	208	1941	577
ENST00000505980	SSBP2	chr5	80742687	-	ENST00000392302	NTRK1	chr1	156845312	+	1912	723	5	1759	584
ENST00000505980	SSBP2	chr5	80742687	-	ENST00000368196	NTRK1	chr1	156845312	+	1968	723	5	1759	584
ENST00000505980	SSBP2	chr5	80742687	-	ENST00000524377	NTRK1	chr1	156845312	+	1760	723	5	1759	585
ENST00000505980	SSBP2	chr5	80742687	-	ENST00000358660	NTRK1	chr1	156845312	+	1838	723	5	1768	587
ENST00000515395	SSBP2	chr5	80742687	-	ENST00000392302	NTRK1	chr1	156845312	+	1956	767	55	1803	582
ENST00000515395	SSBP2	chr5	80742687	-	ENST00000368196	NTRK1	chr1	156845312	+	2012	767	55	1803	582
ENST00000515395	SSBP2	chr5	80742687	-	ENST00000524377	NTRK1	chr1	156845312	+	1804	767	55	1803	583
ENST00000515395	SSBP2	chr5	80742687	-	ENST00000358660	NTRK1	chr1	156845312	+	1882	767	55	1812	585
ENST00000320672	SSBP2	chr5	80742686	-	ENST00000392302	NTRK1	chr1	156845311	+	2178	989	211	2025	604
ENST00000320672	SSBP2	chr5	80742686	-	ENST00000368196	NTRK1	chr1	156845311	+	2234	989	211	2025	604
ENST00000320672	SSBP2	chr5	80742686	-	ENST00000524377	NTRK1	chr1	156845311	+	2026	989	211	2025	605
ENST00000320672	SSBP2	chr5	80742686	-	ENST00000358660	NTRK1	chr1	156845311	+	2104	989	211	2034	607
ENST00000509053	SSBP2	chr5	80742686	-	ENST00000392302	NTRK1	chr1	156845311	+	1883	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742686	-	ENST00000368196	NTRK1	chr1	156845311	+	1939	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742686	-	ENST00000524377	NTRK1	chr1	156845311	+	1731	694	6	1730	574
ENST00000509053	SSBP2	chr5	80742686	-	ENST00000358660	NTRK1	chr1	156845311	+	1809	694	6	1739	577
ENST00000514493	SSBP2	chr5	80742686	-	ENST00000392302	NTRK1	chr1	156845311	+	2085	896	208	1932	574
ENST00000514493	SSBP2	chr5	80742686	-	ENST00000368196	NTRK1	chr1	156845311	+	2141	896	208	1932	574
ENST00000514493	SSBP2	chr5	80742686	-	ENST00000524377	NTRK1	chr1	156845311	+	1933	896	208	1932	575
ENST00000514493	SSBP2	chr5	80742686	-	ENST00000358660	NTRK1	chr1	156845311	+	2011	896	208	1941	577
ENST00000505980	SSBP2	chr5	80742686	-	ENST00000392302	NTRK1	chr1	156845311	+	1912	723	5	1759	584
ENST00000505980	SSBP2	chr5	80742686	-	ENST00000368196	NTRK1	chr1	156845311	+	1968	723	5	1759	584
ENST00000505980	SSBP2	chr5	80742686	-	ENST00000524377	NTRK1	chr1	156845311	+	1760	723	5	1759	585
ENST00000505980	SSBP2	chr5	80742686	-	ENST00000358660	NTRK1	chr1	156845311	+	1838	723	5	1768	587
ENST00000515395	SSBP2	chr5	80742686	-	ENST00000392302	NTRK1	chr1	156845311	+	1956	767	55	1803	582
ENST00000515395	SSBP2	chr5	80742686	-	ENST00000368196	NTRK1	chr1	156845311	+	2012	767	55	1803	582
ENST00000515395	SSBP2	chr5	80742686	-	ENST00000524377	NTRK1	chr1	156845311	+	1804	767	55	1803	583
ENST00000515395	SSBP2	chr5	80742686	-	ENST00000358660	NTRK1	chr1	156845311	+	1882	767	55	1812	585

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000320672	ENST00000392302	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.04760339	0.9523966
ENST00000320672	ENST00000368196	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.044757053	0.95524293
ENST00000320672	ENST00000524377	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.044645447	0.9553545
ENST00000320672	ENST00000358660	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.04593243	0.9540676
ENST00000509053	ENST00000392302	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.057340503	0.9426595
ENST00000509053	ENST00000368196	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.052673448	0.94732654
ENST00000509053	ENST00000524377	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.046852514	0.9531475
ENST00000509053	ENST00000358660	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.051347658	0.9486523
ENST00000514493	ENST00000392302	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.058813892	0.9411861
ENST00000514493	ENST00000368196	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.056621727	0.94337827
ENST00000514493	ENST00000524377	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.05817458	0.9418254
ENST00000514493	ENST00000358660	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.06267552	0.93732446
ENST00000505980	ENST00000392302	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.037561335	0.9624387
ENST00000505980	ENST00000368196	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.034396965	0.96560305
ENST00000505980	ENST00000524377	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.030253552	0.9697464
ENST00000505980	ENST00000358660	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.03076716	0.9692329
ENST00000515395	ENST00000392302	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.051890854	0.94810915
ENST00000515395	ENST00000368196	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.04856797	0.95143205
ENST00000515395	ENST00000524377	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.047721628	0.9522784
ENST00000515395	ENST00000358660	SSBP2	chr5	80742687	-	NTRK1	chr1	156845312	+	0.052175865	0.9478242
ENST00000320672	ENST00000392302	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.04760339	0.9523966
ENST00000320672	ENST00000368196	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.044757053	0.95524293
ENST00000320672	ENST00000524377	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.044645447	0.9553545
ENST00000320672	ENST00000358660	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.04593243	0.9540676
ENST00000509053	ENST00000392302	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.057340503	0.9426595
ENST00000509053	ENST00000368196	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.052673448	0.94732654
ENST00000509053	ENST00000524377	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.046852514	0.9531475
ENST00000509053	ENST00000358660	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.051347658	0.9486523
ENST00000514493	ENST00000392302	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.058813892	0.9411861
ENST00000514493	ENST00000368196	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.056621727	0.94337827
ENST00000514493	ENST00000524377	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.05817458	0.9418254
ENST00000514493	ENST00000358660	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.06267552	0.93732446
ENST00000505980	ENST00000392302	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.037561335	0.9624387
ENST00000505980	ENST00000368196	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.034396965	0.96560305
ENST00000505980	ENST00000524377	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.030253552	0.9697464
ENST00000505980	ENST00000358660	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.03076716	0.9692329
ENST00000515395	ENST00000392302	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.051890854	0.94810915
ENST00000515395	ENST00000368196	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.04856797	0.95143205
ENST00000515395	ENST00000524377	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.047721628	0.9522784
ENST00000515395	ENST00000358660	SSBP2	chr5	80742686	-	NTRK1	chr1	156845311	+	0.052175865	0.9478242

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>86715_86715_1_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000320672_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=607AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>86715_86715_2_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000320672_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=604AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_3_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000320672_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=604AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_4_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000320672_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=605AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_5_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000505980_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=587AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQH
QHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVG
QGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERP

--------------------------------------------------------------

>86715_86715_6_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000505980_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=584AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_7_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000505980_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=584AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_8_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000505980_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=585AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_9_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000509053_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=577AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVC
TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDF
GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAI

--------------------------------------------------------------

>86715_86715_10_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000509053_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_11_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000509053_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_12_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000509053_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_13_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000514493_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=577AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVC
TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDF
GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAI

--------------------------------------------------------------

>86715_86715_14_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000514493_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_15_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000514493_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_16_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000514493_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=575AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_17_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000515395_NTRK1_chr1_156845311_ENST00000358660_length(amino acids)=585AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQH
IVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQG
LVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRA

--------------------------------------------------------------

>86715_86715_18_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000515395_NTRK1_chr1_156845311_ENST00000368196_length(amino acids)=582AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>86715_86715_19_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000515395_NTRK1_chr1_156845311_ENST00000392302_length(amino acids)=582AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>86715_86715_20_SSBP2-NTRK1_SSBP2_chr5_80742686_ENST00000515395_NTRK1_chr1_156845311_ENST00000524377_length(amino acids)=583AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>86715_86715_21_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000320672_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=607AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA
SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV
YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY

--------------------------------------------------------------

>86715_86715_22_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000320672_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=604AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_23_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000320672_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=604AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_24_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000320672_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=605AA_BP=259
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTP
PRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGL
AMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES
ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA
GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS

--------------------------------------------------------------

>86715_86715_25_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000505980_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=587AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQH
QHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVG
QGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERP

--------------------------------------------------------------

>86715_86715_26_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000505980_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=584AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_27_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000505980_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=584AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_28_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000505980_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=585AA_BP=239
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYSAAAAPSPVLGNIPPGDGMPVGPVPPGFFQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPL
NALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGK
GSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHI
VRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGL
VVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRAC

--------------------------------------------------------------

>86715_86715_29_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000509053_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=577AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVC
TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDF
GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAI

--------------------------------------------------------------

>86715_86715_30_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000509053_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_31_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000509053_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_32_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000509053_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_33_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000514493_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=577AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVC
TEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDF
GMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAI

--------------------------------------------------------------

>86715_86715_34_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000514493_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_35_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000514493_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=574AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_36_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000514493_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=575AA_BP=229
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPG
MNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIE
NPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEG
RPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMS
RDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRG

--------------------------------------------------------------

>86715_86715_37_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000515395_NTRK1_chr1_156845312_ENST00000358660_length(amino acids)=585AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQH
IVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQG
LVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRA

--------------------------------------------------------------

>86715_86715_38_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000515395_NTRK1_chr1_156845312_ENST00000368196_length(amino acids)=582AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>86715_86715_39_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000515395_NTRK1_chr1_156845312_ENST00000392302_length(amino acids)=582AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

>86715_86715_40_SSBP2-NTRK1_SSBP2_chr5_80742687_ENST00000515395_NTRK1_chr1_156845312_ENST00000524377_length(amino acids)=583AA_BP=237
MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKA
FHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQSDPWLSLQNYGGAMRPPLNA
LGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPAGPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGS
GLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVR
FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVV
KIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPP

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:80742687/chr1:156845312)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
SSBP2 P81877	NTRK1 P04629
	FUNCTION: Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand (PubMed:1850821, PubMed:1849459, PubMed:1281417, PubMed:8325889, PubMed:15488758, PubMed:22649032, PubMed:17196528, PubMed:27445338). Can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival (By similarity). Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation (PubMed:1281417). Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. {ECO:0000250\|UniProtKB:P35739, ECO:0000250\|UniProtKB:Q3UFB7, ECO:0000269\|PubMed:11244088, ECO:0000269\|PubMed:1281417, ECO:0000269\|PubMed:15488758, ECO:0000269\|PubMed:17196528, ECO:0000269\|PubMed:1849459, ECO:0000269\|PubMed:1850821, ECO:0000269\|PubMed:22649032, ECO:0000269\|PubMed:27445338, ECO:0000269\|PubMed:27676246, ECO:0000269\|PubMed:8155326, ECO:0000269\|PubMed:8325889}.; FUNCTION: [Isoform TrkA-III]: Resistant to NGF, it constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed. {ECO:0000269\|PubMed:15488758}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000320672

18_50

259.3333333333333

362.0

Domain

LisH

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000505980

18_50

239.33333333333334

342.0

Domain

LisH

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000509053

18_50

229.33333333333334

299.0

Domain

LisH

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000514493

18_50

229.33333333333334

332.0

Domain

LisH

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000515395

18_50

237.33333333333334

340.0

Domain

LisH

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000320672

18_50

259.3333333333333

362.0

Domain

LisH

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000505980

18_50

239.33333333333334

342.0

Domain

LisH

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000509053

18_50

229.33333333333334

299.0

Domain

LisH

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000514493

18_50

229.33333333333334

332.0

Domain

LisH

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000515395

18_50

237.33333333333334

340.0

Domain

LisH

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

510_781

445.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

510_781

415.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

510_781

451.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

510_781

445.3333333333333

791.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

510_781

415.3333333333333

761.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

510_781

451.3333333333333

797.0

Domain

Protein kinase

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

537_541

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

607_611

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

537_541

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

607_611

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

537_541

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

607_611

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

537_541

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

607_611

445.3333333333333

791.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

537_541

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

607_611

415.3333333333333

761.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

537_541

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

607_611

451.3333333333333

797.0

Motif

DXXLL

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

516_524

445.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

516_524

415.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

516_524

451.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

516_524

445.3333333333333

791.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

516_524

415.3333333333333

761.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

516_524

451.3333333333333

797.0

Nucleotide binding

ATP

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

440_796

415.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

440_796

415.3333333333333

761.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

424_439

415.3333333333333

761.0

Transmembrane

Helical

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

424_439

415.3333333333333

761.0

Transmembrane

Helical

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000320672

100_293

259.3333333333333

362.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000320672

147_312

259.3333333333333

362.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000505980

100_293

239.33333333333334

342.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000505980

147_312

239.33333333333334

342.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000509053

100_293

229.33333333333334

299.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000509053

147_312

229.33333333333334

299.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000514493

100_293

229.33333333333334

332.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000514493

147_312

229.33333333333334

332.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000515395

100_293

237.33333333333334

340.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742686

chr1:156845311

ENST00000515395

147_312

237.33333333333334

340.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000320672

100_293

259.3333333333333

362.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000320672

147_312

259.3333333333333

362.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000505980

100_293

239.33333333333334

342.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000505980

147_312

239.33333333333334

342.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000509053

100_293

229.33333333333334

299.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000509053

147_312

229.33333333333334

299.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000514493

100_293

229.33333333333334

332.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000514493

147_312

229.33333333333334

332.0

Compositional bias

Note=Gly-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000515395

100_293

237.33333333333334

340.0

Compositional bias

Note=Pro-rich

Hgene

SSBP2

chr5:80742687

chr1:156845312

ENST00000515395

147_312

237.33333333333334

340.0

Compositional bias

Note=Gly-rich

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

148_193

445.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

194_283

445.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

299_365

445.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

148_193

415.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

194_283

415.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

299_365

415.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

148_193

451.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

194_283

451.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

299_365

451.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

148_193

445.3333333333333

791.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

194_283

445.3333333333333

791.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

299_365

445.3333333333333

791.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

148_193

415.3333333333333

761.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

194_283

415.3333333333333

761.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

299_365

415.3333333333333

761.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

148_193

451.3333333333333

797.0

Domain

Note=LRRCT

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

194_283

451.3333333333333

797.0

Domain

Ig-like C2-type 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

299_365

451.3333333333333

797.0

Domain

Ig-like C2-type 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

116_137

445.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

90_113

445.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

116_137

415.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

90_113

415.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

116_137

451.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

90_113

451.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

116_137

445.3333333333333

791.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

90_113

445.3333333333333

791.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

116_137

415.3333333333333

761.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

90_113

415.3333333333333

761.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

116_137

451.3333333333333

797.0

Repeat

Note=LRR 2

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

90_113

451.3333333333333

797.0

Repeat

Note=LRR 1

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

33_423

445.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

440_796

445.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000392302

33_423

415.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

33_423

451.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

440_796

451.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

33_423

445.3333333333333

791.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

440_796

445.3333333333333

791.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000392302

33_423

415.3333333333333

761.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

33_423

451.3333333333333

797.0

Topological domain

Extracellular

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

440_796

451.3333333333333

797.0

Topological domain

Cytoplasmic

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000368196

424_439

445.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr5:80742686

chr1:156845311

ENST00000524377

424_439

451.3333333333333

797.0

Transmembrane

Helical

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000368196

424_439

445.3333333333333

791.0

Transmembrane

Helical

Tgene

NTRK1

chr5:80742687

chr1:156845312

ENST00000524377

424_439

451.3333333333333

797.0

Transmembrane

Helical

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene	PPI interactors
NTRK1	ABL1, NGF, MATK, PLCG1, GRB2, CAV1, NTF3, SQSTM1, SH2B1, SHC1, SH2B2, ARHGAP32, FRS2, NTRK1, RAP1A, SHC3, GIPC1, RGS19, PTPN1, TRAF6, NEDD4, CBL, HSP90AA1, HSPA4, CDC37, NEDD4L, MYC, SGSM3, SORBS1, TNK2, SNX17, SNX27, GAREML, SOS2, PIK3CA, GAREM, PIK3C2B, ARHGEF40, PIK3R1, PIK3R2, SOS1, PIK3CB, PML, UBC, AMFR, CBLB, GAB1, EPN1, PIK3C2A, ANKRD13A, DOCK4, TRIO, LGR5, WRNIP1, RABEP1, PDGFRA, KANK2, RABGEF1, VAV2, TBC1D15, PTPN11, GAK, IRS2, PCDHGC3, EPS15, LRRN3, HUWE1, ACVR1B, MIB1, OFD1, PIBF1, ZNF497, TXN, CAT, FABP3, JUP, DSG1, TGM1, CFL1, LCN1, HIST2H4A, DSP, PFN1, LGALS3BP, HIST1H2BL, LTF, S100A9, IGLL5, TGM3, DSC1, LYZ, DCD, LEKR1, ENO2, PPIA, BTN1A1, XRCC5, XRCC6, HLA-A, GSTP1, ABCB7, PA2G4, PRDX1, HDGF, HSPA4L, TBC1D10B, HP1BP3, KIF26B, SYT4, RHOBTB3, NOTCH3, GAB2, ATAD3A, RBM15B, KCNH2, USP15, PDCD11, RBFOX2, RBM14, RNF31, ADNP, ZC3HAV1, MAP7D1, USP4, JAK1, PTPRS, PDGFRB, HIST1H1C, USP11, PPFIBP1, INTS6, VGF, ARHGEF11, SMPD4, SYNPO2, HNRNPM, SLC27A4, DDX41, EGFR, H1FX, ASAP1, HIST1H1B, RRBP1, EPHA2, KIDINS220, CPT1A, UNC5B, IGF1R, DDR2, AUP1, XPR1, RP9, MARK2, REPS1, EMD, SMARCA4, DDX21, DAB2IP, C7, MSTO1, CDC27, ZNF629, ASAP2, NCAPH2, SRBD1, ATAD3B, TCF12, PLEKHA6, INPPL1, PRPF4B, DPM1, SMARCA1, FIP1L1, DLGAP5, PLEKHH3, TRA2A, ACIN1, DDX10, TAX1BP1, SMARCA5, RABEP2, DDX5, MYO1C, SRSF10, DNAJA2, RET, TRA2B, MYEF2, PNPLA6, SLC12A2, TAF6L, RSL1D1, ARAP3, DDX18, ABL2, KHDRBS1, CERK, SRSF7, SPTLC2, PBXIP1, DNAJA1, IQGAP3, DDX31, ZC3H11A, PLRG1, CNP, FMR1, HIP1R, KIAA1429, CDC5L, ARAP1, ZNF316, SMARCC2, EML5, VANGL2, SLC25A1, UNC5C, SLC16A1, RFC1, ZKSCAN1, CHD1, PTK7, SMARCD2, AP3B1, YTHDC2, AKAP8L, RPL15, CTNND1, PHLDB1, ZNF574, DDX27, TOM1, RASA1, MORC2, MTCH2, IMMT, SMARCC1, ROR2, CAPN2, DNAJC11, SYT11, AP2A1, LBR, MEPCE, NCAPD3, CEP97, QKI, LRRC41, LPCAT2, EPS15L1, LAS1L, TMEM131, CWF19L2, NCAPG2, MAP4K5, CCP110, ARHGEF2, ITGAV, ZC3H18, CWC22, VIM, FAM171A1, TMEM132A, SRSF9, SOGA1, NKRF, RBL1, FMNL3, TOP1, PIGT, RBM15, GBAS, EDC3, WDR5, NOP2, GNL2, SLC25A11, RRP1B, FAM115A, INTS5, SLC25A5, AAK1, HERC5, CCNT1, FERMT2, CDC42BPA, MRPL28, UBAP2, WWP2, SEC24B, HNRNPU, GPD2, FXR2, DHX15, SLC25A22, SSR1, PLXNB2, PROX1, TEX10, USP19, FTSJ3, TMEM59, GTF3C2, PGAM5, CPSF1, KLHL22, TMX3, SIN3A, NOP58, PTCD3, RPRD2, DHX9, PICALM, FARP1, SLC25A6, ERLIN2, SMARCD1, RHOT1, ALDH1B1, SGPL1, USP9X, HNRNPF, KIAA1211, MAPK7, DDX17, GSE1, DVL3, MRPL44, DNAJB6, GTPBP4, HNRNPA0, PLXNA4, SFXN3, NAT10, DDX28, SNW1, MYO6, MRPL24, PRRT4, FAM98A, PURA, DHX29, C1QBP, TRIP4, TBK1, RBM28, ZNF609, POLRMT, PCDHB3, XRN1, HSD17B11, DKC1, DHX30, CDK13, SENP3, LPHN2, GPATCH4, NDUFA9, RASA4, MCCC1, DDX24, RPL14, RPS8, ATG2B, MYO1B, PTPN12, CEBPZ, ILVBL, RALY, KIF14, ZC3H7A, MOV10, MAP4K4, DHX57, RBMX, FXR1, MRPS35, SART1, MARK3, DECR1, CCDC88A, ANKLE2, PRPF31, LARP7, RPL10, PACS1, RPL13, FAM120A, SLC25A13, ADAR, CDK1, HNRNPR, CSNK1E, DLG1, LEMD3, NOL9, IFT122, NCLN, STK11IP, GATAD2B, CHERP, LARP4, MAP3K1, HNRNPUL2, PPIL2, ESYT2, MYH10, RPL8, UQCRC2, NDUFA10, HAX1, HELLS, MED14, RBM42, CHCHD3, RPL7, ABCD3, TUBGCP6, MRPS9, SNRNP200, IGF2BP3, LRCH3, MRPL3, RSBN1L, SAFB, TUBG1, ALDH16A1, ARHGEF12, EPB41L5, AP2A2, SRSF6, HLTF, PTPLAD1, TMPO, AGO2, POP1, RPS9, HDAC6, ILF3, VWA8, ABCB1, SCRIB, GTF3C5, YBX1, RBM4, PTPN9, PRPF8, BRD3, TRIM24, CLASP2, MADD, TCF4, MAP4K3, TSC2, DDX23, RPL7A, RRP12, PRKD2, TRMT1L, EDC4, CSTF3, RPS2, NDUFS2, RPL13A, PTPRR, ATP7A, EXD2, IK, HIP1, MATR3, IGSF3, PTPRF, SPATA5L1, EFTUD2, RPS3A, TUBGCP5, TTN, GIT1, PATL1, NUP160, PDE4B, SUN2, PTPN23, RPS6, DCP1A, CDC73, MEX3A, EIF2AK2, RPL3, PPP1R10, SRP72, ELAVL3, NOM1, RPL18, CEP170, THRAP3, MED17, MRPS7, DDX20, PDPR, SH3PXD2A, DBN1, DAP3, OAS3, STT3B, COPE, MED12, AP3D1, CAPRIN1, PHB2, U2SURP, BSG, TECR, FARSA, HSD17B12, RPL4, HNRNPUL1, PPFIA1, MRPS22, TBL3, GNL3, MTA2, CPSF2, ATP2B1, AP3B2, PPIP5K2, DDX56, ASCC3, FMNL2, SMCHD1, MYBBP1A, SRPK2, RHOT2, SRP68, PUM1, SLC25A3, SRPK1, RPL19, BEND3, SEC61A1, LSG1, NOC3L, TNKS1BP1, GTF3C3, TUBGCP3, PRPF40A, TRMT10C, URGCP, XRN2, MSH3, XRCC1, GEMIN4, DIS3L2, BCLAF1, SBF2, DHTKD1, ATXN2, ARID4B, TOR1AIP1, RPL29, NAA16, PRPF6, KIFAP3, TMEM33, WASF2, NACAD, LIG3, POLE, CKAP4, TCEB3, MTA1, GNA13, DHX38, PHF6, ELAVL4, DDX3X, CTR9, PRPF19, CAMSAP2, PRMT3, SH3PXD2B, SCAF8, MAGED1, ILF2, TONSL, PPP1R12A, SRSF5, KIAA0020, PTBP1, CAD, ACSL3, CHD1L, STAU1, MRPL38, DVL2, GNAI3, RPL10A, RPL6, MRPS5, CDK11B, MRPS34, PES1, ATP5C1, STXBP3, HNRNPLL, CHTF18, VPS39, SART3, COPA, PRPF3, UBE2O, ABCF2, HNRNPH3, EARS2, DHX40, ARHGEF7, EMC1, CASK, PTK2, SORT1, OGT, ATP12A, LMNB1, SLC4A7, PFKP, VDAC2, RBM25, ATL3, DHX36, TFIP11, EXOSC10, GTF3C1, SRSF1, PPP6C, TRAPPC9, RAD21, DNAJC13, ACOT1, ZC3H4, SRRM1, NDUFS3, DYRK1A, INTS1, SF3B2, EHHADH, MYO9B, ASCC2, WDR11, RPN1, EHD4, WDR91, SMARCAL1, NBAS, PI4KA, PAF1, EIF2B4, NUP107, EMC2, SYNE1, KLHL13, TBL1XR1, DNAJC10, SEC16A, METTL13, C7orf50, CDC42BPB, CLCN5, PGM3, DOCK7, ALYREF, POLR3A, TOP3A, WDR48, WDR81, DOCK1, CSNK2A2, CYC1, TLE3, THOC2, EIF2S3, MYO5A, SNX9, TARDBP, NAP1L4, CRKL, YTHDF2, PYGB, PABPC1, LTV1, PSMD4, KTN1, UBTF, WDR6, FUBP3, UBXN7, PHB, PDXP, CNOT3, TBL2, LLGL1, PLOD1, AHSA1, AAAS, ERGIC1, LARP4B, CYFIP1, DNM1, TARS2, ACSL1, ATXN1L, WDR59, SUCLA2, MLH1, CSNK2B, SYNCRIP, WDR36, FAM91A1, MTDH, UBE3C, CAPN1, BRIX1, DNAJB11, EDEM3, PLOD3, CLASP1, DPYSL3, MED16, NONO, EPM2AIP1, NT5DC2, ADRBK2, RPTOR, TELO2, MRPL37, PRKACB, ELMO1, TRAPPC8, ANAPC1, NIPSNAP1, EWSR1, PIK3R4, POLD1, IQGAP1, PRRC2A, COG1, ANKRD44, TFRC, DIEXF, FHOD1, SERPINH1, SPATA5, MED1, ABCF3, ZSWIM8, LMNA, HAT1, PABPC4, SMC4, HADH, RNGTT, TUBGCP2, ZNF598, SKIV2L2, GNB2L1, LARP1, DIP2B, BCR, IDH3B, LSM14A, FBL, NDUFS1, APPL2, USP39, SMC2, HCFC1, LANCL1, POLR2B, UPF2, CCBL2, MRPL15, MAGED2, AGK, GNPAT, AIMP1, GTF3C4, KDM1A, SCAMP3, RDH11, SRGAP2, CRNKL1, RFC5, PFKL, SPTBN1, PHOX2A, VDAC3, HNRNPA1, WDR26, DNM2, HAUS5, LCMT2, MCM7, CLINT1, UGDH, ACO1, TRIM46, PHKB, USP10, PCF11, YTHDF3, AARS2, FIGNL1, SFPQ, ATP5A1, NUP133, CPSF3, ANKRD28, PNN, C9orf64, ABCF1, ATL1, NAP1L1, HSPA9, MCCC2, FKBP5, CNOT1, TAF6, NEMF, UHRF1, SDHA, PELP1, HADHB, OAT, NEK9, AP3M1, PRKCA, LPCAT1, MRPL39, AFG3L2, WASF1, HNRNPL, RALGAPB, HK1, GBA, PLD3, CPSF7, HADHA, PDE12, DCX, LIMA1, HNRNPA2B1, POLR2A, MYH9, ZNF207, DDX55, ELP3, EIF2B5, MICAL1, TTI1, NES, HSDL1, GPSM1, PPM1F, C4orf27, SRRM2, OSBPL9, STAT3, IRF2BPL, KLC2, P3H1, STAT5B, UQCRC1, PCK2, CCAR2, TBC1D5, SACM1L, QARS, XPO4, CHD4, KIF2A, TACC3, NCL, BTAF1, RARS2, NCKAP1, EIF3D, RPS3, YME1L1, EIF4A3, HAUS6, HNRNPDL, MON2, G3BP2, WDHD1, CSNK1A1, SDAD1, RPS25, LSM14B, AP1M1, CCDC47, HNRNPK, DNMT1, NUP85, CUL5, TANC1, STAT1, COG5, STOML2, CDC45, OSBPL11, CIC, ABCD2, ARFGEF1, TROVE2, GBF1, SRPRB, UBE3A, GTPBP1, SCCPDH, RPS4X, PRPF4, ACTL6A, CCAR1, KIAA1033, TRAPPC12, HNRNPA3, FASTKD5, LYN, VPS18, PGRMC2, NUP214, AIFM1, TSG101, PPP6R3, OCRL, GANAB, IARS, SARS2, ATP2A2, EXOC1, NCAPH, TTC27, GNE, SRC, MIOS, ZCCHC8, GOLGA2, CARM1, ABCC1, PRMT5, LEO1, LMNB2, USP8, DARS, GYS1, APEH, ZYG11B, AKAP1, ELAVL1, MCM5, LRWD1, PSMC1, MOGS, TRIM28, EXOC6, LUC7L3, ANKFY1, NSUN2, HDAC2, G3BP1, QRICH1, INTS3, UBR1, XAB2, DYNC1LI1, TUFM, GAA, EXOC8, DHX8, LIMCH1, CLTC, SRPR, RNH1, ABI2, AQR, PREP, PPM1E, COG2, SEPT9, IDH2, MFN2, EXOC4, VPS33B, INTS4, GNB1, MSH6, HNRNPC, ERLIN1, EPRS, LRRC49, RPAP1, MCM3, PSMC4, PSMD3, GNL1, TRIP13, CUX1, PFAS, MAP1S, LRCH1, MRPL19, ABCD1, EIF3F, PDS5B, SMC3, KIF4A, FANCD2, IRF2BP1, SMC1A, RNF20, CLPX, NOC2L, DLAT, CTBP1, APPL1, NAA35, VPS45, PUM2, RELA, NUP210, RANBP9, DNAJC9, WRN, PRKAA1, AIMP2, VPS8, MAD1L1, MRE11A, ATP13A1, ATG7, CEP131, TRIM33, SLC25A10, HERC4, LRRFIP1, POLR1C, IPO9, GEMIN5, METAP2, SMG8, WASL, PPP1CB, SCFD1, RANBP3, RB1, CLTA, RNF40, SNRNP70, NCSTN, MGEA5, NARS, EIF4E, INPP4A, TFB2M, SEL1L, ARGLU1, PPP4R1, ANKRD17, TTK, RAD50, KIF2C, GOLGA3, TRAPPC11, GIGYF2, MSI2, CYFIP2, CDK5, HBS1L, IFT81, UFL1, PFKM, SMARCAD1, WDR35, PRIM2, NAMPT, PSMD2, MSH2, SOGA3, HEATR6, SFXN1, ARCN1, OGDH, FDPS, PSMC5, INSR, IRF2BP2, DDOST, ATXN2L, CSNK2A1, EIF2S2, MAP4, LTN1, COPB1, BRAT1, SMC6, SNRPN, RIC8A, SKIV2L, EIF4A1, KIF15, CLPTM1L, KPNA1, VPS16, VPS26B, RNPEP, RBM39, PMS1, FAM129B, RFC3, NUP155, RBM26, KIF21A, GAPVD1, C2CD5, WAPAL, RPS13, ARHGEF1, ACTR1A, KLC4, ISLR2, DCK, LRRC8A, STT3A, BOP1, RPN2, AFTPH, ORC3, FOXK1, CD2BP2, PDHA1, PPP6R1, PANK4, KIAA0196, WDR77, CHUK, DDX1, COLGALT1, VAPA, PPME1, CAMSAP1, RABL6, RTCB, SRRT, PIK3C3, NUMA1, STXBP1, OTUB1, UBAP2L, EXOC5, LRRC59, EXOC3, RQCD1, FLII, COPG2, USP5, XPOT, TIMM44, ATP1A1, SBF1, ARPC1B, PLK1, OSBPL8, BAG6, PPP6R2, FAM98B, VPS52, FADS2, EIF4G2, EIF4G3, HSPA8, POLR1B, PSMC6, SFSWAP, VPS33A, MCM10, AVL9, RINT1, PPIB, FBXL18, MFAP1, KIF13B, ATP2C1, ERCC2, CTTNBP2NL, WDR82, VARS, KPNA6, MIA3, HEATR1, SEC23B, AASDHPPT, POLR3B, ALDH18A1, PIKFYVE, MPP6, MRI1, CAPN7, RAB3GAP2, NCAPD2, UGGT1, IKBKAP, KDM3B, CLNS1A, FEN1, ECH1, AP2B1, HNRNPH1, RARS, AGPS, FANCI, PYCR2, EHD1, BUB3, KIF5B, SYMPK, PC, ACAA2, NDC80, PRRC2C, MTHFD1L, FASN, RANBP6, VPS11, NUP93, STRN, SCYL1, DDX19A, GTF2I, SEC23A, CTNNB1, STAM, VPRBP, VCL, PDHB, SEC24D, ERCC4, GRN, ACADM, HSPA6, ERCC6L, RPL5, ARHGAP17, DDX6, MAPK8IP3, TJP1, RIOK1, ERP29, PARG, NUP205, PALLD, COG4, TPP2, EPB41, VAC14, FUS, ZW10, KIF11, GET4, MCM6, EIF2S1, CSDE1, DHX16, GFM1, RABGAP1, TTC28, XPO1, EXOC2, DCTN1, ACBD3, RFC4, PARP1, COPG1, GPRIN1, EIF3C, CUL1, C14orf166, RTL1, STRIP1, MRPS2, PPP2R5D, EIF4G1, EXOSC4, MCM4, SEC63, WDR1, CUL4B, CRMP1, NSF, RNMT, BLVRA, UBE4A, PCBP1, MLLT4, RNF214, ARVCF, CKAP5, NUP188, SMCR8, CTNNA1, SYT1, PCM1, KNTC1, GFPT1, THYN1, SARM1, LPIN1, TIA1, NUP54, PKN1, SUMO4, DICER1, KIF3A, IPO8, CLIC4, PSMD14, GLG1, ABCE1, SMEK1, NCAPG, PPP5C, RTF1, IARS2, PDS5A, PHGDH, RPS6KA3, LONP1, ROCK1, CDK6, LARS, KPNA3, HNRNPAB, MCM2, PPP2R2A, HSP90AB2P, VCPIP1, PCBP2, RPA1, SEC24A, HECTD3, RCC2, DIS3, SMS, KHSRP, CLGN, GNAS, FOCAD, SEC23IP, ACOT7, HK2, CCDC6, MFN1, WDR7, CNN3, KIAA1524, RAB3GAP1, OXCT1, SBNO1, PRPSAP2, ACTR3, CTPS2, TMEM43, FAM21A, LRRC47, VAPB, SCYL2, STRN4, NAE1, SREK1, TFG, SF3A1, CDK2, GPKOW, GPHN, PDCD4, U2AF2, UNC45A, VPS35, NAA15, ASNS, TOP2B, ACO2, AGAP3, ROCK2, NUDT21, NPEPPS, ADD1, AP1G1, CPSF6, DNAJC2, RPS5, CTPS1, IDH1, SEC24C, KIF3B, ACTR2, CPD, EEF1D, SAMHD1, ETFB, DNM1L, LRPPRC, MCMBP, RBM12, OPA1, FARSB, UPF1, PCMT1, USO1, COG3, CLPTM1, TLK2, PRUNE, ASPSCR1, MARS, PYCR1, TCERG1, MED23, PITPNB, ARPC2, UBE4B, DBR1, ETFA, BICD1, KLC1, WDR70, PXDN, DPYSL4, USP7, CLUH, TBRG4, OGFR, SV2A, PDCD6IP, PDLIM5, PSMC2, TRAP1, DRG1, SMEK2, TCP1, TNPO2, CALD1, ARIH2, POR, FKBP3, DCTN2, NPM1, USP48, IPO13, NUP88, NNT, TAOK1, PPWD1, PSPC1, PABPN1, POLA1, MTR, BCCIP, RUVBL2, C16orf62, SORD, PPP2CA, STRN3, RUVBL1, PPP1CA, CACTIN, RPAP3, VPS51, TUBB3, PRKDC, HSPA5, CCDC132, MRPS27, RBBP4, CAPZA1, SLC4A1AP, THUMPD3, FAF1, CDK4, GSTO1, NCBP1, CAPZB, SNRPA, TXLNG, NELFE, MUT, DYNC1LI2, CTTN, DYNC1I2, TIMELESS, CBS, TTLL12, ESYT1, LAMB1, KARS, PPIL4, LRRC40, TXLNA, RAD23B, TBCE, ACAD9, THADA, GCN1L1, SLK, PNKP, ACLY, ATP6V0A1, VTA1, TXNDC5, OXSR1, ACACA, TNPO3, CCDC93, TIPRL, RAN, HOOK3, PSME4, YWHAQ, PPM1G, PSMC3, SCARB2, EXOC7, DFNA5, TRMT6, CPNE3, SLC3A2, G6PD, EIF2B1, SF3B1, EXOC6B, HGS, DYNC1H1, DNAJC7, CANX, TSR1, TTC37, DARS2, ZPR1, SERBP1, HSP90AB1, TBCB, UCHL5, IMPDH2, PUF60, RANGAP1, PDXDC1, YWHAH, LARS2, ZC3H15, GMPS, YWHAG, SUPV3L1, SPAG9, IMPDH1, HSD17B10, GTF2F1, EXOSC9, CUL3, ARHGAP35, TUBB4B, EIF5B, KIF5C, PDIA6, LDHA, ATL2, SNX1, SF3B3, SRM, MAP2, DIAPH1, DBH, NHLRC2, ELP2, GRPEL1, TWF1, WBP11, ERP44, SERPINB6, VCP, HSPH1, CMTR1, KIF1A, USP47, EML4, PRMT1, ATP6V1B2, GPS1, CAND1, CLPB, PCNA, RPLP0, CORO7, TUBB, ANXA2, API5, SUPT16H, RUFY1, KIAA1279, PDIA3, ACTA1, SF3A3, DCTN4, CUL2, WARS, PGM2, NELFB, XPO5, UGP2, HSP90B1, GSR, SHMT2, IPO11, EIF3E, RDX, DNAJB1, KIAA1598, AARS, EFTUD1, HEATR5B, ENAH, TNPO1, LIG1, NRD1, DLD, STRA6, PAFAH1B1, NT5C2, SSRP1, NTRK3, HDGFRP2, EIF3G, CSE1L, ACAT1, TBCD, NAA10, MTHFD1, RALA, EIF3A, PRPS1, ISOC1, IPO7, HNRNPD, GAPDH, U2AF1, SUPT5H, PSMD8, RPS6KA1, NUF2, GDAP1, VPS26A, TUBB2B, CDH2, TMOD1, CBR1, HDLBP, CS, HSPD1, LMAN1, EIF3B, DDB1, PSMD1, DPYSL2, STRAP, RTN4, FLNA, AHCY, HSD17B4, GOLIM4, SPTAN1, IPO4, PKM, EIF3I, SF1, BZW2, XPO7, ACADVL, STAG2, DPP9, RECQL, GDI1, GARS, MMS19, EIF2A, IPO5, TCOF1, RAB5C, SAP30BP, VDAC1, TUBA1A, SEPT2, DBNL, PLAA, TOMM70A, NOMO1, ISYNA1, CTNNA2, EEF1B2, PAK4, NELFCD, GSPT1, KPNB1, MAP1A, COPS4, YWHAZ, KPNA2, EIF4B, PLS3, COPS3, HSPBP1, AP1B1, NASP, DDX39A, LUC7L2, APMAP, SEC31A, SRSF2, TXNRD1, ATP1A3, RRM2, COG7, FSD1, PRDX4, DCPS, NCAM1, NUDCD1, NAA25, RPL9, NPLOC4, YWHAB, ATP1B1, LSS, DNAAF5, METTL16, COPS6, XPNPEP1, ELAC2, PUS7, CCT3, SFN, AGL, PAPOLA, SRSF11, ALDH2, PSME2, CKMT1B, LDHB, PSMA7, RAB11A, PPP2R1A, GNAO1, LUC7L, COPS5, IMPA1, RRM1, PPID, DPP3, KIAA0368, SLC1A5, YARS, NUP50, TPM4, ITGB1, SARS, SEZ6L2, GTF2F2, GART, ALDOC, PSMD11, EIF6, DFFA, RAP1GDS1, NELFA, CARS, CCT4, P4HB, FSCN1, PSMD13, PSMA5, CCT5, PAPSS1, OSBP, SAE1, ATP6V1A, LMAN2, YWHAE, SRP54, IDE, SNX2, RPSA, BZW1, SND1, UBQLN1, MAPK1, CALR, MARCKSL1, SUGT1, TBC1D4, GLRX3, LETM1, HMGB1, EIF3H, SLC9A3R1, DDX42, LAP3, PRKCSH, EEF2, PSMD6, BCAP31, ANXA11, ACTN1, CCT6A, PSMA4, ANXA5, CCT7, EIF3L, FUBP1, SSB, PGM1, MAPRE1, UBA2, AMPD2, PPAT, CLIC1, CCT2, ECHS1, LTA4H, USP14, CCT8, ANK2, PDIA4, TPR, NRCAM, MAT2A, HTATSF1, THOP1, RANBP1, RSRC2, NMT1, AK2, EEF1G, TPM3, PSMA3, EIF4H, GLUD1, CAP1, TKT, ATP5B, TXNL1, STIP1, HMGB2, GGH, HSPB1, CALU, RPL17, PSMA1, RSRC1, ST13, PRDX6, EIF3J, PNPT1, APEX1, TARS, MARCKS, PSMA6, EEF1A1, COPB2, NUDT5, HSPA1A, ERO1L, ME2, RPH3A, ESD, EIF5, ADSL, RUFY3, DPYSL5, ANXA6, NUDC, NANS, GOT2, GLDC, PSAT1, SET, PAK2, UBA6, UCHL1, L1CAM, PGLS, MAP1B, CCDC124, EIF3M, VAT1, PAFAH1B3, ALDOA, IRGQ, UBQLN2, NACA, OLA1, ACTN4, ARHGDIA, PSMD7, CACYBP, PSMA2, CPNE1, MDH2, PGAM1, DDX46, ACAT2, ALCAM, HARS, CKB, FKBP4, ASNA1, GPI, INA, HYOU1, CHGA, MDH1, EZR, ANP32A, UBA1, ARG1, ANP32B, PAICS, ATIC, TPI1, PPA1, TALDO1, PGK1, DDX39B, TLN1, AKR1B1, ENO1, NGFR, TPTE, GGA1, GGA2, GGA3, USP36, NDFIP1, SOCS2, CDK12, EPHB4, NDUFA4L2, AKT1, SLC5A5, DOT1L, AKT2, SHC4, TRAF4, PTPN6, ERBB2, EGR1, HIPK2, POU4F2,
SSBP2	EWSR1, LDB1, IL36RN, TAL1, LMO2, TRIM33, DYRK2, CDK6, BAG3, TOM1, LDB2, LMX1B, IDI2, ISL2, ISL1, SSBP4, SSBP3, CLEC18A, LMO4, LHX4, LHX6, PIN1, ARHGAP22, ARHGEF10, CAMK2A, FPR1, RRD1, CBFA2T3, NABP1, INTS3, MYH9, ACACA, PC, MCCC2, MCCC1, EP300, PYGO1, BCL9, ORC6, BCL9L, LHX3, MFAP4, LMO1, LMO3, PICK1, VIM, S100A7A, HLA-DRB1, HMOX1, NDRG2, LCP1, IGHG1, IGHG2, TYMP, HIST1H2AG, HLA-DRA, PPL, IL36G, HIST1H1B, NDRG1, IVL, TREX2, IL1RN, GLUL, EVPL, SERPINA1, MNDA, TF, TRIM29, SERPINB3, SERPINB4, SERPINB2, C3, HLA-DQB1, HLA-DPB1, LGALS7B, FGB, SERPINB7, CBR1, ALOX15, IGKC, STAT3, SULT2B1, CALML3, PYCARD, CALML5, IGLL5, H2AFY, T, GATA2, LHX1, LHX2, LHX8, TEAD1, TLX1,

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
SSBP2
NTRK1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to SSBP2-NTRK1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to SSBP2-NTRK1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	SSBP2	C0005586	Bipolar Disorder	1	CTD_human
Hgene	SSBP2	C0005587	Depression, Bipolar	1	CTD_human
Hgene	SSBP2	C0024713	Manic Disorder	1	CTD_human
Hgene	SSBP2	C0033578	Prostatic Neoplasms	1	CTD_human
Hgene	SSBP2	C0338831	Manic	1	CTD_human
Hgene	SSBP2	C0376358	Malignant neoplasm of prostate	1	CTD_human
Tgene	NTRK1	C0020074	HSAN Type IV	17	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene	NTRK1	C0238463	Papillary thyroid carcinoma	3	ORPHANET
Tgene	NTRK1	C0002768	Congenital Pain Insensitivity	1	ORPHANET
Tgene	NTRK1	C0005586	Bipolar Disorder	1	CTD_human
Tgene	NTRK1	C0005587	Depression, Bipolar	1	CTD_human
Tgene	NTRK1	C0017638	Glioma	1	CTD_human
Tgene	NTRK1	C0020075	Hereditary Sensory Autonomic Neuropathy, Type 5	1	CTD_human;ORPHANET
Tgene	NTRK1	C0024713	Manic Disorder	1	CTD_human
Tgene	NTRK1	C0027796	Neuralgia	1	CTD_human
Tgene	NTRK1	C0027819	Neuroblastoma	1	CTD_human
Tgene	NTRK1	C0033958	Psychosis, Brief Reactive	1	CTD_human
Tgene	NTRK1	C0033975	Psychotic Disorders	1	CTD_human
Tgene	NTRK1	C0036337	Schizoaffective Disorder	1	CTD_human
Tgene	NTRK1	C0036341	Schizophrenia	1	CTD_human
Tgene	NTRK1	C0036358	Schizophreniform Disorders	1	CTD_human
Tgene	NTRK1	C0038870	Neuralgia, Supraorbital	1	CTD_human
Tgene	NTRK1	C0042656	Neuralgia, Vidian	1	CTD_human
Tgene	NTRK1	C0234247	Neuralgia, Atypical	1	CTD_human
Tgene	NTRK1	C0234249	Neuralgia, Stump	1	CTD_human
Tgene	NTRK1	C0259783	mixed gliomas	1	CTD_human
Tgene	NTRK1	C0273115	Lung Injury	1	CTD_human
Tgene	NTRK1	C0338831	Manic	1	CTD_human
Tgene	NTRK1	C0423711	Neuralgia, Perineal	1	CTD_human
Tgene	NTRK1	C0423712	Neuralgia, Iliohypogastric Nerve	1	CTD_human
Tgene	NTRK1	C0555198	Malignant Glioma	1	CTD_human
Tgene	NTRK1	C0598589	Inherited neuropathies	1	GENOMICS_ENGLAND
Tgene	NTRK1	C0751371	Neuralgia, Ilioinguinal	1	CTD_human
Tgene	NTRK1	C0751372	Nerve Pain	1	CTD_human
Tgene	NTRK1	C0751373	Paroxysmal Nerve Pain	1	CTD_human
Tgene	NTRK1	C0752347	Lewy Body Disease	1	CTD_human
Tgene	NTRK1	C1833921	Familial medullary thyroid carcinoma	1	CTD_human;GENOMICS_ENGLAND;ORPHANET
Tgene	NTRK1	C2350344	Chronic Lung Injury	1	CTD_human