UTHEALTH HOME ABOUT SBMI A-Z WEBMAIL INSIDE THE UNIVERSITY

Home

Download

Statistics

Examples

Help

Contact

level1

	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:TXNRD1-CHST11

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: TXNRD1-CHST11
	FusionPDB ID: 95606
	FusionGDB2.0 ID: 95606
		Hgene	Tgene
	Gene symbol	TXNRD1	CHST11
	Gene ID	7296	50515
	Gene name	thioredoxin reductase 1	carbohydrate sulfotransferase 11
	Synonyms	GRIM-12\|TR\|TR1\|TRXR1\|TXNR	C4ST\|C4ST-1\|C4ST1\|HSA269537\|OCBMD
	Cytomap	12q23.3	12q23.3
	Type of gene	protein-coding	protein-coding
	Description	thioredoxin reductase 1, cytoplasmicKM-102-derived reductase-like factorgene associated with retinoic and IFN-induced mortality 12 proteingene associated with retinoic and interferon-induced mortality 12 proteinoxidoreductasetestis tissue sperm-bindi	carbohydrate sulfotransferase 11C4S-1IgH/CHST11 fusioncarbohydrate (chondroitin 4) sulfotransferase 11chondroitin 4-O-sulfotransferase 1
	Modification date	20200313	20200313
	UniProtAcc	.	Q9NPF2
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000354940, ENST00000378070, ENST00000388854, ENST00000397736, ENST00000427956, ENST00000429002, ENST00000503506, ENST00000524698, ENST00000525566, ENST00000526390, ENST00000526691, ENST00000526950, ENST00000529546, ENST00000540716, ENST00000542918, ENST00000526006,	ENST00000303694, ENST00000546689, ENST00000547956, ENST00000549260, ENST00000550711,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	30 X 25 X 8=6000	14 X 13 X 7=1274
	# samples	37	16
	** MAII score	log2(37/6000*10)=-4.01936532486693 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/1274*10)=-2.99322146736894 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: TXNRD1 [Title/Abstract] AND CHST11 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	CHST11(104995769)-TXNRD1(104732917), # samples:2 TXNRD1(104682818)-CHST11(104995683), # samples:1 TXNRD1(104733051)-CHST11(104995683), # samples:1 TXNRD1(104733050)-CHST11(104858480), # samples:1
Anticipated loss of major functional domain due to fusion event.	CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. CHST11-TXNRD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. CHST11-TXNRD1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. TXNRD1-CHST11 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	CHST11	GO:0030206	chondroitin sulfate biosynthetic process	11056388

Fusion gene breakpoints across TXNRD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CHST11 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Top

Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-DK-A6AV	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+
ChimerDB4	ESCA	TCGA-VR-A8ER	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+
ChimerDB4	LUSC	TCGA-63-A5MJ-01A	TXNRD1	chr12	104733050	+	CHST11	chr12	104858480	-

Top

Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000525566	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	812	438	15	527	170
ENST00000525566	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	680	438	15	527	170
ENST00000429002	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	810	436	13	525	170
ENST00000429002	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	678	436	13	525	170
ENST00000526691	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	950	576	661	149	170
ENST00000526691	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	818	576	661	149	170
ENST00000388854	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	882	508	593	81	170
ENST00000388854	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	750	508	593	81	170
ENST00000542918	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	548	174	3	263	86
ENST00000542918	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	416	174	3	263	86
ENST00000378070	TXNRD1	chr12	104682818	+	ENST00000547956	CHST11	chr12	104995683	+	697	323	408	46	120
ENST00000378070	TXNRD1	chr12	104682818	+	ENST00000546689	CHST11	chr12	104995683	+	565	323	408	46	120
ENST00000525566	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2279	1905	15	1994	659
ENST00000525566	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2147	1905	15	1994	659
ENST00000429002	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2277	1903	13	1992	659
ENST00000429002	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2145	1903	13	1992	659
ENST00000503506	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2379	2005	442	2094	550
ENST00000503506	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2247	2005	442	2094	550
ENST00000526691	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2417	2043	297	2132	611
ENST00000526691	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2285	2043	297	2132	611
ENST00000388854	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2349	1975	229	2064	611
ENST00000388854	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2217	1975	229	2064	611
ENST00000354940	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2239	1865	434	1954	506
ENST00000354940	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2107	1865	434	1954	506
ENST00000526390	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2260	1886	257	1975	572
ENST00000526390	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2128	1886	257	1975	572
ENST00000529546	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	1916	1542	102	1631	509
ENST00000529546	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1784	1542	102	1631	509
ENST00000540716	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	1906	1532	92	1621	509
ENST00000540716	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1774	1532	92	1621	509
ENST00000524698	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2015	1641	3	1730	575
ENST00000524698	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1883	1641	3	1730	575
ENST00000542918	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2015	1641	3	1730	575
ENST00000542918	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1883	1641	3	1730	575
ENST00000378070	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2164	1790	53	1879	608
ENST00000378070	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2032	1790	53	1879	608
ENST00000397736	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	1937	1563	0	1652	550
ENST00000397736	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1805	1563	0	1652	550
ENST00000427956	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2150	1776	0	1865	621
ENST00000427956	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	2018	1776	0	1865	621
ENST00000526950	TXNRD1	chr12	104733051	+	ENST00000547956	CHST11	chr12	104995683	+	2090	1716	78	1805	575
ENST00000526950	TXNRD1	chr12	104733051	+	ENST00000546689	CHST11	chr12	104995683	+	1958	1716	78	1805	575

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000525566	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.034653578	0.9653464
ENST00000525566	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.036731906	0.96326816
ENST00000429002	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.038293008	0.96170706
ENST00000429002	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.038059708	0.9619403
ENST00000526691	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.5042946	0.49570546
ENST00000526691	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.4665892	0.5334108
ENST00000388854	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.33817282	0.6618272
ENST00000388854	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.45829776	0.5417022
ENST00000542918	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.24216817	0.7578318
ENST00000542918	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.4258527	0.5741473
ENST00000378070	ENST00000547956	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.34544665	0.65455335
ENST00000378070	ENST00000546689	TXNRD1	chr12	104682818	+	CHST11	chr12	104995683	+	0.36937997	0.63062
ENST00000525566	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.003796549	0.9962035
ENST00000525566	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.003018425	0.99698156
ENST00000429002	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.00388563	0.9961144
ENST00000429002	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.00309839	0.99690163
ENST00000503506	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001798488	0.9982015
ENST00000503506	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001429575	0.99857044
ENST00000526691	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002875163	0.99712485
ENST00000526691	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002406184	0.9975938
ENST00000388854	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002550552	0.99744946
ENST00000388854	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.00206544	0.9979346
ENST00000354940	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002024411	0.99797565
ENST00000354940	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001655016	0.998345
ENST00000526390	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001519517	0.9984805
ENST00000526390	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001211716	0.9987883
ENST00000529546	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001694121	0.9983059
ENST00000529546	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001219885	0.9987801
ENST00000540716	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001735936	0.99826413
ENST00000540716	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001248938	0.99875104
ENST00000524698	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002456495	0.9975435
ENST00000524698	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001803201	0.9981968
ENST00000542918	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.002456495	0.9975435
ENST00000542918	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001803201	0.9981968
ENST00000378070	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001295568	0.99870443
ENST00000378070	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.000956829	0.99904317
ENST00000397736	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.00136515	0.9986349
ENST00000397736	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.000992123	0.9990079
ENST00000427956	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001994635	0.99800533
ENST00000427956	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001601335	0.9983986
ENST00000526950	ENST00000547956	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.001238202	0.9987618
ENST00000526950	ENST00000546689	TXNRD1	chr12	104733051	+	CHST11	chr12	104995683	+	0.000970216	0.99902976

Top

Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>95606_95606_1_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000378070_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=120AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSVWHKSRAERVRCFSPANRRELRRG

--------------------------------------------------------------

>95606_95606_2_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000378070_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=120AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSVWHKSRAERVRCFSPANRRELRRG

--------------------------------------------------------------

>95606_95606_3_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000388854_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=170AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSHDMLKLCVTGSKPHTPRSCLGLEK

--------------------------------------------------------------

>95606_95606_4_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000388854_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=170AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSHDMLKLCVTGSKPHTPRSCLGLEK

--------------------------------------------------------------

>95606_95606_5_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000429002_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=170AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK

--------------------------------------------------------------

>95606_95606_6_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000429002_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=170AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK

--------------------------------------------------------------

>95606_95606_7_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000525566_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=170AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK

--------------------------------------------------------------

>95606_95606_8_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000525566_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=170AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK

--------------------------------------------------------------

>95606_95606_9_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000526691_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=170AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSHDMLKLCVTGSKPHTPRSCLGLEK

--------------------------------------------------------------

>95606_95606_10_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000526691_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=170AA_BP=1
MDWVVEFLQGASGPLPAADVHTKGIPPHDFKVGPWPPIFLCFTNTTGRSVSAANSESVPSRARPSSHDMLKLCVTGSKPHTPRSCLGLEK

--------------------------------------------------------------

>95606_95606_11_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000542918_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=86AA_BP=1

--------------------------------------------------------------

>95606_95606_12_TXNRD1-CHST11_TXNRD1_chr12_104682818_ENST00000542918_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=86AA_BP=1

--------------------------------------------------------------

>95606_95606_13_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000354940_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=506AA_BP=0
MNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKV
EETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISS
DDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVV
AQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAG
STVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQ

--------------------------------------------------------------

>95606_95606_14_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000354940_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=506AA_BP=0
MNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKV
EETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISS
DDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVV
AQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAG
STVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQ

--------------------------------------------------------------

>95606_95606_15_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000378070_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=608AA_BP=1
MSEMQQVMLTCKGVNRGHAVPAGPGRKPRPRRSSRLLAGEKHLTRSALLLCHTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLK
AYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQ
ALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYL
GIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQ
IEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQ
AGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGF

--------------------------------------------------------------

>95606_95606_16_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000378070_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=608AA_BP=1
MSEMQQVMLTCKGVNRGHAVPAGPGRKPRPRRSSRLLAGEKHLTRSALLLCHTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLK
AYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQ
ALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYL
GIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQ
IEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQ
AGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGF

--------------------------------------------------------------

>95606_95606_17_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000388854_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=611AA_BP=1
MPAGTTALRLGAAVCVSGKGRYFKACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGP
TLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAAL
LGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERP
RYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK
VEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPV
AIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERV

--------------------------------------------------------------

>95606_95606_18_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000388854_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=611AA_BP=1
MPAGTTALRLGAAVCVSGKGRYFKACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGP
TLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAAL
LGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERP
RYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK
VEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPV
AIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERV

--------------------------------------------------------------

>95606_95606_19_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000397736_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=550AA_BP=0
MLSRLVLNSWAQAIIRPRPPKVLGLQVTTFSEAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP
TPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIG
PHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLR
GFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKI
PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYF
WPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAESCGGIPLVWTSAAGRGPEA

--------------------------------------------------------------

>95606_95606_20_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000397736_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=550AA_BP=0
MLSRLVLNSWAQAIIRPRPPKVLGLQVTTFSEAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP
TPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIG
PHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLR
GFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKI
PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYF
WPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAESCGGIPLVWTSAAGRGPEA

--------------------------------------------------------------

>95606_95606_21_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000427956_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=621AA_BP=0
MPVDDYWLCLPASCARPFVQTVRVVQSCPHCCWFPGVLPSVPEPLRMPAMLPTGSHSAVLPPSHCSTAPPSTSQEPSSSADPKLCLSPPT
SDSRQERNVQFGLAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCI
PKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAE
RFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI
KFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDI
LEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI

--------------------------------------------------------------

>95606_95606_22_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000427956_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=621AA_BP=0
MPVDDYWLCLPASCARPFVQTVRVVQSCPHCCWFPGVLPSVPEPLRMPAMLPTGSHSAVLPPSHCSTAPPSTSQEPSSSADPKLCLSPPT
SDSRQERNVQFGLAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCI
PKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAE
RFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGI
KFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDI
LEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI

--------------------------------------------------------------

>95606_95606_23_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000429002_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=659AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK
SLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAA
AKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYR
VALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG
FLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACT
RKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSE
EKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE

--------------------------------------------------------------

>95606_95606_24_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000429002_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=659AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK
SLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAA
AKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYR
VALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG
FLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACT
RKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSE
EKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE

--------------------------------------------------------------

>95606_95606_25_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000503506_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=550AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP
TPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIG
PHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLR
GFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKI
PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYF
WPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAESCGGIPLVWTSAAGRGPEA

--------------------------------------------------------------

>95606_95606_26_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000503506_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=550AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTP
TPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIG
PHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLR
GFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKI
PVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYF
WPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAESCGGIPLVWTSAAGRGPEA

--------------------------------------------------------------

>95606_95606_27_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000524698_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=575AA_BP=1
MAVSFLLVFVETVCRTAEKMEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

>95606_95606_28_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000524698_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=575AA_BP=1
MAVSFLLVFVETVCRTAEKMEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

>95606_95606_29_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000525566_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=659AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK
SLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAA
AKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYR
VALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG
FLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACT
RKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSE
EKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE

--------------------------------------------------------------

>95606_95606_30_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000525566_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=659AA_BP=1
MCDMGCAEGKAVAAAAPTELQTKGKNGDGRRRSAKDHHPGKTLPENPAGFTSTATADSRALLQAYIDGHSVVIFSRSTCTRCTEVKKLFK
SLCVPYFVLELDQTEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAA
AKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYR
VALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAG
FLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACT
RKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSE
EKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE

--------------------------------------------------------------

>95606_95606_31_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526390_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=572AA_BP=1
MEESNQEALGVTSFSFRDGGLIMLSRLVLNSWAQAIIRPRPPKVLGLQVTTFSEAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGG
LAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNW
GYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALE
CAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRD
ACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACG
LSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPV

--------------------------------------------------------------

>95606_95606_32_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526390_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=572AA_BP=1
MEESNQEALGVTSFSFRDGGLIMLSRLVLNSWAQAIIRPRPPKVLGLQVTTFSEAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGG
LAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNW
GYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALE
CAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRD
ACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACG
LSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIHPV

--------------------------------------------------------------

>95606_95606_33_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526691_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=611AA_BP=1
MPAGTTALRLGAAVCVSGKGRYFKACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGP
TLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAAL
LGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERP
RYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK
VEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPV
AIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERV

--------------------------------------------------------------

>95606_95606_34_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526691_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=611AA_BP=1
MPAGTTALRLGAAVCVSGKGRYFKACLSRRGGFSKPRQLRGVCGFDPVTQSFSMSCEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGP
TLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAAL
LGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERP
RYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIK
VEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPV
AIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERV

--------------------------------------------------------------

>95606_95606_35_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526950_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=575AA_BP=0
MPAMLPTGSHSAVLPPSHCSTAPPSTSQEPSSSADPKLCLSPPTSDSRQERNVQFGLAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

>95606_95606_36_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000526950_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=575AA_BP=0
MPAMLPTGSHSAVLPPSHCSTAPPSTSQEPSSSADPKLCLSPPTSDSRQERNVQFGLAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

>95606_95606_37_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000529546_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=509AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYG
WKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYC
ISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRL
RVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRL
YAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGE

--------------------------------------------------------------

>95606_95606_38_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000529546_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=509AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYG
WKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYC
ISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRL
RVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRL
YAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGE

--------------------------------------------------------------

>95606_95606_39_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000540716_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=509AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYG
WKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYC
ISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRL
RVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRL
YAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGE

--------------------------------------------------------------

>95606_95606_40_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000540716_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=509AA_BP=1
MEGTLSELAAETDLPVVFVKQRKIGGHGPTLKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYG
WKVEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYC
ISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRL
RVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRL
YAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGE

--------------------------------------------------------------

>95606_95606_41_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000542918_CHST11_chr12_104995683_ENST00000546689_length(amino acids)=575AA_BP=1
MAVSFLLVFVETVCRTAEKMEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

>95606_95606_42_TXNRD1-CHST11_TXNRD1_chr12_104733051_ENST00000542918_CHST11_chr12_104995683_ENST00000547956_length(amino acids)=575AA_BP=1
MAVSFLLVFVETVCRTAEKMEDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLLKMNGPEDLPKSYDYDLIIIGGG
SGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWKVEETVKHDWDRMIEAVQNHIGS
LNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLFSLPYCPGKTLVVGASYV
ALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAI
GRDACTRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYG
ACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGI

--------------------------------------------------------------

Top

Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:104995769/chr12:104732917)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	CHST11 Q9NPF2
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000388854

56_156

529.0

550.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000503506

56_156

477.0

500.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000524698

56_156

477.0

500.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000525566

56_156

627.0

650.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000526390

56_156

521.0

544.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000526691

56_156

529.0

552.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000388854

192_209

529.0

550.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000503506

192_209

477.0

500.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000524698

192_209

477.0

500.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000525566

192_209

627.0

650.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000526390

192_209

521.0

544.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104733051

chr12:104995683

ENST00000526691

192_209

529.0

552.0

Nucleotide binding

FAD

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000303694

124_130

39.333333333333336

353.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000303694

186_194

39.333333333333336

353.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000549260

124_130

34.333333333333336

348.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000549260

186_194

34.333333333333336

348.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000303694

124_130

39.333333333333336

353.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000303694

186_194

39.333333333333336

353.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000549260

124_130

34.333333333333336

348.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000549260

186_194

34.333333333333336

348.0

Nucleotide binding

PAPS

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000303694

38_352

39.333333333333336

353.0

Topological domain

Lumenal

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000549260

38_352

34.333333333333336

348.0

Topological domain

Lumenal

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000303694

38_352

39.333333333333336

353.0

Topological domain

Lumenal

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000549260

38_352

34.333333333333336

348.0

Topological domain

Lumenal

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000388854

56_156

40.0

550.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000503506

56_156

500.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000524698

56_156

500.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000525566

56_156

138.0

650.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000526390

56_156

544.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000526691

56_156

40.0

552.0

Domain

Glutaredoxin

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000388854

192_209

40.0

550.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000503506

192_209

500.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000524698

192_209

500.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000525566

192_209

138.0

650.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000526390

192_209

544.0

Nucleotide binding

FAD

Hgene

TXNRD1

chr12:104682818

chr12:104995683

ENST00000526691

192_209

40.0

552.0

Nucleotide binding

FAD

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000303694

1_16

39.333333333333336

353.0

Topological domain

Cytoplasmic

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000549260

1_16

34.333333333333336

348.0

Topological domain

Cytoplasmic

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000303694

1_16

39.333333333333336

353.0

Topological domain

Cytoplasmic

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000549260

1_16

34.333333333333336

348.0

Topological domain

Cytoplasmic

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000303694

17_37

39.333333333333336

353.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

CHST11

chr12:104682818

chr12:104995683

ENST00000549260

17_37

34.333333333333336

348.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000303694

17_37

39.333333333333336

353.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Tgene

CHST11

chr12:104733051

chr12:104995683

ENST00000549260

17_37

34.333333333333336

348.0

Transmembrane

Helical%3B Signal-anchor for type II membrane protein

Top

Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
TXNRD1
CHST11

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs to TXNRD1-CHST11

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

Top

Related Diseases to TXNRD1-CHST11

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source