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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein Structure
	pLDDT scores
	Ramachandran Plot of Fusion Protein Structure
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:VTI1A-HDAC1

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: VTI1A-HDAC1
	FusionPDB ID: 98590
	FusionGDB2.0 ID: 98590
		Hgene	Tgene
	Gene symbol	VTI1A	HDAC1
	Gene ID	143187	3065
	Gene name	vesicle transport through interaction with t-SNAREs 1A	histone deacetylase 1
	Synonyms	MMDS3\|MVti1\|VTI1RP2\|Vti1-rp2	GON-10\|HD1\|KDAC1\|RPD3\|RPD3L1
	Cytomap	10q25.2	1p35.2-p35.1
	Type of gene	protein-coding	protein-coding
	Description	vesicle transport through interaction with t-SNAREs homolog 1ASNARE Vti1a-beta proteinvesicle transport v-SNARE protein Vti1-like 2	histone deacetylase 1reduced potassium dependency, yeast homolog-like 1
	Modification date	20200313	20200327
	UniProtAcc	Q96AJ9	Q96DB2
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000393077, ENST00000432306, ENST00000483122,	ENST00000373541, ENST00000490081, ENST00000373548,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	15 X 12 X 12=2160	12 X 11 X 6=792
	# samples	24	13
	** MAII score	log2(24/2160*10)=-3.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(13/792*10)=-2.60698880705116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: VTI1A [Title/Abstract] AND HDAC1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	VTI1A(114298089)-HDAC1(32790080), # samples:3
Anticipated loss of major functional domain due to fusion event.	VTI1A-HDAC1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. VTI1A-HDAC1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	VTI1A	GO:0042147	retrograde transport, endosome to Golgi	15215310\|18195106
Tgene	HDAC1	GO:0000122	negative regulation of transcription by RNA polymerase II	18854353
Tgene	HDAC1	GO:0006476	protein deacetylation	17172643\|23629966
Tgene	HDAC1	GO:0045893	positive regulation of transcription, DNA-templated	16762839
Tgene	HDAC1	GO:0045944	positive regulation of transcription by RNA polymerase II	16762839
Tgene	HDAC1	GO:0060766	negative regulation of androgen receptor signaling pathway	15919722
Tgene	HDAC1	GO:0070932	histone H3 deacetylation	12590135
Tgene	HDAC1	GO:0070933	histone H4 deacetylation	12590135

Fusion gene breakpoints across VTI1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HDAC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	UCS	TCGA-N9-A4Q1-01A	VTI1A	chr10	114298089	-	HDAC1	chr1	32790080	+
ChimerDB4	UCS	TCGA-N9-A4Q1-01A	VTI1A	chr10	114298089	+	HDAC1	chr1	32790080	+
ChimerDB4	UCS	TCGA-N9-A4Q1	VTI1A	chr10	114298089	+	HDAC1	chr1	32790079	+
ChimerDB4	UCS	TCGA-N9-A4Q1	VTI1A	chr10	114298089	+	HDAC1	chr1	32790080	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000432306

VTI1A

chr10

114298089

ENST00000373548

HDAC1

chr1

32790080

2303

543

1711

541

ENST00000393077

VTI1A

chr10

114298089

ENST00000373548

HDAC1

chr1

32790080

2303

543

1711

541

ENST00000432306

VTI1A

chr10

114298089

ENST00000373548

HDAC1

chr1

32790079

2303

543

1711

541

ENST00000393077

VTI1A

chr10

114298089

ENST00000373548

HDAC1

chr1

32790079

2303

543

1711

541

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000432306	ENST00000373548	VTI1A	chr10	114298089	+	HDAC1	chr1	32790080	+	0.000557192	0.99944276
ENST00000393077	ENST00000373548	VTI1A	chr10	114298089	+	HDAC1	chr1	32790080	+	0.000557192	0.99944276
ENST00000432306	ENST00000373548	VTI1A	chr10	114298089	+	HDAC1	chr1	32790079	+	0.000557192	0.99944276
ENST00000393077	ENST00000373548	VTI1A	chr10	114298089	+	HDAC1	chr1	32790079	+	0.000557192	0.99944276

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>98590_98590_1_VTI1A-HDAC1_VTI1A_chr10_114298089_ENST00000393077_HDAC1_chr1_32790079_ENST00000373548_length(amino acids)=541AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETVNVGEDCPVFDGLFEFCQLSTGGSVASA
VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDL
RDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGG
GYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE
ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL

--------------------------------------------------------------

>98590_98590_2_VTI1A-HDAC1_VTI1A_chr10_114298089_ENST00000393077_HDAC1_chr1_32790080_ENST00000373548_length(amino acids)=541AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETVNVGEDCPVFDGLFEFCQLSTGGSVASA
VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDL
RDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGG
GYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE
ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL

--------------------------------------------------------------

>98590_98590_3_VTI1A-HDAC1_VTI1A_chr10_114298089_ENST00000432306_HDAC1_chr1_32790079_ENST00000373548_length(amino acids)=541AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETVNVGEDCPVFDGLFEFCQLSTGGSVASA
VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDL
RDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGG
GYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE
ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL

--------------------------------------------------------------

>98590_98590_4_VTI1A-HDAC1_VTI1A_chr10_114298089_ENST00000432306_HDAC1_chr1_32790080_ENST00000373548_length(amino acids)=541AA_BP=152
MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE
MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETVNVGEDCPVFDGLFEFCQLSTGGSVASA
VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDL
RDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGG
GYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE
ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:114298089/chr1:32790080)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
VTI1A Q96AJ9	HDAC1 Q96DB2
FUNCTION: V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. {ECO:0000269\|PubMed:18195106, ECO:0000269\|PubMed:19138172}.	FUNCTION: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. {ECO:0000269\|PubMed:11948178}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000393077

31_92

142.33333333333334

218.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000432306

31_92

142.33333333333334

204.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000393077

31_92

142.33333333333334

218.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000432306

31_92

142.33333333333334

204.0

Coiled coil

Ontology_term=ECO:0000255

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000393077

112_178

142.33333333333334

218.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000432306

112_178

142.33333333333334

204.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000393077

112_178

142.33333333333334

218.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000432306

112_178

142.33333333333334

204.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000393077

1_192

142.33333333333334

218.0

Topological domain

Cytoplasmic

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000393077

214_217

142.33333333333334

218.0

Topological domain

Extracellular

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000432306

1_192

142.33333333333334

204.0

Topological domain

Cytoplasmic

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000432306

214_217

142.33333333333334

204.0

Topological domain

Extracellular

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000393077

1_192

142.33333333333334

218.0

Topological domain

Cytoplasmic

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000393077

214_217

142.33333333333334

218.0

Topological domain

Extracellular

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000432306

1_192

142.33333333333334

204.0

Topological domain

Cytoplasmic

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000432306

214_217

142.33333333333334

204.0

Topological domain

Extracellular

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000393077

193_213

142.33333333333334

218.0

Transmembrane

Helical

Hgene

VTI1A

chr10:114298089

chr1:32790079

ENST00000432306

193_213

142.33333333333334

204.0

Transmembrane

Helical

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000393077

193_213

142.33333333333334

218.0

Transmembrane

Helical

Hgene

VTI1A

chr10:114298089

chr1:32790080

ENST00000432306

193_213

142.33333333333334

204.0

Transmembrane

Helical

Tgene

HDAC1

chr10:114298089

chr1:32790079

ENST00000373548

9_321

93.33333333333333

483.0

Region

Note=Histone deacetylase

Tgene

HDAC1

chr10:114298089

chr1:32790080

ENST00000373548

9_321

93.33333333333333

483.0

Region

Note=Histone deacetylase

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Fusion Protein Structures

PDB and CIF files of the predicted fusion proteins
* Here we show the 3D structure of the fusion proteins using Mol*. AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Model confidence is shown from the pLDDT values per residue. pLDDT corresponds to the model’s prediction of its score on the local Distance Difference Test. It is a measure of local accuracy (from AlphfaFold website). To color code individual residues, we transformed individual PDB files into CIF format.

Fusion protein PDB link (fusion AA seq ID in FusionPDB)	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	AA seq	Len(AA seq)
PDB file >>>1157_VTI1A_114298089_HDAC1_32790080_1157_VTI1A_114298089_HDAC1_32790080_ranked_0.pdb	VTI1A	114298089	114298089	ENST00000373548	HDAC1	chr1	32790080	+	MAWATRSGAAMSSDFEGYEQDFAVLTAEITSKIARVPRLPPDEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRGMYSNRMRSYKQE MGKLETDFKRSRIAYSDEVRNELLGDDGNSSENQRAHLLDNTERLERSSRRLEAGYQIAVETVNVGEDCPVFDGLFEFCQLSTGGSVASA VKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDL RDIGAGKGKYYAVNYPLRDGIDDESYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGGG GYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVKL	541

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pLDDT score distribution

pLDDT score distribution of the predicted wild-type structures of two partner proteins from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

VTI1A_pLDDT.png

HDAC1_pLDDT.png

pLDDT score distribution of the predicted fusion protein structures from AlphaFold2
* AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100.

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Ramachandran Plot of Fusion Protein Structure

Ramachandran plot of the torsional angles - phi (φ)and psi (ψ) - of the residues (amino acids) contained in this fusion protein peptide.

Fusion AA seq ID in FusionPDB and their Ramachandran plots

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene	PPI interactors
VTI1A	VAMP4, VAMP3, STX7, STX8, VAMP8, env, TMBIM6, STX6, STX12, CLEC12A, Snap29, HAUS1, HNRNPL, RNF4, BET1, APEX1, NAPA, VAMP5, ORF7b, ARF6, B3GAT1, LAMP2, LAMP3, LAMTOR1, MARCKS, RAB2A, RAB4A, RAB5A, RAB5C, RAB9A, EDEM1, TRPC4AP, TMEM74, ZDHHC12, SEC22B, SMPD1, TMEM9, NAPG, TMEM9B, GPRC5B, B4GALT5, TMEM171, ASPH, SLC39A4, VPS45, SNAP29, HLA-C, STX11, STX18,

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
VTI1A
HDAC1

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs to VTI1A-HDAC1

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to VTI1A-HDAC1

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	VTI1A	C0001418	Adenocarcinoma	1	CTD_human
Hgene	VTI1A	C0009402	Colorectal Carcinoma	1	CTD_human
Hgene	VTI1A	C0009404	Colorectal Neoplasms	1	CTD_human
Hgene	VTI1A	C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Hgene	VTI1A	C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Hgene	VTI1A	C0205643	Carcinoma, Cribriform	1	CTD_human
Hgene	VTI1A	C0205644	Carcinoma, Granular Cell	1	CTD_human
Hgene	VTI1A	C0205645	Adenocarcinoma, Tubular	1	CTD_human