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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: EIF3M (NCBI Gene ID:10480)

Gene Summary

Gene Summary

Gene Information	Gene Name: EIF3M
	Gene ID: 10480
	Gene Symbol	EIF3M
	Gene ID	10480
	Gene Name	eukaryotic translation initiation factor 3 subunit M
	Synonyms	B5\|GA17\|PCID1\|TANGO7\|hfl-B5
	Cytomap	11p13
	Type of Gene	protein-coding
	Description	eukaryotic translation initiation factor 3 subunit MB5 receptorPCI domain containing 1 (herpesvirus entry mediator)PCI domain-containing protein 1dendritic cell proteinfetal lung protein B5transport and golgi organization 7 homolog
	Modification date	20200313
	UniProtAcc	Q7L2H7

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0008135	Translation factor activity, RNA binding
GO:0002181	Cytoplasmic translation
GO:0006413	Translational initiation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
EIF3M	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'EIF3M[title] AND translation [title] AND human.'

Gene	Title	PMID
EIF3M	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000531120	32608557	32608690	Frame-shift
ENST00000531120	32610557	32610681	Frame-shift
ENST00000531120	32616459	32616559	Frame-shift
ENST00000531120	32617511	32617593	Frame-shift
ENST00000531120	32623307	32623368	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUAD	EIF3M	-1.5429573968308	4.40678669801292e-06
KIRC	EIF3M	-2.00888134658998	8.07326657761222e-05

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type

Gene

Coefficient

Pvalue

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with EIF3M (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	EIF3M	MIF	0.801654585	7.59E-12
DLBC	Cell metabolism gene	EIF3M	ATP5G1	0.802238059	7.14E-12
DLBC	Cell metabolism gene	EIF3M	SNRPB	0.80976611	3.19E-12
DLBC	Cell metabolism gene	EIF3M	SNRPD3	0.819456109	1.07E-12
DLBC	Cell metabolism gene	EIF3M	TOMM22	0.823330679	6.81E-13
DLBC	Cell metabolism gene	EIF3M	PSMC3	0.825304732	5.38E-13
DLBC	Cell metabolism gene	EIF3M	TIMM9	0.827014667	4.37E-13
DLBC	Cell metabolism gene	EIF3M	SNRPD2	0.827996972	3.88E-13
DLBC	Cell metabolism gene	EIF3M	POLR2F	0.829004593	3.43E-13
DLBC	Cell metabolism gene	EIF3M	TIMM8B	0.830346932	2.90E-13
DLBC	Cell metabolism gene	EIF3M	TIMM13	0.835386466	1.54E-13
DLBC	Cell metabolism gene	EIF3M	FAU	0.837472912	1.17E-13
DLBC	Cell metabolism gene	EIF3M	PFDN4	0.840161875	8.25E-14
DLBC	Cell metabolism gene	EIF3M	PSMD13	0.843768521	5.09E-14
DLBC	Cell metabolism gene	EIF3M	PTDSS2	0.845835998	3.83E-14
DLBC	Cell metabolism gene	EIF3M	POLR2L	0.855070963	1.03E-14
DLBC	Cell metabolism gene	EIF3M	TIMM10	0.855454822	9.71E-15
DLBC	Cell metabolism gene	EIF3M	NME2	0.877217357	2.91E-16
DLBC	CGC	EIF3M	HRAS	0.858731258	5.95E-15
DLBC	Epifactor	EIF3M	RRP8	0.802346016	7.06E-12
DLBC	Epifactor	EIF3M	BRMS1	0.806586713	4.51E-12
DLBC	Epifactor	EIF3M	FBL	0.822397008	7.60E-13
DLBC	IUPHAR	EIF3M	SLC25A3	0.801036516	8.10E-12
DLBC	IUPHAR	EIF3M	HRAS	0.858731258	5.95E-15
DLBC	TF	EIF3M	THAP4	0.813954723	2.01E-12
DLBC	TF	EIF3M	NME2	0.877217357	2.91E-16
DLBC	TSG	EIF3M	PHB	0.803150538	6.49E-12
DLBC	TSG	EIF3M	BRMS1	0.806586713	4.51E-12
DLBC	TSG	EIF3M	GADD45GIP1	0.827611383	4.07E-13
PRAD	Cell metabolism gene	EIF3M	TIMM9	0.824670691	9.92E-138
TGCT	Cell metabolism gene	EIF3M	SNRPD1	0.828043665	1.54E-40
THYM	Cell metabolism gene	EIF3M	NUDT5	0.801229542	1.55E-28
THYM	IUPHAR	EIF3M	CSNK2B	0.829035104	4.46E-32
UCS	Cell metabolism gene	EIF3M	NUDT5	0.801229542	1.55E-28
UCS	IUPHAR	EIF3M	CSNK2B	0.829035104	4.46E-32
UVM	Cell metabolism gene	EIF3M	TIMM9	0.838255662	3.06E-22
UVM	TSG	EIF3M	RBMX	0.803547984	2.97E-19

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
COAD	EIF3M	EIF3K	-1.81556046390697	0.000109195709228516
KICH	EIF3M	EIF3I	1.57310069220802	0.000139892101287842
LUAD	EIF3M	EIF3D	-2.4724631441106	0.000299564272708473
LUAD	EIF3M	EIF3CL	-2.13616202681733	0.000327584192623451
PRAD	EIF3M	EIF3A	1.13680328391952	0.000363360004697762
LIHC	EIF3M	EIF3C	-1.23074521883972	0.00126327311470459
BRCA	EIF3M	EIF3I	-1.72233459275531	0.00191218761269043
LUAD	EIF3M	EIF3J	-1.1109238877878	0.00216965225011196
KIRP	EIF3M	EIF3G	-2.4178322962129	0.00471024587750435
BLCA	EIF3M	EIF3A	-4.45104058307747	0.00532913208007812
LIHC	EIF3M	EIF3E	-5.1722332599854	0.00593802028362182
LUSC	EIF3M	EIF3CL	-1.65891070592699	0.00704157337736851
BRCA	EIF3M	EIF3CL	-1.45129115344564	0.0202464785451748
KICH	EIF3M	EIF3D	-5.64942867023017	0.0202749371528625
HNSC	EIF3M	EIF3CL	-1.69346209598213	0.028266192551655
UCEC	EIF3M	EIF3G	-3.35078334696571	0.03125
BLCA	EIF3M	EIF3G	-3.07707559649091	0.0323410034179688
LUAD	EIF3M	EIF3B	-5.80435587546762	1.0542655358657e-09
KIRC	EIF3M	EIF3D	-2.33501876832058	1.16831478033445e-08
THCA	EIF3M	EIF3J	1.32428508175103	1.19078203681914e-07
BRCA	EIF3M	EIF3G	1.87948385011271	1.9107949115022e-06
KIRC	EIF3M	EIF3B	-1.56313263784517	2.35252849767166e-12
LIHC	EIF3M	EIF3D	-2.51854304632799	2.35319665208461e-06
KICH	EIF3M	EIF3J	2.09716749126717	3.19480895996094e-05
STAD	EIF3M	EIF3B	-4.7724660972007	3.25962901115418e-08
HNSC	EIF3M	EIF3B	2.6202554263604	4.48234413852334e-06
KIRP	EIF3M	EIF3B	-2.7592297042974	4.6566128730774e-09
BRCA	EIF3M	EIF3A	-1.218215573148	7.39403582934137e-06
KIRC	EIF3M	EIF3E	-4.49824101219462	7.8509870430991e-09
BRCA	EIF3M	EIF3E	-1.48408348062463	9.51829316317813e-08

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with EIF3M

EIF1B, EIF4A2, EIF3A, EIF3F, EIF3H, TADA2A, Eif3a, EIF3B, APP, EIF3C, EIF3E, EIF3D, EIF3I, EIF3K, EIF3L, EIF3G, gag-pol, MMS19, NPM1, EXOSC10, SRPK1, rev, FAM96B, HUWE1, EGFR, EIF3CL, USP34, HSPB1, AHCYL1, COPS4, RPN1, EIF3J, NTRK1, MED4, HERC2, Eif3e, Eif3i, Rpl35, NF2, PTP4A1, PSMD12, EIF4A1, GPBP1L1, UBE2N, CYLD, DLD, TRIM25, G3BP1, BRCA1, HNRNPL, CFTR, PSMD1, VPS72, ZNF598, RMND5A, PRPF8, EFTUD2, ESR2, HEXIM1, MEPCE, LARP7, RECQL4, ELAVL1, KCNJ2, ZFP36L2, MYC, TP53, KIAA1429, EIF4B, ATG16L1, TGFBR2, METTL3, USP14, NR2C2, GBF1, CD74, DDX60, RAB27A, BIRC3, WWP2, nsp2ab, CMTR1, ZMYND10, ABI3, TRIML2, ZNF783, CUL7, PLEKHA4, MIB1, DOK2, RAB5A, nsp1, nsp7, ESR1, CIT, ANLN, CHMP4C, ECT2, ACACA, BRD4, Apc2, BKRF1, EIF4E, ANGEL1, EIF4G3, EIF4EBP2, EIF4ENIF1, EIF4EBP1, EIF4G1, UBQLN1, FZR1, WDR5, PSD4, PNMA2, GSTA5, EP300, FBXO32, OPTN, SLFN11,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
EIF3M	STAD	chr11	32610588	32610588	G	C	Missense_Mutation	p.K115N	4
EIF3M	KIRP	chr11	32623898	32623898	A	T	Missense_Mutation	p.N360Y	4
EIF3M	LIHC	chr11	32610663	32610663	C	-	Frame_Shift_Del	p.I140fs	3
EIF3M	COAD	chr11	32611130	32611130	A	-	Frame_Shift_Del	p.E159fs	3
EIF3M	LIHC	chr11	32616533	32616533	T	-	Frame_Shift_Del	p.F231fs	3
EIF3M	HNSC	chr11	32615476	32615476	G	T	Missense_Mutation	p.A200S	3
EIF3M	BRCA	chr11	32608625	32608625	G	C	Missense_Mutation	p.G37A	3
EIF3M	UCEC	chr11	32615480	32615480	G	A	Missense_Mutation	p.R201Q	3
EIF3M	GBM	chr11	32615446	32615446	G	A	Missense_Mutation	p.G190R	3
EIF3M	UCEC	chr11	32611116	32611116	G	T	Missense_Mutation	p.W154C	3
EIF3M	BLCA	chr11	32622318	32622318	G	C	Missense_Mutation	p.D295H	2
EIF3M	STAD	chr11	32610169	32610169	T	A	Missense_Mutation	p.S69T	2
EIF3M	UCEC	chr11	32605475	32605475	G	T	Missense_Mutation	p.Q14H	2
EIF3M	STAD	chr11	32623875	32623875	A	G	Missense_Mutation	p.D352G	2
EIF3M	UCEC	chr11	32608616	32608616	C	T	Missense_Mutation	p.S34L	2
EIF3M	STAD	chr11	32615494	32615494	A	G	Missense_Mutation	p.R206G	2
EIF3M	UCEC	chr11	32617542	32617542	G	A	Missense_Mutation	p.A250T	2
EIF3M	STAD	chr11	32616545	32616545	G	A	Missense_Mutation	p.E235K	2
EIF3M	LIHC	chr11	32623334	32623334	A	-	Frame_Shift_Del	p.K324fs	2
EIF3M	UCEC	chr11	32622234	32622234	G	T	Splice_Site	e9-1	2
EIF3M	HNSC	chr11	32615458	32615458	G	C	Missense_Mutation	p.E194Q	2
EIF3M	LIHC	chr11	32623354	32623354	A	-	Frame_Shift_Del	p.R330fs	2
EIF3M	UCEC	chr11	32622308	32622308	A	C	Missense_Mutation	p.E291D	2
EIF3M	KIRC	chr11	32610272	32610272	T	C	Missense_Mutation	p.L103P	2
EIF3M	UCEC	chr11	32622377	32622377	C	T	Silent	p.D314	2
EIF3M	CESC	chr11	32610234	32610234	G	A	Silent		2
EIF3M	BLCA	chr11	32610646	32610646	G	A	Missense_Mutation	p.G135R	2
EIF3M	LIHC	chr11	32610277	32610277	T	C	Silent		2
EIF3M	GBM	chr11	32610174	32610174	A	G	Silent		1
EIF3M	SKCM	chr11	32610244	32610244	C	T	Missense_Mutation	p.R94C	1
EIF3M	UCEC	chr11	32622234	32622234	G	T	Splice_Site	p.G267_splice	1
EIF3M	COAD	chr11	32610208	32610208	T	A	Missense_Mutation	p.L82M	1
EIF3M	OV	chr11	32608572	32608572	T	G	Silent	p.R19R	1
EIF3M	GBM	chr11	32615446	32615446	G	A	Missense_Mutation		1
EIF3M	BLCA	chr11	32605464	32605464	G	A	Missense_Mutation	p.E11K	1
EIF3M	LIHC	chr11	32610226	32610227	-	A	Frame_Shift_Ins	p.K88fs	1
EIF3M	COAD	chr11	32610209	32610209	T	A	Nonsense_Mutation	p.L82X	1
EIF3M	PAAD	chr11	32610244	32610244	C	A	Missense_Mutation		1
EIF3M	HNSC	chr11	32615458	32615458	G	C	Missense_Mutation		1
EIF3M	BLCA	chr11	32615485	32615485	G	C	Missense_Mutation	p.D203H	1
EIF3M	LIHC	chr11	32610240	32610241	-	T	Frame_Shift_Ins	p.S93fs	1
EIF3M	PRAD	chr11	32610621	32610621	C	T	Silent	p.S126S	1
EIF3M	HNSC	chr11	32615476	32615476	G	T	Missense_Mutation		1
EIF3M	BLCA	chr11	32608636	32608636	G	A	Missense_Mutation	p.D41N	1
EIF3M	COAD	chr11	32615495	32615495	G	T	Missense_Mutation	p.R206M	1
EIF3M	SARC	chr11	32605438	32605438	G	T	Missense_Mutation		1
EIF3M	BLCA	chr11	32610646	32610646	G	A	Missense_Mutation		1
EIF3M	BLCA	chr11	32615424	32615424	A	G	Silent	p.S182S	1
EIF3M	DLBC	chr11	32622233	32622233	A	T	Splice_Site	.	1
EIF3M	SARC	chr11	32610205	32610205	G	T	Missense_Mutation		1
EIF3M	BLCA	chr11	32622318	32622318	G	C	Missense_Mutation		1
EIF3M	THCA	chr11	32611145	32611145	T	C	Missense_Mutation		1
EIF3M	BLCA	chr11	32608657	32608657	G	T	Missense_Mutation	p.A48S	1
EIF3M	DLBC	chr11	32610617	32610617	G	T	Missense_Mutation	p.C125F	1
EIF3M	SARC	chr11	32610620	32610620	G	T	Missense_Mutation		1
EIF3M	BLCA	chr11	32605464	32605464	G	A	Missense_Mutation		1
EIF3M	THCA	chr11	32611145	32611145	T	C	Missense_Mutation	p.L164P	1
EIF3M	LIHC	chr11	32608638	32608638	T	-	Frame_Shift_Del	p.D41fs	1
EIF3M	ESCA	chr11	32622329	32622329	G	T	Missense_Mutation		1
EIF3M	SARC	chr11	32622348	32622348	G	T	Missense_Mutation		1
EIF3M	BLCA	chr11	32615485	32615485	G	C	Missense_Mutation		1
EIF3M	THYM	chr11	32608617	32608617	G	T	Silent	p.S34S	1
EIF3M	LUAD	chr11	32610279	32610279	G	A	Splice_Site		1
EIF3M	ESCA	chr11	32616545	32616545	G	T	Nonsense_Mutation	p.E235X	1
EIF3M	SARC	chr11	32610620	32610620	G	T	Missense_Mutation	p.S126I	1
EIF3M	BLCA	chr11	32608636	32608636	G	A	Missense_Mutation		1
EIF3M	KIRP	chr11	32623898	32623898	A	T	Missense_Mutation		1
EIF3M	UCEC	chr11	32611144	32611144	C	A	Missense_Mutation	p.L164I	1
EIF3M	CESC	chr11	32610664	32610664	C	A	Missense_Mutation		1
EIF3M	LUAD	chr11	32622378	32622378	G	T	Splice_Site	p.A315_splice	1
EIF3M	ESCA	chr11	32622329	32622329	G	T	Missense_Mutation	p.Q298H	1
EIF3M	SARC	chr11	32605438	32605438	G	T	Missense_Mutation	p.S2I	1
EIF3M	BLCA	chr11	32605455	32605455	G	T	Missense_Mutation		1
EIF3M	LIHC	chr11	32610571	32610571	T	C	Missense_Mutation		1
EIF3M	CESC	chr11	32610234	32610234	G	A	Silent	p.L90	1
EIF3M	LUAD	chr11	32610279	32610279	G	A	Splice_Site	p.L105_splice	1
EIF3M	SKCM	chr11	32610214	32610214	G	A	Missense_Mutation	p.E84K	1
EIF3M	COAD	chr11	32610207	32610207	T	A	Silent	p.A81A	1
EIF3M	LUSC	chr11	32616471	32616471	G	T	Missense_Mutation	p.R210L	1

Copy number variation (CNV) of EIF3M
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across EIF3M
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
96910	PRAD	TCGA-G9-6348-01A	ATP6AP2	chrX	40465889	-	EIF3M	chr11	32611132	+
96910	N/A	FN096427	CCDC73	chr11	32623828	-	EIF3M	chr11	32623846	-
103100	N/A	NM_006360	EIF3M	chr11	32623368	+	CCDC73	chr11	32623825	+
45813	OV	TCGA-57-1993-01A	EIF3M	chr11	32605475	+	CSTF3	chr11	33163532	-
96910	N/A	BQ428530	EIF3M	chr11	32611166	-	EIF3M	chr11	32616460	+
96910	N/A	CA312302	EIF3M	chr11	32623319	-	EIF3M	chr11	32617512	+
65787	STAD	TCGA-IN-A7NT	EIF3M	chr11	32605475	+	FAM118A	chr22	45726483	+
94802	N/A	BG002942	EIF3M	chr11	32616166	-	KRT7	chr12	52637084	-
102197	N/A	AF277183	EIF3M	chr11	32624019	+	NLRP5	chr19	56523928	+
102982	N/A	BP428638	EIF3M	chr11	32608616	+	PPIE	chr1	40219177	+
101351	N/A	BC019360	EIF3M	chr11	32605399	-	SYNCRIP	chr6	86352608	-
101258	SARC	TCGA-DX-A1KU-01A	EIF3M	chr11	32617593	+	UEVLD	chr11	18591924	-
96910	HNSC	TCGA-CQ-A4C9-01A	ELP4	chr11	31671769	+	EIF3M	chr11	32616460	+
96910	BRCA	TCGA-C8-A12V-01A	PDHX	chr11	34979130	+	EIF3M	chr11	32622235	+
96910	BRCA	TCGA-E2-A573-01A	PNN	chr14	39645353	+	EIF3M	chr11	32616460	+
96910	CESC	TCGA-WL-A834-01A	PRRG4	chr11	32860476	+	EIF3M	chr11	32622235	+
96910	CESC	TCGA-WL-A834-01A	PRRG4	chr11	32861785	+	EIF3M	chr11	32622235	+
96910	OV	TCGA-04-1350	RPL5	chr1	93297674	+	EIF3M	chr11	32616459	+
96910	N/A	BF753104	SSRP1	chr11	57099366	+	EIF3M	chr11	32610231	+
96914	PRAD	TCGA-EJ-5494-01A	UPF1	chr19	18979038	-	EIF3M	chr11	32611132	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	EIF3M	0.0187131007146727	0.51
THCA	EIF3M	0.0369211887056317	0.96
BLCA	EIF3M	0.0471743935565358	1
KIRC	EIF3M	2.35218640964699e-05	0.00066

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	EIF3M	0.0447828710088935	1
THCA	EIF3M	0.0419924916540688	1
PAAD	EIF3M	0.0331219861085606	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source