*UTHEALTH HOME *ABOUT SBMI *DIRECTORY *A-Z *WEBMAIL *INSIDE THE UNIVERSITY |
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Representative human translation factors from wikipathways and previous papersInitiation40S subunit: EIF3S1 (EIF3J), EIF3S2 (EIF3I), EIF3S3 (EIF3H), EIF3S4 (EIF3G), EIF3S5 (EIF3F), EIF3S6 (EIF3E), EIF3S7 (EIF3D), EIF3S8 (EIF3C), EIF3S9 (EIF3B), EIF3S10 (EIF3A) 43S pre-initiation complex: 40S + EIF1AX, EIF1AY, EIF5B + EIF2S1, EIF2S2, EIF2S3 (|-- EIF2AK1, EIF2AK2, EIF2AK3) (<-- EIF2B1, EIF2B2, EIF2B3, EIF2B4) EIF4E: recruitment of 43S to m7G (|-- EIF4EBP1, EIF4EBP2, EIF4EBP3) Scanning to AUG: 43s + SUI1 + EIF4A1, EIF4A2, EIF4B, WBSCR1 ITGB4BP: recruitment of 60S subunit and first peptide bond 60S’s EIF5, EIF5A: bind to AUG Elongation EEF1A1, EEF1A2, EEF1B2, EEF1G, EEF1D: binds to aminoacyl-tRNA Termination ETF1, GSPT1, GSPT2: releasing factors |
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