Home

Download

Statistics

Examples

Help

Contact

	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPL28 (NCBI Gene ID:10573)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPL28
	Gene ID: 10573
	Gene Symbol	MRPL28
	Gene ID	10573
	Gene Name	mitochondrial ribosomal protein L28
	Synonyms	MAAT1\|p15
	Cytomap	16p13.3
	Type of Gene	protein-coding
	Description	39S ribosomal protein L28, mitochondrialL28mtMRP-L28melanoma antigen p15melanoma-associated antigen recognised by cytotoxic T lymphocytesmelanoma-associated antigen recognized by T-lymphocytesmitochondrial large ribosomal subunit protein bL28m
	Modification date	20200313
	UniProtAcc	Q13084

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

Top

Translation Studies in PubMed

We searched PubMed using 'MRPL28[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPL28	.	.

Top

Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

Top

Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KIRP	MRPL28	1.10848699852281	0.00779616041108966
LUSC	MRPL28	-2.17870242177449	1.51941378521463e-05
LUAD	MRPL28	-1.41031503837636	5.67286357063566e-05

Top

Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
LUSC	MRPL28	1	2	0.039019780254905	0.16474	0.363190259259259	1.12202554638677	0.795047020744981
OV	MRPL28	1	2	0.0176925228565199	0.16396	0.321076585365854	0.193606563754577	0.357421512613861
SKCM	MRPL28	1	2	0.014468910357759	0.178257692307692	0.398856820776256	0.538617854077477	0.223845023027046
SKCM	MRPL28	3	1	0.0213357116288478	0.6474515	0.178257692307692	0.181077854077256	0.538617854077477

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
MESO	MRPL28	0.058274925	0.040660987
UCEC	MRPL28	0.097518604	0.040745705

Top

Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPL28 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
BRCA	Cell metabolism gene	MRPL28	GFER	0.805733238	6.99E-279
BRCA	CGC	MRPL28	NTHL1	0.84369447	0
BRCA	TF	MRPL28	ZNF205	0.815163514	1.19E-290
BRCA	TSG	MRPL28	STUB1	0.869840283	0
CESC	TSG	MRPL28	STUB1	0.804996787	2.34E-71
CHOL	TSG	MRPL28	GADD45GIP1	0.808361667	1.88E-11
CHOL	TSG	MRPL28	STUB1	0.837895443	7.06E-13
DLBC	Cell metabolism gene	MRPL28	TBCB	0.80056288	8.51E-12
DLBC	Cell metabolism gene	MRPL28	TALDO1	0.80174114	7.53E-12
DLBC	Cell metabolism gene	MRPL28	PSMB1	0.802402265	7.02E-12
DLBC	Cell metabolism gene	MRPL28	PIGQ	0.807771222	3.97E-12
DLBC	Cell metabolism gene	MRPL28	TIMM9	0.80909833	3.43E-12
DLBC	Cell metabolism gene	MRPL28	HSD17B10	0.809829935	3.17E-12
DLBC	Cell metabolism gene	MRPL28	TPI1	0.81184224	2.54E-12
DLBC	Cell metabolism gene	MRPL28	SNRPB	0.812190317	2.44E-12
DLBC	Cell metabolism gene	MRPL28	SAMM50	0.812407134	2.39E-12
DLBC	Cell metabolism gene	MRPL28	GEMIN7	0.812862369	2.27E-12
DLBC	Cell metabolism gene	MRPL28	PFDN4	0.814339599	1.92E-12
DLBC	Cell metabolism gene	MRPL28	PSMA7	0.815715192	1.65E-12
DLBC	Cell metabolism gene	MRPL28	DTYMK	0.816513515	1.50E-12
DLBC	Cell metabolism gene	MRPL28	SAT2	0.817072012	1.41E-12
DLBC	Cell metabolism gene	MRPL28	DGUOK	0.819058953	1.12E-12
DLBC	Cell metabolism gene	MRPL28	ECHS1	0.819249436	1.10E-12
DLBC	Cell metabolism gene	MRPL28	POLR2J	0.821579181	8.37E-13
DLBC	Cell metabolism gene	MRPL28	SNRPD3	0.825970754	4.96E-13
DLBC	Cell metabolism gene	MRPL28	PGLS	0.82649863	4.66E-13
DLBC	Cell metabolism gene	MRPL28	PHKG2	0.829389175	3.27E-13
DLBC	Cell metabolism gene	MRPL28	B3GAT3	0.829988398	3.04E-13
DLBC	Cell metabolism gene	MRPL28	MED27	0.83142475	2.54E-13
DLBC	Cell metabolism gene	MRPL28	PTDSS2	0.833364769	1.99E-13
DLBC	Cell metabolism gene	MRPL28	PSMB10	0.840304891	8.10E-14
DLBC	Cell metabolism gene	MRPL28	PMVK	0.841799108	6.63E-14
DLBC	Cell metabolism gene	MRPL28	ITPA	0.842508864	6.03E-14
DLBC	Cell metabolism gene	MRPL28	GUK1	0.84256317	5.99E-14
DLBC	Cell metabolism gene	MRPL28	MIF	0.844326954	4.71E-14
DLBC	Cell metabolism gene	MRPL28	PFDN5	0.845556114	3.98E-14
DLBC	Cell metabolism gene	MRPL28	TIMM8B	0.846517681	3.49E-14
DLBC	Cell metabolism gene	MRPL28	PSMB4	0.847996259	2.84E-14
DLBC	Cell metabolism gene	MRPL28	NME2	0.848476441	2.65E-14
DLBC	Cell metabolism gene	MRPL28	PGP	0.850289849	2.05E-14
DLBC	Cell metabolism gene	MRPL28	UROD	0.85430277	1.15E-14
DLBC	Cell metabolism gene	MRPL28	TOMM22	0.855793928	9.23E-15
DLBC	Cell metabolism gene	MRPL28	TIMM50	0.856095244	8.83E-15
DLBC	Cell metabolism gene	MRPL28	FAU	0.856665566	8.11E-15
DLBC	Cell metabolism gene	MRPL28	LYPLA2	0.857303114	7.37E-15
DLBC	Cell metabolism gene	MRPL28	ACOT8	0.857723347	6.92E-15
DLBC	Cell metabolism gene	MRPL28	PSMC1	0.859491002	5.30E-15
DLBC	Cell metabolism gene	MRPL28	PHPT1	0.860874525	4.29E-15
DLBC	Cell metabolism gene	MRPL28	PAFAH1B3	0.863252033	2.96E-15
DLBC	Cell metabolism gene	MRPL28	PSMD4	0.863578678	2.81E-15
DLBC	Cell metabolism gene	MRPL28	EXOSC4	0.865660229	2.02E-15
DLBC	Cell metabolism gene	MRPL28	DPM2	0.86590191	1.95E-15
DLBC	Cell metabolism gene	MRPL28	SNRPD2	0.872216306	6.88E-16
DLBC	Cell metabolism gene	MRPL28	LSM4	0.872783569	6.25E-16
DLBC	Cell metabolism gene	MRPL28	MTX1	0.872950726	6.08E-16
DLBC	Cell metabolism gene	MRPL28	POLR2F	0.874341108	4.79E-16
DLBC	Cell metabolism gene	MRPL28	POLR2L	0.8797844	1.84E-16
DLBC	Cell metabolism gene	MRPL28	POLE4	0.883284635	9.70E-17
DLBC	Cell metabolism gene	MRPL28	POLR2I	0.887440725	4.41E-17
DLBC	Cell metabolism gene	MRPL28	PSMB6	0.887668174	4.22E-17
DLBC	Cell metabolism gene	MRPL28	TIMM13	0.887753268	4.15E-17
DLBC	Cell metabolism gene	MRPL28	PSMC5	0.901070046	2.64E-18
DLBC	Cell metabolism gene	MRPL28	PSMC3	0.914150323	1.17E-19
DLBC	Cell metabolism gene	MRPL28	PSMD13	0.917382012	5.00E-20
DLBC	Cell metabolism gene	MRPL28	PSMB3	0.927957822	2.40E-21
DLBC	Cell metabolism gene	MRPL28	GFER	0.929495598	1.49E-21
DLBC	CGC	MRPL28	MAP2K2	0.804478036	5.64E-12
DLBC	CGC	MRPL28	COX6C	0.805319426	5.16E-12
DLBC	CGC	MRPL28	TFPT	0.844191411	4.80E-14
DLBC	CGC	MRPL28	NTHL1	0.853602437	1.27E-14
DLBC	CGC	MRPL28	HRAS	0.895621852	8.51E-18
DLBC	Epifactor	MRPL28	RUVBL2	0.807901953	3.91E-12
DLBC	Epifactor	MRPL28	FBL	0.82711066	4.32E-13
DLBC	Epifactor	MRPL28	PAF1	0.83102004	2.67E-13
DLBC	Epifactor	MRPL28	SIRT6	0.832048897	2.35E-13
DLBC	Epifactor	MRPL28	PPP4C	0.838750399	9.94E-14
DLBC	Epifactor	MRPL28	TFPT	0.844191411	4.80E-14
DLBC	Epifactor	MRPL28	PRPF31	0.857586618	7.07E-15
DLBC	Epifactor	MRPL28	DMAP1	0.859255198	5.49E-15
DLBC	Epifactor	MRPL28	TAF10	0.860758953	4.36E-15
DLBC	Epifactor	MRPL28	EXOSC4	0.865660229	2.02E-15
DLBC	Epifactor	MRPL28	ZNHIT1	0.867205771	1.58E-15
DLBC	Epifactor	MRPL28	MBD3	0.880928683	1.50E-16
DLBC	Epifactor	MRPL28	BRMS1	0.887558046	4.31E-17
DLBC	Epifactor	MRPL28	RBX1	0.905295624	1.01E-18
DLBC	IUPHAR	MRPL28	PSMB1	0.802402265	7.02E-12
DLBC	IUPHAR	MRPL28	SIRT3	0.8035602	6.22E-12
DLBC	IUPHAR	MRPL28	MAP2K2	0.804478036	5.64E-12
DLBC	IUPHAR	MRPL28	MFSD2B	0.822228569	7.76E-13
DLBC	IUPHAR	MRPL28	BIRC5	0.825823548	5.05E-13
DLBC	IUPHAR	MRPL28	PHKG2	0.829389175	3.27E-13
DLBC	IUPHAR	MRPL28	SIRT6	0.832048897	2.35E-13
DLBC	IUPHAR	MRPL28	SLC25A26	0.833129053	2.05E-13
DLBC	IUPHAR	MRPL28	PMVK	0.841799108	6.63E-14
DLBC	IUPHAR	MRPL28	MPDU1	0.847096682	3.22E-14
DLBC	IUPHAR	MRPL28	PSMB6	0.887668174	4.22E-17
DLBC	IUPHAR	MRPL28	HRAS	0.895621852	8.51E-18
DLBC	Kinase	MRPL28	MAP2K2	0.804478036	5.64E-12
DLBC	Kinase	MRPL28	PHKG2	0.829389175	3.27E-13
DLBC	TF	MRPL28	ZNF428	0.805594081	5.01E-12
DLBC	TF	MRPL28	ZNF444	0.823213551	6.90E-13
DLBC	TF	MRPL28	THAP4	0.834192117	1.79E-13
DLBC	TF	MRPL28	IRF3	0.840502794	7.89E-14
DLBC	TF	MRPL28	NME2	0.848476441	2.65E-14
DLBC	TF	MRPL28	THAP3	0.860685317	4.41E-15
DLBC	TF	MRPL28	PIN1	0.867914661	1.40E-15
DLBC	TF	MRPL28	MBD3	0.880928683	1.50E-16
DLBC	TF	MRPL28	THAP7	0.922806184	1.11E-20
DLBC	TSG	MRPL28	SIRT3	0.8035602	6.22E-12
DLBC	TSG	MRPL28	PARK7	0.822059507	7.91E-13
DLBC	TSG	MRPL28	PHB	0.827491899	4.13E-13
DLBC	TSG	MRPL28	SIRT6	0.832048897	2.35E-13
DLBC	TSG	MRPL28	IRF3	0.840502794	7.89E-14
DLBC	TSG	MRPL28	STUB1	0.853076837	1.38E-14
DLBC	TSG	MRPL28	PIN1	0.867914661	1.40E-15
DLBC	TSG	MRPL28	BRMS1	0.887558046	4.31E-17
DLBC	TSG	MRPL28	TSSC4	0.914123229	1.17E-19
DLBC	TSG	MRPL28	GADD45GIP1	0.938869163	6.19E-23
HNSC	TSG	MRPL28	STUB1	0.823115969	1.02E-140
KICH	Cell metabolism gene	MRPL28	PHKG2	0.815990081	6.73E-23
KICH	IUPHAR	MRPL28	PHKG2	0.815990081	6.73E-23
KICH	Kinase	MRPL28	PHKG2	0.815990081	6.73E-23
KIRP	Cell metabolism gene	MRPL28	MTX1	0.800375883	2.60E-73
KIRP	Cell metabolism gene	MRPL28	APRT	0.814670768	6.01E-78
KIRP	Cell metabolism gene	MRPL28	GFER	0.832503821	2.51E-84
KIRP	Epifactor	MRPL28	PPP4C	0.843181107	1.61E-88
KIRP	TSG	MRPL28	STUB1	0.870596815	6.73E-101
LAML	TSG	MRPL28	STUB1	0.839694998	3.30E-47
LGG	Cell metabolism gene	MRPL28	PSMB6	0.806579775	1.20E-122
LGG	IUPHAR	MRPL28	PSMB6	0.806579775	1.20E-122
LGG	TSG	MRPL28	STUB1	0.836188014	7.57E-140
LIHC	TSG	MRPL28	STUB1	0.850784768	1.06E-119
MESO	Cell metabolism gene	MRPL28	GFER	0.829830753	3.02E-23
MESO	Epifactor	MRPL28	PPP4C	0.855876708	4.58E-26
MESO	TSG	MRPL28	GADD45GIP1	0.800895371	1.26E-20
MESO	TSG	MRPL28	STUB1	0.827082948	5.61E-23
PAAD	TSG	MRPL28	STUB1	0.849573919	3.63E-52
PCPG	Cell metabolism gene	MRPL28	PGLS	0.832605146	2.38E-49
PCPG	Epifactor	MRPL28	PPP4C	0.81042125	7.91E-45
PRAD	Cell metabolism gene	MRPL28	PHKG2	0.800383075	7.12E-124
PRAD	Cell metabolism gene	MRPL28	GUK1	0.80207958	8.88E-125
PRAD	Cell metabolism gene	MRPL28	UROD	0.802957763	3.00E-125
PRAD	Cell metabolism gene	MRPL28	POLR2E	0.803861411	9.74E-126
PRAD	Cell metabolism gene	MRPL28	PSMC1	0.803925411	9.00E-126
PRAD	Cell metabolism gene	MRPL28	TIMM13	0.80511374	2.03E-126
PRAD	Cell metabolism gene	MRPL28	POLR2F	0.805699272	9.74E-127
PRAD	Cell metabolism gene	MRPL28	GPX1	0.80716287	1.53E-127
PRAD	Cell metabolism gene	MRPL28	FAU	0.808666262	2.25E-128
PRAD	Cell metabolism gene	MRPL28	HSD17B10	0.809273675	1.03E-128
PRAD	Cell metabolism gene	MRPL28	DPM3	0.812416344	1.74E-130
PRAD	Cell metabolism gene	MRPL28	PFDN5	0.81302924	7.78E-131
PRAD	Cell metabolism gene	MRPL28	IDH3G	0.813480538	4.29E-131
PRAD	Cell metabolism gene	MRPL28	LSM4	0.813609414	3.62E-131
PRAD	Cell metabolism gene	MRPL28	PTGES2	0.816509309	7.61E-133
PRAD	Cell metabolism gene	MRPL28	PSMB7	0.816872356	4.67E-133
PRAD	Cell metabolism gene	MRPL28	PPCDC	0.817109688	3.39E-133
PRAD	Cell metabolism gene	MRPL28	PIGQ	0.817434473	2.19E-133
PRAD	Cell metabolism gene	MRPL28	TIMM50	0.817474565	2.07E-133
PRAD	Cell metabolism gene	MRPL28	NME3	0.817774845	1.38E-133
PRAD	Cell metabolism gene	MRPL28	PSMD4	0.819783403	8.94E-135
PRAD	Cell metabolism gene	MRPL28	TIMM17B	0.823680867	4.00E-137
PRAD	Cell metabolism gene	MRPL28	PMVK	0.824282141	1.72E-137
PRAD	Cell metabolism gene	MRPL28	SNRPD2	0.824773872	8.57E-138
PRAD	Cell metabolism gene	MRPL28	GPX4	0.830239224	3.28E-141
PRAD	Cell metabolism gene	MRPL28	B4GALT7	0.834293028	7.95E-144
PRAD	Cell metabolism gene	MRPL28	PGLS	0.834519729	5.65E-144
PRAD	Cell metabolism gene	MRPL28	POLR2L	0.835725476	9.11E-145
PRAD	Cell metabolism gene	MRPL28	PHPT1	0.839430134	3.04E-147
PRAD	Cell metabolism gene	MRPL28	PSMC5	0.839680207	2.06E-147
PRAD	Cell metabolism gene	MRPL28	PSMC3	0.851220328	1.45E-155
PRAD	Cell metabolism gene	MRPL28	GFER	0.862241421	5.07E-164
PRAD	Cell metabolism gene	MRPL28	PSMB3	0.864271679	1.17E-165
PRAD	Cell metabolism gene	MRPL28	POLR2I	0.87069635	5.04E-171
PRAD	CGC	MRPL28	SDHAF2	0.813107528	7.01E-131
PRAD	CGC	MRPL28	MAP2K2	0.82485469	7.64E-138
PRAD	CGC	MRPL28	ASPSCR1	0.841556416	1.08E-148
PRAD	CGC	MRPL28	HRAS	0.850149074	8.87E-155
PRAD	Epifactor	MRPL28	RUVBL2	0.801754998	1.32E-124
PRAD	Epifactor	MRPL28	C17orf49	0.803530606	1.47E-125
PRAD	Epifactor	MRPL28	PPP4C	0.82229004	2.80E-136
PRAD	Epifactor	MRPL28	PRPF31	0.823615191	4.39E-137
PRAD	Epifactor	MRPL28	BRMS1	0.82450438	1.25E-137
PRAD	Epifactor	MRPL28	DMAP1	0.834361871	7.17E-144
PRAD	Epifactor	MRPL28	SIRT6	0.839200631	4.35E-147
PRAD	Epifactor	MRPL28	ZNHIT1	0.848785386	8.69E-154
PRAD	IUPHAR	MRPL28	PHKG2	0.800383075	7.12E-124
PRAD	IUPHAR	MRPL28	PTGES2	0.816509309	7.61E-133
PRAD	IUPHAR	MRPL28	PMVK	0.824282141	1.72E-137
PRAD	IUPHAR	MRPL28	MAP2K2	0.82485469	7.64E-138
PRAD	IUPHAR	MRPL28	CSNK2B	0.830526624	2.15E-141
PRAD	IUPHAR	MRPL28	SIRT6	0.839200631	4.35E-147
PRAD	IUPHAR	MRPL28	HRAS	0.850149074	8.87E-155
PRAD	Kinase	MRPL28	PHKG2	0.800383075	7.12E-124
PRAD	Kinase	MRPL28	MAP2K2	0.82485469	7.64E-138
PRAD	TF	MRPL28	ZNF428	0.811081294	9.94E-130
PRAD	TF	MRPL28	THAP7	0.824860229	7.58E-138
PRAD	TF	MRPL28	ZNF688	0.826678574	5.70E-139
PRAD	TF	MRPL28	THAP3	0.833054546	5.09E-143
PRAD	TSG	MRPL28	BRMS1	0.82450438	1.25E-137
PRAD	TSG	MRPL28	SIRT6	0.839200631	4.35E-147
PRAD	TSG	MRPL28	TSSC4	0.884502187	1.36E-183
PRAD	TSG	MRPL28	GADD45GIP1	0.885928211	5.57E-185
PRAD	TSG	MRPL28	STUB1	0.888891098	6.30E-188
TGCT	Cell metabolism gene	MRPL28	LYPLA2	0.813117169	5.08E-38
TGCT	Cell metabolism gene	MRPL28	GFER	0.849566434	1.25E-44
THCA	Cell metabolism gene	MRPL28	SNRPD2	0.800060493	1.36E-128
THCA	Cell metabolism gene	MRPL28	IDH3G	0.800186805	1.16E-128
THCA	Cell metabolism gene	MRPL28	UROD	0.803545062	1.57E-130
THCA	Cell metabolism gene	MRPL28	PSMC1	0.804012601	8.54E-131
THCA	Cell metabolism gene	MRPL28	DHRS4L2	0.812951421	5.76E-136
THCA	Cell metabolism gene	MRPL28	POLR2I	0.814009151	1.35E-136
THCA	Cell metabolism gene	MRPL28	PPCDC	0.81455969	6.32E-137
THCA	Cell metabolism gene	MRPL28	PSMB1	0.816654192	3.44E-138
THCA	Cell metabolism gene	MRPL28	TOMM40	0.816721177	3.13E-138
THCA	Cell metabolism gene	MRPL28	PSMB7	0.818951369	1.35E-139
THCA	Cell metabolism gene	MRPL28	NT5C	0.822190158	1.30E-141
THCA	Cell metabolism gene	MRPL28	POLR2J	0.829095629	4.75E-146
THCA	Cell metabolism gene	MRPL28	PHPT1	0.830140708	9.72E-147
THCA	Cell metabolism gene	MRPL28	TIMM13	0.830689371	4.21E-147
THCA	Cell metabolism gene	MRPL28	ITPA	0.831866372	6.91E-148
THCA	Cell metabolism gene	MRPL28	B4GALT7	0.8339882	2.57E-149
THCA	Cell metabolism gene	MRPL28	B3GAT3	0.835235161	3.63E-150
THCA	Cell metabolism gene	MRPL28	ACOT8	0.835457986	2.56E-150
THCA	Cell metabolism gene	MRPL28	POLR2L	0.839282657	5.65E-153
THCA	Cell metabolism gene	MRPL28	DPM3	0.846438104	3.91E-158
THCA	Cell metabolism gene	MRPL28	PSMD13	0.848012168	2.64E-159
THCA	Cell metabolism gene	MRPL28	MTX1	0.84953213	1.90E-160
THCA	Cell metabolism gene	MRPL28	PSMC5	0.86303546	3.42E-171
THCA	Cell metabolism gene	MRPL28	APRT	0.863658347	1.03E-171
THCA	Cell metabolism gene	MRPL28	PSMC3	0.865227213	4.80E-173
THCA	Cell metabolism gene	MRPL28	PSMB6	0.870624424	9.50E-178
THCA	Cell metabolism gene	MRPL28	PSMB3	0.884171999	1.49E-190
THCA	Cell metabolism gene	MRPL28	EXOSC4	0.890874884	1.70E-197
THCA	CGC	MRPL28	NTHL1	0.817889238	6.07E-139
THCA	CGC	MRPL28	HRAS	0.832668341	2.00E-148
THCA	CGC	MRPL28	TFPT	0.854614721	2.30E-164
THCA	CGC	MRPL28	ASPSCR1	0.867131672	1.11E-174
THCA	Epifactor	MRPL28	MBD3	0.800295516	1.01E-128
THCA	Epifactor	MRPL28	INO80E	0.804277205	6.06E-131
THCA	Epifactor	MRPL28	PRPF31	0.84004532	1.64E-153
THCA	Epifactor	MRPL28	TFPT	0.854614721	2.30E-164
THCA	Epifactor	MRPL28	RUVBL2	0.865534393	2.63E-173
THCA	Epifactor	MRPL28	BRMS1	0.888233771	1.05E-194
THCA	Epifactor	MRPL28	EXOSC4	0.890874884	1.70E-197
THCA	Epifactor	MRPL28	ZNHIT1	0.902428684	1.34E-210
THCA	IUPHAR	MRPL28	PSMB1	0.816654192	3.44E-138
THCA	IUPHAR	MRPL28	NT5C	0.822190158	1.30E-141
THCA	IUPHAR	MRPL28	HRAS	0.832668341	2.00E-148
THCA	IUPHAR	MRPL28	PSMB6	0.870624424	9.50E-178
THCA	Kinase	MRPL28	FASTK	0.826157775	3.88E-144
THCA	TF	MRPL28	MBD3	0.800295516	1.01E-128
THCA	TF	MRPL28	ZNF688	0.815000112	3.44E-137
THCA	TSG	MRPL28	AIP	0.801620809	1.86E-129
THCA	TSG	MRPL28	STUB1	0.83854419	1.86E-152
THCA	TSG	MRPL28	GADD45GIP1	0.865304722	4.13E-173
THCA	TSG	MRPL28	TSSC4	0.882447389	7.76E-189
THCA	TSG	MRPL28	BRMS1	0.888233771	1.05E-194
THYM	Cell metabolism gene	MRPL28	SEC61G	0.801277028	1.53E-28
THYM	Cell metabolism gene	MRPL28	ALG3	0.801347648	1.50E-28
THYM	Cell metabolism gene	MRPL28	DHRS4L2	0.80257463	1.08E-28
THYM	Cell metabolism gene	MRPL28	TIMM17B	0.802865269	9.96E-29
THYM	Cell metabolism gene	MRPL28	GEMIN7	0.803379498	8.66E-29
THYM	Cell metabolism gene	MRPL28	TIMM22	0.803933617	7.44E-29
THYM	Cell metabolism gene	MRPL28	SNRPD1	0.804501159	6.37E-29
THYM	Cell metabolism gene	MRPL28	HMBS	0.80482372	5.83E-29
THYM	Cell metabolism gene	MRPL28	PSME2	0.807745523	2.59E-29
THYM	Cell metabolism gene	MRPL28	WBSCR22	0.807990124	2.42E-29
THYM	Cell metabolism gene	MRPL28	DOHH	0.812827007	6.10E-30
THYM	Cell metabolism gene	MRPL28	HSD17B10	0.813175363	5.52E-30
THYM	Cell metabolism gene	MRPL28	PSMD9	0.81657082	2.05E-30
THYM	Cell metabolism gene	MRPL28	TBCB	0.817596444	1.51E-30
THYM	Cell metabolism gene	MRPL28	DTYMK	0.818223229	1.25E-30
THYM	Cell metabolism gene	MRPL28	SSR2	0.818990906	9.96E-31
THYM	Cell metabolism gene	MRPL28	B3GNTL1	0.820627049	6.09E-31
THYM	Cell metabolism gene	MRPL28	EBP	0.821521159	4.64E-31
THYM	Cell metabolism gene	MRPL28	SMPD2	0.821524563	4.63E-31
THYM	Cell metabolism gene	MRPL28	POLR2E	0.821755875	4.32E-31
THYM	Cell metabolism gene	MRPL28	POLD4	0.822818554	3.12E-31
THYM	Cell metabolism gene	MRPL28	MIF	0.824737455	1.73E-31
THYM	Cell metabolism gene	MRPL28	PHPT1	0.824865357	1.66E-31
THYM	Cell metabolism gene	MRPL28	PPCDC	0.826027175	1.15E-31
THYM	Cell metabolism gene	MRPL28	SNRPD3	0.826979296	8.56E-32
THYM	Cell metabolism gene	MRPL28	PSMD4	0.827951162	6.29E-32
THYM	Cell metabolism gene	MRPL28	GALK1	0.828484526	5.31E-32
THYM	Cell metabolism gene	MRPL28	HMOX2	0.831068094	2.32E-32
THYM	Cell metabolism gene	MRPL28	PSMC1	0.833482524	1.05E-32
THYM	Cell metabolism gene	MRPL28	UROS	0.836194502	4.29E-33
THYM	Cell metabolism gene	MRPL28	GMPPA	0.836703404	3.62E-33
THYM	Cell metabolism gene	MRPL28	POLR2F	0.837379813	2.88E-33
THYM	Cell metabolism gene	MRPL28	TALDO1	0.837400907	2.86E-33
THYM	Cell metabolism gene	MRPL28	MMAB	0.839605211	1.35E-33
THYM	Cell metabolism gene	MRPL28	LSM2	0.842085796	5.73E-34
THYM	Cell metabolism gene	MRPL28	TOMM40	0.842313739	5.30E-34
THYM	Cell metabolism gene	MRPL28	PIGU	0.842360681	5.21E-34
THYM	Cell metabolism gene	MRPL28	PSMB10	0.844041461	2.89E-34
THYM	Cell metabolism gene	MRPL28	IDH3G	0.845048484	2.02E-34
THYM	Cell metabolism gene	MRPL28	SLC25A11	0.846960011	1.02E-34
THYM	Cell metabolism gene	MRPL28	POLD2	0.846995384	1.01E-34
THYM	Cell metabolism gene	MRPL28	DGUOK	0.849760361	3.67E-35
THYM	Cell metabolism gene	MRPL28	ITPA	0.849766022	3.66E-35
THYM	Cell metabolism gene	MRPL28	PGP	0.850749102	2.55E-35
THYM	Cell metabolism gene	MRPL28	NT5C	0.853534486	8.98E-36
THYM	Cell metabolism gene	MRPL28	OAZ1	0.854270105	6.79E-36
THYM	Cell metabolism gene	MRPL28	PTGES2	0.858070152	1.57E-36
THYM	Cell metabolism gene	MRPL28	POLR2H	0.858835914	1.16E-36
THYM	Cell metabolism gene	MRPL28	PSMB6	0.85893991	1.11E-36
THYM	Cell metabolism gene	MRPL28	LSM4	0.858978668	1.10E-36
THYM	Cell metabolism gene	MRPL28	FPGS	0.861416145	4.15E-37
THYM	Cell metabolism gene	MRPL28	DPM3	0.862746266	2.43E-37
THYM	Cell metabolism gene	MRPL28	POLR2L	0.863369077	1.88E-37
THYM	Cell metabolism gene	MRPL28	PHKG2	0.864337693	1.27E-37
THYM	Cell metabolism gene	MRPL28	LCMT1	0.867214482	3.83E-38
THYM	Cell metabolism gene	MRPL28	MTX1	0.867383405	3.56E-38
THYM	Cell metabolism gene	MRPL28	PMPCA	0.869406075	1.51E-38
THYM	Cell metabolism gene	MRPL28	PIGQ	0.8717142	5.56E-39
THYM	Cell metabolism gene	MRPL28	GUK1	0.872592284	3.78E-39
THYM	Cell metabolism gene	MRPL28	UROD	0.87264713	3.69E-39
THYM	Cell metabolism gene	MRPL28	B3GAT3	0.873988903	2.04E-39
THYM	Cell metabolism gene	MRPL28	POLR2J	0.874932894	1.34E-39
THYM	Cell metabolism gene	MRPL28	TIMM10	0.874992368	1.30E-39
THYM	Cell metabolism gene	MRPL28	PSMC5	0.885623574	8.72E-42
THYM	Cell metabolism gene	MRPL28	PSMD13	0.89259407	2.48E-43
THYM	Cell metabolism gene	MRPL28	PSMB1	0.892886592	2.13E-43
THYM	Cell metabolism gene	MRPL28	SLC27A5	0.893447366	1.58E-43
THYM	Cell metabolism gene	MRPL28	MVD	0.898007903	1.32E-44
THYM	Cell metabolism gene	MRPL28	PGLS	0.898374778	1.07E-44
THYM	Cell metabolism gene	MRPL28	PFDN5	0.90260721	9.50E-46
THYM	Cell metabolism gene	MRPL28	POLR2I	0.905028939	2.26E-46
THYM	Cell metabolism gene	MRPL28	TIMM50	0.909344391	1.58E-47
THYM	Cell metabolism gene	MRPL28	SNRPD2	0.909886514	1.12E-47
THYM	Cell metabolism gene	MRPL28	GFER	0.910721275	6.58E-48
THYM	Cell metabolism gene	MRPL28	APRT	0.911233322	4.73E-48
THYM	Cell metabolism gene	MRPL28	ACOT8	0.912336187	2.31E-48
THYM	Cell metabolism gene	MRPL28	PSMB7	0.913046361	1.45E-48
THYM	Cell metabolism gene	MRPL28	PSMC3	0.915159392	3.53E-49
THYM	Cell metabolism gene	MRPL28	FAU	0.91713334	9.13E-50
THYM	Cell metabolism gene	MRPL28	TIMM8B	0.919198459	2.14E-50
THYM	Cell metabolism gene	MRPL28	EXOSC4	0.919677389	1.52E-50
THYM	Cell metabolism gene	MRPL28	PSMB3	0.920190322	1.05E-50
THYM	Cell metabolism gene	MRPL28	TIMM13	0.932996199	4.27E-55
THYM	Cell metabolism gene	MRPL28	DPM2	0.933536702	2.67E-55
THYM	CGC	MRPL28	MGMT	0.848366609	6.12E-35
THYM	CGC	MRPL28	SDHAF2	0.86479195	1.05E-37
THYM	CGC	MRPL28	MAP2K2	0.878645069	2.46E-40
THYM	CGC	MRPL28	TFPT	0.892352649	2.82E-43
THYM	CGC	MRPL28	ASPSCR1	0.895470365	5.32E-44
THYM	CGC	MRPL28	RBM10	0.895495223	5.25E-44
THYM	Epifactor	MRPL28	MCRS1	0.805813238	4.43E-29
THYM	Epifactor	MRPL28	LAS1L	0.808163228	2.30E-29
THYM	Epifactor	MRPL28	RRP8	0.812127867	7.47E-30
THYM	Epifactor	MRPL28	ZGPAT	0.820206418	6.91E-31
THYM	Epifactor	MRPL28	CXXC1	0.821254047	5.03E-31
THYM	Epifactor	MRPL28	PRMT1	0.843115616	4.00E-34
THYM	Epifactor	MRPL28	PAF1	0.846587281	1.16E-34
THYM	Epifactor	MRPL28	CCDC101	0.861059089	4.79E-37
THYM	Epifactor	MRPL28	FBL	0.865346126	8.35E-38
THYM	Epifactor	MRPL28	PELP1	0.874384081	1.71E-39
THYM	Epifactor	MRPL28	RUVBL2	0.876107652	7.87E-40
THYM	Epifactor	MRPL28	DMAP1	0.878171031	3.06E-40
THYM	Epifactor	MRPL28	NOC2L	0.883317966	2.69E-41
THYM	Epifactor	MRPL28	INO80E	0.885538056	9.10E-42
THYM	Epifactor	MRPL28	TFPT	0.892352649	2.82E-43
THYM	Epifactor	MRPL28	C17orf49	0.89439317	9.52E-44
THYM	Epifactor	MRPL28	ZNHIT1	0.905636675	1.56E-46
THYM	Epifactor	MRPL28	TAF10	0.907822268	4.10E-47
THYM	Epifactor	MRPL28	PPP4C	0.909198247	1.73E-47
THYM	Epifactor	MRPL28	BRMS1	0.912073375	2.74E-48
THYM	Epifactor	MRPL28	MBD3	0.916682795	1.25E-49
THYM	Epifactor	MRPL28	EXOSC4	0.919677389	1.52E-50
THYM	Epifactor	MRPL28	PRPF31	0.929579228	7.63E-54
THYM	Epifactor	MRPL28	SIRT6	0.93091951	2.51E-54
THYM	IUPHAR	MRPL28	ATG4B	0.806512784	3.65E-29
THYM	IUPHAR	MRPL28	SMPD2	0.821524563	4.63E-31
THYM	IUPHAR	MRPL28	HMOX2	0.831068094	2.32E-32
THYM	IUPHAR	MRPL28	PRMT1	0.843115616	4.00E-34
THYM	IUPHAR	MRPL28	SIRT3	0.843998514	2.93E-34
THYM	IUPHAR	MRPL28	EGLN2	0.84420431	2.73E-34
THYM	IUPHAR	MRPL28	ATP6V0B	0.846672908	1.13E-34
THYM	IUPHAR	MRPL28	SLC25A11	0.846960011	1.02E-34
THYM	IUPHAR	MRPL28	NT5C	0.853534486	8.98E-36
THYM	IUPHAR	MRPL28	MPDU1	0.856967523	2.41E-36
THYM	IUPHAR	MRPL28	PTGES2	0.858070152	1.57E-36
THYM	IUPHAR	MRPL28	PSMB6	0.85893991	1.11E-36
THYM	IUPHAR	MRPL28	MMP24	0.863295479	1.94E-37
THYM	IUPHAR	MRPL28	PHKG2	0.864337693	1.27E-37
THYM	IUPHAR	MRPL28	MAP2K2	0.878645069	2.46E-40
THYM	IUPHAR	MRPL28	PSMB1	0.892886592	2.13E-43
THYM	IUPHAR	MRPL28	SLC27A5	0.893447366	1.58E-43
THYM	IUPHAR	MRPL28	MVD	0.898007903	1.32E-44
THYM	IUPHAR	MRPL28	SIRT6	0.93091951	2.51E-54
THYM	Kinase	MRPL28	PHKG2	0.864337693	1.27E-37
THYM	Kinase	MRPL28	MAP2K2	0.878645069	2.46E-40
THYM	TF	MRPL28	THYN1	0.806052604	4.15E-29
THYM	TF	MRPL28	ZBTB48	0.80845285	2.12E-29
THYM	TF	MRPL28	ZGPAT	0.820206418	6.91E-31
THYM	TF	MRPL28	CXXC1	0.821254047	5.03E-31
THYM	TF	MRPL28	ZNF444	0.822299249	3.66E-31
THYM	TF	MRPL28	ZNF511	0.825122007	1.53E-31
THYM	TF	MRPL28	RBCK1	0.826582423	9.69E-32
THYM	TF	MRPL28	GLI4	0.829346469	4.03E-32
THYM	TF	MRPL28	ZNF581	0.832995042	1.24E-32
THYM	TF	MRPL28	E4F1	0.837210978	3.05E-33
THYM	TF	MRPL28	ZNF580	0.840517554	9.88E-34
THYM	TF	MRPL28	ZNF408	0.8432075	3.87E-34
THYM	TF	MRPL28	AKAP8L	0.843305144	3.74E-34
THYM	TF	MRPL28	CENPB	0.844978057	2.07E-34
THYM	TF	MRPL28	ZNF524	0.846563996	1.17E-34
THYM	TF	MRPL28	DRAP1	0.848056932	6.85E-35
THYM	TF	MRPL28	ZNF668	0.852617775	1.27E-35
THYM	TF	MRPL28	ZNF32	0.859266329	9.78E-37
THYM	TF	MRPL28	REXO4	0.861901533	3.42E-37
THYM	TF	MRPL28	THAP7	0.866335176	5.53E-38
THYM	TF	MRPL28	ZNF688	0.870101352	1.12E-38
THYM	TF	MRPL28	ZNF428	0.898810303	8.39E-45
THYM	TF	MRPL28	THAP3	0.913161824	1.34E-48
THYM	TF	MRPL28	MBD3	0.916682795	1.25E-49
THYM	TF	MRPL28	ZNF787	0.920848051	6.51E-51
THYM	TSG	MRPL28	AIP	0.803854775	7.60E-29
THYM	TSG	MRPL28	PFN1	0.803963227	7.38E-29
THYM	TSG	MRPL28	ZBTB48	0.80845285	2.12E-29
THYM	TSG	MRPL28	GLTSCR2	0.810538411	1.18E-29
THYM	TSG	MRPL28	HTRA2	0.820713117	5.93E-31
THYM	TSG	MRPL28	GNB2L1	0.822255657	3.71E-31
THYM	TSG	MRPL28	PYCARD	0.826550616	9.79E-32
THYM	TSG	MRPL28	STUB1	0.828832055	4.75E-32
THYM	TSG	MRPL28	TUSC2	0.830441273	2.84E-32
THYM	TSG	MRPL28	PHB	0.831522349	2.00E-32
THYM	TSG	MRPL28	ARMC5	0.833314834	1.11E-32
THYM	TSG	MRPL28	MAD1L1	0.834575022	7.36E-33
THYM	TSG	MRPL28	SIRT3	0.843998514	2.93E-34
THYM	TSG	MRPL28	PARK7	0.848603658	5.61E-35
THYM	TSG	MRPL28	ZNF668	0.852617775	1.27E-35
THYM	TSG	MRPL28	NPRL2	0.864343136	1.26E-37
THYM	TSG	MRPL28	GABARAP	0.866968026	4.24E-38
THYM	TSG	MRPL28	BRMS1	0.912073375	2.74E-48
THYM	TSG	MRPL28	GADD45GIP1	0.927365195	4.57E-53
THYM	TSG	MRPL28	SIRT6	0.93091951	2.51E-54
THYM	TSG	MRPL28	TSSC4	0.957935299	6.65E-67
UCEC	Cell metabolism gene	MRPL28	POLR2L	0.80093331	3.31E-46
UCEC	Cell metabolism gene	MRPL28	EXOSC4	0.80164997	2.40E-46
UCEC	Cell metabolism gene	MRPL28	GFER	0.837882491	3.20E-54
UCEC	CGC	MRPL28	NTHL1	0.809320122	7.18E-48
UCEC	Epifactor	MRPL28	BRMS1	0.80096854	3.26E-46
UCEC	Epifactor	MRPL28	EXOSC4	0.80164997	2.40E-46
UCEC	TSG	MRPL28	BRMS1	0.80096854	3.26E-46
UCEC	TSG	MRPL28	GADD45GIP1	0.814465151	6.22E-49
UCEC	TSG	MRPL28	STUB1	0.843628239	1.20E-55
UCS	Cell metabolism gene	MRPL28	SEC61G	0.801277028	1.53E-28
UCS	Cell metabolism gene	MRPL28	ALG3	0.801347648	1.50E-28
UCS	Cell metabolism gene	MRPL28	DHRS4L2	0.80257463	1.08E-28
UCS	Cell metabolism gene	MRPL28	TIMM17B	0.802865269	9.96E-29
UCS	Cell metabolism gene	MRPL28	GEMIN7	0.803379498	8.66E-29
UCS	Cell metabolism gene	MRPL28	TIMM22	0.803933617	7.44E-29
UCS	Cell metabolism gene	MRPL28	SNRPD1	0.804501159	6.37E-29
UCS	Cell metabolism gene	MRPL28	HMBS	0.80482372	5.83E-29
UCS	Cell metabolism gene	MRPL28	PSME2	0.807745523	2.59E-29
UCS	Cell metabolism gene	MRPL28	WBSCR22	0.807990124	2.42E-29
UCS	Cell metabolism gene	MRPL28	DOHH	0.812827007	6.10E-30
UCS	Cell metabolism gene	MRPL28	HSD17B10	0.813175363	5.52E-30
UCS	Cell metabolism gene	MRPL28	PSMD9	0.81657082	2.05E-30
UCS	Cell metabolism gene	MRPL28	TBCB	0.817596444	1.51E-30
UCS	Cell metabolism gene	MRPL28	DTYMK	0.818223229	1.25E-30
UCS	Cell metabolism gene	MRPL28	SSR2	0.818990906	9.96E-31
UCS	Cell metabolism gene	MRPL28	B3GNTL1	0.820627049	6.09E-31
UCS	Cell metabolism gene	MRPL28	EBP	0.821521159	4.64E-31
UCS	Cell metabolism gene	MRPL28	SMPD2	0.821524563	4.63E-31
UCS	Cell metabolism gene	MRPL28	POLR2E	0.821755875	4.32E-31
UCS	Cell metabolism gene	MRPL28	POLD4	0.822818554	3.12E-31
UCS	Cell metabolism gene	MRPL28	MIF	0.824737455	1.73E-31
UCS	Cell metabolism gene	MRPL28	PHPT1	0.824865357	1.66E-31
UCS	Cell metabolism gene	MRPL28	PPCDC	0.826027175	1.15E-31
UCS	Cell metabolism gene	MRPL28	SNRPD3	0.826979296	8.56E-32
UCS	Cell metabolism gene	MRPL28	PSMD4	0.827951162	6.29E-32
UCS	Cell metabolism gene	MRPL28	GALK1	0.828484526	5.31E-32
UCS	Cell metabolism gene	MRPL28	HMOX2	0.831068094	2.32E-32
UCS	Cell metabolism gene	MRPL28	PSMC1	0.833482524	1.05E-32
UCS	Cell metabolism gene	MRPL28	UROS	0.836194502	4.29E-33
UCS	Cell metabolism gene	MRPL28	GMPPA	0.836703404	3.62E-33
UCS	Cell metabolism gene	MRPL28	POLR2F	0.837379813	2.88E-33
UCS	Cell metabolism gene	MRPL28	TALDO1	0.837400907	2.86E-33
UCS	Cell metabolism gene	MRPL28	MMAB	0.839605211	1.35E-33
UCS	Cell metabolism gene	MRPL28	LSM2	0.842085796	5.73E-34
UCS	Cell metabolism gene	MRPL28	TOMM40	0.842313739	5.30E-34
UCS	Cell metabolism gene	MRPL28	PIGU	0.842360681	5.21E-34
UCS	Cell metabolism gene	MRPL28	PSMB10	0.844041461	2.89E-34
UCS	Cell metabolism gene	MRPL28	IDH3G	0.845048484	2.02E-34
UCS	Cell metabolism gene	MRPL28	SLC25A11	0.846960011	1.02E-34
UCS	Cell metabolism gene	MRPL28	POLD2	0.846995384	1.01E-34
UCS	Cell metabolism gene	MRPL28	DGUOK	0.849760361	3.67E-35
UCS	Cell metabolism gene	MRPL28	ITPA	0.849766022	3.66E-35
UCS	Cell metabolism gene	MRPL28	PGP	0.850749102	2.55E-35
UCS	Cell metabolism gene	MRPL28	NT5C	0.853534486	8.98E-36
UCS	Cell metabolism gene	MRPL28	OAZ1	0.854270105	6.79E-36
UCS	Cell metabolism gene	MRPL28	PTGES2	0.858070152	1.57E-36
UCS	Cell metabolism gene	MRPL28	POLR2H	0.858835914	1.16E-36
UCS	Cell metabolism gene	MRPL28	PSMB6	0.85893991	1.11E-36
UCS	Cell metabolism gene	MRPL28	LSM4	0.858978668	1.10E-36
UCS	Cell metabolism gene	MRPL28	FPGS	0.861416145	4.15E-37
UCS	Cell metabolism gene	MRPL28	DPM3	0.862746266	2.43E-37
UCS	Cell metabolism gene	MRPL28	POLR2L	0.863369077	1.88E-37
UCS	Cell metabolism gene	MRPL28	PHKG2	0.864337693	1.27E-37
UCS	Cell metabolism gene	MRPL28	LCMT1	0.867214482	3.83E-38
UCS	Cell metabolism gene	MRPL28	MTX1	0.867383405	3.56E-38
UCS	Cell metabolism gene	MRPL28	PMPCA	0.869406075	1.51E-38
UCS	Cell metabolism gene	MRPL28	PIGQ	0.8717142	5.56E-39
UCS	Cell metabolism gene	MRPL28	GUK1	0.872592284	3.78E-39
UCS	Cell metabolism gene	MRPL28	UROD	0.87264713	3.69E-39
UCS	Cell metabolism gene	MRPL28	B3GAT3	0.873988903	2.04E-39
UCS	Cell metabolism gene	MRPL28	POLR2J	0.874932894	1.34E-39
UCS	Cell metabolism gene	MRPL28	TIMM10	0.874992368	1.30E-39
UCS	Cell metabolism gene	MRPL28	PSMC5	0.885623574	8.72E-42
UCS	Cell metabolism gene	MRPL28	PSMD13	0.89259407	2.48E-43
UCS	Cell metabolism gene	MRPL28	PSMB1	0.892886592	2.13E-43
UCS	Cell metabolism gene	MRPL28	SLC27A5	0.893447366	1.58E-43
UCS	Cell metabolism gene	MRPL28	MVD	0.898007903	1.32E-44
UCS	Cell metabolism gene	MRPL28	PGLS	0.898374778	1.07E-44
UCS	Cell metabolism gene	MRPL28	PFDN5	0.90260721	9.50E-46
UCS	Cell metabolism gene	MRPL28	POLR2I	0.905028939	2.26E-46
UCS	Cell metabolism gene	MRPL28	TIMM50	0.909344391	1.58E-47
UCS	Cell metabolism gene	MRPL28	SNRPD2	0.909886514	1.12E-47
UCS	Cell metabolism gene	MRPL28	GFER	0.910721275	6.58E-48
UCS	Cell metabolism gene	MRPL28	APRT	0.911233322	4.73E-48
UCS	Cell metabolism gene	MRPL28	ACOT8	0.912336187	2.31E-48
UCS	Cell metabolism gene	MRPL28	PSMB7	0.913046361	1.45E-48
UCS	Cell metabolism gene	MRPL28	PSMC3	0.915159392	3.53E-49
UCS	Cell metabolism gene	MRPL28	FAU	0.91713334	9.13E-50
UCS	Cell metabolism gene	MRPL28	TIMM8B	0.919198459	2.14E-50
UCS	Cell metabolism gene	MRPL28	EXOSC4	0.919677389	1.52E-50
UCS	Cell metabolism gene	MRPL28	PSMB3	0.920190322	1.05E-50
UCS	Cell metabolism gene	MRPL28	TIMM13	0.932996199	4.27E-55
UCS	Cell metabolism gene	MRPL28	DPM2	0.933536702	2.67E-55
UCS	CGC	MRPL28	MGMT	0.848366609	6.12E-35
UCS	CGC	MRPL28	SDHAF2	0.86479195	1.05E-37
UCS	CGC	MRPL28	MAP2K2	0.878645069	2.46E-40
UCS	CGC	MRPL28	TFPT	0.892352649	2.82E-43
UCS	CGC	MRPL28	ASPSCR1	0.895470365	5.32E-44
UCS	CGC	MRPL28	RBM10	0.895495223	5.25E-44
UCS	Epifactor	MRPL28	MCRS1	0.805813238	4.43E-29
UCS	Epifactor	MRPL28	LAS1L	0.808163228	2.30E-29
UCS	Epifactor	MRPL28	RRP8	0.812127867	7.47E-30
UCS	Epifactor	MRPL28	ZGPAT	0.820206418	6.91E-31
UCS	Epifactor	MRPL28	CXXC1	0.821254047	5.03E-31
UCS	Epifactor	MRPL28	PRMT1	0.843115616	4.00E-34
UCS	Epifactor	MRPL28	PAF1	0.846587281	1.16E-34
UCS	Epifactor	MRPL28	CCDC101	0.861059089	4.79E-37
UCS	Epifactor	MRPL28	FBL	0.865346126	8.35E-38
UCS	Epifactor	MRPL28	PELP1	0.874384081	1.71E-39
UCS	Epifactor	MRPL28	RUVBL2	0.876107652	7.87E-40
UCS	Epifactor	MRPL28	DMAP1	0.878171031	3.06E-40
UCS	Epifactor	MRPL28	NOC2L	0.883317966	2.69E-41
UCS	Epifactor	MRPL28	INO80E	0.885538056	9.10E-42
UCS	Epifactor	MRPL28	TFPT	0.892352649	2.82E-43
UCS	Epifactor	MRPL28	C17orf49	0.89439317	9.52E-44
UCS	Epifactor	MRPL28	ZNHIT1	0.905636675	1.56E-46
UCS	Epifactor	MRPL28	TAF10	0.907822268	4.10E-47
UCS	Epifactor	MRPL28	PPP4C	0.909198247	1.73E-47
UCS	Epifactor	MRPL28	BRMS1	0.912073375	2.74E-48
UCS	Epifactor	MRPL28	MBD3	0.916682795	1.25E-49
UCS	Epifactor	MRPL28	EXOSC4	0.919677389	1.52E-50
UCS	Epifactor	MRPL28	PRPF31	0.929579228	7.63E-54
UCS	Epifactor	MRPL28	SIRT6	0.93091951	2.51E-54
UCS	IUPHAR	MRPL28	ATG4B	0.806512784	3.65E-29
UCS	IUPHAR	MRPL28	SMPD2	0.821524563	4.63E-31
UCS	IUPHAR	MRPL28	HMOX2	0.831068094	2.32E-32
UCS	IUPHAR	MRPL28	PRMT1	0.843115616	4.00E-34
UCS	IUPHAR	MRPL28	SIRT3	0.843998514	2.93E-34
UCS	IUPHAR	MRPL28	EGLN2	0.84420431	2.73E-34
UCS	IUPHAR	MRPL28	ATP6V0B	0.846672908	1.13E-34
UCS	IUPHAR	MRPL28	SLC25A11	0.846960011	1.02E-34
UCS	IUPHAR	MRPL28	NT5C	0.853534486	8.98E-36
UCS	IUPHAR	MRPL28	MPDU1	0.856967523	2.41E-36
UCS	IUPHAR	MRPL28	PTGES2	0.858070152	1.57E-36
UCS	IUPHAR	MRPL28	PSMB6	0.85893991	1.11E-36
UCS	IUPHAR	MRPL28	MMP24	0.863295479	1.94E-37
UCS	IUPHAR	MRPL28	PHKG2	0.864337693	1.27E-37
UCS	IUPHAR	MRPL28	MAP2K2	0.878645069	2.46E-40
UCS	IUPHAR	MRPL28	PSMB1	0.892886592	2.13E-43
UCS	IUPHAR	MRPL28	SLC27A5	0.893447366	1.58E-43
UCS	IUPHAR	MRPL28	MVD	0.898007903	1.32E-44
UCS	IUPHAR	MRPL28	SIRT6	0.93091951	2.51E-54
UCS	Kinase	MRPL28	PHKG2	0.864337693	1.27E-37
UCS	Kinase	MRPL28	MAP2K2	0.878645069	2.46E-40
UCS	TF	MRPL28	THYN1	0.806052604	4.15E-29
UCS	TF	MRPL28	ZBTB48	0.80845285	2.12E-29
UCS	TF	MRPL28	ZGPAT	0.820206418	6.91E-31
UCS	TF	MRPL28	CXXC1	0.821254047	5.03E-31
UCS	TF	MRPL28	ZNF444	0.822299249	3.66E-31
UCS	TF	MRPL28	ZNF511	0.825122007	1.53E-31
UCS	TF	MRPL28	RBCK1	0.826582423	9.69E-32
UCS	TF	MRPL28	GLI4	0.829346469	4.03E-32
UCS	TF	MRPL28	ZNF581	0.832995042	1.24E-32
UCS	TF	MRPL28	E4F1	0.837210978	3.05E-33
UCS	TF	MRPL28	ZNF580	0.840517554	9.88E-34
UCS	TF	MRPL28	ZNF408	0.8432075	3.87E-34
UCS	TF	MRPL28	AKAP8L	0.843305144	3.74E-34
UCS	TF	MRPL28	CENPB	0.844978057	2.07E-34
UCS	TF	MRPL28	ZNF524	0.846563996	1.17E-34
UCS	TF	MRPL28	DRAP1	0.848056932	6.85E-35
UCS	TF	MRPL28	ZNF668	0.852617775	1.27E-35
UCS	TF	MRPL28	ZNF32	0.859266329	9.78E-37
UCS	TF	MRPL28	REXO4	0.861901533	3.42E-37
UCS	TF	MRPL28	THAP7	0.866335176	5.53E-38
UCS	TF	MRPL28	ZNF688	0.870101352	1.12E-38
UCS	TF	MRPL28	ZNF428	0.898810303	8.39E-45
UCS	TF	MRPL28	THAP3	0.913161824	1.34E-48
UCS	TF	MRPL28	MBD3	0.916682795	1.25E-49
UCS	TF	MRPL28	ZNF787	0.920848051	6.51E-51
UCS	TSG	MRPL28	AIP	0.803854775	7.60E-29
UCS	TSG	MRPL28	PFN1	0.803963227	7.38E-29
UCS	TSG	MRPL28	ZBTB48	0.80845285	2.12E-29
UCS	TSG	MRPL28	GLTSCR2	0.810538411	1.18E-29
UCS	TSG	MRPL28	HTRA2	0.820713117	5.93E-31
UCS	TSG	MRPL28	GNB2L1	0.822255657	3.71E-31
UCS	TSG	MRPL28	PYCARD	0.826550616	9.79E-32
UCS	TSG	MRPL28	STUB1	0.828832055	4.75E-32
UCS	TSG	MRPL28	TUSC2	0.830441273	2.84E-32
UCS	TSG	MRPL28	PHB	0.831522349	2.00E-32
UCS	TSG	MRPL28	ARMC5	0.833314834	1.11E-32
UCS	TSG	MRPL28	MAD1L1	0.834575022	7.36E-33
UCS	TSG	MRPL28	SIRT3	0.843998514	2.93E-34
UCS	TSG	MRPL28	PARK7	0.848603658	5.61E-35
UCS	TSG	MRPL28	ZNF668	0.852617775	1.27E-35
UCS	TSG	MRPL28	NPRL2	0.864343136	1.26E-37
UCS	TSG	MRPL28	GABARAP	0.866968026	4.24E-38
UCS	TSG	MRPL28	BRMS1	0.912073375	2.74E-48
UCS	TSG	MRPL28	GADD45GIP1	0.927365195	4.57E-53
UCS	TSG	MRPL28	SIRT6	0.93091951	2.51E-54
UCS	TSG	MRPL28	TSSC4	0.957935299	6.65E-67
UVM	Cell metabolism gene	MRPL28	TIMM13	0.802557502	3.54E-19
UVM	Cell metabolism gene	MRPL28	GNB2	0.805464416	2.11E-19
UVM	Cell metabolism gene	MRPL28	GEMIN7	0.806220558	1.84E-19
UVM	Cell metabolism gene	MRPL28	PPP2R1A	0.807884332	1.36E-19
UVM	Cell metabolism gene	MRPL28	POLR2E	0.815767003	3.11E-20
UVM	Cell metabolism gene	MRPL28	NME4	0.816689482	2.61E-20
UVM	Cell metabolism gene	MRPL28	SCO2	0.816737141	2.58E-20
UVM	Cell metabolism gene	MRPL28	MED25	0.818081553	1.99E-20
UVM	Cell metabolism gene	MRPL28	DAD1	0.819417606	1.53E-20
UVM	Cell metabolism gene	MRPL28	PSMD8	0.821579716	1.00E-20
UVM	Cell metabolism gene	MRPL28	PLD3	0.823905331	6.30E-21
UVM	Cell metabolism gene	MRPL28	CNOT3	0.826272771	3.90E-21
UVM	Cell metabolism gene	MRPL28	PIGQ	0.828062324	2.70E-21
UVM	Cell metabolism gene	MRPL28	TIMM50	0.829823232	1.87E-21
UVM	Cell metabolism gene	MRPL28	VKORC1	0.832509068	1.06E-21
UVM	Cell metabolism gene	MRPL28	TIMM17B	0.836661952	4.34E-22
UVM	Cell metabolism gene	MRPL28	POLR2I	0.854849322	6.25E-24
UVM	Cell metabolism gene	MRPL28	MTX1	0.856200343	4.46E-24
UVM	Cell metabolism gene	MRPL28	PHKG2	0.857326894	3.35E-24
UVM	Cell metabolism gene	MRPL28	AAAS	0.862368667	9.11E-25
UVM	Cell metabolism gene	MRPL28	TECR	0.865009718	4.51E-25
UVM	Cell metabolism gene	MRPL28	DPM2	0.880089794	5.98E-27
UVM	CGC	MRPL28	PPP2R1A	0.807884332	1.36E-19
UVM	CGC	MRPL28	SH3GL1	0.822721241	7.99E-21
UVM	CGC	MRPL28	TFPT	0.825708219	4.37E-21
UVM	CGC	MRPL28	CNOT3	0.826272771	3.90E-21
UVM	Epifactor	MRPL28	TFPT	0.825708219	4.37E-21
UVM	Epifactor	MRPL28	SUV39H1	0.829957294	1.82E-21
UVM	Epifactor	MRPL28	RNF40	0.830267812	1.71E-21
UVM	Epifactor	MRPL28	PAF1	0.837131788	3.91E-22
UVM	Epifactor	MRPL28	FBRS	0.839148935	2.51E-22
UVM	Epifactor	MRPL28	C17orf49	0.856799228	3.83E-24
UVM	Epifactor	MRPL28	TAF6L	0.869098129	1.47E-25
UVM	Epifactor	MRPL28	BRMS1	0.86922337	1.42E-25
UVM	Epifactor	MRPL28	RUVBL2	0.888157555	4.63E-28
UVM	Epifactor	MRPL28	INO80E	0.889237622	3.24E-28
UVM	IUPHAR	MRPL28	ATP13A1	0.80081074	4.82E-19
UVM	IUPHAR	MRPL28	NUCB1	0.804012548	2.73E-19
UVM	IUPHAR	MRPL28	SLC25A39	0.816832193	2.54E-20
UVM	IUPHAR	MRPL28	SPNS1	0.827708262	2.90E-21
UVM	IUPHAR	MRPL28	ATP6V1F	0.828664519	2.38E-21
UVM	IUPHAR	MRPL28	SUV39H1	0.829957294	1.82E-21
UVM	IUPHAR	MRPL28	VKORC1	0.832509068	1.06E-21
UVM	IUPHAR	MRPL28	PHKG2	0.857326894	3.35E-24
UVM	IUPHAR	MRPL28	ATP6V0C	0.858113057	2.75E-24
UVM	IUPHAR	MRPL28	GSK3A	0.863814989	6.21E-25
UVM	IUPHAR	MRPL28	BCKDK	0.878924808	8.52E-27
UVM	Kinase	MRPL28	PHKG2	0.857326894	3.35E-24
UVM	Kinase	MRPL28	GSK3A	0.863814989	6.21E-25
UVM	Kinase	MRPL28	BCKDK	0.878924808	8.52E-27
UVM	TF	MRPL28	THAP4	0.800654459	4.95E-19
UVM	TF	MRPL28	ZBTB45	0.806604458	1.71E-19
UVM	TF	MRPL28	ZNF444	0.82881807	2.31E-21
UVM	TF	MRPL28	ZNF787	0.834608035	6.78E-22
UVM	TF	MRPL28	ZNF668	0.87793686	1.15E-26
UVM	TSG	MRPL28	CNOT3	0.826272771	3.90E-21
UVM	TSG	MRPL28	PFN1	0.833471456	8.65E-22
UVM	TSG	MRPL28	TSSC4	0.857371394	3.32E-24
UVM	TSG	MRPL28	BRMS1	0.86922337	1.42E-25
UVM	TSG	MRPL28	ZNF668	0.87793686	1.15E-26
UVM	TSG	MRPL28	GADD45GIP1	0.890302575	2.27E-28

Top

Protein structure

Protein 3D structure
Visit iCn3D.

Top

Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
STAD	MRPL28	MRPL15	-2.15546608137429	0.000334546435624361
KIRC	MRPL28	MRPL24	-1.34802117098363	0.000369980864421695
LUSC	MRPL28	MRPL44	-1.0353261138043	0.000533204507372277
LUSC	MRPL28	MRPL39	-3.50411737429004	0.000985010025625636
BLCA	MRPL28	MRPL27	-4.19270554058168	0.00202178955078125
KICH	MRPL28	MRPL24	1.42000841970622	0.00378090143203735
CHOL	MRPL28	MRPL3	-2.68429255990621	0.00390625
BLCA	MRPL28	MRPL39	1.69896851960452	0.00391769409179688
LUAD	MRPL28	MRPL39	-1.1049452981592	0.00471395891927286
ESCA	MRPL28	MRPL3	-4.97897094908275	0.0048828125
COAD	MRPL28	MRPL15	1.17181689924568	0.00513318181037904
PRAD	MRPL28	ICT1	-1.54848444909352	0.00907723161841939
ESCA	MRPL28	MRPL17	-1.18756178214998	0.009765625
KIRP	MRPL28	MRPL38	1.28078686740376	0.0105091729201376
CHOL	MRPL28	MRPL44	-1.84100898736725	0.01171875
LIHC	MRPL28	MRPL17	-1.06225729770915	0.0124123499319886
KIRP	MRPL28	MRPL24	-2.9092481117556	0.0139979305677116
COAD	MRPL28	MRPL39	-1.15285953291756	0.0357243716716767
LUAD	MRPL28	MRPL24	-3.53731160751159	1.10656371043093e-09
BRCA	MRPL28	MRPL27	-1.5584165725499	1.16393956539382e-08
KICH	MRPL28	MRPL15	1.54522142310359	1.19209289550781e-07
STAD	MRPL28	MRPL17	-3.90880705449186	1.49570405483246e-06
LUSC	MRPL28	MRPL15	-4.43702988385305	1.91594862886626e-08
KIRC	MRPL28	MRPL3	1.69955762234244	1.97132191719422e-08
LUAD	MRPL28	MRPL38	-1.82500284003406	2.20741561246108e-05
LIHC	MRPL28	MRPL24	1.01230339617377	2.71217975233539e-06
BRCA	MRPL28	ICT1	-4.17488220449664	2.73719348917167e-14
BRCA	MRPL28	MRPL44	-2.66444869593332	3.06751315169682e-08
LUAD	MRPL28	MRPL27	-1.39404329671842	3.44055922076328e-05
LUSC	MRPL28	MRPL27	-1.81809468729316	3.90393047420304e-06
LUSC	MRPL28	MRPL38	-1.46267889332591	3.90393047420304e-06
LIHC	MRPL28	MRPL39	-1.65461683386216	3.95799979560965e-08
BRCA	MRPL28	MRPL15	-3.82448964360727	5.49451113259074e-14
LUAD	MRPL28	MRPL44	-3.23791370825974	5.91982739853218e-07
LUSC	MRPL28	ICT1	-3.23093376049456	6.60526357089358e-07
LUSC	MRPL28	MRPL17	-6.83409683292749	6.93230040561614e-07
LUSC	MRPL28	MRPL24	-2.80841690659614	7.95689711347621e-09

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPL28

TUBB3, OXA1L, ICT1, CUL3, APP, MRPL32, MRPL41, MRPS7, MRPL9, MRPL23, ILF2, MSLN, NPM1, GRSF1, CDR2, TEF, TRAF4, TRAF3IP2, IKZF3, BANP, HMBOX1, FAM9B, RPL13, MRPL45, MRPL46, MRPL40, MRPL3, MRPL1, MRPL39, MRPL22, MRPL37, MRPL24, MRPL49, MRPL44, MRPL50, MRPL38, RPS8, MRPL27, MRPL55, MRPL47, MRPL16, MRPL19, HNRNPA1, MRPL15, MRPL2, MRPL13, MRPL17, MRPL4, GADD45GIP1, MRPL30, MRPS30, MRPL20, MRPL14, MRPS18A, RNMTL1, MALSU1, MRPL57, MRPL34, HSPB1, NTRK1, APMAP, AURKA, Cep72, ZNF131, MRPL10, MRPL42, MRPL35, ZNF331, MRPL12, RPL18, EFTUD2, LRRK2, RECQL4, SERBP1, HIST1H3A, RPS6, MRM1, PDK1, TRMT61B, AURKAIP1, LTN1, ALYREF, SNRNP70, UPP2, USP2, LENG1, PPL, TSHZ3, ENKD1, USP20, ABI2, LARP1B, TSSK3, SCNM1, CDCA7L, NFKBID, ZNF655, PRKCI, HTRA2, nsp6, HSCB, ZC3HAV1, CIT, ARHGAP36, ACAD9, AUH, C12orf65, C17orf80, C1QBP, C21orf33, C6orf203, C8orf82, CHCHD1, CS, DDX28, DHX30, FASTKD2, FASTKD3, FASTKD5, GFM1, GFM2, HINT2, LRPPRC, MCU, CCDC109B, MDH2, METTL15, METTL17, MRPL11, MRPS12, MRPS26, MRRF, MTERF3, MTFMT, MTG1, MTG2, MTIF2, MTIF3, MTRF1, MTRF1L, NGRN, PMPCA, PMPCB, RPUSD4, SLIRP, SSBP1, TACO1, TBRG4, TFAM, TMEM70, TRUB2, TSFM, TUFM, VWA8, EXD2, NR3C1, DNAJC15, SMYD3, MRPL18, SRSF10, TUBGCP4, C14orf169, MRPL21, PRR3, ZNF346, RPL23A, HIST1H2AM, ABT1, RPL19, SRSF6, SRSF4, RPL27A, YBX2, SRSF5, RPL26, RPL37, H1FNT, THAP3, GNL3, RBMS2, HNRNPU, FAM120A, YBX1, LIN28A, H2AFB3, UTP23, RPL3, SRSF3, NEIL1, MRPL51, RPS3A, ZNF467, LIN28B, RPL17, MRPL53, RPL35, MRPS17, MRPL52, RPL13A, APOBEC3D, RPL10, ZNF574, SRSF7, MRPL33, MRPL43, FAHD1, RBMS3, MRPL48, RPL36AL, MRPS25, NDUFAB1, ZFYVE1, Nudt21, KLF15, BRD4,

Top

Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
MRPL28	chr16	418381	C	T	single_nucleotide_variant	Likely_benign	Oromandibular-limb_hypogenesis_spectrum	SO:0001583\|missense_variant	SO:0001583\|missense_variant
MRPL28	chr16	419086	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
MRPL28	chr16	420043	C	G	single_nucleotide_variant	Likely_benign	Oromandibular-limb_hypogenesis_spectrum	SO:0001583\|missense_variant	SO:0001583\|missense_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPL28	STAD	chr16	418359	418359	G	A	Missense_Mutation	p.A211V	4
MRPL28	ESCA	chr16	418610	418610	T	G	Missense_Mutation	p.K156T	3
MRPL28	PAAD	chr16	419132	419132	G	A	Missense_Mutation	p.T126I	3
MRPL28	SKCM	chr16	418546	418546	G	A	Silent	p.H177H	2
MRPL28	SKCM	chr16	418402	418402	G	C	Missense_Mutation	p.P197A	2
MRPL28	SKCM	chr16	419071	419071	G	C	Silent	p.L146L	2
MRPL28	CESC	chr16	419154	419154	G	A	Silent		2
MRPL28	STAD	chr16	419990	419990	G	A	Missense_Mutation		2
MRPL28	THYM	chr16	417729	417729	C	T	Silent		2
MRPL28	STAD	chr16	419105	419105	A	T	Missense_Mutation		2
MRPL28	THYM	chr16	418359	418359	G	A	Missense_Mutation		2
MRPL28	STAD	chr16	419105	419105	A	T	Missense_Mutation	p.I135N	2
MRPL28	ESCA	chr16	418610	418610	T	G	Missense_Mutation		2
MRPL28	UCEC	chr16	418578	418578	G	A	Silent	p.L167	2
MRPL28	PAAD	chr16	419132	419132	G	A	Missense_Mutation		2
MRPL28	STAD	chr16	419103	419103	C	T	Missense_Mutation	p.D136N	2
MRPL28	UCEC	chr16	419091	419091	C	T	Missense_Mutation	p.G140R	2
MRPL28	STAD	chr16	418565	418565	C	T	Missense_Mutation	p.R171Q	2
MRPL28	PRAD	chr16	418564	418564	C	T	Silent	p.R171R	2
MRPL28	LIHC	chr16	419990	419990	G	A	Missense_Mutation	p.R77W	2
MRPL28	CHOL	chr16	419636	419636	T	C	Missense_Mutation		1
MRPL28	LIHC	chr16	419613	419613	C	-	Frame_Shift_Del	p.G14fs	1
MRPL28	CHOL	chr16	419639	419639	C	G	Missense_Mutation		1
MRPL28	STAD	chr16	419175	419175	G	A	Nonsense_Mutation		1
MRPL28	LIHC	chr16	420000	420000	G	-	Frame_Shift_Del	p.P73fs	1
MRPL28	COAD	chr16	419104	419104	G	T	Silent	p.I135I	1
MRPL28	TGCT	chr16	418597	418597	G	C	Missense_Mutation		1
MRPL28	LUAD	chr16	418328	418328	C	G	Splice_Site	p.K221_splice	1
MRPL28	BLCA	chr16	417715	417715	G	C	Nonsense_Mutation	p.S244*	1
MRPL28	COAD	chr16	420023	420023	G	A	Missense_Mutation	p.P66S	1
MRPL28	THCA	chr16	417713	417713	C	A	Nonsense_Mutation	p.E245*	1
MRPL28	LUAD	chr16	419158	419158	C	T	Silent	p.E117E	1
MRPL28	DLBC	chr16	417691	417691	C	G	Missense_Mutation	p.R252T	1
MRPL28	LUAD	chr16	418630	418630	C	-	Frame_Shift_Del	p.P149fs	1
MRPL28	CESC	chr16	420123	420123	C	T	Silent		1
MRPL28	LUSC	chr16	419061	419061	C	T	Missense_Mutation		1
MRPL28	CESC	chr16	420171	420171	C	T	Silent		1
MRPL28	THYM	chr16	417729	417729	C	T	Silent	p.Q239Q	1
MRPL28	OV	chr16	358371	358371	C	T	Silent	p.T207	1
MRPL28	CESC	chr16	419128	419128	C	A	Silent		1
MRPL28	STAD	chr16	419175	419175	G	A	Nonsense_Mutation	p.R112X	1
MRPL28	GBM	chr16	418589	418589	C	T	Missense_Mutation		1
MRPL28	CESC	chr16	419128	419128	C	A	Silent	p.V127	1
MRPL28	LIHC	chr16	420008	420008	A	G	Missense_Mutation		1
MRPL28	CESC	chr16	420123	420123	C	T	Silent	p.L32	1
MRPL28	LIHC	chr16	419092	419092	A	G	Silent		1
MRPL28	CESC	chr16	420171	420171	C	T	Silent	p.L16	1
MRPL28	STAD	chr16	419175	419175	G	A	Nonsense_Mutation	p.R112*	1
MRPL28	SARC	chr16	419689	419689	G	A	Missense_Mutation		1

Copy number variation (CNV) of MRPL28
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPL28
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
103323	N/A	AI871355	ACER2	chr9	19448319	+	MRPL28	chr16	417396	+
103323	STAD	TCGA-VQ-A8PJ-01A	AXIN1	chr16	402369	-	MRPL28	chr16	418635	-
103323	N/A	AC005202	AXIN1	chr16	401054	+	MRPL28	chr16	407691	+
103323	N/A	AA612851	CHFR	chr12	133470821	+	MRPL28	chr16	417396	+
103323	N/A	AA528112	KIF21A	chr12	39714447	-	MRPL28	chr16	417396	+
90754	N/A	BG032594	MRPL28	chr16	417397	-	LARS	chr5	145560896	+
103323	N/A	AA328884	MRPL28	chr16	417718	-	MRPL28	chr16	420096	-
102397	N/A	BG576445	MRPL28	chr16	417396	-	NFIA	chr1	61442740	+
66441	N/A	BF360513	MRPL28	chr16	418637	+	RARRES3	chr11	63312122	+
103323	N/A	AW005815	PRR11	chr17	57282427	-	MRPL28	chr16	417396	+
103323	N/A	AI676243	RP11-679C8.2	chr4	120999726	-	MRPL28	chr16	417396	+
103323	N/A	AI676252	SENP2	chr3	185342374	-	MRPL28	chr16	417396	+
103330	N/A	BM504087	ZZEF1	chr17	4001100	-	MRPL28	chr16	417396	+

Top

Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

Top

Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	MRPL28	0.0120435868944405	0.33
TGCT	MRPL28	0.0142364166232602	0.37
ACC	MRPL28	0.0223382472294785	0.56
THYM	MRPL28	0.0379959634772929	0.91
KIRP	MRPL28	1.08954463188247e-05	0.00031

Top

Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	MRPL28	0.00934773246439731	0.3
THCA	MRPL28	0.0406074393203516	1
KIRP	MRPL28	0.037609258951504	1
BRCA	MRPL28	0.0091552625160572	0.3
OV	MRPL28	0.0134255343300404	0.42

Top

Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source