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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: EXOSC7 (NCBI Gene ID:23016)

Gene Summary

Gene Summary

Gene Information	Gene Name: EXOSC7
	Gene ID: 23016
	Gene Symbol	EXOSC7
	Gene ID	23016
	Gene Name	exosome component 7
	Synonyms	EAP1\|RRP42\|Rrp42p\|hRrp42p\|p8
	Cytomap	3p21.31
	Type of Gene	protein-coding
	Description	exosome complex component RRP42exosome complex exonuclease RRP42ribosomal RNA-processing protein 42
	Modification date	20200313
	UniProtAcc	Q15024

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0017148	Negative regulation of translation
GO:0006417	Regulation of translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
EXOSC7	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'EXOSC7[title] AND translation [title] AND human.'

Gene	Title	PMID
EXOSC7	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000265564	45030631	45030733	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000265564	45030631	45030733	1072	106	207	291	19	53

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q15024	19	53	2	291	Chain	ID=PRO_0000139963;Note=Exosome complex component RRP42
Q15024	19	53	8	19	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:2NN6
Q15024	19	53	24	26	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:2NN6
Q15024	19	53	36	39	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:2NN6
Q15024	19	53	45	53	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:2NN6

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KICH	EXOSC7	1.11626022550606	0.00963503122329712
UCEC	EXOSC7	1.37141709218626	0.015625

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type	Gene	miRNA	TargetScan binding score (Context++ score percentile)	Coefficient	Pvalue
ACC	EXOSC7	hsa-miR-155-5p	91	0.306085686465433	0.00626921067188704

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
THYM	EXOSC7	2	1	0.0477973106813848	0.287415507246377	0.166951515151515	-0.378287831855174	-0.795191072962618

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
LUSC	EXOSC7	-0.100070157	0.024434425

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with EXOSC7 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	EXOSC7	POLR2F	0.802771903	6.76E-12
DLBC	Cell metabolism gene	EXOSC7	LSM3	0.803882306	6.01E-12
DLBC	Cell metabolism gene	EXOSC7	POLR2L	0.806774175	4.42E-12
DLBC	Cell metabolism gene	EXOSC7	PSMB3	0.810148917	3.06E-12
DLBC	Cell metabolism gene	EXOSC7	POLR2I	0.813697245	2.07E-12
DLBC	Cell metabolism gene	EXOSC7	PPCDC	0.815492258	1.69E-12
DLBC	Cell metabolism gene	EXOSC7	PMPCA	0.823225163	6.89E-13
DLBC	Cell metabolism gene	EXOSC7	TIMM13	0.830358321	2.90E-13
DLBC	Epifactor	EXOSC7	SS18L2	0.885169142	6.81E-17
DLBC	IUPHAR	EXOSC7	SLC25A26	0.808469947	3.68E-12
DLBC	TF	EXOSC7	THAP3	0.800397764	8.65E-12
DLBC	TSG	EXOSC7	TSSC4	0.811736152	2.57E-12
DLBC	TSG	EXOSC7	GADD45GIP1	0.812515359	2.36E-12
PCPG	IUPHAR	EXOSC7	CAMK1	0.830704535	6.15E-49
PCPG	Kinase	EXOSC7	CAMK1	0.830704535	6.15E-49
THYM	Cell metabolism gene	EXOSC7	ACOT8	0.800105876	2.10E-28
THYM	Cell metabolism gene	EXOSC7	DPM2	0.800504311	1.89E-28
THYM	Cell metabolism gene	EXOSC7	SEC13	0.801464285	1.46E-28
THYM	Cell metabolism gene	EXOSC7	POLR2I	0.801707232	1.36E-28
THYM	Cell metabolism gene	EXOSC7	PSMD9	0.80273879	1.03E-28
THYM	Cell metabolism gene	EXOSC7	SNRPD2	0.803944534	7.42E-29
THYM	Cell metabolism gene	EXOSC7	TIMM8B	0.805605872	4.70E-29
THYM	Cell metabolism gene	EXOSC7	PGLS	0.807024433	3.17E-29
THYM	Cell metabolism gene	EXOSC7	PSMB1	0.816608256	2.02E-30
THYM	Cell metabolism gene	EXOSC7	POLR2F	0.821917389	4.11E-31
THYM	Cell metabolism gene	EXOSC7	PSMC3	0.842453897	5.04E-34
THYM	Epifactor	EXOSC7	PRPF31	0.822829231	3.11E-31
THYM	IUPHAR	EXOSC7	PSMB1	0.816608256	2.02E-30
THYM	TF	EXOSC7	ZNF428	0.822214631	3.75E-31
THYM	TSG	EXOSC7	TSSC4	0.8119994	7.75E-30
UCS	Cell metabolism gene	EXOSC7	ACOT8	0.800105876	2.10E-28
UCS	Cell metabolism gene	EXOSC7	DPM2	0.800504311	1.89E-28
UCS	Cell metabolism gene	EXOSC7	SEC13	0.801464285	1.46E-28
UCS	Cell metabolism gene	EXOSC7	POLR2I	0.801707232	1.36E-28
UCS	Cell metabolism gene	EXOSC7	PSMD9	0.80273879	1.03E-28
UCS	Cell metabolism gene	EXOSC7	SNRPD2	0.803944534	7.42E-29
UCS	Cell metabolism gene	EXOSC7	TIMM8B	0.805605872	4.70E-29
UCS	Cell metabolism gene	EXOSC7	PGLS	0.807024433	3.17E-29
UCS	Cell metabolism gene	EXOSC7	PSMB1	0.816608256	2.02E-30
UCS	Cell metabolism gene	EXOSC7	POLR2F	0.821917389	4.11E-31
UCS	Cell metabolism gene	EXOSC7	PSMC3	0.842453897	5.04E-34
UCS	Epifactor	EXOSC7	PRPF31	0.822829231	3.11E-31
UCS	IUPHAR	EXOSC7	PSMB1	0.816608256	2.02E-30
UCS	TF	EXOSC7	ZNF428	0.822214631	3.75E-31
UCS	TSG	EXOSC7	TSSC4	0.8119994	7.75E-30
UVM	Cell metabolism gene	EXOSC7	SEC13	0.800429846	5.15E-19
UVM	Cell metabolism gene	EXOSC7	POLR2H	0.834486705	6.95E-22
UVM	TSG	EXOSC7	NPRL2	0.818645407	1.78E-20

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	EXOSC7	EXOSC1	-1.33151185162103	0.000133869703859091
KICH	EXOSC7	EXOSC10	1.24998522750894	0.000139892101287842
THCA	EXOSC7	EXOSC4	-1.11463631149166	0.000207398306454043
STAD	EXOSC7	EXOSC2	-2.44541936914958	0.000280400272458792
KICH	EXOSC7	EXOSC1	1.88198428035622	0.000556409358978271
PRAD	EXOSC7	SKIV2L2	-1.27775550240692	0.000627023923094011
PRAD	EXOSC7	EXOSC4	-4.70182019022102	0.000648342999076925
ESCA	EXOSC7	EXOSC5	-3.73448090208876	0.0009765625
LIHC	EXOSC7	EXOSC4	2.269913876739	0.00228509329229136
ESCA	EXOSC7	DIS3	1.13528932331943	0.0029296875
BLCA	EXOSC7	MPHOSPH6	1.68807157110571	0.00457763671875
STAD	EXOSC7	EXOSC3	-1.95167394249126	0.00733334058895707
LIHC	EXOSC7	DIS3	1.39544325555059	0.00915034805063108
LIHC	EXOSC7	SKIV2L2	-1.18110700879315	0.0175629065961987
KICH	EXOSC7	MPHOSPH6	-1.16662499083698	0.0341737866401672
BRCA	EXOSC7	EXOSC1	-3.22250485955442	1.01918341406027e-11
KIRC	EXOSC7	EXOSC5	-2.76908351745065	1.09859684701495e-11
PRAD	EXOSC7	EXOSC5	-2.70222350851716	1.26099370313262e-05
BRCA	EXOSC7	EXOSC4	-1.39844269640225	1.3684078260725e-15
THCA	EXOSC7	EXOSC5	-1.76982463038815	1.55304155962675e-06
LUAD	EXOSC7	EXOSC5	-2.21263383713822	1.8775400044567e-09
KIRC	EXOSC7	EXOSC2	-1.19651027966078	1.90834783211408e-08
THCA	EXOSC7	SKIV2L2	-3.0696404754071	4.37037666427901e-06
LUAD	EXOSC7	EXOSC4	-2.39057665546458	5.24732369463512e-07
LUAD	EXOSC7	EXOSC3	-2.13410426948851	5.48906105617824e-05
LUAD	EXOSC7	EXOSC10	-5.48154088649683	6.13939009668372e-06
KIRP	EXOSC7	EXOSC5	-1.57899571115575	6.79492950439454e-06
THCA	EXOSC7	EXOSC3	1.35051614908302	7.77019962091197e-05
LUAD	EXOSC7	EXOSC2	-1.64534827889499	8.78996847588964e-09
BRCA	EXOSC7	EXOSC5	-1.24930553971161	9.66917351405126e-09

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with EXOSC7

EXOSC6, IP6K1, EXOSC1, EXOSC2, EXOSC4, DIS3, DIS3L, EXOSC3, APP, AICDA, EXOSC10, DXO, HECW2, rev, RPA3, RPA2, RPA1, TP53, RBM7, MPHOSPH6, EXOSC8, SKIV2L2, HBS1L, EXOSC9, EXOSC5, ZCCHC8, ZFC3H1, C1D, USP30, GIGYF2, IFI16, GDI1, HDAC1, TSNAX, MRPL50, MZT1, Exosc1, Rrbp1, LUM, RSRC1, SLIT2, LRRC47, DHPS, EFTUD2, ESR2, RECQL4, ATG16L1, BICD2, SNRNP70, CYLD, NFX1, BRD7, UBE2K, ESRRG, ARIH2, OBSL1, PLEKHA4, ENG, PTEN, ZC3H18, ESR1, MNDA, MKI67, NMRAL1, THOP1, EIF4E2, PARP8, nsp2, DDRGK1, FZR1, PRPF6, EIF4ENIF1, VIM, KIF24, TFIP11, C1orf35, KRT31, SNRNP48, EHMT2, UNKL, RBM22, RALYL, HOOK1, CCDC59, RBPMS, DGCR14, PRC1, PRRC2B, MIF, SNW1, ALG13, SUPT5H, DMRTB1, THOC1, LARP4, RPL21, DPYSL2, Sf3b2, Ssbp1, Fez2, Zcchc17, Bbs5, Ube2i, Nudt21, Cnn3, Mapre3, Mrps31, Dynlt1b, Tsnax, Htatsf1, Rbm14, Pspc1, Eif3g, Sf3a3, Nufip2, Grb2, Zc3h11a, Nhp2l1, SIRT6,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
EXOSC7	KIRP	chr3	45048921	45048921	C	T	Missense_Mutation	p.R209W	4
EXOSC7	KIRP	chr3	45038724	45038724	G	C	Missense_Mutation	p.V134L	4
EXOSC7	LUAD	chr3	45038682	45038682	G	T	Missense_Mutation	p.D120Y	4
EXOSC7	LUAD	chr3	45052814	45052814	G	T	Missense_Mutation	p.V287F	3
EXOSC7	LUAD	chr3	45052818	45052818	G	T	Missense_Mutation	p.G288V	3
EXOSC7	SKCM	chr3	45030635	45030635	G	A	Missense_Mutation	p.D21N	3
EXOSC7	UCEC	chr3	45046872	45046872	T	C	Missense_Mutation	p.V194A	3
EXOSC7	UCEC	chr3	45048983	45048983	G	A	Silent	p.S229	2
EXOSC7	SKCM	chr3	45046817	45046817	G	A	Missense_Mutation	p.G176R	2
EXOSC7	STAD	chr3	45038655	45038655	C	T	Missense_Mutation	p.R111W	2
EXOSC7	ESCA	chr3	45046822	45046822	G	A	Silent		2
EXOSC7	SKCM	chr3	45048959	45048959	C	-	Frame_Shift_Del	p.C221fs	2
EXOSC7	STAD	chr3	45038709	45038709	C	T	Missense_Mutation	p.R129W	2
EXOSC7	ESCA	chr3	45046822	45046822	G	A	Silent	p.S177S	2
EXOSC7	SKCM	chr3	45052801	45052801	C	A	Silent	p.P282P	2
EXOSC7	SKCM	chr3	45030653	45030653	C	T	Missense_Mutation	p.R27C	2
EXOSC7	SKCM	chr3	45048923	45048923	G	A	Silent	p.R209R	2
EXOSC7	LIHC	chr3	45046818	45046818	G	C	Missense_Mutation		2
EXOSC7	BRCA	chr3	45030632	45030632	G	A	Missense_Mutation	p.E20K	2
EXOSC7	LIHC	chr3	45046818	45046818	G	C	Missense_Mutation	p.G176A	2
EXOSC7	HNSC	chr3	45052755	45052755	A	T	Missense_Mutation	p.H267L	2
EXOSC7	LIHC	chr3	45048999	45048999	G	T	Missense_Mutation	p.V235F	2
EXOSC7	UCEC	chr3	45031125	45031125	C	A	Missense_Mutation	p.F81L	2
EXOSC7	SARC	chr3	45048925	45048925	A	T	Missense_Mutation	p.H210L	2
EXOSC7	LIHC	chr3	45046800	45046800	T	-	Frame_Shift_Del	p.V170fs	2
EXOSC7	UCEC	chr3	45038599	45038599	A	C	Missense_Mutation	p.E92A	2
EXOSC7	SKCM	chr3	45030640	45030640	C	T	Silent	p.L22L	1
EXOSC7	LUAD	chr3	45038690	45038690	G	C	Missense_Mutation	p.K122N	1
EXOSC7	COAD	chr3	45052750	45052750	A	G	Silent	p.V265V	1
EXOSC7	SKCM	chr3	45031102	45031102	C	T	Missense_Mutation	p.P74S	1
EXOSC7	ESCA	chr3	45046822	45046822	G	A	Silent	p.S177	1
EXOSC7	SKCM	chr3	45048961	45048961	C	T	Missense_Mutation	p.S222L	1
EXOSC7	KIRP	chr3	45049021	45049021	T	G	Missense_Mutation		1
EXOSC7	KIRP	chr3	45038724	45038724	G	C	Missense_Mutation		1
EXOSC7	BLCA	chr3	45038611	45038611	G	C	Missense_Mutation		1
EXOSC7	KIRP	chr3	45048921	45048921	C	T	Missense_Mutation		1
EXOSC7	STAD	chr3	45030680	45030680	G	A	Missense_Mutation	p.E36K	1
EXOSC7	BLCA	chr3	45038647	45038647	C	T	Missense_Mutation		1
EXOSC7	LUAD	chr3	45030648	45030648	A	G	Missense_Mutation	p.D25G	1
EXOSC7	HNSC	chr3	45052755	45052755	A	T	Missense_Mutation		1
EXOSC7	LIHC	chr3	45052761	45052761	C	T	Missense_Mutation		1
EXOSC7	STAD	chr3	45038710	45038710	G	A	Missense_Mutation	p.R129Q	1
EXOSC7	BLCA	chr3	45038611	45038611	G	C	Missense_Mutation	p.R96T	1
EXOSC7	READ	chr3	45038681	45038681	C	T	Silent	p.V119V	1
EXOSC7	HNSC	chr3	45049058	45049058	G	A	Silent		1
EXOSC7	LIHC	chr3	45048999	45048999	G	T	Missense_Mutation		1
EXOSC7	BLCA	chr3	45052768	45052768	G	C	Missense_Mutation	p.Q271H	1
EXOSC7	READ	chr3	45030718	45030718	C	A	Silent	p.S48S	1
EXOSC7	HNSC	chr3	45052822	45052822	C	T	Silent		1
EXOSC7	UCEC	chr3	45048983	45048983	G	A	Silent	p.S229S	1
EXOSC7	SARC	chr3	45048925	45048925	A	T	Missense_Mutation		1
EXOSC7	HNSC	chr3	45049058	45049058	G	A	Silent	p.E254E	1
EXOSC7	SKCM	chr3	45038639	45038639	C	T	Silent	p.I105I	1
EXOSC7	UCEC	chr3	45030719	45030719	G	A	Missense_Mutation	p.A49T	1
EXOSC7	CESC	chr3	45052775	45052775	G	C	Missense_Mutation		1
EXOSC7	SARC	chr3	45043081	45043081	G	T	Missense_Mutation		1
EXOSC7	SKCM	chr3	45046796	45046796	C	T	Nonsense_Mutation	p.R169*	1
EXOSC7	COAD	chr3	45038695	45038695	T	G	Missense_Mutation	p.L124R	1
EXOSC7	HNSC	chr3	45052822	45052822	C	T	Silent	p.F289F	1
EXOSC7	SKCM	chr3	45038727	45038727	C	T	Missense_Mutation	p.L135F	1
EXOSC7	COAD	chr3	45048962	45048962	G	A	Silent	p.S222S	1
EXOSC7	SKCM	chr3	45046796	45046796	C	T	Nonsense_Mutation	p.R169X	1

Copy number variation (CNV) of EXOSC7
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across EXOSC7
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
73495	N/A	AI791311	AKAP13	chr15	86109896	+	EXOSC7	chr3	45019582	-
73495	STAD	TCGA-BR-8081	ANKRD28	chr3	15836729	-	EXOSC7	chr3	45030631	+
73495	N/A	EC584247	CDCP1	chr3	45158508	-	EXOSC7	chr3	45052222	-
73495	N/A	CF138765	COX7A2L	chr2	42596367	-	EXOSC7	chr3	45053662	+
73495	N/A	CD653303	EVL	chr14	100479768	+	EXOSC7	chr3	45022937	+
85629	N/A	BI491255	EXOSC7	chr3	45052725	-	CDC42BPA	chr1	227469242	+
73495	N/A	CB241820	EXOSC7	chr3	45053938	-	EXOSC7	chr3	45052836	+
102773	N/A	AW020214	EXOSC7	chr3	45052968	+	MELK	chr9	36616838	-
99892	N/A	AA526248	EXOSC7	chr3	45019582	+	SS18	chr18	23649469	+
84621	LUSC	TCGA-66-2763-01A	EXOSC7	chr3	45017826	+	ZDHHC3	chr3	44975476	-
84621	LUSC	TCGA-O2-A5IB-01A	EXOSC7	chr3	45017826	+	ZDHHC3	chr3	45000952	-
73542	PRAD	TCGA-KK-A6E3-01A	RERE	chr1	8716032	-	EXOSC7	chr3	45030632	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	EXOSC7	0.00534880663033548	0.15
THYM	EXOSC7	0.0112130966213523	0.3
LIHC	EXOSC7	0.0144231680624152	0.38
KIRC	EXOSC7	0.0223810236561566	0.56

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	EXOSC7	0.00369583400205194	0.12
THCA	EXOSC7	0.0350079991328707	1
KIRP	EXOSC7	0.00834007826056671	0.27
BRCA	EXOSC7	0.0371783692916391	1
COAD	EXOSC7	0.0464439978073178	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source