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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: PLXNB2 (NCBI Gene ID:23654)

Gene Summary

Gene Summary

Gene Information	Gene Name: PLXNB2
	Gene ID: 23654
	Gene Symbol	PLXNB2
	Gene ID	23654
	Gene Name	plexin B2
	Synonyms	MM1\|Nbla00445\|PLEXB2\|dJ402G11.3
	Cytomap	22q13.33
	Type of Gene	protein-coding
	Description	plexin-B2
	Modification date	20200313
	UniProtAcc	O15031

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0045727	Positive regulation of translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	PLXNB2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	16122393
Hgene	PLXNB2	GO:0010976	positive regulation of neuron projection development	16122393

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

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Translation Studies in PubMed

We searched PubMed using 'PLXNB2[title] AND translation [title] AND human.'

Gene	Title	PMID
PLXNB2	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000359337	50715270	50715335	Frame-shift
ENST00000449103	50715270	50715335	Frame-shift
ENST00000359337	50718058	50718205	In-frame
ENST00000449103	50718058	50718205	In-frame
ENST00000359337	50718433	50718500	Frame-shift
ENST00000449103	50718433	50718500	Frame-shift
ENST00000359337	50720612	50720742	Frame-shift
ENST00000449103	50720612	50720742	Frame-shift
ENST00000359337	50721478	50721615	Frame-shift
ENST00000449103	50721478	50721615	Frame-shift
ENST00000359337	50722560	50722642	Frame-shift
ENST00000449103	50722560	50722642	Frame-shift
ENST00000359337	50723001	50723094	In-frame
ENST00000449103	50723001	50723094	In-frame
ENST00000359337	50724228	50724330	In-frame
ENST00000449103	50724228	50724330	In-frame
ENST00000359337	50725539	50725693	Frame-shift
ENST00000449103	50725539	50725693	Frame-shift
ENST00000359337	50726095	50726222	Frame-shift
ENST00000449103	50726095	50726222	Frame-shift
ENST00000359337	50727945	50729026	3UTR-3CDS
ENST00000449103	50727945	50729026	3UTR-3CDS
ENST00000359337	50733147	50733207	3UTR-3UTR
ENST00000449103	50733154	50733207	3UTR-3UTR

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000359337	50718058	50718205	6368	4352	4498	1838	1414	1463
ENST00000449103	50718058	50718205	6400	4384	4530	1838	1414	1463
ENST00000359337	50723001	50723094	6368	2198	2290	1838	696	727
ENST00000449103	50723001	50723094	6400	2230	2322	1838	696	727
ENST00000359337	50724228	50724330	6368	2096	2197	1838	662	696
ENST00000449103	50724228	50724330	6400	2128	2229	1838	662	696

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
O15031	696	727	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	1414	1463	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	662	696	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	696	727	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	1414	1463	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	662	696	20	1838	Chain	ID=PRO_0000024673;Note=Plexin-B2
O15031	696	727	20	1197	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	662	696	20	1197	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	696	727	20	1197	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	662	696	20	1197	Topological domain	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	1414	1463	1219	1838	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	1414	1463	1219	1838	Topological domain	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
O15031	1414	1463	1462	1469	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:4E71
O15031	1414	1463	1462	1469	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:4E71

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
STAD	PLXNB2	1.0704219528128	0.0093395933508873
THCA	PLXNB2	2.68605428505058	7.49003326178242e-10

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
KIRC	PLXNB2	3	2	0.0134505554092175	0.649385731918239	0.572006688596491	-0.51675882088348	-0.643346824855674
LUAD	PLXNB2	3	2	0.0269100418647071	0.667451883425245	0.568503515625001	0.073177710748138	0.244407122512773

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
UCEC	PLXNB2	3	2	0.04505079509938	0.687464407612032	0.550965057471265	-0.560184839674956	-0.958049871109493

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
PCPG	PLXNB2	-0.088996448	0.027117153

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with PLXNB2 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
THYM	Cell metabolism gene	PLXNB2	FKBP9	0.812592861	6.53E-30
THYM	Cell metabolism gene	PLXNB2	UGGT2	0.824504098	1.85E-31
THYM	Cell metabolism gene	PLXNB2	PISD	0.82810868	5.99E-32
THYM	Cell metabolism gene	PLXNB2	SDC4	0.830988308	2.38E-32
THYM	Cell metabolism gene	PLXNB2	AGRN	0.842137408	5.63E-34
THYM	CGC	PLXNB2	FKBP9	0.812592861	6.53E-30
THYM	CGC	PLXNB2	ZNRF3	0.827264967	7.82E-32
THYM	CGC	PLXNB2	SDC4	0.830988308	2.38E-32
THYM	IUPHAR	PLXNB2	CAPN2	0.805938339	4.28E-29
THYM	IUPHAR	PLXNB2	MMP14	0.810347829	1.24E-29
THYM	IUPHAR	PLXNB2	LTBR	0.817966916	1.35E-30
THYM	IUPHAR	PLXNB2	PISD	0.82810868	5.99E-32
THYM	IUPHAR	PLXNB2	ITGA3	0.841919066	6.08E-34
THYM	TF	PLXNB2	KLF11	0.823573975	2.47E-31
UCS	Cell metabolism gene	PLXNB2	FKBP9	0.812592861	6.53E-30
UCS	Cell metabolism gene	PLXNB2	UGGT2	0.824504098	1.85E-31
UCS	Cell metabolism gene	PLXNB2	PISD	0.82810868	5.99E-32
UCS	Cell metabolism gene	PLXNB2	SDC4	0.830988308	2.38E-32
UCS	Cell metabolism gene	PLXNB2	AGRN	0.842137408	5.63E-34
UCS	CGC	PLXNB2	FKBP9	0.812592861	6.53E-30
UCS	CGC	PLXNB2	ZNRF3	0.827264967	7.82E-32
UCS	CGC	PLXNB2	SDC4	0.830988308	2.38E-32
UCS	IUPHAR	PLXNB2	CAPN2	0.805938339	4.28E-29
UCS	IUPHAR	PLXNB2	MMP14	0.810347829	1.24E-29
UCS	IUPHAR	PLXNB2	LTBR	0.817966916	1.35E-30
UCS	IUPHAR	PLXNB2	PISD	0.82810868	5.99E-32
UCS	IUPHAR	PLXNB2	ITGA3	0.841919066	6.08E-34
UCS	TF	PLXNB2	KLF11	0.823573975	2.47E-31

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LUSC	PLXNB2	RND3	1.04818253915572	0.000102202753672845
BLCA	PLXNB2	RND3	-1.46994698351353	0.000335693359375
KICH	PLXNB2	SEMA3E	1.26583935097358	0.00115483999252319
LUAD	PLXNB2	ARHGEF12	-1.29693734156383	0.00121089428940613
THCA	PLXNB2	SEMA3E	1.72226565186768	0.00146528750243568
COAD	PLXNB2	RRAS	-1.30958080984356	0.00160405039787293
STAD	PLXNB2	SEMA3E	-1.55829472292672	0.00275033386424184
COAD	PLXNB2	SEMA4F	-1.00124180744174	0.00322914123535157
KICH	PLXNB2	RND3	2.60438944099854	0.00378090143203735
COAD	PLXNB2	SEMA3F	-2.44917846077769	0.00390031933784485
CHOL	PLXNB2	RND3	-3.50360238513578	0.00390625
CHOL	PLXNB2	SEMA4F	-4.45345226581299	0.00390625
CHOL	PLXNB2	ARHGEF12	-3.54986118090384	0.0078125
CHOL	PLXNB2	SEMA4D	-1.65355850561595	0.0078125
BRCA	PLXNB2	SEMA4F	-1.2313924469295	0.00820001368943606
ESCA	PLXNB2	SEMA4F	-4.4630640107767	0.013671875
ESCA	PLXNB2	MET	1.7974042761042	0.0185546875
KIRP	PLXNB2	ARHGEF11	-2.93532839044973	0.0194480954669416
CHOL	PLXNB2	RND1	-1.12834179347783	0.01953125
COAD	PLXNB2	RND3	-1.03108570831106	0.0381683111190796
CHOL	PLXNB2	SEMA3F	-1.27913303181879	0.0390625
LIHC	PLXNB2	SEMA4F	-1.46434046993899	1.09871251804152e-08
KIRC	PLXNB2	SEMA4D	-1.33732417750527	1.29783194913552e-06
THCA	PLXNB2	RRAS	2.55390821223837	1.34811402718136e-08
KIRC	PLXNB2	SEMA3F	2.05843236258847	1.44148329893084e-11
THCA	PLXNB2	MET	2.09020268709397	1.50904867455457e-10
KIRC	PLXNB2	SEMA3E	2.08793305515575	1.55238188425888e-10
HNSC	PLXNB2	SEMA3E	4.22690714032052	1.99774895008887e-05
KICH	PLXNB2	SEMA3F	1.63660477609347	2.5629997253418e-06
LUSC	PLXNB2	SEMA3F	2.63153116267794	3.32807340670689e-07
LIHC	PLXNB2	SEMA3E	3.8823538866985	3.59406613648813e-06
LUAD	PLXNB2	RRAS	-4.22934415046406	3.59910232594763e-11
LUSC	PLXNB2	ARHGEF12	-4.31287793286558	3.85129646231505e-08
LIHC	PLXNB2	ARHGEF12	-1.41507255727965	4.08456474127691e-05
KIRP	PLXNB2	ARHGEF12	-1.02134884587413	4.20957803726197e-07
PRAD	PLXNB2	MET	1.64643528857984	4.53264387257039e-06
KIRP	PLXNB2	MET	1.52040209913428	4.6566128730774e-10
LIHC	PLXNB2	RND3	-4.68514746510352	4.91907449309094e-09
BRCA	PLXNB2	SEMA3F	1.85124094372612	5.1639316957333e-15
LIHC	PLXNB2	ARHGEF11	-3.84984442030122	5.1965939338348e-08
LUAD	PLXNB2	SEMA3E	-1.09827969005927	6.23590787285683e-08
LIHC	PLXNB2	SEMA3F	-1.80378385104422	7.79049220721842e-10
KICH	PLXNB2	MET	1.18206250071648	8.34465026855468e-07
PRAD	PLXNB2	RRAS	-2.03094624890416	8.40517570249428e-09
LUSC	PLXNB2	SEMA4F	2.02755015850579	9.88885026766033e-06

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with PLXNB2

ARHGEF11, RND1, PTN, ARHGEF12, PLCG1, HMOX2, CENPU, PFDN1, C12orf57, TACC1, NIF3L1, FBXO6, CCDC8, RHOD, PVRIG, HLA-E, LMAN2, BTNL8, PTCH1, PTPRK, SIAE, LYPD6, NTRK1, TMX1, DEFA1, DEFA5, ST8SIA4, IL17RC, TMED6, SCGB1D1, ADAM21, TLR1, IL27RA, MPPE1, TMPRSS3, TRIM25, PTPRO, RNF4, GRB2, KIAA1429, VDAC2, VDAC3, APEX1, LMBR1L, FAM105A, PLEKHA4, E, M, nsp4, nsp6, ORF7a, ORF7b, ORF8, ST7, RET, FKBP8, SEC61B, E5a, E5b, DNAJC1, DNAJC25, ARF6, ATP2A1, CYP2C9, DERL1, DHFRL1, ELOVL5, EMD, HSD17B11, HSD3B7, KRAS, LAMP2, LAMP3, KIAA1715, LRRC59, LYN, MARCKS, METTL7A, RAB2A, RAB35, RAB5C, RAB9A, RPN1, RPN2, SEC62, SSR1, SMAD4, EDDM3B, LGALS1, PATE1, LY86, RNF149, SLC22A3, FBXO2, ZDHHC12, SEMA4C, SCGB2A1, KLRC1, CDHR3, C2CD4B, CRYZL1, C7orf34, CLEC12B, BTNL3, C1orf54, RLN1, CYHR1, APOA2, CD160, SERGEF, DEFB135, SPCS1, PIGH, TRGV3, BRICD5, ASIC4, IGLL5, SDF2L1, CST11, CLEC2B, IL5RA, DNASE1L1, SLURP1, TMEM106A, CNTNAP3, GGH, HLA-G, TSHR, ECEL1, SFTPC, CBLN4, BTNL2, DPP4, TMPRSS11B, TMPRSS4, TMPRSS2, TMEM106B,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
PLXNB2	chr22	50719833	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PLXNB2	chr22	50719860	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PLXNB2	chr22	50720295	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant,SO:0001627\|intron_variant	SO:0001819\|synonymous_variant,SO:0001627\|intron_variant
PLXNB2	chr22	50721296	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PLXNB2	chr22	50722277	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PLXNB2	chr22	50725640	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PLXNB2	chr22	50727512	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PLXNB2	chr22	50728168	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
PLXNB2	BLCA	chr22	50721182	50721182	T	G	Missense_Mutation	p.N982T	5
PLXNB2	SARC	chr22	50719043	50719043	G	A	Silent	p.F1350F	5
PLXNB2	SKCM	chr22	50719833	50719833	G	A	Silent	p.I1206I	5
PLXNB2	LUAD	chr22	50719028	50719028	C	A	Silent	p.T1355T	4
PLXNB2	BRCA	chr22	50719361	50719361	C	T	Missense_Mutation	p.E1269K	4
PLXNB2	BLCA	chr22	50719197	50719197	C	T	Silent	p.L1323L	4
PLXNB2	BLCA	chr22	50720089	50720089	G	A	Missense_Mutation	p.T1143M	4
PLXNB2	LUSC	chr22	50728775	50728775	G	A	Missense_Mutation	p.P80L	4
PLXNB2	PAAD	chr22	50720348	50720348	C	A	Missense_Mutation	p.D1094Y	3
PLXNB2	SKCM	chr22	50728628	50728628	G	A	Missense_Mutation	p.S129F	3
PLXNB2	KIRP	chr22	50728592	50728592	T	A	Missense_Mutation	p.K141M	3
PLXNB2	BRCA	chr22	50717396	50717396	C	T	Silent	p.P1478	3
PLXNB2	SKCM	chr22	50721178	50721178	G	A	Silent	p.P983P	3
PLXNB2	BLCA	chr22	50719219	50719220	-	G	Frame_Shift_Ins	p.L1316fs	3
PLXNB2	PAAD	chr22	50716129	50716129	G	C	Missense_Mutation	p.P1696R	3
PLXNB2	KIRP	chr22	50728593	50728593	T	C	Missense_Mutation	p.K141E	3
PLXNB2	BRCA	chr22	50719581	50719583	TCT	-	In_Frame_Del	p.K1233in_frame_del	3
PLXNB2	UCEC	chr22	50728596	50728596	C	T	Missense_Mutation	p.E140K	3
PLXNB2	COAD	chr22	50728062	50728062	T	C	Missense_Mutation	p.K318E	3
PLXNB2	BRCA	chr22	50720419	50720421	GTG	-	In_Frame_Del	p.T1070in_frame_del	3
PLXNB2	COAD	chr22	50721829	50721830	-	C	Frame_Shift_Ins	p.G872fs	3
PLXNB2	HNSC	chr22	50727541	50727541	C	T	Missense_Mutation	p.E367K	3
PLXNB2	BRCA	chr22	50727190	50727190	G	A	Silent	p.Y454	3
PLXNB2	UCEC	chr22	50728595	50728595	T	C	Missense_Mutation	p.E140G	3
PLXNB2	ESCA	chr22	50716391	50716391	C	T	Missense_Mutation	p.G1647R	3
PLXNB2	SKCM	chr22	50720628	50720628	G	A	Silent	p.S1034S	3
PLXNB2	THYM	chr22	50715077	50715077	T	A	Missense_Mutation	p.H1773L	3
PLXNB2	UCEC	chr22	50722588	50722588	C	T	Missense_Mutation	p.G746S	3
PLXNB2	SKCM	chr22	50716104	50716104	G	A	Silent	p.V1704V	3
PLXNB2	UCEC	chr22	50722387	50722387	C	T	Missense_Mutation	p.D766N	3
PLXNB2	CESC	chr22	50727976	50727976	G	A	Silent		3
PLXNB2	PAAD	chr22	50719911	50719911	G	A	Silent	p.R1180R	3
PLXNB2	UCS	chr22	50716562	50716562	C	T	Missense_Mutation	p.R1624Q	3
PLXNB2	UCEC	chr22	50728584	50728584	C	T	Missense_Mutation	p.V144M	3
PLXNB2	ACC	chr22	50722344	50722344	G	A	Missense_Mutation	p.A780V	3
PLXNB2	PAAD	chr22	50728347	50728347	C	T	Missense_Mutation	p.E223K	3
PLXNB2	ACC	chr22	50722601	50722601	G	A	Silent	p.Y741Y	3
PLXNB2	COAD	chr22	50725553	50725553	T	C	Silent	p.T583T	3
PLXNB2	PAAD	chr22	50728054	50728054	G	A	Silent	p.H320H	3
PLXNB2	ESCA	chr22	50727557	50727557	G	T	Missense_Mutation	p.S361R	2
PLXNB2	SARC	chr22	50717402	50717402	G	A	Silent		2
PLXNB2	BLCA	chr22	50718922	50718922	G	A	Missense_Mutation	p.R1391C	2
PLXNB2	CESC	chr22	50724236	50724236	G	A	Missense_Mutation		2
PLXNB2	BLCA	chr22	50727555	50727555	A	G	Missense_Mutation	p.F362S	2
PLXNB2	LIHC	chr22	50718092	50718092	C	-	Frame_Shift_Del	p.G1452fs	2
PLXNB2	LUAD	chr22	50724456	50724456	G	T	Nonsense_Mutation	p.S650*	2
PLXNB2	UCEC	chr22	50718188	50718188	G	A	Silent	p.P1420	2
PLXNB2	UCEC	chr22	50728216	50728216	G	T	Nonsense_Mutation	p.C266*	2
PLXNB2	PAAD	chr22	50717108	50717109	-	GGAGCCC	Frame_Shift_Ins	p.T1522fs	2
PLXNB2	SKCM	chr22	50728360	50728360	G	A	Silent	p.F218F	2
PLXNB2	HNSC	chr22	50728272	50728272	G	A	Missense_Mutation	p.R248C	2
PLXNB2	SKCM	chr22	50727178	50727178	C	G	Missense_Mutation	p.Q458H	2
PLXNB2	STAD	chr22	50722592	50722592	A	G	Silent	p.S744S	2
PLXNB2	BLCA	chr22	50722117	50722117	C	A	Missense_Mutation	p.L828F	2
PLXNB2	STAD	chr22	50716655	50716655	C	A	Missense_Mutation	p.R1593L	2
PLXNB2	THYM	chr22	50715077	50715077	T	A	Missense_Mutation		2
PLXNB2	CHOL	chr22	50720113	50720113	T	A	Missense_Mutation	p.E1135V	2
PLXNB2	PRAD	chr22	50720454	50720454	C	G	Silent	p.P1058P	2
PLXNB2	ESCA	chr22	50728029	50728029	C	T	Missense_Mutation	p.A329T	2
PLXNB2	SARC	chr22	50718148	50718148	T	C	Missense_Mutation		2
PLXNB2	CESC	chr22	50719806	50719806	C	A	Silent		2
PLXNB2	LIHC	chr22	50723034	50723034	C	-	Frame_Shift_Del	p.E717fs	2
PLXNB2	TGCT	chr22	50728449	50728449	C	A	Missense_Mutation		2
PLXNB2	UCEC	chr22	50719370	50719370	C	T	Missense_Mutation	p.D1266N	2
PLXNB2	ESCA	chr22	50728029	50728029	C	T	Missense_Mutation		2
PLXNB2	UCEC	chr22	50728516	50728516	G	A	Silent	p.R166	2
PLXNB2	HNSC	chr22	50720062	50720062	G	A	Missense_Mutation	p.P1152L	2
PLXNB2	SKCM	chr22	50719037	50719037	G	A	Silent	p.S1352S	2
PLXNB2	STAD	chr22	50728801	50728801	C	T	Silent	p.P71P	2
PLXNB2	STAD	chr22	50728968	50728968	C	T	Missense_Mutation	p.A16T	2
PLXNB2	COAD	chr22	50714395	50714395	G	-	Splice_Site	.	2
PLXNB2	COAD	chr22	50720622	50720622	C	T	Silent	p.Q1036Q	2
PLXNB2	ESCA	chr22	50728337	50728337	G	T	Missense_Mutation	p.P226H	2
PLXNB2	PAAD	chr22	50719911	50719911	G	A	Silent		2
PLXNB2	KICH	chr22	50720400	50720400	G	A	Silent	p.D1076D	2
PLXNB2	CESC	chr22	50719808	50719808	C	A	Missense_Mutation		2
PLXNB2	LIHC	chr22	50723048	50723048	G	-	Frame_Shift_Del	p.P712fs	2
PLXNB2	UCEC	chr22	50719533	50719533	T	C	Missense_Mutation	p.K1250E	2
PLXNB2	UCEC	chr22	50728645	50728645	G	A	Silent	p.R123	2
PLXNB2	SKCM	chr22	50724285	50724285	G	A	Missense_Mutation	p.P678S	2
PLXNB2	HNSC	chr22	50721196	50721196	G	C	Missense_Mutation	p.F977L	2
PLXNB2	SKCM	chr22	50720694	50720694	C	T	Silent	p.Q1012Q	2
PLXNB2	STAD	chr22	50728515	50728515	C	T	Missense_Mutation	p.V167M	2
PLXNB2	BLCA	chr22	50720031	50720031	C	G	Missense_Mutation	p.Q1162H	2
PLXNB2	STAD	chr22	50716155	50716155	C	T	Silent	p.R1687R	2
PLXNB2	CESC	chr22	50726395	50726395	G	C	Silent		2
PLXNB2	PAAD	chr22	50728054	50728054	G	A	Silent		2
PLXNB2	SKCM	chr22	50728070	50728070	G	A	Missense_Mutation	p.P315L	2
PLXNB2	UCEC	chr22	50719865	50719865	C	T	Missense_Mutation	p.V1196M	2
PLXNB2	PAAD	chr22	50728171	50728171	G	A	Silent	p.A281A	2
PLXNB2	HNSC	chr22	50719042	50719042	C	T	Missense_Mutation	p.A1351T	2
PLXNB2	SKCM	chr22	50720702	50720702	G	A	Silent	p.L1010L	2
PLXNB2	KIRP	chr22	50716444	50716444	T	C	Splice_Site	.	2
PLXNB2	HNSC	chr22	50720458	50720458	G	A	Missense_Mutation	p.S1057F	2
PLXNB2	STAD	chr22	50720088	50720088	C	A	Silent	p.T1143T	2
PLXNB2	STAD	chr22	50728019	50728019	G	-	Frame_Shift_Del	p.T332fs	2
PLXNB2	ESCA	chr22	50716282	50716282	C	T	Missense_Mutation	p.S1683N	2
PLXNB2	PAAD	chr22	50728347	50728347	C	T	Missense_Mutation		2
PLXNB2	SKCM	chr22	50728071	50728071	G	A	Missense_Mutation	p.P315S	2
PLXNB2	KIRC	chr22	50717397	50717397	G	A	Missense_Mutation	p.P1478L	2
PLXNB2	LUAD	chr22	50721832	50721832	C	T	Silent	p.G871G	2
PLXNB2	TGCT	chr22	50728449	50728449	C	A	Missense_Mutation	p.D189Y	2
PLXNB2	LUAD	chr22	50722093	50722093	C	T	Silent	p.Q836Q	2
PLXNB2	UCEC	chr22	50720611	50720624	GGACTGACCGTCAT	-	Frame_Shift_Del	p.M1038fs	2
PLXNB2	LUAD	chr22	50718982	50718982	T	-	Frame_Shift_Del	p.T1371fs	2
PLXNB2	SKCM	chr22	50717097	50717097	G	A	Silent	p.I1525I	2
PLXNB2	SKCM	chr22	50728408	50728408	G	A	Silent	p.D202D	2
PLXNB2	STAD	chr22	50728169	50728169	G	A	Missense_Mutation	p.A282V	2
PLXNB2	STAD	chr22	50728320	50728320	A	C	Missense_Mutation	p.F232V	2
PLXNB2	THYM	chr22	50719926	50719926	C	T	Silent	p.V1175V	2
PLXNB2	ESCA	chr22	50715316	50715316	A	-	Frame_Shift_Del	p.L1739fs	2
PLXNB2	CESC	chr22	50719908	50719908	C	T	Silent		2
PLXNB2	ESCA	chr22	50718132	50718132	G	A	Missense_Mutation	p.A1439V	2
PLXNB2	PAAD	chr22	50716129	50716129	G	C	Missense_Mutation		2
PLXNB2	SARC	chr22	50718148	50718148	T	C	Missense_Mutation	p.K1434E	2
PLXNB2	SKCM	chr22	50718106	50718106	G	A	Missense_Mutation	p.L1448F	2
PLXNB2	HNSC	chr22	50728422	50728422	C	T	Missense_Mutation	p.E198K	2
PLXNB2	SKCM	chr22	50717035	50717035	A	G	Missense_Mutation	p.M1546T	2
PLXNB2	LUAD	chr22	50728234	50728234	C	T	Silent	p.L260L	2
PLXNB2	UCEC	chr22	50721607	50721607	C	A	Missense_Mutation	p.K896N	2
PLXNB2	ESCA	chr22	50716391	50716391	C	T	Missense_Mutation		2
PLXNB2	SARC	chr22	50717058	50717058	C	T	Silent		2
PLXNB2	HNSC	chr22	50724643	50724643	G	C	Missense_Mutation	p.F612L	2
PLXNB2	LIHC	chr22	50720691	50720691	C	T	Silent		2
PLXNB2	STAD	chr22	50726198	50726198	C	T	Silent	p.P502P	2
PLXNB2	BRCA	chr22	50720382	50720382	G	A	Missense_Mutation	p.S100L	2
PLXNB2	CESC	chr22	50719913	50719913	G	A	Missense_Mutation		2
PLXNB2	ESCA	chr22	50722588	50722588	C	A	Missense_Mutation	p.G746C	2
PLXNB2	PAAD	chr22	50720348	50720348	C	A	Missense_Mutation		2
PLXNB2	SKCM	chr22	50722063	50722063	G	A	Silent	p.S846S	2
PLXNB2	KIRC	chr22	50728922	50728922	T	C	Missense_Mutation	p.E31G	2
PLXNB2	SKCM	chr22	50724519	50724519	G	A	Missense_Mutation	p.S629F	2
PLXNB2	BLCA	chr22	50714172	50714172	C	G	Missense_Mutation	p.Q1826H	2
PLXNB2	UCEC	chr22	50721777	50721777	A	C	Missense_Mutation	p.F890V	2
PLXNB2	ESCA	chr22	50716897	50716897	G	T	Missense_Mutation	p.P1567T	2
PLXNB2	SARC	chr22	50728062	50728062	T	C	Missense_Mutation		2
PLXNB2	HNSC	chr22	50727227	50727227	C	T	Missense_Mutation	p.R442H	2
PLXNB2	STAD	chr22	50714329	50714329	A	G	Missense_Mutation	p.Y1801H	2
PLXNB2	BLCA	chr22	50726223	50726223	C	A	Splice_Site		2
PLXNB2	STAD	chr22	50718980	50718980	C	T	Silent	p.T1371T	2
PLXNB2	BRCA	chr22	50722134	50722134	T	C	Missense_Mutation	p.I823V	2
PLXNB2	SKCM	chr22	50720717	50720717	C	T	Missense_Mutation	p.G1005S	2
PLXNB2	HNSC	chr22	50716358	50716358	A	G	Missense_Mutation	p.F1658L	2
PLXNB2	STAD	chr22	50727399	50727399	C	T	Missense_Mutation	p.R414Q	2
PLXNB2	BLCA	chr22	50717351	50717351	C	T	Silent	p.K1493K	2
PLXNB2	ESCA	chr22	50728477	50728477	G	A	Silent		2
PLXNB2	HNSC	chr22	50720046	50720046	C	T	Silent	p.P1157P	2
PLXNB2	STAD	chr22	50720370	50720370	G	A	Silent	p.A1086A	2
PLXNB2	STAD	chr22	50728614	50728614	A	T	Missense_Mutation	p.Y134N	2
PLXNB2	LUAD	chr22	50719226	50719226	G	A	Nonsense_Mutation	p.Q1314*	2
PLXNB2	CESC	chr22	50719367	50719367	C	T	Missense_Mutation		2
PLXNB2	COAD	chr22	50722408	50722408	T	C	Missense_Mutation	p.N759D	2
PLXNB2	UCEC	chr22	50723070	50723070	C	A	Missense_Mutation	p.D705Y	2
PLXNB2	HNSC	chr22	50716167	50716167	G	A	Silent		2
PLXNB2	SKCM	chr22	50720718	50720718	C	T	Silent	p.T1004T	2
PLXNB2	KIRC	chr22	50724518	50724518	G	T	Silent	p.S629S	2
PLXNB2	HNSC	chr22	50716420	50716420	T	C	Missense_Mutation	p.D1637G	2
PLXNB2	SKCM	chr22	50719308	50719308	G	A	Silent	p.F1286F	2
PLXNB2	THYM	chr22	50719926	50719926	C	T	Silent		2
PLXNB2	UCS	chr22	50719352	50719360	TGCCGGCCT	-	In_Frame_Del	p.EAGI1269del	2
PLXNB2	ESCA	chr22	50721802	50721803	CA	-	Frame_Shift_Del	p.L881fs	2
PLXNB2	HNSC	chr22	50718166	50718166	T	A	Missense_Mutation	p.I1428F	2
PLXNB2	LUAD	chr22	50721207	50721207	C	T	Missense_Mutation	p.G974S	2
PLXNB2	CESC	chr22	50728569	50728569	C	T	Missense_Mutation		2
PLXNB2	LUAD	chr22	50716158	50716158	G	A	Silent	p.L1686L	2
PLXNB2	ESCA	chr22	50728606	50728606	G	T	Missense_Mutation	p.D136E	2
PLXNB2	UCEC	chr22	50726405	50726405	G	A	Missense_Mutation	p.S481F	2
PLXNB2	BLCA	chr22	50721499	50721499	G	A	Silent	p.L932L	2
PLXNB2	HNSC	chr22	50724681	50724681	G	A	Nonsense_Mutation	p.R600*	2
PLXNB2	STAD	chr22	50718156	50718156	T	C	Missense_Mutation	p.Q1431R	2
PLXNB2	BLCA	chr22	50718455	50718455	G	C	Missense_Mutation	p.I1407M	2
PLXNB2	STAD	chr22	50716356	50716356	G	A	Silent	p.F1658F	2
PLXNB2	LIHC	chr22	50720691	50720691	C	T	Silent	p.R1013R	2
PLXNB2	LUAD	chr22	50716360	50716360	A	T	Missense_Mutation	p.F1657Y	2
PLXNB2	CESC	chr22	50719361	50719361	C	T	Missense_Mutation		2
PLXNB2	BLCA	chr22	50718479	50718479	C	A	Missense_Mutation	p.R1399S	2
PLXNB2	LIHC	chr22	50716867	50716867	C	-	Frame_Shift_Del	p.E1577fs	2
PLXNB2	UCEC	chr22	50714390	50714390	C	T	Silent	p.A1780	2
PLXNB2	CESC	chr22	50728569	50728569	C	T	Missense_Mutation	p.E149K	2
PLXNB2	UCEC	chr22	50727442	50727442	C	T	Missense_Mutation	p.E400K	2
PLXNB2	SKCM	chr22	50720043	50720043	G	A	Silent	p.P1158P	2
PLXNB2	KIRP	chr22	50719301	50719302	-	T	Frame_Shift_Ins	p.S1289fs	2
PLXNB2	HNSC	chr22	50716549	50716549	G	A	Silent	p.V1628V	2
PLXNB2	SKCM	chr22	50722577	50722577	G	A	Silent	p.I749I	2
PLXNB2	STAD	chr22	50717049	50717049	G	A	Silent	p.R1541R	2
PLXNB2	STAD	chr22	50715103	50715103	C	T	Silent	p.Q1764Q	2
PLXNB2	CHOL	chr22	50720113	50720113	T	A	Missense_Mutation		2
PLXNB2	OV	chr22	50724633	50724633	G	T	Missense_Mutation	p.R616S	1
PLXNB2	HNSC	chr22	50721196	50721196	G	C	Missense_Mutation		1
PLXNB2	SARC	chr22	50719043	50719043	G	A	Silent	p.F1350	1
PLXNB2	HNSC	chr22	50721260	50721260	C	T	Missense_Mutation	p.R956Q	1
PLXNB2	SKCM	chr22	50728538	50728538	G	A	Missense_Mutation	p.S159F	1
PLXNB2	LGG	chr22	50727510	50727510	T	A	Missense_Mutation	p.D377V	1
PLXNB2	BLCA	chr22	50720031	50720031	C	G	Missense_Mutation		1
PLXNB2	LIHC	chr22	50727540	50727540	T	C	Missense_Mutation	p.E367G	1
PLXNB2	STAD	chr22	50718488	50718489	CA	-	Frame_Shift_Del	p.V1397fs	1
PLXNB2	THYM	chr22	50719926	50719926	C	T	Silent	p.V1175	1
PLXNB2	COAD	chr22	50719251	50719251	A	G	Silent	p.P1305P	1
PLXNB2	ACC	chr22	50714236	50714236	A	T	Splice_Site	p.I1805_splice	1
PLXNB2	STAD	chr22	50728807	50728807	C	T	Silent		1
PLXNB2	CESC	chr22	50720141	50720141	G	A	Missense_Mutation		1
PLXNB2	COAD	chr22	50727184	50727184	C	T	Missense_Mutation	p.M456I	1
PLXNB2	ESCA	chr22	50721802	50721803	CA	-	Frame_Shift_Del		1
PLXNB2	HNSC	chr22	50720458	50720458	G	A	Missense_Mutation		1
PLXNB2	HNSC	chr22	50722576	50722576	C	T	Missense_Mutation	p.D750N	1
PLXNB2	KIRP	chr22	50722099	50722099	G	A	Silent	p.D834D	1
PLXNB2	SKCM	chr22	50728219	50728219	C	A	Missense_Mutation	p.Q265H	1
PLXNB2	KIRP	chr22	50716444	50716444	T	C	Splice_Site		1
PLXNB2	BLCA	chr22	50714172	50714172	C	G	Missense_Mutation		1
PLXNB2	LIHC	chr22	50726429	50726429	G	-	Frame_Shift_Del	p.P473fs	1
PLXNB2	DLBC	chr22	50720430	50720430	G	C	Silent	p.A1066A	1
PLXNB2	LUSC	chr22	50717382	50717382	T	A	Missense_Mutation	p.N1483I	1
PLXNB2	ESCA	chr22	50722580	50722589	ATTCTTGCCG	-	Frame_Shift_Del	p.746_749del	1
PLXNB2	OV	chr22	50721516	50721516	C	A	Missense_Mutation	p.D927Y	1
PLXNB2	HNSC	chr22	50720062	50720062	G	A	Missense_Mutation		1
PLXNB2	SARC	chr22	50717402	50717402	G	A	Silent	p.A1476	1
PLXNB2	KICH	chr22	50720400	50720400	G	A	Silent		1
PLXNB2	SKCM	chr22	50719321	50719321	T	C	Missense_Mutation	p.D1282G	1
PLXNB2	LGG	chr22	50727510	50727510	T	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50724633	50724633	G	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50716359	50716359	G	C	Missense_Mutation	p.F1657L	1
PLXNB2	LIHC	chr22	50719562	50719562	C	A	Missense_Mutation	p.G1240V	1
PLXNB2	STAD	chr22	50714358	50714358	A	G	Missense_Mutation	p.L1791P	1
PLXNB2	LUAD	chr22	50727191	50727191	T	G	Missense_Mutation	p.Y454S	1
PLXNB2	THYM	chr22	50722370	50722371	-	CGG	In_Frame_Ins	p.772in_frame_insR	1
PLXNB2	COAD	chr22	50720123	50720123	C	T	Missense_Mutation	p.V1132M	1
PLXNB2	BLCA	chr22	50728888	50728888	G	C	Silent		1
PLXNB2	LUAD	chr22	50716683	50716683	C	A	Nonsense_Mutation	p.E1584*	1
PLXNB2	CESC	chr22	50728603	50728603	G	G	Silent		1
PLXNB2	COAD	chr22	50727558	50727558	C	T	Missense_Mutation	p.S361N	1
PLXNB2	LUAD	chr22	50728917	50728917	C	A	Nonsense_Mutation	p.E33*	1
PLXNB2	HNSC	chr22	50721260	50721260	C	T	Missense_Mutation		1
PLXNB2	HNSC	chr22	50717426	50717426	G	A	Silent	p.I1468I	1
PLXNB2	SKCM	chr22	50728901	50728901	G	A	Missense_Mutation	p.A38V	1
PLXNB2	KIRP	chr22	50716686	50716686	C	A	Nonsense_Mutation		1
PLXNB2	BLCA	chr22	50721163	50721163	G	C	Missense_Mutation		1
PLXNB2	BLCA	chr22	50721224	50721224	G	T	Missense_Mutation	p.S968Y	1
PLXNB2	LIHC	chr22	50728224	50728224	G	-	Frame_Shift_Del	p.L264fs	1
PLXNB2	THYM	chr22	50722366	50722366	C	T	Missense_Mutation	p.A773T	1
PLXNB2	DLBC	chr22	50726134	50726134	C	T	Missense_Mutation	p.A524T	1
PLXNB2	LUSC	chr22	50719566	50719566	C	A	Nonsense_Mutation	p.E1239*	1
PLXNB2	ESCA	chr22	50722589	50722589	G	T	Nonsense_Mutation	p.Y745X	1
PLXNB2	PRAD	chr22	50716552	50716552	T	C	Silent	p.S1627S	1
PLXNB2	HNSC	chr22	50722091	50722091	C	G	Missense_Mutation		1
PLXNB2	SARC	chr22	50717058	50717058	C	T	Silent	p.R1538R	1
PLXNB2	SKCM	chr22	50719253	50719253	G	A	Missense_Mutation	p.P1305S	1
PLXNB2	BLCA	chr22	50719915	50719915	G	C	Missense_Mutation		1
PLXNB2	LIHC	chr22	50728375	50728379	GGTGG	-	Frame_Shift_Del	p.212_214del	1
PLXNB2	STAD	chr22	50717305	50717305	T	A	Missense_Mutation	p.R1509W	1
PLXNB2	LUAD	chr22	50724601	50724601	C	T	Splice_Site		1
PLXNB2	UCEC	chr22	50722121	50722121	T	C	Missense_Mutation	p.N827S	1
PLXNB2	BLCA	chr22	50727453	50727453	G	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50727979	50727979	G	A	Silent	p.F345F	1
PLXNB2	TGCT	chr22	50719062	50719062	G	T	Missense_Mutation		1
PLXNB2	LUAD	chr22	50720293	50720293	A	T	Missense_Mutation	p.I1112N	1
PLXNB2	CESC	chr22	50723062	50723062	G	G	Silent		1
PLXNB2	COAD	chr22	50728001	50728001	C	T	Missense_Mutation	p.R338H	1
PLXNB2	LUAD	chr22	50719902	50719902	C	A	Silent	p.V1183V	1
PLXNB2	ESCA	chr22	50722580	50722589	ATTCTTGCCG	-	Frame_Shift_Del		1
PLXNB2	HNSC	chr22	50727541	50727541	C	T	Missense_Mutation		1
PLXNB2	HNSC	chr22	50722091	50722091	C	G	Missense_Mutation	p.R837T	1
PLXNB2	SKCM	chr22	50722087	50722087	G	A	Silent	p.I838I	1
PLXNB2	KIRP	chr22	50728011	50728011	G	T	Silent		1
PLXNB2	BLCA	chr22	50717351	50717351	C	T	Silent		1
PLXNB2	LGG	chr22	50728700	50728700	G	A	Missense_Mutation		1
PLXNB2	LIHC	chr22	50728252	50728252	G	-	Frame_Shift_Del	p.P254fs	1
PLXNB2	THYM	chr22	50727274	50727274	G	T	Silent	p.S426S	1
PLXNB2	COAD	chr22	50716089	50716089	G	A	Silent	p.D1709D	1
PLXNB2	DLBC	chr22	50727961	50727961	G	A	Silent	p.C351C	1
PLXNB2	LUSC	chr22	50718176	50718176	G	A	Silent	p.L1424L	1
PLXNB2	ESCA	chr22	50728477	50728477	G	A	Silent	p.N179N	1
PLXNB2	PRAD	chr22	50716066	50716066	T	C	Missense_Mutation	p.Q1717R	1
PLXNB2	COAD	chr22	50721140	50721140	C	A	Missense_Mutation	p.S996I	1
PLXNB2	ESCA	chr22	50728477	50728477	G	A	Silent	p.N179	1
PLXNB2	HNSC	chr22	50724608	50724608	T	G	Missense_Mutation		1
PLXNB2	SARC	chr22	50717402	50717402	G	A	Silent	p.A1476A	1
PLXNB2	KICH	chr22	50726135	50726135	G	A	Silent	p.S523S	1
PLXNB2	SKCM	chr22	50724696	50724696	G	A	Nonsense_Mutation	p.Q595*	1
PLXNB2	BLCA	chr22	50724615	50724615	C	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50716386	50716399	GTGCCCAGGCGCCA	-	Frame_Shift_Del	p.LAPGH1644fs	1
PLXNB2	LIHC	chr22	50728381	50728387	CAGGTAG	-	Frame_Shift_Del	p.210_212del	1
PLXNB2	STAD	chr22	50718432	50718432	A	G	Splice_Site	p.K1414_splice	1
PLXNB2	LUAD	chr22	50716346	50716346	C	T	Missense_Mutation	p.D1662N	1
PLXNB2	BLCA	chr22	50721499	50721499	G	A	Silent		1
PLXNB2	BLCA	chr22	50720304	50720304	G	A	Silent	p.V1108V	1
PLXNB2	LIHC	chr22	50716909	50716909	C	-	Frame_Shift_Del	p.V1563fs	1
PLXNB2	TGCT	chr22	50722618	50722618	G	T	Missense_Mutation		1
PLXNB2	LUAD	chr22	50718193	50718193	C	A	Nonsense_Mutation	p.E1419*	1
PLXNB2	CESC	chr22	50724315	50724315	G	A	Nonsense_Mutation		1
PLXNB2	LUAD	chr22	50728156	50728156	C	T	Silent	p.A286A	1
PLXNB2	ESCA	chr22	50715316	50715316	A	-	Frame_Shift_Del		1
PLXNB2	UCS	chr22	50716562	50716562	C	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50718203	50718223	GTCCTGGAGTAACACGGAGGG	-	Splice_Site	p.1415_splice	1
PLXNB2	SKCM	chr22	50724696	50724696	G	A	Nonsense_Mutation	p.Q595X	1
PLXNB2	KIRP	chr22	50719554	50719554	C	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50722167	50722167	T	C	Missense_Mutation		1
PLXNB2	LGG	chr22	50719539	50719539	G	T	Missense_Mutation		1
PLXNB2	LIHC	chr22	50728375	50728379	GGTGG	-	Frame_Shift_Del	p.ST212fs	1
PLXNB2	THYM	chr22	50715327	50715327	G	T	Silent	p.P1735P	1
PLXNB2	COAD	chr22	50716157	50716157	G	A	Missense_Mutation	p.R1687W	1
PLXNB2	DLBC	chr22	50714348	50714348	G	A	Silent	p.L1794L	1
PLXNB2	MESO	chr22	50728928	50728928	C	A	Missense_Mutation		1
PLXNB2	ESCA	chr22	50722580	50722589	ATTCTTGCCG	-	Frame_Shift_Del	p.YGKN745fs	1
PLXNB2	READ	chr22	50714223	50714223	C	G	Missense_Mutation	p.L1809F	1
PLXNB2	CESC	chr22	50724634	50724639	GCAGTC	-	In_Frame_Del		1
PLXNB2	HNSC	chr22	50727227	50727227	C	T	Missense_Mutation		1
PLXNB2	HNSC	chr22	50724643	50724643	G	C	Missense_Mutation		1
PLXNB2	SKCM	chr22	50719920	50719920	G	A	Silent	p.F1177F	1
PLXNB2	BLCA	chr22	50714136	50714136	G	C	Silent		1
PLXNB2	BLCA	chr22	50727507	50727508	-	CGTCG	Frame_Shift_Ins	p.G378fs	1
PLXNB2	LIHC	chr22	50728375	50728387	GGTGGACAGGTAG	-	Frame_Shift_Del	p.210_214del	1
PLXNB2	STAD	chr22	50728599	50728599	C	T	Missense_Mutation	p.G139R	1
PLXNB2	UCEC	chr22	50728516	50728516	G	A	Silent	p.R166R	1
PLXNB2	BLCA	chr22	50718479	50718479	C	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50716925	50716925	G	A	Silent	p.I1557I	1
PLXNB2	LIHC	chr22	50720043	50720043	G	-	Frame_Shift_Del	p.P1158fs	1
PLXNB2	CESC	chr22	50719367	50719367	C	T	Missense_Mutation	p.V1267M	1
PLXNB2	COAD	chr22	50728359	50728359	C	T	Missense_Mutation	p.V219M	1
PLXNB2	ESCA	chr22	50727557	50727557	G	T	Missense_Mutation		1
PLXNB2	UCS	chr22	50728775	50728775	G	A	Missense_Mutation		1
PLXNB2	PAAD	chr22	50717108	50717109	-	GGAGCCC	Frame_Shift_Ins	p.S1522fs	1
PLXNB2	KIRP	chr22	50721158	50721158	G	A	Missense_Mutation	p.P990L	1
PLXNB2	STAD	chr22	50718488	50718489	CA	-	Frame_Shift_Del		1
PLXNB2	HNSC	chr22	50728802	50728802	G	A	Missense_Mutation	p.P71L	1
PLXNB2	KIRP	chr22	50721488	50721488	G	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50724680	50724680	C	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50728615	50728615	G	C	Missense_Mutation	p.F133L	1
PLXNB2	LIHC	chr22	50720443	50720443	T	C	Missense_Mutation		1
PLXNB2	LIHC	chr22	50728381	50728387	CAGGTAG	-	Frame_Shift_Del	p.GYL209fs	1
PLXNB2	COAD	chr22	50716167	50716167	G	A	Silent	p.S1683S	1
PLXNB2	MESO	chr22	50728785	50728786	-	-	Frame_Shift_Ins		1
PLXNB2	ESCA	chr22	50715316	50715316	A	-	Frame_Shift_Del	p.L1740fs	1
PLXNB2	READ	chr22	50720051	50720051	G	C	Missense_Mutation	p.P1156A	1
PLXNB2	STAD	chr22	50722294	50722294	T	C	Missense_Mutation	p.T797A	1
PLXNB2	LUAD	chr22	50720626	50720626	A	G	Missense_Mutation	p.L1035P	1
PLXNB2	COAD	chr22	50721851	50721851	G	A	Missense_Mutation	p.A865V	1
PLXNB2	HNSC	chr22	50728272	50728272	G	A	Missense_Mutation		1
PLXNB2	HNSC	chr22	50728802	50728802	G	A	Missense_Mutation		1
PLXNB2	KIRC	chr22	50720683	50720683	A	T	Missense_Mutation	p.M1016K	1
PLXNB2	SKCM	chr22	50719618	50719618	C	T	Splice_Site	p.W1221_splice	1
PLXNB2	BLCA	chr22	50717344	50717344	C	G	Missense_Mutation		1
PLXNB2	BLCA	chr22	50726223	50726223	C	A	Splice_Site	p.R494_splice	1
PLXNB2	LIHC	chr22	50718956	50718956	C	G	Missense_Mutation	p.Q1379H	1
PLXNB2	KIRP	chr22	50719301	50719302	-	T	Frame_Shift_Ins	p.Q1289fs	1
PLXNB2	STAD	chr22	50718156	50718156	T	C	Missense_Mutation		1
PLXNB2	BLCA	chr22	50719219	50719220	-	-	Frame_Shift_Ins		1
PLXNB2	LIHC	chr22	50721534	50721534	C	-	Frame_Shift_Del	p.D921fs	1
PLXNB2	THCA	chr22	50721510	50721510	G	A	Missense_Mutation		1
PLXNB2	CESC	chr22	50719806	50719806	C	A	Silent	p.V1215	1
PLXNB2	COAD	chr22	50728405	50728405	G	A	Silent	p.H203H	1
PLXNB2	COAD	chr22	50728947	50728947	G	A	Missense_Mutation	p.R23C	1
PLXNB2	LUAD	chr22	50724601	50724601	C	T	Splice_Site	p.P626_splice	1
PLXNB2	UCS	chr22	50719352	50719360	TGCCGGCCT	-	In_Frame_Del		1
PLXNB2	PAAD	chr22	50728215	50728215	G	A	Missense_Mutation	p.R267W	1
PLXNB2	MESO	chr22	50720356	50720356	T	G	Missense_Mutation		1
PLXNB2	ESCA	chr22	50717349	50717349	A	-	Frame_Shift_Del	p.I1495fs	1
PLXNB2	KIRP	chr22	50717068	50717068	C	A	Missense_Mutation		1
PLXNB2	STAD	chr22	50718432	50718432	A	G	Splice_Site	.	1
PLXNB2	BLCA	chr22	50718455	50718455	G	C	Missense_Mutation		1
PLXNB2	BLCA	chr22	50719915	50719915	G	C	Missense_Mutation	p.S1179C	1
PLXNB2	LIHC	chr22	50721222	50721234	GGGACCCCCCGTA	-	Frame_Shift_Del	p.YGGSP965fs	1
PLXNB2	COAD	chr22	50716674	50716674	G	A	Missense_Mutation	p.R1587W	1
PLXNB2	LIHC	chr22	50722376	50722376	C	G	Silent	p.L769L	1
PLXNB2	STAD	chr22	50718919	50718919	T	C	Missense_Mutation	p.R1392G	1
PLXNB2	LUAD	chr22	50728108	50728108	C	A	Silent	p.R302R	1
PLXNB2	COAD	chr22	50722077	50722077	C	T	Missense_Mutation	p.G842S	1
PLXNB2	HNSC	chr22	50716549	50716549	G	A	Silent		1
PLXNB2	SARC	chr22	50728652	50728652	G	T	Missense_Mutation	p.A121D	1
PLXNB2	HNSC	chr22	50717426	50717426	G	A	Silent		1
PLXNB2	SKCM	chr22	50727255	50727255	G	A	Missense_Mutation	p.L433F	1
PLXNB2	BLCA	chr22	50720409	50720409	G	A	Silent		1
PLXNB2	HNSC	chr22	50719804	50719804	G	T	Missense_Mutation	p.S1216Y	1
PLXNB2	KIRP	chr22	50716444	50716444	T	C	Splice_Site	p.G1630_splice	1
PLXNB2	STAD	chr22	50727399	50727399	C	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50727555	50727555	A	G	Missense_Mutation		1
PLXNB2	LIHC	chr22	50720047	50720047	G	-	Frame_Shift_Del	p.P1158fs	1
PLXNB2	THCA	chr22	50727260	50727260	G	C	Missense_Mutation		1
PLXNB2	LUAD	chr22	50716156	50716156	C	A	Missense_Mutation	p.R1687L	1
PLXNB2	CESC	chr22	50719808	50719808	C	A	Missense_Mutation	p.V1215L	1
PLXNB2	COAD	chr22	50728600	50728600	G	A	Silent	p.S138S	1
PLXNB2	COAD	chr22	50728969	50728969	G	A	Silent	p.G15G	1
PLXNB2	ESCA	chr22	50716897	50716897	G	T	Missense_Mutation		1
PLXNB2	UCS	chr22	50719352	50719360	TGCCGGCCT	-	In_Frame_Del	p.1269_1272del	1
PLXNB2	PAAD	chr22	50728171	50728171	G	A	Silent		1
PLXNB2	MESO	chr22	50720356	50720356	T	G	Missense_Mutation	p.Y1091S	1
PLXNB2	GBM	chr22	50719359	50719359	C	T	Silent	p.E1269E	1
PLXNB2	LGG	chr22	50728700	50728700	G	A	Missense_Mutation	p.P105L	1
PLXNB2	BLCA	chr22	50724615	50724615	C	T	Missense_Mutation	p.E622K	1
PLXNB2	LIHC	chr22	50728375	50728379	GGTGG	-	Frame_Shift_Del		1
PLXNB2	LIHC	chr22	50716387	50716387	T	C	Missense_Mutation		1
PLXNB2	THYM	chr22	50722370	50722371	-	CGG	In_Frame_Ins	p.R771delinsRR	1
PLXNB2	COAD	chr22	50717344	50717344	C	T	Missense_Mutation	p.D1496N	1
PLXNB2	LIHC	chr22	50720335	50720335	T	C	Missense_Mutation	p.E1098G	1
PLXNB2	STAD	chr22	50718147	50718147	T	-	Frame_Shift_Del	p.K1434fs	1
PLXNB2	LUAD	chr22	50728577	50728577	C	A	Missense_Mutation	p.S146I	1
PLXNB2	COAD	chr22	50722392	50722392	C	T	Missense_Mutation	p.R764H	1
PLXNB2	ESCA	chr22	50722589	50722589	G	T	Nonsense_Mutation	p.Y745*	1
PLXNB2	HNSC	chr22	50721810	50721810	C	A	Missense_Mutation		1
PLXNB2	SARC	chr22	50728865	50728865	G	T	Missense_Mutation		1
PLXNB2	HNSC	chr22	50716358	50716358	A	G	Missense_Mutation		1
PLXNB2	KIRC	chr22	50726149	50726149	C	T	Missense_Mutation	p.V519M	1
PLXNB2	SKCM	chr22	50719522	50719522	G	A	Silent	p.F1253F	1
PLXNB2	BLCA	chr22	50728888	50728888	G	C	Silent	p.A42A	1
PLXNB2	SKCM	chr22	50718203	50718223	GTCCTGGAGTAACACGGAGGG	-	Frame_Shift_Del	p.1415_1416del	1
PLXNB2	KIRP	chr22	50719301	50719302	-	T	Frame_Shift_Ins	p.P1288fs	1
PLXNB2	BLCA	chr22	50719197	50719197	C	T	Silent		1
PLXNB2	LIHC	chr22	50721830	50721830	C	-	Frame_Shift_Del	p.G872fs	1
PLXNB2	THCA	chr22	50727260	50727260	G	C	Missense_Mutation	p.S431C	1
PLXNB2	LUAD	chr22	50715320	50715320	T	C	Missense_Mutation	p.K1738E	1
PLXNB2	CESC	chr22	50719913	50719913	G	A	Missense_Mutation	p.R1180C	1
PLXNB2	COAD	chr22	50728611	50728611	C	T	Missense_Mutation	p.E135K	1
PLXNB2	DLBC	chr22	50728063	50728063	G	A	Silent	p.D317D	1
PLXNB2	LUSC	chr22	50724256	50724256	G	A	Silent	p.F687F	1
PLXNB2	PRAD	chr22	50713409	50713409	A	G	Splice_Site	.	1
PLXNB2	ESCA	chr22	50717349	50717349	A	-	Frame_Shift_Del	p.I1494fs	1
PLXNB2	MESO	chr22	50728785	50728786	-	CTTG	Frame_Shift_Ins	p.KV76fs	1
PLXNB2	GBM	chr22	50717405	50717405	G	A	Silent	p.D1475D	1
PLXNB2	SARC	chr22	50728652	50728652	G	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50719895	50719895	G	A	Missense_Mutation	p.R1186C	1
PLXNB2	LGG	chr22	50719202	50719202	G	T	Missense_Mutation	p.L1322M	1
PLXNB2	BLCA	chr22	50721825	50721825	C	G	Missense_Mutation		1
PLXNB2	BLCA	chr22	50728767	50728767	C	T	Missense_Mutation	p.E83K	1
PLXNB2	LIHC	chr22	50728381	50728387	CAGGTAG	-	Frame_Shift_Del		1
PLXNB2	THYM	chr22	50728600	50728600	G	T	Missense_Mutation	p.S138R	1
PLXNB2	CESC	chr22	50728848	50728848	G	T	Missense_Mutation		1
PLXNB2	COAD	chr22	50717350	50717352	TCT	-	In_Frame_Del	p.1493_1494del	1
PLXNB2	LIHC	chr22	50727197	50727197	C	A	Missense_Mutation	p.S452I	1
PLXNB2	STAD	chr22	50721871	50721872	-	GAA	In_Frame_Ins	p.V859S	1
PLXNB2	LUAD	chr22	50727272	50727272	G	A	Missense_Mutation	p.S427L	1
PLXNB2	ESCA	chr22	50728207	50728207	G	T	Silent	p.P269	1
PLXNB2	PAAD	chr22	50726164	50726164	G	A	Nonsense_Mutation	p.R514X	1
PLXNB2	HNSC	chr22	50718166	50718166	T	A	Missense_Mutation		1
PLXNB2	SARC	chr22	50720051	50720051	G	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50719185	50719185	A	C	Silent	p.S1327S	1
PLXNB2	BLCA	chr22	50727453	50727453	G	A	Missense_Mutation	p.T396M	1
PLXNB2	KIRP	chr22	50728592	50728592	T	A	Missense_Mutation		1
PLXNB2	STAD	chr22	50718488	50718489	CA	-	Frame_Shift_Del	p.1396_1397del	1
PLXNB2	BLCA	chr22	50720304	50720304	G	A	Silent		1
PLXNB2	BLCA	chr22	50724680	50724680	C	T	Missense_Mutation	p.R600Q	1
PLXNB2	LIHC	chr22	50723075	50723075	C	-	Frame_Shift_Del	p.G703fs	1
PLXNB2	LUAD	chr22	50720743	50720743	C	A	Splice_Site		1
PLXNB2	CESC	chr22	50724315	50724315	G	A	Nonsense_Mutation	p.Q668*	1
PLXNB2	COAD	chr22	50728923	50728923	C	T	Missense_Mutation	p.E31K	1
PLXNB2	DLBC	chr22	50720155	50720155	T	A	Missense_Mutation	p.K1121M	1
PLXNB2	LUSC	chr22	50728004	50728004	G	A	Missense_Mutation	p.A337V	1
PLXNB2	ESCA	chr22	50721266	50721266	G	T	Missense_Mutation	p.A954E	1
PLXNB2	PRAD	chr22	50716563	50716563	G	A	Missense_Mutation	p.R1624W	1
PLXNB2	OV	chr22	49063285	49063285	G	C	Missense_Mutation		1
PLXNB2	GBM	chr22	50717405	50717405	G	A	Silent		1
PLXNB2	SARC	chr22	50721843	50721843	G	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50724456	50724456	G	A	Missense_Mutation	p.S650L	1
PLXNB2	LGG	chr22	50718975	50718975	A	T	Missense_Mutation	p.F1373Y	1
PLXNB2	BLCA	chr22	50722117	50722117	C	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50717344	50717344	C	G	Missense_Mutation	p.D1496H	1
PLXNB2	LIHC	chr22	50721222	50721234	GGGACCCCCCGTA	-	Frame_Shift_Del		1
PLXNB2	STAD	chr22	50722306	50722306	G	A	Silent	p.L793L	1
PLXNB2	THYM	chr22	50722370	50722371	-	CGG	In_Frame_Ins	p.771_771R>PG	1
PLXNB2	COAD	chr22	50719059	50719059	C	T	Missense_Mutation	p.R1345H	1
PLXNB2	LIHC	chr22	50718110	50718110	G	T	Nonsense_Mutation	p.Y1446*	1
PLXNB2	STAD	chr22	50721830	50721831	-	C	Frame_Shift_Ins	p.G872fs	1
PLXNB2	UCEC	chr22	50721549	50721549	G	T	Missense_Mutation	p.H916N	1
PLXNB2	CESC	chr22	50717414	50717414	C	A	Missense_Mutation		1
PLXNB2	COAD	chr22	50724512	50724512	C	A	Silent	p.V631V	1
PLXNB2	HNSC	chr22	50720046	50720046	C	T	Silent		1
PLXNB2	SARC	chr22	50717058	50717058	C	T	Silent	p.R1538	1
PLXNB2	HNSC	chr22	50722576	50722576	C	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50719572	50719572	G	A	Nonsense_Mutation	p.Q1237X	1
PLXNB2	KIRC	chr22	50728367	50728370	TGTG	-	Frame_Shift_Del	p.TQ215fs	1
PLXNB2	SKCM	chr22	50719572	50719572	G	A	Nonsense_Mutation	p.Q1237*	1
PLXNB2	KIRP	chr22	50728593	50728593	T	C	Missense_Mutation		1
PLXNB2	BLCA	chr22	50716386	50716399	GTGCCCAGGCGCCA	-	Frame_Shift_Del		1
PLXNB2	LIHC	chr22	50724294	50724294	G	-	Frame_Shift_Del	p.L675fs	1
PLXNB2	THYM	chr22	50715327	50715327	G	T	Silent		1
PLXNB2	LUAD	chr22	50714334	50714334	T	A	Missense_Mutation	p.Q1799L	1
PLXNB2	CESC	chr22	50726395	50726395	G	C	Silent	p.P484	1
PLXNB2	DLBC	chr22	50718941	50718941	C	T	Silent	p.K1384K	1
PLXNB2	LUSC	chr22	50714336	50714336	C	T	Silent	p.T1798T	1
PLXNB2	ESCA	chr22	50721802	50721803	CA	-	Frame_Shift_Del	p.881_882del	1
PLXNB2	PRAD	chr22	50720614	50720614	G	A	Splice_Site	p.T1039_splice	1
PLXNB2	ESCA	chr22	50726368	50726371	TCCC	-	Frame_Shift_Del	p.E492fs	1
PLXNB2	OV	chr22	50724253	50724253	C	T	Silent	p.Q688Q	1
PLXNB2	GBM	chr22	50719359	50719359	C	T	Missense_Mutation		1
PLXNB2	SARC	chr22	50719043	50719043	G	A	Silent		1
PLXNB2	HNSC	chr22	50718104	50718104	G	C	Silent	p.L1448L	1
PLXNB2	SKCM	chr22	50722331	50722331	G	A	Silent	p.G784G	1
PLXNB2	LGG	chr22	50722625	50722625	G	A	Silent	p.N733N	1
PLXNB2	BLCA	chr22	50721224	50721224	G	T	Missense_Mutation		1
PLXNB2	BLCA	chr22	50719851	50719851	G	A	Silent	p.L1200L	1
PLXNB2	STAD	chr22	50720152	50720152	G	A	Missense_Mutation	p.A1122V	1
PLXNB2	THYM	chr22	50721178	50721178	G	C	Silent	p.P983	1
PLXNB2	COAD	chr22	50719207	50719207	G	A	Missense_Mutation	p.S1320F	1
PLXNB2	STAD	chr22	50720152	50720152	G	A	Missense_Mutation		1
PLXNB2	LUAD	chr22	50720417	50720417	C	A	Missense_Mutation	p.V1071L	1
PLXNB2	ESCA	chr22	50728337	50728337	G	T	Missense_Mutation		1
PLXNB2	HNSC	chr22	50716420	50716420	T	C	Missense_Mutation		1
PLXNB2	HNSC	chr22	50719804	50719804	G	T	Missense_Mutation		1
PLXNB2	SKCM	chr22	50716154	50716154	A	G	Missense_Mutation	p.F1688L	1
PLXNB2	ACC	chr22	50720456	50720456	G	A	Missense_Mutation	p.P1058S	1
PLXNB2	KIRP	chr22	50721300	50721300	C	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50720089	50720089	G	A	Missense_Mutation		1
PLXNB2	BLCA	chr22	50721825	50721825	C	G	Missense_Mutation	p.E874Q	1
PLXNB2	LIHC	chr22	50718187	50718187	G	-	Frame_Shift_Del	p.L1421fs	1
PLXNB2	THYM	chr22	50721178	50721178	G	C	Silent		1
PLXNB2	LUAD	chr22	50719544	50719544	C	T	Missense_Mutation	p.R1246Q	1
PLXNB2	DLBC	chr22	50716068	50716068	C	T	Silent	p.A1716A	1
PLXNB2	LUSC	chr22	50720445	50720445	A	C	Silent	p.P1061P	1
PLXNB2	ESCA	chr22	50728207	50728207	G	T	Silent	p.P269P	1
PLXNB2	PRAD	chr22	50728217	50728217	C	T	Missense_Mutation	p.C266Y	1

Copy number variation (CNV) of PLXNB2
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across PLXNB2
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
95424	ESCA	TCGA-IG-A97H	CPSF6	chr12	69656342	+	PLXNB2	chr22	50727571	-
95424	N/A	BF087400	KRT7	chr12	52638511	+	PLXNB2	chr22	50713901	-
98934	N/A	EC558010	PLXNB2	chr22	50734803	-	DARS	chr2	136664836	+
102928	READ	TCGA-F5-6814	PLXNB2	chr22	50733148	-	DENND6B	chr22	50757432	-
100995	BRCA	TCGA-AN-A0FV-01A	PLXNB2	chr22	50733148	-	DLG2	chr11	83691685	-
89789	KIRP	TCGA-P4-A5EB	PLXNB2	chr22	50722030	-	MAST4	chr5	66195778	+
89789	KIRP	TCGA-P4-A5EB-01A	PLXNB2	chr22	50722031	-	MAST4	chr5	66195779	+
92253	N/A	AA984189	PLXNB2	chr22	50723783	-	MERTK	chr2	112783070	-
81726	KIRC	TCGA-CZ-5460-01A	PLXNB2	chr22	50724229	-	NDUFA4L2	chr12	57631118	-
70674	N/A	AV688404	PLXNB2	chr22	50713413	-	NKAIN1	chr1	31685909	-
86557	PRAD	TCGA-J9-A52B-01A	PLXNB2	chr22	50713408	-	P4HTM	chr3	49038871	+
66578	N/A	AA532612	PLXNB2	chr22	50713408	-	PAK6	chr15	40536625	-
95424	N/A	BI033029	PLXNB2	chr22	50730363	+	PLXNB2	chr22	50730429	-
81444	STAD	TCGA-BR-7722-01A	PLXNB2	chr22	50724229	-	PRMT1	chr19	50191419	+
101174	N/A	BM979599	PLXNB2	chr22	50713472	+	RBM25	chr14	73586932	-
80746	STAD	TCGA-BR-A4PE-01A	PLXNB2	chr22	50745982	-	RPL23	chr17	37008985	-
66578	LGG	TCGA-TM-A84J	PLXNB2	chr22	50721479	-	SMPD4P1	chr22	20968022	-
66578	LGG	TCGA-TM-A84J-01A	PLXNB2	chr22	50721766	-	SMPD4P1	chr22	20968022	-
98981	CESC	TCGA-VS-A9V0-01A	PLXNB2	chr22	50718434	-	ST3GAL1	chr8	134511432	-
98320	LUAD	TCGA-55-7913-01B	PLXNB2	chr22	50713408	-	SUPT16H	chr14	21829491	-
66578	UCEC	TCGA-AJ-A3EM	PLXNB2	chr22	50733147	-	TMPRSS6	chr22	37499458	-
66578	UCEC	TCGA-AJ-A3EM-01A	PLXNB2	chr22	50733148	-	TMPRSS6	chr22	37499458	-
66578	UCEC	TCGA-AJ-A3EM-01A	PLXNB2	chr22	50745982	-	TMPRSS6	chr22	37499458	-
102670	N/A	AI492115	PLXNB2	chr22	50713479	+	TRIM25	chr17	54990919	+
99580	LUAD	TCGA-75-7031-01A	PLXNB2	chr22	50713408	-	UTRN	chr6	144665237	+
95424	STAD	TCGA-BR-A4PD-01A	RNF213	chr17	78354727	+	PLXNB2	chr22	50721195	-
95424	BRCA	TCGA-AR-A1AQ-01A	SBF1	chr22	50899952	-	PLXNB2	chr22	50723094	-
95424	BRCA	TCGA-E2-A1L7-01A	SHANK3	chr22	51160865	+	PLXNB2	chr22	50733207	-
95424	BRCA	TCGA-E2-A1L7-01A	SHANK3	chr22	51160865	-	PLXNB2	chr22	50729026	-
95424	N/A	AI964040	TACC1	chr8	38710310	-	PLXNB2	chr22	50728748	+
95424	HNSC	TCGA-BA-A4IF	TAF9	chr5	68665483	-	PLXNB2	chr22	50717440	-
95425	OV	TCGA-13-1403	TUBGCP6	chr22	50678632	-	PLXNB2	chr22	50723094	-
95425	OV	TCGA-13-1403-01A	TUBGCP6	chr22	50678633	-	PLXNB2	chr22	50723094	-
95425	UCEC	TCGA-EO-A22X-01A	TUBGCP6	chr22	50682148	-	PLXNB2	chr22	50723094	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
TGCT	PLXNB2	0.00126095983361846	0.035
LUAD	PLXNB2	0.0137689697084492	0.37
BRCA	PLXNB2	0.0174544843332866	0.45

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	PLXNB2	0.0396898148940791	1
LUSC	PLXNB2	0.000635047486340152	0.021
GBM	PLXNB2	0.00791824248517245	0.23
LGG	PLXNB2	0.00233591044930948	0.072
LAML	PLXNB2	0.00836055687301263	0.23
ESCA	PLXNB2	0.023773401559122	0.64
THYM	PLXNB2	0.00155152420133988	0.05
SARC	PLXNB2	0.00341184287880242	0.1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source