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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: TNRC6A (NCBI Gene ID:27327)

Gene Summary

Gene Summary

Gene Information	Gene Name: TNRC6A
	Gene ID: 27327
	Gene Symbol	TNRC6A
	Gene ID	27327
	Gene Name	trinucleotide repeat containing adaptor 6A
	Synonyms	CAGH26\|FAME6\|GW1\|GW182\|TNRC6
	Cytomap	16p12.1
	Type of Gene	protein-coding
	Description	trinucleotide repeat-containing gene 6A proteinCAG repeat protein 26CTD-2540M10.1EDIEEMSY interactor proteinGW182 autoantigenglycine-tryptophan protein of 182 kDatrinucleotide repeat containing 6A
	Modification date	20200313
	UniProtAcc	Q8NDV7

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0017148	Negative regulation of translation
GO:0006417	Regulation of translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	TNRC6A	GO:0035278	miRNA mediated inhibition of translation	17671087

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
TNRC6A	(355.7 - 733]

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Translation Studies in PubMed

We searched PubMed using 'TNRC6A[title] AND translation [title] AND human.'

Gene	Title	PMID
TNRC6A	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000395799	24741573	24741621	In-frame
ENST00000395799	24762046	24762134	Frame-shift
ENST00000395799	24769659	24769681	Frame-shift
ENST00000395799	24788253	24788679	In-frame
ENST00000395799	24804793	24804970	In-frame
ENST00000395799	24807227	24807260	In-frame
ENST00000395799	24816025	24816172	In-frame
ENST00000395799	24826467	24826626	In-frame
ENST00000395799	24829913	24830021	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000395799	24741573	24741621	8455	135	182	1962	2	17
ENST00000395799	24788253	24788679	8455	293	718	1962	54	196
ENST00000395799	24804793	24804970	8455	3305	3481	1962	1058	1117
ENST00000395799	24816025	24816172	8455	3967	4113	1962	1279	1328
ENST00000395799	24826467	24826626	8455	4802	4960	1962	1557	1610
ENST00000395799	24829913	24830021	8455	5102	5209	1962	1657	1693

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
BRCA	TNRC6A	-1.24656754002514	3.76762765813611e-06

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
LUAD	TNRC6A	3	2	0.0321023617316507	0.615448125	0.521751562500001	-0.257838531018361	-0.439792001167661

Translation factor expression regulation through copy number variation of Translation factor

Cancer type

Gene

Coefficient

Pvalue

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with TNRC6A (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	TNRC6A	PIK3C2A	0.800229619	8.81E-12
DLBC	Cell metabolism gene	TNRC6A	CREBBP	0.822793756	7.26E-13
DLBC	Cell metabolism gene	TNRC6A	EP300	0.829429005	3.25E-13
DLBC	Cell metabolism gene	TNRC6A	SMG1	0.876499018	3.30E-16
DLBC	CGC	TNRC6A	ARID1A	0.806135372	4.73E-12
DLBC	CGC	TNRC6A	TRIM33	0.812088013	2.47E-12
DLBC	CGC	TNRC6A	SETD1B	0.817001747	1.42E-12
DLBC	CGC	TNRC6A	SPEN	0.819464916	1.07E-12
DLBC	CGC	TNRC6A	AFF4	0.82271246	7.33E-13
DLBC	CGC	TNRC6A	CREBBP	0.822793756	7.26E-13
DLBC	CGC	TNRC6A	BIRC6	0.826088049	4.89E-13
DLBC	CGC	TNRC6A	ATRX	0.827454702	4.15E-13
DLBC	CGC	TNRC6A	EP300	0.829429005	3.25E-13
DLBC	CGC	TNRC6A	ERCC4	0.831814679	2.42E-13
DLBC	CGC	TNRC6A	TRRAP	0.837147312	1.23E-13
DLBC	CGC	TNRC6A	ARID2	0.838706481	1.00E-13
DLBC	CGC	TNRC6A	NSD1	0.875424882	3.98E-16
DLBC	Epifactor	TNRC6A	ATXN7	0.803585515	6.20E-12
DLBC	Epifactor	TNRC6A	SETD5	0.803967219	5.96E-12
DLBC	Epifactor	TNRC6A	ARID1A	0.806135372	4.73E-12
DLBC	Epifactor	TNRC6A	BPTF	0.806813692	4.40E-12
DLBC	Epifactor	TNRC6A	CHD9	0.8095644	3.26E-12
DLBC	Epifactor	TNRC6A	CHD6	0.810656266	2.90E-12
DLBC	Epifactor	TNRC6A	TRIM33	0.812088013	2.47E-12
DLBC	Epifactor	TNRC6A	TAF1	0.812357282	2.40E-12
DLBC	Epifactor	TNRC6A	SRCAP	0.814472353	1.89E-12
DLBC	Epifactor	TNRC6A	SETD1B	0.817001747	1.42E-12
DLBC	Epifactor	TNRC6A	SPEN	0.819464916	1.07E-12
DLBC	Epifactor	TNRC6A	CREBBP	0.822793756	7.26E-13
DLBC	Epifactor	TNRC6A	ATRX	0.827454702	4.15E-13
DLBC	Epifactor	TNRC6A	EP300	0.829429005	3.25E-13
DLBC	Epifactor	TNRC6A	NIPBL	0.835862097	1.45E-13
DLBC	Epifactor	TNRC6A	TRRAP	0.837147312	1.23E-13
DLBC	Epifactor	TNRC6A	ARID2	0.838706481	1.00E-13
DLBC	Epifactor	TNRC6A	ASH1L	0.866027606	1.91E-15
DLBC	Epifactor	TNRC6A	NSD1	0.875424882	3.98E-16
DLBC	IUPHAR	TNRC6A	PIK3C2A	0.800229619	8.81E-12
DLBC	IUPHAR	TNRC6A	BPTF	0.806813692	4.40E-12
DLBC	IUPHAR	TNRC6A	TRIM33	0.812088013	2.47E-12
DLBC	IUPHAR	TNRC6A	TAF1	0.812357282	2.40E-12
DLBC	IUPHAR	TNRC6A	SETD1B	0.817001747	1.42E-12
DLBC	IUPHAR	TNRC6A	CREBBP	0.822793756	7.26E-13
DLBC	IUPHAR	TNRC6A	BIRC6	0.826088049	4.89E-13
DLBC	IUPHAR	TNRC6A	EP300	0.829429005	3.25E-13
DLBC	IUPHAR	TNRC6A	PDPK1	0.834023405	1.83E-13
DLBC	IUPHAR	TNRC6A	TRRAP	0.837147312	1.23E-13
DLBC	IUPHAR	TNRC6A	ASH1L	0.866027606	1.91E-15
DLBC	IUPHAR	TNRC6A	NSD1	0.875424882	3.98E-16
DLBC	IUPHAR	TNRC6A	SMG1	0.876499018	3.30E-16
DLBC	Kinase	TNRC6A	TRIM33	0.812088013	2.47E-12
DLBC	Kinase	TNRC6A	TAF1	0.812357282	2.40E-12
DLBC	Kinase	TNRC6A	PDPK1	0.834023405	1.83E-13
DLBC	Kinase	TNRC6A	TRRAP	0.837147312	1.23E-13
DLBC	Kinase	TNRC6A	SMG1	0.876499018	3.30E-16
DLBC	TF	TNRC6A	ZNF236	0.801984529	7.34E-12
DLBC	TF	TNRC6A	BPTF	0.806813692	4.40E-12
DLBC	TF	TNRC6A	SRCAP	0.814472353	1.89E-12
DLBC	TF	TNRC6A	SPEN	0.819464916	1.07E-12
DLBC	TF	TNRC6A	ZSCAN29	0.823089025	7.01E-13
DLBC	TF	TNRC6A	ZKSCAN1	0.830360068	2.90E-13
DLBC	TF	TNRC6A	ARID2	0.838706481	1.00E-13
DLBC	TF	TNRC6A	FOXJ3	0.850938561	1.87E-14
DLBC	TF	TNRC6A	ASH1L	0.866027606	1.91E-15
DLBC	TSG	TNRC6A	DIDO1	0.804879764	5.41E-12
DLBC	TSG	TNRC6A	ARID1A	0.806135372	4.73E-12
DLBC	TSG	TNRC6A	CREBBP	0.822793756	7.26E-13
DLBC	TSG	TNRC6A	ARID2	0.838706481	1.00E-13
GBM	Cell metabolism gene	TNRC6A	SMG1	0.810845446	2.11E-41
GBM	CGC	TNRC6A	CHD2	0.821418074	2.58E-43
GBM	Epifactor	TNRC6A	POGZ	0.818262998	9.90E-43
GBM	Epifactor	TNRC6A	CHD2	0.821418074	2.58E-43
GBM	IUPHAR	TNRC6A	SMG1	0.810845446	2.11E-41
GBM	Kinase	TNRC6A	SMG1	0.810845446	2.11E-41
THYM	Cell metabolism gene	TNRC6A	SMG1	0.801403786	1.48E-28
THYM	Cell metabolism gene	TNRC6A	CREBBP	0.81732804	1.64E-30
THYM	CGC	TNRC6A	TRIM33	0.803276955	8.91E-29
THYM	CGC	TNRC6A	MAP3K1	0.80653169	3.63E-29
THYM	CGC	TNRC6A	BIRC6	0.808120468	2.33E-29
THYM	CGC	TNRC6A	AKAP9	0.809114526	1.76E-29
THYM	CGC	TNRC6A	HOOK3	0.809502383	1.58E-29
THYM	CGC	TNRC6A	CREBBP	0.81732804	1.64E-30
THYM	CGC	TNRC6A	AFF4	0.819372588	8.88E-31
THYM	CGC	TNRC6A	CHD2	0.823961125	2.19E-31
THYM	CGC	TNRC6A	ZMYM2	0.827246408	7.86E-32
THYM	CGC	TNRC6A	DICER1	0.828668929	5.01E-32
THYM	CGC	TNRC6A	FBXO11	0.834988544	6.41E-33
THYM	CGC	TNRC6A	ATRX	0.854890453	5.36E-36
THYM	Epifactor	TNRC6A	SETD5	0.802121691	1.22E-28
THYM	Epifactor	TNRC6A	TRIM33	0.803276955	8.91E-29
THYM	Epifactor	TNRC6A	PHC3	0.810539677	1.18E-29
THYM	Epifactor	TNRC6A	ATF7IP	0.8121065	7.51E-30
THYM	Epifactor	TNRC6A	CREBBP	0.81732804	1.64E-30
THYM	Epifactor	TNRC6A	CHD2	0.823961125	2.19E-31
THYM	Epifactor	TNRC6A	ZMYM2	0.827246408	7.86E-32
THYM	Epifactor	TNRC6A	BAZ2B	0.844301464	2.63E-34
THYM	Epifactor	TNRC6A	ATRX	0.854890453	5.36E-36
THYM	Epifactor	TNRC6A	MYSM1	0.864473218	1.20E-37
THYM	IUPHAR	TNRC6A	TTBK2	0.800458733	1.91E-28
THYM	IUPHAR	TNRC6A	SMG1	0.801403786	1.48E-28
THYM	IUPHAR	TNRC6A	TAS2R5	0.801870471	1.31E-28
THYM	IUPHAR	TNRC6A	TRIM33	0.803276955	8.91E-29
THYM	IUPHAR	TNRC6A	MAP3K1	0.80653169	3.63E-29
THYM	IUPHAR	TNRC6A	BIRC6	0.808120468	2.33E-29
THYM	IUPHAR	TNRC6A	CREBBP	0.81732804	1.64E-30
THYM	IUPHAR	TNRC6A	TRPM7	0.822484698	3.46E-31
THYM	IUPHAR	TNRC6A	FBXO11	0.834988544	6.41E-33
THYM	IUPHAR	TNRC6A	BAZ2B	0.844301464	2.63E-34
THYM	Kinase	TNRC6A	TTBK2	0.800458733	1.91E-28
THYM	Kinase	TNRC6A	SMG1	0.801403786	1.48E-28
THYM	Kinase	TNRC6A	TRIM33	0.803276955	8.91E-29
THYM	Kinase	TNRC6A	MAP3K1	0.80653169	3.63E-29
THYM	Kinase	TNRC6A	TRPM7	0.822484698	3.46E-31
THYM	TF	TNRC6A	ZNF224	0.800045904	2.13E-28
THYM	TF	TNRC6A	ZNF621	0.800472553	1.90E-28
THYM	TF	TNRC6A	ZNF37A	0.800727418	1.78E-28
THYM	TF	TNRC6A	ZNF518A	0.801530166	1.43E-28
THYM	TF	TNRC6A	TMF1	0.802873406	9.94E-29
THYM	TF	TNRC6A	ZNF585B	0.814768436	3.47E-30
THYM	TF	TNRC6A	LCOR	0.814932145	3.31E-30
THYM	TF	TNRC6A	ZNF333	0.816156828	2.31E-30
THYM	TF	TNRC6A	ZNF236	0.831689018	1.90E-32
THYM	TF	TNRC6A	ZNF81	0.84134804	7.41E-34
THYM	TF	TNRC6A	ZNF587	0.843216298	3.86E-34
THYM	TF	TNRC6A	BAZ2B	0.844301464	2.63E-34
THYM	TF	TNRC6A	MYSM1	0.864473218	1.20E-37
THYM	TSG	TNRC6A	PHC3	0.810539677	1.18E-29
THYM	TSG	TNRC6A	CREBBP	0.81732804	1.64E-30
THYM	TSG	TNRC6A	DICER1	0.828668929	5.01E-32
UCS	Cell metabolism gene	TNRC6A	SMG1	0.801403786	1.48E-28
UCS	Cell metabolism gene	TNRC6A	CREBBP	0.81732804	1.64E-30
UCS	CGC	TNRC6A	TRIM33	0.803276955	8.91E-29
UCS	CGC	TNRC6A	MAP3K1	0.80653169	3.63E-29
UCS	CGC	TNRC6A	BIRC6	0.808120468	2.33E-29
UCS	CGC	TNRC6A	AKAP9	0.809114526	1.76E-29
UCS	CGC	TNRC6A	HOOK3	0.809502383	1.58E-29
UCS	CGC	TNRC6A	CREBBP	0.81732804	1.64E-30
UCS	CGC	TNRC6A	AFF4	0.819372588	8.88E-31
UCS	CGC	TNRC6A	CHD2	0.823961125	2.19E-31
UCS	CGC	TNRC6A	ZMYM2	0.827246408	7.86E-32
UCS	CGC	TNRC6A	DICER1	0.828668929	5.01E-32
UCS	CGC	TNRC6A	FBXO11	0.834988544	6.41E-33
UCS	CGC	TNRC6A	ATRX	0.854890453	5.36E-36
UCS	Epifactor	TNRC6A	SETD5	0.802121691	1.22E-28
UCS	Epifactor	TNRC6A	TRIM33	0.803276955	8.91E-29
UCS	Epifactor	TNRC6A	PHC3	0.810539677	1.18E-29
UCS	Epifactor	TNRC6A	ATF7IP	0.8121065	7.51E-30
UCS	Epifactor	TNRC6A	CREBBP	0.81732804	1.64E-30
UCS	Epifactor	TNRC6A	CHD2	0.823961125	2.19E-31
UCS	Epifactor	TNRC6A	ZMYM2	0.827246408	7.86E-32
UCS	Epifactor	TNRC6A	BAZ2B	0.844301464	2.63E-34
UCS	Epifactor	TNRC6A	ATRX	0.854890453	5.36E-36
UCS	Epifactor	TNRC6A	MYSM1	0.864473218	1.20E-37
UCS	IUPHAR	TNRC6A	TTBK2	0.800458733	1.91E-28
UCS	IUPHAR	TNRC6A	SMG1	0.801403786	1.48E-28
UCS	IUPHAR	TNRC6A	TAS2R5	0.801870471	1.31E-28
UCS	IUPHAR	TNRC6A	TRIM33	0.803276955	8.91E-29
UCS	IUPHAR	TNRC6A	MAP3K1	0.80653169	3.63E-29
UCS	IUPHAR	TNRC6A	BIRC6	0.808120468	2.33E-29
UCS	IUPHAR	TNRC6A	CREBBP	0.81732804	1.64E-30
UCS	IUPHAR	TNRC6A	TRPM7	0.822484698	3.46E-31
UCS	IUPHAR	TNRC6A	FBXO11	0.834988544	6.41E-33
UCS	IUPHAR	TNRC6A	BAZ2B	0.844301464	2.63E-34
UCS	Kinase	TNRC6A	TTBK2	0.800458733	1.91E-28
UCS	Kinase	TNRC6A	SMG1	0.801403786	1.48E-28
UCS	Kinase	TNRC6A	TRIM33	0.803276955	8.91E-29
UCS	Kinase	TNRC6A	MAP3K1	0.80653169	3.63E-29
UCS	Kinase	TNRC6A	TRPM7	0.822484698	3.46E-31
UCS	TF	TNRC6A	ZNF224	0.800045904	2.13E-28
UCS	TF	TNRC6A	ZNF621	0.800472553	1.90E-28
UCS	TF	TNRC6A	ZNF37A	0.800727418	1.78E-28
UCS	TF	TNRC6A	ZNF518A	0.801530166	1.43E-28
UCS	TF	TNRC6A	TMF1	0.802873406	9.94E-29
UCS	TF	TNRC6A	ZNF585B	0.814768436	3.47E-30
UCS	TF	TNRC6A	LCOR	0.814932145	3.31E-30
UCS	TF	TNRC6A	ZNF333	0.816156828	2.31E-30
UCS	TF	TNRC6A	ZNF236	0.831689018	1.90E-32
UCS	TF	TNRC6A	ZNF81	0.84134804	7.41E-34
UCS	TF	TNRC6A	ZNF587	0.843216298	3.86E-34
UCS	TF	TNRC6A	BAZ2B	0.844301464	2.63E-34
UCS	TF	TNRC6A	MYSM1	0.864473218	1.20E-37
UCS	TSG	TNRC6A	PHC3	0.810539677	1.18E-29
UCS	TSG	TNRC6A	CREBBP	0.81732804	1.64E-30
UCS	TSG	TNRC6A	DICER1	0.828668929	5.01E-32
UVM	Cell metabolism gene	TNRC6A	IDI1	0.800207244	5.35E-19
UVM	Cell metabolism gene	TNRC6A	MED17	0.801449394	4.30E-19
UVM	Cell metabolism gene	TNRC6A	PSMC6	0.801570885	4.21E-19
UVM	Cell metabolism gene	TNRC6A	GPAM	0.802602405	3.51E-19
UVM	Cell metabolism gene	TNRC6A	XPO1	0.803671757	2.90E-19
UVM	Cell metabolism gene	TNRC6A	ACADSB	0.804489906	2.51E-19
UVM	Cell metabolism gene	TNRC6A	MED4	0.805276796	2.18E-19
UVM	Cell metabolism gene	TNRC6A	ENOPH1	0.807905282	1.35E-19
UVM	Cell metabolism gene	TNRC6A	EDEM3	0.809293402	1.05E-19
UVM	Cell metabolism gene	TNRC6A	TPH1	0.809452398	1.02E-19
UVM	Cell metabolism gene	TNRC6A	TBL1XR1	0.810667778	8.13E-20
UVM	Cell metabolism gene	TNRC6A	NUDT12	0.810895563	7.80E-20
UVM	Cell metabolism gene	TNRC6A	PIK3R1	0.811059153	7.56E-20
UVM	Cell metabolism gene	TNRC6A	GRPEL2	0.811690572	6.72E-20
UVM	Cell metabolism gene	TNRC6A	MTMR6	0.813402719	4.88E-20
UVM	Cell metabolism gene	TNRC6A	NFYB	0.813584098	4.71E-20
UVM	Cell metabolism gene	TNRC6A	DCP2	0.815113961	3.52E-20
UVM	Cell metabolism gene	TNRC6A	DIS3	0.816740373	2.58E-20
UVM	Cell metabolism gene	TNRC6A	RORA	0.818294738	1.91E-20
UVM	Cell metabolism gene	TNRC6A	DCK	0.819559106	1.49E-20
UVM	Cell metabolism gene	TNRC6A	AMY2B	0.820193516	1.32E-20
UVM	Cell metabolism gene	TNRC6A	NUP107	0.820600339	1.22E-20
UVM	Cell metabolism gene	TNRC6A	PNPLA8	0.820819027	1.17E-20
UVM	Cell metabolism gene	TNRC6A	PPP1CB	0.821004942	1.12E-20
UVM	Cell metabolism gene	TNRC6A	TRMT11	0.821847924	9.51E-21
UVM	Cell metabolism gene	TNRC6A	GNAQ	0.823861408	6.36E-21
UVM	Cell metabolism gene	TNRC6A	MANEA	0.826539618	3.69E-21
UVM	Cell metabolism gene	TNRC6A	DBT	0.827672114	2.92E-21
UVM	Cell metabolism gene	TNRC6A	SLC19A2	0.828327347	2.55E-21
UVM	Cell metabolism gene	TNRC6A	SACM1L	0.828908361	2.26E-21
UVM	Cell metabolism gene	TNRC6A	PDE8A	0.83010515	1.76E-21
UVM	Cell metabolism gene	TNRC6A	PLA2G12A	0.83143557	1.33E-21
UVM	Cell metabolism gene	TNRC6A	ALG13	0.837419172	3.67E-22
UVM	Cell metabolism gene	TNRC6A	GNPDA2	0.846117229	5.12E-23
UVM	Cell metabolism gene	TNRC6A	NUPL2	0.846938332	4.23E-23
UVM	Cell metabolism gene	TNRC6A	NUPL1	0.847201498	3.97E-23
UVM	Cell metabolism gene	TNRC6A	CSGALNACT2	0.849098335	2.53E-23
UVM	Cell metabolism gene	TNRC6A	TRDMT1	0.853189648	9.42E-24
UVM	Cell metabolism gene	TNRC6A	MTR	0.853654954	8.40E-24
UVM	Cell metabolism gene	TNRC6A	PRKAA1	0.85386135	7.98E-24
UVM	Cell metabolism gene	TNRC6A	ALG10B	0.853908579	7.89E-24
UVM	Cell metabolism gene	TNRC6A	LPGAT1	0.854101081	7.52E-24
UVM	Cell metabolism gene	TNRC6A	PIKFYVE	0.855993087	4.69E-24
UVM	Cell metabolism gene	TNRC6A	NUP54	0.857926937	2.88E-24
UVM	Cell metabolism gene	TNRC6A	FBXL3	0.867469962	2.31E-25
UVM	Cell metabolism gene	TNRC6A	FAR1	0.870413039	1.02E-25
UVM	Cell metabolism gene	TNRC6A	RANBP2	0.870755995	9.26E-26
UVM	Cell metabolism gene	TNRC6A	SMG1	0.882136551	3.18E-27
UVM	Cell metabolism gene	TNRC6A	ETNK1	0.894776197	4.88E-29
UVM	Cell metabolism gene	TNRC6A	FBXW7	0.901496005	4.24E-30
UVM	Cell metabolism gene	TNRC6A	GXYLT1	0.907527858	4.06E-31
UVM	CGC	TNRC6A	AKAP9	0.801666811	4.14E-19
UVM	CGC	TNRC6A	XPO1	0.803671757	2.90E-19
UVM	CGC	TNRC6A	USP8	0.804169908	2.66E-19
UVM	CGC	TNRC6A	PALB2	0.806446497	1.76E-19
UVM	CGC	TNRC6A	JAK2	0.809804717	9.54E-20
UVM	CGC	TNRC6A	TBL1XR1	0.810667778	8.13E-20
UVM	CGC	TNRC6A	PIK3R1	0.811059153	7.56E-20
UVM	CGC	TNRC6A	ATF1	0.812180872	6.13E-20
UVM	CGC	TNRC6A	KIF5B	0.813426847	4.85E-20
UVM	CGC	TNRC6A	ZMYM2	0.814576838	3.90E-20
UVM	CGC	TNRC6A	RB1	0.818827398	1.72E-20
UVM	CGC	TNRC6A	BMPR1A	0.823051043	7.48E-21
UVM	CGC	TNRC6A	GNAQ	0.823861408	6.36E-21
UVM	CGC	TNRC6A	KTN1	0.824873929	5.18E-21
UVM	CGC	TNRC6A	ATR	0.831166016	1.41E-21
UVM	CGC	TNRC6A	APC	0.832526314	1.06E-21
UVM	CGC	TNRC6A	PWWP2A	0.833246976	9.08E-22
UVM	CGC	TNRC6A	ERCC4	0.833899565	7.89E-22
UVM	CGC	TNRC6A	FBXO11	0.834737529	6.59E-22
UVM	CGC	TNRC6A	KRAS	0.835128604	6.05E-22
UVM	CGC	TNRC6A	TRIM33	0.838415898	2.95E-22
UVM	CGC	TNRC6A	PSIP1	0.840075742	2.04E-22
UVM	CGC	TNRC6A	ARHGAP5	0.841111187	1.62E-22
UVM	CGC	TNRC6A	MAP3K1	0.848033032	3.27E-23
UVM	CGC	TNRC6A	SUZ12	0.849782215	2.15E-23
UVM	CGC	TNRC6A	DDX5	0.852086159	1.23E-23
UVM	CGC	TNRC6A	ATRX	0.85241368	1.14E-23
UVM	CGC	TNRC6A	CREB1	0.854597438	6.65E-24
UVM	CGC	TNRC6A	MDM4	0.859241003	2.06E-24
UVM	CGC	TNRC6A	BCLAF1	0.860075581	1.66E-24
UVM	CGC	TNRC6A	SMAD4	0.860834021	1.36E-24
UVM	CGC	TNRC6A	MLLT10	0.865386067	4.07E-25
UVM	CGC	TNRC6A	GOPC	0.868209673	1.88E-25
UVM	CGC	TNRC6A	ARID2	0.8697744	1.22E-25
UVM	CGC	TNRC6A	RANBP2	0.870755995	9.26E-26
UVM	CGC	TNRC6A	PMS1	0.875688665	2.24E-26
UVM	CGC	TNRC6A	TET2	0.887917165	5.01E-28
UVM	CGC	TNRC6A	PHF6	0.890363678	2.22E-28
UVM	CGC	TNRC6A	STAG2	0.891610803	1.46E-28
UVM	CGC	TNRC6A	ACVR2A	0.892063563	1.25E-28
UVM	CGC	TNRC6A	SF3B1	0.892957616	9.19E-29
UVM	CGC	TNRC6A	MALT1	0.893977387	6.46E-29
UVM	CGC	TNRC6A	ETNK1	0.894776197	4.88E-29
UVM	CGC	TNRC6A	RGPD3	0.900112395	7.12E-30
UVM	CGC	TNRC6A	FBXW7	0.901496005	4.24E-30
UVM	CGC	TNRC6A	DICER1	0.914037635	2.67E-32
UVM	Epifactor	TNRC6A	DDX50	0.800767335	4.85E-19
UVM	Epifactor	TNRC6A	NSL1	0.801390158	4.35E-19
UVM	Epifactor	TNRC6A	CTBP2	0.802394583	3.64E-19
UVM	Epifactor	TNRC6A	AEBP2	0.802709547	3.45E-19
UVM	Epifactor	TNRC6A	TDG	0.805167834	2.22E-19
UVM	Epifactor	TNRC6A	SUV420H1	0.806099092	1.88E-19
UVM	Epifactor	TNRC6A	EID1	0.806488747	1.75E-19
UVM	Epifactor	TNRC6A	PHF14	0.808905678	1.13E-19
UVM	Epifactor	TNRC6A	JAK2	0.809804717	9.54E-20
UVM	Epifactor	TNRC6A	EPC1	0.809894691	9.39E-20
UVM	Epifactor	TNRC6A	TBL1XR1	0.810667778	8.13E-20
UVM	Epifactor	TNRC6A	RSF1	0.811139395	7.45E-20
UVM	Epifactor	TNRC6A	PCGF6	0.811762724	6.63E-20
UVM	Epifactor	TNRC6A	NFYB	0.813584098	4.71E-20
UVM	Epifactor	TNRC6A	ANKRD32	0.813988299	4.36E-20
UVM	Epifactor	TNRC6A	TAF7	0.814040108	4.32E-20
UVM	Epifactor	TNRC6A	ZMYM2	0.814576838	3.90E-20
UVM	Epifactor	TNRC6A	SHPRH	0.816003907	2.97E-20
UVM	Epifactor	TNRC6A	SUDS3	0.816778717	2.56E-20
UVM	Epifactor	TNRC6A	MYSM1	0.818773438	1.74E-20
UVM	Epifactor	TNRC6A	RB1	0.818827398	1.72E-20
UVM	Epifactor	TNRC6A	CDK17	0.818936915	1.69E-20
UVM	Epifactor	TNRC6A	SIRT1	0.821099081	1.10E-20
UVM	Epifactor	TNRC6A	MPHOSPH8	0.821425662	1.03E-20
UVM	Epifactor	TNRC6A	SENP1	0.822173978	8.91E-21
UVM	Epifactor	TNRC6A	DNAJC2	0.822450833	8.43E-21
UVM	Epifactor	TNRC6A	MGEA5	0.823210678	7.24E-21
UVM	Epifactor	TNRC6A	BRCC3	0.825770436	4.32E-21
UVM	Epifactor	TNRC6A	TLK1	0.827889494	2.80E-21
UVM	Epifactor	TNRC6A	USP15	0.829504135	2.00E-21
UVM	Epifactor	TNRC6A	ATR	0.831166016	1.41E-21
UVM	Epifactor	TNRC6A	BRWD3	0.831352845	1.36E-21
UVM	Epifactor	TNRC6A	SMARCAD1	0.834525471	6.90E-22
UVM	Epifactor	TNRC6A	HMGB1	0.835162348	6.01E-22
UVM	Epifactor	TNRC6A	HCFC2	0.835731667	5.31E-22
UVM	Epifactor	TNRC6A	SMEK2	0.836993604	4.03E-22
UVM	Epifactor	TNRC6A	TRIM33	0.838415898	2.95E-22
UVM	Epifactor	TNRC6A	DNTTIP2	0.839914272	2.11E-22
UVM	Epifactor	TNRC6A	PSIP1	0.840075742	2.04E-22
UVM	Epifactor	TNRC6A	FAM175B	0.840670594	1.78E-22
UVM	Epifactor	TNRC6A	YEATS4	0.847203257	3.97E-23
UVM	Epifactor	TNRC6A	CIR1	0.849365708	2.38E-23
UVM	Epifactor	TNRC6A	SUZ12	0.849782215	2.15E-23
UVM	Epifactor	TNRC6A	MBIP	0.850206205	1.94E-23
UVM	Epifactor	TNRC6A	CUL5	0.850582416	1.78E-23
UVM	Epifactor	TNRC6A	CUL4B	0.851249299	1.51E-23
UVM	Epifactor	TNRC6A	TAF9B	0.851822576	1.32E-23
UVM	Epifactor	TNRC6A	ATRX	0.85241368	1.14E-23
UVM	Epifactor	TNRC6A	PRKAA1	0.85386135	7.98E-24
UVM	Epifactor	TNRC6A	PHC3	0.854470811	6.86E-24
UVM	Epifactor	TNRC6A	PCGF3	0.855005899	6.01E-24
UVM	Epifactor	TNRC6A	RLIM	0.856673416	3.96E-24
UVM	Epifactor	TNRC6A	BRWD1	0.860781627	1.38E-24
UVM	Epifactor	TNRC6A	ZMYND11	0.86367265	6.45E-25
UVM	Epifactor	TNRC6A	MLLT10	0.865386067	4.07E-25
UVM	Epifactor	TNRC6A	SMEK1	0.867822183	2.10E-25
UVM	Epifactor	TNRC6A	ARID2	0.8697744	1.22E-25
UVM	Epifactor	TNRC6A	ARID4B	0.873170629	4.65E-26
UVM	Epifactor	TNRC6A	EPC2	0.875694108	2.23E-26
UVM	Epifactor	TNRC6A	CUL2	0.880611621	5.10E-27
UVM	Epifactor	TNRC6A	CHD1	0.881545997	3.82E-27
UVM	Epifactor	TNRC6A	ATAD2B	0.8838118	1.88E-27
UVM	Epifactor	TNRC6A	RMI1	0.88436771	1.58E-27
UVM	Epifactor	TNRC6A	CHD9	0.884370649	1.58E-27
UVM	Epifactor	TNRC6A	INO80D	0.88494528	1.31E-27
UVM	Epifactor	TNRC6A	BAZ2B	0.885356676	1.15E-27
UVM	Epifactor	TNRC6A	TET2	0.887917165	5.01E-28
UVM	Epifactor	TNRC6A	PHIP	0.888520008	4.11E-28
UVM	Epifactor	TNRC6A	SF3B1	0.892957616	9.19E-29
UVM	Epifactor	TNRC6A	UHRF2	0.893524774	7.56E-29
UVM	Epifactor	TNRC6A	RCOR3	0.893596276	7.37E-29
UVM	Epifactor	TNRC6A	NIPBL	0.894406743	5.56E-29
UVM	Epifactor	TNRC6A	OGT	0.898469633	1.30E-29
UVM	Epifactor	TNRC6A	ARID4A	0.900174053	6.96E-30
UVM	Epifactor	TNRC6A	JMJD1C	0.901386301	4.42E-30
UVM	Epifactor	TNRC6A	MBTD1	0.907774072	3.67E-31
UVM	IUPHAR	TNRC6A	IDI1	0.800207244	5.35E-19
UVM	IUPHAR	TNRC6A	TTBK2	0.80030867	5.26E-19
UVM	IUPHAR	TNRC6A	MAP4K3	0.801942027	3.95E-19
UVM	IUPHAR	TNRC6A	XPO1	0.803671757	2.90E-19
UVM	IUPHAR	TNRC6A	NIPA1	0.804441857	2.53E-19
UVM	IUPHAR	TNRC6A	TPH1	0.809452398	1.02E-19
UVM	IUPHAR	TNRC6A	JAK2	0.809804717	9.54E-20
UVM	IUPHAR	TNRC6A	PIK3R1	0.811059153	7.56E-20
UVM	IUPHAR	TNRC6A	ATP11B	0.813162262	5.10E-20
UVM	IUPHAR	TNRC6A	TAS2R14	0.813448387	4.83E-20
UVM	IUPHAR	TNRC6A	MAP3K2	0.813537548	4.75E-20
UVM	IUPHAR	TNRC6A	PKN2	0.817372251	2.28E-20
UVM	IUPHAR	TNRC6A	NEK7	0.818010902	2.02E-20
UVM	IUPHAR	TNRC6A	RORA	0.818294738	1.91E-20
UVM	IUPHAR	TNRC6A	CDK17	0.818936915	1.69E-20
UVM	IUPHAR	TNRC6A	SIRT1	0.821099081	1.10E-20
UVM	IUPHAR	TNRC6A	SENP1	0.822173978	8.91E-21
UVM	IUPHAR	TNRC6A	BMPR1A	0.823051043	7.48E-21
UVM	IUPHAR	TNRC6A	SLC25A27	0.82309933	7.41E-21
UVM	IUPHAR	TNRC6A	ABCA5	0.823128778	7.36E-21
UVM	IUPHAR	TNRC6A	GNAQ	0.823861408	6.36E-21
UVM	IUPHAR	TNRC6A	CYP2R1	0.824499439	5.59E-21
UVM	IUPHAR	TNRC6A	CRBN	0.826228153	3.93E-21
UVM	IUPHAR	TNRC6A	TLK1	0.827889494	2.80E-21
UVM	IUPHAR	TNRC6A	SLC19A2	0.828327347	2.55E-21
UVM	IUPHAR	TNRC6A	PDE8A	0.83010515	1.76E-21
UVM	IUPHAR	TNRC6A	ATR	0.831166016	1.41E-21
UVM	IUPHAR	TNRC6A	YES1	0.831312778	1.37E-21
UVM	IUPHAR	TNRC6A	BRWD3	0.831352845	1.36E-21
UVM	IUPHAR	TNRC6A	PLA2G12A	0.83143557	1.33E-21
UVM	IUPHAR	TNRC6A	NAPEPLD	0.832724251	1.01E-21
UVM	IUPHAR	TNRC6A	IRAK4	0.833081562	9.40E-22
UVM	IUPHAR	TNRC6A	PRPF4B	0.834495226	6.94E-22
UVM	IUPHAR	TNRC6A	FBXO11	0.834737529	6.59E-22
UVM	IUPHAR	TNRC6A	KRAS	0.835128604	6.05E-22
UVM	IUPHAR	TNRC6A	TAS2R5	0.835874518	5.15E-22
UVM	IUPHAR	TNRC6A	SLK	0.837746948	3.42E-22
UVM	IUPHAR	TNRC6A	TRIM33	0.838415898	2.95E-22
UVM	IUPHAR	TNRC6A	SLC4A7	0.845731158	5.60E-23
UVM	IUPHAR	TNRC6A	STK38L	0.846095433	5.15E-23
UVM	IUPHAR	TNRC6A	MAP3K1	0.848033032	3.27E-23
UVM	IUPHAR	TNRC6A	MTR	0.853654954	8.40E-24
UVM	IUPHAR	TNRC6A	PRKAA1	0.85386135	7.98E-24
UVM	IUPHAR	TNRC6A	SLC25A36	0.855959484	4.73E-24
UVM	IUPHAR	TNRC6A	PIKFYVE	0.855993087	4.69E-24
UVM	IUPHAR	TNRC6A	TNKS2	0.856469004	4.16E-24
UVM	IUPHAR	TNRC6A	BRWD1	0.860781627	1.38E-24
UVM	IUPHAR	TNRC6A	ABCA10	0.861593313	1.12E-24
UVM	IUPHAR	TNRC6A	CSNK1G3	0.86315845	7.39E-25
UVM	IUPHAR	TNRC6A	ZMYND11	0.86367265	6.45E-25
UVM	IUPHAR	TNRC6A	NEK1	0.864957851	4.57E-25
UVM	IUPHAR	TNRC6A	RIOK3	0.865938847	3.51E-25
UVM	IUPHAR	TNRC6A	BIRC2	0.866525187	2.99E-25
UVM	IUPHAR	TNRC6A	NR2C1	0.872206434	6.14E-26
UVM	IUPHAR	TNRC6A	XIAP	0.872389796	5.82E-26
UVM	IUPHAR	TNRC6A	TRPM7	0.882124342	3.19E-27
UVM	IUPHAR	TNRC6A	SMG1	0.882136551	3.18E-27
UVM	IUPHAR	TNRC6A	ATAD2B	0.8838118	1.88E-27
UVM	IUPHAR	TNRC6A	BAZ2B	0.885356676	1.15E-27
UVM	IUPHAR	TNRC6A	PHIP	0.888520008	4.11E-28
UVM	IUPHAR	TNRC6A	NR3C1	0.890494816	2.13E-28
UVM	IUPHAR	TNRC6A	ACVR2A	0.892063563	1.25E-28
UVM	IUPHAR	TNRC6A	SENP6	0.893549166	7.49E-29
UVM	IUPHAR	TNRC6A	MALT1	0.893977387	6.46E-29
UVM	IUPHAR	TNRC6A	SENP7	0.899635538	8.49E-30
UVM	IUPHAR	TNRC6A	CLK1	0.900799137	5.51E-30
UVM	IUPHAR	TNRC6A	JMJD1C	0.901386301	4.42E-30
UVM	IUPHAR	TNRC6A	CLK4	0.92313933	4.05E-34
UVM	Kinase	TNRC6A	TTBK2	0.80030867	5.26E-19
UVM	Kinase	TNRC6A	MAP4K3	0.801942027	3.95E-19
UVM	Kinase	TNRC6A	JAK2	0.809804717	9.54E-20
UVM	Kinase	TNRC6A	MAP3K2	0.813537548	4.75E-20
UVM	Kinase	TNRC6A	PKN2	0.817372251	2.28E-20
UVM	Kinase	TNRC6A	NEK7	0.818010902	2.02E-20
UVM	Kinase	TNRC6A	CDK17	0.818936915	1.69E-20
UVM	Kinase	TNRC6A	BMPR1A	0.823051043	7.48E-21
UVM	Kinase	TNRC6A	TLK1	0.827889494	2.80E-21
UVM	Kinase	TNRC6A	ATR	0.831166016	1.41E-21
UVM	Kinase	TNRC6A	YES1	0.831312778	1.37E-21
UVM	Kinase	TNRC6A	IRAK4	0.833081562	9.40E-22
UVM	Kinase	TNRC6A	PRPF4B	0.834495226	6.94E-22
UVM	Kinase	TNRC6A	SLK	0.837746948	3.42E-22
UVM	Kinase	TNRC6A	TRIM33	0.838415898	2.95E-22
UVM	Kinase	TNRC6A	STK38L	0.846095433	5.15E-23
UVM	Kinase	TNRC6A	MAP3K1	0.848033032	3.27E-23
UVM	Kinase	TNRC6A	PRKAA1	0.85386135	7.98E-24
UVM	Kinase	TNRC6A	CSNK1G3	0.86315845	7.39E-25
UVM	Kinase	TNRC6A	NEK1	0.864957851	4.57E-25
UVM	Kinase	TNRC6A	RIOK3	0.865938847	3.51E-25
UVM	Kinase	TNRC6A	TRPM7	0.882124342	3.19E-27
UVM	Kinase	TNRC6A	SMG1	0.882136551	3.18E-27
UVM	Kinase	TNRC6A	ACVR2A	0.892063563	1.25E-28
UVM	Kinase	TNRC6A	CLK1	0.900799137	5.51E-30
UVM	Kinase	TNRC6A	PAN3	0.91206192	6.24E-32
UVM	Kinase	TNRC6A	CLK4	0.92313933	4.05E-34
UVM	TF	TNRC6A	ZNF506	0.801260149	4.45E-19
UVM	TF	TNRC6A	ZNF600	0.801348248	4.38E-19
UVM	TF	TNRC6A	ZNF502	0.801930884	3.95E-19
UVM	TF	TNRC6A	AEBP2	0.802709547	3.45E-19
UVM	TF	TNRC6A	ZNF709	0.80322878	3.14E-19
UVM	TF	TNRC6A	ZNF286A	0.803592566	2.95E-19
UVM	TF	TNRC6A	TIGD4	0.804598733	2.46E-19
UVM	TF	TNRC6A	ZBTB44	0.805295817	2.17E-19
UVM	TF	TNRC6A	ZNF879	0.806269723	1.82E-19
UVM	TF	TNRC6A	ZNF222	0.806402088	1.78E-19
UVM	TF	TNRC6A	ZNF587	0.807172025	1.55E-19
UVM	TF	TNRC6A	ZNF223	0.810456448	8.46E-20
UVM	TF	TNRC6A	ZNF420	0.810660808	8.15E-20
UVM	TF	TNRC6A	PCGF6	0.811762724	6.63E-20
UVM	TF	TNRC6A	ZNF627	0.812099487	6.23E-20
UVM	TF	TNRC6A	ATF1	0.812180872	6.13E-20
UVM	TF	TNRC6A	VEZF1	0.813008564	5.25E-20
UVM	TF	TNRC6A	ZNF326	0.813050667	5.21E-20
UVM	TF	TNRC6A	NFYB	0.813584098	4.71E-20
UVM	TF	TNRC6A	ZNF480	0.814505859	3.96E-20
UVM	TF	TNRC6A	ZNF564	0.814527654	3.94E-20
UVM	TF	TNRC6A	ZNF267	0.814905135	3.67E-20
UVM	TF	TNRC6A	ZNF236	0.815645671	3.18E-20
UVM	TF	TNRC6A	ZFP62	0.817736143	2.13E-20
UVM	TF	TNRC6A	RORA	0.818294738	1.91E-20
UVM	TF	TNRC6A	ZNF546	0.818411009	1.87E-20
UVM	TF	TNRC6A	MYSM1	0.818773438	1.74E-20
UVM	TF	TNRC6A	ZNF547	0.819042735	1.65E-20
UVM	TF	TNRC6A	ZNF654	0.819160812	1.61E-20
UVM	TF	TNRC6A	ZNF397	0.819476671	1.52E-20
UVM	TF	TNRC6A	ZNF230	0.819596824	1.48E-20
UVM	TF	TNRC6A	TTF1	0.819606074	1.48E-20
UVM	TF	TNRC6A	ZNF594	0.820084343	1.35E-20
UVM	TF	TNRC6A	ZNF81	0.820225389	1.31E-20
UVM	TF	TNRC6A	ZNF714	0.820288807	1.29E-20
UVM	TF	TNRC6A	ZNF514	0.82095766	1.13E-20
UVM	TF	TNRC6A	ZFP30	0.821539506	1.01E-20
UVM	TF	TNRC6A	FOXN2	0.822859002	7.77E-21
UVM	TF	TNRC6A	ZNF440	0.823592306	6.71E-21
UVM	TF	TNRC6A	TOPORS	0.825338032	4.72E-21
UVM	TF	TNRC6A	ZNF570	0.826825942	3.48E-21
UVM	TF	TNRC6A	MYNN	0.827232513	3.20E-21
UVM	TF	TNRC6A	ZNF235	0.828673772	2.38E-21
UVM	TF	TNRC6A	ZNF765	0.829068238	2.19E-21
UVM	TF	TNRC6A	ZNF484	0.829119557	2.17E-21
UVM	TF	TNRC6A	ZNF443	0.830024522	1.79E-21
UVM	TF	TNRC6A	ZNF799	0.830880334	1.50E-21
UVM	TF	TNRC6A	ZNF131	0.831432058	1.33E-21
UVM	TF	TNRC6A	ZBTB6	0.83325453	9.06E-22
UVM	TF	TNRC6A	ZNF791	0.834745353	6.58E-22
UVM	TF	TNRC6A	TIGD7	0.834763047	6.55E-22
UVM	TF	TNRC6A	PRDM10	0.834788548	6.52E-22
UVM	TF	TNRC6A	ZNF585B	0.835320108	5.81E-22
UVM	TF	TNRC6A	ZNF675	0.835335743	5.79E-22
UVM	TF	TNRC6A	ZNF569	0.836487326	4.51E-22
UVM	TF	TNRC6A	GABPA	0.836813238	4.20E-22
UVM	TF	TNRC6A	ZNF770	0.837733343	3.43E-22
UVM	TF	TNRC6A	ZNF780A	0.838405214	2.96E-22
UVM	TF	TNRC6A	ZBTB41	0.838586573	2.84E-22
UVM	TF	TNRC6A	ZNF383	0.839756022	2.19E-22
UVM	TF	TNRC6A	ZBTB34	0.841908517	1.35E-22
UVM	TF	TNRC6A	ZNF721	0.842350754	1.22E-22
UVM	TF	TNRC6A	ZNF354A	0.842537906	1.17E-22
UVM	TF	TNRC6A	MEF2A	0.842547555	1.17E-22
UVM	TF	TNRC6A	ZNF461	0.842736725	1.12E-22
UVM	TF	TNRC6A	ZSCAN29	0.843104731	1.03E-22
UVM	TF	TNRC6A	ZNF808	0.843406763	9.59E-23
UVM	TF	TNRC6A	SKIL	0.843675658	9.01E-23
UVM	TF	TNRC6A	ZNF143	0.843792962	8.77E-23
UVM	TF	TNRC6A	ZNF655	0.844060744	8.25E-23
UVM	TF	TNRC6A	ZNF345	0.844520065	7.42E-23
UVM	TF	TNRC6A	SP3	0.844609457	7.27E-23
UVM	TF	TNRC6A	ZNF169	0.84535164	6.12E-23
UVM	TF	TNRC6A	ZNF800	0.845924349	5.36E-23
UVM	TF	TNRC6A	ZNF227	0.846240447	4.98E-23
UVM	TF	TNRC6A	THAP5	0.846631	4.54E-23
UVM	TF	TNRC6A	ZNF519	0.846803695	4.36E-23
UVM	TF	TNRC6A	ZNF280C	0.848205917	3.13E-23
UVM	TF	TNRC6A	ZNF845	0.84896841	2.61E-23
UVM	TF	TNRC6A	RBAK	0.849081332	2.55E-23
UVM	TF	TNRC6A	ZNF430	0.849510257	2.30E-23
UVM	TF	TNRC6A	ZNF260	0.8496476	2.22E-23
UVM	TF	TNRC6A	ZNF43	0.850043442	2.02E-23
UVM	TF	TNRC6A	ZNF615	0.85136526	1.47E-23
UVM	TF	TNRC6A	ZNF624	0.851454485	1.44E-23
UVM	TF	TNRC6A	ZNF148	0.851705365	1.35E-23
UVM	TF	TNRC6A	ZNF28	0.85190422	1.29E-23
UVM	TF	TNRC6A	JRKL	0.852351236	1.16E-23
UVM	TF	TNRC6A	ZNF347	0.852365057	1.15E-23
UVM	TF	TNRC6A	ZNF558	0.853910905	7.88E-24
UVM	TF	TNRC6A	ZNF253	0.854465529	6.87E-24
UVM	TF	TNRC6A	IKZF5	0.854574895	6.69E-24
UVM	TF	TNRC6A	CREB1	0.854597438	6.65E-24
UVM	TF	TNRC6A	ZBTB49	0.854763865	6.38E-24
UVM	TF	TNRC6A	EEA1	0.854945551	6.10E-24
UVM	TF	TNRC6A	ZNF644	0.855073845	5.91E-24
UVM	TF	TNRC6A	ZNF189	0.857093966	3.56E-24
UVM	TF	TNRC6A	ZNF449	0.85823576	2.66E-24
UVM	TF	TNRC6A	ZNF585A	0.858319982	2.60E-24
UVM	TF	TNRC6A	ZNF701	0.859114973	2.12E-24
UVM	TF	TNRC6A	PURB	0.85928054	2.04E-24
UVM	TF	TNRC6A	ZNF470	0.859295169	2.03E-24
UVM	TF	TNRC6A	ZNF12	0.859823101	1.77E-24
UVM	TF	TNRC6A	ZNF417	0.859823357	1.77E-24
UVM	TF	TNRC6A	ZNF226	0.860357025	1.54E-24
UVM	TF	TNRC6A	ZFP28	0.860591573	1.45E-24
UVM	TF	TNRC6A	SMAD4	0.860834021	1.36E-24
UVM	TF	TNRC6A	ZNF268	0.861968016	1.01E-24
UVM	TF	TNRC6A	ZFX	0.862656486	8.44E-25
UVM	TF	TNRC6A	AHCTF1	0.862678286	8.39E-25
UVM	TF	TNRC6A	ZNF24	0.862747681	8.24E-25
UVM	TF	TNRC6A	ZNF566	0.863746571	6.32E-25
UVM	TF	TNRC6A	ZNF41	0.865318795	4.15E-25
UVM	TF	TNRC6A	ZNF254	0.865412314	4.04E-25
UVM	TF	TNRC6A	LIN54	0.865412487	4.04E-25
UVM	TF	TNRC6A	NFXL1	0.866473351	3.03E-25
UVM	TF	TNRC6A	ZNF507	0.86849044	1.74E-25
UVM	TF	TNRC6A	ZNF182	0.86957679	1.29E-25
UVM	TF	TNRC6A	ZNF266	0.869622904	1.27E-25
UVM	TF	TNRC6A	ARID2	0.8697744	1.22E-25
UVM	TF	TNRC6A	ZNF761	0.86999385	1.15E-25
UVM	TF	TNRC6A	ZNF44	0.870751601	9.27E-26
UVM	TF	TNRC6A	NR2C1	0.872206434	6.14E-26
UVM	TF	TNRC6A	ZNF140	0.8737778	3.91E-26
UVM	TF	TNRC6A	SMAD5	0.874382716	3.28E-26
UVM	TF	TNRC6A	ZNF674	0.875359555	2.46E-26
UVM	TF	TNRC6A	ZNF527	0.875965281	2.06E-26
UVM	TF	TNRC6A	ZNF320	0.87608258	1.99E-26
UVM	TF	TNRC6A	ZBTB11	0.876612445	1.70E-26
UVM	TF	TNRC6A	ZNF37A	0.876659522	1.68E-26
UVM	TF	TNRC6A	ZNF141	0.877155166	1.45E-26
UVM	TF	TNRC6A	ZNF708	0.877939863	1.15E-26
UVM	TF	TNRC6A	ZNF441	0.878862147	8.69E-27
UVM	TF	TNRC6A	ZBTB1	0.879493406	7.17E-27
UVM	TF	TNRC6A	ZNF432	0.879585584	6.97E-27
UVM	TF	TNRC6A	ZNF83	0.879699029	6.74E-27
UVM	TF	TNRC6A	ZNF75D	0.879917477	6.30E-27
UVM	TF	TNRC6A	ZNF354B	0.880153936	5.86E-27
UVM	TF	TNRC6A	ZNF23	0.881080537	4.41E-27
UVM	TF	TNRC6A	TMF1	0.881551786	3.81E-27
UVM	TF	TNRC6A	ZNF91	0.881975683	3.34E-27
UVM	TF	TNRC6A	ZNF14	0.882024538	3.29E-27
UVM	TF	TNRC6A	ZNF195	0.884327837	1.60E-27
UVM	TF	TNRC6A	THAP6	0.884466474	1.53E-27
UVM	TF	TNRC6A	ZBED5	0.884503107	1.51E-27
UVM	TF	TNRC6A	ZNF700	0.884958889	1.31E-27
UVM	TF	TNRC6A	ZNF136	0.88506139	1.26E-27
UVM	TF	TNRC6A	BAZ2B	0.885356676	1.15E-27
UVM	TF	TNRC6A	ELF2	0.885386806	1.14E-27
UVM	TF	TNRC6A	ZNF181	0.88586966	9.76E-28
UVM	TF	TNRC6A	ZNF26	0.885995553	9.37E-28
UVM	TF	TNRC6A	ZNF33A	0.886494986	7.97E-28
UVM	TF	TNRC6A	ZNF611	0.886610955	7.68E-28
UVM	TF	TNRC6A	ZNF234	0.887145051	6.45E-28
UVM	TF	TNRC6A	TET2	0.887917165	5.01E-28
UVM	TF	TNRC6A	ZNF180	0.88800929	4.86E-28
UVM	TF	TNRC6A	GPBP1	0.889272385	3.20E-28
UVM	TF	TNRC6A	ZNF280D	0.889773364	2.71E-28
UVM	TF	TNRC6A	NR3C1	0.890494816	2.13E-28
UVM	TF	TNRC6A	ZNF658	0.890495583	2.13E-28
UVM	TF	TNRC6A	ZNF292	0.890558119	2.08E-28
UVM	TF	TNRC6A	ZMAT1	0.892067839	1.25E-28
UVM	TF	TNRC6A	ZNF25	0.896548279	2.61E-29
UVM	TF	TNRC6A	ZNF567	0.89672971	2.44E-29
UVM	TF	TNRC6A	ZFP14	0.89684784	2.34E-29
UVM	TF	TNRC6A	ZNF224	0.897405268	1.92E-29
UVM	TF	TNRC6A	CREBZF	0.898059069	1.51E-29
UVM	TF	TNRC6A	ZNF302	0.901028893	5.06E-30
UVM	TF	TNRC6A	ZNF510	0.902005047	3.50E-30
UVM	TF	TNRC6A	THAP9	0.904908509	1.15E-30
UVM	TF	TNRC6A	ZNF431	0.907438209	4.21E-31
UVM	TF	TNRC6A	ZNF160	0.907709399	3.77E-31
UVM	TF	TNRC6A	ZNF529	0.908462757	2.78E-31
UVM	TF	TNRC6A	ZNF493	0.908756872	2.47E-31
UVM	TF	TNRC6A	ZNF84	0.909429764	1.87E-31
UVM	TF	TNRC6A	ZNF782	0.913777169	2.99E-32
UVM	TF	TNRC6A	ZNF518A	0.916065321	1.09E-32
UVM	TF	TNRC6A	ZNF780B	0.916392176	9.46E-33
UVM	TF	TNRC6A	ZNF606	0.918686358	3.34E-33
UVM	TF	TNRC6A	ZNF10	0.920593566	1.37E-33
UVM	TF	TNRC6A	DMTF1	0.933103269	2.18E-36
UVM	TF	TNRC6A	ZNF248	0.935170288	6.67E-37
UVM	TSG	TNRC6A	WDR11	0.804081413	2.70E-19
UVM	TSG	TNRC6A	NEDD4	0.806312548	1.81E-19
UVM	TSG	TNRC6A	PALB2	0.806446497	1.76E-19
UVM	TSG	TNRC6A	RASSF8	0.808255768	1.27E-19
UVM	TSG	TNRC6A	LIN9	0.812898912	5.36E-20
UVM	TSG	TNRC6A	FAM188A	0.81455974	3.92E-20
UVM	TSG	TNRC6A	SHPRH	0.816003907	2.97E-20
UVM	TSG	TNRC6A	MCM9	0.816416311	2.75E-20
UVM	TSG	TNRC6A	RB1	0.818827398	1.72E-20
UVM	TSG	TNRC6A	TTF1	0.819606074	1.48E-20
UVM	TSG	TNRC6A	USP33	0.820844959	1.16E-20
UVM	TSG	TNRC6A	SIRT1	0.821099081	1.10E-20
UVM	TSG	TNRC6A	BMPR1A	0.823051043	7.48E-21
UVM	TSG	TNRC6A	TOPORS	0.825338032	4.72E-21
UVM	TSG	TNRC6A	COPS2	0.828113974	2.67E-21
UVM	TSG	TNRC6A	SMCHD1	0.828885982	2.28E-21
UVM	TSG	TNRC6A	INTS6	0.83098399	1.47E-21
UVM	TSG	TNRC6A	ATR	0.831166016	1.41E-21
UVM	TSG	TNRC6A	APC	0.832526314	1.06E-21
UVM	TSG	TNRC6A	NAPEPLD	0.832724251	1.01E-21
UVM	TSG	TNRC6A	MLH3	0.842544679	1.17E-22
UVM	TSG	TNRC6A	SKIL	0.843675658	9.01E-23
UVM	TSG	TNRC6A	PPM1A	0.848702075	2.79E-23
UVM	TSG	TNRC6A	SUZ12	0.849782215	2.15E-23
UVM	TSG	TNRC6A	CUL5	0.850582416	1.78E-23
UVM	TSG	TNRC6A	CCAR1	0.85226499	1.18E-23
UVM	TSG	TNRC6A	VEZT	0.853856043	7.99E-24
UVM	TSG	TNRC6A	PRKAA1	0.85386135	7.98E-24
UVM	TSG	TNRC6A	PHC3	0.854470811	6.86E-24
UVM	TSG	TNRC6A	SMAD4	0.860834021	1.36E-24
UVM	TSG	TNRC6A	GORAB	0.862680345	8.39E-25
UVM	TSG	TNRC6A	ZMYND11	0.86367265	6.45E-25
UVM	TSG	TNRC6A	APAF1	0.868842172	1.58E-25
UVM	TSG	TNRC6A	ARID2	0.8697744	1.22E-25
UVM	TSG	TNRC6A	DCLRE1A	0.876540263	1.74E-26
UVM	TSG	TNRC6A	KRIT1	0.879193159	7.86E-27
UVM	TSG	TNRC6A	CUL2	0.880611621	5.10E-27
UVM	TSG	TNRC6A	CHD1	0.881545997	3.82E-27
UVM	TSG	TNRC6A	TET2	0.887917165	5.01E-28
UVM	TSG	TNRC6A	PHF6	0.890363678	2.22E-28
UVM	TSG	TNRC6A	ZNF292	0.890558119	2.08E-28
UVM	TSG	TNRC6A	TANK	0.89187271	1.33E-28
UVM	TSG	TNRC6A	UHRF2	0.893524774	7.56E-29
UVM	TSG	TNRC6A	PNN	0.895928763	3.25E-29
UVM	TSG	TNRC6A	FBXW7	0.901496005	4.24E-30
UVM	TSG	TNRC6A	DICER1	0.914037635	2.67E-32
UVM	TSG	TNRC6A	DMTF1	0.933103269	2.18E-36

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
CHOL	TNRC6A	PABPC1	-4.56272528815353	0.00390625
HNSC	TNRC6A	RQCD1	1.97297540658491	0.00585215220849023
KIRC	TNRC6A	DCP2	1.26475649682567	0.0124189994647713
PRAD	TNRC6A	DICER1	1.54768558737379	0.0130781232419534
BLCA	TNRC6A	PABPC1	1.31485302792746	0.0180816650390625
LIHC	TNRC6A	PABPC1	-1.72076961362188	2.98009622125841e-06
THCA	TNRC6A	DDX6	-4.18593714762416	8.3083675979354e-06
PRAD	TNRC6A	PABPC1	-2.10200318363476	8.55379952759014e-07

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with TNRC6A

AGO4, AGO2, WNK1, UBC, PABPC1, UBR5, CUL3, AGO1, AGO3, SAV1, TRIM65, CEP250, TRIP13, CNOT1, CNOT3, CNOT6L, CNOT7, CNOT10, PAN2, CNOT2, CNOT6, CNOT8, PAN3, BTRC, SSX2IP, CEP152, CNTROB, CEP135, CNTRL, NINL, ODF2, RPGRIP1L, CENPJ, ITGB4, CLTB, CLTC, PICALM, GTSE1, FANCM, KIAA2013, RQCD1, Ubr5, EYA2, SMARCB1, BRCA1, ESR2, EZH2, SUZ12, SFPQ, TRIM24, MED12, AHNAK2, PSPC1, PCF11, MED1, KMT2B, EIF2AK4, NCOA6, CPSF7, MED14, CLP1, MED17, MED13, TJP2, CDK5RAP3, CNOT11, ANAPC4, SRSF6, SEC63, TAP1, MED23, MED4, MED6, SCD, TP53BP1, CCAR2, ANAPC1, ARID1A, TNKS1BP1, GATAD2A, AFF4, CDC23, MDC1, ANAPC7, ANAPC5, CDC16, CDC27, NAT10, NES, SMARCD1, WDR5, KMT2C, ASH2L, RBBP5, ZNF24, MED27, HIST3H3, TOMM20, ZC3H7A, IKBKG, TNIP2, NR2C2, PATL1, DDX6, ZBTB10, BICD2, BICD1, NIN, ARIH2, MIB1, HCVgp1, HIST2H2BC, nsp12, nsp7, ESR1, ANKRD17, CELF1, CEP85, CPEB4, DAZL, FAM120C, FUBP3, KIAA0355, MEX3B, PRRC2A, PUM1, R3HDM2, ANKHD1-EIF4EBP3, DCP1B, DLG5, EIF4E2, EIF4ENIF1, GIGYF1, GIGYF2, HELZ, KIAA0430, PRRC2B, RC3H1, RC3H2, RNF219, SMG5, SMG7, TBK1, TBKBP1, TNRC6B, TNRC6C, AP2A1, AP2B1, AP2M1, CEP192, CYLD, DCP1A, DCP2, EDC3, EDC4, EDRF1, FAM175B, FAM184A, FAM193A, FBF1, GPBP1, GPBP1L1, ITSN2, KIZ, KLHL15, LZTS2, MIB2, MPHOSPH9, NME7, SCLT1, SEC23B, SPATA2, TCHP, TRIP11, USP54, UBAP2L, UNK, YTHDF1, YTHDF2, YTHDF3, ZFP36, MOV10, ALG13, KANK2, SYNM, TNPO1, BTG3, SEC16A, AP2A2, SEC24B, TXLNG, ZC3HAV1, MKRN2, RBMS1, CNOT4, OTUD4, TNPO2, CPVL, DZIP3, KIF14, KIF20A, PHIP, TRIM66, TRIM37, ACTR3, AKAP1, AMOT, ANAPC2, CLTA, EMD, GFAP, IMPDH2, KDM1A, KRT18, KRT19, KRT8, LATS1, MLLT4, NUP155, PRPH, PXN, RPS20, SASS6, SERBP1, SQSTM1, STIL, STX4, SYNE3, VASP, VIM, ZYX, FKBP9, AK4, QKI, DMRTB1, TXNL4A, RBFOX2, Ssbp1, N, CPEB1, GLI3, ISX, RB1CC1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
TNRC6A	chr16	24788422	AGCAGCCACAGCC	A	Deletion	Benign	not_provided	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
TNRC6A	chr16	24788549	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
TNRC6A	chr16	24788645	T	A	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
TNRC6A	chr16	24801145	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
TNRC6A	chr16	24801638	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
TNRC6A	chr16	24802366	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
TNRC6A	chr16	24802572	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
TNRC6A	chr16	24802972	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
TNRC6A	chr16	24817614	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
TNRC6A	chr16	24818114	C	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
TNRC6A	chr16	24831640	T	C	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
TNRC6A	chr16	24834950	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
TNRC6A	BLCA	chr16	24826541	24826541	A	C	Silent		7
TNRC6A	COAD	chr16	24788423	24788434	GCAGCCACAGCC	-	In_Frame_Del	p.111_115del	7
TNRC6A	KIRC	chr16	24802365	24802366	-	G	Frame_Shift_Ins	p.R801fs	5
TNRC6A	CESC	chr16	24788506	24788506	G	A	Missense_Mutation	p.R139Q	5
TNRC6A	LUAD	chr16	24817548	24817548	A	G	Missense_Mutation	p.R1425G	5
TNRC6A	BLCA	chr16	24807240	24807240	A	-	Frame_Shift_Del	p.K1182fs	4
TNRC6A	SKCM	chr16	24828142	24828142	C	T	Missense_Mutation	p.R1613C	4
TNRC6A	HNSC	chr16	24826581	24826581	C	T	Missense_Mutation	p.R1596C	4
TNRC6A	KIRP	chr16	24826534	24826534	G	A	Missense_Mutation	p.S1580N	4
TNRC6A	PCPG	chr16	24817584	24817584	C	T	Missense_Mutation	p.R1437W	4
TNRC6A	BRCA	chr16	24807329	24807332	ATTT	-	Frame_Shift_Del	p.I192fs	4
TNRC6A	LGG	chr16	24817937	24817937	C	T	Missense_Mutation	p.R1458C	4
TNRC6A	SKCM	chr16	24801035	24801035	C	T	Missense_Mutation	p.P358S	4
TNRC6A	UCEC	chr16	24826565	24826565	A	G	Missense_Mutation	p.I1590M	3
TNRC6A	LUAD	chr16	24834793	24834793	A	T	Missense_Mutation	p.S1852C	3
TNRC6A	BLCA	chr16	24807240	24807240	A	-	Frame_Shift_Del	p.K1181fs	3
TNRC6A	SARC	chr16	24815560	24815560	C	T	Nonsense_Mutation	p.R1253*	3
TNRC6A	LIHC	chr16	24762087	24762087	A	-	Frame_Shift_Del	p.K35fs	3
TNRC6A	BRCA	chr16	24801088	24801088	C	T	Silent	p.N375	3
TNRC6A	PCPG	chr16	24817584	24817584	C	T	Missense_Mutation		3
TNRC6A	STAD	chr16	24802366	24802366	G	-	Frame_Shift_Del	p.Q801fs	3
TNRC6A	UCEC	chr16	24802677	24802677	A	G	Missense_Mutation	p.N905S	3
TNRC6A	BLCA	chr16	24788506	24788506	G	T	Missense_Mutation		3
TNRC6A	BRCA	chr16	24801817	24801817	C	A	Missense_Mutation	p.N618K	3
TNRC6A	UCEC	chr16	24831626	24831626	T	A	Missense_Mutation	p.N1749K	3
TNRC6A	LUAD	chr16	24801933	24801933	A	T	Missense_Mutation	p.N657I	3
TNRC6A	LIHC	chr16	24816089	24816089	C	-	Frame_Shift_Del	p.P1302fs	3
TNRC6A	HNSC	chr16	24802394	24802394	A	G	Missense_Mutation	p.T811A	3
TNRC6A	LIHC	chr16	24834929	24834929	T	G	Missense_Mutation	p.L1897R	3
TNRC6A	LUAD	chr16	24762097	24762097	A	C	Missense_Mutation	p.K35T	3
TNRC6A	LIHC	chr16	24818061	24818061	A	-	Frame_Shift_Del	p.Q1499fs	3
TNRC6A	ESCA	chr16	24818001	24818001	A	G	Missense_Mutation	p.H1479R	3
TNRC6A	LIHC	chr16	24826473	24826473	A	C	Missense_Mutation		3
TNRC6A	BRCA	chr16	24831678	24831678	C	T	Missense_Mutation	p.P1767S	3
TNRC6A	BLCA	chr16	24802570	24802570	C	T	Silent	p.A869A	3
TNRC6A	KIRP	chr16	24801321	24801321	C	G	Missense_Mutation	p.P453R	3
TNRC6A	BRCA	chr16	24833445	24833445	G	A	Missense_Mutation	p.V1784I	3
TNRC6A	HNSC	chr16	24826581	24826581	C	T	Missense_Mutation		3
TNRC6A	HNSC	chr16	24835045	24835045	G	A	Missense_Mutation	p.D1936N	3
TNRC6A	UCEC	chr16	24802899	24802899	C	T	Missense_Mutation	p.A979V	3
TNRC6A	LIHC	chr16	24831552	24831552	A	-	Frame_Shift_Del	p.K1725fs	3
TNRC6A	LIHC	chr16	24834929	24834929	T	G	Missense_Mutation		3
TNRC6A	COAD	chr16	24835087	24835087	C	A	Missense_Mutation	p.L1950I	3
TNRC6A	KIRP	chr16	24788620	24788620	C	G	Missense_Mutation	p.A177G	3
TNRC6A	SKCM	chr16	24802755	24802755	C	T	Missense_Mutation	p.S931F	3
TNRC6A	UCEC	chr16	24788584	24788584	C	A	Missense_Mutation	p.A165D	3
TNRC6A	CHOL	chr16	24788389	24788389	A	C	Missense_Mutation		3
TNRC6A	SKCM	chr16	24801572	24801572	C	T	Missense_Mutation	p.P537S	2
TNRC6A	KIRP	chr16	24802526	24802526	G	-	Frame_Shift_Del	p.D855fs	2
TNRC6A	STAD	chr16	24803029	24803029	G	T	Missense_Mutation	p.W1022C	2
TNRC6A	BLCA	chr16	24815594	24815594	A	G	Missense_Mutation	p.Q1264R	2
TNRC6A	CESC	chr16	24800641	24800641	G	A	Silent		2
TNRC6A	LIHC	chr16	24816121	24816121	C	A	Silent	p.A1311A	2
TNRC6A	UCEC	chr16	24808845	24808845	C	T	Missense_Mutation	p.A1199V	2
TNRC6A	HNSC	chr16	24800997	24800997	G	C	Missense_Mutation	p.W345S	2
TNRC6A	STAD	chr16	24834270	24834270	G	A	Missense_Mutation	p.G1817R	2
TNRC6A	BLCA	chr16	24803020	24803020	G	A	Silent	p.V1019V	2
TNRC6A	STAD	chr16	24815625	24815625	T	C	Silent	p.N1274N	2
TNRC6A	LGG	chr16	24817937	24817937	C	T	Missense_Mutation		2
TNRC6A	UCEC	chr16	24801346	24801346	C	A	Silent	p.T461	2
TNRC6A	CHOL	chr16	24826538	24826538	T	G	Silent		2
TNRC6A	ESCA	chr16	24818001	24818001	A	G	Missense_Mutation		2
TNRC6A	STAD	chr16	24816169	24816169	A	T	Missense_Mutation	p.R1327S	2
TNRC6A	BLCA	chr16	24815516	24815516	G	A	Missense_Mutation	p.R1238Q	2
TNRC6A	CESC	chr16	24805874	24805874	C	G	Missense_Mutation		2
TNRC6A	LIHC	chr16	24788429	24788429	A	G	Silent	p.P113P	2
TNRC6A	UCEC	chr16	24815565	24815565	G	A	Silent	p.G194S	2
TNRC6A	LUAD	chr16	24801038	24801038	A	T	Missense_Mutation	p.S359C	2
TNRC6A	LGG	chr16	24788441	24788441	G	A	Silent	p.P117P	2
TNRC6A	BLCA	chr16	24816470	24816470	C	T	Nonsense_Mutation	p.Q1374*	2
TNRC6A	STAD	chr16	24820702	24820702	T	A	Missense_Mutation	p.D1524E	2
TNRC6A	LIHC	chr16	24816374	24816374	G	T	Missense_Mutation		2
TNRC6A	UCEC	chr16	24801529	24801529	G	A	Nonsense_Mutation	p.W522*	2
TNRC6A	CHOL	chr16	24826538	24826538	T	G	Silent	p.T1581T	2
TNRC6A	ESCA	chr16	24788375	24788375	A	G	Silent		2
TNRC6A	SKCM	chr16	24826599	24826599	G	A	Missense_Mutation	p.G1602S	2
TNRC6A	STAD	chr16	24788506	24788506	G	T	Missense_Mutation	p.R139L	2
TNRC6A	BLCA	chr16	24817006	24817006	G	A	Silent	p.L1401L	2
TNRC6A	LIHC	chr16	24831569	24831569	G	A	Silent	p.P1730P	2
TNRC6A	UCEC	chr16	24816352	24816352	G	A	Missense_Mutation	p.M1334I	2
TNRC6A	UCEC	chr16	24741605	24741605	G	T	Nonsense_Mutation	p.E13*	2
TNRC6A	LUAD	chr16	24804935	24804935	C	G	Missense_Mutation	p.S1106C	2
TNRC6A	UCS	chr16	24834300	24834300	G	T	Nonsense_Mutation	p.E1827*	2
TNRC6A	STAD	chr16	24817959	24817959	T	C	Missense_Mutation	p.L1465S	2
TNRC6A	BLCA	chr16	24802034	24802034	C	T	Nonsense_Mutation	p.Q691*	2
TNRC6A	STAD	chr16	24828182	24828182	C	A	Missense_Mutation	p.P1626H	2
TNRC6A	THYM	chr16	24788444	24788444	G	A	Silent	p.Q118Q	2
TNRC6A	UCEC	chr16	24802006	24802006	C	T	Silent	p.R681	2
TNRC6A	SKCM	chr16	24826600	24826600	G	A	Missense_Mutation	p.G1602D	2
TNRC6A	HNSC	chr16	24801674	24801674	G	A	Missense_Mutation	p.G571S	2
TNRC6A	BLCA	chr16	24802299	24802299	C	T	Missense_Mutation	p.S779F	2
TNRC6A	LUAD	chr16	24803129	24803129	A	T	Missense_Mutation	p.S1056C	2
TNRC6A	UCEC	chr16	24818078	24818078	A	G	Missense_Mutation	p.I1505V	2
TNRC6A	LIHC	chr16	24800799	24800799	A	-	Frame_Shift_Del	p.E279fs	2
TNRC6A	UCEC	chr16	24762107	24762107	G	T	Missense_Mutation	p.K38N	2
TNRC6A	LUAD	chr16	24826516	24826516	A	T	Missense_Mutation	p.Y1574F	2
TNRC6A	HNSC	chr16	24800705	24800705	G	C	Missense_Mutation	p.E248Q	2
TNRC6A	STAD	chr16	24802783	24802783	A	T	Silent	p.P940P	2
TNRC6A	BLCA	chr16	24802570	24802570	C	T	Silent		2
TNRC6A	BLCA	chr16	24801938	24801938	C	G	Missense_Mutation	p.Q659E	2
TNRC6A	STAD	chr16	24803058	24803058	G	A	Missense_Mutation	p.R1032H	2
TNRC6A	UCEC	chr16	24802265	24802265	G	T	Missense_Mutation	p.D768Y	2
TNRC6A	COAD	chr16	24788434	24788434	C	A	Missense_Mutation	p.P115Q	2
TNRC6A	SKCM	chr16	24817563	24817563	A	G	Missense_Mutation	p.R1430G	2
TNRC6A	HNSC	chr16	24834933	24834933	T	A	Missense_Mutation	p.N1898K	2
TNRC6A	UCEC	chr16	24826566	24826566	G	T	Nonsense_Mutation	p.G1591*	2
TNRC6A	UCEC	chr16	24788401	24788401	C	T	Missense_Mutation	p.P104L	2
TNRC6A	ESCA	chr16	24815534	24815534	A	T	Missense_Mutation	p.H1244L	2
TNRC6A	HNSC	chr16	24800634	24800634	A	T	Missense_Mutation	p.N224I	2
TNRC6A	STAD	chr16	24802619	24802619	G	A	Missense_Mutation	p.G886S	2
TNRC6A	BLCA	chr16	24802435	24802435	G	C	Missense_Mutation	p.E824D	2
TNRC6A	STAD	chr16	24802947	24802947	T	C	Missense_Mutation	p.I995T	2
TNRC6A	TGCT	chr16	24826529	24826529	C	T	Silent		2
TNRC6A	UCEC	chr16	24802307	24802307	G	A	Missense_Mutation	p.G782R	2
TNRC6A	SKCM	chr16	24817561	24817561	A	G	Missense_Mutation	p.Q1429R	2
TNRC6A	LGG	chr16	24788378	24788378	G	T	Missense_Mutation	p.Q96H	2
TNRC6A	STAD	chr16	24803039	24803039	G	A	Missense_Mutation	p.V1026I	2
TNRC6A	UCEC	chr16	24829957	24829957	C	A	Silent	p.L563M	2
TNRC6A	UCEC	chr16	24788441	24788441	G	A	Silent	p.P117	2
TNRC6A	CESC	chr16	24831599	24831599	G	T	Missense_Mutation	p.Q1740H	2
TNRC6A	STAD	chr16	24802952	24802952	C	T	Missense_Mutation	p.R997C	2
TNRC6A	BLCA	chr16	24826603	24826603	C	G	Missense_Mutation	p.S1603C	2
TNRC6A	BLCA	chr16	24801369	24801369	C	T	Missense_Mutation		2
TNRC6A	UCEC	chr16	24802415	24802415	C	T	Nonsense_Mutation	p.Q818*	2
TNRC6A	SKCM	chr16	24831623	24831623	T	A	Missense_Mutation	p.D1748E	2
TNRC6A	SKCM	chr16	24831582	24831582	C	A	Missense_Mutation	p.P1735T	2
TNRC6A	STAD	chr16	24802647	24802647	C	A	Missense_Mutation	p.S895Y	2
TNRC6A	UCEC	chr16	24829988	24829988	G	A	Missense_Mutation	p.V1683I	2
TNRC6A	LIHC	chr16	24835083	24835083	T	-	Frame_Shift_Del	p.A1948fs	2
TNRC6A	UCEC	chr16	24788596	24788596	T	C	Missense_Mutation	p.L169S	2
TNRC6A	LGG	chr16	24802981	24802981	A	C	Silent		2
TNRC6A	STAD	chr16	24834864	24834864	C	T	Silent	p.L1875L	2
TNRC6A	BLCA	chr16	24808841	24808841	G	C	Missense_Mutation	p.E1198Q	2
TNRC6A	STAD	chr16	24805922	24805922	G	T	Missense_Mutation	p.R1137L	2
TNRC6A	UCEC	chr16	24802458	24802458	C	T	Missense_Mutation	p.S832L	2
TNRC6A	SKCM	chr16	24831624	24831624	A	C	Missense_Mutation	p.N1749H	2
TNRC6A	SKCM	chr16	24816999	24816999	C	T	Missense_Mutation	p.A1399V	2
TNRC6A	STAD	chr16	24817979	24817979	C	T	Missense_Mutation	p.P1472S	2
TNRC6A	BLCA	chr16	24800967	24800967	C	T	Missense_Mutation	p.S335F	2
TNRC6A	UCEC	chr16	24831637	24831637	G	A	Missense_Mutation	p.R1753H	2
TNRC6A	UCEC	chr16	24788637	24788637	C	T	Missense_Mutation	p.P183S	2
TNRC6A	ESCA	chr16	24788428	24788428	C	A	Missense_Mutation	p.P113Q	2
TNRC6A	STAD	chr16	24820702	24820702	T	A	Missense_Mutation		2
TNRC6A	LGG	chr16	24802982	24802982	G	C	Missense_Mutation		2
TNRC6A	STAD	chr16	24788440	24788440	C	A	Missense_Mutation	p.P117Q	2
TNRC6A	CESC	chr16	24831599	24831599	G	T	Missense_Mutation		2
TNRC6A	LUAD	chr16	24801619	24801619	G	T	Missense_Mutation	p.Q552H	2
TNRC6A	UCEC	chr16	24802773	24802773	C	T	Missense_Mutation	p.S937L	2
TNRC6A	SKCM	chr16	24801472	24801472	C	T	Silent	p.S503S	2
TNRC6A	HNSC	chr16	24829935	24829935	C	T	Missense_Mutation	p.T1665I	2
TNRC6A	LGG	chr16	24802267	24802267	T	C	Silent	p.D768D	2
TNRC6A	STAD	chr16	24806029	24806029	A	G	Missense_Mutation	p.M1173V	2
TNRC6A	LIHC	chr16	24802369	24802369	G	A	Silent	p.G802G	2
TNRC6A	UCEC	chr16	24834197	24834197	C	T	Silent	p.R683*	2
TNRC6A	BLCA	chr16	24801369	24801369	C	T	Missense_Mutation	p.S469L	2
TNRC6A	UCEC	chr16	24800899	24800899	A	G	Silent	p.P312	2
TNRC6A	ESCA	chr16	24802699	24802699	A	T	Missense_Mutation	p.E912D	2
TNRC6A	STAD	chr16	24815625	24815625	T	C	Silent		2
TNRC6A	LGG	chr16	24802267	24802267	T	C	Silent		2
TNRC6A	SKCM	chr16	24802347	24802347	C	T	Missense_Mutation	p.S795F	2
TNRC6A	KIRP	chr16	24802526	24802526	G	-	Frame_Shift_Del	p.S854fs	2
TNRC6A	LIHC	chr16	24816121	24816121	C	A	Silent		2
TNRC6A	BLCA	chr16	24818089	24818089	C	T	Silent	p.F1508F	2
TNRC6A	CESC	chr16	24835021	24835021	C	A	Missense_Mutation		2
TNRC6A	UCEC	chr16	24802902	24802904	AAG	-	In_Frame_Del	p.E983in_frame_del	2
TNRC6A	HNSC	chr16	24816384	24816384	G	A	Missense_Mutation	p.R1345Q	2
TNRC6A	LGG	chr16	24802981	24802981	A	C	Silent	p.S1006S	2
TNRC6A	STAD	chr16	24801521	24801521	A	G	Missense_Mutation	p.T520A	2
TNRC6A	BLCA	chr16	24815516	24815516	G	A	Missense_Mutation		2
TNRC6A	UCEC	chr16	24834277	24834277	C	T	Missense_Mutation	p.A1819V	2
TNRC6A	BLCA	chr16	24801938	24801938	C	G	Missense_Mutation		2
TNRC6A	UCEC	chr16	24801003	24801003	C	G	Missense_Mutation	p.T347S	2
TNRC6A	KIRC	chr16	24788568	24788568	G	A	Missense_Mutation	p.A160T	2
TNRC6A	STAD	chr16	24816407	24816407	C	G	Missense_Mutation	p.Q1353E	2
TNRC6A	LGG	chr16	24788378	24788378	G	T	Missense_Mutation		2
TNRC6A	STAD	chr16	24817552	24817552	C	T	Missense_Mutation	p.A1426V	2
TNRC6A	LIHC	chr16	24831569	24831569	G	A	Silent		2
TNRC6A	CESC	chr16	24826503	24826503	C	T	Missense_Mutation		2
TNRC6A	LIHC	chr16	24802560	24802560	G	-	Frame_Shift_Del	p.W866fs	2
TNRC6A	LUAD	chr16	24802953	24802953	G	T	Missense_Mutation	p.R997L	2
TNRC6A	UCEC	chr16	24805947	24805947	G	T	Nonsense_Mutation	p.G85*	2
TNRC6A	HNSC	chr16	24801451	24801451	A	T	Silent	p.P496P	2
TNRC6A	LGG	chr16	24802982	24802982	G	C	Missense_Mutation	p.A1007P	2
TNRC6A	LUAD	chr16	24834870	24834870	C	T	Silent	p.S1877S	2
TNRC6A	UCEC	chr16	24835005	24835005	G	A	Silent	p.A813T	2
TNRC6A	THYM	chr16	24816122	24816122	C	A	Missense_Mutation		2
TNRC6A	UCEC	chr16	24801151	24801151	T	C	Silent	p.S396	2
TNRC6A	ESCA	chr16	24815534	24815534	A	T	Missense_Mutation		2
TNRC6A	KIRC	chr16	24816069	24816069	C	T	Missense_Mutation	p.S1294F	2
TNRC6A	LGG	chr16	24788379	24788379	C	T	Nonsense_Mutation		2
TNRC6A	PAAD	chr16	24831545	24831545	G	A	Silent		1
TNRC6A	HNSC	chr16	24800705	24800705	G	C	Missense_Mutation		1
TNRC6A	SKCM	chr16	24804818	24804818	C	T	Missense_Mutation	p.P1067L	1
TNRC6A	UCEC	chr16	24835005	24835005	G	A	Silent	p.P1922P	1
TNRC6A	LUAD	chr16	24802584	24802584	G	T	Missense_Mutation	p.S874I	1
TNRC6A	COAD	chr16	24802313	24802313	G	T	Missense_Mutation	p.G784C	1
TNRC6A	LIHC	chr16	24802674	24802675	-	A	Frame_Shift_Ins	p.Q904fs	1
TNRC6A	UCEC	chr16	24802902	24802904	AAG	-	In_Frame_Del	p.E983del	1
TNRC6A	LUAD	chr16	24828156	24828156	A	G	Silent	p.P1617P	1
TNRC6A	UCS	chr16	24802366	24802366	G	-	Frame_Shift_Del		1
TNRC6A	LUAD	chr16	24801401	24801401	A	T	Missense_Mutation	p.T480S	1
TNRC6A	DLBC	chr16	24802245	24802245	T	G	Missense_Mutation	p.F761C	1
TNRC6A	READ	chr16	24801675	24801675	G	A	Missense_Mutation	p.G571D	1
TNRC6A	HNSC	chr16	24818089	24818089	C	T	Silent		1
TNRC6A	SKCM	chr16	24803121	24803121	A	G	Missense_Mutation	p.E1053G	1
TNRC6A	LGG	chr16	24800571	24800571	C	G	Nonsense_Mutation	p.S203*	1
TNRC6A	BLCA	chr16	24817006	24817006	G	A	Silent		1
TNRC6A	KIRC	chr16	24802866	24802866	C	A	Missense_Mutation	p.T968K	1
TNRC6A	STAD	chr16	24802194	24802194	G	A	Missense_Mutation	p.R744Q	1
TNRC6A	LIHC	chr16	24834848	24834848	C	A	Missense_Mutation		1
TNRC6A	THYM	chr16	24818020	24818021	TT	-	Frame_Shift_Del		1
TNRC6A	LIHC	chr16	24788537	24788537	A	-	Frame_Shift_Del	p.L149fs	1
TNRC6A	MESO	chr16	24788482	24788482	G	A	Missense_Mutation		1
TNRC6A	SARC	chr16	24817054	24817054	G	T	Splice_Site	p.Q1417_splice	1
TNRC6A	COAD	chr16	24802325	24802325	C	T	Missense_Mutation	p.P788S	1
TNRC6A	PAAD	chr16	24788479	24788479	C	A	Missense_Mutation	p.P130H	1
TNRC6A	HNSC	chr16	24801451	24801451	A	T	Silent		1
TNRC6A	SKCM	chr16	24834251	24834251	C	T	Silent	p.F1810F	1
TNRC6A	KIRP	chr16	24801321	24801321	C	G	Missense_Mutation		1
TNRC6A	LIHC	chr16	24820735	24820735	A	-	Frame_Shift_Del	p.L1535fs	1
TNRC6A	UCEC	chr16	24802656	24802656	G	-	Frame_Shift_Del	p.W898fs	1
TNRC6A	UCS	chr16	24834300	24834300	G	T	Nonsense_Mutation	p.E1827X	1
TNRC6A	LUAD	chr16	24808843	24808843	A	C	Missense_Mutation	p.E1198D	1
TNRC6A	DLBC	chr16	24802204	24802204	C	T	Silent	p.D747D	1
TNRC6A	READ	chr16	24801755	24801755	C	T	Nonsense_Mutation	p.R598X	1
TNRC6A	SKCM	chr16	24815594	24815594	A	T	Missense_Mutation	p.Q1264L	1
TNRC6A	STAD	chr16	24762058	24762060	AAG	-	In_Frame_Del	p.22_22del	1
TNRC6A	BLCA	chr16	24808846	24808846	G	A	Silent		1
TNRC6A	LGG	chr16	24801111	24801111	C	A	Missense_Mutation		1
TNRC6A	STAD	chr16	24806025	24806025	G	T	Missense_Mutation	p.K1171N	1
TNRC6A	BLCA	chr16	24826603	24826603	C	G	Missense_Mutation		1
TNRC6A	THYM	chr16	24834851	24834851	G	A	Missense_Mutation	p.G1871D	1
TNRC6A	LIHC	chr16	24835047	24835047	C	-	Frame_Shift_Del	p.D1936fs	1
TNRC6A	MESO	chr16	24788482	24788482	G	A	Missense_Mutation	p.R131Q	1
TNRC6A	COAD	chr16	24802967	24802967	G	A	Missense_Mutation	p.D1002N	1
TNRC6A	PAAD	chr16	24831545	24831545	G	A	Silent	p.L1722L	1
TNRC6A	HNSC	chr16	24831573	24831573	C	A	Missense_Mutation		1
TNRC6A	HNSC	chr16	24834300	24834300	G	C	Missense_Mutation		1
TNRC6A	SKCM	chr16	24834197	24834197	C	T	Silent	p.I1792I	1
TNRC6A	KIRP	chr16	24826534	24826534	G	A	Missense_Mutation		1
TNRC6A	CESC	chr16	24828149	24828149	G	T	Missense_Mutation		1
TNRC6A	UCEC	chr16	24801151	24801151	T	C	Silent	p.S396S	1
TNRC6A	LUAD	chr16	24801439	24801439	G	T	Missense_Mutation	p.Q492H	1
TNRC6A	LUAD	chr16	24804889	24804890	-	G	Frame_Shift_Ins	p.G1091fs	1
TNRC6A	DLBC	chr16	24804956	24804956	C	A	Missense_Mutation	p.A1113E	1
TNRC6A	READ	chr16	24816116	24816116	C	G	Missense_Mutation	p.Q1310E	1
TNRC6A	HNSC	chr16	24834300	24834300	G	C	Missense_Mutation	p.E1827Q	1
TNRC6A	SKCM	chr16	24831632	24831632	C	T	Silent	p.P1751P	1
TNRC6A	LGG	chr16	24828136	24828136	G	A	Splice_Site		1
TNRC6A	BLCA	chr16	24802526	24802526	G	A	Missense_Mutation		1
TNRC6A	KIRP	chr16	24801625	24801625	C	G	Silent	p.G554G	1
TNRC6A	LGG	chr16	24815620	24815620	C	T	Missense_Mutation		1
TNRC6A	STAD	chr16	24762058	24762060	AAG	-	In_Frame_Del	p.Q22del	1
TNRC6A	BLCA	chr16	24808841	24808841	G	C	Missense_Mutation		1
TNRC6A	LIHC	chr16	24801289	24801289	A	G	Silent		1
TNRC6A	LIHC	chr16	24762082	24762082	A	-	Frame_Shift_Del	p.E30fs	1
TNRC6A	OV	chr16	24709047	24709047	A	G	Missense_Mutation		1
TNRC6A	ESCA	chr16	24815566	24815566	G	T	Missense_Mutation	p.V1255F	1
TNRC6A	SARC	chr16	24815560	24815560	C	T	Nonsense_Mutation		1
TNRC6A	COAD	chr16	24804909	24804909	G	T	Silent	p.A1097A	1
TNRC6A	HNSC	chr16	24816384	24816384	G	A	Missense_Mutation		1
TNRC6A	SKCM	chr16	24802246	24802246	T	G	Missense_Mutation	p.F761L	1
TNRC6A	KIRP	chr16	24788620	24788620	C	G	Missense_Mutation		1
TNRC6A	CESC	chr16	24802308	24802308	G	T	Missense_Mutation		1
TNRC6A	LIHC	chr16	24801289	24801289	A	G	Silent	p.Q442Q	1
TNRC6A	CESC	chr16	24809285	24809285	G	T	Missense_Mutation		1
TNRC6A	LUAD	chr16	24800787	24800787	A	C	Missense_Mutation	p.N275T	1
TNRC6A	ESCA	chr16	24788375	24788375	A	G	Silent	p.P95	1
TNRC6A	READ	chr16	24826591	24826591	C	T	Missense_Mutation	p.S1599L	1
TNRC6A	SKCM	chr16	24803029	24803029	G	A	Nonsense_Mutation	p.W1022*	1
TNRC6A	LGG	chr16	24788379	24788379	C	T	Nonsense_Mutation	p.Q97*	1
TNRC6A	LIHC	chr16	24801737	24801737	G	A	Missense_Mutation		1
TNRC6A	STAD	chr16	24788376	24788381	CAGCAG	-	In_Frame_Del	p.QQ102del	1
TNRC6A	LIHC	chr16	24802369	24802369	G	A	Silent		1
TNRC6A	THYM	chr16	24818020	24818021	TT	-	Frame_Shift_Del	p.1485_1485del	1
TNRC6A	LIHC	chr16	24818039	24818039	C	-	Frame_Shift_Del	p.P1492fs	1
TNRC6A	OV	chr16	24725471	24725471	C	T	Nonsense_Mutation	p.Q1469*	1
TNRC6A	ESCA	chr16	24802699	24802699	A	T	Missense_Mutation		1
TNRC6A	SARC	chr16	24788423	24788434	GCAGCCACAGCC	-	In_Frame_Del	p.PQPQ115in_frame_del	1
TNRC6A	COAD	chr16	24828176	24828176	T	C	Missense_Mutation	p.I1624T	1
TNRC6A	HNSC	chr16	24802886	24802887	-	-	Frame_Shift_Ins		1
TNRC6A	SKCM	chr16	24834902	24834902	C	T	Missense_Mutation	p.S1888F	1
TNRC6A	LGG	chr16	24800571	24800571	C	G	Nonsense_Mutation	p.S203X	1
TNRC6A	STAD	chr16	24815592	24815592	T	C	Silent	p.P1263P	1
TNRC6A	BLCA	chr16	24808846	24808846	G	A	Silent	p.A1199A	1
TNRC6A	LIHC	chr16	24801444	24801444	A	G	Missense_Mutation	p.Q494R	1
TNRC6A	LUAD	chr16	24835027	24835027	G	T	Missense_Mutation	p.G1930C	1
TNRC6A	LUAD	chr16	24804889	24804890	-	G	Frame_Shift_Ins	p.W1091fs	1
TNRC6A	READ	chr16	24820776	24820776	C	A	Missense_Mutation	p.S1549Y	1
TNRC6A	STAD	chr16	24807240	24807240	A	-	Frame_Shift_Del		1
TNRC6A	LGG	chr16	24801111	24801111	C	A	Missense_Mutation	p.P383H	1
TNRC6A	BLCA	chr16	24820766	24820766	G	T	Missense_Mutation		1
TNRC6A	KIRP	chr16	24801182	24801182	A	G	Missense_Mutation	p.I407V	1
TNRC6A	LIHC	chr16	24801508	24801508	A	G	Silent		1
TNRC6A	BLCA	chr16	24805971	24805971	T	C	Silent		1
TNRC6A	LIHC	chr16	24826592	24826592	G	A	Silent	p.S1599S	1
TNRC6A	THYM	chr16	24834791	24834791	C	T	Missense_Mutation	p.A1851V	1
TNRC6A	LIHC	chr16	24834206	24834206	A	-	Frame_Shift_Del	p.S1795fs	1
TNRC6A	COAD	chr16	24788590	24788590	A	C	Missense_Mutation	p.K167T	1
TNRC6A	OV	chr16	24725061	24725061	C	T	Nonsense_Mutation	p.Q1429*	1
TNRC6A	GBM	chr16	24802455	24802455	A	C	Missense_Mutation		1
TNRC6A	SKCM	chr16	24803029	24803029	G	A	Nonsense_Mutation	p.W1022X	1
TNRC6A	COAD	chr16	24829970	24829970	C	T	Missense_Mutation	p.R1677C	1
TNRC6A	PRAD	chr16	24808870	24808870	G	A	Silent	p.Q1207Q	1
TNRC6A	HNSC	chr16	24800997	24800997	G	C	Missense_Mutation		1
TNRC6A	SKCM	chr16	24834284	24834284	C	T	Silent	p.V1821V	1
TNRC6A	BLCA	chr16	24802526	24802526	G	A	Missense_Mutation	p.D855N	1
TNRC6A	UCEC	chr16	24800695	24800695	C	T	Silent	p.G244G	1
TNRC6A	LUAD	chr16	24834925	24834925	G	A	Missense_Mutation	p.D1896N	1
TNRC6A	LUSC	chr16	24831651	24831651	T	A	Missense_Mutation	p.W1758R	1
TNRC6A	READ	chr16	24831490	24831490	C	T	Missense_Mutation	p.S1704F	1
TNRC6A	HNSC	chr16	24802886	24802887	-	T	Frame_Shift_Ins	p.T975fs	1
TNRC6A	STAD	chr16	24802902	24802904	AAG	-	In_Frame_Del		1
TNRC6A	LGG	chr16	24815620	24815620	C	T	Missense_Mutation	p.R1273C	1
TNRC6A	BLCA	chr16	24800967	24800967	C	T	Missense_Mutation		1
TNRC6A	KIRP	chr16	24788401	24788401	C	A	Missense_Mutation	p.P104Q	1
TNRC6A	STAD	chr16	24831653	24831653	G	A	Nonsense_Mutation	p.W1758X	1
TNRC6A	TGCT	chr16	24801979	24801979	C	T	Silent		1
TNRC6A	LIHC	chr16	24834981	24834981	C	T	Silent	p.H1914H	1
TNRC6A	THYM	chr16	24788471	24788471	G	T	Missense_Mutation	p.Q127H	1
TNRC6A	LIHC	chr16	24835104	24835104	G	-	Frame_Shift_Del	p.L1955fs	1
TNRC6A	COAD	chr16	24788645	24788645	T	A	Missense_Mutation	p.N185K	1
TNRC6A	OV	chr16	24710436	24710436	C	A	Missense_Mutation	p.S991Y	1
TNRC6A	HNSC	chr16	24800634	24800634	A	T	Missense_Mutation		1
TNRC6A	COAD	chr16	24831665	24831665	C	T	Silent	p.D1762D	1
TNRC6A	PRAD	chr16	24801364	24801364	C	T	Silent	p.S467S	1
TNRC6A	HNSC	chr16	24802394	24802394	A	G	Missense_Mutation		1
TNRC6A	HNSC	chr16	24833454	24833454	A	G	Missense_Mutation	p.N1787D	1
TNRC6A	SKCM	chr16	24802845	24802845	C	T	Missense_Mutation	p.A961V	1
TNRC6A	LGG	chr16	24788379	24788379	C	T	Nonsense_Mutation	p.Q97X	1
TNRC6A	BLCA	chr16	24788347	24788347	A	G	Missense_Mutation		1
TNRC6A	LIHC	chr16	24834848	24834848	C	A	Missense_Mutation	p.P1870H	1
TNRC6A	UCEC	chr16	24802006	24802006	C	T	Silent	p.R681R	1
TNRC6A	LUAD	chr16	24802810	24802810	A	T	Missense_Mutation	p.Q949H	1
TNRC6A	LUAD	chr16	24800859	24800859	G	T	Missense_Mutation	p.S299I	1
TNRC6A	CESC	chr16	24805874	24805874	C	G	Missense_Mutation	p.S1121C	1
TNRC6A	LUSC	chr16	24788444	24788444	G	T	Missense_Mutation	p.Q118H	1
TNRC6A	ESCA	chr16	24834982	24834982	G	T	Missense_Mutation	p.G1915C	1
TNRC6A	SARC	chr16	24802185	24802185	G	T	Missense_Mutation		1
TNRC6A	HNSC	chr16	24801106	24801106	A	G	Silent	p.K381K	1
TNRC6A	STAD	chr16	24816407	24816407	C	G	Missense_Mutation		1
TNRC6A	BLCA	chr16	24802802	24802802	A	G	Missense_Mutation		1
TNRC6A	LIHC	chr16	24805973	24805973	G	A	Missense_Mutation		1
TNRC6A	BLCA	chr16	24816096	24816096	C	T	Missense_Mutation		1
TNRC6A	LIHC	chr16	24826473	24826473	A	C	Missense_Mutation	p.I1560L	1
TNRC6A	THYM	chr16	24806011	24806011	C	T	Missense_Mutation	p.P1167S	1
TNRC6A	LUAD	chr16	24788604	24788604	C	G	Missense_Mutation	p.Q172E	1
TNRC6A	COAD	chr16	24800755	24800756	AG	-	Frame_Shift_Del	p.264_264del	1
TNRC6A	OV	chr16	24801413	24801413	C	T	Missense_Mutation	p.R484C	1
TNRC6A	HNSC	chr16	24804954	24804954	A	T	Missense_Mutation		1
TNRC6A	COAD	chr16	24834233	24834233	C	T	Silent	p.H1804H	1
TNRC6A	PRAD	chr16	24801953	24801953	G	A	Missense_Mutation	p.A664T	1
TNRC6A	SKCM	chr16	24808856	24808856	C	T	Missense_Mutation	p.P1203S	1
TNRC6A	BLCA	chr16	24788645	24788645	T	A	Missense_Mutation		1
TNRC6A	LIHC	chr16	24788418	24788441	CAGCAGCAGCCACAGCCGCAGCCG	-	In_Frame_Del	p.109_117del	1
TNRC6A	LUAD	chr16	24815581	24815581	G	T	Missense_Mutation	p.G1260C	1
TNRC6A	BLCA	chr16	24801809	24801809	G	C	Missense_Mutation		1
TNRC6A	BLCA	chr16	24805971	24805971	T	C	Silent	p.N1153N	1
TNRC6A	TGCT	chr16	24826529	24826529	C	T	Silent	p.N1578N	1
TNRC6A	LUAD	chr16	24788543	24788543	G	C	Missense_Mutation	p.R151S	1
TNRC6A	CESC	chr16	24826503	24826503	C	T	Missense_Mutation	p.P1570S	1
TNRC6A	LUSC	chr16	24801321	24801321	C	A	Missense_Mutation	p.P453Q	1
TNRC6A	SARC	chr16	24831519	24831519	G	T	Missense_Mutation		1
TNRC6A	HNSC	chr16	24802886	24802887	-	T	Frame_Shift_Ins	p.I975fs	1
TNRC6A	STAD	chr16	24802902	24802904	AAG	-	In_Frame_Del	p.KE980del	1
TNRC6A	KIRP	chr16	24801496	24801496	G	A	Silent	p.E511E	1
TNRC6A	BLCA	chr16	24818054	24818054	G	A	Missense_Mutation		1
TNRC6A	LIHC	chr16	24818081	24818081	A	G	Missense_Mutation	p.N1506D	1
TNRC6A	THYM	chr16	24818020	24818021	TT	-	Frame_Shift_Del	p.SF1485fs	1
TNRC6A	COAD	chr16	24801465	24801465	G	T	Missense_Mutation	p.G501V	1
TNRC6A	OV	chr16	24803028	24803029	GG	TT	Missense_Mutation	p.W1022F	1
TNRC6A	HNSC	chr16	24834933	24834933	T	A	Missense_Mutation		1
TNRC6A	COAD	chr16	24835018	24835018	A	G	Missense_Mutation	p.S1927G	1
TNRC6A	READ	chr16	24788505	24788505	C	T	Nonsense_Mutation	p.R139X	1
TNRC6A	HNSC	chr16	24801106	24801106	A	G	Silent		1
TNRC6A	SKCM	chr16	24802181	24802181	C	T	Missense_Mutation	p.P740S	1
TNRC6A	BLCA	chr16	24815594	24815594	A	G	Missense_Mutation		1
TNRC6A	BLCA	chr16	24820728	24820728	C	G	Nonsense_Mutation	p.S1533*	1
TNRC6A	UCEC	chr16	24800814	24800814	G	A	Missense_Mutation	p.R284Q	1
TNRC6A	LUAD	chr16	24831611	24831611	G	T	Missense_Mutation	p.L1744F	1
TNRC6A	BLCA	chr16	24803020	24803020	G	A	Silent		1
TNRC6A	THCA	chr16	24834233	24834233	C	T	Silent		1
TNRC6A	LIHC	chr16	24769670	24769670	A	-	Frame_Shift_Del	p.Q51fs	1
TNRC6A	LUAD	chr16	24805965	24805965	G	A	Missense_Mutation	p.M1151I	1
TNRC6A	CESC	chr16	24800641	24800641	G	A	Silent	p.K226	1
TNRC6A	LUSC	chr16	24802560	24802560	G	T	Missense_Mutation	p.W866L	1
TNRC6A	SARC	chr16	24831527	24831527	G	T	Missense_Mutation		1
TNRC6A	KICH	chr16	24817998	24817998	T	C	Missense_Mutation	p.L1478P	1
TNRC6A	STAD	chr16	24801392	24801392	A	G	Missense_Mutation	p.S477G	1
TNRC6A	STAD	chr16	24818069	24818069	C	T	Missense_Mutation	p.P1502S	1
TNRC6A	LIHC	chr16	24834278	24834278	T	C	Silent	p.A1819A	1
TNRC6A	THYM	chr16	24788444	24788444	G	A	Silent	p.Q118	1
TNRC6A	LUAD	chr16	24802765	24802765	G	T	Missense_Mutation	p.W934C	1
TNRC6A	COAD	chr16	24801737	24801737	G	A	Missense_Mutation	p.A592T	1
TNRC6A	OV	chr16	24804800	24804800	G	T	Missense_Mutation	p.G1061V	1
TNRC6A	HNSC	chr16	24801674	24801674	G	A	Missense_Mutation		1
TNRC6A	READ	chr16	24788511	24788511	C	T	Missense_Mutation	p.R141C	1
TNRC6A	HNSC	chr16	24833454	24833454	A	G	Missense_Mutation		1
TNRC6A	SKCM	chr16	24802182	24802182	C	T	Missense_Mutation	p.P740L	1
TNRC6A	BLCA	chr16	24802802	24802802	A	G	Missense_Mutation	p.N947D	1
TNRC6A	LIHC	chr16	24815534	24815534	A	G	Missense_Mutation	p.H1244R	1
TNRC6A	UCEC	chr16	24800899	24800899	A	G	Silent	p.P312P	1
TNRC6A	BLCA	chr16	24816096	24816096	C	T	Missense_Mutation	p.S1303L	1
TNRC6A	THYM	chr16	24801109	24801109	G	T	Silent		1
TNRC6A	LIHC	chr16	24800905	24800905	T	-	Frame_Shift_Del	p.G314fs	1
TNRC6A	CESC	chr16	24835021	24835021	C	A	Missense_Mutation	p.L1928M	1
TNRC6A	LUSC	chr16	24801959	24801959	A	G	Missense_Mutation	p.T666A	1
TNRC6A	ESCA	chr16	24834982	24834982	G	T	Missense_Mutation		1
TNRC6A	SARC	chr16	24801720	24801720	G	T	Missense_Mutation		1
TNRC6A	STAD	chr16	24831653	24831653	G	A	Nonsense_Mutation	p.W1758*	1
TNRC6A	SKCM	chr16	24831512	24831512	C	T	Silent	p.T1711T	1
TNRC6A	BLCA	chr16	24788436	24788436	C	T	Nonsense_Mutation	p.Q116*	1
TNRC6A	UCEC	chr16	24801085	24801085	G	A	Silent	p.E374E	1
TNRC6A	COAD	chr16	24802132	24802132	G	T	Missense_Mutation	p.W723C	1
TNRC6A	PAAD	chr16	24788408	24788408	G	T	Missense_Mutation		1
TNRC6A	HNSC	chr16	24802355	24802355	T	C	Missense_Mutation		1
TNRC6A	LUAD	chr16	24802337	24802337	T	C	Missense_Mutation	p.W792R	1
TNRC6A	DLBC	chr16	24788401	24788402	-	GCA	In_Frame_Ins	p.P104delinsPQ	1
TNRC6A	READ	chr16	24788528	24788528	A	C	Missense_Mutation	p.K146N	1
TNRC6A	HNSC	chr16	24835045	24835045	G	A	Missense_Mutation		1
TNRC6A	SKCM	chr16	24829927	24829927	C	T	Silent	p.S1662S	1
TNRC6A	STAD	chr16	24788376	24788381	CAGCAG	-	In_Frame_Del	p.95_97del	1
TNRC6A	BLCA	chr16	24802299	24802299	C	T	Missense_Mutation		1
TNRC6A	BLCA	chr16	24801809	24801809	G	C	Missense_Mutation	p.E616Q	1
TNRC6A	LIHC	chr16	24802005	24802005	G	T	Missense_Mutation	p.R681L	1
TNRC6A	STAD	chr16	24815588	24815588	G	A	Missense_Mutation	p.R1262Q	1
TNRC6A	BLCA	chr16	24802435	24802435	G	C	Missense_Mutation		1
TNRC6A	BLCA	chr16	24818054	24818054	G	A	Missense_Mutation	p.E1497K	1
TNRC6A	LIHC	chr16	24762093	24762093	A	-	Frame_Shift_Del	p.K35fs	1
TNRC6A	LUSC	chr16	24788259	24788259	G	C	Missense_Mutation	p.E57Q	1
TNRC6A	SARC	chr16	24833408	24833408	G	T	Missense_Mutation		1
TNRC6A	STAD	chr16	24802902	24802904	AAG	-	In_Frame_Del	p.980_980del	1

Copy number variation (CNV) of TNRC6A
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across TNRC6A
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
98852	BRCA	TCGA-S3-AA0Z-01A	ARHGAP17	chr16	24953308	-	TNRC6A	chr16	24762047	+
98852	N/A	AA507348	ATF2	chr2	175936987	-	TNRC6A	chr16	24730973	+
98852	N/A	N22604	ATXN2	chr12	112010838	-	TNRC6A	chr16	24837543	-
98852	N/A	EC527969	CACNG3	chr16	24346112	+	TNRC6A	chr16	24644105	+
98852	N/A	BF437094	CLN8	chr8	1711096	+	TNRC6A	chr16	24802241	-
98852	GBM	TCGA-06-0211-01B	CSNK2A1	chr20	485762	-	TNRC6A	chr16	24788254	+
98852	N/A	AA531082	GALNTL6	chr4	172884246	+	TNRC6A	chr16	24741835	-
98852	HNSC	TCGA-BA-6869-01A	PDLIM1	chr10	97023621	-	TNRC6A	chr16	24800553	+
98852	N/A	BF920959	RNF112	chr17	19320049	-	TNRC6A	chr16	24790369	+
98852	N/A	CV353496	SLC9A9	chr3	143030963	+	TNRC6A	chr16	24769851	-
98852	N/A	BF733944	SMG6	chr17	2203379	+	TNRC6A	chr16	24802489	-
98852	N/A	AK025277	SORBS2	chr4	186610266	-	TNRC6A	chr16	24828954	+
98852	N/A	AA962358	STRN4	chr19	47222828	+	TNRC6A	chr16	24756977	-
98852	N/A	BI491476	TCF7L1	chr2	85446844	+	TNRC6A	chr16	24734039	-
98852	N/A	BF839733	TG	chr8	134025682	-	TNRC6A	chr16	24831390	-
92857	N/A	BI046776	TNRC6A	chr16	24770977	+	ACTG2	chr2	74129762	-
95742	N/A	AA653866	TNRC6A	chr16	24746555	-	ADAMTS9-AS2	chr3	64827552	-
92857	LUAD	TCGA-69-A59K-01A	TNRC6A	chr16	24802355	+	ANKS4B	chr16	21262929	+
92857	N/A	N64162	TNRC6A	chr16	24643092	-	FTH1P10	chr5	17353804	+
92857	OV	TCGA-13-0765	TNRC6A	chr16	24741621	+	LCMT1	chr16	25139795	+
92857	OV	TCGA-13-0765	TNRC6A	chr16	24762134	+	LCMT1	chr16	25139795	+
92857	OV	TCGA-13-0765-01A	TNRC6A	chr16	24741621	+	LCMT1	chr16	25139796	+
92857	OV	TCGA-13-0765-01A	TNRC6A	chr16	24762134	+	LCMT1	chr16	25066140	+
92857	OV	TCGA-13-0765-01A	TNRC6A	chr16	24762134	+	LCMT1	chr16	25137285	+
92857	OV	TCGA-13-0765-01A	TNRC6A	chr16	24762134	+	LCMT1	chr16	25139796	+
95786	PCPG	TCGA-TT-A6YN	TNRC6A	chr16	24809287	+	LIX1L	chr1	145492234	+
95786	PCPG	TCGA-TT-A6YN-01A	TNRC6A	chr16	24809287	+	LIX1L	chr1	145492235	-
97011	LUSC	TCGA-O2-A52S-01A	TNRC6A	chr16	24741167	+	METTL9	chr16	21666548	+
97631	GBM	TCGA-06-0882-01A	TNRC6A	chr16	24741621	+	PRKCB	chr16	24192111	+
92857	N/A	BE175576	TNRC6A	chr16	24813992	-	RPA1	chr17	1782975	-
98852	N/A	AA501799	TNRC6A	chr16	24780527	+	TNRC6A	chr16	24780356	-
98852	N/A	AV730574	WDFY4	chr10	50000063	-	TNRC6A	chr16	24816958	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
PCPG	TNRC6A	0.00238143665653013	0.067
TGCT	TNRC6A	0.0185447807146848	0.5
SARC	TNRC6A	0.0273874462783429	0.71

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	TNRC6A	0.0323646821186705	1
BLCA	TNRC6A	0.0226469949338202	0.72
SARC	TNRC6A	0.0059899877017452	0.2

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C0014550	Myoclonic Epilepsy	1	CTD_human
C0338478	Idiopathic Myoclonic Epilepsy	1	CTD_human
C0338479	Symptomatic Myoclonic Epilepsy	1	CTD_human
C0393695	Early Childhood Epilepsy, Myoclonic	1	CTD_human
C0393702	Myoclonic Astatic Epilepsy	1	CTD_human
C0393703	Myoclonic Absence Epilepsy	1	CTD_human
C0438414	Myoclonic Encephalopathy	1	CTD_human
C0751120	Benign Infantile Myoclonic Epilepsy	1	CTD_human
C0751122	Infantile Severe Myoclonic Epilepsy	1	CTD_human
C0917800	Epilepsy, Myoclonic, Infantile	1	CTD_human