Home

Download

Statistics

Examples

Help

Contact

	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPL42 (NCBI Gene ID:28977)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPL42
	Gene ID: 28977
	Gene Symbol	MRPL42
	Gene ID	28977
	Gene Name	mitochondrial ribosomal protein L42
	Synonyms	HSPC204\|L31MT\|L42MT\|MRP-L31\|MRP-L42\|MRP-S32\|MRPL31\|MRPS32\|PTD007\|RPML31\|S32MT
	Cytomap	12q22
	Type of Gene	protein-coding
	Description	39S ribosomal protein L42, mitochondrial28S ribosomal protein S32, mitochondrial39S ribosomal protein L31, mitochondrialmitochondrial large ribosomal subunit protein mL42
	Modification date	20200313
	UniProtAcc	Q9Y6G3

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
MRPL42	(733 - 1119.25]

Top

Translation Studies in PubMed

We searched PubMed using 'MRPL42[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPL42	.	.

Top

Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000552217	93862964	93863131	5CDS-5UTR
ENST00000549982	93870729	93870793	Frame-shift
ENST00000552217	93870729	93870793	Frame-shift
ENST00000549982	93873163	93873248	Frame-shift
ENST00000552217	93873163	93873248	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

Top

Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUAD	MRPL42	-6.34610249602491	2.48255276366547e-08
KIRC	MRPL42	-4.382095336248	5.26630854166927e-06

Top

Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
SARC	MRPL42	0.274705482	0.042418528

Top

Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPL42 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
COAD	Epifactor	MRPL42	UBE2N	0.824142343	9.88E-83
LUSC	Epifactor	MRPL42	UBE2N	0.801248723	5.27E-125
OV	Epifactor	MRPL42	UBE2N	0.836975221	4.15E-82
READ	Epifactor	MRPL42	UBE2N	0.834695867	1.93E-28
SKCM	Epifactor	MRPL42	ACTR6	0.819885857	2.14E-116
TGCT	Epifactor	MRPL42	HELLS	0.810988894	1.11E-37
UVM	Cell metabolism gene	MRPL42	XRN2	0.801036615	4.63E-19
UVM	Cell metabolism gene	MRPL42	FAR1	0.801235102	4.47E-19
UVM	Cell metabolism gene	MRPL42	AGPS	0.801676682	4.14E-19
UVM	Cell metabolism gene	MRPL42	NAMPT	0.801718612	4.10E-19
UVM	Cell metabolism gene	MRPL42	ETNK1	0.802295411	3.71E-19
UVM	Cell metabolism gene	MRPL42	GNPDA2	0.803065345	3.23E-19
UVM	Cell metabolism gene	MRPL42	PIGB	0.804422621	2.54E-19
UVM	Cell metabolism gene	MRPL42	C1GALT1C1	0.805993319	1.91E-19
UVM	Cell metabolism gene	MRPL42	SGPP1	0.806042106	1.90E-19
UVM	Cell metabolism gene	MRPL42	DLD	0.806323373	1.80E-19
UVM	Cell metabolism gene	MRPL42	SRP19	0.806856644	1.64E-19
UVM	Cell metabolism gene	MRPL42	VAPA	0.807209826	1.54E-19
UVM	Cell metabolism gene	MRPL42	FUT8	0.808087404	1.31E-19
UVM	Cell metabolism gene	MRPL42	PLA2G12A	0.808361692	1.24E-19
UVM	Cell metabolism gene	MRPL42	IDI1	0.809622005	9.87E-20
UVM	Cell metabolism gene	MRPL42	MDH1	0.809784212	9.58E-20
UVM	Cell metabolism gene	MRPL42	POLR2K	0.81140714	7.09E-20
UVM	Cell metabolism gene	MRPL42	SACM1L	0.811428204	7.06E-20
UVM	Cell metabolism gene	MRPL42	PIGA	0.813929177	4.41E-20
UVM	Cell metabolism gene	MRPL42	NUDT12	0.814233344	4.17E-20
UVM	Cell metabolism gene	MRPL42	PAFAH1B1	0.814234351	4.17E-20
UVM	Cell metabolism gene	MRPL42	DIS3	0.816235355	2.84E-20
UVM	Cell metabolism gene	MRPL42	PIK3C3	0.816655714	2.62E-20
UVM	Cell metabolism gene	MRPL42	ACSL4	0.816802601	2.55E-20
UVM	Cell metabolism gene	MRPL42	MED7	0.817203186	2.36E-20
UVM	Cell metabolism gene	MRPL42	GFPT1	0.81907103	1.64E-20
UVM	Cell metabolism gene	MRPL42	NANP	0.81931149	1.57E-20
UVM	Cell metabolism gene	MRPL42	PSMD12	0.819402621	1.54E-20
UVM	Cell metabolism gene	MRPL42	DLAT	0.819963318	1.38E-20
UVM	Cell metabolism gene	MRPL42	SEH1L	0.821357818	1.05E-20
UVM	Cell metabolism gene	MRPL42	SRP54	0.822609166	8.17E-21
UVM	Cell metabolism gene	MRPL42	GRPEL2	0.825678231	4.40E-21
UVM	Cell metabolism gene	MRPL42	CMAS	0.826836121	3.47E-21
UVM	Cell metabolism gene	MRPL42	MGAT2	0.827734662	2.89E-21
UVM	Cell metabolism gene	MRPL42	DCK	0.830069052	1.78E-21
UVM	Cell metabolism gene	MRPL42	PITPNB	0.830963044	1.47E-21
UVM	Cell metabolism gene	MRPL42	MED17	0.831745333	1.25E-21
UVM	Cell metabolism gene	MRPL42	UGGT2	0.831961818	1.19E-21
UVM	Cell metabolism gene	MRPL42	VBP1	0.833416121	8.75E-22
UVM	Cell metabolism gene	MRPL42	TIMM17A	0.835278042	5.86E-22
UVM	Cell metabolism gene	MRPL42	SRP72	0.83549048	5.60E-22
UVM	Cell metabolism gene	MRPL42	TRAM1	0.839204558	2.48E-22
UVM	Cell metabolism gene	MRPL42	CCT2	0.840029446	2.06E-22
UVM	Cell metabolism gene	MRPL42	MCEE	0.840283887	1.95E-22
UVM	Cell metabolism gene	MRPL42	SPTLC1	0.840704167	1.77E-22
UVM	Cell metabolism gene	MRPL42	HMGCR	0.841235157	1.57E-22
UVM	Cell metabolism gene	MRPL42	PRKAA1	0.842343564	1.22E-22
UVM	Cell metabolism gene	MRPL42	RAP1B	0.842586947	1.16E-22
UVM	Cell metabolism gene	MRPL42	EDEM3	0.842903463	1.08E-22
UVM	Cell metabolism gene	MRPL42	RPE	0.844482643	7.49E-23
UVM	Cell metabolism gene	MRPL42	PI4K2B	0.845215531	6.32E-23
UVM	Cell metabolism gene	MRPL42	CLOCK	0.846072328	5.18E-23
UVM	Cell metabolism gene	MRPL42	CNOT8	0.847749184	3.49E-23
UVM	Cell metabolism gene	MRPL42	LCLAT1	0.848491649	2.93E-23
UVM	Cell metabolism gene	MRPL42	MTMR6	0.849459527	2.33E-23
UVM	Cell metabolism gene	MRPL42	IMPA1	0.850447243	1.83E-23
UVM	Cell metabolism gene	MRPL42	AZIN1	0.851316097	1.49E-23
UVM	Cell metabolism gene	MRPL42	EPT1	0.852004659	1.26E-23
UVM	Cell metabolism gene	MRPL42	PHAX	0.852455738	1.13E-23
UVM	Cell metabolism gene	MRPL42	POLR2B	0.852508536	1.11E-23
UVM	Cell metabolism gene	MRPL42	GPD2	0.853604108	8.50E-24
UVM	Cell metabolism gene	MRPL42	PSMC6	0.853819379	8.06E-24
UVM	Cell metabolism gene	MRPL42	BPNT1	0.854173964	7.39E-24
UVM	Cell metabolism gene	MRPL42	SLC25A32	0.857402472	3.29E-24
UVM	Cell metabolism gene	MRPL42	ARFGEF2	0.864555608	5.09E-25
UVM	Cell metabolism gene	MRPL42	PSME4	0.865997707	3.45E-25
UVM	Cell metabolism gene	MRPL42	PIK3C2A	0.866647629	2.89E-25
UVM	Cell metabolism gene	MRPL42	PANK3	0.87107848	8.45E-26
UVM	Cell metabolism gene	MRPL42	PSMA4	0.874479802	3.19E-26
UVM	Cell metabolism gene	MRPL42	PPAT	0.880807431	4.80E-27
UVM	Cell metabolism gene	MRPL42	PSMD14	0.884104086	1.71E-27
UVM	Cell metabolism gene	MRPL42	NUP50	0.884223859	1.65E-27
UVM	Cell metabolism gene	MRPL42	XPO1	0.886650206	7.58E-28
UVM	Cell metabolism gene	MRPL42	TGS1	0.889124009	3.36E-28
UVM	Cell metabolism gene	MRPL42	TNPO1	0.891453909	1.54E-28
UVM	Cell metabolism gene	MRPL42	LYPLA1	0.892240077	1.18E-28
UVM	CGC	MRPL42	ITGAV	0.800368592	5.20E-19
UVM	CGC	MRPL42	STAG2	0.801492593	4.27E-19
UVM	CGC	MRPL42	POT1	0.801503865	4.26E-19
UVM	CGC	MRPL42	ETNK1	0.802295411	3.71E-19
UVM	CGC	MRPL42	AFF4	0.80233152	3.68E-19
UVM	CGC	MRPL42	MSH2	0.803195591	3.16E-19
UVM	CGC	MRPL42	ARID2	0.804188098	2.65E-19
UVM	CGC	MRPL42	TCF12	0.810057693	9.11E-20
UVM	CGC	MRPL42	PWWP2A	0.817035451	2.44E-20
UVM	CGC	MRPL42	EZH2	0.817698925	2.14E-20
UVM	CGC	MRPL42	UBR5	0.825824475	4.27E-21
UVM	CGC	MRPL42	ABI1	0.829694371	1.92E-21
UVM	CGC	MRPL42	RAD17	0.830587126	1.59E-21
UVM	CGC	MRPL42	SF3B1	0.833653759	8.32E-22
UVM	CGC	MRPL42	TOP1	0.833711865	8.22E-22
UVM	CGC	MRPL42	TCEA1	0.835240363	5.91E-22
UVM	CGC	MRPL42	ZMYM2	0.835900488	5.12E-22
UVM	CGC	MRPL42	KRAS	0.836795122	4.21E-22
UVM	CGC	MRPL42	USP8	0.837270552	3.80E-22
UVM	CGC	MRPL42	PMS1	0.837505197	3.60E-22
UVM	CGC	MRPL42	GOLGA5	0.838344293	3.00E-22
UVM	CGC	MRPL42	CUL3	0.839139106	2.51E-22
UVM	CGC	MRPL42	JAK2	0.843763798	8.83E-23
UVM	CGC	MRPL42	FBXO11	0.84470808	7.11E-23
UVM	CGC	MRPL42	BAZ1A	0.849644626	2.22E-23
UVM	CGC	MRPL42	CREB1	0.850859618	1.66E-23
UVM	CGC	MRPL42	SUZ12	0.850936891	1.63E-23
UVM	CGC	MRPL42	ATM	0.850967712	1.62E-23
UVM	CGC	MRPL42	KIF5B	0.85919082	2.08E-24
UVM	CGC	MRPL42	CDC73	0.860856668	1.35E-24
UVM	CGC	MRPL42	BMPR1A	0.86319147	7.33E-25
UVM	CGC	MRPL42	RAD21	0.866347197	3.14E-25
UVM	CGC	MRPL42	NBN	0.878678175	9.18E-27
UVM	CGC	MRPL42	RABEP1	0.880234066	5.72E-27
UVM	CGC	MRPL42	XPO1	0.886650206	7.58E-28
UVM	Epifactor	MRPL42	PCGF6	0.800756536	4.86E-19
UVM	Epifactor	MRPL42	ATF2	0.801015599	4.65E-19
UVM	Epifactor	MRPL42	ZRANB3	0.801812437	4.04E-19
UVM	Epifactor	MRPL42	SUDS3	0.802008566	3.90E-19
UVM	Epifactor	MRPL42	BRWD3	0.803162941	3.18E-19
UVM	Epifactor	MRPL42	ARID2	0.804188098	2.65E-19
UVM	Epifactor	MRPL42	DNTTIP2	0.804996384	2.29E-19
UVM	Epifactor	MRPL42	SMARCAD1	0.807522484	1.45E-19
UVM	Epifactor	MRPL42	PARG	0.809428453	1.02E-19
UVM	Epifactor	MRPL42	INO80D	0.809895351	9.39E-20
UVM	Epifactor	MRPL42	CUL5	0.810878082	7.82E-20
UVM	Epifactor	MRPL42	YEATS4	0.811458238	7.02E-20
UVM	Epifactor	MRPL42	RAD54B	0.81621046	2.86E-20
UVM	Epifactor	MRPL42	EZH2	0.817698925	2.14E-20
UVM	Epifactor	MRPL42	JMJD1C	0.819115486	1.63E-20
UVM	Epifactor	MRPL42	YY1	0.819557702	1.49E-20
UVM	Epifactor	MRPL42	NSL1	0.820903968	1.15E-20
UVM	Epifactor	MRPL42	BRMS1L	0.821249436	1.07E-20
UVM	Epifactor	MRPL42	HMGB1	0.821389947	1.04E-20
UVM	Epifactor	MRPL42	ANP32E	0.824198598	5.94E-21
UVM	Epifactor	MRPL42	EPC2	0.825809973	4.28E-21
UVM	Epifactor	MRPL42	UBR5	0.825824475	4.27E-21
UVM	Epifactor	MRPL42	BRCC3	0.826352352	3.83E-21
UVM	Epifactor	MRPL42	TLK1	0.826467121	3.75E-21
UVM	Epifactor	MRPL42	ATAD2B	0.828982691	2.23E-21
UVM	Epifactor	MRPL42	SF3B1	0.833653759	8.32E-22
UVM	Epifactor	MRPL42	SMEK1	0.834640596	6.73E-22
UVM	Epifactor	MRPL42	ZMYM2	0.835900488	5.12E-22
UVM	Epifactor	MRPL42	USP15	0.83754157	3.58E-22
UVM	Epifactor	MRPL42	FAM175B	0.837830358	3.36E-22
UVM	Epifactor	MRPL42	CUL3	0.839139106	2.51E-22
UVM	Epifactor	MRPL42	CHUK	0.839647852	2.24E-22
UVM	Epifactor	MRPL42	PRKAA1	0.842343564	1.22E-22
UVM	Epifactor	MRPL42	JAK2	0.843763798	8.83E-23
UVM	Epifactor	MRPL42	TAF7	0.843866841	8.63E-23
UVM	Epifactor	MRPL42	TDG	0.845532532	5.87E-23
UVM	Epifactor	MRPL42	CLOCK	0.846072328	5.18E-23
UVM	Epifactor	MRPL42	MASTL	0.846400442	4.79E-23
UVM	Epifactor	MRPL42	BAZ1A	0.849644626	2.22E-23
UVM	Epifactor	MRPL42	CUL2	0.850772528	1.70E-23
UVM	Epifactor	MRPL42	SUZ12	0.850936891	1.63E-23
UVM	Epifactor	MRPL42	ATM	0.850967712	1.62E-23
UVM	Epifactor	MRPL42	SMARCA5	0.854294657	7.17E-24
UVM	Epifactor	MRPL42	ACTR6	0.855182597	5.75E-24
UVM	Epifactor	MRPL42	CBX3	0.855884051	4.82E-24
UVM	Epifactor	MRPL42	RLIM	0.85928851	2.03E-24
UVM	Epifactor	MRPL42	CDC73	0.860856668	1.35E-24
UVM	Epifactor	MRPL42	UCHL5	0.864214866	5.58E-25
UVM	Epifactor	MRPL42	AEBP2	0.868990643	1.52E-25
UVM	Epifactor	MRPL42	CDK17	0.871585596	7.32E-26
UVM	Epifactor	MRPL42	TAF2	0.872963005	4.94E-26
UVM	Epifactor	MRPL42	HAT1	0.874147044	3.51E-26
UVM	Epifactor	MRPL42	PHF20L1	0.875847938	2.13E-26
UVM	Epifactor	MRPL42	NBN	0.878678175	9.18E-27
UVM	Epifactor	MRPL42	SMEK2	0.891814044	1.36E-28
UVM	IUPHAR	MRPL42	ITGAV	0.800368592	5.20E-19
UVM	IUPHAR	MRPL42	EGLN1	0.800832093	4.80E-19
UVM	IUPHAR	MRPL42	NEK7	0.801517821	4.25E-19
UVM	IUPHAR	MRPL42	DYRK2	0.801928823	3.96E-19
UVM	IUPHAR	MRPL42	BRWD3	0.803162941	3.18E-19
UVM	IUPHAR	MRPL42	SGPP1	0.806042106	1.90E-19
UVM	IUPHAR	MRPL42	NIPAL2	0.806392264	1.78E-19
UVM	IUPHAR	MRPL42	ATP6V0A2	0.806442264	1.77E-19
UVM	IUPHAR	MRPL42	RPS6KC1	0.807972097	1.34E-19
UVM	IUPHAR	MRPL42	TAOK3	0.808167916	1.29E-19
UVM	IUPHAR	MRPL42	PLA2G12A	0.808361692	1.24E-19
UVM	IUPHAR	MRPL42	IDI1	0.809622005	9.87E-20
UVM	IUPHAR	MRPL42	PLK4	0.811136446	7.46E-20
UVM	IUPHAR	MRPL42	SLC30A9	0.813495084	4.79E-20
UVM	IUPHAR	MRPL42	ATP11C	0.814074751	4.29E-20
UVM	IUPHAR	MRPL42	SLC25A46	0.814428651	4.02E-20
UVM	IUPHAR	MRPL42	SLC30A6	0.815960122	3.00E-20
UVM	IUPHAR	MRPL42	PIK3C3	0.816655714	2.62E-20
UVM	IUPHAR	MRPL42	ATP2B1	0.817465241	2.24E-20
UVM	IUPHAR	MRPL42	EZH2	0.817698925	2.14E-20
UVM	IUPHAR	MRPL42	CYP51A1	0.817780604	2.11E-20
UVM	IUPHAR	MRPL42	JMJD1C	0.819115486	1.63E-20
UVM	IUPHAR	MRPL42	TNKS2	0.820266893	1.30E-20
UVM	IUPHAR	MRPL42	CSNK1G3	0.820808481	1.17E-20
UVM	IUPHAR	MRPL42	TMEM165	0.822588666	8.20E-21
UVM	IUPHAR	MRPL42	RIOK3	0.823009494	7.54E-21
UVM	IUPHAR	MRPL42	STK17A	0.823279764	7.14E-21
UVM	IUPHAR	MRPL42	TLK1	0.826467121	3.75E-21
UVM	IUPHAR	MRPL42	MAP3K2	0.827249401	3.19E-21
UVM	IUPHAR	MRPL42	ATAD2B	0.828982691	2.23E-21
UVM	IUPHAR	MRPL42	BMPR2	0.82915217	2.15E-21
UVM	IUPHAR	MRPL42	TOP1	0.833711865	8.22E-22
UVM	IUPHAR	MRPL42	KRAS	0.836795122	4.21E-22
UVM	IUPHAR	MRPL42	CHUK	0.839647852	2.24E-22
UVM	IUPHAR	MRPL42	RIOK2	0.839963691	2.09E-22
UVM	IUPHAR	MRPL42	SPTLC1	0.840704167	1.77E-22
UVM	IUPHAR	MRPL42	MAGT1	0.840868661	1.71E-22
UVM	IUPHAR	MRPL42	HMGCR	0.841235157	1.57E-22
UVM	IUPHAR	MRPL42	ADAM17	0.841958834	1.33E-22
UVM	IUPHAR	MRPL42	PRKAA1	0.842343564	1.22E-22
UVM	IUPHAR	MRPL42	NAPEPLD	0.842634076	1.14E-22
UVM	IUPHAR	MRPL42	JAK2	0.843763798	8.83E-23
UVM	IUPHAR	MRPL42	FBXO11	0.84470808	7.11E-23
UVM	IUPHAR	MRPL42	PI4K2B	0.845215531	6.32E-23
UVM	IUPHAR	MRPL42	CSNK1A1	0.845393873	6.06E-23
UVM	IUPHAR	MRPL42	CLOCK	0.846072328	5.18E-23
UVM	IUPHAR	MRPL42	MASTL	0.846400442	4.79E-23
UVM	IUPHAR	MRPL42	SLC30A5	0.84652158	4.66E-23
UVM	IUPHAR	MRPL42	XIAP	0.846954937	4.21E-23
UVM	IUPHAR	MRPL42	BAZ1A	0.849644626	2.22E-23
UVM	IUPHAR	MRPL42	IDE	0.85004527	2.02E-23
UVM	IUPHAR	MRPL42	IMPA1	0.850447243	1.83E-23
UVM	IUPHAR	MRPL42	ATM	0.850967712	1.62E-23
UVM	IUPHAR	MRPL42	ABCB10	0.852900807	1.01E-23
UVM	IUPHAR	MRPL42	SLC25A32	0.857402472	3.29E-24
UVM	IUPHAR	MRPL42	BMPR1A	0.86319147	7.33E-25
UVM	IUPHAR	MRPL42	TBK1	0.864547696	5.10E-25
UVM	IUPHAR	MRPL42	PIK3C2A	0.866647629	2.89E-25
UVM	IUPHAR	MRPL42	MAPK6	0.87008008	1.12E-25
UVM	IUPHAR	MRPL42	CDK17	0.871585596	7.32E-26
UVM	IUPHAR	MRPL42	ATP6V1C1	0.873939735	3.73E-26
UVM	IUPHAR	MRPL42	HAT1	0.874147044	3.51E-26
UVM	IUPHAR	MRPL42	STK3	0.878808639	8.83E-27
UVM	IUPHAR	MRPL42	PPAT	0.880807431	4.80E-27
UVM	IUPHAR	MRPL42	VRK2	0.880973655	4.56E-27
UVM	IUPHAR	MRPL42	PSMD14	0.884104086	1.71E-27
UVM	IUPHAR	MRPL42	XPO1	0.886650206	7.58E-28
UVM	IUPHAR	MRPL42	USP14	0.892124168	1.22E-28
UVM	IUPHAR	MRPL42	PRMT3	0.893162828	8.56E-29
UVM	IUPHAR	MRPL42	MAP4K3	0.893420827	7.83E-29
UVM	Kinase	MRPL42	NEK7	0.801517821	4.25E-19
UVM	Kinase	MRPL42	DYRK2	0.801928823	3.96E-19
UVM	Kinase	MRPL42	RPS6KC1	0.807972097	1.34E-19
UVM	Kinase	MRPL42	TAOK3	0.808167916	1.29E-19
UVM	Kinase	MRPL42	PLK4	0.811136446	7.46E-20
UVM	Kinase	MRPL42	CSNK1G3	0.820808481	1.17E-20
UVM	Kinase	MRPL42	RIOK3	0.823009494	7.54E-21
UVM	Kinase	MRPL42	STK17A	0.823279764	7.14E-21
UVM	Kinase	MRPL42	TLK1	0.826467121	3.75E-21
UVM	Kinase	MRPL42	MAP3K2	0.827249401	3.19E-21
UVM	Kinase	MRPL42	BMPR2	0.82915217	2.15E-21
UVM	Kinase	MRPL42	CHUK	0.839647852	2.24E-22
UVM	Kinase	MRPL42	RIOK2	0.839963691	2.09E-22
UVM	Kinase	MRPL42	PRKAA1	0.842343564	1.22E-22
UVM	Kinase	MRPL42	JAK2	0.843763798	8.83E-23
UVM	Kinase	MRPL42	CSNK1A1	0.845393873	6.06E-23
UVM	Kinase	MRPL42	MASTL	0.846400442	4.79E-23
UVM	Kinase	MRPL42	BAZ1A	0.849644626	2.22E-23
UVM	Kinase	MRPL42	ATM	0.850967712	1.62E-23
UVM	Kinase	MRPL42	BMPR1A	0.86319147	7.33E-25
UVM	Kinase	MRPL42	TBK1	0.864547696	5.10E-25
UVM	Kinase	MRPL42	MAPK6	0.87008008	1.12E-25
UVM	Kinase	MRPL42	CDK17	0.871585596	7.32E-26
UVM	Kinase	MRPL42	STK3	0.878808639	8.83E-27
UVM	Kinase	MRPL42	VRK2	0.880973655	4.56E-27
UVM	Kinase	MRPL42	MAP4K3	0.893420827	7.83E-29
UVM	TF	MRPL42	PCGF6	0.800756536	4.86E-19
UVM	TF	MRPL42	ZNF791	0.800810874	4.82E-19
UVM	TF	MRPL42	ATF2	0.801015599	4.65E-19
UVM	TF	MRPL42	ZNF33A	0.80158826	4.20E-19
UVM	TF	MRPL42	ZNF222	0.802309302	3.70E-19
UVM	TF	MRPL42	ZNF75D	0.802819751	3.38E-19
UVM	TF	MRPL42	ZNF701	0.803657332	2.91E-19
UVM	TF	MRPL42	ZNF441	0.803809676	2.83E-19
UVM	TF	MRPL42	CREM	0.803973638	2.75E-19
UVM	TF	MRPL42	ARID2	0.804188098	2.65E-19
UVM	TF	MRPL42	ZNF45	0.804249048	2.62E-19
UVM	TF	MRPL42	ZNF225	0.806621522	1.71E-19
UVM	TF	MRPL42	ZNF260	0.807574754	1.44E-19
UVM	TF	MRPL42	ZNF397	0.809038956	1.10E-19
UVM	TF	MRPL42	ZNF234	0.80919241	1.07E-19
UVM	TF	MRPL42	TCF12	0.810057693	9.11E-20
UVM	TF	MRPL42	ZNF680	0.810665238	8.14E-20
UVM	TF	MRPL42	ELK3	0.810911138	7.78E-20
UVM	TF	MRPL42	ZNF510	0.810988688	7.66E-20
UVM	TF	MRPL42	ZNF527	0.811359359	7.15E-20
UVM	TF	MRPL42	PRDM10	0.812291976	6.01E-20
UVM	TF	MRPL42	ZNF430	0.81266648	5.60E-20
UVM	TF	MRPL42	ZNF101	0.814774773	3.76E-20
UVM	TF	MRPL42	ZNF226	0.815270257	3.42E-20
UVM	TF	MRPL42	FOXN2	0.81579637	3.09E-20
UVM	TF	MRPL42	ZNF383	0.816906922	2.50E-20
UVM	TF	MRPL42	ZBTB10	0.817647215	2.17E-20
UVM	TF	MRPL42	ADNP2	0.819290971	1.57E-20
UVM	TF	MRPL42	YY1	0.819557702	1.49E-20
UVM	TF	MRPL42	ZNF140	0.820871609	1.15E-20
UVM	TF	MRPL42	ZNF800	0.821327592	1.05E-20
UVM	TF	MRPL42	ZNF546	0.822844386	7.79E-21
UVM	TF	MRPL42	CEBPG	0.823359237	7.03E-21
UVM	TF	MRPL42	ZNF484	0.82391301	6.29E-21
UVM	TF	MRPL42	ZNF24	0.824752305	5.31E-21
UVM	TF	MRPL42	ZNF572	0.824860885	5.19E-21
UVM	TF	MRPL42	MEF2A	0.826299953	3.88E-21
UVM	TF	MRPL42	AHCTF1	0.827898665	2.79E-21
UVM	TF	MRPL42	ZNF449	0.827905704	2.79E-21
UVM	TF	MRPL42	ZNF182	0.830860373	1.51E-21
UVM	TF	MRPL42	ZNF281	0.832206609	1.13E-21
UVM	TF	MRPL42	ELF1	0.833151847	9.26E-22
UVM	TF	MRPL42	GPBP1	0.833993936	7.73E-22
UVM	TF	MRPL42	ZNF136	0.834493066	6.95E-22
UVM	TF	MRPL42	ZNF468	0.834530649	6.89E-22
UVM	TF	MRPL42	SMAD5	0.835781915	5.25E-22
UVM	TF	MRPL42	ZNF181	0.837023217	4.01E-22
UVM	TF	MRPL42	THAP5	0.837495867	3.61E-22
UVM	TF	MRPL42	SP3	0.83857574	2.85E-22
UVM	TF	MRPL42	ZNF780A	0.840383043	1.90E-22
UVM	TF	MRPL42	BACH1	0.841352405	1.53E-22
UVM	TF	MRPL42	ZNF131	0.842478054	1.19E-22
UVM	TF	MRPL42	IKZF5	0.842644146	1.14E-22
UVM	TF	MRPL42	ZBTB1	0.844442422	7.56E-23
UVM	TF	MRPL42	E2F5	0.845782241	5.54E-23
UVM	TF	MRPL42	CLOCK	0.846072328	5.18E-23
UVM	TF	MRPL42	ZNF28	0.848288031	3.07E-23
UVM	TF	MRPL42	ZNF146	0.849705789	2.19E-23
UVM	TF	MRPL42	CREB1	0.850859618	1.66E-23
UVM	TF	MRPL42	ZNF267	0.851075951	1.58E-23
UVM	TF	MRPL42	ZNF675	0.855464749	5.36E-24
UVM	TF	MRPL42	TOPORS	0.856467119	4.17E-24
UVM	TF	MRPL42	ZBTB6	0.856706143	3.92E-24
UVM	TF	MRPL42	ZNF43	0.859972817	1.70E-24
UVM	TF	MRPL42	ZNF451	0.86127919	1.21E-24
UVM	TF	MRPL42	AEBP2	0.868990643	1.52E-25
UVM	TF	MRPL42	TERF1	0.875953412	2.07E-26
UVM	TF	MRPL42	CEBPZ	0.878132562	1.08E-26
UVM	TF	MRPL42	PRMT3	0.893162828	8.56E-29
UVM	TSG	MRPL42	ITGAV	0.800368592	5.20E-19
UVM	TSG	MRPL42	EGLN1	0.800832093	4.80E-19
UVM	TSG	MRPL42	CCAR1	0.80146898	4.29E-19
UVM	TSG	MRPL42	MSH2	0.803195591	3.16E-19
UVM	TSG	MRPL42	CREM	0.803973638	2.75E-19
UVM	TSG	MRPL42	ARID2	0.804188098	2.65E-19
UVM	TSG	MRPL42	PTPN2	0.80519121	2.21E-19
UVM	TSG	MRPL42	MLH3	0.806648376	1.70E-19
UVM	TSG	MRPL42	VEZT	0.806803322	1.65E-19
UVM	TSG	MRPL42	KRIT1	0.808024409	1.32E-19
UVM	TSG	MRPL42	RBBP8	0.809623099	9.87E-20
UVM	TSG	MRPL42	CUL5	0.810878082	7.82E-20
UVM	TSG	MRPL42	GORAB	0.812484131	5.80E-20
UVM	TSG	MRPL42	PAFAH1B1	0.814234351	4.17E-20
UVM	TSG	MRPL42	EZH2	0.817698925	2.14E-20
UVM	TSG	MRPL42	PPP2R5C	0.819098265	1.63E-20
UVM	TSG	MRPL42	RB1CC1	0.820049061	1.36E-20
UVM	TSG	MRPL42	PTPN12	0.823960636	6.23E-21
UVM	TSG	MRPL42	INTS6	0.82728909	3.16E-21
UVM	TSG	MRPL42	ANXA7	0.828214431	2.61E-21
UVM	TSG	MRPL42	BMPR2	0.82915217	2.15E-21
UVM	TSG	MRPL42	GGNBP2	0.831491191	1.32E-21
UVM	TSG	MRPL42	WDR11	0.831988494	1.19E-21
UVM	TSG	MRPL42	CHUK	0.839647852	2.24E-22
UVM	TSG	MRPL42	PDS5B	0.841210335	1.58E-22
UVM	TSG	MRPL42	PRKAA1	0.842343564	1.22E-22
UVM	TSG	MRPL42	NAPEPLD	0.842634076	1.14E-22
UVM	TSG	MRPL42	CSNK1A1	0.845393873	6.06E-23
UVM	TSG	MRPL42	RINT1	0.849612078	2.24E-23
UVM	TSG	MRPL42	CUL2	0.850772528	1.70E-23
UVM	TSG	MRPL42	SUZ12	0.850936891	1.63E-23
UVM	TSG	MRPL42	ATM	0.850967712	1.62E-23
UVM	TSG	MRPL42	LIN9	0.85281204	1.03E-23
UVM	TSG	MRPL42	TOPORS	0.856467119	4.17E-24
UVM	TSG	MRPL42	GTPBP4	0.860708276	1.41E-24
UVM	TSG	MRPL42	CDC73	0.860856668	1.35E-24
UVM	TSG	MRPL42	BMPR1A	0.86319147	7.33E-25
UVM	TSG	MRPL42	SMCHD1	0.868663509	1.66E-25
UVM	TSG	MRPL42	NBN	0.878678175	9.18E-27

Top

Protein structure

Protein 3D structure
Visit iCn3D.

Top

Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
BRCA	MRPL42	MRPL32	-3.7979134181794	0.000134327661287861
LUAD	MRPL42	MRPS18A	-1.54123864042049	0.000452706327224566
LUAD	MRPL42	MRPL32	-2.1966239418264	0.00121089428940613
KIRC	MRPL42	MRPS18B	-1.08999348010674	0.00208385211535325
STAD	MRPL42	MRPS16	-1.64208084987431	0.00239070039242506
LIHC	MRPL42	MRPS18C	-1.25336042046698	0.00251545393492315
COAD	MRPL42	MRPS18C	-3.48505830240365	0.00322914123535157
HNSC	MRPL42	MRPS16	-2.01564621821803	0.00518989327406416
CHOL	MRPL42	MRPS18B	-1.34341961473083	0.0078125
BLCA	MRPL42	MRPS36	-1.37783544110041	0.00823211669921875
KICH	MRPL42	MRPS2	1.26543989555015	0.0114533305168152
LUAD	MRPL42	MRPS36	-2.6018646350856	0.0160454872238539
PRAD	MRPL42	MRPS18A	-1.89251195553289	0.0168224419088856
BLCA	MRPL42	MRPS18B	-2.79316203705083	0.0180816650390625
KIRP	MRPL42	MRPS36	-1.17144906491842	0.0194480954669416
LUAD	MRPL42	MRPS18B	-2.59132604284176	0.0228310323601027
ESCA	MRPL42	MRPS2	-3.20556788084675	0.0244140625
THCA	MRPL42	MRPS11	-3.10694728540962	0.0252226935182201
STAD	MRPL42	MRPS18B	-2.18783845061495	0.0341199110262096
KIRC	MRPL42	MRPL32	-2.79664327578899	0.0376051795400881
BLCA	MRPL42	MRPS11	-2.30276998968219	0.040130615234375
LUSC	MRPL42	MRPS18A	-4.26181803018125	1.79996309233889e-05
LUSC	MRPL42	MRPS2	-2.70930846488508	1.92864354932136e-09
LIHC	MRPL42	MRPL32	-1.20074144698753	2.24402029682138e-06
BRCA	MRPL42	MRPS11	-1.24304977976804	2.31302509538916e-07
COAD	MRPL42	MRPS36	-1.55049755510511	2.62260437011719e-06
PRAD	MRPL42	MRPL37	-2.21074342735295	3.65283830814974e-07
LUAD	MRPL42	MRPL37	-2.86549200993971	3.76287422734829e-10
LIHC	MRPL42	MRPS2	-1.14771055358828	4.2584580238307e-05
LUSC	MRPL42	MRPS11	-2.9004097541444	5.43966600483641e-07
HNSC	MRPL42	MRPS18A	-2.4520120168475	5.97184352955084e-05
BRCA	MRPL42	MRPL37	-3.79079551418026	9.33185484212232e-10

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPL42

IKBKAP, EEF1A1, MRPL40, MRPL32, MRPL13, MRPS9, MRPL23, MRPL3, MRPS26, MRPL41, MRPL12, MRPL37, MRPL44, MRPS35, MRPS28, ILF3, HNRNPR, HNRNPU, CYB5B, ICT1, DDX28, FUBP1, HNRNPC, ATP5F1, DLD, rev, MRPL43, RPL13, RPL6, MRPL4, MRPL39, CASQ2, MRPS30, MRPL47, MRPL50, MRPL9, MRPL1, Cdc37, MRPL10, MRPL51, MRPL21, GATC, MRPL45, GADD45GIP1, MRPL11, MRPL38, MRPL27, MRPL30, MRPL49, MRPL28, MRPL55, MRPL24, MRPL20, MRPL35, SIRT3, MRPL22, MRPL57, MRPL2, MALSU1, MRPL17, RNMTL1, MRPL33, MRPL16, MRPS18A, MRPL15, MRPL19, MRPL48, NGRN, MRPL34, MRPL18, MRPL46, ACAA1, HNRNPL, KCTD10, MED23, MED24, MRPL36, MRPL42, MRPS5, PGK1, ROMO1, SRSF7, MRM1, HSPD1, PDK1, TRMT61B, APEX1, RASA1, GRSF1, ACAD9, AUH, C12orf65, C1QBP, C21orf33, C6orf203, CHCHD1, CS, FASTKD2, FASTKD3, FASTKD5, GFM1, GFM2, HINT2, LRPPRC, CCDC109B, MDH2, METTL15, METTL17, MRPS12, MRRF, MTERF3, MTFMT, MTIF2, MTIF3, MTRF1, MTRF1L, PMPCA, PMPCB, RPUSD4, SLIRP, SSBP1, TACO1, TBRG4, TFAM, TMEM70, TRUB2, TSFM, TUFM, VWA8, EXD2, DDX58, AARS2, COX8A, PDHA1, TRAP1, IDE, IGF2BP3, RPL27A, YBX1, RBMS2, MRPL53, MRPL52, H1FNT, SRSF3, GNL3, YBX2, RPL37, FAM120A, S100A2, HGS, NAA15, NOMO1, PTPN11, RPL19, NSUN2, MRPL54, MCMBP, SF3A1, DIS3, AP3B1, LIN28A, TTC1, EIF2AK2, RBM25, PTCD1, LCN1, RPL17, EDC3, TRIP10, CSE1L, PRR3, TOMM40, IDH2, USP19, SUPT5H, NCAPG, PPP1R8, DBNL, PDLIM1, GTF2F1, GTF2I, ARHGAP18, SMEK1, RBMS3, RPL35, SNX1, SNX2, OXSR1, STK26, SNX27, FAM129B, GEMIN5, SYMPK, NEIL1, NMD3, VRK1, ZNF574, IST1, PNPT1, NCAPD2, GNL1, SYNJ2BP, OSBPL8, PTRH2, ADSS, RAP1BL, PGRMC2, ABT1, ALCAM, PRPF40A, KLC2, RBM47, GLS, MSI1, CCDC6, RBM12, FAM49B, SFXN1, WDHD1, FAHD1, OXA1L, PAPOLA, PBK, HIST1H1T, PDS5A, RBM26, UBA6, ARFIP1, HDLBP, PPP1R12A, NAA10, OGFOD1, CLUH, SRRT, PUS1,

Top

Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPL42	HNSC	chr12	93873224	93873224	G	C	Silent	p.V65V	2
MRPL42	HNSC	chr12	93873187	93873187	C	A	Missense_Mutation	p.S53Y	2
MRPL42	SARC	chr12	93894747	93894748	-	A	RNA	NULL	2
MRPL42	SKCM	chr12	93881291	93881291	C	T	Missense_Mutation	p.P80S	2
MRPL42	UCEC	chr12	93863065	93863065	G	A	Missense_Mutation	p.A2T	2
MRPL42	OV	chr12	93881315	93881315	C	G	Missense_Mutation	p.H88D	1
MRPL42	HNSC	chr12	93881417	93881417	C	A	Missense_Mutation		1
MRPL42	OV	chr12	93881354	93881354	G	T	Nonsense_Mutation	p.E101*	1
MRPL42	HNSC	chr12	93873187	93873187	C	A	Missense_Mutation		1
MRPL42	READ	chr12	93894974	93894974	C	T	Silent	p.L136L	1
MRPL42	SARC	chr12	93881334	93881334	C	-	Frame_Shift_Del		1
MRPL42	SARC	chr12	93881326	93881326	G	T	Silent		1
MRPL42	LGG	chr12	93881384	93881384	C	A	Missense_Mutation	p.Q111K	1
MRPL42	LUAD	chr12	93863091	93863091	G	T	Missense_Mutation	p.M10I	1
MRPL42	SARC	chr12	93894748	93894748	A	-	RNA	NULL	1
MRPL42	LUAD	chr12	93870766	93870766	A	T	Missense_Mutation	p.Y36F	1
MRPL42	LUAD	chr12	93881322	93881322	A	T	Missense_Mutation	p.Q90L	1
MRPL42	SKCM	chr12	93894980	93894980	C	T	Missense_Mutation	p.P138S	1
MRPL42	LUAD	chr12	93881410	93881410	T	C	Silent	p.T119T	1
MRPL42	UCEC	chr12	93873187	93873187	C	G	Missense_Mutation	p.S53C	1
MRPL42	COAD	chr12	93873236	93873236	T	C	Silent	p.Y69Y	1
MRPL42	LUSC	chr12	93863109	93863109	G	C	Missense_Mutation	p.E10Q	1
MRPL42	HNSC	chr12	93873224	93873224	G	C	Silent		1

Copy number variation (CNV) of MRPL42
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPL42
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
99938	OV	TCGA-61-1918-01A	CRADD	chr12	94072848	+	MRPL42	chr12	93894952	+
99938	STAD	TCGA-BR-4357	CRADD	chr12	94072848	+	MRPL42	chr12	93894951	+
99938	N/A	FI185375	GOLGA1	chr9	127702734	+	MRPL42	chr12	93896662	-
99938	N/A	BU742854	METTL2B	chr7	128144782	+	MRPL42	chr12	93896901	-
97219	STAD	TCGA-BR-A4J5-01A	MRPL42	chr12	93881436	+	CNOT2	chr12	70735887	+
100814	SARC	TCGA-DX-A7EI-01A	MRPL42	chr12	93881436	+	FGD6	chr12	95475332	-
55051	N/A	FN126893	MRPL42	chr12	93870748	-	GJD4	chr10	35895472	+
94008	SARC	TCGA-DX-A3M1-01A	MRPL42	chr12	93861330	+	NTN4	chr12	96131922	-
55051	BLCA	TCGA-CF-A7I0-01A	MRPL42	chr12	93881436	+	POLR3B	chr12	106903198	+
55051	N/A	AA603490	MRPL42	chr12	93889865	+	RP11-625L16.1	chr12	24896737	-
98970	N/A	AA643790	MRPL42	chr12	93864098	+	RPL35	chr9	127620162	+
101313	PRAD	TCGA-HC-8266-01A	MRPL42	chr12	93870793	-	ZMIZ1	chr10	81036938	+
99938	READ	TCGA-F5-6863-01A	NUDT4	chr12	93792631	+	MRPL42	chr12	93894952	+
99938	PRAD	TCGA-YL-A9WY-01A	PIK3R1	chr5	67522837	+	MRPL42	chr12	93862965	+
99938	SARC	TCGA-DX-A23R	PLEKHG7	chr12	93135368	+	MRPL42	chr12	93894951	+
99938	SARC	TCGA-DX-A23R-01A	PLEKHG7	chr12	93135368	+	MRPL42	chr12	93894952	+
99942	PRAD	TCGA-EJ-7315-01A	YBX3	chr12	10875448	-	MRPL42	chr12	93894951	+
99942	PRAD	TCGA-EJ-7315-01A	YBX3	chr12	10875449	-	MRPL42	chr12	93894952	+

Top

Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

Top

Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
TGCT	MRPL42	0.00172604007941756	0.047
SARC	MRPL42	0.0125394404244077	0.33
HNSC	MRPL42	0.0174590615561644	0.44
THCA	MRPL42	0.0198889653081902	0.48
LUAD	MRPL42	6.68442415845824e-06	0.00019

Top

Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	MRPL42	0.0143417089309181	0.44
LUSC	MRPL42	0.046501319774669	1
KIRC	MRPL42	0.00383414863375554	0.13
GBM	MRPL42	0.0448360030373978	1
OV	MRPL42	0.0130454894368407	0.42

Top

Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source