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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPL2 (NCBI Gene ID:51069)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPL2
	Gene ID: 51069
	Gene Symbol	MRPL2
	Gene ID	51069
	Gene Name	mitochondrial ribosomal protein L2
	Synonyms	CGI-22\|MRP-L14\|RPML14
	Cytomap	6p21.1
	Type of Gene	protein-coding
	Description	39S ribosomal protein L2, mitochondrialL2mtMRP-L2mitochondrial large ribosomal subunit protein uL2m
	Modification date	20200313
	UniProtAcc	Q5T653

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0032543	Mitochondrial translation
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
MRPL2	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'MRPL2[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPL2	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000388752	43023282	43023356	Frame-shift
ENST00000388752	43023634	43023745	In-frame
ENST00000388752	43024044	43024183	Frame-shift

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000388752	43023634	43023745	1605	946	1056	305	173	210

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q5T653	173	210	61	305	Chain	ID=PRO_0000261640;Note=39S ribosomal protein L2%2C mitochondrial
Q5T653	173	210	181	183	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:5OOM
Q5T653	173	210	184	186	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:5OOM
Q5T653	173	210	192	196	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:5OOM
Q5T653	173	210	200	202	Turn	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:5OOL
Q5T653	173	210	204	207	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:5OOL

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
CHOL	MRPL2	-1.49926301466752	0.00390625
BLCA	MRPL2	-3.29210657477178	0.0445594787597656
LUAD	MRPL2	-1.26727646741024	1.07341296213058e-06
LUSC	MRPL2	-2.66710222706783	7.24218086307245e-08

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
KIRC	MRPL2	-0.029506333	0.006482864

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPL2 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	MRPL2	SLC25A11	0.850141204	1.48E-13
CHOL	IUPHAR	MRPL2	SLC25A11	0.850141204	1.48E-13
DLBC	Cell metabolism gene	MRPL2	PSMC5	0.807403065	4.13E-12
DLBC	Cell metabolism gene	MRPL2	MIF	0.81278651	2.29E-12
DLBC	Cell metabolism gene	MRPL2	DTYMK	0.816421399	1.52E-12
DLBC	Cell metabolism gene	MRPL2	POLR2L	0.816635573	1.48E-12
DLBC	Cell metabolism gene	MRPL2	SNRPD3	0.822816315	7.24E-13
DLBC	Cell metabolism gene	MRPL2	PSMD13	0.822838791	7.22E-13
DLBC	Cell metabolism gene	MRPL2	IDH3B	0.827802334	3.97E-13
DLBC	Cell metabolism gene	MRPL2	TIMM10	0.829266276	3.32E-13
DLBC	Cell metabolism gene	MRPL2	PSMB7	0.83060187	2.81E-13
DLBC	Cell metabolism gene	MRPL2	TIMM8B	0.830664833	2.79E-13
DLBC	Cell metabolism gene	MRPL2	PTDSS2	0.831198515	2.61E-13
DLBC	Cell metabolism gene	MRPL2	TIMM8A	0.833401223	1.98E-13
DLBC	Cell metabolism gene	MRPL2	SNRPD2	0.834383248	1.75E-13
DLBC	Cell metabolism gene	MRPL2	EXOSC5	0.837906664	1.11E-13
DLBC	Cell metabolism gene	MRPL2	TOMM22	0.839946459	8.49E-14
DLBC	Cell metabolism gene	MRPL2	TIMM9	0.844289852	4.74E-14
DLBC	Cell metabolism gene	MRPL2	SNRPE	0.844572675	4.56E-14
DLBC	Cell metabolism gene	MRPL2	PSMC3	0.847025263	3.25E-14
DLBC	Cell metabolism gene	MRPL2	PMPCA	0.850702139	1.94E-14
DLBC	Cell metabolism gene	MRPL2	ADSL	0.851173279	1.81E-14
DLBC	Cell metabolism gene	MRPL2	ITPA	0.852802323	1.43E-14
DLBC	Cell metabolism gene	MRPL2	NME2	0.853660169	1.26E-14
DLBC	Cell metabolism gene	MRPL2	EXOSC4	0.85575135	9.29E-15
DLBC	Cell metabolism gene	MRPL2	PSMB3	0.862103998	3.54E-15
DLBC	Cell metabolism gene	MRPL2	POLR2I	0.870013971	9.95E-16
DLBC	Cell metabolism gene	MRPL2	ATP5G1	0.870511532	9.16E-16
DLBC	Cell metabolism gene	MRPL2	TIMM50	0.876823778	3.12E-16
DLBC	Cell metabolism gene	MRPL2	PFDN6	0.8801211	1.73E-16
DLBC	Cell metabolism gene	MRPL2	POLR2F	0.882084478	1.21E-16
DLBC	Cell metabolism gene	MRPL2	TIMM13	0.887739547	4.16E-17
DLBC	CGC	MRPL2	HRAS	0.801630903	7.61E-12
DLBC	CGC	MRPL2	U2AF1	0.838995784	9.62E-14
DLBC	Epifactor	MRPL2	RUVBL2	0.820222754	9.81E-13
DLBC	Epifactor	MRPL2	EXOSC5	0.837906664	1.11E-13
DLBC	Epifactor	MRPL2	FBL	0.842747048	5.84E-14
DLBC	Epifactor	MRPL2	EXOSC4	0.85575135	9.29E-15
DLBC	IUPHAR	MRPL2	UCHL3	0.800312913	8.73E-12
DLBC	IUPHAR	MRPL2	HRAS	0.801630903	7.61E-12
DLBC	IUPHAR	MRPL2	MFSD2B	0.853413911	1.31E-14
DLBC	TF	MRPL2	THAP4	0.838782273	9.90E-14
DLBC	TF	MRPL2	NME2	0.853660169	1.26E-14
DLBC	TSG	MRPL2	PARK7	0.80148449	7.73E-12
DLBC	TSG	MRPL2	PHB	0.885178832	6.80E-17
DLBC	TSG	MRPL2	GADD45GIP1	0.886047709	5.76E-17
LAML	Cell metabolism gene	MRPL2	AAAS	0.814522021	2.73E-42
LAML	Cell metabolism gene	MRPL2	MIF	0.81510034	2.14E-42
LAML	Cell metabolism gene	MRPL2	POLR2I	0.826975509	1.27E-44
LAML	TSG	MRPL2	GADD45GIP1	0.80640262	7.32E-41
LUSC	Cell metabolism gene	MRPL2	POLR1C	0.8136015	7.17E-132
PCPG	Cell metabolism gene	MRPL2	PFDN6	0.808202788	2.08E-44
PRAD	Cell metabolism gene	MRPL2	PSMB1	0.859030121	1.75E-161
PRAD	IUPHAR	MRPL2	PSMB1	0.859030121	1.75E-161
READ	Cell metabolism gene	MRPL2	POLR1C	0.809489333	1.46E-25
SKCM	IUPHAR	MRPL2	CSNK2B	0.812131102	1.65E-112
THCA	Cell metabolism gene	MRPL2	EXOSC4	0.803148096	2.61E-130
THCA	Cell metabolism gene	MRPL2	GAMT	0.803621672	1.42E-130
THCA	Cell metabolism gene	MRPL2	UROD	0.806219566	4.79E-132
THCA	Cell metabolism gene	MRPL2	PSMB3	0.807491726	8.94E-133
THCA	Cell metabolism gene	MRPL2	TOMM40	0.808620646	1.99E-133
THCA	Cell metabolism gene	MRPL2	TIMM50	0.810320058	2.05E-134
THCA	Cell metabolism gene	MRPL2	TIMM8B	0.812369069	1.28E-135
THCA	Cell metabolism gene	MRPL2	PSMB6	0.813162646	4.31E-136
THCA	Cell metabolism gene	MRPL2	APRT	0.818470511	2.67E-139
THCA	Cell metabolism gene	MRPL2	POLR2J	0.825164255	1.69E-143
THCA	Cell metabolism gene	MRPL2	IDH3G	0.826618756	1.96E-144
THCA	Cell metabolism gene	MRPL2	DPM3	0.850757924	2.23E-161
THCA	Cell metabolism gene	MRPL2	TIMM13	0.850843357	1.91E-161
THCA	Cell metabolism gene	MRPL2	MTX1	0.851204763	1.01E-161
THCA	Cell metabolism gene	MRPL2	POLR2I	0.85605054	1.69E-165
THCA	CGC	MRPL2	ASPSCR1	0.82167994	2.72E-141
THCA	CGC	MRPL2	COX6C	0.847354972	8.16E-159
THCA	Epifactor	MRPL2	EXOSC4	0.803148096	2.61E-130
THCA	Epifactor	MRPL2	CCDC101	0.806091276	5.66E-132
THCA	Epifactor	MRPL2	BRMS1	0.819969373	3.17E-140
THCA	Epifactor	MRPL2	RUVBL2	0.845313436	2.63E-157
THCA	Epifactor	MRPL2	ZNHIT1	0.849234649	3.19E-160
THCA	IUPHAR	MRPL2	PSMB6	0.813162646	4.31E-136
THCA	Kinase	MRPL2	FASTK	0.808317859	2.98E-133
THCA	TF	MRPL2	THAP3	0.805906596	7.22E-132
THCA	TF	MRPL2	ZNF688	0.820013971	2.98E-140
THCA	TSG	MRPL2	NPRL2	0.809676369	4.86E-134
THCA	TSG	MRPL2	PARK7	0.816433292	4.68E-138
THCA	TSG	MRPL2	BRMS1	0.819969373	3.17E-140
THCA	TSG	MRPL2	GADD45GIP1	0.836670709	3.74E-151
THYM	Cell metabolism gene	MRPL2	GUK1	0.800258746	2.02E-28
THYM	Cell metabolism gene	MRPL2	PSMC1	0.80162881	1.39E-28
THYM	Cell metabolism gene	MRPL2	POLR2F	0.802280398	1.17E-28
THYM	Cell metabolism gene	MRPL2	SLC27A5	0.804338544	6.66E-29
THYM	Cell metabolism gene	MRPL2	PSMD9	0.804984883	5.58E-29
THYM	Cell metabolism gene	MRPL2	LSM4	0.80860859	2.03E-29
THYM	Cell metabolism gene	MRPL2	PFDN5	0.808912721	1.86E-29
THYM	Cell metabolism gene	MRPL2	PSMA4	0.808921934	1.86E-29
THYM	Cell metabolism gene	MRPL2	PSMB10	0.812427776	6.85E-30
THYM	Cell metabolism gene	MRPL2	MVD	0.813201639	5.48E-30
THYM	Cell metabolism gene	MRPL2	TIMM8B	0.813313676	5.30E-30
THYM	Cell metabolism gene	MRPL2	DPM2	0.817287371	1.66E-30
THYM	Cell metabolism gene	MRPL2	ACOT8	0.819796735	7.82E-31
THYM	Cell metabolism gene	MRPL2	SLC25A11	0.820515836	6.29E-31
THYM	Cell metabolism gene	MRPL2	ITPA	0.823025731	2.93E-31
THYM	Cell metabolism gene	MRPL2	IDH3G	0.824839802	1.67E-31
THYM	Cell metabolism gene	MRPL2	TIMM50	0.830220729	3.05E-32
THYM	Cell metabolism gene	MRPL2	POLR2I	0.835803631	4.89E-33
THYM	Cell metabolism gene	MRPL2	FAU	0.836304371	4.13E-33
THYM	Cell metabolism gene	MRPL2	APRT	0.83812552	2.24E-33
THYM	Cell metabolism gene	MRPL2	PSMB3	0.838147506	2.22E-33
THYM	Cell metabolism gene	MRPL2	PSMD13	0.846696124	1.12E-34
THYM	Cell metabolism gene	MRPL2	PFDN6	0.847267346	9.11E-35
THYM	Cell metabolism gene	MRPL2	PSMB7	0.848319717	6.22E-35
THYM	Cell metabolism gene	MRPL2	PSMB6	0.8541163	7.20E-36
THYM	Cell metabolism gene	MRPL2	TIMM13	0.854847381	5.45E-36
THYM	Cell metabolism gene	MRPL2	PGLS	0.859625973	8.48E-37
THYM	Cell metabolism gene	MRPL2	SNRPD2	0.860048553	7.17E-37
THYM	Cell metabolism gene	MRPL2	UROD	0.87324925	2.83E-39
THYM	Cell metabolism gene	MRPL2	PSMC3	0.873555959	2.47E-39
THYM	Cell metabolism gene	MRPL2	LSM2	0.894072117	1.13E-43
THYM	Cell metabolism gene	MRPL2	PSMB1	0.903301301	6.32E-46
THYM	CGC	MRPL2	RBM10	0.800983181	1.66E-28
THYM	CGC	MRPL2	U2AF1	0.804882795	5.73E-29
THYM	CGC	MRPL2	TFPT	0.875182091	1.20E-39
THYM	CGC	MRPL2	MAP2K2	0.878456601	2.68E-40
THYM	Epifactor	MRPL2	BRMS1	0.805552943	4.77E-29
THYM	Epifactor	MRPL2	INO80E	0.810008061	1.37E-29
THYM	Epifactor	MRPL2	TRIM28	0.815559845	2.76E-30
THYM	Epifactor	MRPL2	SIRT6	0.821793125	4.27E-31
THYM	Epifactor	MRPL2	FBL	0.831523586	2.00E-32
THYM	Epifactor	MRPL2	TAF10	0.833091331	1.20E-32
THYM	Epifactor	MRPL2	ZNHIT1	0.835222324	5.93E-33
THYM	Epifactor	MRPL2	PPP4C	0.840181677	1.11E-33
THYM	Epifactor	MRPL2	PAF1	0.852326904	1.41E-35
THYM	Epifactor	MRPL2	C17orf49	0.852706725	1.23E-35
THYM	Epifactor	MRPL2	CCDC101	0.861558864	3.92E-37
THYM	Epifactor	MRPL2	DMAP1	0.864627164	1.12E-37
THYM	Epifactor	MRPL2	MBD3	0.866529351	5.10E-38
THYM	Epifactor	MRPL2	TFPT	0.875182091	1.20E-39
THYM	Epifactor	MRPL2	RUVBL2	0.876634571	6.19E-40
THYM	Epifactor	MRPL2	PRPF31	0.886332697	6.14E-42
THYM	IUPHAR	MRPL2	SLC27A5	0.804338544	6.66E-29
THYM	IUPHAR	MRPL2	MVD	0.813201639	5.48E-30
THYM	IUPHAR	MRPL2	TRIM28	0.815559845	2.76E-30
THYM	IUPHAR	MRPL2	SLC25A11	0.820515836	6.29E-31
THYM	IUPHAR	MRPL2	SIRT6	0.821793125	4.27E-31
THYM	IUPHAR	MRPL2	PSMB6	0.8541163	7.20E-36
THYM	IUPHAR	MRPL2	MMP24	0.864393151	1.24E-37
THYM	IUPHAR	MRPL2	MAP2K2	0.878456601	2.68E-40
THYM	IUPHAR	MRPL2	CSNK2B	0.881981535	5.12E-41
THYM	IUPHAR	MRPL2	PSMB1	0.903301301	6.32E-46
THYM	Kinase	MRPL2	TRIM28	0.815559845	2.76E-30
THYM	Kinase	MRPL2	MAP2K2	0.878456601	2.68E-40
THYM	TF	MRPL2	SNAPC2	0.803183924	9.14E-29
THYM	TF	MRPL2	AKAP8L	0.809393298	1.63E-29
THYM	TF	MRPL2	DNTTIP1	0.812221527	7.27E-30
THYM	TF	MRPL2	ZNF668	0.812843399	6.08E-30
THYM	TF	MRPL2	ZNF444	0.820012327	7.33E-31
THYM	TF	MRPL2	ZNF653	0.826579679	9.70E-32
THYM	TF	MRPL2	ZNF787	0.829362974	4.01E-32
THYM	TF	MRPL2	DRAP1	0.846505047	1.20E-34
THYM	TF	MRPL2	ZNF32	0.847154102	9.50E-35
THYM	TF	MRPL2	THYN1	0.847319984	8.94E-35
THYM	TF	MRPL2	MBD3	0.866529351	5.10E-38
THYM	TF	MRPL2	THAP3	0.868289698	2.43E-38
THYM	TF	MRPL2	ZNF428	0.879075783	2.01E-40
THYM	TSG	MRPL2	BRMS1	0.805552943	4.77E-29
THYM	TSG	MRPL2	ZNF668	0.812843399	6.08E-30
THYM	TSG	MRPL2	MAD1L1	0.814446577	3.82E-30
THYM	TSG	MRPL2	PFN1	0.819940425	7.49E-31
THYM	TSG	MRPL2	SIRT6	0.821793125	4.27E-31
THYM	TSG	MRPL2	PARK7	0.823086266	2.87E-31
THYM	TSG	MRPL2	GNB2L1	0.826194134	1.09E-31
THYM	TSG	MRPL2	GADD45GIP1	0.835447608	5.51E-33
THYM	TSG	MRPL2	GLTSCR2	0.838925326	1.70E-33
THYM	TSG	MRPL2	TSSC4	0.845220517	1.90E-34
THYM	TSG	MRPL2	HTRA2	0.849512387	4.02E-35
UCEC	Cell metabolism gene	MRPL2	POLR1C	0.820160793	3.79E-50
UCEC	IUPHAR	MRPL2	CSNK2B	0.825199711	2.94E-51
UCS	Cell metabolism gene	MRPL2	GUK1	0.800258746	2.02E-28
UCS	Cell metabolism gene	MRPL2	PSMC1	0.80162881	1.39E-28
UCS	Cell metabolism gene	MRPL2	POLR2F	0.802280398	1.17E-28
UCS	Cell metabolism gene	MRPL2	SLC27A5	0.804338544	6.66E-29
UCS	Cell metabolism gene	MRPL2	PSMD9	0.804984883	5.58E-29
UCS	Cell metabolism gene	MRPL2	LSM4	0.80860859	2.03E-29
UCS	Cell metabolism gene	MRPL2	PFDN5	0.808912721	1.86E-29
UCS	Cell metabolism gene	MRPL2	PSMA4	0.808921934	1.86E-29
UCS	Cell metabolism gene	MRPL2	PSMB10	0.812427776	6.85E-30
UCS	Cell metabolism gene	MRPL2	MVD	0.813201639	5.48E-30
UCS	Cell metabolism gene	MRPL2	TIMM8B	0.813313676	5.30E-30
UCS	Cell metabolism gene	MRPL2	DPM2	0.817287371	1.66E-30
UCS	Cell metabolism gene	MRPL2	ACOT8	0.819796735	7.82E-31
UCS	Cell metabolism gene	MRPL2	SLC25A11	0.820515836	6.29E-31
UCS	Cell metabolism gene	MRPL2	ITPA	0.823025731	2.93E-31
UCS	Cell metabolism gene	MRPL2	IDH3G	0.824839802	1.67E-31
UCS	Cell metabolism gene	MRPL2	TIMM50	0.830220729	3.05E-32
UCS	Cell metabolism gene	MRPL2	POLR2I	0.835803631	4.89E-33
UCS	Cell metabolism gene	MRPL2	FAU	0.836304371	4.13E-33
UCS	Cell metabolism gene	MRPL2	APRT	0.83812552	2.24E-33
UCS	Cell metabolism gene	MRPL2	PSMB3	0.838147506	2.22E-33
UCS	Cell metabolism gene	MRPL2	PSMD13	0.846696124	1.12E-34
UCS	Cell metabolism gene	MRPL2	PFDN6	0.847267346	9.11E-35
UCS	Cell metabolism gene	MRPL2	PSMB7	0.848319717	6.22E-35
UCS	Cell metabolism gene	MRPL2	PSMB6	0.8541163	7.20E-36
UCS	Cell metabolism gene	MRPL2	TIMM13	0.854847381	5.45E-36
UCS	Cell metabolism gene	MRPL2	PGLS	0.859625973	8.48E-37
UCS	Cell metabolism gene	MRPL2	SNRPD2	0.860048553	7.17E-37
UCS	Cell metabolism gene	MRPL2	UROD	0.87324925	2.83E-39
UCS	Cell metabolism gene	MRPL2	PSMC3	0.873555959	2.47E-39
UCS	Cell metabolism gene	MRPL2	LSM2	0.894072117	1.13E-43
UCS	Cell metabolism gene	MRPL2	PSMB1	0.903301301	6.32E-46
UCS	CGC	MRPL2	RBM10	0.800983181	1.66E-28
UCS	CGC	MRPL2	U2AF1	0.804882795	5.73E-29
UCS	CGC	MRPL2	TFPT	0.875182091	1.20E-39
UCS	CGC	MRPL2	MAP2K2	0.878456601	2.68E-40
UCS	Epifactor	MRPL2	BRMS1	0.805552943	4.77E-29
UCS	Epifactor	MRPL2	INO80E	0.810008061	1.37E-29
UCS	Epifactor	MRPL2	TRIM28	0.815559845	2.76E-30
UCS	Epifactor	MRPL2	SIRT6	0.821793125	4.27E-31
UCS	Epifactor	MRPL2	FBL	0.831523586	2.00E-32
UCS	Epifactor	MRPL2	TAF10	0.833091331	1.20E-32
UCS	Epifactor	MRPL2	ZNHIT1	0.835222324	5.93E-33
UCS	Epifactor	MRPL2	PPP4C	0.840181677	1.11E-33
UCS	Epifactor	MRPL2	PAF1	0.852326904	1.41E-35
UCS	Epifactor	MRPL2	C17orf49	0.852706725	1.23E-35
UCS	Epifactor	MRPL2	CCDC101	0.861558864	3.92E-37
UCS	Epifactor	MRPL2	DMAP1	0.864627164	1.12E-37
UCS	Epifactor	MRPL2	MBD3	0.866529351	5.10E-38
UCS	Epifactor	MRPL2	TFPT	0.875182091	1.20E-39
UCS	Epifactor	MRPL2	RUVBL2	0.876634571	6.19E-40
UCS	Epifactor	MRPL2	PRPF31	0.886332697	6.14E-42
UCS	IUPHAR	MRPL2	SLC27A5	0.804338544	6.66E-29
UCS	IUPHAR	MRPL2	MVD	0.813201639	5.48E-30
UCS	IUPHAR	MRPL2	TRIM28	0.815559845	2.76E-30
UCS	IUPHAR	MRPL2	SLC25A11	0.820515836	6.29E-31
UCS	IUPHAR	MRPL2	SIRT6	0.821793125	4.27E-31
UCS	IUPHAR	MRPL2	PSMB6	0.8541163	7.20E-36
UCS	IUPHAR	MRPL2	MMP24	0.864393151	1.24E-37
UCS	IUPHAR	MRPL2	MAP2K2	0.878456601	2.68E-40
UCS	IUPHAR	MRPL2	CSNK2B	0.881981535	5.12E-41
UCS	IUPHAR	MRPL2	PSMB1	0.903301301	6.32E-46
UCS	Kinase	MRPL2	TRIM28	0.815559845	2.76E-30
UCS	Kinase	MRPL2	MAP2K2	0.878456601	2.68E-40
UCS	TF	MRPL2	SNAPC2	0.803183924	9.14E-29
UCS	TF	MRPL2	AKAP8L	0.809393298	1.63E-29
UCS	TF	MRPL2	DNTTIP1	0.812221527	7.27E-30
UCS	TF	MRPL2	ZNF668	0.812843399	6.08E-30
UCS	TF	MRPL2	ZNF444	0.820012327	7.33E-31
UCS	TF	MRPL2	ZNF653	0.826579679	9.70E-32
UCS	TF	MRPL2	ZNF787	0.829362974	4.01E-32
UCS	TF	MRPL2	DRAP1	0.846505047	1.20E-34
UCS	TF	MRPL2	ZNF32	0.847154102	9.50E-35
UCS	TF	MRPL2	THYN1	0.847319984	8.94E-35
UCS	TF	MRPL2	MBD3	0.866529351	5.10E-38
UCS	TF	MRPL2	THAP3	0.868289698	2.43E-38
UCS	TF	MRPL2	ZNF428	0.879075783	2.01E-40
UCS	TSG	MRPL2	BRMS1	0.805552943	4.77E-29
UCS	TSG	MRPL2	ZNF668	0.812843399	6.08E-30
UCS	TSG	MRPL2	MAD1L1	0.814446577	3.82E-30
UCS	TSG	MRPL2	PFN1	0.819940425	7.49E-31
UCS	TSG	MRPL2	SIRT6	0.821793125	4.27E-31
UCS	TSG	MRPL2	PARK7	0.823086266	2.87E-31
UCS	TSG	MRPL2	GNB2L1	0.826194134	1.09E-31
UCS	TSG	MRPL2	GADD45GIP1	0.835447608	5.51E-33
UCS	TSG	MRPL2	GLTSCR2	0.838925326	1.70E-33
UCS	TSG	MRPL2	TSSC4	0.845220517	1.90E-34
UCS	TSG	MRPL2	HTRA2	0.849512387	4.02E-35
UVM	Cell metabolism gene	MRPL2	PPP2R5D	0.833784882	8.09E-22
UVM	CGC	MRPL2	HMGA1	0.814563333	3.91E-20
UVM	Epifactor	MRPL2	FOXP4	0.800628751	4.97E-19
UVM	Epifactor	MRPL2	RNF40	0.811192647	7.38E-20
UVM	Epifactor	MRPL2	PELP1	0.812748625	5.51E-20
UVM	IUPHAR	MRPL2	TUBB	0.833764581	8.12E-22
UVM	IUPHAR	MRPL2	CSNK2B	0.855937674	4.76E-24
UVM	TF	MRPL2	FOXP4	0.800628751	4.97E-19
UVM	TF	MRPL2	HMGA1	0.814563333	3.91E-20

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
BRCA	MRPL2	MRPL32	-3.7979134181794	0.000134327661287861
KIRC	MRPL2	MRPL11	-1.04966837625557	0.000354478033746394
LIHC	MRPL2	MRPL13	1.54402472107614	0.000655351190157038
KIRC	MRPL2	MRPL46	-7.36081421944909	0.0011460554764592
LUAD	MRPL2	MRPL32	-2.1966239418264	0.00121089428940613
KIRP	MRPL2	MRPL46	-7.17671685013906	0.00123529229313135
ESCA	MRPL2	MRPL47	-2.26373711796715	0.001953125
CHOL	MRPL2	MRPL46	-2.73791743817321	0.00390625
ESCA	MRPL2	MRPL13	-1.07746088474995	0.0068359375
COAD	MRPL2	MRPL47	-2.29582381838246	0.00863465666770936
KICH	MRPL2	MRPL43	-2.18179102009894	0.00963503122329712
ESCA	MRPL2	MRPL17	-1.18756178214998	0.009765625
STAD	MRPL2	MRPL47	-1.4008685687155	0.0118026207201183
LIHC	MRPL2	MRPL17	-1.06225729770915	0.0124123499319886
STAD	MRPL2	MRPL4	1.4393539135682	0.0279771662317216
KIRC	MRPL2	MRPL32	-2.79664327578899	0.0376051795400881
LIHC	MRPL2	MRPL47	-6.59586850948538	0.0416658979324166
KIRC	MRPL2	MRPL47	1.74758475364701	1.00533732476669e-06
PRAD	MRPL2	MRPL11	1.12581653394628	1.15996224044503e-05
STAD	MRPL2	MRPL17	-3.90880705449186	1.49570405483246e-06
LIHC	MRPL2	MRPL32	-1.20074144698753	2.24402029682138e-06
COAD	MRPL2	MRPL4	2.77705897514473	2.98023223876954e-07
LUSC	MRPL2	MRPL40	-8.45997214407498	3.09303724812157e-05
LUSC	MRPL2	MRPL17	-6.83409683292749	6.93230040561614e-07
LUAD	MRPL2	MRPL47	-1.74990909879567	9.53955602455483e-07

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPL2

ICT1, CUL3, MRPL11, MRPL9, MRPL37, MRPL4, MRPL23, MRPL14, MRPL24, MRPL40, MRPL13, MRPL16, RPS18, RPS15, FUBP1, SLC25A3, TUFM, DDX28, EIF3C, CMTM4, GRSF1, MRPL28, RPS8, MRPL39, MRPS30, MRPL47, GFM2, GTPBP4, MRPL17, MRPL18, MRPL22, MRPL32, TSR1, TUBA1C, MRPS7, PHB2, POLR3A, EZH2, MRPL50, MRPL1, MASTL, Ncstn, Brwd3, C6orf203, MRPL10, MRPL42, MRPL35, CYLD, DLST, PDHA1, ESR2, MEPCE, LARP7, RECQL4, MRM1, TRMT61B, LTN1, SNRNP70, Dppa3, NFX1, LRRK2, PRKCI, RAB5A, RASA1, nsp6, KIF14, DOCK8, ACAD9, AUH, C12orf65, C17orf80, C1QBP, C21orf33, CCDC90B, CS, GFM1, HINT2, LRPPRC, MDH2, METTL15, METTL17, MRPS12, MRRF, MTERF3, MTG1, MTG2, MTIF3, MTRF1, MTRF1L, NGRN, PMPCA, PMPCB, RPUSD4, TACO1, TBRG4, TMEM70, TRUB2, TSFM, VWA8, HSCB, MRPL33, MRPS22, MRPL44, MRPL41, MRPL38, GADD45GIP1, DDX54, RPL37, MOV10, MRPL53, RBMS2, RPL26, MRPL20, MRPL46, RPL17, HP1BP3, MRPL51, MRPL52, ZCRB1, MRPL55, COX1, MRPL19, RPL27A, MRPS18C, MRPL12, NSA2, MRPL45, DDX21, MRPL48, MRPS24, SUPV3L1, ZNF326, H1FNT, SRSF12, DAP3, MRPL27, MRPL57, YBX2, FTL, ZC3HAV1, RBM45, RPS3A, FASTKD2, DKC1, MRPL15, YARS2, LIN28A, MRPL34, MALSU1, MRPS18A, YBX1, MSI1, RPL26L1, PIPSL, RPL19, MRPS27, MRPS31, RPUSD3, KLHL3, FTSJ3, RPL13A, MRPS5, RBM19, RNMTL1, MRPL21, MRPS35, PTCD1, RPS10, RPS9, SRSF3, HNRNPU, PPP1R9A, MRPL49, MRPL3, MRPS9, GTPBP10, MRPL30, MRPS21, NDUFAB1, RPL35, KRR1, FAHD1, MRPS33, RBMS3, PTCD3, MRPS25, MRPS2, MRPS17, TFB1M, WBSCR16, YBX3, MRPS26, RPS4Y2, MRPS10, MRPS11, MRPS16, ND5, MRPL43, RPL10, OXA1L, MRPS34, APOBEC3D, MRPL54, RPL23A, EXOSC8, CLK2, KLF12,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPL2	BRCA	chr6	43022206	43022206	C	A	Missense_Mutation	p.A242S	4
MRPL2	KIRP	chr6	43023646	43023646	A	C	Missense_Mutation	p.I207S	4
MRPL2	COAD	chr6	43023827	43023827	C	T	Missense_Mutation	p.R171Q	4
MRPL2	STAD	chr6	43023356	43023356	C	A	Missense_Mutation	p.G211V	4
MRPL2	COAD	chr6	43022057	43022057	G	-	Nonsense_Mutation	p.M292X	3
MRPL2	LUAD	chr6	43025848	43025848	T	A	Missense_Mutation	p.I74F	3
MRPL2	BRCA	chr6	43025966	43025966	C	T	Missense_Mutation	p.M34I	3
MRPL2	PRAD	chr6	43023654	43023654	G	A	Silent	p.A204A	3
MRPL2	ESCA	chr6	43024117	43024117	C	T	Missense_Mutation	p.R111H	3
MRPL2	UCEC	chr6	43024149	43024149	G	A	Silent	p.H100	2
MRPL2	SARC	chr6	43023872	43023872	T	A	Missense_Mutation		2
MRPL2	STAD	chr6	43025842	43025842	G	A	Missense_Mutation	p.P76S	2
MRPL2	LGG	chr6	43023893	43023893	C	T	Missense_Mutation	p.R149H	2
MRPL2	STAD	chr6	43024071	43024071	A	C	Silent	p.V126V	2
MRPL2	CHOL	chr6	43022170	43022170	T	C	Missense_Mutation		2
MRPL2	SKCM	chr6	43023662	43023662	G	A	Missense_Mutation	p.R202W	2
MRPL2	CHOL	chr6	43022170	43022170	T	C	Missense_Mutation	p.K254E	2
MRPL2	LUAD	chr6	43023909	43023909	C	A	Missense_Mutation	p.G144W	2
MRPL2	SKCM	chr6	43024063	43024063	A	C	Missense_Mutation	p.V129G	2
MRPL2	SKCM	chr6	43024176	43024176	G	A	Silent	p.I91I	2
MRPL2	UCEC	chr6	43022075	43022075	C	A	Missense_Mutation	p.K285N	2
MRPL2	SKCM	chr6	43025923	43025923	G	A	Missense_Mutation	p.P49S	2
MRPL2	BRCA	chr6	43022095	43022095	C	T	Missense_Mutation	p.G279R	2
MRPL2	UCEC	chr6	43022145	43022145	C	T	Missense_Mutation	p.R262H	2
MRPL2	KIRC	chr6	43024130	43024130	T	G	Missense_Mutation	p.I107L	2
MRPL2	SKCM	chr6	43023883	43023883	G	A	Silent	p.I152I	2
MRPL2	STAD	chr6	43022057	43022057	G	-	Frame_Shift_Del	p.P291fs	2
MRPL2	UCEC	chr6	43023660	43023660	C	A	Silent	p.R202	2
MRPL2	PRAD	chr6	43024050	43024050	G	T	Silent	p.P133P	2
MRPL2	UCEC	chr6	43023675	43023675	T	G	Missense_Mutation	p.E197D	2
MRPL2	UCEC	chr6	43023723	43023723	C	T	Silent	p.A181	2
MRPL2	LIHC	chr6	43027067	43027067	G	-	Frame_Shift_Del	p.P18fs	2
MRPL2	UCEC	chr6	43023737	43023737	G	A	Missense_Mutation	p.R177W	2
MRPL2	STAD	chr6	43022174	43022174	A	G	Silent	p.H252H	2
MRPL2	CESC	chr6	43026954	43026954	C	G	Missense_Mutation	p.E56Q	1
MRPL2	LIHC	chr6	43022130	43022130	C	-	Frame_Shift_Del	p.G267fs	1
MRPL2	GBM	chr6	43024135	43024135	C	T	Missense_Mutation		1
MRPL2	KIRP	chr6	43023646	43023646	A	C	Missense_Mutation		1
MRPL2	THYM	chr6	43027032	43027032	C	T	Missense_Mutation	p.A30T	1
MRPL2	UCS	chr6	43023723	43023723	C	T	Silent		1
MRPL2	CESC	chr6	43027092	43027092	G	A	Silent	p.L10	1
MRPL2	LIHC	chr6	43024086	43024086	G	-	Frame_Shift_Del	p.P121fs	1
MRPL2	HNSC	chr6	43022195	43022195	G	A	Missense_Mutation		1
MRPL2	SARC	chr6	43022099	43022099	G	T	Silent		1
MRPL2	THYM	chr6	43022146	43022146	G	T	Missense_Mutation	p.R262S	1
MRPL2	UCS	chr6	43023723	43023723	C	T	Silent	p.A181A	1
MRPL2	LIHC	chr6	43025783	43025783	C	-	Frame_Shift_Del	p.G95fs	1
MRPL2	HNSC	chr6	43023876	43023876	C	T	Missense_Mutation		1
MRPL2	LGG	chr6	43023921	43023921	C	T	Missense_Mutation	p.A140T	1
MRPL2	UCEC	chr6	43023660	43023660	C	A	Silent	p.R202R	1
MRPL2	HNSC	chr6	43022195	43022195	G	A	Missense_Mutation	p.P221S	1
MRPL2	STAD	chr6	43023644	43023644	G	A	Nonsense_Mutation	p.R208X	1
MRPL2	LGG	chr6	43023893	43023893	C	T	Missense_Mutation		1
MRPL2	UCEC	chr6	43023356	43023356	C	A	Missense_Mutation	p.G211_splice	1
MRPL2	HNSC	chr6	43023876	43023876	C	T	Missense_Mutation	p.E155K	1
MRPL2	STAD	chr6	43023644	43023644	G	A	Nonsense_Mutation	p.R208*	1
MRPL2	BLCA	chr6	43022071	43022071	G	A	Missense_Mutation	p.R287W	1
MRPL2	LGG	chr6	43023921	43023921	C	T	Missense_Mutation		1
MRPL2	COAD	chr6	43022100	43022100	C	T	Missense_Mutation	p.R277H	1
MRPL2	MESO	chr6	43026949	43026949	C	A	Silent		1
MRPL2	HNSC	chr6	43023334	43023335	-	CGCAGT	In_Frame_Ins	p.218_218Q>HCE	1
MRPL2	STAD	chr6	43023745	43023745	A	G	Missense_Mutation	p.V174A	1
MRPL2	LIHC	chr6	43023661	43023661	C	T	Missense_Mutation		1
MRPL2	COAD	chr6	43023336	43023336	G	A	Missense_Mutation	p.R218W	1
MRPL2	OV	chr6	43131724	43131724	C	T	Splice_Site	e5-1	1
MRPL2	LIHC	chr6	43023644	43023644	G	T	Silent		1
MRPL2	COAD	chr6	43025881	43025881	A	C	Missense_Mutation	p.F63V	1
MRPL2	SKCM	chr6	43022060	43022060	G	A	Silent	p.P290P	1
MRPL2	STAD	chr6	43022057	43022057	G	-	Frame_Shift_Del	p.M292fs	1
MRPL2	LIHC	chr6	43023917	43023917	A	G	Missense_Mutation	p.L141P	1
MRPL2	KIRP	chr6	43023807	43023820	GCCATCTCTCACCT	-	Splice_Site	p.A175_splice	1
MRPL2	SKCM	chr6	43023310	43023310	G	A	Silent	p.I226I	1
MRPL2	THYM	chr6	43022139	43022139	C	T	Missense_Mutation		1
MRPL2	CESC	chr6	43027092	43027092	G	A	Silent		1
MRPL2	LIHC	chr6	43023661	43023661	C	T	Missense_Mutation	p.R202Q	1
MRPL2	SARC	chr6	43023722	43023722	G	T	Missense_Mutation		1
MRPL2	KIRP	chr6	43023807	43023820	GCCATCTCTCACCT	-	Frame_Shift_Del	p.174_174del	1
MRPL2	THYM	chr6	43027032	43027032	C	T	Missense_Mutation		1
MRPL2	CESC	chr6	43026954	43026954	C	G	Missense_Mutation		1
MRPL2	ESCA	chr6	43024117	43024117	C	T	Missense_Mutation		1
MRPL2	SARC	chr6	43024059	43024059	G	T	Silent		1
MRPL2	KIRP	chr6	43023807	43023820	GCCATCTCTCACCT	-	Splice_Site	p.V174_splice	1
MRPL2	THYM	chr6	43024110	43024110	C	T	Silent	p.R113R	1

Copy number variation (CNV) of MRPL2
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPL2
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
101039	N/A	AV682978	MRPL2	chr6	43024044	-	DSCAM	chr21	42032682	-
98382	COAD	TCGA-AA-A02F	OBSL1	chr2	220429963	-	MRPL2	chr6	43024183	-
98382	CHOL	TCGA-3X-AAVC-01A	PAFAH1B2	chr11	117015134	+	MRPL2	chr6	43025971	-
98382	Non-Cancer	TCGA-BR-6454-11A	PSMB5	chr14	23502576	-	MRPL2	chr6	43022224	-
98382	STAD	TCGA-FP-7735	TBC1D22B	chr6	37237426	+	MRPL2	chr6	43025971	-
98384	STAD	TCGA-B7-5818	VPS33B	chr15	91542906	-	MRPL2	chr6	43022224	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type	Translation factor	Coefficent	Hazard ratio	Wald test pval	Likelihool ratio pval	Logrank test pval	# samples
KIRC	MRPL2	1.55264814624936	0.439961954588094	0.000359482802032297	0.000518432087441698	0.000365464784786177	604
KIRC	MRPL2	1.55264814624936	0.439961954588094	0.000359482802032297	0.000518432087441698	0.000365464784786177	604
UVM	MRPL2	3.41445096619606	1.22801670885201	0.000794802666284314	0.00105573356096788	0.000616324331960365	80
KIRC	MRPL2	1.30684686336018	0.267617261258942	0.00128978121115966	0.00191678657993441	0.00137904539519825	604
KIRC	MRPL2	1.30684686336018	0.267617261258942	0.00128978121115966	0.00191678657993441	0.00137904539519825	604
BRCA	MRPL2	0.752938740047833	-0.283771409009852	0.00308101257533572	0.00266583034939661	0.00306508335919087	1200
LGG	MRPL2	0.499934868605716	-0.693277451833447	0.00659134952416205	0.00534473830706946	0.00749724951316792	525
BRCA	MRPL2	0.773803325375214	-0.256437539264097	0.00672645522112951	0.00684757493583396	0.00690001050918474	1200
KIRC	MRPL2	1.31460406427513	0.273535528486506	0.0107540759424868	0.0148166816108694	0.0123755993844851	604
KIRC	MRPL2	1.31460406427513	0.273535528486506	0.0107540759424868	0.0148166816108694	0.0123755993844851	604
BRCA	MRPL2	0.767596778026304	-0.264490712321831	0.0120697389901062	0.00947377383073513	0.0122046766044959	1200
SKCM	MRPL2	1.29671049818551	0.259830671618825	0.01210789887392	0.0141232701279272	0.0121885074481852	462
SKCM	MRPL2	1.29671049818551	0.259830671618825	0.01210789887392	0.0141232701279272	0.0121885074481852	462
UVM	MRPL2	2.75920789954138	1.01494364561892	0.0140765143605146	0.013319194123596	0.012909503067063	80
LGG	MRPL2	0.614942350614612	-0.486226754407407	0.0279838678740248	0.0247009903152509	0.0285717916307552	525
SKCM	MRPL2	1.26335056707545	0.233767371817702	0.0313424661396688	0.0323715149887017	0.0314353456226912	462
SKCM	MRPL2	1.26335056707545	0.233767371817702	0.0313424661396688	0.0323715149887017	0.0314353456226912	462
LUSC	MRPL2	0.82234335587782	-0.195597263261048	0.036341142891063	0.0346760856317492	0.0361443925535271	545
LAML	MRPL2	1.53396101163897	0.427853286480586	0.0371370824484364	0.0367409134809413	0.0376829592768664	160
BLCA	MRPL2	0.771992720519477	-0.258780158380734	0.0387940399337093	0.0368852395229482	0.0387531847263431	422
LAML	MRPL2	0.505907127042516	-0.681402169935058	0.0416045655228545	0.0433413127080856	0.04188293241739	160
BRCA	MRPL2	0.702472512127359	-0.35314900718411	3.61410249191058e-05	3.34909284479143e-05	4.03597905430731e-05	1200

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	MRPL2	0.0077680362671528	0.22
HNSC	MRPL2	0.0192841701277387	0.52
MESO	MRPL2	0.0236692330055214	0.62

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	MRPL2	0.0106515977410836	0.31
STAD	MRPL2	0.0259207234755463	0.73
LUSC	MRPL2	0.00924705136922194	0.28
THCA	MRPL2	0.00600693328897654	0.19
LGG	MRPL2	4.7236458459573e-06	0.00016
PAAD	MRPL2	0.00373736955503483	0.12

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source