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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: ZC3H15 (NCBI Gene ID:55854)

Gene Summary

Gene Summary

Gene Information	Gene Name: ZC3H15
	Gene ID: 55854
	Gene Symbol	ZC3H15
	Gene ID	55854
	Gene Name	zinc finger CCCH-type containing 15
	Synonyms	HT010\|LEREPO4\|MSTP012
	Cytomap	2q32.1
	Type of Gene	protein-coding
	Description	zinc finger CCCH domain-containing protein 15DRG family-regulatory protein 1likely ortholog of mouse immediate early response erythropoietin 4
	Modification date	20200313
	UniProtAcc	Q8WU90

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ZC3H15	GO:0043547	positive regulation of GTPase activity	23711155

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
ZC3H15	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'ZC3H15[title] AND translation [title] AND human.'

Gene	Title	PMID
ZC3H15	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000337859	187367222	187367314	Frame-shift
ENST00000337859	187370177	187370324	In-frame
ENST00000337859	187371439	187371563	Frame-shift

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000337859	187370177	187370324	2155	945	1091	426	239	288

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q8WU90	239	288	1	426	Chain	ID=PRO_0000324642;Note=Zinc finger CCCH domain-containing protein 15
Q8WU90	239	288	236	260	Region	Note=Required for interaction with DRG1;Ontology_term=ECO:0000250;evidence=ECO:0000250
Q8WU90	239	288	218	285	Coiled coil	Ontology_term=ECO:0000255;evidence=ECO:0000255

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
STAD	ZC3H15	-1.04968618173197	0.00733334058895707
BLCA	ZC3H15	1.07480871713981	0.0258216857910156

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type	Gene	miRNA	TargetScan binding score (Context++ score percentile)	Coefficient	Pvalue
STAD	ZC3H15	hsa-miR-429	91	-0.314168113705061	0.00741909699468949

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
LAML	ZC3H15	0.069142842	0.000872993
READ	ZC3H15	-0.059978569	0.039787984

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with ZC3H15 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	CGC	ZC3H15	RAD21	0.835176981	1.58E-13
KICH	Cell metabolism gene	ZC3H15	RPE	0.848041326	2.83E-26
KICH	Epifactor	ZC3H15	ATF2	0.804723978	7.28E-22
KICH	Epifactor	ZC3H15	SMEK2	0.826053768	6.96E-24
KICH	Epifactor	ZC3H15	HAT1	0.826215557	6.70E-24
KICH	IUPHAR	ZC3H15	HAT1	0.826215557	6.70E-24
KICH	IUPHAR	ZC3H15	SLC30A6	0.829302566	3.24E-24
KICH	TF	ZC3H15	ATF2	0.804723978	7.28E-22
KICH	TF	ZC3H15	SP3	0.810936859	2.00E-22
KICH	TF	ZC3H15	CEBPZ	0.89127009	2.56E-32
KICH	TSG	ZC3H15	XRCC5	0.853126011	6.98E-27
SKCM	Cell metabolism gene	ZC3H15	XPO1	0.809448088	3.31E-111
SKCM	Cell metabolism gene	ZC3H15	RPE	0.815426796	3.87E-114
SKCM	CGC	ZC3H15	XPO1	0.809448088	3.31E-111
SKCM	CGC	ZC3H15	CUL3	0.824352588	1.01E-118
SKCM	CGC	ZC3H15	PMS1	0.837379258	6.76E-126
SKCM	Epifactor	ZC3H15	SMEK2	0.800964366	3.22E-107
SKCM	Epifactor	ZC3H15	HAT1	0.815592562	3.20E-114
SKCM	Epifactor	ZC3H15	CUL3	0.824352588	1.01E-118
SKCM	IUPHAR	ZC3H15	XPO1	0.809448088	3.31E-111
SKCM	IUPHAR	ZC3H15	HAT1	0.815592562	3.20E-114
SKCM	TF	ZC3H15	CEBPZ	0.845150582	1.74E-130
TGCT	Cell metabolism gene	ZC3H15	NUP35	0.803287548	1.75E-36
THYM	Cell metabolism gene	ZC3H15	PI4K2B	0.811777126	8.26E-30
THYM	Cell metabolism gene	ZC3H15	TRMT11	0.815067589	3.18E-30
THYM	Cell metabolism gene	ZC3H15	GALK2	0.815683216	2.66E-30
THYM	Cell metabolism gene	ZC3H15	NUP54	0.816027091	2.40E-30
THYM	Cell metabolism gene	ZC3H15	NUP205	0.819065141	9.74E-31
THYM	Cell metabolism gene	ZC3H15	ACADM	0.819499624	8.55E-31
THYM	Cell metabolism gene	ZC3H15	CDK8	0.824906349	1.64E-31
THYM	Cell metabolism gene	ZC3H15	RQCD1	0.836245338	4.22E-33
THYM	Cell metabolism gene	ZC3H15	SRP54	0.837198834	3.06E-33
THYM	Cell metabolism gene	ZC3H15	SCP2	0.837653802	2.63E-33
THYM	Cell metabolism gene	ZC3H15	TGS1	0.843864206	3.07E-34
THYM	Cell metabolism gene	ZC3H15	ENOPH1	0.844407975	2.54E-34
THYM	Cell metabolism gene	ZC3H15	NUP107	0.861303854	4.34E-37
THYM	Cell metabolism gene	ZC3H15	MED17	0.865760226	7.03E-38
THYM	Cell metabolism gene	ZC3H15	POLR2B	0.880157918	1.21E-40
THYM	CGC	ZC3H15	ERCC3	0.802958462	9.71E-29
THYM	CGC	ZC3H15	BCOR	0.814006851	4.34E-30
THYM	CGC	ZC3H15	RAD21	0.822228617	3.74E-31
THYM	CGC	ZC3H15	ABI1	0.832521705	1.45E-32
THYM	CGC	ZC3H15	RB1	0.832597375	1.41E-32
THYM	CGC	ZC3H15	ZCCHC8	0.858106912	1.54E-36
THYM	CGC	ZC3H15	TOP1	0.915502999	2.80E-49
THYM	Epifactor	ZC3H15	MEAF6	0.80392255	7.47E-29
THYM	Epifactor	ZC3H15	ZNF217	0.811981387	7.79E-30
THYM	Epifactor	ZC3H15	BCOR	0.814006851	4.34E-30
THYM	Epifactor	ZC3H15	ACTL6A	0.819861195	7.67E-31
THYM	Epifactor	ZC3H15	RCOR1	0.82201285	3.99E-31
THYM	Epifactor	ZC3H15	DR1	0.825914334	1.20E-31
THYM	Epifactor	ZC3H15	RB1	0.832597375	1.41E-32
THYM	Epifactor	ZC3H15	CUL2	0.83275984	1.34E-32
THYM	Epifactor	ZC3H15	RBBP4	0.833106501	1.19E-32
THYM	Epifactor	ZC3H15	TAF4	0.835196107	5.99E-33
THYM	Epifactor	ZC3H15	ACTR6	0.835791612	4.91E-33
THYM	Epifactor	ZC3H15	TADA1	0.841556634	6.89E-34
THYM	Epifactor	ZC3H15	UCHL5	0.841642004	6.69E-34
THYM	Epifactor	ZC3H15	TAF2	0.844609014	2.36E-34
THYM	Epifactor	ZC3H15	SMARCAD1	0.849729716	3.71E-35
THYM	Epifactor	ZC3H15	SMEK2	0.852540279	1.31E-35
THYM	Epifactor	ZC3H15	YY1	0.865939791	6.53E-38
THYM	Epifactor	ZC3H15	MASTL	0.86834419	2.37E-38
THYM	IUPHAR	ZC3H15	PI4K2B	0.811777126	8.26E-30
THYM	IUPHAR	ZC3H15	MAPK8	0.81303918	5.74E-30
THYM	IUPHAR	ZC3H15	CDK8	0.824906349	1.64E-31
THYM	IUPHAR	ZC3H15	PRMT3	0.83140944	2.08E-32
THYM	IUPHAR	ZC3H15	MASTL	0.86834419	2.37E-38
THYM	IUPHAR	ZC3H15	TOP1	0.915502999	2.80E-49
THYM	Kinase	ZC3H15	MAPK8	0.81303918	5.74E-30
THYM	Kinase	ZC3H15	CDK8	0.824906349	1.64E-31
THYM	Kinase	ZC3H15	MASTL	0.86834419	2.37E-38
THYM	TF	ZC3H15	TOPORS	0.805371659	5.01E-29
THYM	TF	ZC3H15	CDC5L	0.806448154	3.72E-29
THYM	TF	ZC3H15	ZNF227	0.807308109	2.93E-29
THYM	TF	ZC3H15	ZNF28	0.811550599	8.81E-30
THYM	TF	ZC3H15	ZNF217	0.811981387	7.79E-30
THYM	TF	ZC3H15	ZNF184	0.812190966	7.33E-30
THYM	TF	ZC3H15	ZBTB1	0.81486815	3.37E-30
THYM	TF	ZC3H15	SP3	0.821031462	5.38E-31
THYM	TF	ZC3H15	ZUFSP	0.822221984	3.75E-31
THYM	TF	ZC3H15	ZNF830	0.822989688	2.96E-31
THYM	TF	ZC3H15	DR1	0.825914334	1.20E-31
THYM	TF	ZC3H15	PRMT3	0.83140944	2.08E-32
THYM	TF	ZC3H15	ELF1	0.839077865	1.62E-33
THYM	TF	ZC3H15	ZNF567	0.842375365	5.18E-34
THYM	TF	ZC3H15	ZNF468	0.855389117	4.43E-36
THYM	TF	ZC3H15	YY1	0.865939791	6.53E-38
THYM	TSG	ZC3H15	TANK	0.800685569	1.80E-28
THYM	TSG	ZC3H15	TOPORS	0.805371659	5.01E-29
THYM	TSG	ZC3H15	LIN9	0.826913826	8.73E-32
THYM	TSG	ZC3H15	RANBP9	0.829387089	3.98E-32
THYM	TSG	ZC3H15	INTS6	0.832273557	1.57E-32
THYM	TSG	ZC3H15	RB1	0.832597375	1.41E-32
THYM	TSG	ZC3H15	CUL2	0.83275984	1.34E-32
THYM	TSG	ZC3H15	CCAR1	0.878105519	3.16E-40
UCS	Cell metabolism gene	ZC3H15	PI4K2B	0.811777126	8.26E-30
UCS	Cell metabolism gene	ZC3H15	TRMT11	0.815067589	3.18E-30
UCS	Cell metabolism gene	ZC3H15	GALK2	0.815683216	2.66E-30
UCS	Cell metabolism gene	ZC3H15	NUP54	0.816027091	2.40E-30
UCS	Cell metabolism gene	ZC3H15	NUP205	0.819065141	9.74E-31
UCS	Cell metabolism gene	ZC3H15	ACADM	0.819499624	8.55E-31
UCS	Cell metabolism gene	ZC3H15	CDK8	0.824906349	1.64E-31
UCS	Cell metabolism gene	ZC3H15	RQCD1	0.836245338	4.22E-33
UCS	Cell metabolism gene	ZC3H15	SRP54	0.837198834	3.06E-33
UCS	Cell metabolism gene	ZC3H15	SCP2	0.837653802	2.63E-33
UCS	Cell metabolism gene	ZC3H15	TGS1	0.843864206	3.07E-34
UCS	Cell metabolism gene	ZC3H15	ENOPH1	0.844407975	2.54E-34
UCS	Cell metabolism gene	ZC3H15	NUP107	0.861303854	4.34E-37
UCS	Cell metabolism gene	ZC3H15	MED17	0.865760226	7.03E-38
UCS	Cell metabolism gene	ZC3H15	POLR2B	0.880157918	1.21E-40
UCS	CGC	ZC3H15	ERCC3	0.802958462	9.71E-29
UCS	CGC	ZC3H15	BCOR	0.814006851	4.34E-30
UCS	CGC	ZC3H15	RAD21	0.822228617	3.74E-31
UCS	CGC	ZC3H15	ABI1	0.832521705	1.45E-32
UCS	CGC	ZC3H15	RB1	0.832597375	1.41E-32
UCS	CGC	ZC3H15	ZCCHC8	0.858106912	1.54E-36
UCS	CGC	ZC3H15	TOP1	0.915502999	2.80E-49
UCS	Epifactor	ZC3H15	MEAF6	0.80392255	7.47E-29
UCS	Epifactor	ZC3H15	ZNF217	0.811981387	7.79E-30
UCS	Epifactor	ZC3H15	BCOR	0.814006851	4.34E-30
UCS	Epifactor	ZC3H15	ACTL6A	0.819861195	7.67E-31
UCS	Epifactor	ZC3H15	RCOR1	0.82201285	3.99E-31
UCS	Epifactor	ZC3H15	DR1	0.825914334	1.20E-31
UCS	Epifactor	ZC3H15	RB1	0.832597375	1.41E-32
UCS	Epifactor	ZC3H15	CUL2	0.83275984	1.34E-32
UCS	Epifactor	ZC3H15	RBBP4	0.833106501	1.19E-32
UCS	Epifactor	ZC3H15	TAF4	0.835196107	5.99E-33
UCS	Epifactor	ZC3H15	ACTR6	0.835791612	4.91E-33
UCS	Epifactor	ZC3H15	TADA1	0.841556634	6.89E-34
UCS	Epifactor	ZC3H15	UCHL5	0.841642004	6.69E-34
UCS	Epifactor	ZC3H15	TAF2	0.844609014	2.36E-34
UCS	Epifactor	ZC3H15	SMARCAD1	0.849729716	3.71E-35
UCS	Epifactor	ZC3H15	SMEK2	0.852540279	1.31E-35
UCS	Epifactor	ZC3H15	YY1	0.865939791	6.53E-38
UCS	Epifactor	ZC3H15	MASTL	0.86834419	2.37E-38
UCS	IUPHAR	ZC3H15	PI4K2B	0.811777126	8.26E-30
UCS	IUPHAR	ZC3H15	MAPK8	0.81303918	5.74E-30
UCS	IUPHAR	ZC3H15	CDK8	0.824906349	1.64E-31
UCS	IUPHAR	ZC3H15	PRMT3	0.83140944	2.08E-32
UCS	IUPHAR	ZC3H15	MASTL	0.86834419	2.37E-38
UCS	IUPHAR	ZC3H15	TOP1	0.915502999	2.80E-49
UCS	Kinase	ZC3H15	MAPK8	0.81303918	5.74E-30
UCS	Kinase	ZC3H15	CDK8	0.824906349	1.64E-31
UCS	Kinase	ZC3H15	MASTL	0.86834419	2.37E-38
UCS	TF	ZC3H15	TOPORS	0.805371659	5.01E-29
UCS	TF	ZC3H15	CDC5L	0.806448154	3.72E-29
UCS	TF	ZC3H15	ZNF227	0.807308109	2.93E-29
UCS	TF	ZC3H15	ZNF28	0.811550599	8.81E-30
UCS	TF	ZC3H15	ZNF217	0.811981387	7.79E-30
UCS	TF	ZC3H15	ZNF184	0.812190966	7.33E-30
UCS	TF	ZC3H15	ZBTB1	0.81486815	3.37E-30
UCS	TF	ZC3H15	SP3	0.821031462	5.38E-31
UCS	TF	ZC3H15	ZUFSP	0.822221984	3.75E-31
UCS	TF	ZC3H15	ZNF830	0.822989688	2.96E-31
UCS	TF	ZC3H15	DR1	0.825914334	1.20E-31
UCS	TF	ZC3H15	PRMT3	0.83140944	2.08E-32
UCS	TF	ZC3H15	ELF1	0.839077865	1.62E-33
UCS	TF	ZC3H15	ZNF567	0.842375365	5.18E-34
UCS	TF	ZC3H15	ZNF468	0.855389117	4.43E-36
UCS	TF	ZC3H15	YY1	0.865939791	6.53E-38
UCS	TSG	ZC3H15	TANK	0.800685569	1.80E-28
UCS	TSG	ZC3H15	TOPORS	0.805371659	5.01E-29
UCS	TSG	ZC3H15	LIN9	0.826913826	8.73E-32
UCS	TSG	ZC3H15	RANBP9	0.829387089	3.98E-32
UCS	TSG	ZC3H15	INTS6	0.832273557	1.57E-32
UCS	TSG	ZC3H15	RB1	0.832597375	1.41E-32
UCS	TSG	ZC3H15	CUL2	0.83275984	1.34E-32
UCS	TSG	ZC3H15	CCAR1	0.878105519	3.16E-40
UVM	Cell metabolism gene	ZC3H15	NUP35	0.801435857	4.31E-19
UVM	Cell metabolism gene	ZC3H15	DCP2	0.801738901	4.09E-19
UVM	Cell metabolism gene	ZC3H15	TXNRD1	0.802336937	3.68E-19
UVM	Cell metabolism gene	ZC3H15	DDX20	0.802834988	3.37E-19
UVM	Cell metabolism gene	ZC3H15	ENOPH1	0.804317513	2.59E-19
UVM	Cell metabolism gene	ZC3H15	DLD	0.80443723	2.53E-19
UVM	Cell metabolism gene	ZC3H15	GCLC	0.804532734	2.49E-19
UVM	Cell metabolism gene	ZC3H15	CPOX	0.805441418	2.11E-19
UVM	Cell metabolism gene	ZC3H15	SGPP1	0.807925779	1.35E-19
UVM	Cell metabolism gene	ZC3H15	PIP5K1A	0.809732957	9.67E-20
UVM	Cell metabolism gene	ZC3H15	UGCG	0.810129202	8.99E-20
UVM	Cell metabolism gene	ZC3H15	HIF1A	0.810187974	8.89E-20
UVM	Cell metabolism gene	ZC3H15	FUT8	0.810606762	8.23E-20
UVM	Cell metabolism gene	ZC3H15	PIK3CA	0.811480752	6.99E-20
UVM	Cell metabolism gene	ZC3H15	EPRS	0.811662237	6.76E-20
UVM	Cell metabolism gene	ZC3H15	PAFAH1B1	0.81178663	6.60E-20
UVM	Cell metabolism gene	ZC3H15	XRN2	0.812952726	5.31E-20
UVM	Cell metabolism gene	ZC3H15	UGP2	0.813426221	4.85E-20
UVM	Cell metabolism gene	ZC3H15	SUCLA2	0.814776002	3.76E-20
UVM	Cell metabolism gene	ZC3H15	CNOT2	0.817479582	2.24E-20
UVM	Cell metabolism gene	ZC3H15	CDK8	0.819297192	1.57E-20
UVM	Cell metabolism gene	ZC3H15	SRP54	0.819836077	1.41E-20
UVM	Cell metabolism gene	ZC3H15	MED4	0.819953577	1.38E-20
UVM	Cell metabolism gene	ZC3H15	AZIN1	0.820188098	1.32E-20
UVM	Cell metabolism gene	ZC3H15	FPGT	0.820654395	1.20E-20
UVM	Cell metabolism gene	ZC3H15	MGAT2	0.82077286	1.18E-20
UVM	Cell metabolism gene	ZC3H15	PDHX	0.822658484	8.09E-21
UVM	Cell metabolism gene	ZC3H15	SDHD	0.824625186	5.45E-21
UVM	Cell metabolism gene	ZC3H15	MTR	0.82523774	4.81E-21
UVM	Cell metabolism gene	ZC3H15	SEC24B	0.825585762	4.48E-21
UVM	Cell metabolism gene	ZC3H15	VAPA	0.828350594	2.54E-21
UVM	Cell metabolism gene	ZC3H15	SPTLC1	0.830897788	1.49E-21
UVM	Cell metabolism gene	ZC3H15	GXYLT1	0.835186455	5.98E-22
UVM	Cell metabolism gene	ZC3H15	PITPNB	0.835743047	5.30E-22
UVM	Cell metabolism gene	ZC3H15	GPAM	0.836256249	4.74E-22
UVM	Cell metabolism gene	ZC3H15	PPP1CB	0.836530151	4.46E-22
UVM	Cell metabolism gene	ZC3H15	PSMD12	0.836763896	4.24E-22
UVM	Cell metabolism gene	ZC3H15	ACADSB	0.836856197	4.16E-22
UVM	Cell metabolism gene	ZC3H15	SMG1	0.836954451	4.07E-22
UVM	Cell metabolism gene	ZC3H15	COL4A3BP	0.83899491	2.59E-22
UVM	Cell metabolism gene	ZC3H15	MANEA	0.839694827	2.22E-22
UVM	Cell metabolism gene	ZC3H15	PIGA	0.839945006	2.10E-22
UVM	Cell metabolism gene	ZC3H15	PI4K2B	0.841702499	1.41E-22
UVM	Cell metabolism gene	ZC3H15	ARFGEF2	0.841746488	1.40E-22
UVM	Cell metabolism gene	ZC3H15	PSMA4	0.841989898	1.32E-22
UVM	Cell metabolism gene	ZC3H15	VBP1	0.842071601	1.30E-22
UVM	Cell metabolism gene	ZC3H15	MINPP1	0.843286537	9.85E-23
UVM	Cell metabolism gene	ZC3H15	ALG13	0.843782222	8.80E-23
UVM	Cell metabolism gene	ZC3H15	MCEE	0.843967204	8.43E-23
UVM	Cell metabolism gene	ZC3H15	SRP19	0.844911677	6.78E-23
UVM	Cell metabolism gene	ZC3H15	MED7	0.845468196	5.96E-23
UVM	Cell metabolism gene	ZC3H15	SRP72	0.845877598	5.42E-23
UVM	Cell metabolism gene	ZC3H15	PSME4	0.84602252	5.24E-23
UVM	Cell metabolism gene	ZC3H15	IDI1	0.847378386	3.81E-23
UVM	Cell metabolism gene	ZC3H15	HMGCS1	0.848746338	2.76E-23
UVM	Cell metabolism gene	ZC3H15	TGS1	0.848842044	2.69E-23
UVM	Cell metabolism gene	ZC3H15	DCK	0.848934426	2.64E-23
UVM	Cell metabolism gene	ZC3H15	HMGCR	0.850332221	1.89E-23
UVM	Cell metabolism gene	ZC3H15	DBT	0.850536972	1.80E-23
UVM	Cell metabolism gene	ZC3H15	EPT1	0.850853163	1.66E-23
UVM	Cell metabolism gene	ZC3H15	POLR2B	0.852617636	1.08E-23
UVM	Cell metabolism gene	ZC3H15	CSGALNACT2	0.852686556	1.07E-23
UVM	Cell metabolism gene	ZC3H15	PLA2G12A	0.853784676	8.13E-24
UVM	Cell metabolism gene	ZC3H15	PIK3C2A	0.854089601	7.54E-24
UVM	Cell metabolism gene	ZC3H15	BPNT1	0.854909902	6.15E-24
UVM	Cell metabolism gene	ZC3H15	ALG10B	0.855292843	5.59E-24
UVM	Cell metabolism gene	ZC3H15	L2HGDH	0.856837277	3.79E-24
UVM	Cell metabolism gene	ZC3H15	RPE	0.856965223	3.67E-24
UVM	Cell metabolism gene	ZC3H15	FBXL3	0.858426503	2.53E-24
UVM	Cell metabolism gene	ZC3H15	NUPL1	0.858653395	2.39E-24
UVM	Cell metabolism gene	ZC3H15	ETNK1	0.862806159	8.12E-25
UVM	Cell metabolism gene	ZC3H15	ACSL4	0.863585156	6.60E-25
UVM	Cell metabolism gene	ZC3H15	PIK3C3	0.866008301	3.44E-25
UVM	Cell metabolism gene	ZC3H15	LYPLA1	0.866065549	3.39E-25
UVM	Cell metabolism gene	ZC3H15	DLAT	0.866948686	2.66E-25
UVM	Cell metabolism gene	ZC3H15	AASDHPPT	0.867010548	2.62E-25
UVM	Cell metabolism gene	ZC3H15	PANK3	0.869466218	1.33E-25
UVM	Cell metabolism gene	ZC3H15	NUP107	0.869889183	1.18E-25
UVM	Cell metabolism gene	ZC3H15	AGPS	0.870186457	1.09E-25
UVM	Cell metabolism gene	ZC3H15	SEH1L	0.87186417	6.76E-26
UVM	Cell metabolism gene	ZC3H15	FAR1	0.872321538	5.94E-26
UVM	Cell metabolism gene	ZC3H15	GNPDA2	0.872447978	5.73E-26
UVM	Cell metabolism gene	ZC3H15	GPD2	0.875577353	2.31E-26
UVM	Cell metabolism gene	ZC3H15	CNOT8	0.875673056	2.25E-26
UVM	Cell metabolism gene	ZC3H15	PIKFYVE	0.875929677	2.08E-26
UVM	Cell metabolism gene	ZC3H15	PNPLA8	0.877274587	1.40E-26
UVM	Cell metabolism gene	ZC3H15	SACM1L	0.878203297	1.06E-26
UVM	Cell metabolism gene	ZC3H15	NUPL2	0.878430377	9.89E-27
UVM	Cell metabolism gene	ZC3H15	PHAX	0.878534859	9.59E-27
UVM	Cell metabolism gene	ZC3H15	NAMPT	0.879862299	6.41E-27
UVM	Cell metabolism gene	ZC3H15	CLOCK	0.880810834	4.79E-27
UVM	Cell metabolism gene	ZC3H15	NUDT12	0.883685272	1.96E-27
UVM	Cell metabolism gene	ZC3H15	PRKAA1	0.884415376	1.55E-27
UVM	Cell metabolism gene	ZC3H15	UGGT2	0.887636559	5.50E-28
UVM	Cell metabolism gene	ZC3H15	CCT2	0.888196671	4.57E-28
UVM	Cell metabolism gene	ZC3H15	LCLAT1	0.892525992	1.07E-28
UVM	Cell metabolism gene	ZC3H15	RANBP2	0.895576721	3.68E-29
UVM	Cell metabolism gene	ZC3H15	GRPEL2	0.896116459	3.04E-29
UVM	Cell metabolism gene	ZC3H15	MED17	0.897999046	1.55E-29
UVM	Cell metabolism gene	ZC3H15	PSMD14	0.90141241	4.38E-30
UVM	Cell metabolism gene	ZC3H15	TNPO1	0.901745748	3.86E-30
UVM	Cell metabolism gene	ZC3H15	DIS3	0.902838219	2.55E-30
UVM	Cell metabolism gene	ZC3H15	PPAT	0.909227543	2.03E-31
UVM	Cell metabolism gene	ZC3H15	EDEM3	0.910105483	1.42E-31
UVM	Cell metabolism gene	ZC3H15	MTMR6	0.912640802	4.87E-32
UVM	Cell metabolism gene	ZC3H15	PSMC6	0.916403136	9.41E-33
UVM	Cell metabolism gene	ZC3H15	NUP50	0.927933098	3.60E-35
UVM	Cell metabolism gene	ZC3H15	XPO1	0.940145258	3.26E-38
UVM	CGC	ZC3H15	TCF12	0.800830313	4.80E-19
UVM	CGC	ZC3H15	CASP8	0.801781427	4.06E-19
UVM	CGC	ZC3H15	MAP2K4	0.802104016	3.84E-19
UVM	CGC	ZC3H15	TRIP11	0.804771797	2.39E-19
UVM	CGC	ZC3H15	SS18L1	0.80527	2.18E-19
UVM	CGC	ZC3H15	IL6ST	0.80842031	1.23E-19
UVM	CGC	ZC3H15	TRIM33	0.810072956	9.08E-20
UVM	CGC	ZC3H15	HIF1A	0.810187974	8.89E-20
UVM	CGC	ZC3H15	PIK3CA	0.811480752	6.99E-20
UVM	CGC	ZC3H15	AFF4	0.815112637	3.53E-20
UVM	CGC	ZC3H15	TRIM24	0.815156291	3.50E-20
UVM	CGC	ZC3H15	TET2	0.815539274	3.25E-20
UVM	CGC	ZC3H15	ARHGAP5	0.815590386	3.22E-20
UVM	CGC	ZC3H15	MLLT10	0.818319588	1.90E-20
UVM	CGC	ZC3H15	AKAP9	0.822167106	8.92E-21
UVM	CGC	ZC3H15	EZH2	0.823162233	7.31E-21
UVM	CGC	ZC3H15	SDHD	0.824625186	5.45E-21
UVM	CGC	ZC3H15	PALB2	0.82569447	4.39E-21
UVM	CGC	ZC3H15	APC	0.826222377	3.94E-21
UVM	CGC	ZC3H15	ATRX	0.826392823	3.80E-21
UVM	CGC	ZC3H15	N4BP2	0.82859539	2.42E-21
UVM	CGC	ZC3H15	RGPD3	0.829864279	1.86E-21
UVM	CGC	ZC3H15	ERCC4	0.830142125	1.75E-21
UVM	CGC	ZC3H15	SMAD4	0.833465279	8.66E-22
UVM	CGC	ZC3H15	BIRC6	0.834072456	7.60E-22
UVM	CGC	ZC3H15	ITGAV	0.837913801	3.29E-22
UVM	CGC	ZC3H15	DEK	0.838271072	3.04E-22
UVM	CGC	ZC3H15	JAK2	0.838702719	2.77E-22
UVM	CGC	ZC3H15	DICER1	0.840456424	1.87E-22
UVM	CGC	ZC3H15	EML4	0.84112331	1.61E-22
UVM	CGC	ZC3H15	ATF1	0.845476613	5.95E-23
UVM	CGC	ZC3H15	PHF6	0.845890547	5.40E-23
UVM	CGC	ZC3H15	BCLAF1	0.84726029	3.92E-23
UVM	CGC	ZC3H15	ARID2	0.849133248	2.51E-23
UVM	CGC	ZC3H15	ABI1	0.84980942	2.14E-23
UVM	CGC	ZC3H15	GOLGA5	0.854045937	7.62E-24
UVM	CGC	ZC3H15	NBN	0.85432218	7.12E-24
UVM	CGC	ZC3H15	HNRNPA2B1	0.854726974	6.44E-24
UVM	CGC	ZC3H15	KTN1	0.855890961	4.82E-24
UVM	CGC	ZC3H15	TOP1	0.859167619	2.10E-24
UVM	CGC	ZC3H15	KRAS	0.859355482	2.00E-24
UVM	CGC	ZC3H15	FIP1L1	0.860657678	1.43E-24
UVM	CGC	ZC3H15	ZMYM2	0.8625589	8.66E-25
UVM	CGC	ZC3H15	ETNK1	0.862806159	8.12E-25
UVM	CGC	ZC3H15	BRCA2	0.86311433	7.48E-25
UVM	CGC	ZC3H15	RAD21	0.86567664	3.77E-25
UVM	CGC	ZC3H15	DDX5	0.868057707	1.97E-25
UVM	CGC	ZC3H15	POT1	0.868931993	1.54E-25
UVM	CGC	ZC3H15	NFE2L2	0.870886303	8.92E-26
UVM	CGC	ZC3H15	HSP90AA1	0.871117861	8.36E-26
UVM	CGC	ZC3H15	PWWP2A	0.874215962	3.44E-26
UVM	CGC	ZC3H15	RAD17	0.875924314	2.09E-26
UVM	CGC	ZC3H15	STAG2	0.876106969	1.98E-26
UVM	CGC	ZC3H15	RABEP1	0.8801711	5.83E-27
UVM	CGC	ZC3H15	DDX10	0.880385784	5.46E-27
UVM	CGC	ZC3H15	BMPR1A	0.880450527	5.36E-27
UVM	CGC	ZC3H15	USP8	0.884796873	1.38E-27
UVM	CGC	ZC3H15	MSH2	0.890946687	1.83E-28
UVM	CGC	ZC3H15	RANBP2	0.895576721	3.68E-29
UVM	CGC	ZC3H15	CDC73	0.904833399	1.18E-30
UVM	CGC	ZC3H15	KIF5B	0.907101273	4.82E-31
UVM	CGC	ZC3H15	ATM	0.907738771	3.73E-31
UVM	CGC	ZC3H15	FBXO11	0.911124918	9.26E-32
UVM	CGC	ZC3H15	CREB1	0.911136983	9.21E-32
UVM	CGC	ZC3H15	BAZ1A	0.912962305	4.25E-32
UVM	CGC	ZC3H15	SUZ12	0.915247731	1.57E-32
UVM	CGC	ZC3H15	SF3B1	0.920246714	1.62E-33
UVM	CGC	ZC3H15	CUL3	0.931354942	5.77E-36
UVM	CGC	ZC3H15	PMS1	0.939031271	6.55E-38
UVM	CGC	ZC3H15	XPO1	0.940145258	3.26E-38
UVM	Epifactor	ZC3H15	MGA	0.803794628	2.84E-19
UVM	Epifactor	ZC3H15	MBTD1	0.804076634	2.70E-19
UVM	Epifactor	ZC3H15	GATAD1	0.804527386	2.49E-19
UVM	Epifactor	ZC3H15	SS18L1	0.80527	2.18E-19
UVM	Epifactor	ZC3H15	WAC	0.806059205	1.89E-19
UVM	Epifactor	ZC3H15	TRIM33	0.810072956	9.08E-20
UVM	Epifactor	ZC3H15	MPHOSPH8	0.810310856	8.69E-20
UVM	Epifactor	ZC3H15	RSF1	0.810511872	8.37E-20
UVM	Epifactor	ZC3H15	ZMYND11	0.8120003	6.35E-20
UVM	Epifactor	ZC3H15	SUDS3	0.813325591	4.95E-20
UVM	Epifactor	ZC3H15	TADA1	0.814717277	3.80E-20
UVM	Epifactor	ZC3H15	TRIM24	0.815156291	3.50E-20
UVM	Epifactor	ZC3H15	TET2	0.815539274	3.25E-20
UVM	Epifactor	ZC3H15	TLK2	0.817243277	2.34E-20
UVM	Epifactor	ZC3H15	TAF1	0.81760543	2.18E-20
UVM	Epifactor	ZC3H15	MLLT10	0.818319588	1.90E-20
UVM	Epifactor	ZC3H15	HCFC2	0.818365566	1.88E-20
UVM	Epifactor	ZC3H15	SUPT7L	0.818834508	1.72E-20
UVM	Epifactor	ZC3H15	DDX50	0.819015882	1.66E-20
UVM	Epifactor	ZC3H15	PHIP	0.82024836	1.30E-20
UVM	Epifactor	ZC3H15	TAF9	0.820852493	1.16E-20
UVM	Epifactor	ZC3H15	EZH2	0.823162233	7.31E-21
UVM	Epifactor	ZC3H15	ATRX	0.826392823	3.80E-21
UVM	Epifactor	ZC3H15	VRK1	0.829909973	1.84E-21
UVM	Epifactor	ZC3H15	EPC1	0.831718248	1.26E-21
UVM	Epifactor	ZC3H15	SP100	0.832819062	9.94E-22
UVM	Epifactor	ZC3H15	LEO1	0.836889671	4.13E-22
UVM	Epifactor	ZC3H15	RCOR3	0.8372008	3.85E-22
UVM	Epifactor	ZC3H15	ANP32E	0.837532657	3.58E-22
UVM	Epifactor	ZC3H15	TAF2	0.83783322	3.35E-22
UVM	Epifactor	ZC3H15	DEK	0.838271072	3.04E-22
UVM	Epifactor	ZC3H15	JAK2	0.838702719	2.77E-22
UVM	Epifactor	ZC3H15	BRMS1L	0.840199741	1.98E-22
UVM	Epifactor	ZC3H15	BRWD3	0.840729152	1.76E-22
UVM	Epifactor	ZC3H15	BRWD1	0.841574043	1.45E-22
UVM	Epifactor	ZC3H15	CTBP2	0.844482367	7.49E-23
UVM	Epifactor	ZC3H15	RAD54B	0.845091854	6.50E-23
UVM	Epifactor	ZC3H15	UHRF2	0.845750482	5.58E-23
UVM	Epifactor	ZC3H15	ZBTB33	0.845765679	5.56E-23
UVM	Epifactor	ZC3H15	CHD9	0.848832834	2.70E-23
UVM	Epifactor	ZC3H15	DNAJC2	0.849106211	2.53E-23
UVM	Epifactor	ZC3H15	ARID2	0.849133248	2.51E-23
UVM	Epifactor	ZC3H15	ARID4B	0.849474428	2.32E-23
UVM	Epifactor	ZC3H15	CIR1	0.850886449	1.65E-23
UVM	Epifactor	ZC3H15	SMARCAD1	0.851192863	1.53E-23
UVM	Epifactor	ZC3H15	PCGF6	0.851240653	1.51E-23
UVM	Epifactor	ZC3H15	NBN	0.85432218	7.12E-24
UVM	Epifactor	ZC3H15	DDX21	0.856584231	4.05E-24
UVM	Epifactor	ZC3H15	OGT	0.859402957	1.97E-24
UVM	Epifactor	ZC3H15	CHUK	0.860162589	1.62E-24
UVM	Epifactor	ZC3H15	PHF14	0.860704668	1.41E-24
UVM	Epifactor	ZC3H15	ZMYM2	0.8625589	8.66E-25
UVM	Epifactor	ZC3H15	BRCA2	0.86311433	7.48E-25
UVM	Epifactor	ZC3H15	RMI1	0.864453944	5.23E-25
UVM	Epifactor	ZC3H15	HMGB1	0.86586519	3.58E-25
UVM	Epifactor	ZC3H15	NSL1	0.871289755	7.96E-26
UVM	Epifactor	ZC3H15	SIRT1	0.871909216	6.68E-26
UVM	Epifactor	ZC3H15	PARG	0.871953518	6.59E-26
UVM	Epifactor	ZC3H15	CDK17	0.873987329	3.68E-26
UVM	Epifactor	ZC3H15	ACTR6	0.874505951	3.16E-26
UVM	Epifactor	ZC3H15	DNTTIP2	0.874814514	2.89E-26
UVM	Epifactor	ZC3H15	USP15	0.877314649	1.38E-26
UVM	Epifactor	ZC3H15	BAZ2B	0.877564478	1.28E-26
UVM	Epifactor	ZC3H15	ARID4A	0.880078152	6.00E-27
UVM	Epifactor	ZC3H15	CLOCK	0.880810834	4.79E-27
UVM	Epifactor	ZC3H15	ATF2	0.880881636	4.69E-27
UVM	Epifactor	ZC3H15	SMARCA5	0.882152517	3.17E-27
UVM	Epifactor	ZC3H15	NIPBL	0.882298844	3.02E-27
UVM	Epifactor	ZC3H15	TDG	0.883280996	2.22E-27
UVM	Epifactor	ZC3H15	PRKAA1	0.884415376	1.55E-27
UVM	Epifactor	ZC3H15	INO80D	0.885448425	1.12E-27
UVM	Epifactor	ZC3H15	ZRANB3	0.888368716	4.32E-28
UVM	Epifactor	ZC3H15	YY1	0.89257975	1.05E-28
UVM	Epifactor	ZC3H15	PHF20L1	0.892748796	9.88E-29
UVM	Epifactor	ZC3H15	CHD1	0.893074002	8.83E-29
UVM	Epifactor	ZC3H15	CBX3	0.895801678	3.40E-29
UVM	Epifactor	ZC3H15	CUL5	0.896979287	2.23E-29
UVM	Epifactor	ZC3H15	YEATS4	0.898084472	1.50E-29
UVM	Epifactor	ZC3H15	EPC2	0.898592039	1.25E-29
UVM	Epifactor	ZC3H15	JMJD1C	0.899473184	9.01E-30
UVM	Epifactor	ZC3H15	ATAD2B	0.9000809	7.20E-30
UVM	Epifactor	ZC3H15	SMEK1	0.901561165	4.14E-30
UVM	Epifactor	ZC3H15	MASTL	0.901856431	3.70E-30
UVM	Epifactor	ZC3H15	CDC73	0.904833399	1.18E-30
UVM	Epifactor	ZC3H15	RLIM	0.90565512	8.55E-31
UVM	Epifactor	ZC3H15	AEBP2	0.905742933	8.26E-31
UVM	Epifactor	ZC3H15	BRCC3	0.906119103	7.12E-31
UVM	Epifactor	ZC3H15	ATM	0.907738771	3.73E-31
UVM	Epifactor	ZC3H15	HAT1	0.909473587	1.84E-31
UVM	Epifactor	ZC3H15	TAF7	0.910766545	1.08E-31
UVM	Epifactor	ZC3H15	UCHL5	0.912102571	6.13E-32
UVM	Epifactor	ZC3H15	BAZ1A	0.912962305	4.25E-32
UVM	Epifactor	ZC3H15	FAM175B	0.914882098	1.85E-32
UVM	Epifactor	ZC3H15	SUZ12	0.915247731	1.57E-32
UVM	Epifactor	ZC3H15	SF3B1	0.920246714	1.62E-33
UVM	Epifactor	ZC3H15	CUL3	0.931354942	5.77E-36
UVM	Epifactor	ZC3H15	CUL2	0.938418801	9.56E-38
UVM	Epifactor	ZC3H15	TLK1	0.939289291	5.58E-38
UVM	Epifactor	ZC3H15	SMEK2	0.946640822	4.18E-40
UVM	IUPHAR	ZC3H15	CLK4	0.80044112	5.14E-19
UVM	IUPHAR	ZC3H15	CASP8	0.801781427	4.06E-19
UVM	IUPHAR	ZC3H15	TAS2R14	0.801789003	4.05E-19
UVM	IUPHAR	ZC3H15	MAP2K4	0.802104016	3.84E-19
UVM	IUPHAR	ZC3H15	CYP2R1	0.802173432	3.79E-19
UVM	IUPHAR	ZC3H15	METAP2	0.802268084	3.73E-19
UVM	IUPHAR	ZC3H15	DYRK1A	0.803651825	2.91E-19
UVM	IUPHAR	ZC3H15	ATP11C	0.804030777	2.72E-19
UVM	IUPHAR	ZC3H15	RIOK1	0.80622487	1.84E-19
UVM	IUPHAR	ZC3H15	TMEM165	0.806778354	1.66E-19
UVM	IUPHAR	ZC3H15	SGPP1	0.807925779	1.35E-19
UVM	IUPHAR	ZC3H15	IL6ST	0.80842031	1.23E-19
UVM	IUPHAR	ZC3H15	PIP5K1A	0.809732957	9.67E-20
UVM	IUPHAR	ZC3H15	TRIM33	0.810072956	9.08E-20
UVM	IUPHAR	ZC3H15	UGCG	0.810129202	8.99E-20
UVM	IUPHAR	ZC3H15	PIK3CA	0.811480752	6.99E-20
UVM	IUPHAR	ZC3H15	ZMYND11	0.8120003	6.35E-20
UVM	IUPHAR	ZC3H15	TRIM24	0.815156291	3.50E-20
UVM	IUPHAR	ZC3H15	IRAK4	0.815773783	3.11E-20
UVM	IUPHAR	ZC3H15	TLK2	0.817243277	2.34E-20
UVM	IUPHAR	ZC3H15	YES1	0.817529973	2.22E-20
UVM	IUPHAR	ZC3H15	TAF1	0.81760543	2.18E-20
UVM	IUPHAR	ZC3H15	MFN1	0.81807264	1.99E-20
UVM	IUPHAR	ZC3H15	CLK1	0.818474773	1.84E-20
UVM	IUPHAR	ZC3H15	SLC26A2	0.818767876	1.74E-20
UVM	IUPHAR	ZC3H15	CDK8	0.819297192	1.57E-20
UVM	IUPHAR	ZC3H15	PHIP	0.82024836	1.30E-20
UVM	IUPHAR	ZC3H15	MARK3	0.820396086	1.27E-20
UVM	IUPHAR	ZC3H15	EZH2	0.823162233	7.31E-21
UVM	IUPHAR	ZC3H15	MTR	0.82523774	4.81E-21
UVM	IUPHAR	ZC3H15	SLC30A6	0.825670299	4.41E-21
UVM	IUPHAR	ZC3H15	PKN2	0.826000001	4.12E-21
UVM	IUPHAR	ZC3H15	VRK1	0.829909973	1.84E-21
UVM	IUPHAR	ZC3H15	SCYL2	0.830367092	1.67E-21
UVM	IUPHAR	ZC3H15	SPTLC1	0.830897788	1.49E-21
UVM	IUPHAR	ZC3H15	RPS6KC1	0.831555186	1.30E-21
UVM	IUPHAR	ZC3H15	SP100	0.832819062	9.94E-22
UVM	IUPHAR	ZC3H15	SLC35F5	0.833243693	9.08E-22
UVM	IUPHAR	ZC3H15	BIRC6	0.834072456	7.60E-22
UVM	IUPHAR	ZC3H15	SLC37A3	0.834711109	6.63E-22
UVM	IUPHAR	ZC3H15	ATP2B1	0.835767051	5.27E-22
UVM	IUPHAR	ZC3H15	ATP6V0A2	0.836193114	4.80E-22
UVM	IUPHAR	ZC3H15	SMG1	0.836954451	4.07E-22
UVM	IUPHAR	ZC3H15	STK3	0.836964047	4.06E-22
UVM	IUPHAR	ZC3H15	ITGAV	0.837913801	3.29E-22
UVM	IUPHAR	ZC3H15	EGLN1	0.83838298	2.97E-22
UVM	IUPHAR	ZC3H15	JAK2	0.838702719	2.77E-22
UVM	IUPHAR	ZC3H15	BRWD3	0.840729152	1.76E-22
UVM	IUPHAR	ZC3H15	BRWD1	0.841574043	1.45E-22
UVM	IUPHAR	ZC3H15	PI4K2B	0.841702499	1.41E-22
UVM	IUPHAR	ZC3H15	TAOK3	0.844610211	7.27E-23
UVM	IUPHAR	ZC3H15	IDE	0.84471463	7.10E-23
UVM	IUPHAR	ZC3H15	ATP6V1C1	0.844822232	6.92E-23
UVM	IUPHAR	ZC3H15	IDI1	0.847378386	3.81E-23
UVM	IUPHAR	ZC3H15	NR2C1	0.847631117	3.59E-23
UVM	IUPHAR	ZC3H15	NEK1	0.848361199	3.02E-23
UVM	IUPHAR	ZC3H15	HMGCS1	0.848746338	2.76E-23
UVM	IUPHAR	ZC3H15	NEK7	0.84971172	2.19E-23
UVM	IUPHAR	ZC3H15	HMGCR	0.850332221	1.89E-23
UVM	IUPHAR	ZC3H15	CSNK1A1	0.852861858	1.02E-23
UVM	IUPHAR	ZC3H15	PLA2G12A	0.853784676	8.13E-24
UVM	IUPHAR	ZC3H15	PIK3C2A	0.854089601	7.54E-24
UVM	IUPHAR	ZC3H15	STK38L	0.857328736	3.35E-24
UVM	IUPHAR	ZC3H15	SLC30A9	0.858955344	2.21E-24
UVM	IUPHAR	ZC3H15	MAGT1	0.85909768	2.13E-24
UVM	IUPHAR	ZC3H15	TOP1	0.859167619	2.10E-24
UVM	IUPHAR	ZC3H15	PLK4	0.859253146	2.05E-24
UVM	IUPHAR	ZC3H15	KRAS	0.859355482	2.00E-24
UVM	IUPHAR	ZC3H15	CHUK	0.860162589	1.62E-24
UVM	IUPHAR	ZC3H15	SLK	0.860369156	1.54E-24
UVM	IUPHAR	ZC3H15	SLC39A10	0.862264863	9.36E-25
UVM	IUPHAR	ZC3H15	ABCB10	0.863952641	5.98E-25
UVM	IUPHAR	ZC3H15	PIK3C3	0.866008301	3.44E-25
UVM	IUPHAR	ZC3H15	MAPK6	0.866235875	3.24E-25
UVM	IUPHAR	ZC3H15	TNKS2	0.866303147	3.18E-25
UVM	IUPHAR	ZC3H15	BMPR2	0.868324635	1.83E-25
UVM	IUPHAR	ZC3H15	STK17A	0.868814061	1.59E-25
UVM	IUPHAR	ZC3H15	PRPF4B	0.869248906	1.41E-25
UVM	IUPHAR	ZC3H15	NFE2L2	0.870886303	8.92E-26
UVM	IUPHAR	ZC3H15	HSP90AA1	0.871117861	8.36E-26
UVM	IUPHAR	ZC3H15	SIRT1	0.871909216	6.68E-26
UVM	IUPHAR	ZC3H15	RIOK2	0.873240756	4.56E-26
UVM	IUPHAR	ZC3H15	CDK17	0.873987329	3.68E-26
UVM	IUPHAR	ZC3H15	SLC25A46	0.874752702	2.94E-26
UVM	IUPHAR	ZC3H15	TRPM7	0.875579177	2.31E-26
UVM	IUPHAR	ZC3H15	PIKFYVE	0.875929677	2.08E-26
UVM	IUPHAR	ZC3H15	MAP3K2	0.877278307	1.40E-26
UVM	IUPHAR	ZC3H15	BAZ2B	0.877564478	1.28E-26
UVM	IUPHAR	ZC3H15	BIRC2	0.878139523	1.08E-26
UVM	IUPHAR	ZC3H15	BMPR1A	0.880450527	5.36E-27
UVM	IUPHAR	ZC3H15	CLOCK	0.880810834	4.79E-27
UVM	IUPHAR	ZC3H15	PRKAA1	0.884415376	1.55E-27
UVM	IUPHAR	ZC3H15	ADAM17	0.890545157	2.09E-28
UVM	IUPHAR	ZC3H15	NAPEPLD	0.891372198	1.58E-28
UVM	IUPHAR	ZC3H15	XIAP	0.892888469	9.42E-29
UVM	IUPHAR	ZC3H15	RIOK3	0.892952171	9.21E-29
UVM	IUPHAR	ZC3H15	SLC30A5	0.893433051	7.80E-29
UVM	IUPHAR	ZC3H15	TBK1	0.896567129	2.59E-29
UVM	IUPHAR	ZC3H15	JMJD1C	0.899473184	9.01E-30
UVM	IUPHAR	ZC3H15	ATAD2B	0.9000809	7.20E-30
UVM	IUPHAR	ZC3H15	PSMD14	0.90141241	4.38E-30
UVM	IUPHAR	ZC3H15	MASTL	0.901856431	3.70E-30
UVM	IUPHAR	ZC3H15	CSNK1G3	0.902833026	2.56E-30
UVM	IUPHAR	ZC3H15	MAP4K3	0.905210092	1.02E-30
UVM	IUPHAR	ZC3H15	ATM	0.907738771	3.73E-31
UVM	IUPHAR	ZC3H15	PPAT	0.909227543	2.03E-31
UVM	IUPHAR	ZC3H15	HAT1	0.909473587	1.84E-31
UVM	IUPHAR	ZC3H15	USP14	0.911074048	9.46E-32
UVM	IUPHAR	ZC3H15	FBXO11	0.911124918	9.26E-32
UVM	IUPHAR	ZC3H15	BAZ1A	0.912962305	4.25E-32
UVM	IUPHAR	ZC3H15	VRK2	0.916762898	8.01E-33
UVM	IUPHAR	ZC3H15	PRMT3	0.926363128	8.10E-35
UVM	IUPHAR	ZC3H15	TLK1	0.939289291	5.58E-38
UVM	IUPHAR	ZC3H15	XPO1	0.940145258	3.26E-38
UVM	Kinase	ZC3H15	CLK4	0.80044112	5.14E-19
UVM	Kinase	ZC3H15	MAP2K4	0.802104016	3.84E-19
UVM	Kinase	ZC3H15	DYRK1A	0.803651825	2.91E-19
UVM	Kinase	ZC3H15	RIOK1	0.80622487	1.84E-19
UVM	Kinase	ZC3H15	TRIM33	0.810072956	9.08E-20
UVM	Kinase	ZC3H15	PAN3	0.811387827	7.11E-20
UVM	Kinase	ZC3H15	TRIM24	0.815156291	3.50E-20
UVM	Kinase	ZC3H15	IRAK4	0.815773783	3.11E-20
UVM	Kinase	ZC3H15	TLK2	0.817243277	2.34E-20
UVM	Kinase	ZC3H15	YES1	0.817529973	2.22E-20
UVM	Kinase	ZC3H15	TAF1	0.81760543	2.18E-20
UVM	Kinase	ZC3H15	CLK1	0.818474773	1.84E-20
UVM	Kinase	ZC3H15	CDK8	0.819297192	1.57E-20
UVM	Kinase	ZC3H15	MARK3	0.820396086	1.27E-20
UVM	Kinase	ZC3H15	PKN2	0.826000001	4.12E-21
UVM	Kinase	ZC3H15	VRK1	0.829909973	1.84E-21
UVM	Kinase	ZC3H15	SCYL2	0.830367092	1.67E-21
UVM	Kinase	ZC3H15	RPS6KC1	0.831555186	1.30E-21
UVM	Kinase	ZC3H15	SMG1	0.836954451	4.07E-22
UVM	Kinase	ZC3H15	STK3	0.836964047	4.06E-22
UVM	Kinase	ZC3H15	JAK2	0.838702719	2.77E-22
UVM	Kinase	ZC3H15	COL4A3BP	0.83899491	2.59E-22
UVM	Kinase	ZC3H15	TAOK3	0.844610211	7.27E-23
UVM	Kinase	ZC3H15	NEK1	0.848361199	3.02E-23
UVM	Kinase	ZC3H15	NEK7	0.84971172	2.19E-23
UVM	Kinase	ZC3H15	CSNK1A1	0.852861858	1.02E-23
UVM	Kinase	ZC3H15	STK38L	0.857328736	3.35E-24
UVM	Kinase	ZC3H15	PLK4	0.859253146	2.05E-24
UVM	Kinase	ZC3H15	CHUK	0.860162589	1.62E-24
UVM	Kinase	ZC3H15	SLK	0.860369156	1.54E-24
UVM	Kinase	ZC3H15	MAPK6	0.866235875	3.24E-25
UVM	Kinase	ZC3H15	BMPR2	0.868324635	1.83E-25
UVM	Kinase	ZC3H15	STK17A	0.868814061	1.59E-25
UVM	Kinase	ZC3H15	PRPF4B	0.869248906	1.41E-25
UVM	Kinase	ZC3H15	RIOK2	0.873240756	4.56E-26
UVM	Kinase	ZC3H15	CDK17	0.873987329	3.68E-26
UVM	Kinase	ZC3H15	TRPM7	0.875579177	2.31E-26
UVM	Kinase	ZC3H15	MAP3K2	0.877278307	1.40E-26
UVM	Kinase	ZC3H15	BMPR1A	0.880450527	5.36E-27
UVM	Kinase	ZC3H15	PRKAA1	0.884415376	1.55E-27
UVM	Kinase	ZC3H15	RIOK3	0.892952171	9.21E-29
UVM	Kinase	ZC3H15	TBK1	0.896567129	2.59E-29
UVM	Kinase	ZC3H15	MASTL	0.901856431	3.70E-30
UVM	Kinase	ZC3H15	CSNK1G3	0.902833026	2.56E-30
UVM	Kinase	ZC3H15	MAP4K3	0.905210092	1.02E-30
UVM	Kinase	ZC3H15	ATM	0.907738771	3.73E-31
UVM	Kinase	ZC3H15	BAZ1A	0.912962305	4.25E-32
UVM	Kinase	ZC3H15	VRK2	0.916762898	8.01E-33
UVM	Kinase	ZC3H15	TLK1	0.939289291	5.58E-38
UVM	TF	ZC3H15	RLF	0.80042545	5.15E-19
UVM	TF	ZC3H15	ZNF614	0.800538588	5.05E-19
UVM	TF	ZC3H15	TCF12	0.800830313	4.80E-19
UVM	TF	ZC3H15	ZNF606	0.800976338	4.68E-19
UVM	TF	ZC3H15	E2F5	0.801985461	3.92E-19
UVM	TF	ZC3H15	ZNF625	0.803187077	3.17E-19
UVM	TF	ZC3H15	ZNF624	0.803571819	2.96E-19
UVM	TF	ZC3H15	ZNF823	0.803584627	2.95E-19
UVM	TF	ZC3H15	MGA	0.803794628	2.84E-19
UVM	TF	ZC3H15	ZNF273	0.804010713	2.73E-19
UVM	TF	ZC3H15	ZNF160	0.804013951	2.73E-19
UVM	TF	ZC3H15	ZNF81	0.804863478	2.35E-19
UVM	TF	ZC3H15	ZKSCAN5	0.805274866	2.18E-19
UVM	TF	ZC3H15	ZNF558	0.806076709	1.89E-19
UVM	TF	ZC3H15	ZNF611	0.807102632	1.57E-19
UVM	TF	ZC3H15	ZNF569	0.807229454	1.53E-19
UVM	TF	ZC3H15	ZNF485	0.809119085	1.08E-19
UVM	TF	ZC3H15	ZNF562	0.809266812	1.05E-19
UVM	TF	ZC3H15	CDC5L	0.809407819	1.03E-19
UVM	TF	ZC3H15	HIF1A	0.810187974	8.89E-20
UVM	TF	ZC3H15	ZNF100	0.811397199	7.10E-20
UVM	TF	ZC3H15	ZNF782	0.811660316	6.76E-20
UVM	TF	ZC3H15	TTF1	0.812873689	5.39E-20
UVM	TF	ZC3H15	ZBTB11	0.813811151	4.51E-20
UVM	TF	ZC3H15	ZNF200	0.814092835	4.28E-20
UVM	TF	ZC3H15	ZNF10	0.814267673	4.14E-20
UVM	TF	ZC3H15	VEZF1	0.814295	4.12E-20
UVM	TF	ZC3H15	ZNF461	0.815298969	3.40E-20
UVM	TF	ZC3H15	TET2	0.815539274	3.25E-20
UVM	TF	ZC3H15	ZNF678	0.815819623	3.08E-20
UVM	TF	ZC3H15	ZNF227	0.816448137	2.73E-20
UVM	TF	ZC3H15	ZNF83	0.819024402	1.66E-20
UVM	TF	ZC3H15	ZBED5	0.820121456	1.34E-20
UVM	TF	ZC3H15	ZNF141	0.820198781	1.32E-20
UVM	TF	ZC3H15	ZNF223	0.82071912	1.19E-20
UVM	TF	ZC3H15	ZNF235	0.82076887	1.18E-20
UVM	TF	ZC3H15	ZNF148	0.821005054	1.12E-20
UVM	TF	ZC3H15	ZNF780B	0.821111865	1.10E-20
UVM	TF	ZC3H15	ZNF248	0.821843232	9.51E-21
UVM	TF	ZC3H15	ZNF44	0.822662751	8.08E-21
UVM	TF	ZC3H15	ZNF808	0.824072994	6.09E-21
UVM	TF	ZC3H15	ZFP14	0.824310526	5.81E-21
UVM	TF	ZC3H15	ZNF354B	0.82443131	5.67E-21
UVM	TF	ZC3H15	ZNF557	0.82465693	5.41E-21
UVM	TF	ZC3H15	SP4	0.826566595	3.67E-21
UVM	TF	ZC3H15	ZNF253	0.827156915	3.25E-21
UVM	TF	ZC3H15	ZNF470	0.828267064	2.59E-21
UVM	TF	ZC3H15	ZNF480	0.828305012	2.57E-21
UVM	TF	ZC3H15	ZNF107	0.828722829	2.35E-21
UVM	TF	ZC3H15	ZNF225	0.828785773	2.32E-21
UVM	TF	ZC3H15	ZNF347	0.830177264	1.74E-21
UVM	TF	ZC3H15	MYNN	0.830963146	1.47E-21
UVM	TF	ZC3H15	SP100	0.832819062	9.94E-22
UVM	TF	ZC3H15	ZNF222	0.833361846	8.86E-22
UVM	TF	ZC3H15	SMAD4	0.833465279	8.66E-22
UVM	TF	ZC3H15	ZNF14	0.834882875	6.39E-22
UVM	TF	ZC3H15	ZNF25	0.835495309	5.59E-22
UVM	TF	ZC3H15	ELK3	0.835725949	5.32E-22
UVM	TF	ZC3H15	ZNF674	0.836716393	4.29E-22
UVM	TF	ZC3H15	ZNF600	0.837516338	3.60E-22
UVM	TF	ZC3H15	ZNF143	0.838501115	2.89E-22
UVM	TF	ZC3H15	ZNF585B	0.839974649	2.08E-22
UVM	TF	ZC3H15	ZNF420	0.840095386	2.03E-22
UVM	TF	ZC3H15	ZNF555	0.840335489	1.92E-22
UVM	TF	ZC3H15	ZNF281	0.841021666	1.65E-22
UVM	TF	ZC3H15	ZFX	0.842667599	1.14E-22
UVM	TF	ZC3H15	TMF1	0.843464836	9.46E-23
UVM	TF	ZC3H15	ZNF658	0.843532041	9.32E-23
UVM	TF	ZC3H15	ATF1	0.845476613	5.95E-23
UVM	TF	ZC3H15	ZBTB33	0.845765679	5.56E-23
UVM	TF	ZC3H15	ZNF226	0.846580238	4.60E-23
UVM	TF	ZC3H15	ZNF320	0.846798687	4.37E-23
UVM	TF	ZC3H15	ZNF326	0.847061943	4.11E-23
UVM	TF	ZC3H15	ZNF708	0.847615832	3.60E-23
UVM	TF	ZC3H15	NR2C1	0.847631117	3.59E-23
UVM	TF	ZC3H15	ADNP2	0.847749519	3.49E-23
UVM	TF	ZC3H15	GABPA	0.847898596	3.37E-23
UVM	TF	ZC3H15	ZNF572	0.848024891	3.27E-23
UVM	TF	ZC3H15	ARID2	0.849133248	2.51E-23
UVM	TF	ZC3H15	ZNF84	0.849218323	2.46E-23
UVM	TF	ZC3H15	ZNF280C	0.849562614	2.27E-23
UVM	TF	ZC3H15	ZNF12	0.85000544	2.04E-23
UVM	TF	ZC3H15	MYBL1	0.850632654	1.75E-23
UVM	TF	ZC3H15	PCGF6	0.851240653	1.51E-23
UVM	TF	ZC3H15	ZNF680	0.851723557	1.35E-23
UVM	TF	ZC3H15	ZNF700	0.851853257	1.31E-23
UVM	TF	ZC3H15	ZNF440	0.852207705	1.20E-23
UVM	TF	ZC3H15	JRKL	0.854126744	7.47E-24
UVM	TF	ZC3H15	ZNF302	0.854363608	7.05E-24
UVM	TF	ZC3H15	ZNF37A	0.855924193	4.78E-24
UVM	TF	ZC3H15	ZNF45	0.856230214	4.42E-24
UVM	TF	ZC3H15	ZNF566	0.85704072	3.60E-24
UVM	TF	ZC3H15	THAP9	0.857145826	3.51E-24
UVM	TF	ZC3H15	ZNF761	0.858426127	2.53E-24
UVM	TF	ZC3H15	ZNF546	0.858797865	2.30E-24
UVM	TF	ZC3H15	ZNF26	0.859314574	2.02E-24
UVM	TF	ZC3H15	HDX	0.859533039	1.91E-24
UVM	TF	ZC3H15	ZNF567	0.859641732	1.85E-24
UVM	TF	ZC3H15	ZNF260	0.860051951	1.67E-24
UVM	TF	ZC3H15	ZNF41	0.860622002	1.44E-24
UVM	TF	ZC3H15	ZBTB41	0.860899047	1.34E-24
UVM	TF	ZC3H15	ZNF449	0.863000112	7.71E-25
UVM	TF	ZC3H15	ZNF518A	0.863318122	7.09E-25
UVM	TF	ZC3H15	ZNF845	0.864309116	5.44E-25
UVM	TF	ZC3H15	DMTF1	0.864390142	5.32E-25
UVM	TF	ZC3H15	ZNF280D	0.865278753	4.19E-25
UVM	TF	ZC3H15	ZNF484	0.865683404	3.76E-25
UVM	TF	ZC3H15	ZNF432	0.866227725	3.24E-25
UVM	TF	ZC3H15	BACH1	0.866865208	2.73E-25
UVM	TF	ZC3H15	NFXL1	0.867184778	2.50E-25
UVM	TF	ZC3H15	ZNF451	0.86798765	2.00E-25
UVM	TF	ZC3H15	ELF2	0.868016235	1.99E-25
UVM	TF	ZC3H15	ZNF138	0.868364399	1.81E-25
UVM	TF	ZC3H15	ZNF234	0.869575696	1.29E-25
UVM	TF	ZC3H15	ZNF268	0.86971088	1.24E-25
UVM	TF	ZC3H15	ZNF75D	0.87087953	8.94E-26
UVM	TF	ZC3H15	NFE2L2	0.870886303	8.92E-26
UVM	TF	ZC3H15	ZNF92	0.871329594	7.87E-26
UVM	TF	ZC3H15	ZNF180	0.871502804	7.50E-26
UVM	TF	ZC3H15	PRDM10	0.871706421	7.07E-26
UVM	TF	ZC3H15	ZNF721	0.872424279	5.77E-26
UVM	TF	ZC3H15	ZNF254	0.872718228	5.30E-26
UVM	TF	ZC3H15	ZNF383	0.872922534	5.00E-26
UVM	TF	ZC3H15	ZNF441	0.873022602	4.86E-26
UVM	TF	ZC3H15	TERF1	0.873467165	4.27E-26
UVM	TF	ZC3H15	ZNF24	0.873892758	3.78E-26
UVM	TF	ZC3H15	ZNF397	0.874365633	3.29E-26
UVM	TF	ZC3H15	ELF1	0.874802165	2.90E-26
UVM	TF	ZC3H15	BAZ2B	0.877564478	1.28E-26
UVM	TF	ZC3H15	CREBZF	0.879218524	7.80E-27
UVM	TF	ZC3H15	ZNF527	0.880177624	5.82E-27
UVM	TF	ZC3H15	THAP6	0.880518259	5.25E-27
UVM	TF	ZC3H15	CLOCK	0.880810834	4.79E-27
UVM	TF	ZC3H15	ATF2	0.880881636	4.69E-27
UVM	TF	ZC3H15	LIN54	0.881071811	4.42E-27
UVM	TF	ZC3H15	FOXN2	0.881126112	4.35E-27
UVM	TF	ZC3H15	PURB	0.881301079	4.12E-27
UVM	TF	ZC3H15	ZNF468	0.881488411	3.89E-27
UVM	TF	ZC3H15	ZNF431	0.882082398	3.24E-27
UVM	TF	ZC3H15	RBAK	0.883423829	2.13E-27
UVM	TF	ZC3H15	ZNF780A	0.884176717	1.68E-27
UVM	TF	ZC3H15	ZNF701	0.88430171	1.61E-27
UVM	TF	ZC3H15	ZBTB6	0.884776939	1.38E-27
UVM	TF	ZC3H15	ZNF510	0.88534992	1.15E-27
UVM	TF	ZC3H15	ZNF136	0.88587663	9.73E-28
UVM	TF	ZC3H15	MEF2A	0.887006322	6.75E-28
UVM	TF	ZC3H15	ZNF182	0.88725518	6.23E-28
UVM	TF	ZC3H15	ZNF140	0.89013119	2.40E-28
UVM	TF	ZC3H15	IKZF5	0.890287208	2.28E-28
UVM	TF	ZC3H15	ZC3H8	0.890538237	2.10E-28
UVM	TF	ZC3H15	SMAD5	0.891001961	1.79E-28
UVM	TF	ZC3H15	YY1	0.89257975	1.05E-28
UVM	TF	ZC3H15	ZNF430	0.893242955	8.33E-29
UVM	TF	ZC3H15	ZNF146	0.893952079	6.51E-29
UVM	TF	ZC3H15	ZNF195	0.894363144	5.64E-29
UVM	TF	ZC3H15	ZNF267	0.895395734	3.93E-29
UVM	TF	ZC3H15	ZNF791	0.895649662	3.59E-29
UVM	TF	ZC3H15	ZNF33A	0.897312421	1.98E-29
UVM	TF	ZC3H15	SP3	0.900028957	7.34E-30
UVM	TF	ZC3H15	TOPORS	0.901199977	4.74E-30
UVM	TF	ZC3H15	ZNF181	0.901255058	4.65E-30
UVM	TF	ZC3H15	AHCTF1	0.901643563	4.01E-30
UVM	TF	ZC3H15	AEBP2	0.905742933	8.26E-31
UVM	TF	ZC3H15	ZNF43	0.906812119	5.41E-31
UVM	TF	ZC3H15	ZBTB1	0.908052063	3.28E-31
UVM	TF	ZC3H15	ZNF800	0.909468136	1.84E-31
UVM	TF	ZC3H15	GPBP1	0.910587681	1.16E-31
UVM	TF	ZC3H15	CREB1	0.911136983	9.21E-32
UVM	TF	ZC3H15	THAP5	0.911536097	7.79E-32
UVM	TF	ZC3H15	ZNF131	0.91206292	6.23E-32
UVM	TF	ZC3H15	ZNF675	0.916301806	9.85E-33
UVM	TF	ZC3H15	ZNF28	0.918800107	3.17E-33
UVM	TF	ZC3H15	PRMT3	0.926363128	8.10E-35
UVM	TF	ZC3H15	CEBPZ	0.969549852	2.03E-49
UVM	TSG	ZC3H15	CASP8	0.801781427	4.06E-19
UVM	TSG	ZC3H15	MAP2K4	0.802104016	3.84E-19
UVM	TSG	ZC3H15	USP33	0.802752107	3.42E-19
UVM	TSG	ZC3H15	HIF1A	0.810187974	8.89E-20
UVM	TSG	ZC3H15	PAWR	0.811525751	6.93E-20
UVM	TSG	ZC3H15	PAFAH1B1	0.81178663	6.60E-20
UVM	TSG	ZC3H15	ZMYND11	0.8120003	6.35E-20
UVM	TSG	ZC3H15	TTF1	0.812873689	5.39E-20
UVM	TSG	ZC3H15	TRIM24	0.815156291	3.50E-20
UVM	TSG	ZC3H15	TET2	0.815539274	3.25E-20
UVM	TSG	ZC3H15	IFT88	0.820257774	1.30E-20
UVM	TSG	ZC3H15	EZH2	0.823162233	7.31E-21
UVM	TSG	ZC3H15	SDHD	0.824625186	5.45E-21
UVM	TSG	ZC3H15	PALB2	0.82569447	4.39E-21
UVM	TSG	ZC3H15	APC	0.826222377	3.94E-21
UVM	TSG	ZC3H15	COPS2	0.828633487	2.40E-21
UVM	TSG	ZC3H15	SP100	0.832819062	9.94E-22
UVM	TSG	ZC3H15	SMAD4	0.833465279	8.66E-22
UVM	TSG	ZC3H15	ITGAV	0.837913801	3.29E-22
UVM	TSG	ZC3H15	EGLN1	0.83838298	2.97E-22
UVM	TSG	ZC3H15	DICER1	0.840456424	1.87E-22
UVM	TSG	ZC3H15	NEDD4	0.843684517	9.00E-23
UVM	TSG	ZC3H15	UHRF2	0.845750482	5.58E-23
UVM	TSG	ZC3H15	PHF6	0.845890547	5.40E-23
UVM	TSG	ZC3H15	ARID2	0.849133248	2.51E-23
UVM	TSG	ZC3H15	CSNK1A1	0.852861858	1.02E-23
UVM	TSG	ZC3H15	TANK	0.853357711	9.03E-24
UVM	TSG	ZC3H15	NBN	0.85432218	7.12E-24
UVM	TSG	ZC3H15	PTPN12	0.857057353	3.59E-24
UVM	TSG	ZC3H15	PPM1A	0.859176919	2.09E-24
UVM	TSG	ZC3H15	CHUK	0.860162589	1.62E-24
UVM	TSG	ZC3H15	FAM188A	0.860376	1.53E-24
UVM	TSG	ZC3H15	PDS5B	0.862803731	8.12E-25
UVM	TSG	ZC3H15	BRCA2	0.86311433	7.48E-25
UVM	TSG	ZC3H15	PTPN2	0.863416403	6.90E-25
UVM	TSG	ZC3H15	DMTF1	0.864390142	5.32E-25
UVM	TSG	ZC3H15	APAF1	0.867333802	2.40E-25
UVM	TSG	ZC3H15	BMPR2	0.868324635	1.83E-25
UVM	TSG	ZC3H15	ANXA7	0.868384148	1.80E-25
UVM	TSG	ZC3H15	RB1CC1	0.869102076	1.47E-25
UVM	TSG	ZC3H15	MLH3	0.869726869	1.24E-25
UVM	TSG	ZC3H15	SIRT1	0.871909216	6.68E-26
UVM	TSG	ZC3H15	WDR11	0.872054138	6.41E-26
UVM	TSG	ZC3H15	DCLRE1A	0.87519557	2.59E-26
UVM	TSG	ZC3H15	RBBP8	0.875336187	2.48E-26
UVM	TSG	ZC3H15	BMPR1A	0.880450527	5.36E-27
UVM	TSG	ZC3H15	GORAB	0.883165729	2.31E-27
UVM	TSG	ZC3H15	PRKAA1	0.884415376	1.55E-27
UVM	TSG	ZC3H15	VEZT	0.889407274	3.06E-28
UVM	TSG	ZC3H15	CCAR1	0.889717655	2.76E-28
UVM	TSG	ZC3H15	MSH2	0.890946687	1.83E-28
UVM	TSG	ZC3H15	NAPEPLD	0.891372198	1.58E-28
UVM	TSG	ZC3H15	CHD1	0.893074002	8.83E-29
UVM	TSG	ZC3H15	KRIT1	0.89614046	3.01E-29
UVM	TSG	ZC3H15	CUL5	0.896979287	2.23E-29
UVM	TSG	ZC3H15	LIN9	0.898871085	1.12E-29
UVM	TSG	ZC3H15	GTPBP4	0.898903305	1.11E-29
UVM	TSG	ZC3H15	GGNBP2	0.899470671	9.02E-30
UVM	TSG	ZC3H15	TOPORS	0.901199977	4.74E-30
UVM	TSG	ZC3H15	CDC73	0.904833399	1.18E-30
UVM	TSG	ZC3H15	RINT1	0.906040865	7.34E-31
UVM	TSG	ZC3H15	INTS6	0.907003037	5.01E-31
UVM	TSG	ZC3H15	ATM	0.907738771	3.73E-31
UVM	TSG	ZC3H15	SUZ12	0.915247731	1.57E-32
UVM	TSG	ZC3H15	SMCHD1	0.919071334	2.80E-33
UVM	TSG	ZC3H15	CUL2	0.938418801	9.56E-38

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LUAD	ZC3H15	DRG1	-1.38896782665224	0.00022838170846318
KICH	ZC3H15	NAP1L2	-1.37359505003666	0.000287055969238281
ESCA	ZC3H15	SSB	-1.23796441345986	0.0009765625
KIRP	ZC3H15	METAP2	1.2125553034505	0.00166679499670863
KICH	ZC3H15	MORF4L2	1.12375683675494	0.00378090143203735
BLCA	ZC3H15	SSB	-1.65629492626017	0.00532913208007812
ESCA	ZC3H15	RWDD1	1.43074573953025	0.009765625
STAD	ZC3H15	MORF4L2	-1.07938857268274	0.0105091729201376
KIRC	ZC3H15	DRG1	-4.16008421708878	0.0152218459760014
UCEC	ZC3H15	SSB	1.65253824162666	0.015625
CHOL	ZC3H15	DRG1	-2.74036943476079	0.01953125
PRAD	ZC3H15	RWDD1	-1.37015889011473	0.0291755363147523
KIRP	ZC3H15	NAP1L2	-1.36163321869008	1.72760337591171e-07
LUAD	ZC3H15	SSB	-2.61277287663291	2.13281101437522e-07
KIRC	ZC3H15	MORF4L2	-1.05370934327216	3.09053485681633e-05
BRCA	ZC3H15	RWDD1	-1.13785288766259	3.18183978181012e-05
KICH	ZC3H15	SSB	2.64570519946507	3.814697265625e-05
HNSC	ZC3H15	SSB	-1.89332784154116	4.83197595713137e-06
LIHC	ZC3H15	SSB	-1.12588524134019	5.45859083813367e-05
BRCA	ZC3H15	DRG2	1.55172876221269	5.83844264602967e-05

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with ZC3H15

TNNT1, C8orf33, DRG1, ISG15, THOC1, THOC3, THOC5, THOC2, THOC6, THOC7, WASF1, UTRN, PPIP5K1, TSSK2, ZCCHC8, PPIP5K2, CSNK2A1, PARK2, PHKG2, STAU1, TRAF2, RNF2, ABCF2, FAF1, GINS3, HMGN5, WDR74, NTRK1, KRAS, MED4, CC2D2A, CEP44, DCTN1, CEP19, CETN2, XPO1, TM9SF4, MRPL50, Fbxo21, CDH1, NCL, MTF1, BRD1, EFTUD2, ESR2, HEXIM1, RECQL4, EZR, AGRN, PTEN, SNRNP70, Dppa3, BIRC3, NFX1, BRD7, PLEKHA4, ESR1, LRRC59, INS, Apc2, nsp10, IFI16, DNAJC2, DNAJC1, OGT, UFL1, DDRGK1, EIF6, FBL, RPS20, RPS24, TRIM36, FZR1, WDR5, NAA40, E, M, ORF6, ORF7a, SQSTM1, N,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
ZC3H15	LIHC	chr2	187365006	187365006	A	-	Frame_Shift_Del	p.Q92fs	5
ZC3H15	UCEC	chr2	187373395	187373395	C	A	Missense_Mutation	p.L406I	4
ZC3H15	BRCA	chr2	187351168	187351170	AGG	-	In_Frame_Del	p.E21in_frame_del	4
ZC3H15	BRCA	chr2	187370515	187370515	G	A	Missense_Mutation	p.D305N	4
ZC3H15	PAAD	chr2	187370558	187370558	G	T	Missense_Mutation	p.G319V	4
ZC3H15	ACC	chr2	187373328	187373328	G	T	Missense_Mutation	p.L383F	3
ZC3H15	ESCA	chr2	187370271	187370271	G	C	Missense_Mutation	p.E271Q	3
ZC3H15	UCEC	chr2	187371444	187371444	A	C	Missense_Mutation	p.D324A	3
ZC3H15	PAAD	chr2	187370558	187370558	G	T	Missense_Mutation		3
ZC3H15	SKCM	chr2	187370268	187370268	C	T	Missense_Mutation	p.L270F	3
ZC3H15	PAAD	chr2	187370212	187370212	C	T	Missense_Mutation	p.T251I	3
ZC3H15	SKCM	chr2	187370494	187370494	C	T	Missense_Mutation	p.R298C	3
ZC3H15	BRCA	chr2	187371487	187371487	C	T	Silent	p.I338	3
ZC3H15	SARC	chr2	187370520	187370520	T	C	Silent		2
ZC3H15	ESCA	chr2	187370557	187370557	G	T	Missense_Mutation	p.G319C	2
ZC3H15	SARC	chr2	187368861	187368861	C	T	Missense_Mutation		2
ZC3H15	LIHC	chr2	187351141	187351141	G	A	Missense_Mutation		2
ZC3H15	LUAD	chr2	187371499	187371499	A	G	Silent	p.V342V	2
ZC3H15	SARC	chr2	187368862	187368862	C	T	Missense_Mutation		2
ZC3H15	CHOL	chr2	187351163	187351163	A	G	Silent		2
ZC3H15	STAD	chr2	187360023	187360023	A	G	Missense_Mutation	p.T47A	2
ZC3H15	SARC	chr2	187368861	187368861	C	T	Missense_Mutation	p.P213S	2
ZC3H15	BLCA	chr2	187371546	187371546	A	G	Missense_Mutation	p.Y358C	2
ZC3H15	HNSC	chr2	187366146	187366146	G	C	Missense_Mutation	p.E146Q	2
ZC3H15	CHOL	chr2	187351163	187351163	A	G	Silent	p.K18K	2
ZC3H15	LIHC	chr2	187351141	187351141	G	A	Missense_Mutation	p.G11D	2
ZC3H15	STAD	chr2	187373387	187373387	A	G	Missense_Mutation	p.D403G	2
ZC3H15	PAAD	chr2	187370212	187370212	C	T	Missense_Mutation		2
ZC3H15	UCEC	chr2	187364956	187364956	G	T	Missense_Mutation	p.K75N	2
ZC3H15	SARC	chr2	187368862	187368862	C	T	Missense_Mutation	p.P213L	2
ZC3H15	HNSC	chr2	187364950	187364950	C	G	Missense_Mutation	p.D73E	2
ZC3H15	ESCA	chr2	187370271	187370271	G	C	Missense_Mutation		2
ZC3H15	UCEC	chr2	187373361	187373361	T	C	Silent	p.N394	2
ZC3H15	BRCA	chr2	187370543	187370543	A	G	Missense_Mutation	p.Y314C	2
ZC3H15	LIHC	chr2	187359974	187359974	T	-	Frame_Shift_Del	p.G30fs	2
ZC3H15	LGG	chr2	187371527	187371527	C	G	Missense_Mutation	p.L352V	2
ZC3H15	LIHC	chr2	187360035	187360035	A	-	Frame_Shift_Del	p.K51fs	2
ZC3H15	LGG	chr2	187371527	187371527	C	G	Missense_Mutation		2
ZC3H15	LIHC	chr2	187364928	187364928	A	-	Frame_Shift_Del	p.E66fs	2
ZC3H15	ESCA	chr2	187359986	187359986	G	T	Missense_Mutation	p.K34N	2
ZC3H15	CESC	chr2	187351166	187351166	G	C	Missense_Mutation		2
ZC3H15	HNSC	chr2	187366146	187366146	G	C	Missense_Mutation		1
ZC3H15	CESC	chr2	187373329	187373329	G	T	Nonsense_Mutation		1
ZC3H15	LIHC	chr2	187366083	187366083	T	C	Silent		1
ZC3H15	STAD	chr2	187366110	187366110	C	T	Nonsense_Mutation	p.R134X	1
ZC3H15	LIHC	chr2	187351137	187351137	G	-	Frame_Shift_Del	p.G11fs	1
ZC3H15	THCA	chr2	187351112	187351113	-	C	Translation_Start_Site		1
ZC3H15	SARC	chr2	187364908	187364908	G	T	Splice_Site		1
ZC3H15	BLCA	chr2	187371546	187371546	A	G	Missense_Mutation		1
ZC3H15	HNSC	chr2	187368804	187368805	-	-	Frame_Shift_Ins		1
ZC3H15	CESC	chr2	187351166	187351166	G	C	Missense_Mutation	p.K19N	1
ZC3H15	LIHC	chr2	187371443	187371443	G	T	Missense_Mutation		1
ZC3H15	STAD	chr2	187364917	187364917	G	T	Missense_Mutation	p.Q62H	1
ZC3H15	ESCA	chr2	187370557	187370557	G	T	Missense_Mutation		1
ZC3H15	LUAD	chr2	187366001	187366001	T	G	Splice_Site	p.G97_splice	1
ZC3H15	THCA	chr2	187351145	187351145	C	-	Frame_Shift_Del	p.S12fs	1
ZC3H15	BLCA	chr2	187364925	187364925	C	A	Missense_Mutation		1
ZC3H15	HNSC	chr2	187359982	187359982	A	G	Missense_Mutation		1
ZC3H15	CESC	chr2	187373329	187373329	G	T	Nonsense_Mutation	p.E384*	1
ZC3H15	STAD	chr2	187368932	187368933	-	GA	Frame_Shift_Ins	p.I236fs	1
ZC3H15	ESCA	chr2	187359986	187359986	G	T	Missense_Mutation		1
ZC3H15	THYM	chr2	187368773	187368773	C	A	Missense_Mutation	p.F183L	1
ZC3H15	BLCA	chr2	187370514	187370514	T	A	Missense_Mutation		1
ZC3H15	HNSC	chr2	187370222	187370222	T	A	Silent	p.S254S	1
ZC3H15	LIHC	chr2	187366137	187366137	G	A	Missense_Mutation	p.E143K	1
ZC3H15	LUAD	chr2	187370495	187370495	G	A	Missense_Mutation	p.R298H	1
ZC3H15	ESCA	chr2	187359994	187359994	C	T	Missense_Mutation	p.A37V	1
ZC3H15	LUAD	chr2	187366001	187366001	T	G	Silent	p.G97G	1
ZC3H15	BLCA	chr2	187364925	187364925	C	A	Missense_Mutation	p.A65D	1
ZC3H15	COAD	chr2	187351164	187351166	AAG	-	In_Frame_Del	p.18_19del	1
ZC3H15	LIHC	chr2	187368804	187368805	-	G	Frame_Shift_Ins	p.V194fs	1
ZC3H15	STAD	chr2	187370510	187370512	ATG	-	In_Frame_Del	p.303_303del	1
ZC3H15	LUSC	chr2	187368929	187368929	A	G	Silent	p.L235L	1
ZC3H15	PAAD	chr2	187370582	187370582	T	G	Missense_Mutation		1
ZC3H15	SARC	chr2	187370520	187370520	T	C	Silent	p.D306D	1
ZC3H15	HNSC	chr2	187359982	187359982	A	G	Missense_Mutation	p.N33S	1
ZC3H15	COAD	chr2	187368789	187368791	AAC	-	In_Frame_Del	p.188_189del	1
ZC3H15	STAD	chr2	187366110	187366110	C	T	Nonsense_Mutation	p.R134*	1
ZC3H15	GBM	chr2	187368763	187368763	G	A	Missense_Mutation	p.C180Y	1
ZC3H15	LUSC	chr2	187368899	187368899	G	A	Silent	p.E225E	1
ZC3H15	PAAD	chr2	187364986	187364986	C	A	Missense_Mutation		1
ZC3H15	SARC	chr2	187370520	187370520	T	C	Silent	p.D306	1
ZC3H15	COAD	chr2	187370226	187370226	C	A	Missense_Mutation	p.L256I	1
ZC3H15	STAD	chr2	187359984	187359984	A	C	Missense_Mutation	p.K34Q	1
ZC3H15	GBM	chr2	187368763	187368763	G	A	Missense_Mutation		1
ZC3H15	MESO	chr2	187370669	187370669	C	A	Missense_Mutation		1
ZC3H15	COAD	chr2	187373434	187373434	T	G	Missense_Mutation	p.L419V	1
ZC3H15	STAD	chr2	187370510	187370512	ATG	-	In_Frame_Del	p.N303del	1
ZC3H15	HNSC	chr2	187364950	187364950	C	G	Missense_Mutation		1
ZC3H15	LIHC	chr2	187370241	187370241	A	G	Missense_Mutation		1
ZC3H15	STAD	chr2	187368933	187368934	-	GA	Frame_Shift_Ins	p.I236fs	1
ZC3H15	HNSC	chr2	187370222	187370222	T	A	Silent		1
ZC3H15	LIHC	chr2	187373311	187373311	G	T	Missense_Mutation		1
ZC3H15	SKCM	chr2	187370230	187370230	C	A	Missense_Mutation	p.A257D	1
ZC3H15	ESCA	chr2	187364362	187364362	G	T	Missense_Mutation	p.C65F	1
ZC3H15	LIHC	chr2	187351159	187351159	A	-	Frame_Shift_Del	p.Q17fs	1
ZC3H15	STAD	chr2	187366110	187366110	C	T	Nonsense_Mutation		1

Copy number variation (CNV) of ZC3H15
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across ZC3H15
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
68628	STAD	TCGA-HU-A4GH-01A	BRD4	chr19	15442647	-	ZC3H15	chr2	187367223	+
68628	STAD	TCGA-HU-A4GH-01A	BRD4	chr19	15443101	-	ZC3H15	chr2	187367223	+
68628	STAD	TCGA-HU-A4GT-01A	CERS6	chr2	169487552	+	ZC3H15	chr2	187359960	+
68628	N/A	BQ946452	GOLGA3	chr12	133402787	-	ZC3H15	chr2	187367285	+
68628	N/A	BM151158	KDM5A	chr12	427145	-	ZC3H15	chr2	187374085	-
68628	N/A	FN172222	PRKACB	chr1	84686013	+	ZC3H15	chr2	187365022	-
100540	N/A	BI496896	ZC3H15	chr2	187374088	+	ABCB4	chr7	87063442	-
100540	PRAD	TCGA-KC-A7F3-01A	ZC3H15	chr2	187351184	+	CPS1	chr2	211454830	+
100540	BRCA	TCGA-AC-A6IW-01A	ZC3H15	chr2	187351183	+	FAM171B	chr2	187604954	+
100540	BRCA	TCGA-AC-A6IW-01A	ZC3H15	chr2	187351184	+	FAM171B	chr2	187604955	+
100540	LUSC	TCGA-21-5783-01A	ZC3H15	chr2	187366152	+	FAM171B	chr2	187604955	+
100540	SKCM	TCGA-EB-A57M-01A	ZC3H15	chr2	187351184	+	GULP1	chr2	189342386	+
100540	STAD	TCGA-BR-8676-01A	ZC3H15	chr2	187351184	+	ITGAV	chr2	187487066	+
100540	STAD	TCGA-CD-8530-01A	ZC3H15	chr2	187360061	+	NCKAP1	chr2	183888644	-
100540	PRAD	TCGA-G9-6348-01A	ZC3H15	chr2	187351184	+	SERINC1	chr6	122779826	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUAD	ZC3H15	0.00191427728588656	0.05
SARC	ZC3H15	0.00463291688339593	0.12
LUSC	ZC3H15	0.00798448425612812	0.19
HNSC	ZC3H15	0.013882499511211	0.32
KIRP	ZC3H15	2.24079736878965e-05	0.00063
TGCT	ZC3H15	4.89135747722409e-05	0.0013

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	ZC3H15	0.0297648506810154	0.92
LUSC	ZC3H15	0.0165684117225991	0.53
THCA	ZC3H15	0.00871287507735621	0.29
PRAD	ZC3H15	0.0459762638647746	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source