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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: ROCK1 (NCBI Gene ID:6093)

Gene Summary

Gene Summary

Gene Information	Gene Name: ROCK1
	Gene ID: 6093
	Gene Symbol	ROCK1
	Gene ID	6093
	Gene Name	Rho associated coiled-coil containing protein kinase 1
	Synonyms	P160ROCK\|ROCK-I
	Cytomap	18q11.1
	Type of Gene	protein-coding
	Description	rho-associated protein kinase 1p160 ROCK-1renal carcinoma antigen NY-REN-35
	Modification date	20200322
	UniProtAcc	Q13464

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0017148	Negative regulation of translation
GO:0006417	Regulation of translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ROCK1	GO:0006468	protein phosphorylation	23093407
Hgene	ROCK1	GO:0007159	leukocyte cell-cell adhesion	12082081
Hgene	ROCK1	GO:0018105	peptidyl-serine phosphorylation	18573880
Hgene	ROCK1	GO:0022614	membrane to membrane docking	12082081
Hgene	ROCK1	GO:0030334	regulation of cell migration	23093407
Hgene	ROCK1	GO:0032091	negative regulation of protein binding	18573880
Hgene	ROCK1	GO:0032956	regulation of actin cytoskeleton organization	25911094
Hgene	ROCK1	GO:0050900	leukocyte migration	12082081
Hgene	ROCK1	GO:0050901	leukocyte tethering or rolling	12082081
Hgene	ROCK1	GO:0070507	regulation of microtubule cytoskeleton organization	23093407

Inferred gene age of translation factor.

Gene

Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25

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Translation Studies in PubMed

We searched PubMed using 'ROCK1[title] AND translation [title] AND human.'

Gene	Title	PMID
ROCK1	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000399799	18534743	18535005	Frame-shift
ENST00000399799	18546877	18547037	Frame-shift
ENST00000399799	18559870	18559965	Frame-shift
ENST00000399799	18571136	18571287	Frame-shift
ENST00000399799	18586311	18586558	Frame-shift
ENST00000399799	18629052	18629190	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000399799	18629052	18629190	9501	1218	1355	1354	92	138

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q13464	92	138	2	1354	Chain	ID=PRO_0000086619;Note=Rho-associated protein kinase 1
Q13464	92	138	76	338	Domain	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
Q13464	92	138	105	105	Binding site	Note=ATP;Ontology_term=ECO:0000255;evidence=ECO:0000255\|PROSITE-ProRule:PRU00159
Q13464	92	138	108	108	Natural variant	ID=VAR_041055;Note=S->N;Ontology_term=ECO:0000269;evidence=ECO:0000269\|PubMed:17344846;Dbxref=dbSNP:rs55811609,PMID:17344846
Q13464	92	138	86	95	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3V8S
Q13464	92	138	96	98	Turn	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3V8S
Q13464	92	138	101	108	Beta strand	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3V8S
Q13464	92	138	109	114	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3V8S
Q13464	92	138	121	130	Helix	Ontology_term=ECO:0000244;evidence=ECO:0000244\|PDB:3V8S

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUAD	ROCK1	-1.22542825445831	0.000657694699003642
BLCA	ROCK1	-2.67545203019099	0.00823211669921875
LUSC	ROCK1	-1.36763611486774	2.97304569684865e-06

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
READ	ROCK1	-0.068793136	0.011935335
SARC	ROCK1	0.124010969	0.046537777

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with ROCK1 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
BRCA	CGC	ROCK1	ASXL2	0.813505236	1.56E-288
BRCA	Epifactor	ROCK1	ASXL2	0.813505236	1.56E-288
CESC	Epifactor	ROCK1	REST	0.823559291	2.47E-77
CESC	IUPHAR	ROCK1	HIPK3	0.810831978	3.65E-73
CESC	Kinase	ROCK1	HIPK3	0.810831978	3.65E-73
CESC	TF	ROCK1	REST	0.823559291	2.47E-77
CHOL	Cell metabolism gene	ROCK1	PIK3CA	0.807237342	2.11E-11
CHOL	Cell metabolism gene	ROCK1	PAFAH1B2	0.848434336	1.86E-13
CHOL	CGC	ROCK1	NFATC2	0.801852494	3.60E-11
CHOL	CGC	ROCK1	STRN	0.806586606	2.25E-11
CHOL	CGC	ROCK1	PIK3CA	0.807237342	2.11E-11
CHOL	CGC	ROCK1	ASXL2	0.809004008	1.76E-11
CHOL	CGC	ROCK1	PAFAH1B2	0.848434336	1.86E-13
CHOL	Epifactor	ROCK1	ASXL2	0.809004008	1.76E-11
CHOL	Epifactor	ROCK1	REST	0.845419714	2.75E-13
CHOL	IUPHAR	ROCK1	ADAM10	0.800206645	4.23E-11
CHOL	IUPHAR	ROCK1	PIK3CA	0.807237342	2.11E-11
CHOL	IUPHAR	ROCK1	NIPAL2	0.811682138	1.34E-11
CHOL	IUPHAR	ROCK1	TAOK1	0.811685016	1.34E-11
CHOL	IUPHAR	ROCK1	DPP8	0.818395859	6.60E-12
CHOL	Kinase	ROCK1	TAOK1	0.811685016	1.34E-11
CHOL	TF	ROCK1	NFATC2	0.801852494	3.60E-11
CHOL	TF	ROCK1	ZNF791	0.825869834	2.90E-12
CHOL	TF	ROCK1	ZNF699	0.828390741	2.17E-12
CHOL	TF	ROCK1	REST	0.845419714	2.75E-13
CHOL	TSG	ROCK1	NFATC2	0.801852494	3.60E-11
DLBC	Cell metabolism gene	ROCK1	MED12	0.80202862	7.30E-12
DLBC	Cell metabolism gene	ROCK1	PDP2	0.806889822	4.36E-12
DLBC	Cell metabolism gene	ROCK1	PDPR	0.809225261	3.39E-12
DLBC	Cell metabolism gene	ROCK1	PAFAH1B2	0.812265873	2.42E-12
DLBC	Cell metabolism gene	ROCK1	MAN1A2	0.820342702	9.68E-13
DLBC	Cell metabolism gene	ROCK1	NCOA2	0.82099868	8.96E-13
DLBC	Cell metabolism gene	ROCK1	NCOR1	0.82114321	8.81E-13
DLBC	Cell metabolism gene	ROCK1	ENTPD5	0.823804923	6.43E-13
DLBC	Cell metabolism gene	ROCK1	POLR3A	0.825062134	5.54E-13
DLBC	Cell metabolism gene	ROCK1	XRN2	0.827511074	4.12E-13
DLBC	Cell metabolism gene	ROCK1	SMG1	0.828158182	3.80E-13
DLBC	Cell metabolism gene	ROCK1	CLOCK	0.828645243	3.58E-13
DLBC	Cell metabolism gene	ROCK1	PIK3C2A	0.828693477	3.56E-13
DLBC	Cell metabolism gene	ROCK1	ME2	0.832320708	2.27E-13
DLBC	Cell metabolism gene	ROCK1	IQGAP1	0.839327704	9.21E-14
DLBC	Cell metabolism gene	ROCK1	UGCG	0.840856369	7.52E-14
DLBC	Cell metabolism gene	ROCK1	IPMK	0.847310423	3.12E-14
DLBC	Cell metabolism gene	ROCK1	MED1	0.857131275	7.57E-15
DLBC	Cell metabolism gene	ROCK1	PRKAR2A	0.86569614	2.01E-15
DLBC	Cell metabolism gene	ROCK1	LMAN1	0.866232201	1.84E-15
DLBC	Cell metabolism gene	ROCK1	EP300	0.879408007	1.97E-16
DLBC	Cell metabolism gene	ROCK1	SIN3A	0.893444163	1.34E-17
DLBC	CGC	ROCK1	BCLAF1	0.801931701	7.38E-12
DLBC	CGC	ROCK1	MED12	0.80202862	7.30E-12
DLBC	CGC	ROCK1	DICER1	0.803076182	6.54E-12
DLBC	CGC	ROCK1	AFF4	0.807443746	4.11E-12
DLBC	CGC	ROCK1	ATRX	0.812002232	2.50E-12
DLBC	CGC	ROCK1	PAFAH1B2	0.812265873	2.42E-12
DLBC	CGC	ROCK1	PBRM1	0.817161482	1.40E-12
DLBC	CGC	ROCK1	NCOA2	0.82099868	8.96E-13
DLBC	CGC	ROCK1	NCOR1	0.82114321	8.81E-13
DLBC	CGC	ROCK1	PPM1D	0.826898878	4.44E-13
DLBC	CGC	ROCK1	TRIP11	0.827937442	3.91E-13
DLBC	CGC	ROCK1	ARHGAP5	0.828217855	3.78E-13
DLBC	CGC	ROCK1	BIRC6	0.829559344	3.20E-13
DLBC	CGC	ROCK1	CBL	0.831317891	2.57E-13
DLBC	CGC	ROCK1	BRD4	0.833157426	2.04E-13
DLBC	CGC	ROCK1	STAG2	0.835864409	1.45E-13
DLBC	CGC	ROCK1	STAG1	0.838277205	1.06E-13
DLBC	CGC	ROCK1	SPEN	0.840533209	7.85E-14
DLBC	CGC	ROCK1	NFATC2	0.843926645	4.98E-14
DLBC	CGC	ROCK1	TRRAP	0.844569355	4.56E-14
DLBC	CGC	ROCK1	IL6ST	0.845970911	3.76E-14
DLBC	CGC	ROCK1	BARD1	0.84882416	2.53E-14
DLBC	CGC	ROCK1	PTPN11	0.850660516	1.95E-14
DLBC	CGC	ROCK1	NSD1	0.85484448	1.06E-14
DLBC	CGC	ROCK1	AKAP9	0.864397354	2.47E-15
DLBC	CGC	ROCK1	ARID1A	0.866109474	1.88E-15
DLBC	CGC	ROCK1	LATS1	0.871517766	7.74E-16
DLBC	CGC	ROCK1	EP300	0.879408007	1.97E-16
DLBC	CGC	ROCK1	N4BP2	0.880529463	1.61E-16
DLBC	CGC	ROCK1	ASXL2	0.881677731	1.30E-16
DLBC	CGC	ROCK1	STRN	0.882663798	1.09E-16
DLBC	Epifactor	ROCK1	SIRT1	0.800072376	8.95E-12
DLBC	Epifactor	ROCK1	PPP4R2	0.802518682	6.94E-12
DLBC	Epifactor	ROCK1	CHD1	0.805099802	5.28E-12
DLBC	Epifactor	ROCK1	TAF2	0.806841704	4.38E-12
DLBC	Epifactor	ROCK1	PHF2	0.806917585	4.35E-12
DLBC	Epifactor	ROCK1	ATXN7	0.807593283	4.04E-12
DLBC	Epifactor	ROCK1	PHF8	0.808860544	3.52E-12
DLBC	Epifactor	ROCK1	ASH1L	0.810034963	3.10E-12
DLBC	Epifactor	ROCK1	ATRX	0.812002232	2.50E-12
DLBC	Epifactor	ROCK1	ATF7IP	0.81432693	1.93E-12
DLBC	Epifactor	ROCK1	PBRM1	0.817161482	1.40E-12
DLBC	Epifactor	ROCK1	MBD1	0.817315183	1.37E-12
DLBC	Epifactor	ROCK1	ATAD2B	0.817573343	1.33E-12
DLBC	Epifactor	ROCK1	BAZ1B	0.818713808	1.17E-12
DLBC	Epifactor	ROCK1	SETD5	0.819550504	1.06E-12
DLBC	Epifactor	ROCK1	NCOA2	0.82099868	8.96E-13
DLBC	Epifactor	ROCK1	NCOR1	0.82114321	8.81E-13
DLBC	Epifactor	ROCK1	RBBP5	0.821912961	8.05E-13
DLBC	Epifactor	ROCK1	CLOCK	0.828645243	3.58E-13
DLBC	Epifactor	ROCK1	SP1	0.83084049	2.73E-13
DLBC	Epifactor	ROCK1	MYSM1	0.831478079	2.52E-13
DLBC	Epifactor	ROCK1	CHD9	0.832546599	2.21E-13
DLBC	Epifactor	ROCK1	BRD4	0.833157426	2.04E-13
DLBC	Epifactor	ROCK1	IKZF3	0.835061569	1.60E-13
DLBC	Epifactor	ROCK1	ATF2	0.836212288	1.38E-13
DLBC	Epifactor	ROCK1	UBR2	0.837988463	1.10E-13
DLBC	Epifactor	ROCK1	SPEN	0.840533209	7.85E-14
DLBC	Epifactor	ROCK1	ADNP	0.841138879	7.25E-14
DLBC	Epifactor	ROCK1	ARID4A	0.84164929	6.77E-14
DLBC	Epifactor	ROCK1	SMARCAD1	0.843862229	5.02E-14
DLBC	Epifactor	ROCK1	TRRAP	0.844569355	4.56E-14
DLBC	Epifactor	ROCK1	CTR9	0.848678215	2.58E-14
DLBC	Epifactor	ROCK1	BARD1	0.84882416	2.53E-14
DLBC	Epifactor	ROCK1	KDM3B	0.849118503	2.42E-14
DLBC	Epifactor	ROCK1	CHD8	0.85157847	1.71E-14
DLBC	Epifactor	ROCK1	C11orf30	0.851783924	1.66E-14
DLBC	Epifactor	ROCK1	NIPBL	0.851874321	1.64E-14
DLBC	Epifactor	ROCK1	NSD1	0.85484448	1.06E-14
DLBC	Epifactor	ROCK1	EPC1	0.859723911	5.11E-15
DLBC	Epifactor	ROCK1	RNF168	0.862020168	3.59E-15
DLBC	Epifactor	ROCK1	ARID1A	0.866109474	1.88E-15
DLBC	Epifactor	ROCK1	SHPRH	0.878882124	2.16E-16
DLBC	Epifactor	ROCK1	EP300	0.879408007	1.97E-16
DLBC	Epifactor	ROCK1	ASXL2	0.881677731	1.30E-16
DLBC	Epifactor	ROCK1	REST	0.891178029	2.11E-17
DLBC	Epifactor	ROCK1	SIN3A	0.893444163	1.34E-17
DLBC	IUPHAR	ROCK1	SIRT1	0.800072376	8.95E-12
DLBC	IUPHAR	ROCK1	PHF2	0.806917585	4.35E-12
DLBC	IUPHAR	ROCK1	PHF8	0.808860544	3.52E-12
DLBC	IUPHAR	ROCK1	ASH1L	0.810034963	3.10E-12
DLBC	IUPHAR	ROCK1	OSMR	0.811855138	2.54E-12
DLBC	IUPHAR	ROCK1	ATP2A2	0.81230087	2.41E-12
DLBC	IUPHAR	ROCK1	PBRM1	0.817161482	1.40E-12
DLBC	IUPHAR	ROCK1	TRPM7	0.817428036	1.35E-12
DLBC	IUPHAR	ROCK1	ATAD2B	0.817573343	1.33E-12
DLBC	IUPHAR	ROCK1	TAOK1	0.817761201	1.30E-12
DLBC	IUPHAR	ROCK1	BAZ1B	0.818713808	1.17E-12
DLBC	IUPHAR	ROCK1	WNK1	0.819779359	1.03E-12
DLBC	IUPHAR	ROCK1	LMTK2	0.820574277	9.42E-13
DLBC	IUPHAR	ROCK1	NCOA2	0.82099868	8.96E-13
DLBC	IUPHAR	ROCK1	PPM1D	0.826898878	4.44E-13
DLBC	IUPHAR	ROCK1	SMG1	0.828158182	3.80E-13
DLBC	IUPHAR	ROCK1	CLOCK	0.828645243	3.58E-13
DLBC	IUPHAR	ROCK1	PIK3C2A	0.828693477	3.56E-13
DLBC	IUPHAR	ROCK1	TNKS2	0.828818331	3.51E-13
DLBC	IUPHAR	ROCK1	BIRC6	0.829559344	3.20E-13
DLBC	IUPHAR	ROCK1	PDPK1	0.832790795	2.14E-13
DLBC	IUPHAR	ROCK1	BRD4	0.833157426	2.04E-13
DLBC	IUPHAR	ROCK1	ADAM10	0.837264247	1.21E-13
DLBC	IUPHAR	ROCK1	ERN1	0.837778194	1.13E-13
DLBC	IUPHAR	ROCK1	SLC30A6	0.837992575	1.10E-13
DLBC	IUPHAR	ROCK1	UGCG	0.840856369	7.52E-14
DLBC	IUPHAR	ROCK1	TRRAP	0.844569355	4.56E-14
DLBC	IUPHAR	ROCK1	TTBK2	0.844640877	4.52E-14
DLBC	IUPHAR	ROCK1	IL6ST	0.845970911	3.76E-14
DLBC	IUPHAR	ROCK1	SCYL2	0.846132875	3.68E-14
DLBC	IUPHAR	ROCK1	EPB41	0.848851482	2.52E-14
DLBC	IUPHAR	ROCK1	KDM3B	0.849118503	2.42E-14
DLBC	IUPHAR	ROCK1	DPP8	0.849465552	2.31E-14
DLBC	IUPHAR	ROCK1	CLCN3	0.851565757	1.71E-14
DLBC	IUPHAR	ROCK1	NSD1	0.85484448	1.06E-14
DLBC	IUPHAR	ROCK1	NR2C2	0.855041814	1.03E-14
DLBC	IUPHAR	ROCK1	HIPK3	0.858917325	5.78E-15
DLBC	IUPHAR	ROCK1	PRKAR2A	0.86569614	2.01E-15
DLBC	IUPHAR	ROCK1	LATS1	0.871517766	7.74E-16
DLBC	IUPHAR	ROCK1	EP300	0.879408007	1.97E-16
DLBC	Kinase	ROCK1	TRPM7	0.817428036	1.35E-12
DLBC	Kinase	ROCK1	TAOK1	0.817761201	1.30E-12
DLBC	Kinase	ROCK1	BAZ1B	0.818713808	1.17E-12
DLBC	Kinase	ROCK1	WNK1	0.819779359	1.03E-12
DLBC	Kinase	ROCK1	LMTK2	0.820574277	9.42E-13
DLBC	Kinase	ROCK1	SMG1	0.828158182	3.80E-13
DLBC	Kinase	ROCK1	PDPK1	0.832790795	2.14E-13
DLBC	Kinase	ROCK1	BRD4	0.833157426	2.04E-13
DLBC	Kinase	ROCK1	ERN1	0.837778194	1.13E-13
DLBC	Kinase	ROCK1	TRRAP	0.844569355	4.56E-14
DLBC	Kinase	ROCK1	TTBK2	0.844640877	4.52E-14
DLBC	Kinase	ROCK1	SCYL2	0.846132875	3.68E-14
DLBC	Kinase	ROCK1	HIPK3	0.858917325	5.78E-15
DLBC	Kinase	ROCK1	LATS1	0.871517766	7.74E-16
DLBC	TF	ROCK1	RLF	0.800048438	8.97E-12
DLBC	TF	ROCK1	SP3	0.801649846	7.60E-12
DLBC	TF	ROCK1	ZNF426	0.802736243	6.78E-12
DLBC	TF	ROCK1	ZNF699	0.806667254	4.47E-12
DLBC	TF	ROCK1	ASH1L	0.810034963	3.10E-12
DLBC	TF	ROCK1	ATF7	0.810503549	2.94E-12
DLBC	TF	ROCK1	ZNF567	0.811101543	2.76E-12
DLBC	TF	ROCK1	FOXN2	0.815018105	1.78E-12
DLBC	TF	ROCK1	BBX	0.816516355	1.50E-12
DLBC	TF	ROCK1	ZNF641	0.816553958	1.50E-12
DLBC	TF	ROCK1	MBD1	0.817315183	1.37E-12
DLBC	TF	ROCK1	NCOA2	0.82099868	8.96E-13
DLBC	TF	ROCK1	NFXL1	0.821582953	8.37E-13
DLBC	TF	ROCK1	SP2	0.823627321	6.57E-13
DLBC	TF	ROCK1	ZNF800	0.82518388	5.46E-13
DLBC	TF	ROCK1	ETV3	0.827859794	3.95E-13
DLBC	TF	ROCK1	CLOCK	0.828645243	3.58E-13
DLBC	TF	ROCK1	SP4	0.828698774	3.56E-13
DLBC	TF	ROCK1	SP1	0.83084049	2.73E-13
DLBC	TF	ROCK1	ZNF41	0.831010342	2.67E-13
DLBC	TF	ROCK1	MYSM1	0.831478079	2.52E-13
DLBC	TF	ROCK1	SON	0.832690628	2.17E-13
DLBC	TF	ROCK1	ZNF430	0.833291193	2.01E-13
DLBC	TF	ROCK1	IKZF3	0.835061569	1.60E-13
DLBC	TF	ROCK1	TSHZ1	0.835209413	1.57E-13
DLBC	TF	ROCK1	ZFX	0.835637061	1.49E-13
DLBC	TF	ROCK1	ATF2	0.836212288	1.38E-13
DLBC	TF	ROCK1	ZNF407	0.837349533	1.19E-13
DLBC	TF	ROCK1	ZNF281	0.838332838	1.05E-13
DLBC	TF	ROCK1	ZNF827	0.840500802	7.89E-14
DLBC	TF	ROCK1	SPEN	0.840533209	7.85E-14
DLBC	TF	ROCK1	ADNP	0.841138879	7.25E-14
DLBC	TF	ROCK1	ZNF609	0.841334102	7.06E-14
DLBC	TF	ROCK1	NFATC2	0.843926645	4.98E-14
DLBC	TF	ROCK1	ZNF644	0.845776545	3.86E-14
DLBC	TF	ROCK1	ZNF776	0.846187991	3.65E-14
DLBC	TF	ROCK1	NR2C2	0.855041814	1.03E-14
DLBC	TF	ROCK1	ZBTB11	0.855367527	9.84E-15
DLBC	TF	ROCK1	RREB1	0.857582128	7.07E-15
DLBC	TF	ROCK1	ZNF432	0.858808919	5.88E-15
DLBC	TF	ROCK1	HIVEP1	0.861814243	3.71E-15
DLBC	TF	ROCK1	ZNF236	0.863403067	2.89E-15
DLBC	TF	ROCK1	TMF1	0.86372509	2.75E-15
DLBC	TF	ROCK1	ZKSCAN1	0.87234338	6.74E-16
DLBC	TF	ROCK1	ZNF611	0.873801089	5.26E-16
DLBC	TF	ROCK1	REST	0.891178029	2.11E-17
DLBC	TSG	ROCK1	SIRT1	0.800072376	8.95E-12
DLBC	TSG	ROCK1	RB1CC1	0.80044004	8.62E-12
DLBC	TSG	ROCK1	DICER1	0.803076182	6.54E-12
DLBC	TSG	ROCK1	CHD1	0.805099802	5.28E-12
DLBC	TSG	ROCK1	RASSF3	0.810885683	2.82E-12
DLBC	TSG	ROCK1	PBRM1	0.817161482	1.40E-12
DLBC	TSG	ROCK1	RNF111	0.825896639	5.01E-13
DLBC	TSG	ROCK1	CBL	0.831317891	2.57E-13
DLBC	TSG	ROCK1	IKZF3	0.835061569	1.60E-13
DLBC	TSG	ROCK1	SMCHD1	0.836383805	1.35E-13
DLBC	TSG	ROCK1	NFATC2	0.843926645	4.98E-14
DLBC	TSG	ROCK1	BARD1	0.84882416	2.53E-14
DLBC	TSG	ROCK1	EPB41	0.848851482	2.52E-14
DLBC	TSG	ROCK1	KDM3B	0.849118503	2.42E-14
DLBC	TSG	ROCK1	PTPN11	0.850660516	1.95E-14
DLBC	TSG	ROCK1	NR2C2	0.855041814	1.03E-14
DLBC	TSG	ROCK1	HIVEP1	0.861814243	3.71E-15
DLBC	TSG	ROCK1	ARID1A	0.866109474	1.88E-15
DLBC	TSG	ROCK1	RBL1	0.866619176	1.73E-15
DLBC	TSG	ROCK1	LATS1	0.871517766	7.74E-16
DLBC	TSG	ROCK1	SHPRH	0.878882124	2.16E-16
HNSC	CGC	ROCK1	ASXL2	0.803924243	2.18E-129
HNSC	Epifactor	ROCK1	REST	0.802373032	1.58E-128
HNSC	Epifactor	ROCK1	ASXL2	0.803924243	2.18E-129
HNSC	TF	ROCK1	REST	0.802373032	1.58E-128
KIRP	Cell metabolism gene	ROCK1	PIK3C2A	0.801734885	9.77E-74
KIRP	Cell metabolism gene	ROCK1	CLOCK	0.80591869	4.60E-75
KIRP	Cell metabolism gene	ROCK1	PIK3CA	0.830107411	1.99E-83
KIRP	CGC	ROCK1	TRIP11	0.816036553	2.06E-78
KIRP	CGC	ROCK1	PIK3CA	0.830107411	1.99E-83
KIRP	CGC	ROCK1	N4BP2	0.846839613	4.99E-90
KIRP	CGC	ROCK1	ATRX	0.857083711	1.79E-94
KIRP	Epifactor	ROCK1	CHD9	0.802619006	5.15E-74
KIRP	Epifactor	ROCK1	CLOCK	0.80591869	4.60E-75
KIRP	Epifactor	ROCK1	NIPBL	0.807176749	1.81E-75
KIRP	Epifactor	ROCK1	REST	0.813140351	1.97E-77
KIRP	Epifactor	ROCK1	SHPRH	0.824283787	2.69E-81
KIRP	Epifactor	ROCK1	ATRX	0.857083711	1.79E-94
KIRP	Epifactor	ROCK1	RSF1	0.860753146	3.76E-96
KIRP	IUPHAR	ROCK1	PIK3C2A	0.801734885	9.77E-74
KIRP	IUPHAR	ROCK1	CLOCK	0.80591869	4.60E-75
KIRP	IUPHAR	ROCK1	SLK	0.811770179	5.64E-77
KIRP	IUPHAR	ROCK1	PIK3CA	0.830107411	1.99E-83
KIRP	Kinase	ROCK1	SLK	0.811770179	5.64E-77
KIRP	TF	ROCK1	BBX	0.805560304	5.99E-75
KIRP	TF	ROCK1	CLOCK	0.80591869	4.60E-75
KIRP	TF	ROCK1	ZNF430	0.808670235	5.92E-76
KIRP	TF	ROCK1	TMF1	0.811848405	5.31E-77
KIRP	TF	ROCK1	REST	0.813140351	1.97E-77
KIRP	TF	ROCK1	ZNF791	0.835201427	2.33E-85
KIRP	TSG	ROCK1	SMCHD1	0.800627886	2.17E-73
KIRP	TSG	ROCK1	SHPRH	0.824283787	2.69E-81
LIHC	Cell metabolism gene	ROCK1	PIK3CA	0.80776073	1.14E-98
LIHC	CGC	ROCK1	BIRC6	0.803232705	9.12E-97
LIHC	CGC	ROCK1	PIK3CA	0.80776073	1.14E-98
LIHC	CGC	ROCK1	STRN	0.838082529	7.43E-113
LIHC	Epifactor	ROCK1	REST	0.822428581	3.42E-105
LIHC	IUPHAR	ROCK1	BIRC6	0.803232705	9.12E-97
LIHC	IUPHAR	ROCK1	PIK3CA	0.80776073	1.14E-98
LIHC	IUPHAR	ROCK1	DPP8	0.818459053	2.28E-103
LIHC	IUPHAR	ROCK1	HIPK3	0.823796974	7.85E-106
LIHC	Kinase	ROCK1	HIPK3	0.823796974	7.85E-106
LIHC	TF	ROCK1	REST	0.822428581	3.42E-105
PAAD	Cell metabolism gene	ROCK1	NCOA2	0.818167663	2.27E-45
PAAD	CGC	ROCK1	LATS1	0.814644462	1.09E-44
PAAD	CGC	ROCK1	NCOA2	0.818167663	2.27E-45
PAAD	CGC	ROCK1	IL6ST	0.831056795	5.46E-48
PAAD	CGC	ROCK1	ASXL2	0.847720314	1.01E-51
PAAD	Epifactor	ROCK1	PPP4R2	0.800471011	4.27E-42
PAAD	Epifactor	ROCK1	REST	0.815400457	7.78E-45
PAAD	Epifactor	ROCK1	NCOA2	0.818167663	2.27E-45
PAAD	Epifactor	ROCK1	ASXL2	0.847720314	1.01E-51
PAAD	IUPHAR	ROCK1	LATS1	0.814644462	1.09E-44
PAAD	IUPHAR	ROCK1	NCOA2	0.818167663	2.27E-45
PAAD	IUPHAR	ROCK1	TAOK1	0.819821456	1.07E-45
PAAD	IUPHAR	ROCK1	MAP3K2	0.826211114	5.58E-47
PAAD	IUPHAR	ROCK1	IL6ST	0.831056795	5.46E-48
PAAD	IUPHAR	ROCK1	HIPK3	0.841977972	2.18E-50
PAAD	Kinase	ROCK1	LATS1	0.814644462	1.09E-44
PAAD	Kinase	ROCK1	TAOK1	0.819821456	1.07E-45
PAAD	Kinase	ROCK1	MAP3K2	0.826211114	5.58E-47
PAAD	Kinase	ROCK1	HIPK3	0.841977972	2.18E-50
PAAD	TF	ROCK1	REST	0.815400457	7.78E-45
PAAD	TF	ROCK1	NCOA2	0.818167663	2.27E-45
PAAD	TSG	ROCK1	LATS1	0.814644462	1.09E-44
PCPG	Cell metabolism gene	ROCK1	NCOA2	0.814576783	1.25E-45
PCPG	CGC	ROCK1	NCOA2	0.814576783	1.25E-45
PCPG	CGC	ROCK1	ASXL2	0.824324763	1.37E-47
PCPG	Epifactor	ROCK1	TAF1L	0.802781477	2.09E-43
PCPG	Epifactor	ROCK1	NCOA2	0.814576783	1.25E-45
PCPG	Epifactor	ROCK1	ASXL2	0.824324763	1.37E-47
PCPG	Epifactor	ROCK1	ATF2	0.836877008	2.69E-50
PCPG	IUPHAR	ROCK1	TAF1L	0.802781477	2.09E-43
PCPG	IUPHAR	ROCK1	DPP8	0.802992445	1.91E-43
PCPG	IUPHAR	ROCK1	ADAM10	0.805803036	5.82E-44
PCPG	IUPHAR	ROCK1	HIPK3	0.813262392	2.25E-45
PCPG	IUPHAR	ROCK1	NCOA2	0.814576783	1.25E-45
PCPG	Kinase	ROCK1	TAF1L	0.802781477	2.09E-43
PCPG	Kinase	ROCK1	HIPK3	0.813262392	2.25E-45
PCPG	TF	ROCK1	ZKSCAN1	0.804738404	9.15E-44
PCPG	TF	ROCK1	ZNF791	0.808047091	2.22E-44
PCPG	TF	ROCK1	ZNF397	0.813349352	2.17E-45
PCPG	TF	ROCK1	NCOA2	0.814576783	1.25E-45
PCPG	TF	ROCK1	ZNF281	0.81892262	1.73E-46
PCPG	TF	ROCK1	ATF2	0.836877008	2.69E-50
PCPG	TF	ROCK1	ZNF699	0.841155626	2.84E-51
PRAD	Cell metabolism gene	ROCK1	IQGAP1	0.803089501	2.54E-125
PRAD	Cell metabolism gene	ROCK1	MAN1A2	0.808888323	1.69E-128
PRAD	Cell metabolism gene	ROCK1	MAN2A1	0.810713477	1.60E-129
PRAD	Cell metabolism gene	ROCK1	PRKAR2A	0.81338755	4.85E-131
PRAD	Cell metabolism gene	ROCK1	UGCG	0.823533232	4.92E-137
PRAD	Cell metabolism gene	ROCK1	EP300	0.824281809	1.72E-137
PRAD	Cell metabolism gene	ROCK1	NUP153	0.831715705	3.72E-142
PRAD	Cell metabolism gene	ROCK1	NCOA2	0.837242471	8.98E-146
PRAD	Cell metabolism gene	ROCK1	MED13L	0.837913694	3.19E-146
PRAD	Cell metabolism gene	ROCK1	IPMK	0.844689576	7.20E-151
PRAD	Cell metabolism gene	ROCK1	CLOCK	0.857376013	3.36E-160
PRAD	Cell metabolism gene	ROCK1	PIK3CA	0.85923066	1.22E-161
PRAD	Cell metabolism gene	ROCK1	PAFAH1B2	0.860767285	7.55E-163
PRAD	Cell metabolism gene	ROCK1	MGAT5	0.861160132	3.69E-163
PRAD	Cell metabolism gene	ROCK1	PIK3C2A	0.864361265	9.86E-166
PRAD	CGC	ROCK1	SMC1A	0.804353116	5.27E-126
PRAD	CGC	ROCK1	PTPN11	0.807529473	9.59E-128
PRAD	CGC	ROCK1	NF1	0.809388771	8.88E-129
PRAD	CGC	ROCK1	SETD2	0.811691109	4.49E-130
PRAD	CGC	ROCK1	TCF12	0.812662519	1.26E-130
PRAD	CGC	ROCK1	ARHGAP5	0.821616181	7.14E-136
PRAD	CGC	ROCK1	BIRC6	0.821803244	5.51E-136
PRAD	CGC	ROCK1	EP300	0.824281809	1.72E-137
PRAD	CGC	ROCK1	PBRM1	0.827050546	3.34E-139
PRAD	CGC	ROCK1	LATS1	0.830530123	2.14E-141
PRAD	CGC	ROCK1	NCOA2	0.837242471	8.98E-146
PRAD	CGC	ROCK1	N4BP2	0.841690111	8.74E-149
PRAD	CGC	ROCK1	STAG1	0.842292399	3.36E-149
PRAD	CGC	ROCK1	BARD1	0.850723927	3.37E-155
PRAD	CGC	ROCK1	ATRX	0.854090576	1.06E-157
PRAD	CGC	ROCK1	STRN	0.858931663	2.09E-161
PRAD	CGC	ROCK1	PIK3CA	0.85923066	1.22E-161
PRAD	CGC	ROCK1	PAFAH1B2	0.860767285	7.55E-163
PRAD	CGC	ROCK1	IL6ST	0.862829571	1.71E-164
PRAD	CGC	ROCK1	ASXL2	0.876238192	6.90E-176
PRAD	Epifactor	ROCK1	PPP4R2	0.801842456	1.19E-124
PRAD	Epifactor	ROCK1	NIPBL	0.801924354	1.07E-124
PRAD	Epifactor	ROCK1	KDM3B	0.80421002	6.31E-126
PRAD	Epifactor	ROCK1	BRWD3	0.806693244	2.77E-127
PRAD	Epifactor	ROCK1	SETD2	0.811691109	4.49E-130
PRAD	Epifactor	ROCK1	RNF168	0.813265838	5.69E-131
PRAD	Epifactor	ROCK1	RAD54L2	0.815521484	2.86E-132
PRAD	Epifactor	ROCK1	EPC1	0.820688112	2.58E-135
PRAD	Epifactor	ROCK1	EP300	0.824281809	1.72E-137
PRAD	Epifactor	ROCK1	C11orf30	0.826819511	4.65E-139
PRAD	Epifactor	ROCK1	PBRM1	0.827050546	3.34E-139
PRAD	Epifactor	ROCK1	TAF1L	0.830889414	1.26E-141
PRAD	Epifactor	ROCK1	RBBP5	0.831908476	2.80E-142
PRAD	Epifactor	ROCK1	TAF1	0.831932339	2.70E-142
PRAD	Epifactor	ROCK1	BPTF	0.833826676	1.60E-143
PRAD	Epifactor	ROCK1	NCOA2	0.837242471	8.98E-146
PRAD	Epifactor	ROCK1	ARID4A	0.840981822	2.67E-148
PRAD	Epifactor	ROCK1	BARD1	0.850723927	3.37E-155
PRAD	Epifactor	ROCK1	ATRX	0.854090576	1.06E-157
PRAD	Epifactor	ROCK1	ATF2	0.855738131	6.04E-159
PRAD	Epifactor	ROCK1	CLOCK	0.857376013	3.36E-160
PRAD	Epifactor	ROCK1	RSF1	0.866735771	1.10E-167
PRAD	Epifactor	ROCK1	REST	0.870645411	5.57E-171
PRAD	Epifactor	ROCK1	ASH1L	0.870895267	3.40E-171
PRAD	Epifactor	ROCK1	ASXL2	0.876238192	6.90E-176
PRAD	Epifactor	ROCK1	USP12	0.876851759	1.93E-176
PRAD	IUPHAR	ROCK1	LMTK2	0.802515219	5.18E-125
PRAD	IUPHAR	ROCK1	KDM3B	0.80421002	6.31E-126
PRAD	IUPHAR	ROCK1	ERN1	0.804295525	5.67E-126
PRAD	IUPHAR	ROCK1	LNPEP	0.804366851	5.18E-126
PRAD	IUPHAR	ROCK1	BRWD3	0.806693244	2.77E-127
PRAD	IUPHAR	ROCK1	ADAM17	0.809753543	5.55E-129
PRAD	IUPHAR	ROCK1	SOS1	0.811318488	7.30E-130
PRAD	IUPHAR	ROCK1	SETD2	0.811691109	4.49E-130
PRAD	IUPHAR	ROCK1	PRKAR2A	0.81338755	4.85E-131
PRAD	IUPHAR	ROCK1	SLC30A6	0.816398789	8.83E-133
PRAD	IUPHAR	ROCK1	BMPR2	0.817760725	1.41E-133
PRAD	IUPHAR	ROCK1	NR2C2	0.820872066	2.00E-135
PRAD	IUPHAR	ROCK1	BIRC6	0.821803244	5.51E-136
PRAD	IUPHAR	ROCK1	PXK	0.823133947	8.62E-137
PRAD	IUPHAR	ROCK1	UGCG	0.823533232	4.92E-137
PRAD	IUPHAR	ROCK1	EP300	0.824281809	1.72E-137
PRAD	IUPHAR	ROCK1	PBRM1	0.827050546	3.34E-139
PRAD	IUPHAR	ROCK1	PTPRG	0.827289002	2.37E-139
PRAD	IUPHAR	ROCK1	LATS1	0.830530123	2.14E-141
PRAD	IUPHAR	ROCK1	TAF1L	0.830889414	1.26E-141
PRAD	IUPHAR	ROCK1	TAF1	0.831932339	2.70E-142
PRAD	IUPHAR	ROCK1	TTBK2	0.833648827	2.09E-143
PRAD	IUPHAR	ROCK1	BPTF	0.833826676	1.60E-143
PRAD	IUPHAR	ROCK1	MAP3K2	0.834610192	4.93E-144
PRAD	IUPHAR	ROCK1	HIPK1	0.837149761	1.03E-145
PRAD	IUPHAR	ROCK1	NCOA2	0.837242471	8.98E-146
PRAD	IUPHAR	ROCK1	TAOK1	0.853124582	5.64E-157
PRAD	IUPHAR	ROCK1	CLOCK	0.857376013	3.36E-160
PRAD	IUPHAR	ROCK1	PIK3CA	0.85923066	1.22E-161
PRAD	IUPHAR	ROCK1	IL6ST	0.862829571	1.71E-164
PRAD	IUPHAR	ROCK1	PIK3C2A	0.864361265	9.86E-166
PRAD	IUPHAR	ROCK1	ASH1L	0.870895267	3.40E-171
PRAD	IUPHAR	ROCK1	HIPK3	0.873953315	7.45E-174
PRAD	IUPHAR	ROCK1	DPP8	0.884008394	4.09E-183
PRAD	Kinase	ROCK1	LMTK2	0.802515219	5.18E-125
PRAD	Kinase	ROCK1	ERN1	0.804295525	5.67E-126
PRAD	Kinase	ROCK1	BMPR2	0.817760725	1.41E-133
PRAD	Kinase	ROCK1	PXK	0.823133947	8.62E-137
PRAD	Kinase	ROCK1	LATS1	0.830530123	2.14E-141
PRAD	Kinase	ROCK1	TAF1L	0.830889414	1.26E-141
PRAD	Kinase	ROCK1	TAF1	0.831932339	2.70E-142
PRAD	Kinase	ROCK1	TTBK2	0.833648827	2.09E-143
PRAD	Kinase	ROCK1	MAP3K2	0.834610192	4.93E-144
PRAD	Kinase	ROCK1	HIPK1	0.837149761	1.03E-145
PRAD	Kinase	ROCK1	TAOK1	0.853124582	5.64E-157
PRAD	Kinase	ROCK1	HIPK3	0.873953315	7.45E-174
PRAD	TF	ROCK1	ZSCAN23	0.800738133	4.61E-124
PRAD	TF	ROCK1	ZNF619	0.807593259	8.84E-128
PRAD	TF	ROCK1	ZNF585B	0.808738368	2.05E-128
PRAD	TF	ROCK1	ZNF41	0.809943622	4.34E-129
PRAD	TF	ROCK1	TCF12	0.812662519	1.26E-130
PRAD	TF	ROCK1	ELK3	0.819051895	2.43E-134
PRAD	TF	ROCK1	NR2C2	0.820872066	2.00E-135
PRAD	TF	ROCK1	ZNF347	0.822904189	1.19E-136
PRAD	TF	ROCK1	ZNF704	0.82333845	6.47E-137
PRAD	TF	ROCK1	ZNF354C	0.827024534	3.47E-139
PRAD	TF	ROCK1	ZNF426	0.831448385	5.53E-142
PRAD	TF	ROCK1	BPTF	0.833826676	1.60E-143
PRAD	TF	ROCK1	ZNF281	0.836345885	3.54E-145
PRAD	TF	ROCK1	ZFP91	0.836396736	3.28E-145
PRAD	TF	ROCK1	ZNF699	0.837021442	1.26E-145
PRAD	TF	ROCK1	NCOA2	0.837242471	8.98E-146
PRAD	TF	ROCK1	ETV3	0.84093151	2.89E-148
PRAD	TF	ROCK1	ZNF641	0.848019966	3.10E-153
PRAD	TF	ROCK1	ZNF791	0.85087485	2.61E-155
PRAD	TF	ROCK1	ATF2	0.855738131	6.04E-159
PRAD	TF	ROCK1	CLOCK	0.857376013	3.36E-160
PRAD	TF	ROCK1	REST	0.870645411	5.57E-171
PRAD	TF	ROCK1	ASH1L	0.870895267	3.40E-171
PRAD	TSG	ROCK1	KDM3B	0.80421002	6.31E-126
PRAD	TSG	ROCK1	RBL1	0.80424468	6.04E-126
PRAD	TSG	ROCK1	PTPN11	0.807529473	9.59E-128
PRAD	TSG	ROCK1	NF1	0.809388771	8.88E-129
PRAD	TSG	ROCK1	SETD2	0.811691109	4.49E-130
PRAD	TSG	ROCK1	BMPR2	0.817760725	1.41E-133
PRAD	TSG	ROCK1	NR2C2	0.820872066	2.00E-135
PRAD	TSG	ROCK1	PBRM1	0.827050546	3.34E-139
PRAD	TSG	ROCK1	LATS1	0.830530123	2.14E-141
PRAD	TSG	ROCK1	RNF111	0.839508637	2.69E-147
PRAD	TSG	ROCK1	BARD1	0.850723927	3.37E-155
PRAD	TSG	ROCK1	USP12	0.876851759	1.93E-176
READ	CGC	ROCK1	NOTCH2	0.803660205	5.88E-25
READ	IUPHAR	ROCK1	NOTCH2	0.803660205	5.88E-25
READ	TSG	ROCK1	NOTCH2	0.803660205	5.88E-25
SKCM	Cell metabolism gene	ROCK1	MTMR6	0.807827528	1.98E-110
SKCM	Cell metabolism gene	ROCK1	FBXL3	0.839213803	5.87E-127
SKCM	Cell metabolism gene	ROCK1	PIK3CA	0.847188442	9.86E-132
SKCM	CGC	ROCK1	STAG1	0.800353351	6.13E-107
SKCM	CGC	ROCK1	SMAD4	0.808927057	5.90E-111
SKCM	CGC	ROCK1	KIF5B	0.809158133	4.57E-111
SKCM	CGC	ROCK1	BCLAF1	0.810184207	1.46E-111
SKCM	CGC	ROCK1	ATRX	0.818212107	1.53E-115
SKCM	CGC	ROCK1	SUZ12	0.823216998	4.00E-118
SKCM	CGC	ROCK1	PHF6	0.826038766	1.29E-119
SKCM	CGC	ROCK1	N4BP2	0.83551822	7.82E-125
SKCM	CGC	ROCK1	KTN1	0.84374417	1.23E-129
SKCM	CGC	ROCK1	PIK3CA	0.847188442	9.86E-132
SKCM	CGC	ROCK1	CREB1	0.848148389	2.52E-132
SKCM	Epifactor	ROCK1	SMARCAD1	0.800084208	8.13E-107
SKCM	Epifactor	ROCK1	PPP4R2	0.80034975	6.15E-107
SKCM	Epifactor	ROCK1	CHD9	0.806618781	7.44E-110
SKCM	Epifactor	ROCK1	REST	0.810123599	1.56E-111
SKCM	Epifactor	ROCK1	ATRX	0.818212107	1.53E-115
SKCM	Epifactor	ROCK1	SHPRH	0.819035028	5.83E-116
SKCM	Epifactor	ROCK1	EPC2	0.821048652	5.39E-117
SKCM	Epifactor	ROCK1	NIPBL	0.823171935	4.23E-118
SKCM	Epifactor	ROCK1	SUZ12	0.823216998	4.00E-118
SKCM	Epifactor	ROCK1	ATF2	0.827722605	1.61E-120
SKCM	Epifactor	ROCK1	ARID4B	0.83004426	8.82E-122
SKCM	Epifactor	ROCK1	SMEK2	0.831244279	1.93E-122
SKCM	Epifactor	ROCK1	ARID4A	0.831698239	1.08E-122
SKCM	Epifactor	ROCK1	JMJD1C	0.83786653	3.54E-126
SKCM	Epifactor	ROCK1	SMARCA5	0.841445373	2.88E-128
SKCM	IUPHAR	ROCK1	RIOK3	0.810833833	7.08E-112
SKCM	IUPHAR	ROCK1	SLK	0.817453563	3.71E-115
SKCM	IUPHAR	ROCK1	MAP3K2	0.817999244	1.96E-115
SKCM	IUPHAR	ROCK1	JMJD1C	0.83786653	3.54E-126
SKCM	IUPHAR	ROCK1	PIK3CA	0.847188442	9.86E-132
SKCM	Kinase	ROCK1	RIOK3	0.810833833	7.08E-112
SKCM	Kinase	ROCK1	SLK	0.817453563	3.71E-115
SKCM	Kinase	ROCK1	MAP3K2	0.817999244	1.96E-115
SKCM	TF	ROCK1	ZFX	0.804687302	6.05E-109
SKCM	TF	ROCK1	SMAD4	0.808927057	5.90E-111
SKCM	TF	ROCK1	REST	0.810123599	1.56E-111
SKCM	TF	ROCK1	TMF1	0.814782179	8.11E-114
SKCM	TF	ROCK1	SP3	0.818237444	1.49E-115
SKCM	TF	ROCK1	ATF2	0.827722605	1.61E-120
SKCM	TF	ROCK1	ZNF430	0.831705416	1.07E-122
SKCM	TF	ROCK1	ZNF148	0.833655797	8.79E-124
SKCM	TF	ROCK1	ZBTB11	0.840782875	7.08E-128
SKCM	TF	ROCK1	ZNF644	0.841068085	4.81E-128
SKCM	TF	ROCK1	ZNF791	0.843267766	2.37E-129
SKCM	TF	ROCK1	CREB1	0.848148389	2.52E-132
SKCM	TSG	ROCK1	SMAD4	0.808927057	5.90E-111
SKCM	TSG	ROCK1	SHPRH	0.819035028	5.83E-116
SKCM	TSG	ROCK1	SUZ12	0.823216998	4.00E-118
SKCM	TSG	ROCK1	PHF6	0.826038766	1.29E-119
SKCM	TSG	ROCK1	SMCHD1	0.864368748	5.13E-143
TGCT	Cell metabolism gene	ROCK1	MGAT5	0.803047687	1.90E-36
TGCT	Cell metabolism gene	ROCK1	NCOA2	0.838605986	1.80E-42
TGCT	CGC	ROCK1	NFATC2	0.805184151	8.98E-37
TGCT	CGC	ROCK1	ASXL2	0.825135864	4.98E-40
TGCT	CGC	ROCK1	REL	0.837763049	2.60E-42
TGCT	CGC	ROCK1	NCOA2	0.838605986	1.80E-42
TGCT	CGC	ROCK1	IL6ST	0.882691281	2.28E-52
TGCT	Epifactor	ROCK1	ASXL2	0.825135864	4.98E-40
TGCT	Epifactor	ROCK1	NCOA2	0.838605986	1.80E-42
TGCT	IUPHAR	ROCK1	LNPEP	0.807618454	3.77E-37
TGCT	IUPHAR	ROCK1	DPP8	0.815418328	2.15E-38
TGCT	IUPHAR	ROCK1	NCOA2	0.838605986	1.80E-42
TGCT	IUPHAR	ROCK1	ERN1	0.869045486	6.32E-49
TGCT	IUPHAR	ROCK1	IL6ST	0.882691281	2.28E-52
TGCT	IUPHAR	ROCK1	HIPK3	0.895017513	7.20E-56
TGCT	Kinase	ROCK1	ERN1	0.869045486	6.32E-49
TGCT	Kinase	ROCK1	HIPK3	0.895017513	7.20E-56
TGCT	TF	ROCK1	ZNF641	0.802135444	2.62E-36
TGCT	TF	ROCK1	NFATC2	0.805184151	8.98E-37
TGCT	TF	ROCK1	ELK3	0.807613672	3.78E-37
TGCT	TF	ROCK1	REL	0.837763049	2.60E-42
TGCT	TF	ROCK1	NCOA2	0.838605986	1.80E-42
TGCT	TF	ROCK1	ZNF699	0.84357409	1.99E-43
TGCT	TSG	ROCK1	NFATC2	0.805184151	8.98E-37
TGCT	TSG	ROCK1	RNF111	0.813844343	3.87E-38
THCA	Cell metabolism gene	ROCK1	MGAT5	0.801963649	1.20E-129
THCA	Cell metabolism gene	ROCK1	SPTLC2	0.809835264	3.93E-134
THCA	Cell metabolism gene	ROCK1	IPMK	0.81204093	1.99E-135
THCA	Cell metabolism gene	ROCK1	PAFAH1B2	0.816224714	6.26E-138
THCA	Cell metabolism gene	ROCK1	SYNJ2	0.823297289	2.61E-142
THCA	Cell metabolism gene	ROCK1	NCOA2	0.841303228	2.09E-154
THCA	Cell metabolism gene	ROCK1	UGCG	0.869169504	1.85E-176
THCA	Cell metabolism gene	ROCK1	PIK3CA	0.920686539	4.56E-235
THCA	CGC	ROCK1	KDM5A	0.811247491	5.85E-135
THCA	CGC	ROCK1	REL	0.811861573	2.54E-135
THCA	CGC	ROCK1	EGFR	0.812145431	1.73E-135
THCA	CGC	ROCK1	PAFAH1B2	0.816224714	6.26E-138
THCA	CGC	ROCK1	BARD1	0.817390012	1.23E-138
THCA	CGC	ROCK1	UBR5	0.820357889	1.82E-140
THCA	CGC	ROCK1	MAML2	0.828666731	9.08E-146
THCA	CGC	ROCK1	IL6ST	0.839146478	7.05E-153
THCA	CGC	ROCK1	NCOA2	0.841303228	2.09E-154
THCA	CGC	ROCK1	LATS1	0.844104363	2.01E-156
THCA	CGC	ROCK1	ASXL2	0.845160993	3.41E-157
THCA	CGC	ROCK1	STRN	0.867841528	2.69E-175
THCA	CGC	ROCK1	PIK3CA	0.920686539	4.56E-235
THCA	Epifactor	ROCK1	DDX21	0.809383218	7.20E-134
THCA	Epifactor	ROCK1	ATF7IP	0.810305916	2.09E-134
THCA	Epifactor	ROCK1	KDM5A	0.811247491	5.85E-135
THCA	Epifactor	ROCK1	PPP4R2	0.81296349	5.67E-136
THCA	Epifactor	ROCK1	BARD1	0.817390012	1.23E-138
THCA	Epifactor	ROCK1	UBR5	0.820357889	1.82E-140
THCA	Epifactor	ROCK1	MAP3K7	0.827945229	2.69E-145
THCA	Epifactor	ROCK1	REST	0.828261177	1.67E-145
THCA	Epifactor	ROCK1	NCOA2	0.841303228	2.09E-154
THCA	Epifactor	ROCK1	ASXL2	0.845160993	3.41E-157
THCA	Epifactor	ROCK1	RSF1	0.846496121	3.54E-158
THCA	IUPHAR	ROCK1	HIPK3	0.804241949	6.34E-131
THCA	IUPHAR	ROCK1	SCYL2	0.805641286	1.02E-131
THCA	IUPHAR	ROCK1	TAOK1	0.806146893	5.26E-132
THCA	IUPHAR	ROCK1	WNK1	0.809780771	4.23E-134
THCA	IUPHAR	ROCK1	SPTLC2	0.809835264	3.93E-134
THCA	IUPHAR	ROCK1	KDM5A	0.811247491	5.85E-135
THCA	IUPHAR	ROCK1	EGFR	0.812145431	1.73E-135
THCA	IUPHAR	ROCK1	LNPEP	0.816157996	6.87E-138
THCA	IUPHAR	ROCK1	SYNJ2	0.823297289	2.61E-142
THCA	IUPHAR	ROCK1	SAMD8	0.826984622	1.13E-144
THCA	IUPHAR	ROCK1	MAP3K7	0.827945229	2.69E-145
THCA	IUPHAR	ROCK1	MAP3K2	0.829745313	1.77E-146
THCA	IUPHAR	ROCK1	IL6ST	0.839146478	7.05E-153
THCA	IUPHAR	ROCK1	NCOA2	0.841303228	2.09E-154
THCA	IUPHAR	ROCK1	LATS1	0.844104363	2.01E-156
THCA	IUPHAR	ROCK1	ATP11B	0.853060072	3.77E-163
THCA	IUPHAR	ROCK1	UGCG	0.869169504	1.85E-176
THCA	IUPHAR	ROCK1	NIPAL2	0.874354113	4.00E-181
THCA	IUPHAR	ROCK1	PIK3CA	0.920686539	4.56E-235
THCA	Kinase	ROCK1	HIPK3	0.804241949	6.34E-131
THCA	Kinase	ROCK1	SCYL2	0.805641286	1.02E-131
THCA	Kinase	ROCK1	TAOK1	0.806146893	5.26E-132
THCA	Kinase	ROCK1	WNK1	0.809780771	4.23E-134
THCA	Kinase	ROCK1	EGFR	0.812145431	1.73E-135
THCA	Kinase	ROCK1	MAP3K7	0.827945229	2.69E-145
THCA	Kinase	ROCK1	MAP3K2	0.829745313	1.77E-146
THCA	Kinase	ROCK1	LATS1	0.844104363	2.01E-156
THCA	TF	ROCK1	SKIL	0.803315948	2.10E-130
THCA	TF	ROCK1	BACH1	0.807906717	5.15E-133
THCA	TF	ROCK1	REL	0.811861573	2.54E-135
THCA	TF	ROCK1	ELK3	0.821930325	1.90E-141
THCA	TF	ROCK1	REST	0.828261177	1.67E-145
THCA	TF	ROCK1	ZNF430	0.838925359	1.01E-152
THCA	TF	ROCK1	NCOA2	0.841303228	2.09E-154
THCA	TSG	ROCK1	SMCHD1	0.802911182	3.55E-130
THCA	TSG	ROCK1	SKIL	0.803315948	2.10E-130
THCA	TSG	ROCK1	KDM5A	0.811247491	5.85E-135
THCA	TSG	ROCK1	BARD1	0.817390012	1.23E-138
THCA	TSG	ROCK1	ANAPC1	0.827477655	5.43E-145
THCA	TSG	ROCK1	LATS1	0.844104363	2.01E-156
THYM	Cell metabolism gene	ROCK1	POLR2B	0.80106951	1.62E-28
THYM	Cell metabolism gene	ROCK1	NUPL1	0.808897137	1.87E-29
THYM	Cell metabolism gene	ROCK1	PDP2	0.808906255	1.87E-29
THYM	Cell metabolism gene	ROCK1	ACER2	0.809311779	1.67E-29
THYM	Cell metabolism gene	ROCK1	GLS	0.810094856	1.33E-29
THYM	Cell metabolism gene	ROCK1	NCOA1	0.811546725	8.82E-30
THYM	Cell metabolism gene	ROCK1	RANBP2	0.813258391	5.39E-30
THYM	Cell metabolism gene	ROCK1	MED23	0.817146941	1.73E-30
THYM	Cell metabolism gene	ROCK1	NEU3	0.817403838	1.60E-30
THYM	Cell metabolism gene	ROCK1	MANEA	0.820922825	5.56E-31
THYM	Cell metabolism gene	ROCK1	EDEM3	0.821356991	4.88E-31
THYM	Cell metabolism gene	ROCK1	DCP1A	0.823310215	2.68E-31
THYM	Cell metabolism gene	ROCK1	EP300	0.82550844	1.36E-31
THYM	Cell metabolism gene	ROCK1	MED12	0.831241276	2.19E-32
THYM	Cell metabolism gene	ROCK1	CREBBP	0.838146272	2.22E-33
THYM	Cell metabolism gene	ROCK1	MED14	0.83840873	2.03E-33
THYM	Cell metabolism gene	ROCK1	SYNJ2	0.839511604	1.40E-33
THYM	Cell metabolism gene	ROCK1	UPF2	0.842257196	5.40E-34
THYM	Cell metabolism gene	ROCK1	PIKFYVE	0.842339151	5.25E-34
THYM	Cell metabolism gene	ROCK1	NCOR1	0.842890968	4.33E-34
THYM	Cell metabolism gene	ROCK1	MTMR6	0.843741596	3.21E-34
THYM	Cell metabolism gene	ROCK1	FBXW2	0.846166613	1.35E-34
THYM	Cell metabolism gene	ROCK1	PIK3CA	0.847852081	7.37E-35
THYM	Cell metabolism gene	ROCK1	MED1	0.873258267	2.82E-39
THYM	Cell metabolism gene	ROCK1	MED13L	0.893902475	1.24E-43
THYM	Cell metabolism gene	ROCK1	SEC24B	0.895429094	5.44E-44
THYM	Cell metabolism gene	ROCK1	NUP153	0.897539005	1.71E-44
THYM	Cell metabolism gene	ROCK1	MAN2A1	0.906651556	8.43E-47
THYM	Cell metabolism gene	ROCK1	SMG1	0.910889672	5.90E-48
THYM	CGC	ROCK1	SPEN	0.800965066	1.67E-28
THYM	CGC	ROCK1	SETD1B	0.801237936	1.55E-28
THYM	CGC	ROCK1	WRN	0.803760944	7.80E-29
THYM	CGC	ROCK1	VHL	0.807057837	3.14E-29
THYM	CGC	ROCK1	LATS1	0.811067006	1.01E-29
THYM	CGC	ROCK1	MLLT10	0.811381118	9.25E-30
THYM	CGC	ROCK1	NCOA1	0.811546725	8.82E-30
THYM	CGC	ROCK1	RANBP2	0.813258391	5.39E-30
THYM	CGC	ROCK1	TRIM33	0.821155116	5.18E-31
THYM	CGC	ROCK1	ZMYM2	0.823765009	2.33E-31
THYM	CGC	ROCK1	PPM1D	0.824104258	2.10E-31
THYM	CGC	ROCK1	EP300	0.82550844	1.36E-31
THYM	CGC	ROCK1	NSD1	0.825935019	1.19E-31
THYM	CGC	ROCK1	FUBP1	0.828794104	4.81E-32
THYM	CGC	ROCK1	MED12	0.831241276	2.19E-32
THYM	CGC	ROCK1	BRD3	0.836149263	4.36E-33
THYM	CGC	ROCK1	CREBBP	0.838146272	2.22E-33
THYM	CGC	ROCK1	CBL	0.840047916	1.16E-33
THYM	CGC	ROCK1	ATRX	0.84023532	1.09E-33
THYM	CGC	ROCK1	GOPC	0.841606916	6.77E-34
THYM	CGC	ROCK1	NCOR1	0.842890968	4.33E-34
THYM	CGC	ROCK1	PBRM1	0.843169668	3.92E-34
THYM	CGC	ROCK1	PIK3CA	0.847852081	7.37E-35
THYM	CGC	ROCK1	SETD2	0.853241238	1.00E-35
THYM	CGC	ROCK1	UBR5	0.859713578	8.19E-37
THYM	CGC	ROCK1	PTPN11	0.860171194	6.83E-37
THYM	CGC	ROCK1	BARD1	0.860986432	4.93E-37
THYM	CGC	ROCK1	STAG1	0.867226967	3.81E-38
THYM	CGC	ROCK1	ATF1	0.876055724	8.06E-40
THYM	CGC	ROCK1	STRN	0.883417153	2.57E-41
THYM	CGC	ROCK1	BIRC6	0.897220596	2.04E-44
THYM	CGC	ROCK1	BCLAF1	0.899396659	6.03E-45
THYM	CGC	ROCK1	SF3B1	0.902259303	1.16E-45
THYM	CGC	ROCK1	TRRAP	0.904723648	2.71E-46
THYM	CGC	ROCK1	ARID1A	0.905191786	2.05E-46
THYM	CGC	ROCK1	N4BP2	0.919566561	1.64E-50
THYM	CGC	ROCK1	CREB1	0.934349516	1.31E-55
THYM	Epifactor	ROCK1	SPEN	0.800965066	1.67E-28
THYM	Epifactor	ROCK1	MBTD1	0.801122225	1.60E-28
THYM	Epifactor	ROCK1	SETD1B	0.801237936	1.55E-28
THYM	Epifactor	ROCK1	RNF168	0.802647665	1.06E-28
THYM	Epifactor	ROCK1	CHD9	0.803202523	9.09E-29
THYM	Epifactor	ROCK1	TET3	0.804442219	6.47E-29
THYM	Epifactor	ROCK1	RCOR1	0.806687097	3.48E-29
THYM	Epifactor	ROCK1	BRWD1	0.807067416	3.13E-29
THYM	Epifactor	ROCK1	WHSC1L1	0.807680404	2.64E-29
THYM	Epifactor	ROCK1	SUV420H1	0.807763076	2.58E-29
THYM	Epifactor	ROCK1	PHF8	0.808956818	1.84E-29
THYM	Epifactor	ROCK1	PHF20L1	0.809502407	1.58E-29
THYM	Epifactor	ROCK1	TP53BP1	0.809893729	1.41E-29
THYM	Epifactor	ROCK1	PHF2	0.810901847	1.06E-29
THYM	Epifactor	ROCK1	MLLT10	0.811381118	9.25E-30
THYM	Epifactor	ROCK1	NCOA1	0.811546725	8.82E-30
THYM	Epifactor	ROCK1	IKZF3	0.812413036	6.88E-30
THYM	Epifactor	ROCK1	SENP1	0.817196465	1.70E-30
THYM	Epifactor	ROCK1	HCFC2	0.819282319	9.13E-31
THYM	Epifactor	ROCK1	ATXN7	0.820764598	5.84E-31
THYM	Epifactor	ROCK1	TRIM33	0.821155116	5.18E-31
THYM	Epifactor	ROCK1	DR1	0.821726869	4.36E-31
THYM	Epifactor	ROCK1	SIRT1	0.822523722	3.42E-31
THYM	Epifactor	ROCK1	ZMYM2	0.823765009	2.33E-31
THYM	Epifactor	ROCK1	EP300	0.82550844	1.36E-31
THYM	Epifactor	ROCK1	NSD1	0.825935019	1.19E-31
THYM	Epifactor	ROCK1	EPC1	0.829271044	4.13E-32
THYM	Epifactor	ROCK1	PHC3	0.830422782	2.86E-32
THYM	Epifactor	ROCK1	HMG20A	0.830820033	2.51E-32
THYM	Epifactor	ROCK1	STK4	0.833379167	1.09E-32
THYM	Epifactor	ROCK1	EPC2	0.834509245	7.52E-33
THYM	Epifactor	ROCK1	SMEK2	0.834646842	7.18E-33
THYM	Epifactor	ROCK1	BRD3	0.836149263	4.36E-33
THYM	Epifactor	ROCK1	CDK17	0.836564946	3.79E-33
THYM	Epifactor	ROCK1	PPP4R2	0.836777391	3.53E-33
THYM	Epifactor	ROCK1	SHPRH	0.836980417	3.30E-33
THYM	Epifactor	ROCK1	CREBBP	0.838146272	2.22E-33
THYM	Epifactor	ROCK1	CTR9	0.838148187	2.22E-33
THYM	Epifactor	ROCK1	ATRX	0.84023532	1.09E-33
THYM	Epifactor	ROCK1	NCOR1	0.842890968	4.33E-34
THYM	Epifactor	ROCK1	PBRM1	0.843169668	3.92E-34
THYM	Epifactor	ROCK1	WAC	0.84485302	2.17E-34
THYM	Epifactor	ROCK1	BAZ2A	0.845676749	1.61E-34
THYM	Epifactor	ROCK1	USP49	0.846548087	1.18E-34
THYM	Epifactor	ROCK1	MBD5	0.846549065	1.18E-34
THYM	Epifactor	ROCK1	BRPF3	0.846771998	1.09E-34
THYM	Epifactor	ROCK1	KDM3A	0.84866636	5.48E-35
THYM	Epifactor	ROCK1	SETD2	0.853241238	1.00E-35
THYM	Epifactor	ROCK1	SMARCAD1	0.857171897	2.22E-36
THYM	Epifactor	ROCK1	MGA	0.857254605	2.15E-36
THYM	Epifactor	ROCK1	RSF1	0.857892247	1.68E-36
THYM	Epifactor	ROCK1	UBR5	0.859713578	8.19E-37
THYM	Epifactor	ROCK1	BARD1	0.860986432	4.93E-37
THYM	Epifactor	ROCK1	REST	0.86365758	1.67E-37
THYM	Epifactor	ROCK1	MAP3K7	0.867217724	3.82E-38
THYM	Epifactor	ROCK1	UBR2	0.868043538	2.70E-38
THYM	Epifactor	ROCK1	ATAD2B	0.87150114	6.10E-39
THYM	Epifactor	ROCK1	ATF2	0.874903646	1.35E-39
THYM	Epifactor	ROCK1	SMARCA5	0.886624247	5.31E-42
THYM	Epifactor	ROCK1	ARID4A	0.894938484	7.10E-44
THYM	Epifactor	ROCK1	NIPBL	0.896521791	3.00E-44
THYM	Epifactor	ROCK1	SF3B1	0.902259303	1.16E-45
THYM	Epifactor	ROCK1	TRRAP	0.904723648	2.71E-46
THYM	Epifactor	ROCK1	ARID1A	0.905191786	2.05E-46
THYM	Epifactor	ROCK1	BPTF	0.90914982	1.79E-47
THYM	Epifactor	ROCK1	C11orf30	0.931277789	1.85E-54
THYM	IUPHAR	ROCK1	SETD1B	0.801237936	1.55E-28
THYM	IUPHAR	ROCK1	SLC10A7	0.80207345	1.24E-28
THYM	IUPHAR	ROCK1	WNK1	0.802975393	9.67E-29
THYM	IUPHAR	ROCK1	SLC25A40	0.803792057	7.74E-29
THYM	IUPHAR	ROCK1	IL17RA	0.804868754	5.76E-29
THYM	IUPHAR	ROCK1	BRWD1	0.807067416	3.13E-29
THYM	IUPHAR	ROCK1	TPP2	0.807140424	3.07E-29
THYM	IUPHAR	ROCK1	PHF8	0.808956818	1.84E-29
THYM	IUPHAR	ROCK1	NEK1	0.809142264	1.75E-29
THYM	IUPHAR	ROCK1	ACER2	0.809311779	1.67E-29
THYM	IUPHAR	ROCK1	BIRC2	0.809475371	1.59E-29
THYM	IUPHAR	ROCK1	DYRK1A	0.809813856	1.45E-29
THYM	IUPHAR	ROCK1	GLS	0.810094856	1.33E-29
THYM	IUPHAR	ROCK1	PHF2	0.810901847	1.06E-29
THYM	IUPHAR	ROCK1	LATS1	0.811067006	1.01E-29
THYM	IUPHAR	ROCK1	NCOA1	0.811546725	8.82E-30
THYM	IUPHAR	ROCK1	SLC4A7	0.812550258	6.61E-30
THYM	IUPHAR	ROCK1	SENP1	0.817196465	1.70E-30
THYM	IUPHAR	ROCK1	SENP7	0.817593099	1.51E-30
THYM	IUPHAR	ROCK1	ERN1	0.818108894	1.30E-30
THYM	IUPHAR	ROCK1	TRIM33	0.821155116	5.18E-31
THYM	IUPHAR	ROCK1	SIRT1	0.822523722	3.42E-31
THYM	IUPHAR	ROCK1	SLC30A7	0.822658002	3.28E-31
THYM	IUPHAR	ROCK1	PPM1D	0.824104258	2.10E-31
THYM	IUPHAR	ROCK1	EP300	0.82550844	1.36E-31
THYM	IUPHAR	ROCK1	NSD1	0.825935019	1.19E-31
THYM	IUPHAR	ROCK1	STK4	0.833379167	1.09E-32
THYM	IUPHAR	ROCK1	NR2C2	0.833773356	9.59E-33
THYM	IUPHAR	ROCK1	BRD3	0.836149263	4.36E-33
THYM	IUPHAR	ROCK1	CDK17	0.836564946	3.79E-33
THYM	IUPHAR	ROCK1	CREBBP	0.838146272	2.22E-33
THYM	IUPHAR	ROCK1	SYNJ2	0.839511604	1.40E-33
THYM	IUPHAR	ROCK1	PIKFYVE	0.842339151	5.25E-34
THYM	IUPHAR	ROCK1	PBRM1	0.843169668	3.92E-34
THYM	IUPHAR	ROCK1	BAZ2A	0.845676749	1.61E-34
THYM	IUPHAR	ROCK1	DPP8	0.846538903	1.19E-34
THYM	IUPHAR	ROCK1	BRPF3	0.846771998	1.09E-34
THYM	IUPHAR	ROCK1	PIK3CA	0.847852081	7.37E-35
THYM	IUPHAR	ROCK1	KDM3A	0.84866636	5.48E-35
THYM	IUPHAR	ROCK1	SETD2	0.853241238	1.00E-35
THYM	IUPHAR	ROCK1	SLC35A3	0.860148847	6.89E-37
THYM	IUPHAR	ROCK1	SLC25A46	0.866104987	6.09E-38
THYM	IUPHAR	ROCK1	MAP3K7	0.867217724	3.82E-38
THYM	IUPHAR	ROCK1	SCYL2	0.871209578	6.93E-39
THYM	IUPHAR	ROCK1	TNKS2	0.871428756	6.30E-39
THYM	IUPHAR	ROCK1	ATAD2B	0.87150114	6.10E-39
THYM	IUPHAR	ROCK1	SLC12A6	0.881840569	5.47E-41
THYM	IUPHAR	ROCK1	BIRC6	0.897220596	2.04E-44
THYM	IUPHAR	ROCK1	HIPK1	0.900638461	2.97E-45
THYM	IUPHAR	ROCK1	ADAM10	0.904283192	3.53E-46
THYM	IUPHAR	ROCK1	TRRAP	0.904723648	2.71E-46
THYM	IUPHAR	ROCK1	BPTF	0.90914982	1.79E-47
THYM	IUPHAR	ROCK1	SMG1	0.910889672	5.90E-48
THYM	IUPHAR	ROCK1	PRPF4B	0.918614435	3.23E-50
THYM	Kinase	ROCK1	WNK1	0.802975393	9.67E-29
THYM	Kinase	ROCK1	NEK1	0.809142264	1.75E-29
THYM	Kinase	ROCK1	DYRK1A	0.809813856	1.45E-29
THYM	Kinase	ROCK1	LATS1	0.811067006	1.01E-29
THYM	Kinase	ROCK1	ERN1	0.818108894	1.30E-30
THYM	Kinase	ROCK1	TRIM33	0.821155116	5.18E-31
THYM	Kinase	ROCK1	STK4	0.833379167	1.09E-32
THYM	Kinase	ROCK1	BRD3	0.836149263	4.36E-33
THYM	Kinase	ROCK1	CDK17	0.836564946	3.79E-33
THYM	Kinase	ROCK1	MAP3K7	0.867217724	3.82E-38
THYM	Kinase	ROCK1	SCYL2	0.871209578	6.93E-39
THYM	Kinase	ROCK1	HIPK1	0.900638461	2.97E-45
THYM	Kinase	ROCK1	TRRAP	0.904723648	2.71E-46
THYM	Kinase	ROCK1	SMG1	0.910889672	5.90E-48
THYM	Kinase	ROCK1	PRPF4B	0.918614435	3.23E-50
THYM	TF	ROCK1	ZNF417	0.800185825	2.06E-28
THYM	TF	ROCK1	ZNF254	0.800751686	1.77E-28
THYM	TF	ROCK1	HIVEP2	0.800810034	1.74E-28
THYM	TF	ROCK1	SPEN	0.800965066	1.67E-28
THYM	TF	ROCK1	ZNF445	0.801807384	1.33E-28
THYM	TF	ROCK1	TET3	0.804442219	6.47E-29
THYM	TF	ROCK1	ZNF654	0.805414523	4.95E-29
THYM	TF	ROCK1	JRKL	0.810198742	1.30E-29
THYM	TF	ROCK1	ZSCAN12	0.810991338	1.03E-29
THYM	TF	ROCK1	NCOA1	0.811546725	8.82E-30
THYM	TF	ROCK1	KLF12	0.811985673	7.78E-30
THYM	TF	ROCK1	IKZF3	0.812413036	6.88E-30
THYM	TF	ROCK1	ZNF236	0.813082587	5.67E-30
THYM	TF	ROCK1	RFX3	0.814608697	3.64E-30
THYM	TF	ROCK1	ZNF234	0.815056807	3.19E-30
THYM	TF	ROCK1	ZNF510	0.815646269	2.69E-30
THYM	TF	ROCK1	ZBTB10	0.818959366	1.01E-30
THYM	TF	ROCK1	ZBTB44	0.821436831	4.76E-31
THYM	TF	ROCK1	TMF1	0.821539721	4.61E-31
THYM	TF	ROCK1	DR1	0.821726869	4.36E-31
THYM	TF	ROCK1	ZNF570	0.824403689	1.91E-31
THYM	TF	ROCK1	KLF7	0.828029484	6.14E-32
THYM	TF	ROCK1	ZNF148	0.829056447	4.43E-32
THYM	TF	ROCK1	HMG20A	0.830820033	2.51E-32
THYM	TF	ROCK1	ZNF281	0.830940572	2.42E-32
THYM	TF	ROCK1	FOXJ3	0.832090125	1.66E-32
THYM	TF	ROCK1	NR2C2	0.833773356	9.59E-33
THYM	TF	ROCK1	ZNF675	0.833954182	9.03E-33
THYM	TF	ROCK1	SP2	0.836394473	4.01E-33
THYM	TF	ROCK1	CREBZF	0.839520207	1.39E-33
THYM	TF	ROCK1	ZNF225	0.8418809	6.16E-34
THYM	TF	ROCK1	ZNF776	0.84215692	5.59E-34
THYM	TF	ROCK1	ZNF430	0.845046702	2.02E-34
THYM	TF	ROCK1	BAZ2A	0.845676749	1.61E-34
THYM	TF	ROCK1	ZFX	0.848526224	5.77E-35
THYM	TF	ROCK1	ZBTB39	0.849344443	4.28E-35
THYM	TF	ROCK1	ZNF518A	0.851568967	1.88E-35
THYM	TF	ROCK1	ZNF765	0.853673616	8.52E-36
THYM	TF	ROCK1	ZNF813	0.855197265	4.77E-36
THYM	TF	ROCK1	ZBTB34	0.857183566	2.21E-36
THYM	TF	ROCK1	MGA	0.857254605	2.15E-36
THYM	TF	ROCK1	ZNF397	0.861576952	3.89E-37
THYM	TF	ROCK1	ZNF611	0.862577228	2.60E-37
THYM	TF	ROCK1	ZNF407	0.86349003	1.79E-37
THYM	TF	ROCK1	REST	0.86365758	1.67E-37
THYM	TF	ROCK1	ZNF701	0.864502226	1.18E-37
THYM	TF	ROCK1	ZNF431	0.865808105	6.89E-38
THYM	TF	ROCK1	ELF1	0.87396264	2.06E-39
THYM	TF	ROCK1	ATF2	0.874903646	1.35E-39
THYM	TF	ROCK1	FOXN2	0.875170895	1.20E-39
THYM	TF	ROCK1	ATF1	0.876055724	8.06E-40
THYM	TF	ROCK1	SON	0.877910896	3.45E-40
THYM	TF	ROCK1	ZBTB11	0.882469127	4.05E-41
THYM	TF	ROCK1	ZNF800	0.886910635	4.60E-42
THYM	TF	ROCK1	SP3	0.888465306	2.10E-42
THYM	TF	ROCK1	ZNF644	0.891236542	5.06E-43
THYM	TF	ROCK1	RLF	0.891935417	3.51E-43
THYM	TF	ROCK1	ZFP91	0.901053778	2.34E-45
THYM	TF	ROCK1	BPTF	0.90914982	1.79E-47
THYM	TF	ROCK1	ZNF292	0.910577469	7.21E-48
THYM	TF	ROCK1	SP4	0.914407314	5.86E-49
THYM	TF	ROCK1	ZNF318	0.919961818	1.24E-50
THYM	TF	ROCK1	CREB1	0.934349516	1.31E-55
THYM	TSG	ROCK1	VHL	0.807057837	3.14E-29
THYM	TSG	ROCK1	WHSC1L1	0.807680404	2.64E-29
THYM	TSG	ROCK1	USP33	0.808883032	1.88E-29
THYM	TSG	ROCK1	TP53BP1	0.809893729	1.41E-29
THYM	TSG	ROCK1	PDS5B	0.810340254	1.24E-29
THYM	TSG	ROCK1	LATS1	0.811067006	1.01E-29
THYM	TSG	ROCK1	ANAPC1	0.812089479	7.55E-30
THYM	TSG	ROCK1	IKZF3	0.812413036	6.88E-30
THYM	TSG	ROCK1	IGF2R	0.814967791	3.28E-30
THYM	TSG	ROCK1	SIRT1	0.822523722	3.42E-31
THYM	TSG	ROCK1	RB1CC1	0.827881079	6.43E-32
THYM	TSG	ROCK1	PHC3	0.830422782	2.86E-32
THYM	TSG	ROCK1	NR2C2	0.833773356	9.59E-33
THYM	TSG	ROCK1	SHPRH	0.836980417	3.30E-33
THYM	TSG	ROCK1	CREBBP	0.838146272	2.22E-33
THYM	TSG	ROCK1	DIDO1	0.838669209	1.86E-33
THYM	TSG	ROCK1	CBL	0.840047916	1.16E-33
THYM	TSG	ROCK1	PBRM1	0.843169668	3.92E-34
THYM	TSG	ROCK1	RBL1	0.844139197	2.79E-34
THYM	TSG	ROCK1	KDM3A	0.84866636	5.48E-35
THYM	TSG	ROCK1	RBL2	0.848699838	5.42E-35
THYM	TSG	ROCK1	SETD2	0.853241238	1.00E-35
THYM	TSG	ROCK1	PTPN11	0.860171194	6.83E-37
THYM	TSG	ROCK1	BARD1	0.860986432	4.93E-37
THYM	TSG	ROCK1	HACE1	0.872774987	3.49E-39
THYM	TSG	ROCK1	SMCHD1	0.900166219	3.89E-45
THYM	TSG	ROCK1	ARID1A	0.905191786	2.05E-46
THYM	TSG	ROCK1	ZNF292	0.910577469	7.21E-48
UCEC	CGC	ROCK1	IL6ST	0.818269452	9.71E-50
UCEC	Epifactor	ROCK1	JMJD1C	0.804410166	6.91E-47
UCEC	Epifactor	ROCK1	ATF2	0.814634231	5.73E-49
UCEC	Epifactor	ROCK1	USP12	0.832666788	5.67E-53
UCEC	IUPHAR	ROCK1	JMJD1C	0.804410166	6.91E-47
UCEC	IUPHAR	ROCK1	IL6ST	0.818269452	9.71E-50
UCEC	IUPHAR	ROCK1	HIPK3	0.827126467	1.08E-51
UCEC	Kinase	ROCK1	HIPK3	0.827126467	1.08E-51
UCEC	TF	ROCK1	ATF2	0.814634231	5.73E-49
UCEC	TSG	ROCK1	USP12	0.832666788	5.67E-53
UCS	Cell metabolism gene	ROCK1	POLR2B	0.80106951	1.62E-28
UCS	Cell metabolism gene	ROCK1	NUPL1	0.808897137	1.87E-29
UCS	Cell metabolism gene	ROCK1	PDP2	0.808906255	1.87E-29
UCS	Cell metabolism gene	ROCK1	ACER2	0.809311779	1.67E-29
UCS	Cell metabolism gene	ROCK1	GLS	0.810094856	1.33E-29
UCS	Cell metabolism gene	ROCK1	NCOA1	0.811546725	8.82E-30
UCS	Cell metabolism gene	ROCK1	RANBP2	0.813258391	5.39E-30
UCS	Cell metabolism gene	ROCK1	MED23	0.817146941	1.73E-30
UCS	Cell metabolism gene	ROCK1	NEU3	0.817403838	1.60E-30
UCS	Cell metabolism gene	ROCK1	MANEA	0.820922825	5.56E-31
UCS	Cell metabolism gene	ROCK1	EDEM3	0.821356991	4.88E-31
UCS	Cell metabolism gene	ROCK1	DCP1A	0.823310215	2.68E-31
UCS	Cell metabolism gene	ROCK1	EP300	0.82550844	1.36E-31
UCS	Cell metabolism gene	ROCK1	MED12	0.831241276	2.19E-32
UCS	Cell metabolism gene	ROCK1	CREBBP	0.838146272	2.22E-33
UCS	Cell metabolism gene	ROCK1	MED14	0.83840873	2.03E-33
UCS	Cell metabolism gene	ROCK1	SYNJ2	0.839511604	1.40E-33
UCS	Cell metabolism gene	ROCK1	UPF2	0.842257196	5.40E-34
UCS	Cell metabolism gene	ROCK1	PIKFYVE	0.842339151	5.25E-34
UCS	Cell metabolism gene	ROCK1	NCOR1	0.842890968	4.33E-34
UCS	Cell metabolism gene	ROCK1	MTMR6	0.843741596	3.21E-34
UCS	Cell metabolism gene	ROCK1	FBXW2	0.846166613	1.35E-34
UCS	Cell metabolism gene	ROCK1	PIK3CA	0.847852081	7.37E-35
UCS	Cell metabolism gene	ROCK1	MED1	0.873258267	2.82E-39
UCS	Cell metabolism gene	ROCK1	MED13L	0.893902475	1.24E-43
UCS	Cell metabolism gene	ROCK1	SEC24B	0.895429094	5.44E-44
UCS	Cell metabolism gene	ROCK1	NUP153	0.897539005	1.71E-44
UCS	Cell metabolism gene	ROCK1	MAN2A1	0.906651556	8.43E-47
UCS	Cell metabolism gene	ROCK1	SMG1	0.910889672	5.90E-48
UCS	CGC	ROCK1	SPEN	0.800965066	1.67E-28
UCS	CGC	ROCK1	SETD1B	0.801237936	1.55E-28
UCS	CGC	ROCK1	WRN	0.803760944	7.80E-29
UCS	CGC	ROCK1	VHL	0.807057837	3.14E-29
UCS	CGC	ROCK1	LATS1	0.811067006	1.01E-29
UCS	CGC	ROCK1	MLLT10	0.811381118	9.25E-30
UCS	CGC	ROCK1	NCOA1	0.811546725	8.82E-30
UCS	CGC	ROCK1	RANBP2	0.813258391	5.39E-30
UCS	CGC	ROCK1	TRIM33	0.821155116	5.18E-31
UCS	CGC	ROCK1	ZMYM2	0.823765009	2.33E-31
UCS	CGC	ROCK1	PPM1D	0.824104258	2.10E-31
UCS	CGC	ROCK1	EP300	0.82550844	1.36E-31
UCS	CGC	ROCK1	NSD1	0.825935019	1.19E-31
UCS	CGC	ROCK1	FUBP1	0.828794104	4.81E-32
UCS	CGC	ROCK1	MED12	0.831241276	2.19E-32
UCS	CGC	ROCK1	BRD3	0.836149263	4.36E-33
UCS	CGC	ROCK1	CREBBP	0.838146272	2.22E-33
UCS	CGC	ROCK1	CBL	0.840047916	1.16E-33
UCS	CGC	ROCK1	ATRX	0.84023532	1.09E-33
UCS	CGC	ROCK1	GOPC	0.841606916	6.77E-34
UCS	CGC	ROCK1	NCOR1	0.842890968	4.33E-34
UCS	CGC	ROCK1	PBRM1	0.843169668	3.92E-34
UCS	CGC	ROCK1	PIK3CA	0.847852081	7.37E-35
UCS	CGC	ROCK1	SETD2	0.853241238	1.00E-35
UCS	CGC	ROCK1	UBR5	0.859713578	8.19E-37
UCS	CGC	ROCK1	PTPN11	0.860171194	6.83E-37
UCS	CGC	ROCK1	BARD1	0.860986432	4.93E-37
UCS	CGC	ROCK1	STAG1	0.867226967	3.81E-38
UCS	CGC	ROCK1	ATF1	0.876055724	8.06E-40
UCS	CGC	ROCK1	STRN	0.883417153	2.57E-41
UCS	CGC	ROCK1	BIRC6	0.897220596	2.04E-44
UCS	CGC	ROCK1	BCLAF1	0.899396659	6.03E-45
UCS	CGC	ROCK1	SF3B1	0.902259303	1.16E-45
UCS	CGC	ROCK1	TRRAP	0.904723648	2.71E-46
UCS	CGC	ROCK1	ARID1A	0.905191786	2.05E-46
UCS	CGC	ROCK1	N4BP2	0.919566561	1.64E-50
UCS	CGC	ROCK1	CREB1	0.934349516	1.31E-55
UCS	Epifactor	ROCK1	SPEN	0.800965066	1.67E-28
UCS	Epifactor	ROCK1	MBTD1	0.801122225	1.60E-28
UCS	Epifactor	ROCK1	SETD1B	0.801237936	1.55E-28
UCS	Epifactor	ROCK1	RNF168	0.802647665	1.06E-28
UCS	Epifactor	ROCK1	CHD9	0.803202523	9.09E-29
UCS	Epifactor	ROCK1	TET3	0.804442219	6.47E-29
UCS	Epifactor	ROCK1	RCOR1	0.806687097	3.48E-29
UCS	Epifactor	ROCK1	BRWD1	0.807067416	3.13E-29
UCS	Epifactor	ROCK1	WHSC1L1	0.807680404	2.64E-29
UCS	Epifactor	ROCK1	SUV420H1	0.807763076	2.58E-29
UCS	Epifactor	ROCK1	PHF8	0.808956818	1.84E-29
UCS	Epifactor	ROCK1	PHF20L1	0.809502407	1.58E-29
UCS	Epifactor	ROCK1	TP53BP1	0.809893729	1.41E-29
UCS	Epifactor	ROCK1	PHF2	0.810901847	1.06E-29
UCS	Epifactor	ROCK1	MLLT10	0.811381118	9.25E-30
UCS	Epifactor	ROCK1	NCOA1	0.811546725	8.82E-30
UCS	Epifactor	ROCK1	IKZF3	0.812413036	6.88E-30
UCS	Epifactor	ROCK1	SENP1	0.817196465	1.70E-30
UCS	Epifactor	ROCK1	HCFC2	0.819282319	9.13E-31
UCS	Epifactor	ROCK1	ATXN7	0.820764598	5.84E-31
UCS	Epifactor	ROCK1	TRIM33	0.821155116	5.18E-31
UCS	Epifactor	ROCK1	DR1	0.821726869	4.36E-31
UCS	Epifactor	ROCK1	SIRT1	0.822523722	3.42E-31
UCS	Epifactor	ROCK1	ZMYM2	0.823765009	2.33E-31
UCS	Epifactor	ROCK1	EP300	0.82550844	1.36E-31
UCS	Epifactor	ROCK1	NSD1	0.825935019	1.19E-31
UCS	Epifactor	ROCK1	EPC1	0.829271044	4.13E-32
UCS	Epifactor	ROCK1	PHC3	0.830422782	2.86E-32
UCS	Epifactor	ROCK1	HMG20A	0.830820033	2.51E-32
UCS	Epifactor	ROCK1	STK4	0.833379167	1.09E-32
UCS	Epifactor	ROCK1	EPC2	0.834509245	7.52E-33
UCS	Epifactor	ROCK1	SMEK2	0.834646842	7.18E-33
UCS	Epifactor	ROCK1	BRD3	0.836149263	4.36E-33
UCS	Epifactor	ROCK1	CDK17	0.836564946	3.79E-33
UCS	Epifactor	ROCK1	PPP4R2	0.836777391	3.53E-33
UCS	Epifactor	ROCK1	SHPRH	0.836980417	3.30E-33
UCS	Epifactor	ROCK1	CREBBP	0.838146272	2.22E-33
UCS	Epifactor	ROCK1	CTR9	0.838148187	2.22E-33
UCS	Epifactor	ROCK1	ATRX	0.84023532	1.09E-33
UCS	Epifactor	ROCK1	NCOR1	0.842890968	4.33E-34
UCS	Epifactor	ROCK1	PBRM1	0.843169668	3.92E-34
UCS	Epifactor	ROCK1	WAC	0.84485302	2.17E-34
UCS	Epifactor	ROCK1	BAZ2A	0.845676749	1.61E-34
UCS	Epifactor	ROCK1	USP49	0.846548087	1.18E-34
UCS	Epifactor	ROCK1	MBD5	0.846549065	1.18E-34
UCS	Epifactor	ROCK1	BRPF3	0.846771998	1.09E-34
UCS	Epifactor	ROCK1	KDM3A	0.84866636	5.48E-35
UCS	Epifactor	ROCK1	SETD2	0.853241238	1.00E-35
UCS	Epifactor	ROCK1	SMARCAD1	0.857171897	2.22E-36
UCS	Epifactor	ROCK1	MGA	0.857254605	2.15E-36
UCS	Epifactor	ROCK1	RSF1	0.857892247	1.68E-36
UCS	Epifactor	ROCK1	UBR5	0.859713578	8.19E-37
UCS	Epifactor	ROCK1	BARD1	0.860986432	4.93E-37
UCS	Epifactor	ROCK1	REST	0.86365758	1.67E-37
UCS	Epifactor	ROCK1	MAP3K7	0.867217724	3.82E-38
UCS	Epifactor	ROCK1	UBR2	0.868043538	2.70E-38
UCS	Epifactor	ROCK1	ATAD2B	0.87150114	6.10E-39
UCS	Epifactor	ROCK1	ATF2	0.874903646	1.35E-39
UCS	Epifactor	ROCK1	SMARCA5	0.886624247	5.31E-42
UCS	Epifactor	ROCK1	ARID4A	0.894938484	7.10E-44
UCS	Epifactor	ROCK1	NIPBL	0.896521791	3.00E-44
UCS	Epifactor	ROCK1	SF3B1	0.902259303	1.16E-45
UCS	Epifactor	ROCK1	TRRAP	0.904723648	2.71E-46
UCS	Epifactor	ROCK1	ARID1A	0.905191786	2.05E-46
UCS	Epifactor	ROCK1	BPTF	0.90914982	1.79E-47
UCS	Epifactor	ROCK1	C11orf30	0.931277789	1.85E-54
UCS	IUPHAR	ROCK1	SETD1B	0.801237936	1.55E-28
UCS	IUPHAR	ROCK1	SLC10A7	0.80207345	1.24E-28
UCS	IUPHAR	ROCK1	WNK1	0.802975393	9.67E-29
UCS	IUPHAR	ROCK1	SLC25A40	0.803792057	7.74E-29
UCS	IUPHAR	ROCK1	IL17RA	0.804868754	5.76E-29
UCS	IUPHAR	ROCK1	BRWD1	0.807067416	3.13E-29
UCS	IUPHAR	ROCK1	TPP2	0.807140424	3.07E-29
UCS	IUPHAR	ROCK1	PHF8	0.808956818	1.84E-29
UCS	IUPHAR	ROCK1	NEK1	0.809142264	1.75E-29
UCS	IUPHAR	ROCK1	ACER2	0.809311779	1.67E-29
UCS	IUPHAR	ROCK1	BIRC2	0.809475371	1.59E-29
UCS	IUPHAR	ROCK1	DYRK1A	0.809813856	1.45E-29
UCS	IUPHAR	ROCK1	GLS	0.810094856	1.33E-29
UCS	IUPHAR	ROCK1	PHF2	0.810901847	1.06E-29
UCS	IUPHAR	ROCK1	LATS1	0.811067006	1.01E-29
UCS	IUPHAR	ROCK1	NCOA1	0.811546725	8.82E-30
UCS	IUPHAR	ROCK1	SLC4A7	0.812550258	6.61E-30
UCS	IUPHAR	ROCK1	SENP1	0.817196465	1.70E-30
UCS	IUPHAR	ROCK1	SENP7	0.817593099	1.51E-30
UCS	IUPHAR	ROCK1	ERN1	0.818108894	1.30E-30
UCS	IUPHAR	ROCK1	TRIM33	0.821155116	5.18E-31
UCS	IUPHAR	ROCK1	SIRT1	0.822523722	3.42E-31
UCS	IUPHAR	ROCK1	SLC30A7	0.822658002	3.28E-31
UCS	IUPHAR	ROCK1	PPM1D	0.824104258	2.10E-31
UCS	IUPHAR	ROCK1	EP300	0.82550844	1.36E-31
UCS	IUPHAR	ROCK1	NSD1	0.825935019	1.19E-31
UCS	IUPHAR	ROCK1	STK4	0.833379167	1.09E-32
UCS	IUPHAR	ROCK1	NR2C2	0.833773356	9.59E-33
UCS	IUPHAR	ROCK1	BRD3	0.836149263	4.36E-33
UCS	IUPHAR	ROCK1	CDK17	0.836564946	3.79E-33
UCS	IUPHAR	ROCK1	CREBBP	0.838146272	2.22E-33
UCS	IUPHAR	ROCK1	SYNJ2	0.839511604	1.40E-33
UCS	IUPHAR	ROCK1	PIKFYVE	0.842339151	5.25E-34
UCS	IUPHAR	ROCK1	PBRM1	0.843169668	3.92E-34
UCS	IUPHAR	ROCK1	BAZ2A	0.845676749	1.61E-34
UCS	IUPHAR	ROCK1	DPP8	0.846538903	1.19E-34
UCS	IUPHAR	ROCK1	BRPF3	0.846771998	1.09E-34
UCS	IUPHAR	ROCK1	PIK3CA	0.847852081	7.37E-35
UCS	IUPHAR	ROCK1	KDM3A	0.84866636	5.48E-35
UCS	IUPHAR	ROCK1	SETD2	0.853241238	1.00E-35
UCS	IUPHAR	ROCK1	SLC35A3	0.860148847	6.89E-37
UCS	IUPHAR	ROCK1	SLC25A46	0.866104987	6.09E-38
UCS	IUPHAR	ROCK1	MAP3K7	0.867217724	3.82E-38
UCS	IUPHAR	ROCK1	SCYL2	0.871209578	6.93E-39
UCS	IUPHAR	ROCK1	TNKS2	0.871428756	6.30E-39
UCS	IUPHAR	ROCK1	ATAD2B	0.87150114	6.10E-39
UCS	IUPHAR	ROCK1	SLC12A6	0.881840569	5.47E-41
UCS	IUPHAR	ROCK1	BIRC6	0.897220596	2.04E-44
UCS	IUPHAR	ROCK1	HIPK1	0.900638461	2.97E-45
UCS	IUPHAR	ROCK1	ADAM10	0.904283192	3.53E-46
UCS	IUPHAR	ROCK1	TRRAP	0.904723648	2.71E-46
UCS	IUPHAR	ROCK1	BPTF	0.90914982	1.79E-47
UCS	IUPHAR	ROCK1	SMG1	0.910889672	5.90E-48
UCS	IUPHAR	ROCK1	PRPF4B	0.918614435	3.23E-50
UCS	Kinase	ROCK1	WNK1	0.802975393	9.67E-29
UCS	Kinase	ROCK1	NEK1	0.809142264	1.75E-29
UCS	Kinase	ROCK1	DYRK1A	0.809813856	1.45E-29
UCS	Kinase	ROCK1	LATS1	0.811067006	1.01E-29
UCS	Kinase	ROCK1	ERN1	0.818108894	1.30E-30
UCS	Kinase	ROCK1	TRIM33	0.821155116	5.18E-31
UCS	Kinase	ROCK1	STK4	0.833379167	1.09E-32
UCS	Kinase	ROCK1	BRD3	0.836149263	4.36E-33
UCS	Kinase	ROCK1	CDK17	0.836564946	3.79E-33
UCS	Kinase	ROCK1	MAP3K7	0.867217724	3.82E-38
UCS	Kinase	ROCK1	SCYL2	0.871209578	6.93E-39
UCS	Kinase	ROCK1	HIPK1	0.900638461	2.97E-45
UCS	Kinase	ROCK1	TRRAP	0.904723648	2.71E-46
UCS	Kinase	ROCK1	SMG1	0.910889672	5.90E-48
UCS	Kinase	ROCK1	PRPF4B	0.918614435	3.23E-50
UCS	TF	ROCK1	ZNF417	0.800185825	2.06E-28
UCS	TF	ROCK1	ZNF254	0.800751686	1.77E-28
UCS	TF	ROCK1	HIVEP2	0.800810034	1.74E-28
UCS	TF	ROCK1	SPEN	0.800965066	1.67E-28
UCS	TF	ROCK1	ZNF445	0.801807384	1.33E-28
UCS	TF	ROCK1	TET3	0.804442219	6.47E-29
UCS	TF	ROCK1	ZNF654	0.805414523	4.95E-29
UCS	TF	ROCK1	JRKL	0.810198742	1.30E-29
UCS	TF	ROCK1	ZSCAN12	0.810991338	1.03E-29
UCS	TF	ROCK1	NCOA1	0.811546725	8.82E-30
UCS	TF	ROCK1	KLF12	0.811985673	7.78E-30
UCS	TF	ROCK1	IKZF3	0.812413036	6.88E-30
UCS	TF	ROCK1	ZNF236	0.813082587	5.67E-30
UCS	TF	ROCK1	RFX3	0.814608697	3.64E-30
UCS	TF	ROCK1	ZNF234	0.815056807	3.19E-30
UCS	TF	ROCK1	ZNF510	0.815646269	2.69E-30
UCS	TF	ROCK1	ZBTB10	0.818959366	1.01E-30
UCS	TF	ROCK1	ZBTB44	0.821436831	4.76E-31
UCS	TF	ROCK1	TMF1	0.821539721	4.61E-31
UCS	TF	ROCK1	DR1	0.821726869	4.36E-31
UCS	TF	ROCK1	ZNF570	0.824403689	1.91E-31
UCS	TF	ROCK1	KLF7	0.828029484	6.14E-32
UCS	TF	ROCK1	ZNF148	0.829056447	4.43E-32
UCS	TF	ROCK1	HMG20A	0.830820033	2.51E-32
UCS	TF	ROCK1	ZNF281	0.830940572	2.42E-32
UCS	TF	ROCK1	FOXJ3	0.832090125	1.66E-32
UCS	TF	ROCK1	NR2C2	0.833773356	9.59E-33
UCS	TF	ROCK1	ZNF675	0.833954182	9.03E-33
UCS	TF	ROCK1	SP2	0.836394473	4.01E-33
UCS	TF	ROCK1	CREBZF	0.839520207	1.39E-33
UCS	TF	ROCK1	ZNF225	0.8418809	6.16E-34
UCS	TF	ROCK1	ZNF776	0.84215692	5.59E-34
UCS	TF	ROCK1	ZNF430	0.845046702	2.02E-34
UCS	TF	ROCK1	BAZ2A	0.845676749	1.61E-34
UCS	TF	ROCK1	ZFX	0.848526224	5.77E-35
UCS	TF	ROCK1	ZBTB39	0.849344443	4.28E-35
UCS	TF	ROCK1	ZNF518A	0.851568967	1.88E-35
UCS	TF	ROCK1	ZNF765	0.853673616	8.52E-36
UCS	TF	ROCK1	ZNF813	0.855197265	4.77E-36
UCS	TF	ROCK1	ZBTB34	0.857183566	2.21E-36
UCS	TF	ROCK1	MGA	0.857254605	2.15E-36
UCS	TF	ROCK1	ZNF397	0.861576952	3.89E-37
UCS	TF	ROCK1	ZNF611	0.862577228	2.60E-37
UCS	TF	ROCK1	ZNF407	0.86349003	1.79E-37
UCS	TF	ROCK1	REST	0.86365758	1.67E-37
UCS	TF	ROCK1	ZNF701	0.864502226	1.18E-37
UCS	TF	ROCK1	ZNF431	0.865808105	6.89E-38
UCS	TF	ROCK1	ELF1	0.87396264	2.06E-39
UCS	TF	ROCK1	ATF2	0.874903646	1.35E-39
UCS	TF	ROCK1	FOXN2	0.875170895	1.20E-39
UCS	TF	ROCK1	ATF1	0.876055724	8.06E-40
UCS	TF	ROCK1	SON	0.877910896	3.45E-40
UCS	TF	ROCK1	ZBTB11	0.882469127	4.05E-41
UCS	TF	ROCK1	ZNF800	0.886910635	4.60E-42
UCS	TF	ROCK1	SP3	0.888465306	2.10E-42
UCS	TF	ROCK1	ZNF644	0.891236542	5.06E-43
UCS	TF	ROCK1	RLF	0.891935417	3.51E-43
UCS	TF	ROCK1	ZFP91	0.901053778	2.34E-45
UCS	TF	ROCK1	BPTF	0.90914982	1.79E-47
UCS	TF	ROCK1	ZNF292	0.910577469	7.21E-48
UCS	TF	ROCK1	SP4	0.914407314	5.86E-49
UCS	TF	ROCK1	ZNF318	0.919961818	1.24E-50
UCS	TF	ROCK1	CREB1	0.934349516	1.31E-55
UCS	TSG	ROCK1	VHL	0.807057837	3.14E-29
UCS	TSG	ROCK1	WHSC1L1	0.807680404	2.64E-29
UCS	TSG	ROCK1	USP33	0.808883032	1.88E-29
UCS	TSG	ROCK1	TP53BP1	0.809893729	1.41E-29
UCS	TSG	ROCK1	PDS5B	0.810340254	1.24E-29
UCS	TSG	ROCK1	LATS1	0.811067006	1.01E-29
UCS	TSG	ROCK1	ANAPC1	0.812089479	7.55E-30
UCS	TSG	ROCK1	IKZF3	0.812413036	6.88E-30
UCS	TSG	ROCK1	IGF2R	0.814967791	3.28E-30
UCS	TSG	ROCK1	SIRT1	0.822523722	3.42E-31
UCS	TSG	ROCK1	RB1CC1	0.827881079	6.43E-32
UCS	TSG	ROCK1	PHC3	0.830422782	2.86E-32
UCS	TSG	ROCK1	NR2C2	0.833773356	9.59E-33
UCS	TSG	ROCK1	SHPRH	0.836980417	3.30E-33
UCS	TSG	ROCK1	CREBBP	0.838146272	2.22E-33
UCS	TSG	ROCK1	DIDO1	0.838669209	1.86E-33
UCS	TSG	ROCK1	CBL	0.840047916	1.16E-33
UCS	TSG	ROCK1	PBRM1	0.843169668	3.92E-34
UCS	TSG	ROCK1	RBL1	0.844139197	2.79E-34
UCS	TSG	ROCK1	KDM3A	0.84866636	5.48E-35
UCS	TSG	ROCK1	RBL2	0.848699838	5.42E-35
UCS	TSG	ROCK1	SETD2	0.853241238	1.00E-35
UCS	TSG	ROCK1	PTPN11	0.860171194	6.83E-37
UCS	TSG	ROCK1	BARD1	0.860986432	4.93E-37
UCS	TSG	ROCK1	HACE1	0.872774987	3.49E-39
UCS	TSG	ROCK1	SMCHD1	0.900166219	3.89E-45
UCS	TSG	ROCK1	ARID1A	0.905191786	2.05E-46
UCS	TSG	ROCK1	ZNF292	0.910577469	7.21E-48
UVM	Cell metabolism gene	ROCK1	POLD3	0.801579064	4.21E-19
UVM	Cell metabolism gene	ROCK1	PPP1CB	0.801903805	3.97E-19
UVM	Cell metabolism gene	ROCK1	FPGT	0.80371463	2.88E-19
UVM	Cell metabolism gene	ROCK1	GNPDA2	0.807070829	1.57E-19
UVM	Cell metabolism gene	ROCK1	RORA	0.808725887	1.16E-19
UVM	Cell metabolism gene	ROCK1	NUP54	0.808987119	1.11E-19
UVM	Cell metabolism gene	ROCK1	HMGCS1	0.809647429	9.83E-20
UVM	Cell metabolism gene	ROCK1	NUPL2	0.810148575	8.96E-20
UVM	Cell metabolism gene	ROCK1	POLR2B	0.810685734	8.11E-20
UVM	Cell metabolism gene	ROCK1	NUP107	0.81246082	5.82E-20
UVM	Cell metabolism gene	ROCK1	PIK3C2A	0.812537279	5.74E-20
UVM	Cell metabolism gene	ROCK1	AGPS	0.813505604	4.78E-20
UVM	Cell metabolism gene	ROCK1	TRMT11	0.813516898	4.77E-20
UVM	Cell metabolism gene	ROCK1	CDK8	0.815200971	3.47E-20
UVM	Cell metabolism gene	ROCK1	TNPO1	0.818225124	1.94E-20
UVM	Cell metabolism gene	ROCK1	PI4K2B	0.818500818	1.84E-20
UVM	Cell metabolism gene	ROCK1	IDI1	0.819606366	1.48E-20
UVM	Cell metabolism gene	ROCK1	GLS	0.822361644	8.58E-21
UVM	Cell metabolism gene	ROCK1	SACM1L	0.823202684	7.25E-21
UVM	Cell metabolism gene	ROCK1	AGL	0.823930644	6.27E-21
UVM	Cell metabolism gene	ROCK1	PANK3	0.824475341	5.62E-21
UVM	Cell metabolism gene	ROCK1	PLA2G12A	0.827247712	3.19E-21
UVM	Cell metabolism gene	ROCK1	PSMC6	0.828193219	2.63E-21
UVM	Cell metabolism gene	ROCK1	GPAM	0.828768804	2.33E-21
UVM	Cell metabolism gene	ROCK1	HIF1A	0.828883121	2.28E-21
UVM	Cell metabolism gene	ROCK1	SEC24B	0.829710087	1.92E-21
UVM	Cell metabolism gene	ROCK1	DBT	0.831468362	1.32E-21
UVM	Cell metabolism gene	ROCK1	ALG13	0.832821736	9.94E-22
UVM	Cell metabolism gene	ROCK1	NUDT12	0.83283013	9.92E-22
UVM	Cell metabolism gene	ROCK1	PIGA	0.83392885	7.84E-22
UVM	Cell metabolism gene	ROCK1	IPMK	0.834410905	7.07E-22
UVM	Cell metabolism gene	ROCK1	PPAT	0.836376683	4.62E-22
UVM	Cell metabolism gene	ROCK1	PHAX	0.836434219	4.56E-22
UVM	Cell metabolism gene	ROCK1	GPD2	0.836766875	4.24E-22
UVM	Cell metabolism gene	ROCK1	UPF2	0.839049245	2.56E-22
UVM	Cell metabolism gene	ROCK1	TRDMT1	0.841189057	1.59E-22
UVM	Cell metabolism gene	ROCK1	NUP50	0.84180719	1.38E-22
UVM	Cell metabolism gene	ROCK1	L2HGDH	0.842876308	1.08E-22
UVM	Cell metabolism gene	ROCK1	NAMPT	0.843883895	8.59E-23
UVM	Cell metabolism gene	ROCK1	AASDHPPT	0.844516222	7.43E-23
UVM	Cell metabolism gene	ROCK1	MAN1A2	0.845477467	5.95E-23
UVM	Cell metabolism gene	ROCK1	MANEA	0.849261625	2.44E-23
UVM	Cell metabolism gene	ROCK1	PIK3R1	0.851359973	1.47E-23
UVM	Cell metabolism gene	ROCK1	UGGT2	0.85442615	6.94E-24
UVM	Cell metabolism gene	ROCK1	XPO1	0.854433523	6.93E-24
UVM	Cell metabolism gene	ROCK1	ACSL4	0.857035201	3.61E-24
UVM	Cell metabolism gene	ROCK1	DCK	0.861582434	1.12E-24
UVM	Cell metabolism gene	ROCK1	SUCLA2	0.862199195	9.53E-25
UVM	Cell metabolism gene	ROCK1	PIK3C3	0.862460795	8.89E-25
UVM	Cell metabolism gene	ROCK1	ACADSB	0.864100801	5.75E-25
UVM	Cell metabolism gene	ROCK1	EDEM3	0.867215097	2.48E-25
UVM	Cell metabolism gene	ROCK1	MED17	0.868135125	1.92E-25
UVM	Cell metabolism gene	ROCK1	ALG10B	0.868464154	1.76E-25
UVM	Cell metabolism gene	ROCK1	COL4A3BP	0.868766289	1.62E-25
UVM	Cell metabolism gene	ROCK1	DIS3	0.868864373	1.57E-25
UVM	Cell metabolism gene	ROCK1	PIK3CA	0.872043533	6.43E-26
UVM	Cell metabolism gene	ROCK1	ETNK1	0.877289121	1.39E-26
UVM	Cell metabolism gene	ROCK1	PRKAA1	0.877897767	1.16E-26
UVM	Cell metabolism gene	ROCK1	GXYLT1	0.878701314	9.12E-27
UVM	Cell metabolism gene	ROCK1	CSGALNACT2	0.879155677	7.95E-27
UVM	Cell metabolism gene	ROCK1	PNPLA8	0.880127349	5.91E-27
UVM	Cell metabolism gene	ROCK1	NUPL1	0.880685736	4.98E-27
UVM	Cell metabolism gene	ROCK1	FAR1	0.883665029	1.97E-27
UVM	Cell metabolism gene	ROCK1	CLOCK	0.887177761	6.38E-28
UVM	Cell metabolism gene	ROCK1	MTMR6	0.888880096	3.65E-28
UVM	Cell metabolism gene	ROCK1	MTR	0.896949284	2.26E-29
UVM	Cell metabolism gene	ROCK1	FBXL3	0.898250857	1.41E-29
UVM	Cell metabolism gene	ROCK1	PIKFYVE	0.904249956	1.48E-30
UVM	Cell metabolism gene	ROCK1	SMG1	0.930012544	1.20E-35
UVM	Cell metabolism gene	ROCK1	RANBP2	0.940652804	2.36E-38
UVM	CGC	ROCK1	FIP1L1	0.803428646	3.03E-19
UVM	CGC	ROCK1	GOLGA5	0.804503992	2.50E-19
UVM	CGC	ROCK1	MAP3K1	0.805370223	2.14E-19
UVM	CGC	ROCK1	NFE2L2	0.806399927	1.78E-19
UVM	CGC	ROCK1	CDKN1B	0.807048421	1.58E-19
UVM	CGC	ROCK1	BRIP1	0.807356619	1.50E-19
UVM	CGC	ROCK1	TRIM24	0.812925231	5.33E-20
UVM	CGC	ROCK1	STRN	0.818235632	1.93E-20
UVM	CGC	ROCK1	RAD17	0.818612598	1.80E-20
UVM	CGC	ROCK1	ABI1	0.820327719	1.28E-20
UVM	CGC	ROCK1	BMPR1A	0.826023235	4.10E-21
UVM	CGC	ROCK1	HIF1A	0.828883121	2.28E-21
UVM	CGC	ROCK1	TET2	0.830106105	1.76E-21
UVM	CGC	ROCK1	STAG1	0.830975142	1.47E-21
UVM	CGC	ROCK1	TRIM33	0.834609773	6.77E-22
UVM	CGC	ROCK1	GOPC	0.837551999	3.57E-22
UVM	CGC	ROCK1	PTPN11	0.838779985	2.72E-22
UVM	CGC	ROCK1	RB1	0.839862412	2.14E-22
UVM	CGC	ROCK1	MSH2	0.840747906	1.75E-22
UVM	CGC	ROCK1	ARHGAP5	0.841477604	1.49E-22
UVM	CGC	ROCK1	BAZ1A	0.842170448	1.27E-22
UVM	CGC	ROCK1	JAK2	0.842579892	1.16E-22
UVM	CGC	ROCK1	PWWP2A	0.848153029	3.17E-23
UVM	CGC	ROCK1	KDM5A	0.849728346	2.18E-23
UVM	CGC	ROCK1	SMAD4	0.850085485	2.00E-23
UVM	CGC	ROCK1	HSP90AA1	0.850282081	1.91E-23
UVM	CGC	ROCK1	ZMYM2	0.850612228	1.76E-23
UVM	CGC	ROCK1	PIK3R1	0.851359973	1.47E-23
UVM	CGC	ROCK1	DDX5	0.85228328	1.18E-23
UVM	CGC	ROCK1	DDX10	0.852944801	1.00E-23
UVM	CGC	ROCK1	XPO1	0.854433523	6.93E-24
UVM	CGC	ROCK1	ATF1	0.854544072	6.74E-24
UVM	CGC	ROCK1	ERCC4	0.855200954	5.72E-24
UVM	CGC	ROCK1	ARID2	0.855339533	5.53E-24
UVM	CGC	ROCK1	AFF4	0.856573795	4.06E-24
UVM	CGC	ROCK1	DEK	0.857835778	2.95E-24
UVM	CGC	ROCK1	ATM	0.857906834	2.89E-24
UVM	CGC	ROCK1	TOP1	0.860775129	1.38E-24
UVM	CGC	ROCK1	BRCA2	0.860841934	1.36E-24
UVM	CGC	ROCK1	CLIP1	0.861640546	1.10E-24
UVM	CGC	ROCK1	IL6ST	0.861880485	1.04E-24
UVM	CGC	ROCK1	PMS1	0.866968948	2.65E-25
UVM	CGC	ROCK1	KRAS	0.867216849	2.48E-25
UVM	CGC	ROCK1	BIRC6	0.869771828	1.22E-25
UVM	CGC	ROCK1	ITGAV	0.870401084	1.02E-25
UVM	CGC	ROCK1	PIK3CA	0.872043533	6.43E-26
UVM	CGC	ROCK1	MLLT10	0.873044618	4.83E-26
UVM	CGC	ROCK1	FBXO11	0.874480388	3.19E-26
UVM	CGC	ROCK1	ETNK1	0.877289121	1.39E-26
UVM	CGC	ROCK1	MALT1	0.879818252	6.50E-27
UVM	CGC	ROCK1	CREB1	0.88241869	2.91E-27
UVM	CGC	ROCK1	PHF6	0.883233104	2.26E-27
UVM	CGC	ROCK1	CUL3	0.883409853	2.14E-27
UVM	CGC	ROCK1	CDC73	0.887716388	5.35E-28
UVM	CGC	ROCK1	STAG2	0.888008731	4.86E-28
UVM	CGC	ROCK1	AKAP9	0.889046985	3.45E-28
UVM	CGC	ROCK1	BCLAF1	0.890040715	2.48E-28
UVM	CGC	ROCK1	APC	0.890110244	2.42E-28
UVM	CGC	ROCK1	N4BP2	0.892685951	1.01E-28
UVM	CGC	ROCK1	DICER1	0.898400162	1.34E-29
UVM	CGC	ROCK1	SF3B1	0.898995886	1.07E-29
UVM	CGC	ROCK1	TRIP11	0.901897773	3.65E-30
UVM	CGC	ROCK1	RGPD3	0.907805473	3.63E-31
UVM	CGC	ROCK1	USP8	0.915515028	1.40E-32
UVM	CGC	ROCK1	SUZ12	0.915581045	1.36E-32
UVM	CGC	ROCK1	ATRX	0.923767401	2.97E-34
UVM	CGC	ROCK1	KTN1	0.927508079	4.49E-35
UVM	CGC	ROCK1	KIF5B	0.932142773	3.73E-36
UVM	CGC	ROCK1	RANBP2	0.940652804	2.36E-38
UVM	Epifactor	ROCK1	ANKRD32	0.802268488	3.73E-19
UVM	Epifactor	ROCK1	HMGN5	0.80334134	3.08E-19
UVM	Epifactor	ROCK1	TAF7	0.809975212	9.25E-20
UVM	Epifactor	ROCK1	PHF20L1	0.810210075	8.86E-20
UVM	Epifactor	ROCK1	DNAJC2	0.810384739	8.57E-20
UVM	Epifactor	ROCK1	YY1	0.812098067	6.23E-20
UVM	Epifactor	ROCK1	TRIM24	0.812925231	5.33E-20
UVM	Epifactor	ROCK1	SUV420H1	0.812963276	5.30E-20
UVM	Epifactor	ROCK1	MAP3K7	0.813932485	4.41E-20
UVM	Epifactor	ROCK1	MASTL	0.814866724	3.69E-20
UVM	Epifactor	ROCK1	PPP4R2	0.815500206	3.27E-20
UVM	Epifactor	ROCK1	SENP1	0.815811909	3.08E-20
UVM	Epifactor	ROCK1	CIR1	0.816545498	2.68E-20
UVM	Epifactor	ROCK1	TDG	0.816599676	2.65E-20
UVM	Epifactor	ROCK1	CUL4B	0.817680327	2.15E-20
UVM	Epifactor	ROCK1	ASH1L	0.818889329	1.70E-20
UVM	Epifactor	ROCK1	INO80D	0.820108738	1.34E-20
UVM	Epifactor	ROCK1	C11orf30	0.821098954	1.10E-20
UVM	Epifactor	ROCK1	BRWD1	0.823572268	6.74E-21
UVM	Epifactor	ROCK1	SIRT1	0.826052438	4.08E-21
UVM	Epifactor	ROCK1	MGA	0.826950902	3.39E-21
UVM	Epifactor	ROCK1	LEO1	0.827131743	3.27E-21
UVM	Epifactor	ROCK1	INO80	0.828354905	2.54E-21
UVM	Epifactor	ROCK1	TET2	0.830106105	1.76E-21
UVM	Epifactor	ROCK1	RCOR3	0.830140286	1.75E-21
UVM	Epifactor	ROCK1	MBTD1	0.832202771	1.13E-21
UVM	Epifactor	ROCK1	SUDS3	0.832785044	1.00E-21
UVM	Epifactor	ROCK1	TRIM33	0.834609773	6.77E-22
UVM	Epifactor	ROCK1	CHUK	0.835551165	5.52E-22
UVM	Epifactor	ROCK1	PARG	0.836951751	4.07E-22
UVM	Epifactor	ROCK1	CTBP2	0.837289221	3.78E-22
UVM	Epifactor	ROCK1	RB1	0.839862412	2.14E-22
UVM	Epifactor	ROCK1	HAT1	0.840336665	1.92E-22
UVM	Epifactor	ROCK1	DDX21	0.840665607	1.79E-22
UVM	Epifactor	ROCK1	WAC	0.841786432	1.39E-22
UVM	Epifactor	ROCK1	BAZ1A	0.842170448	1.27E-22
UVM	Epifactor	ROCK1	JAK2	0.842579892	1.16E-22
UVM	Epifactor	ROCK1	CDK17	0.842984287	1.06E-22
UVM	Epifactor	ROCK1	USP12	0.843541455	9.30E-23
UVM	Epifactor	ROCK1	BRMS1L	0.84450064	7.45E-23
UVM	Epifactor	ROCK1	HCFC2	0.844910731	6.78E-23
UVM	Epifactor	ROCK1	BPTF	0.845928622	5.35E-23
UVM	Epifactor	ROCK1	TAF1	0.84661752	4.56E-23
UVM	Epifactor	ROCK1	AEBP2	0.849514385	2.30E-23
UVM	Epifactor	ROCK1	KDM5A	0.849728346	2.18E-23
UVM	Epifactor	ROCK1	ZMYM2	0.850612228	1.76E-23
UVM	Epifactor	ROCK1	FAM175B	0.852383783	1.15E-23
UVM	Epifactor	ROCK1	YEATS4	0.853280154	9.21E-24
UVM	Epifactor	ROCK1	SHPRH	0.853297521	9.17E-24
UVM	Epifactor	ROCK1	ARID2	0.855339533	5.53E-24
UVM	Epifactor	ROCK1	UHRF2	0.855366699	5.49E-24
UVM	Epifactor	ROCK1	SMARCA5	0.857651211	3.09E-24
UVM	Epifactor	ROCK1	DEK	0.857835778	2.95E-24
UVM	Epifactor	ROCK1	ATM	0.857906834	2.89E-24
UVM	Epifactor	ROCK1	PHIP	0.858095013	2.76E-24
UVM	Epifactor	ROCK1	RLIM	0.859096495	2.13E-24
UVM	Epifactor	ROCK1	BRCA2	0.860841934	1.36E-24
UVM	Epifactor	ROCK1	DNTTIP2	0.861604125	1.11E-24
UVM	Epifactor	ROCK1	SMARCAD1	0.86213985	9.68E-25
UVM	Epifactor	ROCK1	MYSM1	0.863223497	7.27E-25
UVM	Epifactor	ROCK1	RMI1	0.863993812	5.92E-25
UVM	Epifactor	ROCK1	ZRANB3	0.864466124	5.22E-25
UVM	Epifactor	ROCK1	ATF2	0.866483558	3.03E-25
UVM	Epifactor	ROCK1	EPC1	0.866811754	2.77E-25
UVM	Epifactor	ROCK1	MLLT10	0.873044618	4.83E-26
UVM	Epifactor	ROCK1	ZMYND11	0.875099705	2.66E-26
UVM	Epifactor	ROCK1	ATAD2B	0.875189305	2.59E-26
UVM	Epifactor	ROCK1	OGT	0.875323506	2.49E-26
UVM	Epifactor	ROCK1	PRKAA1	0.877897767	1.16E-26
UVM	Epifactor	ROCK1	CHD1	0.880914695	4.64E-27
UVM	Epifactor	ROCK1	CUL3	0.883409853	2.14E-27
UVM	Epifactor	ROCK1	PHF14	0.883728469	1.93E-27
UVM	Epifactor	ROCK1	TLK1	0.885523388	1.09E-27
UVM	Epifactor	ROCK1	USP15	0.885532976	1.09E-27
UVM	Epifactor	ROCK1	CLOCK	0.887177761	6.38E-28
UVM	Epifactor	ROCK1	CDC73	0.887716388	5.35E-28
UVM	Epifactor	ROCK1	UCHL5	0.889262262	3.21E-28
UVM	Epifactor	ROCK1	SMEK1	0.890749449	1.95E-28
UVM	Epifactor	ROCK1	ARID4B	0.893008608	9.03E-29
UVM	Epifactor	ROCK1	REST	0.896878382	2.32E-29
UVM	Epifactor	ROCK1	SF3B1	0.898995886	1.07E-29
UVM	Epifactor	ROCK1	BAZ2B	0.899450483	9.09E-30
UVM	Epifactor	ROCK1	SMEK2	0.901375972	4.44E-30
UVM	Epifactor	ROCK1	BRCC3	0.902096372	3.38E-30
UVM	Epifactor	ROCK1	CHD9	0.902398784	3.02E-30
UVM	Epifactor	ROCK1	ARID4A	0.908600626	2.63E-31
UVM	Epifactor	ROCK1	BRWD3	0.90952445	1.80E-31
UVM	Epifactor	ROCK1	CUL2	0.910297249	1.31E-31
UVM	Epifactor	ROCK1	SUZ12	0.915581045	1.36E-32
UVM	Epifactor	ROCK1	MPHOSPH8	0.9184476	3.73E-33
UVM	Epifactor	ROCK1	JMJD1C	0.923102787	4.12E-34
UVM	Epifactor	ROCK1	ATRX	0.923767401	2.97E-34
UVM	Epifactor	ROCK1	EPC2	0.924624672	1.95E-34
UVM	Epifactor	ROCK1	CUL5	0.934391561	1.05E-36
UVM	Epifactor	ROCK1	RSF1	0.939964633	3.65E-38
UVM	Epifactor	ROCK1	NIPBL	0.946649076	4.15E-40
UVM	IUPHAR	ROCK1	SLC30A9	0.800180697	5.38E-19
UVM	IUPHAR	ROCK1	SLC12A2	0.801816578	4.03E-19
UVM	IUPHAR	ROCK1	CASK	0.802515719	3.57E-19
UVM	IUPHAR	ROCK1	PRMT3	0.804320672	2.59E-19
UVM	IUPHAR	ROCK1	SLC2A13	0.804834602	2.36E-19
UVM	IUPHAR	ROCK1	MAP3K1	0.805370223	2.14E-19
UVM	IUPHAR	ROCK1	CLK4	0.806104032	1.88E-19
UVM	IUPHAR	ROCK1	NFE2L2	0.806399927	1.78E-19
UVM	IUPHAR	ROCK1	STK17A	0.806636106	1.70E-19
UVM	IUPHAR	ROCK1	CDK13	0.808355457	1.25E-19
UVM	IUPHAR	ROCK1	MAGT1	0.808673395	1.18E-19
UVM	IUPHAR	ROCK1	SENP7	0.808705867	1.17E-19
UVM	IUPHAR	ROCK1	RORA	0.808725887	1.16E-19
UVM	IUPHAR	ROCK1	HMGCS1	0.809647429	9.83E-20
UVM	IUPHAR	ROCK1	ATP11B	0.810281211	8.74E-20
UVM	IUPHAR	ROCK1	ATP6V0A2	0.810444795	8.48E-20
UVM	IUPHAR	ROCK1	ATP7A	0.81141235	7.08E-20
UVM	IUPHAR	ROCK1	SLC4A7	0.811829992	6.55E-20
UVM	IUPHAR	ROCK1	NAPEPLD	0.812139058	6.18E-20
UVM	IUPHAR	ROCK1	PIK3C2A	0.812537279	5.74E-20
UVM	IUPHAR	ROCK1	TRIM24	0.812925231	5.33E-20
UVM	IUPHAR	ROCK1	MAP3K7	0.813932485	4.41E-20
UVM	IUPHAR	ROCK1	SLC35F5	0.81443463	4.01E-20
UVM	IUPHAR	ROCK1	MASTL	0.814866724	3.69E-20
UVM	IUPHAR	ROCK1	CDK8	0.815200971	3.47E-20
UVM	IUPHAR	ROCK1	SENP1	0.815811909	3.08E-20
UVM	IUPHAR	ROCK1	NR3C1	0.816233441	2.85E-20
UVM	IUPHAR	ROCK1	TAOK1	0.817090718	2.41E-20
UVM	IUPHAR	ROCK1	STK38L	0.81808441	1.99E-20
UVM	IUPHAR	ROCK1	LNPEP	0.818409358	1.87E-20
UVM	IUPHAR	ROCK1	PI4K2B	0.818500818	1.84E-20
UVM	IUPHAR	ROCK1	ASH1L	0.818889329	1.70E-20
UVM	IUPHAR	ROCK1	MAP4K3	0.819317239	1.57E-20
UVM	IUPHAR	ROCK1	IDI1	0.819606366	1.48E-20
UVM	IUPHAR	ROCK1	ATP2B1	0.822011001	9.20E-21
UVM	IUPHAR	ROCK1	GLS	0.822361644	8.58E-21
UVM	IUPHAR	ROCK1	BRWD1	0.823572268	6.74E-21
UVM	IUPHAR	ROCK1	DPP8	0.824071721	6.09E-21
UVM	IUPHAR	ROCK1	BMPR1A	0.826023235	4.10E-21
UVM	IUPHAR	ROCK1	SIRT1	0.826052438	4.08E-21
UVM	IUPHAR	ROCK1	MAPK6	0.826659526	3.60E-21
UVM	IUPHAR	ROCK1	PLA2G12A	0.827247712	3.19E-21
UVM	IUPHAR	ROCK1	NIPA1	0.827271321	3.18E-21
UVM	IUPHAR	ROCK1	YES1	0.828919938	2.26E-21
UVM	IUPHAR	ROCK1	ATP11C	0.829072132	2.19E-21
UVM	IUPHAR	ROCK1	IRAK4	0.833023893	9.52E-22
UVM	IUPHAR	ROCK1	TRIM33	0.834609773	6.77E-22
UVM	IUPHAR	ROCK1	NR2C1	0.834633103	6.74E-22
UVM	IUPHAR	ROCK1	CHUK	0.835551165	5.52E-22
UVM	IUPHAR	ROCK1	PPAT	0.836376683	4.62E-22
UVM	IUPHAR	ROCK1	ADAM17	0.836983745	4.04E-22
UVM	IUPHAR	ROCK1	SLC25A24	0.83736468	3.72E-22
UVM	IUPHAR	ROCK1	TBK1	0.838419286	2.95E-22
UVM	IUPHAR	ROCK1	HAT1	0.840336665	1.92E-22
UVM	IUPHAR	ROCK1	PKN2	0.841566761	1.46E-22
UVM	IUPHAR	ROCK1	BAZ1A	0.842170448	1.27E-22
UVM	IUPHAR	ROCK1	JAK2	0.842579892	1.16E-22
UVM	IUPHAR	ROCK1	CDK17	0.842984287	1.06E-22
UVM	IUPHAR	ROCK1	SLC30A5	0.843122163	1.02E-22
UVM	IUPHAR	ROCK1	SLC25A46	0.845460324	5.97E-23
UVM	IUPHAR	ROCK1	NEK7	0.845655932	5.70E-23
UVM	IUPHAR	ROCK1	BPTF	0.845928622	5.35E-23
UVM	IUPHAR	ROCK1	TAF1	0.84661752	4.56E-23
UVM	IUPHAR	ROCK1	BMP2K	0.847841388	3.42E-23
UVM	IUPHAR	ROCK1	VRK2	0.84964509	2.22E-23
UVM	IUPHAR	ROCK1	KDM5A	0.849728346	2.18E-23
UVM	IUPHAR	ROCK1	HSP90AA1	0.850282081	1.91E-23
UVM	IUPHAR	ROCK1	USP1	0.850654047	1.75E-23
UVM	IUPHAR	ROCK1	MFN1	0.851221801	1.52E-23
UVM	IUPHAR	ROCK1	PIK3R1	0.851359973	1.47E-23
UVM	IUPHAR	ROCK1	XPO1	0.854433523	6.93E-24
UVM	IUPHAR	ROCK1	ATM	0.857906834	2.89E-24
UVM	IUPHAR	ROCK1	PHIP	0.858095013	2.76E-24
UVM	IUPHAR	ROCK1	TOP1	0.860775129	1.38E-24
UVM	IUPHAR	ROCK1	CSNK1G3	0.861668352	1.10E-24
UVM	IUPHAR	ROCK1	IL6ST	0.861880485	1.04E-24
UVM	IUPHAR	ROCK1	PIK3C3	0.862460795	8.89E-25
UVM	IUPHAR	ROCK1	SENP6	0.863046944	7.61E-25
UVM	IUPHAR	ROCK1	BMPR2	0.863828877	6.19E-25
UVM	IUPHAR	ROCK1	HIPK3	0.864901544	4.64E-25
UVM	IUPHAR	ROCK1	KRAS	0.867216849	2.48E-25
UVM	IUPHAR	ROCK1	TTBK2	0.869690266	1.25E-25
UVM	IUPHAR	ROCK1	BIRC6	0.869771828	1.22E-25
UVM	IUPHAR	ROCK1	ITGAV	0.870401084	1.02E-25
UVM	IUPHAR	ROCK1	PIK3CA	0.872043533	6.43E-26
UVM	IUPHAR	ROCK1	BIRC2	0.873399661	4.36E-26
UVM	IUPHAR	ROCK1	FBXO11	0.874480388	3.19E-26
UVM	IUPHAR	ROCK1	ZMYND11	0.875099705	2.66E-26
UVM	IUPHAR	ROCK1	ATAD2B	0.875189305	2.59E-26
UVM	IUPHAR	ROCK1	PRKAA1	0.877897767	1.16E-26
UVM	IUPHAR	ROCK1	USP14	0.878247282	1.05E-26
UVM	IUPHAR	ROCK1	MALT1	0.879818252	6.50E-27
UVM	IUPHAR	ROCK1	TNKS2	0.884199043	1.66E-27
UVM	IUPHAR	ROCK1	TLK1	0.885523388	1.09E-27
UVM	IUPHAR	ROCK1	SCYL2	0.887114073	6.52E-28
UVM	IUPHAR	ROCK1	CLOCK	0.887177761	6.38E-28
UVM	IUPHAR	ROCK1	MTR	0.896949284	2.26E-29
UVM	IUPHAR	ROCK1	BAZ2B	0.899450483	9.09E-30
UVM	IUPHAR	ROCK1	TRPM7	0.901763105	3.84E-30
UVM	IUPHAR	ROCK1	PIKFYVE	0.904249956	1.48E-30
UVM	IUPHAR	ROCK1	XIAP	0.907450866	4.19E-31
UVM	IUPHAR	ROCK1	NEK1	0.907638345	3.88E-31
UVM	IUPHAR	ROCK1	BRWD3	0.90952445	1.80E-31
UVM	IUPHAR	ROCK1	PRPF4B	0.912896468	4.37E-32
UVM	IUPHAR	ROCK1	RIOK3	0.915343312	1.51E-32
UVM	IUPHAR	ROCK1	JMJD1C	0.923102787	4.12E-34
UVM	IUPHAR	ROCK1	MAP3K2	0.923230786	3.87E-34
UVM	IUPHAR	ROCK1	SMG1	0.930012544	1.20E-35
UVM	IUPHAR	ROCK1	SLK	0.954963365	6.57E-43
UVM	Kinase	ROCK1	CASK	0.802515719	3.57E-19
UVM	Kinase	ROCK1	MAP3K1	0.805370223	2.14E-19
UVM	Kinase	ROCK1	CLK4	0.806104032	1.88E-19
UVM	Kinase	ROCK1	STK17A	0.806636106	1.70E-19
UVM	Kinase	ROCK1	CDK13	0.808355457	1.25E-19
UVM	Kinase	ROCK1	TRIM24	0.812925231	5.33E-20
UVM	Kinase	ROCK1	MAP3K7	0.813932485	4.41E-20
UVM	Kinase	ROCK1	MASTL	0.814866724	3.69E-20
UVM	Kinase	ROCK1	CDK8	0.815200971	3.47E-20
UVM	Kinase	ROCK1	TAOK1	0.817090718	2.41E-20
UVM	Kinase	ROCK1	STK38L	0.81808441	1.99E-20
UVM	Kinase	ROCK1	MAP4K3	0.819317239	1.57E-20
UVM	Kinase	ROCK1	BMPR1A	0.826023235	4.10E-21
UVM	Kinase	ROCK1	MAPK6	0.826659526	3.60E-21
UVM	Kinase	ROCK1	YES1	0.828919938	2.26E-21
UVM	Kinase	ROCK1	IRAK4	0.833023893	9.52E-22
UVM	Kinase	ROCK1	TRIM33	0.834609773	6.77E-22
UVM	Kinase	ROCK1	CHUK	0.835551165	5.52E-22
UVM	Kinase	ROCK1	TBK1	0.838419286	2.95E-22
UVM	Kinase	ROCK1	PAN3	0.839429023	2.35E-22
UVM	Kinase	ROCK1	PKN2	0.841566761	1.46E-22
UVM	Kinase	ROCK1	BAZ1A	0.842170448	1.27E-22
UVM	Kinase	ROCK1	JAK2	0.842579892	1.16E-22
UVM	Kinase	ROCK1	CDK17	0.842984287	1.06E-22
UVM	Kinase	ROCK1	NEK7	0.845655932	5.70E-23
UVM	Kinase	ROCK1	TAF1	0.84661752	4.56E-23
UVM	Kinase	ROCK1	BMP2K	0.847841388	3.42E-23
UVM	Kinase	ROCK1	VRK2	0.84964509	2.22E-23
UVM	Kinase	ROCK1	ATM	0.857906834	2.89E-24
UVM	Kinase	ROCK1	CSNK1G3	0.861668352	1.10E-24
UVM	Kinase	ROCK1	BMPR2	0.863828877	6.19E-25
UVM	Kinase	ROCK1	HIPK3	0.864901544	4.64E-25
UVM	Kinase	ROCK1	COL4A3BP	0.868766289	1.62E-25
UVM	Kinase	ROCK1	TTBK2	0.869690266	1.25E-25
UVM	Kinase	ROCK1	PRKAA1	0.877897767	1.16E-26
UVM	Kinase	ROCK1	TLK1	0.885523388	1.09E-27
UVM	Kinase	ROCK1	SCYL2	0.887114073	6.52E-28
UVM	Kinase	ROCK1	TRPM7	0.901763105	3.84E-30
UVM	Kinase	ROCK1	NEK1	0.907638345	3.88E-31
UVM	Kinase	ROCK1	PRPF4B	0.912896468	4.37E-32
UVM	Kinase	ROCK1	RIOK3	0.915343312	1.51E-32
UVM	Kinase	ROCK1	MAP3K2	0.923230786	3.87E-34
UVM	Kinase	ROCK1	SMG1	0.930012544	1.20E-35
UVM	Kinase	ROCK1	SLK	0.954963365	6.57E-43
UVM	TF	ROCK1	ZNF17	0.800440824	5.14E-19
UVM	TF	ROCK1	ZNF143	0.803832781	2.82E-19
UVM	TF	ROCK1	PRMT3	0.804320672	2.59E-19
UVM	TF	ROCK1	TERF1	0.804813593	2.37E-19
UVM	TF	ROCK1	ZNF546	0.805320198	2.16E-19
UVM	TF	ROCK1	NFE2L2	0.806399927	1.78E-19
UVM	TF	ROCK1	ZNF302	0.807732675	1.40E-19
UVM	TF	ROCK1	ZNF320	0.808490317	1.22E-19
UVM	TF	ROCK1	RORA	0.808725887	1.16E-19
UVM	TF	ROCK1	ZNF765	0.809045442	1.10E-19
UVM	TF	ROCK1	ZBTB44	0.810195053	8.88E-20
UVM	TF	ROCK1	ZNF493	0.810495993	8.40E-20
UVM	TF	ROCK1	ZNF184	0.811697691	6.72E-20
UVM	TF	ROCK1	YY1	0.812098067	6.23E-20
UVM	TF	ROCK1	ZFP14	0.812474222	5.81E-20
UVM	TF	ROCK1	ZNF829	0.812825618	5.44E-20
UVM	TF	ROCK1	ZNF14	0.813143792	5.12E-20
UVM	TF	ROCK1	ZSCAN29	0.813168158	5.10E-20
UVM	TF	ROCK1	RFX7	0.814307254	4.11E-20
UVM	TF	ROCK1	NR3C1	0.816233441	2.85E-20
UVM	TF	ROCK1	ZNF12	0.816797828	2.55E-20
UVM	TF	ROCK1	ZNF470	0.817153105	2.38E-20
UVM	TF	ROCK1	ZNF84	0.817468072	2.24E-20
UVM	TF	ROCK1	ZNF10	0.817526879	2.22E-20
UVM	TF	ROCK1	ZNF813	0.817835549	2.09E-20
UVM	TF	ROCK1	GABPA	0.81818108	1.95E-20
UVM	TF	ROCK1	ZNF440	0.818358815	1.89E-20
UVM	TF	ROCK1	ZNF420	0.818533706	1.82E-20
UVM	TF	ROCK1	ASH1L	0.818889329	1.70E-20
UVM	TF	ROCK1	ZNF45	0.818961894	1.68E-20
UVM	TF	ROCK1	ZBTB6	0.819008828	1.66E-20
UVM	TF	ROCK1	ZC3H8	0.819595533	1.48E-20
UVM	TF	ROCK1	ZNF383	0.819787397	1.43E-20
UVM	TF	ROCK1	ZNF23	0.820589769	1.22E-20
UVM	TF	ROCK1	ZNF468	0.821498831	1.02E-20
UVM	TF	ROCK1	ZNF566	0.821580171	1.00E-20
UVM	TF	ROCK1	RLF	0.822301582	8.68E-21
UVM	TF	ROCK1	ZNF44	0.823087014	7.42E-21
UVM	TF	ROCK1	ZNF253	0.82365702	6.62E-21
UVM	TF	ROCK1	ZNF569	0.824828078	5.23E-21
UVM	TF	ROCK1	ZNF354B	0.82522441	4.83E-21
UVM	TF	ROCK1	ZNF606	0.825309384	4.74E-21
UVM	TF	ROCK1	VEZF1	0.826183517	3.97E-21
UVM	TF	ROCK1	ZNF280C	0.826394056	3.80E-21
UVM	TF	ROCK1	MGA	0.826950902	3.39E-21
UVM	TF	ROCK1	ZNF527	0.827116342	3.28E-21
UVM	TF	ROCK1	ZNF587	0.828381452	2.53E-21
UVM	TF	ROCK1	THAP9	0.828661397	2.38E-21
UVM	TF	ROCK1	HIF1A	0.828883121	2.28E-21
UVM	TF	ROCK1	TET2	0.830106105	1.76E-21
UVM	TF	ROCK1	ZBTB41	0.830322915	1.69E-21
UVM	TF	ROCK1	ZNF141	0.831785474	1.24E-21
UVM	TF	ROCK1	ZNF780A	0.831846531	1.22E-21
UVM	TF	ROCK1	ZNF182	0.832693004	1.02E-21
UVM	TF	ROCK1	ZNF658	0.832742656	1.01E-21
UVM	TF	ROCK1	ZBED5	0.833083173	9.40E-22
UVM	TF	ROCK1	ZNF451	0.833652037	8.32E-22
UVM	TF	ROCK1	PURB	0.833773345	8.11E-22
UVM	TF	ROCK1	ZNF678	0.83447603	6.97E-22
UVM	TF	ROCK1	NR2C1	0.834633103	6.74E-22
UVM	TF	ROCK1	ZNF91	0.835222383	5.93E-22
UVM	TF	ROCK1	ZNF449	0.835819705	5.21E-22
UVM	TF	ROCK1	ZNF26	0.836210846	4.79E-22
UVM	TF	ROCK1	ZNF700	0.837480364	3.62E-22
UVM	TF	ROCK1	ZNF260	0.837643237	3.50E-22
UVM	TF	ROCK1	ZNF708	0.839059089	2.56E-22
UVM	TF	ROCK1	ZNF81	0.83927562	2.44E-22
UVM	TF	ROCK1	JRKL	0.840577243	1.82E-22
UVM	TF	ROCK1	ZNF347	0.841025072	1.65E-22
UVM	TF	ROCK1	ADNP2	0.841666979	1.42E-22
UVM	TF	ROCK1	ZNF761	0.842186124	1.27E-22
UVM	TF	ROCK1	ZNF585B	0.842691232	1.13E-22
UVM	TF	ROCK1	ZNF782	0.843024255	1.05E-22
UVM	TF	ROCK1	SKIL	0.843316568	9.79E-23
UVM	TF	ROCK1	ZNF558	0.84385694	8.65E-23
UVM	TF	ROCK1	ZNF148	0.845305586	6.19E-23
UVM	TF	ROCK1	ZNF146	0.84539916	6.05E-23
UVM	TF	ROCK1	BPTF	0.845928622	5.35E-23
UVM	TF	ROCK1	SP4	0.845947019	5.33E-23
UVM	TF	ROCK1	ZNF160	0.848293552	3.07E-23
UVM	TF	ROCK1	ZNF484	0.849055542	2.56E-23
UVM	TF	ROCK1	AEBP2	0.849514385	2.30E-23
UVM	TF	ROCK1	SMAD4	0.850085485	2.00E-23
UVM	TF	ROCK1	ZBTB11	0.850685226	1.73E-23
UVM	TF	ROCK1	ZNF518A	0.850778245	1.69E-23
UVM	TF	ROCK1	ZNF845	0.851267599	1.50E-23
UVM	TF	ROCK1	ZNF432	0.852744833	1.05E-23
UVM	TF	ROCK1	ZNF236	0.852766394	1.04E-23
UVM	TF	ROCK1	ZNF268	0.853867985	7.97E-24
UVM	TF	ROCK1	ZNF644	0.854349846	7.07E-24
UVM	TF	ROCK1	ATF1	0.854544072	6.74E-24
UVM	TF	ROCK1	ARID2	0.855339533	5.53E-24
UVM	TF	ROCK1	ZNF701	0.855429993	5.40E-24
UVM	TF	ROCK1	CREBZF	0.856122994	4.54E-24
UVM	TF	ROCK1	ZNF292	0.856967223	3.67E-24
UVM	TF	ROCK1	BACH1	0.857227116	3.44E-24
UVM	TF	ROCK1	ZNF625	0.857791087	2.98E-24
UVM	TF	ROCK1	ZNF780B	0.859813279	1.77E-24
UVM	TF	ROCK1	RBAK	0.86095182	1.32E-24
UVM	TF	ROCK1	ZNF75D	0.861482457	1.15E-24
UVM	TF	ROCK1	ZNF254	0.8617509	1.07E-24
UVM	TF	ROCK1	ZNF180	0.862224552	9.46E-25
UVM	TF	ROCK1	SMAD5	0.862436675	8.95E-25
UVM	TF	ROCK1	ZNF567	0.862792087	8.15E-25
UVM	TF	ROCK1	IKZF5	0.863030707	7.65E-25
UVM	TF	ROCK1	MYSM1	0.863223497	7.27E-25
UVM	TF	ROCK1	ELF2	0.863930558	6.02E-25
UVM	TF	ROCK1	ZNF770	0.865568464	3.88E-25
UVM	TF	ROCK1	ZNF43	0.865599406	3.85E-25
UVM	TF	ROCK1	ZNF721	0.865880504	3.56E-25
UVM	TF	ROCK1	ATF2	0.866483558	3.03E-25
UVM	TF	ROCK1	ZNF280D	0.867276012	2.44E-25
UVM	TF	ROCK1	ZNF131	0.867969582	2.01E-25
UVM	TF	ROCK1	ZNF674	0.868063139	1.96E-25
UVM	TF	ROCK1	ELF1	0.868412799	1.78E-25
UVM	TF	ROCK1	ZNF611	0.868500608	1.74E-25
UVM	TF	ROCK1	ZNF234	0.869780573	1.22E-25
UVM	TF	ROCK1	DMTF1	0.869939376	1.16E-25
UVM	TF	ROCK1	ZNF248	0.870526065	9.88E-26
UVM	TF	ROCK1	ZNF25	0.870751812	9.27E-26
UVM	TF	ROCK1	ZNF326	0.870811105	9.12E-26
UVM	TF	ROCK1	ZNF136	0.873165689	4.66E-26
UVM	TF	ROCK1	ZNF675	0.873286042	4.50E-26
UVM	TF	ROCK1	PRDM10	0.873709765	3.98E-26
UVM	TF	ROCK1	GPBP1	0.874343822	3.31E-26
UVM	TF	ROCK1	ZNF267	0.874577868	3.10E-26
UVM	TF	ROCK1	ZNF195	0.874930313	2.79E-26
UVM	TF	ROCK1	ZNF431	0.875251232	2.54E-26
UVM	TF	ROCK1	LIN54	0.875818094	2.15E-26
UVM	TF	ROCK1	ELK3	0.877377446	1.36E-26
UVM	TF	ROCK1	HDX	0.878186591	1.06E-26
UVM	TF	ROCK1	THAP6	0.878971542	8.40E-27
UVM	TF	ROCK1	ZNF510	0.879028991	8.26E-27
UVM	TF	ROCK1	ZNF181	0.87916165	7.93E-27
UVM	TF	ROCK1	LCOR	0.879722389	6.69E-27
UVM	TF	ROCK1	EEA1	0.880357391	5.51E-27
UVM	TF	ROCK1	THAP5	0.881460041	3.92E-27
UVM	TF	ROCK1	CREB1	0.88241869	2.91E-27
UVM	TF	ROCK1	ZBTB1	0.882845295	2.55E-27
UVM	TF	ROCK1	NFXL1	0.883324033	2.19E-27
UVM	TF	ROCK1	ZNF41	0.885729751	1.02E-27
UVM	TF	ROCK1	CLOCK	0.887177761	6.38E-28
UVM	TF	ROCK1	CEBPZ	0.887434834	5.87E-28
UVM	TF	ROCK1	ZNF441	0.890234308	2.32E-28
UVM	TF	ROCK1	ZNF37A	0.894314232	5.74E-29
UVM	TF	ROCK1	AHCTF1	0.894959592	4.58E-29
UVM	TF	ROCK1	REST	0.896878382	2.32E-29
UVM	TF	ROCK1	BAZ2B	0.899450483	9.09E-30
UVM	TF	ROCK1	ZNF800	0.899502053	8.92E-30
UVM	TF	ROCK1	TMF1	0.900297828	6.64E-30
UVM	TF	ROCK1	ZNF28	0.900735256	5.64E-30
UVM	TF	ROCK1	TOPORS	0.900799856	5.51E-30
UVM	TF	ROCK1	SP3	0.902161911	3.30E-30
UVM	TF	ROCK1	MEF2A	0.902565434	2.83E-30
UVM	TF	ROCK1	ZFX	0.902794498	2.59E-30
UVM	TF	ROCK1	ZNF33A	0.909224443	2.04E-31
UVM	TF	ROCK1	ZNF397	0.91201171	6.37E-32
UVM	TF	ROCK1	ZNF791	0.922133089	6.59E-34
UVM	TF	ROCK1	ZNF430	0.930397732	9.72E-36
UVM	TSG	ROCK1	PAWR	0.800510754	5.07E-19
UVM	TSG	ROCK1	COPS2	0.805191368	2.21E-19
UVM	TSG	ROCK1	CDKN1B	0.807048421	1.58E-19
UVM	TSG	ROCK1	USP33	0.809474971	1.01E-19
UVM	TSG	ROCK1	ANXA7	0.810213673	8.85E-20
UVM	TSG	ROCK1	RINT1	0.810730209	8.04E-20
UVM	TSG	ROCK1	NAPEPLD	0.812139058	6.18E-20
UVM	TSG	ROCK1	TRIM24	0.812925231	5.33E-20
UVM	TSG	ROCK1	RBL1	0.813313679	4.96E-20
UVM	TSG	ROCK1	PTPN12	0.815526976	3.26E-20
UVM	TSG	ROCK1	GTPBP4	0.822472601	8.39E-21
UVM	TSG	ROCK1	PNN	0.822856241	7.77E-21
UVM	TSG	ROCK1	BMPR1A	0.826023235	4.10E-21
UVM	TSG	ROCK1	SIRT1	0.826052438	4.08E-21
UVM	TSG	ROCK1	HIF1A	0.828883121	2.28E-21
UVM	TSG	ROCK1	TET2	0.830106105	1.76E-21
UVM	TSG	ROCK1	MLH3	0.834079022	7.59E-22
UVM	TSG	ROCK1	CHUK	0.835551165	5.52E-22
UVM	TSG	ROCK1	LIN9	0.836838813	4.17E-22
UVM	TSG	ROCK1	PTPN11	0.838779985	2.72E-22
UVM	TSG	ROCK1	FAM188A	0.839050419	2.56E-22
UVM	TSG	ROCK1	GGNBP2	0.839384892	2.38E-22
UVM	TSG	ROCK1	RB1	0.839862412	2.14E-22
UVM	TSG	ROCK1	MSH2	0.840747906	1.75E-22
UVM	TSG	ROCK1	SKIL	0.843316568	9.79E-23
UVM	TSG	ROCK1	USP12	0.843541455	9.30E-23
UVM	TSG	ROCK1	DCLRE1A	0.846200119	5.02E-23
UVM	TSG	ROCK1	KDM5A	0.849728346	2.18E-23
UVM	TSG	ROCK1	SMAD4	0.850085485	2.00E-23
UVM	TSG	ROCK1	SHPRH	0.853297521	9.17E-24
UVM	TSG	ROCK1	ARID2	0.855339533	5.53E-24
UVM	TSG	ROCK1	UHRF2	0.855366699	5.49E-24
UVM	TSG	ROCK1	ZNF292	0.856967223	3.67E-24
UVM	TSG	ROCK1	NEDD4	0.857551794	3.17E-24
UVM	TSG	ROCK1	ATM	0.857906834	2.89E-24
UVM	TSG	ROCK1	APAF1	0.859575679	1.89E-24
UVM	TSG	ROCK1	RBBP8	0.860640882	1.43E-24
UVM	TSG	ROCK1	GORAB	0.860684016	1.42E-24
UVM	TSG	ROCK1	BRCA2	0.860841934	1.36E-24
UVM	TSG	ROCK1	BMPR2	0.863828877	6.19E-25
UVM	TSG	ROCK1	PPM1A	0.864295305	5.46E-25
UVM	TSG	ROCK1	DMTF1	0.869939376	1.16E-25
UVM	TSG	ROCK1	ITGAV	0.870401084	1.02E-25
UVM	TSG	ROCK1	TANK	0.87347709	4.26E-26
UVM	TSG	ROCK1	ZMYND11	0.875099705	2.66E-26
UVM	TSG	ROCK1	PRKAA1	0.877897767	1.16E-26
UVM	TSG	ROCK1	CHD1	0.880914695	4.64E-27
UVM	TSG	ROCK1	PHF6	0.883233104	2.26E-27
UVM	TSG	ROCK1	CDC73	0.887716388	5.35E-28
UVM	TSG	ROCK1	APC	0.890110244	2.42E-28
UVM	TSG	ROCK1	PDS5B	0.893322466	8.10E-29
UVM	TSG	ROCK1	INTS6	0.897631594	1.77E-29
UVM	TSG	ROCK1	DICER1	0.898400162	1.34E-29
UVM	TSG	ROCK1	TOPORS	0.900799856	5.51E-30
UVM	TSG	ROCK1	WDR11	0.901344758	4.49E-30
UVM	TSG	ROCK1	VEZT	0.901682635	3.96E-30
UVM	TSG	ROCK1	SMCHD1	0.902183354	3.27E-30
UVM	TSG	ROCK1	RB1CC1	0.904537164	1.32E-30
UVM	TSG	ROCK1	KRIT1	0.905032508	1.09E-30
UVM	TSG	ROCK1	CUL2	0.910297249	1.31E-31
UVM	TSG	ROCK1	SUZ12	0.915581045	1.36E-32
UVM	TSG	ROCK1	CUL5	0.934391561	1.05E-36
UVM	TSG	ROCK1	CCAR1	0.94139114	1.47E-38

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LUSC	ROCK1	RND3	1.04818253915572	0.000102202753672845
THCA	ROCK1	ROCK2	2.71750472590242	0.000116564205786803
COAD	ROCK1	CDC42	-2.2640573059658	0.000125885009765625
KICH	ROCK1	CASP3	-1.33579752215497	0.000187873840332031
BLCA	ROCK1	RND3	-1.46994698351353	0.000335693359375
PRAD	ROCK1	RHOC	-1.55096053845514	0.000431834371694536
LUSC	ROCK1	CDC42	-1.32952300607616	0.000431975220131112
KIRP	ROCK1	LIMK2	1.05635499730027	0.000837184488773346
KIRC	ROCK1	CDC42	-1.22188486751084	0.00220467399393826
KICH	ROCK1	RND3	2.60438944099854	0.00378090143203735
CHOL	ROCK1	LIMK2	-6.17541173871522	0.00390625
CHOL	ROCK1	PPP1R12A	-3.96213486529692	0.00390625
CHOL	ROCK1	RND3	-3.50360238513578	0.00390625
STAD	ROCK1	PPP1R12A	-1.97938788154196	0.0044123362749815
STAD	ROCK1	RHOA	-1.41193589695659	0.00471024587750435
BLCA	ROCK1	PPP1R12A	-2.78876802599308	0.0108261108398438
PRAD	ROCK1	ROCK2	-2.28263019505903	0.0148465704687343
COAD	ROCK1	RHOA	-1.35466527140618	0.0163331627845764
READ	ROCK1	CDC42	-2.89472372432256	0.03125
COAD	ROCK1	RND3	-1.03108570831106	0.0381683111190796
BLCA	ROCK1	MSN	2.36130843801471	0.0493659973144531
STAD	ROCK1	MYL9	-1.84221346281728	1.26352533698082e-05
BRCA	ROCK1	CDC42	1.53775410810954	1.344517500009e-07
LIHC	ROCK1	RHOA	-1.12608618743874	1.38856254833826e-06
KIRC	ROCK1	CASP3	-1.13788607606139	1.47934674983518e-09
PRAD	ROCK1	RHOA	1.24204655661997	1.48677209176304e-06
COAD	ROCK1	RHOC	-2.63461423971247	1.59740447998047e-05
BRCA	ROCK1	PPP1R12A	-1.60156833405818	1.79190012161022e-11
BRCA	ROCK1	MYL9	-2.18745415094576	1.91865153760163e-27
KIRP	ROCK1	CASP3	-1.47815796439668	2.00234353542328e-08
LUSC	ROCK1	ROCK2	-1.24167488117902	2.12944383491207e-05
PRAD	ROCK1	PPP1R12A	-1.3153988861503	2.48181746506057e-07
LUSC	ROCK1	MSN	-1.4367568231783	2.88359523303561e-09
LUSC	ROCK1	LIMK2	1.23299237893353	3.22267019689868e-05
BRCA	ROCK1	ROCK2	-1.34452718141111	3.31419056854665e-18
COAD	ROCK1	MYL9	-3.19227180683107	3.75509262084961e-05
THCA	ROCK1	LIMK2	-2.89731784986581	4.81463501802485e-09
LIHC	ROCK1	RND3	-4.68514746510352	4.91907449309094e-09
LUAD	ROCK1	MYL9	-3.05036819646449	5.18546916374703e-11
LUAD	ROCK1	RHOA	-1.27824636836466	5.24732369463512e-07
HNSC	ROCK1	RHOC	-4.29010025717605	6.4983867105184e-06
COAD	ROCK1	LIMK2	-1.4207577176118	7.02440738677979e-05
LUSC	ROCK1	MYL9	-6.11032298470584	7.13549502039471e-10
BLCA	ROCK1	MYL9	-4.01331178754516	7.2479248046875e-05
THCA	ROCK1	MSN	1.85295259059071	9.49745750919905e-10

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with ROCK1

CDC25A, PFN2, RHOA, RND3, GAB1, CFL1, LIMK2, HNRNPA1, ITSN2, ARRB1, TSG101, NOTCH1, SMURF1, SMAD2, CASP3, CASP7, CDK15, ANKFY1, MON2, FAM21A, KIAA1033, IKBKB, LMO2, MAGEB4, POLR3C, C6orf165, FAM124A, NXF1, NTRK1, MED23, XRCC5, NEIL3, Smad3, Snap29, Dync1li1, TRIM15, HGS, SLC9A1, UBE2T, CDKN3, TENC1, ROCK2, ADD2, IL20RA, CYLD, UBE2M, HRAS, KRAS, NRAS, MLC1, LAMP1, KIAA1429, TPPP, PLEKHA4, RHOBTB1, ELK4, PRKAR1A, PXN, RAB5A, S, ANLN, BRD4, YWHAE, CUL4A, KDM4D, TAF4, CHERP, UFL1, TP53, LINC00452, ARF6, FLOT1, IMPDH2, LAMP2, LAMP3, LAMTOR1, LYN, MLLT4, RAB2A, RAB35, RAB4A, RHOB, EDEM1, HMGB2, CERS2, HTRA3, SYCE1, AHR, ANKRD49, FECH, ANAPC16, SMAD4, ZBTB2, MED17, SPRTN, ATP6V0A1, BBS1, PHKA2, EP300, ANPEP, DPP4, IFITM3, TMPRSS11B, SMAD5, RHOC,

Top

Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
ROCK1	chr18	18535142	G	A	single_nucleotide_variant	Likely_pathogenic	Breast_neoplasm\|Lung_carcinoma	SO:0001583\|missense_variant	SO:0001583\|missense_variant
ROCK1	chr18	18550353	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
ROCK1	chr18	18550477	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
ROCK1	chr18	18564483	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
ROCK1	chr18	18586412	A	C	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
ROCK1	chr18	18619425	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
ROCK1	chr18	18622614	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
ROCK1	PCPG	chr18	18534948	18534948	G	C	Missense_Mutation	p.Q1217E	6
ROCK1	COAD	chr18	18629104	18629105	-	A	Frame_Shift_Ins	p.F121fs	5
ROCK1	LUAD	chr18	18622649	18622649	T	C	Missense_Mutation	p.T233A	5
ROCK1	STAD	chr18	18533679	18533679	T	-	Frame_Shift_Del	p.K1307fs	5
ROCK1	LUAD	chr18	18550453	18550453	C	A	Missense_Mutation	p.L892F	5
ROCK1	ESCA	chr18	18608786	18608786	C	T	Missense_Mutation	p.V388I	4
ROCK1	LIHC	chr18	18534827	18534827	G	-	Frame_Shift_Del	p.P1257fs	4
ROCK1	BRCA	chr18	18586384	18586384	G	A	Nonsense_Mutation	p.Q605*	4
ROCK1	BLCA	chr18	18547870	18547870	C	T	Missense_Mutation	p.R1012Q	4
ROCK1	PAAD	chr18	18562785	18562785	C	T	Missense_Mutation	p.R833K	3
ROCK1	PAAD	chr18	18588085	18588085	C	A	Missense_Mutation	p.R494I	3
ROCK1	GBM	chr18	18533573	18533573	G	A	Missense_Mutation	p.R1343W	3
ROCK1	ACC	chr18	18629131	18629131	C	T	Missense_Mutation	p.M112I	3
ROCK1	ESCA	chr18	18547850	18547850	T	C	Missense_Mutation	p.R1019G	3
ROCK1	LIHC	chr18	18559877	18559877	T	-	Frame_Shift_Del	p.N883fs	3
ROCK1	ESCA	chr18	18559913	18559913	T	G	Missense_Mutation	p.N871T	3
ROCK1	PAAD	chr18	18625398	18625398	G	A	Missense_Mutation	p.L149F	3
ROCK1	BLCA	chr18	18622100	18622100	G	C	Nonsense_Mutation	p.S306*	3
ROCK1	LGG	chr18	18586428	18586428	C	T	Missense_Mutation	p.R590Q	3
ROCK1	PRAD	chr18	18625328	18625328	T	C	Missense_Mutation	p.E172G	3
ROCK1	KIRC	chr18	18629104	18629105	-	A	Frame_Shift_Ins	p.L121fs	3
ROCK1	HNSC	chr18	18534911	18534911	T	C	Missense_Mutation	p.H1229R	3
ROCK1	SKCM	chr18	18534797	18534797	T	A	Missense_Mutation	p.K1267M	2
ROCK1	HNSC	chr18	18547018	18547018	G	A	Missense_Mutation	p.A1071V	2
ROCK1	UCEC	chr18	18608876	18608876	C	T	Missense_Mutation	p.D358N	2
ROCK1	LIHC	chr18	18629105	18629105	A	-	Frame_Shift_Del	p.F121fs	2
ROCK1	LUAD	chr18	18586533	18586533	C	G	Missense_Mutation	p.R555T	2
ROCK1	PRAD	chr18	18533607	18533607	C	T	Silent	p.T1331T	2
ROCK1	BLCA	chr18	18690843	18690843	C	A	Missense_Mutation		2
ROCK1	BRCA	chr18	18539823	18539823	G	A	Missense_Mutation	p.P1164S	2
ROCK1	UCEC	chr18	18547829	18547829	C	A	Missense_Mutation	p.D1026Y	2
ROCK1	LUAD	chr18	18539817	18539817	T	C	Missense_Mutation	p.M1166V	2
ROCK1	SKCM	chr18	18629177	18629177	G	A	Missense_Mutation	p.S97F	2
ROCK1	UCEC	chr18	18619434	18619434	G	A	Silent	p.D350	2
ROCK1	PRAD	chr18	18690838	18690839	-	AAA	In_Frame_Ins	p.11_12insF	2
ROCK1	SARC	chr18	18566975	18566975	T	C	Missense_Mutation		2
ROCK1	STAD	chr18	18564319	18564319	G	A	Missense_Mutation	p.L828F	2
ROCK1	BRCA	chr18	18572891	18572891	A	G	Silent	p.I631	2
ROCK1	STAD	chr18	18546911	18546911	G	C	Missense_Mutation	p.P1107A	2
ROCK1	UCEC	chr18	18547865	18547865	C	A	Missense_Mutation	p.D1014Y	2
ROCK1	LUAD	chr18	18650556	18650556	C	A	Missense_Mutation	p.V38L	2
ROCK1	PAAD	chr18	18622107	18622107	C	T	Missense_Mutation	p.D304N	2
ROCK1	SKCM	chr18	18550323	18550323	G	A	Missense_Mutation	p.H936Y	2
ROCK1	CESC	chr18	18586468	18586468	G	A	Nonsense_Mutation	p.Q577*	2
ROCK1	KIRC	chr18	18586538	18586538	T	A	Missense_Mutation	p.L553F	2
ROCK1	UCEC	chr18	18619483	18619483	C	T	Missense_Mutation	p.R334Q	2
ROCK1	PRAD	chr18	18586746	18586746	T	A	Missense_Mutation	p.T518S	2
ROCK1	STAD	chr18	18533607	18533607	C	T	Silent		2
ROCK1	BLCA	chr18	18549123	18549123	C	G	Missense_Mutation	p.R956T	2
ROCK1	STAD	chr18	18547719	18547719	C	T	Missense_Mutation	p.M1062I	2
ROCK1	BRCA	chr18	18586456	18586456	G	C	Missense_Mutation	p.L581V	2
ROCK1	STAD	chr18	18566911	18566911	T	G	Missense_Mutation	p.E768D	2
ROCK1	UCEC	chr18	18564314	18564314	C	T	Silent	p.T829	2
ROCK1	LUAD	chr18	18622550	18622550	C	-	Frame_Shift_Del	p.V266fs	2
ROCK1	UCEC	chr18	18629082	18629082	C	T	Missense_Mutation	p.A129T	2
ROCK1	HNSC	chr18	18566941	18566941	C	G	Missense_Mutation	p.L758F	2
ROCK1	BLCA	chr18	18629788	18629788	C	T	Missense_Mutation	p.E77K	2
ROCK1	STAD	chr18	18619444	18619444	G	A	Missense_Mutation	p.T347M	2
ROCK1	HNSC	chr18	18600198	18600198	C	A	Missense_Mutation	p.Q425H	2
ROCK1	UCEC	chr18	18564337	18564337	C	A	Nonsense_Mutation	p.E822*	2
ROCK1	LIHC	chr18	18566933	18566933	T	-	Frame_Shift_Del	p.N761fs	2
ROCK1	SKCM	chr18	18625312	18625312	G	A	Silent	p.F177F	2
ROCK1	UCEC	chr18	18629794	18629794	C	T	Missense_Mutation	p.D75N	2
ROCK1	HNSC	chr18	18586476	18586476	G	A	Missense_Mutation	p.S574L	2
ROCK1	LIHC	chr18	18586398	18586398	T	G	Missense_Mutation		2
ROCK1	STAD	chr18	18564356	18564356	C	T	Silent	p.L815L	2
ROCK1	HNSC	chr18	18572799	18572799	G	A	Missense_Mutation	p.S662L	2
ROCK1	UCEC	chr18	18566915	18566915	T	C	Missense_Mutation	p.D767G	2
ROCK1	LIHC	chr18	18572839	18572839	C	-	Frame_Shift_Del	p.E649fs	2
ROCK1	PAAD	chr18	18625398	18625398	G	A	Missense_Mutation		2
ROCK1	PAAD	chr18	18608802	18608802	A	-	Frame_Shift_Del	p.P382fs	2
ROCK1	SKCM	chr18	18622602	18622602	G	A	Silent	p.S248S	2
ROCK1	KIRC	chr18	18549140	18549140	T	G	Missense_Mutation	p.K950N	2
ROCK1	UCEC	chr18	18629808	18629808	C	T	Missense_Mutation	p.R70Q	2
ROCK1	HNSC	chr18	18534783	18534783	G	T	Missense_Mutation	p.H1272N	2
ROCK1	LIHC	chr18	18559965	18559965	T	C	Missense_Mutation		2
ROCK1	LUAD	chr18	18534823	18534823	G	C	Silent	p.A1258A	2
ROCK1	READ	chr18	18550366	18550366	C	A	Missense_Mutation	p.K921N	2
ROCK1	SARC	chr18	18566975	18566975	T	C	Missense_Mutation	p.D747G	2
ROCK1	CESC	chr18	18539802	18539802	C	G	Missense_Mutation		2
ROCK1	HNSC	chr18	18629114	18629114	G	A	Missense_Mutation	p.S118F	2
ROCK1	UCEC	chr18	18571203	18571203	C	A	Missense_Mutation	p.V693L	2
ROCK1	LIHC	chr18	18608766	18608766	A	-	Frame_Shift_Del	p.F394fs	2
ROCK1	LUAD	chr18	18629083	18629083	C	A	Missense_Mutation	p.M128I	2
ROCK1	UCEC	chr18	18629823	18629823	T	A	Missense_Mutation	p.K65I	2
ROCK1	STAD	chr18	18539829	18539829	A	G	Missense_Mutation	p.S1162P	2
ROCK1	CESC	chr18	18562727	18562727	G	A	Silent		2
ROCK1	ESCA	chr18	18622641	18622641	A	G	Silent		2
ROCK1	UCEC	chr18	18572881	18572881	G	A	Nonsense_Mutation	p.Q635*	2
ROCK1	LIHC	chr18	18629179	18629179	T	-	Frame_Shift_Del	p.K96fs	2
ROCK1	PAAD	chr18	18588085	18588085	C	A	Missense_Mutation		2
ROCK1	PRAD	chr18	18546946	18546946	A	G	Missense_Mutation	p.L1095S	2
ROCK1	TGCT	chr18	18586412	18586412	A	C	Silent		2
ROCK1	UCEC	chr18	18629824	18629824	T	C	Missense_Mutation	p.K65E	2
ROCK1	UCEC	chr18	18533559	18533559	T	G	Missense_Mutation	p.K1347N	2
ROCK1	LIHC	chr18	18586398	18586398	T	G	Missense_Mutation	p.D600A	2
ROCK1	LUAD	chr18	18600168	18600168	C	A	Silent	p.L435L	2
ROCK1	STAD	chr18	18629104	18629104	G	-	Frame_Shift_Del	p.W122fs	2
ROCK1	SKCM	chr18	18564360	18564360	A	G	Missense_Mutation	p.L814S	2
ROCK1	ESCA	chr18	18559913	18559913	T	G	Missense_Mutation		2
ROCK1	UCEC	chr18	18572895	18572895	C	T	Missense_Mutation	p.R630Q	2
ROCK1	CHOL	chr18	18629827	18629827	T	A	Missense_Mutation		2
ROCK1	BLCA	chr18	18625257	18625257	G	A	Missense_Mutation	p.H196Y	2
ROCK1	UCEC	chr18	18533611	18533611	C	T	Missense_Mutation	p.R1330Q	2
ROCK1	LIHC	chr18	18690859	18690859	C	-	Frame_Shift_Del	p.D5fs	2
ROCK1	LUAD	chr18	18549153	18549153	C	T	Missense_Mutation	p.S946N	2
ROCK1	STAD	chr18	18586553	18586553	T	A	Missense_Mutation	p.E548D	2
ROCK1	ESCA	chr18	18547850	18547850	T	C	Missense_Mutation		2
ROCK1	HNSC	chr18	18535194	18535194	G	C	Missense_Mutation	p.H1175Q	2
ROCK1	UCEC	chr18	18595406	18595406	C	A	Nonsense_Mutation	p.E466*	2
ROCK1	CHOL	chr18	18629827	18629827	T	A	Missense_Mutation	p.N64Y	2
ROCK1	THYM	chr18	18549120	18549120	C	A	Missense_Mutation		2
ROCK1	STAD	chr18	18588031	18588031	A	G	Missense_Mutation	p.V512A	2
ROCK1	HNSC	chr18	18622625	18622625	T	C	Missense_Mutation	p.I241V	2
ROCK1	UCEC	chr18	18539847	18539847	C	T	Missense_Mutation	p.E1156K	2
ROCK1	SKCM	chr18	18534804	18534804	G	A	Missense_Mutation	p.H1265Y	2
ROCK1	CESC	chr18	18571173	18571173	G	C	Missense_Mutation		2
ROCK1	ESCA	chr18	18622641	18622641	A	G	Silent	p.V235V	2
ROCK1	HNSC	chr18	18629142	18629142	T	C	Missense_Mutation	p.K109E	2
ROCK1	UCEC	chr18	18603609	18603609	C	A	Missense_Mutation	p.R415I	2
ROCK1	LUSC	chr18	18533574	18533574	G	A	Silent	p.F1342F	2
ROCK1	HNSC	chr18	18548731	18548731	A	G	Splice_Site		2
ROCK1	BRCA	chr18	18534990	18534990	C	T	Missense_Mutation	p.E1203K	2
ROCK1	COAD	chr18	18622543	18622543	A	-	Frame_Shift_Del	p.L268fs	2
ROCK1	STAD	chr18	18564452	18564452	C	T	Silent	p.R783R	2
ROCK1	UCEC	chr18	18546980	18546980	C	A	Nonsense_Mutation	p.E1084*	2
ROCK1	STAD	chr18	18622132	18622132	A	T	Missense_Mutation	p.N295K	2
ROCK1	CESC	chr18	18539802	18539802	C	G	Splice_Site	p.D1171_splice	1
ROCK1	HNSC	chr18	18629114	18629114	G	A	Missense_Mutation		1
ROCK1	STAD	chr18	18624112	18624112	G	T	Missense_Mutation	p.S209Y	1
ROCK1	MESO	chr18	18572816	18572817	TT	-	Frame_Shift_Del		1
ROCK1	LIHC	chr18	18629110	18629110	A	G	Silent		1
ROCK1	SKCM	chr18	18586524	18586524	G	T	Nonsense_Mutation	p.S558*	1
ROCK1	COAD	chr18	18534813	18534813	G	A	Nonsense_Mutation	p.R1262X	1
ROCK1	HNSC	chr18	18608856	18608856	A	G	Silent		1
ROCK1	THYM	chr18	18567025	18567025	A	G	Silent		1
ROCK1	KIRP	chr18	18624118	18624118	T	A	Missense_Mutation	p.D207V	1
ROCK1	STAD	chr18	18619431	18619431	A	G	Splice_Site	.	1
ROCK1	HNSC	chr18	18549116	18549116	C	G	Missense_Mutation	p.E958D	1
ROCK1	LIHC	chr18	18559965	18559965	T	C	Splice_Site	p.T854_splice	1
ROCK1	SARC	chr18	18564451	18564451	G	T	Missense_Mutation		1
ROCK1	STAD	chr18	18586552	18586552	C	A	Nonsense_Mutation	p.E549X	1
ROCK1	CESC	chr18	18562727	18562727	G	A	Silent	p.F852F	1
ROCK1	HNSC	chr18	18534783	18534783	G	T	Missense_Mutation		1
ROCK1	STAD	chr18	18619431	18619431	A	G	Splice_Site	p.T351_splice	1
ROCK1	HNSC	chr18	18624129	18624135	GTTATCA	-	Frame_Shift_Del	p.PDN201fs	1
ROCK1	LIHC	chr18	18534936	18534936	T	-	Frame_Shift_Del	p.T1221fs	1
ROCK1	MESO	chr18	18622574	18622574	C	T	Missense_Mutation		1
ROCK1	THYM	chr18	18571282	18571282	C	A	Missense_Mutation	p.K666N	1
ROCK1	KIRP	chr18	18600173	18600174	TA	-	Frame_Shift_Del	p.434_434del	1
ROCK1	LIHC	chr18	18571156	18571156	T	C	Silent		1
ROCK1	LUAD	chr18	18567066	18567066	C	A	Nonsense_Mutation	p.E717*	1
ROCK1	SKCM	chr18	18588072	18588072	G	A	Silent	p.Y498Y	1
ROCK1	BLCA	chr18	18595438	18595438	G	T	Missense_Mutation	p.T455N	1
ROCK1	COAD	chr18	18539864	18539865	-	T	Frame_Shift_Ins	p.I1150fs	1
ROCK1	HNSC	chr18	18547728	18547728	C	T	Silent		1
ROCK1	COAD	chr18	18547809	18547809	C	A	Missense_Mutation	p.K1032N	1
ROCK1	HNSC	chr18	18608840	18608840	C	T	Missense_Mutation	p.D370N	1
ROCK1	LIHC	chr18	18548738	18548738	T	-	Frame_Shift_Del	p.T1000fs	1
ROCK1	MESO	chr18	18622574	18622574	C	T	Missense_Mutation	p.E258K	1
ROCK1	HNSC	chr18	18625307	18625307	G	T	Missense_Mutation		1
ROCK1	STAD	chr18	18562783	18562783	C	A	Nonsense_Mutation	p.G834*	1
ROCK1	HNSC	chr18	18629092	18629092	C	A	Missense_Mutation		1
ROCK1	THYM	chr18	18567025	18567025	A	G	Silent	p.A730A	1
ROCK1	LGG	chr18	18546931	18546931	G	A	Missense_Mutation	p.S1100F	1
ROCK1	LIHC	chr18	18629763	18629763	C	T	Missense_Mutation		1
ROCK1	LUAD	chr18	18629053	18629053	C	A	Splice_Site	p.Q138_splice	1
ROCK1	COAD	chr18	18540139	18540139	T	C	Silent	p.V1127V	1
ROCK1	SARC	chr18	18550361	18550361	G	A	Missense_Mutation		1
ROCK1	GBM	chr18	18547745	18547745	T	A	Nonsense_Mutation	p.K1054*	1
ROCK1	HNSC	chr18	18608843	18608843	C	T	Missense_Mutation	p.D369N	1
ROCK1	LIHC	chr18	18559871	18559871	T	-	Splice_Site	p.K885_splice	1
ROCK1	MESO	chr18	18572816	18572817	TT	-	Frame_Shift_Del	p.Q656fs	1
ROCK1	PAAD	chr18	18608802	18608802	A	-	Frame_Shift_Del	p.I383fs	1
ROCK1	SKCM	chr18	18539819	18539819	G	A	Missense_Mutation	p.S1165F	1
ROCK1	ACC	chr18	18586509	18586509	C	A	Missense_Mutation	p.R563I	1
ROCK1	CESC	chr18	18586468	18586468	G	A	Nonsense_Mutation		1
ROCK1	HNSC	chr18	18622625	18622625	T	C	Missense_Mutation		1
ROCK1	STAD	chr18	18586552	18586552	C	A	Nonsense_Mutation	p.E549*	1
ROCK1	KIRC	chr18	18625289	18625289	G	A	Missense_Mutation	p.A185V	1
ROCK1	UCEC	chr18	18562764	18562764	C	T	Missense_Mutation	p.R840Q	1
ROCK1	LGG	chr18	18550345	18550345	T	C	Silent	p.R928R	1
ROCK1	LIHC	chr18	18533546	18533546	T	C	Missense_Mutation		1
ROCK1	LUAD	chr18	18586686	18586686	C	T	Missense_Mutation	p.E538K	1
ROCK1	READ	chr18	18534972	18534972	C	A	Missense_Mutation	p.D1209Y	1
ROCK1	STAD	chr18	18533679	18533679	T	-	Frame_Shift_Del	p.W1308fs	1
ROCK1	COAD	chr18	18547038	18547038	C	A	Splice_Site	.	1
ROCK1	SARC	chr18	18546910	18546910	G	T	Missense_Mutation		1
ROCK1	GBM	chr18	18547745	18547745	T	A	Nonsense_Mutation		1
ROCK1	STAD	chr18	18548822	18548822	C	T	Splice_Site		1
ROCK1	LUAD	chr18	18586524	18586524	G	A	Missense_Mutation	p.S558L	1
ROCK1	LIHC	chr18	18586718	18586718	T	-	Frame_Shift_Del	p.K528fs	1
ROCK1	PAAD	chr18	18562785	18562785	C	T	Missense_Mutation		1
ROCK1	BLCA	chr18	18595438	18595438	G	T	Missense_Mutation		1
ROCK1	CESC	chr18	18539802	18539802	C	G	Missense_Mutation	p.D1171H	1
ROCK1	HNSC	chr18	18549116	18549116	C	G	Missense_Mutation		1
ROCK1	STAD	chr18	18625286	18625287	-	AAA	In_Frame_Ins	p.L186F	1
ROCK1	KIRC	chr18	18608861	18608861	T	C	Missense_Mutation	p.I363V	1
ROCK1	UCEC	chr18	18571167	18571167	T	A	Missense_Mutation	p.I705F	1
ROCK1	LGG	chr18	18622660	18622660	A	G	Missense_Mutation	p.V229A	1
ROCK1	READ	chr18	18546988	18546988	G	T	Missense_Mutation	p.A1081D	1
ROCK1	COAD	chr18	18547714	18547714	G	A	Missense_Mutation	p.A1064V	1
ROCK1	SARC	chr18	18564451	18564451	G	T	Missense_Mutation	p.L784M	1
ROCK1	STAD	chr18	18622574	18622574	C	A	Nonsense_Mutation	p.E258X	1
ROCK1	CESC	chr18	18571139	18571139	C	G	Missense_Mutation		1
ROCK1	ESCA	chr18	18622641	18622641	A	G	Silent	p.V235	1
ROCK1	GBM	chr18	18548749	18548749	C	T	Missense_Mutation		1
ROCK1	STAD	chr18	18571244	18571244	G	C	Nonsense_Mutation	p.S679*	1
ROCK1	LUSC	chr18	18571194	18571194	C	T	Missense_Mutation	p.A696T	1
ROCK1	LIHC	chr18	18533628	18533628	A	-	Frame_Shift_Del	p.F1324fs	1
ROCK1	BLCA	chr18	18549123	18549123	C	G	Missense_Mutation		1
ROCK1	CESC	chr18	18571173	18571173	G	C	Missense_Mutation	p.Q703E	1
ROCK1	HNSC	chr18	18608840	18608840	C	T	Missense_Mutation		1
ROCK1	STAD	chr18	18629105	18629106	-	A	Frame_Shift_Ins	p.F121fs	1
ROCK1	UCEC	chr18	18539865	18539865	T	-	Frame_Shift_Del	p.I1150fs	1
ROCK1	LGG	chr18	18546978	18546978	C	T	Silent	p.E1084E	1
ROCK1	STAD	chr18	18533678	18533679	-	T	Frame_Shift_Ins	p.W1308fs	1
ROCK1	COAD	chr18	18559902	18559902	A	C	Missense_Mutation	p.L875V	1
ROCK1	STAD	chr18	18629740	18629740	C	T	Splice_Site	.	1
ROCK1	ESCA	chr18	18608786	18608786	C	T	Missense_Mutation		1
ROCK1	GBM	chr18	18549102	18549102	G	C	Missense_Mutation		1
ROCK1	LUSC	chr18	18608740	18608740	C	T	Missense_Mutation	p.R403H	1
ROCK1	PAAD	chr18	18608802	18608802	A	-	Frame_Shift_Del		1
ROCK1	SKCM	chr18	18608797	18608797	G	A	Missense_Mutation	p.P384L	1
ROCK1	BLCA	chr18	18629788	18629788	C	T	Missense_Mutation		1
ROCK1	CESC	chr18	18534772	18534772	C	T	Silent	p.K1275	1
ROCK1	HNSC	chr18	18608843	18608843	C	T	Missense_Mutation		1
ROCK1	STAD	chr18	18546954	18546954	A	G	Silent		1
ROCK1	KIRC	chr18	18624095	18624095	C	T	Missense_Mutation	p.A215T	1
ROCK1	COAD	chr18	18559913	18559913	T	-	Frame_Shift_Del	p.N871fs	1
ROCK1	HNSC	chr18	18625307	18625307	G	T	Missense_Mutation	p.T179N	1
ROCK1	UCEC	chr18	18533557	18533557	T	-	Frame_Shift_Del	p.N1348fs	1
ROCK1	LIHC	chr18	18625320	18625320	C	T	Missense_Mutation	p.A175T	1
ROCK1	READ	chr18	18629141	18629141	T	A	Missense_Mutation	p.K109I	1
ROCK1	BLCA	chr18	18546939	18546939	G	A	Silent	p.L1097L	1
ROCK1	SARC	chr18	18535007	18535007	T	G	Splice_Site		1
ROCK1	HNSC	chr18	18600198	18600198	C	A	Missense_Mutation		1
ROCK1	STAD	chr18	18586465	18586465	A	G	Silent	p.L578L	1
ROCK1	HNSC	chr18	18547728	18547728	C	T	Silent	p.L1059L	1
ROCK1	LUSC	chr18	18546931	18546931	G	C	Missense_Mutation	p.S1100C	1
ROCK1	LUAD	chr18	18624092	18624092	C	A	Missense_Mutation	p.D216Y	1
ROCK1	SKCM	chr18	18608798	18608798	G	A	Missense_Mutation	p.P384S	1
ROCK1	BLCA	chr18	18546939	18546939	G	A	Silent		1
ROCK1	CESC	chr18	18562727	18562727	G	A	Silent	p.F852	1
ROCK1	HNSC	chr18	18547018	18547018	G	A	Missense_Mutation		1
ROCK1	KIRC	chr18	18546995	18546995	G	A	Nonsense_Mutation	p.Q1079X	1
ROCK1	BLCA	chr18	18572886	18572886	G	C	Missense_Mutation	p.S633C	1
ROCK1	COAD	chr18	18595406	18595406	C	A	Nonsense_Mutation	p.E466X	1
ROCK1	STAD	chr18	18533679	18533680	TT	-	Frame_Shift_Del	p.1307_1308del	1
ROCK1	HNSC	chr18	18600179	18600179	T	A	Missense_Mutation	p.I432F	1
ROCK1	LGG	chr18	18586471	18586474	TAAT	-	Frame_Shift_Del	p.IS575fs	1
ROCK1	READ	chr18	18629822	18629822	T	G	Missense_Mutation	p.K65N	1
ROCK1	CESC	chr18	18588092	18588092	G	T	Missense_Mutation		1
ROCK1	HNSC	chr18	18566941	18566941	C	G	Missense_Mutation		1
ROCK1	STAD	chr18	18622574	18622574	C	A	Nonsense_Mutation	p.E258*	1
ROCK1	HNSC	chr18	18629092	18629092	C	A	Missense_Mutation	p.R125S	1
ROCK1	LIHC	chr18	18534973	18534973	T	-	Frame_Shift_Del	p.K1208fs	1
ROCK1	LUSC	chr18	18571141	18571141	C	T	Missense_Mutation	p.M713I	1
ROCK1	LUAD	chr18	18690844	18690844	G	A	Nonsense_Mutation	p.R10*	1
ROCK1	SKCM	chr18	18595437	18595437	G	A	Silent	p.T455T	1
ROCK1	BLCA	chr18	18625257	18625257	G	A	Missense_Mutation		1
ROCK1	HNSC	chr18	18572799	18572799	G	A	Missense_Mutation		1
ROCK1	THCA	chr18	18622160	18622160	G	A	Missense_Mutation		1
ROCK1	KIRC	chr18	18586509	18586515	CTTACAG	-	Frame_Shift_Del	p.561_563del	1
ROCK1	UVM	chr18	18534948	18534948	G	C	Missense_Mutation		1
ROCK1	COAD	chr18	18603599	18603599	G	A	Silent	p.S418S	1
ROCK1	STAD	chr18	18562783	18562783	C	A	Nonsense_Mutation	p.G834X	1
ROCK1	HNSC	chr18	18608856	18608856	A	G	Silent	p.D364D	1
ROCK1	LGG	chr18	18550345	18550345	T	C	Silent		1
ROCK1	READ	chr18	18650519	18650519	T	G	Missense_Mutation	p.K50T	1
ROCK1	PAAD	chr18	18622107	18622107	C	T	Missense_Mutation		1
ROCK1	SKCM	chr18	18586524	18586524	G	T	Nonsense_Mutation	p.S558X	1
ROCK1	CESC	chr18	18534772	18534772	C	T	Silent		1
ROCK1	HNSC	chr18	18586476	18586476	G	A	Missense_Mutation		1
ROCK1	STAD	chr18	18629740	18629740	C	T	Splice_Site	p.L92_splice	1
ROCK1	LIHC	chr18	18548767	18548767	T	-	Frame_Shift_Del	p.K990fs	1
ROCK1	LUSC	chr18	18588119	18588119	G	C	Missense_Mutation	p.Q483E	1
ROCK1	LUAD	chr18	18548810	18548810	C	A	Nonsense_Mutation	p.E976*	1
ROCK1	PRAD	chr18	18690838	18690839	-	AAA	In_Frame_Ins	p.E12delinsFE	1
ROCK1	SKCM	chr18	18595438	18595438	G	A	Missense_Mutation	p.T455I	1
ROCK1	BLCA	chr18	18690816	18690816	C	A	Missense_Mutation		1
ROCK1	HNSC	chr18	18629142	18629142	T	C	Missense_Mutation		1
ROCK1	KIRC	chr18	18535179	18535179	G	A	Silent	p.T1180T	1
ROCK1	BLCA	chr18	18690843	18690843	C	T	Missense_Mutation	p.R10Q	1
ROCK1	COAD	chr18	18619493	18619493	C	A	Nonsense_Mutation	p.E331X	1
ROCK1	LIHC	chr18	18625364	18625364	T	C	Missense_Mutation	p.D160G	1
ROCK1	LUAD	chr18	18622538	18622538	C	T	Missense_Mutation	p.E270K	1
ROCK1	READ	chr18	18547733	18547733	C	A	Nonsense_Mutation	p.E1058X	1
ROCK1	STAD	chr18	18629775	18629775	A	G	Missense_Mutation	p.V81A	1
ROCK1	PAAD	chr18	18547802	18547802	G	T	Silent		1
ROCK1	HNSC	chr18	18624129	18624135	GTTATCA	-	Frame_Shift_Del		1
ROCK1	STAD	chr18	18622646	18622646	C	T	Missense_Mutation	p.A234T	1
ROCK1	LIHC	chr18	18588068	18588068	T	-	Frame_Shift_Del	p.R500fs	1
ROCK1	LIHC	chr18	18549103	18549103	T	C	Missense_Mutation		1
ROCK1	LUAD	chr18	18622600	18622600	T	C	Missense_Mutation	p.Q249R	1
ROCK1	PRAD	chr18	18562759	18562759	G	A	Silent	p.L842L	1
ROCK1	SKCM	chr18	18539836	18539836	C	T	Silent	p.K1159K	1
ROCK1	BLCA	chr18	18533624	18533624	G	T	Missense_Mutation		1
ROCK1	CHOL	chr18	18608854	18608854	G	C	Missense_Mutation	p.T365S	1
ROCK1	THYM	chr18	18624063	18624063	C	T	Silent		1
ROCK1	LIHC	chr18	18559965	18559965	T	C	Missense_Mutation	p.T854A	1
ROCK1	LUAD	chr18	18547804	18547804	T	A	Missense_Mutation	p.N1034I	1
ROCK1	READ	chr18	18550412	18550412	C	T	Missense_Mutation	p.R906Q	1

Copy number variation (CNV) of ROCK1
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across ROCK1
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
89556	LUSC	TCGA-56-A49D	GNE	chr9	36236828	-	ROCK1	chr18	18650574	-
89556	LUSC	TCGA-56-A49D-01A	GNE	chr9	36236829	-	ROCK1	chr18	18650574	-
89556	N/A	EC569876	HDLBP	chr2	242198387	+	ROCK1	chr18	18679019	+
89556	N/A	BG029653	MYBL2	chr20	42345123	+	ROCK1	chr18	18532419	+
101205	BRCA	TCGA-C8-A12P-01A	ROCK1	chr18	18690779	-	ABHD3	chr18	19282459	-
101205	BRCA	TCGA-C8-A12P-01A	ROCK1	chr18	18690779	-	ABHD3	chr18	19283708	-
101205	LUSC	TCGA-85-8048-01A	ROCK1	chr18	18690779	-	ABHD3	chr18	19244191	-
80630	PAAD	TCGA-IB-A7M4-01A	ROCK1	chr18	18595392	-	ANKRD29	chr18	21181273	-
80630	STAD	TCGA-BR-8677-01A	ROCK1	chr18	18690779	-	ANKRD29	chr18	21229157	-
80898	HNSC	TCGA-CV-6953	ROCK1	chr18	18690778	-	B4GALT6	chr18	29246335	-
80898	HNSC	TCGA-CV-6953-01A	ROCK1	chr18	18690779	-	B4GALT6	chr18	29246335	-
86721	LUAD	TCGA-97-7552	ROCK1	chr18	18690778	-	CABYR	chr18	21735664	+
86721	LUAD	TCGA-97-7552-01A	ROCK1	chr18	18690779	-	CABYR	chr18	21735665	+
75318	LUSC	TCGA-63-A5MT-01A	ROCK1	chr18	18619433	-	CAMK2B	chr7	44323824	-
94619	LUSC	TCGA-LA-A7SW	ROCK1	chr18	18571136	-	CDH2	chr18	25532323	-
94619	LUSC	TCGA-LA-A7SW-01A	ROCK1	chr18	18571137	-	CDH2	chr18	25532323	-
100068	ESCA	TCGA-LN-A4MQ	ROCK1	chr18	18600111	-	CHD2	chr15	93510554	+
92428	PAAD	TCGA-2J-AAB4-01A	ROCK1	chr18	18539801	-	CHST9	chr18	24722869	-
102359	ESCA	TCGA-L5-A8NE-01A	ROCK1	chr18	18691436	-	CIDEA	chr18	12262824	+
101903	HNSC	TCGA-CV-5434	ROCK1	chr18	18586311	-	DCC	chr18	50912412	+
101903	HNSC	TCGA-CV-5434-01A	ROCK1	chr18	18586312	-	DCC	chr18	50912413	+
96562	OV	TCGA-13-0905	ROCK1	chr18	18690778	-	DHX9	chr1	182847155	+
75318	BLCA	TCGA-4Z-AA84-01A	ROCK1	chr18	18690779	-	FABP2	chr4	120241997	-
97138	LUAD	TCGA-44-A47G-01A	ROCK1	chr18	18690779	-	GATA6	chr18	19780619	+
92122	BLCA	TCGA-BT-A3PK-01A	ROCK1	chr18	18603581	-	GUCA2B	chr1	42620351	+
100826	STAD	TCGA-CG-4301-01A	ROCK1	chr18	18546878	-	LAMA3	chr18	21393021	+
75318	SARC	TCGA-QQ-A5V9	ROCK1	chr18	18619432	-	LAMP5	chr20	9510288	+
75318	SARC	TCGA-QQ-A5V9-01A	ROCK1	chr18	18619433	-	LAMP5	chr20	9510289	+
102519	BRCA	TCGA-A8-A091-01A	ROCK1	chr18	18625253	-	LRIG3	chr12	59308117	-
91371	SKCM	TCGA-YD-A9TA-06A	ROCK1	chr18	18546878	-	MAP1B	chr5	71479570	+
96716	PAAD	TCGA-XN-A8T3-01A	ROCK1	chr18	18603581	-	OSBPL1A	chr18	21883682	-
86307	STAD	TCGA-HU-A4GN-01A	ROCK1	chr18	18619433	-	PDE8A	chr15	85652284	+
94387	PRAD	TCGA-KK-A6E6-01A	ROCK1	chr18	18650493	-	RBM47	chr4	40546523	-
103108	LUSC	TCGA-56-A49D-01A	ROCK1	chr18	18690779	-	RNF38	chr9	36376124	-
103108	LUSC	TCGA-56-A49D-01A	ROCK1	chr18	18690779	-	RNF38	chr9	36390613	-
84924	HNSC	TCGA-CR-7371-01A	ROCK1	chr18	18690779	-	RPL29	chr3	52029896	-
75318	PAAD	TCGA-XN-A8T5-01A	ROCK1	chr18	18690779	-	THNSL1	chr10	25310671	+
89571	STAD	TCGA-BR-7901-01A	TBL1XR1	chr3	176914909	-	ROCK1	chr18	18619524	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRP	ROCK1	0.00088056874629339	0.025
LGG	ROCK1	0.0285822032033189	0.77
MESO	ROCK1	0.0330906471047638	0.86
TGCT	ROCK1	0.0373822016565736	0.93

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
THCA	ROCK1	0.0308194055819311	0.89
KIRC	ROCK1	0.00188527413596579	0.06
LGG	ROCK1	0.000342803715269553	0.011
BRCA	ROCK1	0.00932275038580322	0.29
UCS	ROCK1	0.0221091549953302	0.66

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Q13464	DB04707	Hydroxyfasudil	Inhibitor	Small molecule	Experimental
Q13464	DB07876	(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE		Small molecule	Experimental
Q13464	DB04707	Hydroxyfasudil	Inhibitor
Q13464	DB07876	(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source