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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS10 (NCBI Gene ID:6204)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS10
	Gene ID: 6204
	Gene Symbol	RPS10
	Gene ID	6204
	Gene Name	ribosomal protein S10
	Synonyms	DBA9\|S10
	Cytomap	6p21.31
	Type of Gene	protein-coding
	Description	40S ribosomal protein S10small ribosomal subunit protein eS10
	Modification date	20200313
	UniProtAcc	P46783

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPS10	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPS10[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS10	Cancer-Associated Eukaryotic Translation Initiation Factor 1A Mutants Impair Rps3 and Rps10 Binding and Enhance Scanning of Cell Cycle Genes	30420357

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
STAD	RPS10	1.24605170362267	0.00608485564589501
PRAD	RPS10	1.22440498374591	0.0436765184075403
LIHC	RPS10	-4.19375458193649	0.0467480881450754
KIRC	RPS10	-1.4011528971514	9.77063509146009e-07

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
LAML	RPS10	-0.022628728	0.003294005

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS10 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	RPS10	PFDN5	0.808097926	1.94E-11
CHOL	CGC	RPS10	NACA	0.835658394	9.26E-13
CHOL	TSG	RPS10	GLTSCR2	0.823473696	3.79E-12
CHOL	TSG	RPS10	GNB2L1	0.849737777	1.57E-13
DLBC	Cell metabolism gene	RPS10	POLR2J	0.800392863	8.66E-12
DLBC	Cell metabolism gene	RPS10	LSM2	0.813617463	2.09E-12
DLBC	Cell metabolism gene	RPS10	PSMB3	0.81437925	1.91E-12
DLBC	Cell metabolism gene	RPS10	PTDSS2	0.820834363	9.14E-13
DLBC	Cell metabolism gene	RPS10	GEMIN7	0.830128666	2.98E-13
DLBC	Cell metabolism gene	RPS10	TIMM9	0.831427538	2.54E-13
DLBC	Cell metabolism gene	RPS10	POLR2F	0.834000125	1.84E-13
DLBC	Cell metabolism gene	RPS10	PFDN5	0.840346096	8.05E-14
DLBC	Cell metabolism gene	RPS10	TIMM13	0.849418014	2.32E-14
DLBC	Cell metabolism gene	RPS10	TOMM22	0.854665264	1.09E-14
DLBC	Cell metabolism gene	RPS10	SNRPD2	0.861950717	3.63E-15
DLBC	Cell metabolism gene	RPS10	NME2	0.870457989	9.24E-16
DLBC	Cell metabolism gene	RPS10	FAU	0.871258748	8.09E-16
DLBC	CGC	RPS10	NACA	0.807604018	4.04E-12
DLBC	Epifactor	RPS10	FBL	0.849823319	2.19E-14
DLBC	IUPHAR	RPS10	MFSD2B	0.833399997	1.98E-13
DLBC	TF	RPS10	THAP4	0.808745901	3.57E-12
DLBC	TF	RPS10	NME2	0.870457989	9.24E-16
DLBC	TSG	RPS10	GLTSCR2	0.80367568	6.14E-12
DLBC	TSG	RPS10	GADD45GIP1	0.853226018	1.35E-14
DLBC	TSG	RPS10	GNB2L1	0.88957187	2.91E-17
GBM	Cell metabolism gene	RPS10	SSR2	0.811493776	1.63E-41
GBM	Cell metabolism gene	RPS10	SNRPG	0.815908435	2.65E-42
GBM	Cell metabolism gene	RPS10	SNRPD2	0.82151085	2.48E-43
GBM	Cell metabolism gene	RPS10	CCT4	0.823149032	1.22E-43
GBM	Cell metabolism gene	RPS10	LSM2	0.825887067	3.66E-44
GBM	Cell metabolism gene	RPS10	PFDN5	0.830509	4.59E-45
GBM	Cell metabolism gene	RPS10	ZNRD1	0.834675224	6.68E-46
GBM	Cell metabolism gene	RPS10	FAU	0.861452593	6.66E-52
KICH	TSG	RPS10	GAS5	0.810661929	2.12E-22
LGG	Cell metabolism gene	RPS10	LSM2	0.80578483	3.16E-122
LGG	Cell metabolism gene	RPS10	FAU	0.851329747	4.93E-150
LIHC	Cell metabolism gene	RPS10	ZNRD1	0.807702421	1.21E-98
LIHC	Cell metabolism gene	RPS10	LSM2	0.809127728	2.98E-99
PCPG	Epifactor	RPS10	FBL	0.800306515	5.84E-43
PCPG	TSG	RPS10	GNB2L1	0.824632975	1.19E-47
PRAD	Cell metabolism gene	RPS10	PFDN5	0.804274994	5.82E-126
PRAD	Cell metabolism gene	RPS10	ZNRD1	0.804408518	4.92E-126
PRAD	Cell metabolism gene	RPS10	POLR2F	0.812989355	8.19E-131
PRAD	Cell metabolism gene	RPS10	POLR2I	0.815495096	2.96E-132
PRAD	Cell metabolism gene	RPS10	TIMM13	0.819333867	1.65E-134
PRAD	Cell metabolism gene	RPS10	TIMM9	0.821945542	4.52E-136
PRAD	Cell metabolism gene	RPS10	NME2	0.834374468	7.03E-144
PRAD	Cell metabolism gene	RPS10	PSMB7	0.841069884	2.33E-148
PRAD	Cell metabolism gene	RPS10	TOMM7	0.847571299	6.50E-153
PRAD	Cell metabolism gene	RPS10	FAU	0.856399683	1.89E-159
PRAD	Cell metabolism gene	RPS10	SNRPD2	0.86535343	1.52E-166
PRAD	Epifactor	RPS10	FBL	0.867792051	1.45E-168
PRAD	TF	RPS10	ZNF524	0.80420643	6.34E-126
PRAD	TF	RPS10	NME2	0.834374468	7.03E-144
PRAD	TSG	RPS10	GAS5	0.808064647	4.85E-128
PRAD	TSG	RPS10	GNB2L1	0.843402004	5.72E-150
READ	Cell metabolism gene	RPS10	LSM2	0.857819758	1.53E-31
TGCT	Epifactor	RPS10	FBL	0.835685023	6.37E-42
THCA	Cell metabolism gene	RPS10	PFDN5	0.836676457	3.71E-151
THCA	Cell metabolism gene	RPS10	FAU	0.846717895	2.43E-158
THCA	Cell metabolism gene	RPS10	SNRPD2	0.856441614	8.28E-166
THCA	Epifactor	RPS10	FBL	0.848048931	2.48E-159
THCA	TSG	RPS10	GNB2L1	0.81774612	7.42E-139
THYM	Cell metabolism gene	RPS10	APRT	0.802336129	1.15E-28
THYM	Cell metabolism gene	RPS10	TOMM22	0.802832872	1.01E-28
THYM	Cell metabolism gene	RPS10	IMPDH2	0.803189835	9.12E-29
THYM	Cell metabolism gene	RPS10	EXOSC4	0.804555015	6.28E-29
THYM	Cell metabolism gene	RPS10	PSMB3	0.808173863	2.30E-29
THYM	Cell metabolism gene	RPS10	ACOT8	0.810579031	1.16E-29
THYM	Cell metabolism gene	RPS10	MVD	0.810737312	1.11E-29
THYM	Cell metabolism gene	RPS10	PSMB1	0.813024189	5.77E-30
THYM	Cell metabolism gene	RPS10	SMPD2	0.814818208	3.42E-30
THYM	Cell metabolism gene	RPS10	POLD2	0.815768652	2.59E-30
THYM	Cell metabolism gene	RPS10	DPM2	0.826491279	9.97E-32
THYM	Cell metabolism gene	RPS10	PSMD13	0.829004255	4.50E-32
THYM	Cell metabolism gene	RPS10	TALDO1	0.837612488	2.66E-33
THYM	Cell metabolism gene	RPS10	FPGS	0.839122487	1.59E-33
THYM	Cell metabolism gene	RPS10	PGLS	0.842107984	5.69E-34
THYM	Cell metabolism gene	RPS10	TIMM8B	0.842761729	4.53E-34
THYM	Cell metabolism gene	RPS10	PSMC3	0.843513114	3.48E-34
THYM	Cell metabolism gene	RPS10	PSMB7	0.845701322	1.60E-34
THYM	Cell metabolism gene	RPS10	PFDN5	0.854698214	5.77E-36
THYM	Cell metabolism gene	RPS10	TIMM13	0.871517469	6.06E-39
THYM	Cell metabolism gene	RPS10	SSR2	0.873933079	2.09E-39
THYM	Cell metabolism gene	RPS10	SLC27A5	0.875453873	1.06E-39
THYM	Cell metabolism gene	RPS10	LSM2	0.87652731	6.50E-40
THYM	Cell metabolism gene	RPS10	SNRPD2	0.878787122	2.30E-40
THYM	Cell metabolism gene	RPS10	FAU	0.889965355	9.78E-43
THYM	CGC	RPS10	RBM10	0.807372863	2.87E-29
THYM	CGC	RPS10	SDHAF2	0.837945002	2.38E-33
THYM	CGC	RPS10	TFPT	0.839807893	1.26E-33
THYM	Epifactor	RPS10	SIRT6	0.801281624	1.53E-28
THYM	Epifactor	RPS10	EXOSC4	0.804555015	6.28E-29
THYM	Epifactor	RPS10	RUVBL2	0.805255649	5.17E-29
THYM	Epifactor	RPS10	PPP4C	0.815147407	3.11E-30
THYM	Epifactor	RPS10	DMAP1	0.816898274	1.86E-30
THYM	Epifactor	RPS10	CXXC1	0.818172916	1.27E-30
THYM	Epifactor	RPS10	RRP8	0.821881465	4.16E-31
THYM	Epifactor	RPS10	TAF10	0.831058846	2.33E-32
THYM	Epifactor	RPS10	PRPF31	0.832843968	1.30E-32
THYM	Epifactor	RPS10	TFPT	0.839807893	1.26E-33
THYM	Epifactor	RPS10	NOC2L	0.84146174	7.12E-34
THYM	Epifactor	RPS10	MBD3	0.844881098	2.14E-34
THYM	Epifactor	RPS10	BRMS1	0.846004256	1.44E-34
THYM	Epifactor	RPS10	C17orf49	0.847799523	7.52E-35
THYM	Epifactor	RPS10	FBL	0.91996142	1.24E-50
THYM	IUPHAR	RPS10	SIRT6	0.801281624	1.53E-28
THYM	IUPHAR	RPS10	IMPDH2	0.803189835	9.12E-29
THYM	IUPHAR	RPS10	MVD	0.810737312	1.11E-29
THYM	IUPHAR	RPS10	PSMB1	0.813024189	5.77E-30
THYM	IUPHAR	RPS10	SMPD2	0.814818208	3.42E-30
THYM	IUPHAR	RPS10	EGLN2	0.823073579	2.88E-31
THYM	IUPHAR	RPS10	MFSD2B	0.825153754	1.52E-31
THYM	IUPHAR	RPS10	SLC27A5	0.875453873	1.06E-39
THYM	TF	RPS10	CXXC1	0.818172916	1.27E-30
THYM	TF	RPS10	ZNF428	0.818347827	1.21E-30
THYM	TF	RPS10	THAP3	0.820601547	6.13E-31
THYM	TF	RPS10	ZNF581	0.826459066	1.01E-31
THYM	TF	RPS10	REXO4	0.827166622	8.06E-32
THYM	TF	RPS10	MBD3	0.844881098	2.14E-34
THYM	TSG	RPS10	SIRT6	0.801281624	1.53E-28
THYM	TSG	RPS10	BRMS1	0.846004256	1.44E-34
THYM	TSG	RPS10	TSSC4	0.86597351	6.43E-38
THYM	TSG	RPS10	GLTSCR2	0.871226502	6.88E-39
THYM	TSG	RPS10	GNB2L1	0.89446324	9.17E-44
UCS	Cell metabolism gene	RPS10	APRT	0.802336129	1.15E-28
UCS	Cell metabolism gene	RPS10	TOMM22	0.802832872	1.01E-28
UCS	Cell metabolism gene	RPS10	IMPDH2	0.803189835	9.12E-29
UCS	Cell metabolism gene	RPS10	EXOSC4	0.804555015	6.28E-29
UCS	Cell metabolism gene	RPS10	PSMB3	0.808173863	2.30E-29
UCS	Cell metabolism gene	RPS10	ACOT8	0.810579031	1.16E-29
UCS	Cell metabolism gene	RPS10	MVD	0.810737312	1.11E-29
UCS	Cell metabolism gene	RPS10	PSMB1	0.813024189	5.77E-30
UCS	Cell metabolism gene	RPS10	SMPD2	0.814818208	3.42E-30
UCS	Cell metabolism gene	RPS10	POLD2	0.815768652	2.59E-30
UCS	Cell metabolism gene	RPS10	DPM2	0.826491279	9.97E-32
UCS	Cell metabolism gene	RPS10	PSMD13	0.829004255	4.50E-32
UCS	Cell metabolism gene	RPS10	TALDO1	0.837612488	2.66E-33
UCS	Cell metabolism gene	RPS10	FPGS	0.839122487	1.59E-33
UCS	Cell metabolism gene	RPS10	PGLS	0.842107984	5.69E-34
UCS	Cell metabolism gene	RPS10	TIMM8B	0.842761729	4.53E-34
UCS	Cell metabolism gene	RPS10	PSMC3	0.843513114	3.48E-34
UCS	Cell metabolism gene	RPS10	PSMB7	0.845701322	1.60E-34
UCS	Cell metabolism gene	RPS10	PFDN5	0.854698214	5.77E-36
UCS	Cell metabolism gene	RPS10	TIMM13	0.871517469	6.06E-39
UCS	Cell metabolism gene	RPS10	SSR2	0.873933079	2.09E-39
UCS	Cell metabolism gene	RPS10	SLC27A5	0.875453873	1.06E-39
UCS	Cell metabolism gene	RPS10	LSM2	0.87652731	6.50E-40
UCS	Cell metabolism gene	RPS10	SNRPD2	0.878787122	2.30E-40
UCS	Cell metabolism gene	RPS10	FAU	0.889965355	9.78E-43
UCS	CGC	RPS10	RBM10	0.807372863	2.87E-29
UCS	CGC	RPS10	SDHAF2	0.837945002	2.38E-33
UCS	CGC	RPS10	TFPT	0.839807893	1.26E-33
UCS	Epifactor	RPS10	SIRT6	0.801281624	1.53E-28
UCS	Epifactor	RPS10	EXOSC4	0.804555015	6.28E-29
UCS	Epifactor	RPS10	RUVBL2	0.805255649	5.17E-29
UCS	Epifactor	RPS10	PPP4C	0.815147407	3.11E-30
UCS	Epifactor	RPS10	DMAP1	0.816898274	1.86E-30
UCS	Epifactor	RPS10	CXXC1	0.818172916	1.27E-30
UCS	Epifactor	RPS10	RRP8	0.821881465	4.16E-31
UCS	Epifactor	RPS10	TAF10	0.831058846	2.33E-32
UCS	Epifactor	RPS10	PRPF31	0.832843968	1.30E-32
UCS	Epifactor	RPS10	TFPT	0.839807893	1.26E-33
UCS	Epifactor	RPS10	NOC2L	0.84146174	7.12E-34
UCS	Epifactor	RPS10	MBD3	0.844881098	2.14E-34
UCS	Epifactor	RPS10	BRMS1	0.846004256	1.44E-34
UCS	Epifactor	RPS10	C17orf49	0.847799523	7.52E-35
UCS	Epifactor	RPS10	FBL	0.91996142	1.24E-50
UCS	IUPHAR	RPS10	SIRT6	0.801281624	1.53E-28
UCS	IUPHAR	RPS10	IMPDH2	0.803189835	9.12E-29
UCS	IUPHAR	RPS10	MVD	0.810737312	1.11E-29
UCS	IUPHAR	RPS10	PSMB1	0.813024189	5.77E-30
UCS	IUPHAR	RPS10	SMPD2	0.814818208	3.42E-30
UCS	IUPHAR	RPS10	EGLN2	0.823073579	2.88E-31
UCS	IUPHAR	RPS10	MFSD2B	0.825153754	1.52E-31
UCS	IUPHAR	RPS10	SLC27A5	0.875453873	1.06E-39
UCS	TF	RPS10	CXXC1	0.818172916	1.27E-30
UCS	TF	RPS10	ZNF428	0.818347827	1.21E-30
UCS	TF	RPS10	THAP3	0.820601547	6.13E-31
UCS	TF	RPS10	ZNF581	0.826459066	1.01E-31
UCS	TF	RPS10	REXO4	0.827166622	8.06E-32
UCS	TF	RPS10	MBD3	0.844881098	2.14E-34
UCS	TSG	RPS10	SIRT6	0.801281624	1.53E-28
UCS	TSG	RPS10	BRMS1	0.846004256	1.44E-34
UCS	TSG	RPS10	TSSC4	0.86597351	6.43E-38
UCS	TSG	RPS10	GLTSCR2	0.871226502	6.88E-39
UCS	TSG	RPS10	GNB2L1	0.89446324	9.17E-44
UVM	Cell metabolism gene	RPS10	GMDS	0.816142209	2.90E-20

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPS10	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPS10	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPS10	RPS16	-1.35957043617517	0.00019507110118866
STAD	RPS10	RPS23	1.85076760664576	0.000364991836249828
COAD	RPS10	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPS10	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPS10	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPS10	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPS10	RPL19	1.36901182894089	0.00250792503356934
KICH	RPS10	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPS10	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPS10	RPS16	-6.16322798156577	0.0115764821363307
LUSC	RPS10	RPS23	1.46751169891047	0.0174932185880974
BLCA	RPS10	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPS10	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPS10	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPS10	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPS10	RPL19	-2.14669889516666	0.044366810398747
UCEC	RPS10	RPS23	-2.03658159814007	0.046875
KIRC	RPS10	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPS10	RPS12	-4.91239327478244	1.85340619742495e-09
KIRC	RPS10	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPS10	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPS10	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPS10	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPS10	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRP	RPS10	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPS10	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPS10	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS10

PINX1, HAP1, HIP1, KAT7, PFN2, PTTG1, H2AFX, CD4, DCC, MME, WIZ, DVL3, TCF25, EED, XRCC6, DNMT3B, DMPK, RAD21, SIRT7, SYK, TP53, CUL3, CUL5, CDK2, CUL1, COPS5, DCUN1D1, CAND1, NEDD8, PIK3R2, RPS4X, APP, RPL10, RPL27, RPL31, RPL9, RPS13, RPS15A, RPS3, RPS24, RPS14, RPS26, RPS2, RPSA, RPS7, RPS16, RPL14, RPS25, RPS11, RPLP1, RPS19, RPS8, RPL5, RPLP0, RPS3A, RPL11, RPS27A, RPS29, MOV10, RPLP0P6, RPL10L, PRPF3, PRPF4, UQCRB, PRPF19, TMCO1, ATP5O, SMURF1, FN1, VCAM1, UBL4A, ITGA4, PAN2, RAD52, FBXO25, FBXO6, EIF3A, EIF3E, EIF3K, LARP1, EIF2A, RPL28, RPS15, RPS18, RPS20, RPS21, RPS28, RPS5, RPS9, RPS12, RPS17, RPS23, RPS27, RPS6, SERBP1, TSR1, WIBG, ASB10, AURKA, CEP250, TUBG1, TUBGCP3, HUWE1, CUL7, RNF2, FBXW11, NRDE2, RPL10A, RPL12, RPL13, RPL13A, RPL15, RPL23, RPL27A, RPL3, RPL30, RPL35, RPL36, RPL37A, RPL38, RPL4, RPL7, RPL7A, RPL8, RPLP2, BCAS2, RAP2C, RPL18, RPL18A, RPL19, RPL21, RPL22, RPL23A, RPL24, RPL35A, RPL6, TMED2, LOC101929876, RRP7A, TOMM22, BTRC, MED20, EWSR1, XPO1, HIST1H3E, AHSA1, CBR3, HNRNPU, NPM1, EXOSC4, CAMKK1, Eif3a, Eif3e, Rab5c, Rpl35, Srp72, GAN, TRIM29, MCM2, Ksr1, Mdm2, RC3H1, EIF2S2, CDC73, RRS1, HIST1H1E, HIST1H1A, HIST1H1T, CHEK2, CHEK1, NCL, CYLD, TRIM25, HEY1, ZNF598, WDR77, CTNNB1, TGFB1, PYHIN1, PRPF8, EFTUD2, AAR2, PIH1D1, NFKB1, RNF4, CHD3, CHD4, RNF31, TNF, RIOK1, HEXIM1, MEPCE, LARP7, RNF123, SNAI1, AGR2, RECQL4, DCPS, REST, ZFP36L2, MYC, CDK9, Prkaa1, Prkab1, KIAA1429, EIF4B, RC3H2, ACTC1, PHB, USP14, PPP1CC, VRK3, HIST1H4A, SNRNP70, ITFG1, HMGB1, BIRC3, NFX1, WWP2, TRIM28, LRRK2, CMTR1, ARIH2, PLEKHA4, YAP1, TFCP2, FANCD2, HCVgp1, ZC3H18, BCAP31, LARS, MAP7D3, nsp1, ORF8, TOP3B, USP10, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, FASN, LRRC59, BRD4, RBM45, Apc2, RBM39, FBP1, MKRN1, N, DNAJB1, DNAJC2, SEC63, BAG5, SPOP, PARK2, UFL1, DDRGK1, ATG10, UBQLN1, FZR1, WDR5, LIN28B, HIST1H1C, YBX2, THAP3, ZC3H8, SSB, RPS26P11, RSL1D1, GNL2, YBX1, ZNF629, ABT1, ZBTB24, ZFR, H2AFB3, NGDN, RSBN1L, DDX55, SREK1, SRSF5, FAM120A, ZCRB1, GLE1, RSBN1, SURF6, ZNF184, HIST1H2AM, CLTCL1, PURA, ZNF354A, CHCHD4, GLYR1, NSA2, DHX57, NOL10, ZNF70, BAZ1B, NIFK, ZNF668, SRSF6, PRR3, ZNF771, DDX27, POP1, SRSF12, ZNF646, ZNF384, YBX3, DDX21, ZNF777, KRI1, H2AFB2, LIN28A, RPL26L1, RPF1, HP1BP3, H1FX, DDX10, ZSCAN25, ZC3HAV1, FARS2, CTCF, DKC1, PURB, SRSF1, REXO4, RBM19, ZNF358, MAGEB2, NAT10, PRDM15, ZNF768, SCAF1, TOE1, RPL36AL, AATF, GLI4, SF3B2, ADARB1, MRPL2, SF3B1, ZNF574, SRSF4, H1FNT, ZBTB11, ZNF48, ZNF800, BMS1, CCDC86, HIST1H1B, HIST1H1D, MCEE, PRDM10, KRR1, ZNF346, DDX50, HERC5, DHX36, DDX31, NKRF, OASL, RTCA, HIST2H2AB, RPL17, SRPK2, HELZ2, DDX18, GLTSCR2, FGFBP1, UTP23, CCDC137, CCDC59, EPB41L4B, IMP4, WHSC1, YTHDC2, GTPBP4, METTL17, MAP7D1, ASCC3, RBM17, GAR1, CUEDC1, FAM111A, NOM1, HIST2H2AC, DDX54, SPATS2, ZNF22, DHX30, ASCC2, CHERP, RBM14-RBM4, U2SURP, UTP3, RPS4Y2, KNOP1, PRKRIR, NOP16, TRIP4, RPSAP58, CBX6, DHX37, APOBEC3D, DDX24, RIOK3, SNRPA1, LTV1, HIST1H2AE, TTF1, RRP15, STAU1, PPAN-P2RY11, SPATS2L, STAU2, ZNF121, ZFP91, RPL7L1, SDAD1, ZNF770, YTHDF1, ZCCHC6, PURG, NOL12, DDX56, FAM111B, LUC7L, LARP1B, MPHOSPH10, RSL24D1, PAK1IP1, ZNF512, IMP3, H2AFY, CDC5L, EPB41L5, MYBBP1A, RRP12, SPRTN, BTF3, FBXW7, E, ORF7b, S, nsp4, ORF10, ORF6, RCHY1, SLFN11, nsp14, CPEB1, KLF15, KLF16, KLF4, KLF8, SP1, TLX1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RPS10	chr6	34385135	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34385240	T	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant
RPS10	chr6	34385258	C	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001624\|3_prime_UTR_variant,SO:0001627\|intron_variant
RPS10	chr6	34385330	A	G	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34385498	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34385517	A	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34385919	G	GT	Duplication	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34386139	TACTC	T	Deletion	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
RPS10	chr6	34386165	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34386170	A	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34386194	G	A	single_nucleotide_variant	Benign/Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34386194	G	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34386203	T	C	single_nucleotide_variant	Likely_pathogenic	Diamond-Blackfan_anemia	SO:0001574\|splice_acceptor_variant	SO:0001574\|splice_acceptor_variant
RPS10	chr6	34386210	T	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34386219	G	A	single_nucleotide_variant	Benign	not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34386403	A	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389213	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389214	AC	A	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389217	C	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389219	C	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389224	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389360	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389507	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34389543	C	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34389570	G	A	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_9	SO:0001587\|nonsense	SO:0001587\|nonsense
RPS10	chr6	34389689	CT	C	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389796	G	GA	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389796	GA	G	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389796	GAA	G	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34389796	GAAA	G	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392137	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392160	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392441	C	CATA	Duplication	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
RPS10	chr6	34392453	C	CCGAGGCCTGCCAGTCTCTGGA	Duplication	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001821\|inframe_insertion	SO:0001821\|inframe_insertion
RPS10	chr6	34392471	T	C	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392475	CGGCTACGG	C	Deletion	Pathogenic	Diamond-Blackfan_anemia	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
RPS10	chr6	34392507	C	CG	Duplication	Pathogenic	Diamond-Blackfan_anemia_9	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
RPS10	chr6	34392507	C	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392537	C	T	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392546	C	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392564	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392567	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392582	A	G	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392600	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392653	A	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392839	AC	A	Deletion	Likely_benign	Diamond-Blackfan_anemia	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392840	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34392864	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392888	G	C	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34392896	G	A	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392910	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34392928	T	C	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34392959	G	A	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RPS10	chr6	34392993	C	T	single_nucleotide_variant	Benign/Likely_benign	Diamond-Blackfan_anemia\|Diamond-Blackfan_anemia_9	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS10	chr6	34392996	C	T	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_9	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant
RPS10	chr6	34392998	T	C	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant
RPS10	chr6	34393001	G	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34393016	T	C	single_nucleotide_variant	Likely_benign	not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34393212	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34393276	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS10	chr6	34393591	T	G	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia	SO:0001623\|5_prime_UTR_variant,SO:0001627\|intron_variant	SO:0001623\|5_prime_UTR_variant,SO:0001627\|intron_variant
RPS10	chr6	34393817	C	G	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393822	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393829	G	C	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393835	G	T	single_nucleotide_variant	Uncertain_significance	Diamond-Blackfan_anemia_9	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393837	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393839	TG	T	Deletion	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393844	AGG	A	Deletion	Uncertain_significance	Diamond-Blackfan_anemia	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393845	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia_9\|not_specified	SO:0001623\|5_prime_UTR_variant	SO:0001623\|5_prime_UTR_variant
RPS10	chr6	34393851	A	C	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia
RPS10	chr6	34393855	T	C	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia
RPS10	chr6	34393866	G	A	single_nucleotide_variant	Benign	Diamond-Blackfan_anemia
RPS10	chr6	34393906	A	G	single_nucleotide_variant	Likely_benign	Diamond-Blackfan_anemia

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPS10	CHOL	chr6	34392484	34392484	C	G	Missense_Mutation	p.R95P	4
RPS10	BRCA	chr6	34389559	34389559	T	A	Missense_Mutation	p.R116S	3
RPS10	ESCA	chr6	34389563	34389563	G	A	Missense_Mutation		2
RPS10	CESC	chr6	34386188	34386188	C	G	Missense_Mutation		2
RPS10	LAML	chr6	34500485	34500485	C	T	Silent	p.P87	2
RPS10	UCEC	chr6	34392483	34392483	G	A	Silent	p.R95	2
RPS10	UCEC	chr6	34392973	34392973	A	G	Missense_Mutation	p.I9T	2
RPS10	LIHC	chr6	34389539	34389539	T	C	Missense_Mutation		2
RPS10	ESCA	chr6	34389563	34389563	G	A	Missense_Mutation	p.A115V	2
RPS10	ESCA	chr6	34393814	34393814	C	T	RNA	NULL	1
RPS10	LIHC	chr6	34385629	34385629	T	-	Frame_Shift_Del	p.R168fs	1
RPS10	LUAD	chr6	34385290	34385290	G	T	Missense_Mutation	p.P164H	1
RPS10	GBM	chr6	34392454	34392454	C	T	Missense_Mutation		1
RPS10	OV	chr6	34500851	34500851	G	T	Missense_Mutation	p.N42K	1
RPS10	HNSC	chr6	34392616	34392616	G	A	Missense_Mutation		1
RPS10	OV	chr6	34500977	34500977	C	A	Splice_Site	e1-1	1
RPS10	BLCA	chr6	34392899	34392899	C	G	Missense_Mutation		1
RPS10	HNSC	chr6	34392463	34392463	C	T	Missense_Mutation	p.G102D	1
RPS10	READ	chr6	34389567	34389567	G	A	Missense_Mutation	p.P114S	1
RPS10	KIRP	chr6	34392605	34392605	G	T	Missense_Mutation		1
RPS10	SARC	chr6	34386177	34386177	G	T	Missense_Mutation		1
RPS10	KIRP	chr6	34385288	34385288	G	T	Missense_Mutation		1
RPS10	SARC	chr6	34392477	34392477	G	T	Missense_Mutation		1
RPS10	CESC	chr6	34386188	34386188	C	G	Missense_Mutation	p.K138N	1
RPS10	LGG	chr6	34392602	34392602	C	A	Missense_Mutation		1
RPS10	COAD	chr6	34392484	34392484	C	T	Missense_Mutation	p.R95H	1
RPS10	LIHC	chr6	34389539	34389539	T	C	Missense_Mutation	p.D123G	1

Copy number variation (CNV) of RPS10
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS10
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
58300	Non-Cancer	61N	NDUFV3	chr21	44317157	+	RPS10	chr6	34389584	-
84446	UCEC	TCGA-5B-A90C	RPS10	chr6	34392446	-	CUEDC1	chr17	55963240	-
77291	HNSC	TCGA-P3-A6SX-01A	RPS10	chr6	34392446	-	ITPR3	chr6	33623543	+
102786	STAD	TCGA-D7-5577-01A	RPS10	chr6	34392446	-	PKM	chr15	72492996	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPS10	0.0082408394692588	0.23
BRCA	RPS10	0.0197944894259278	0.53
MESO	RPS10	0.0223498777540424	0.58

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	RPS10	0.0146231532630724	0.45
LGG	RPS10	0.00286875574368733	0.095
BRCA	RPS10	0.00356905183634806	0.11
PAAD	RPS10	0.0376291865338243	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C2750081	Diamond-Blackfan Anemia 9	6	CLINGEN;CTD_human;GENOMICS_ENGLAND
C1260899	Anemia, Diamond-Blackfan	4	GENOMICS_ENGLAND
C2931850	Aase Smith syndrome 2	1	GENOMICS_ENGLAND