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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS15A (NCBI Gene ID:6210)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS15A
	Gene ID: 6210
	Gene Symbol	RPS15A
	Gene ID	6210
	Gene Name	ribosomal protein S15a
	Synonyms	DBA20\|S15a
	Cytomap	16p12.3
	Type of Gene	protein-coding
	Description	40S ribosomal protein S15asmall ribosomal subunit protein uS8up-regulated by HBV X protein
	Modification date	20200313
	UniProtAcc	P62244

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	RPS15A	GO:0008284	positive regulation of cell proliferation	15108328
Hgene	RPS15A	GO:0009615	response to virus	15108328
Hgene	RPS15A	GO:0045787	positive regulation of cell cycle	15108328

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPS15A	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPS15A[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS15A	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000322989	18799384	18799464	Frame-shift
ENST00000563390	18799384	18799464	Frame-shift
ENST00000565420	18799384	18799464	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
BRCA	RPS15A	-1.39403174309699	0.000110797167056844
STAD	RPS15A	1.10140997786082	0.0148032568395138
BLCA	RPS15A	-3.67919690742966	0.0445594787597656
KIRC	RPS15A	-4.14252623992016	2.15831756070263e-10
KIRP	RPS15A	-1.51145101417385	4.02145087718964e-06

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type	Gene	miRNA	TargetScan binding score (Context++ score percentile)	Coefficient	Pvalue
READ	RPS15A	hsa-miR-186-5p	73	-0.30968841285297	0.00566088307863855

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
ESCA	RPS15A	-0.09317384	0.009710429
MESO	RPS15A	0.063878915	0.042422633

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS15A (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	RPS15A	TBCA	0.802620051	6.86E-12
DLBC	Cell metabolism gene	RPS15A	DGUOK	0.805064408	5.30E-12
DLBC	Cell metabolism gene	RPS15A	POLR2F	0.812687061	2.31E-12
DLBC	Cell metabolism gene	RPS15A	PGLS	0.8147555	1.84E-12
DLBC	Cell metabolism gene	RPS15A	GFER	0.817373302	1.36E-12
DLBC	Cell metabolism gene	RPS15A	TIMM9	0.822874274	7.19E-13
DLBC	Cell metabolism gene	RPS15A	TOMM22	0.833042818	2.07E-13
DLBC	Cell metabolism gene	RPS15A	NME2	0.846822353	3.34E-14
DLBC	Cell metabolism gene	RPS15A	PFDN5	0.856303901	8.56E-15
DLBC	Cell metabolism gene	RPS15A	FAU	0.872304146	6.78E-16
DLBC	Cell metabolism gene	RPS15A	SNRPD2	0.892392788	1.66E-17
DLBC	CGC	RPS15A	NACA	0.885462769	6.44E-17
DLBC	Epifactor	RPS15A	FBL	0.827124568	4.32E-13
DLBC	TF	RPS15A	NME2	0.846822353	3.34E-14
DLBC	TSG	RPS15A	HINT1	0.806405781	4.59E-12
DLBC	TSG	RPS15A	GADD45GIP1	0.833370073	1.99E-13
DLBC	TSG	RPS15A	GNB2L1	0.914738932	1.00E-19
GBM	Cell metabolism gene	RPS15A	LSM1	0.804099938	3.05E-40
GBM	Cell metabolism gene	RPS15A	PFDN5	0.809654007	3.41E-41
GBM	Cell metabolism gene	RPS15A	SSR4	0.812192538	1.22E-41
GBM	Cell metabolism gene	RPS15A	ZNRD1	0.813683144	6.66E-42
GBM	Cell metabolism gene	RPS15A	SNRPD2	0.814517738	4.72E-42
GBM	Cell metabolism gene	RPS15A	PIGC	0.815321965	3.39E-42
GBM	Cell metabolism gene	RPS15A	FAU	0.816954148	1.72E-42
GBM	Cell metabolism gene	RPS15A	PSMA5	0.817546602	1.34E-42
GBM	Cell metabolism gene	RPS15A	SNRPG	0.839777954	5.85E-47
GBM	Cell metabolism gene	RPS15A	SSR2	0.851576353	1.49E-49
GBM	TSG	RPS15A	GAS5	0.827016443	2.22E-44
HNSC	Cell metabolism gene	RPS15A	PFDN5	0.802332495	1.66E-128
LGG	Cell metabolism gene	RPS15A	FAU	0.852668628	5.47E-151
LGG	CGC	RPS15A	NACA	0.82849593	4.60E-135
LGG	TSG	RPS15A	GAS5	0.816160203	7.19E-128
LGG	TSG	RPS15A	GNB2L1	0.879087355	4.91E-172
PRAD	Cell metabolism gene	RPS15A	TIMM9	0.802265704	7.05E-125
PRAD	CGC	RPS15A	NACA	0.827329922	2.24E-139
PRAD	Epifactor	RPS15A	FBL	0.812941114	8.73E-131
PRAD	TSG	RPS15A	GNB2L1	0.807497135	1.00E-127
THYM	Cell metabolism gene	RPS15A	PSMB7	0.811040877	1.02E-29
THYM	Cell metabolism gene	RPS15A	PGLS	0.812373551	6.96E-30
THYM	Cell metabolism gene	RPS15A	POLR2I	0.814609901	3.64E-30
THYM	Cell metabolism gene	RPS15A	TIMM8B	0.81626377	2.24E-30
THYM	Cell metabolism gene	RPS15A	TIMM13	0.817111566	1.74E-30
THYM	Cell metabolism gene	RPS15A	SSR2	0.822565249	3.37E-31
THYM	Cell metabolism gene	RPS15A	PFDN5	0.828503502	5.28E-32
THYM	Cell metabolism gene	RPS15A	SNRPD2	0.833763526	9.62E-33
THYM	Cell metabolism gene	RPS15A	APRT	0.835237449	5.90E-33
THYM	Cell metabolism gene	RPS15A	FAU	0.841693419	6.57E-34
THYM	Cell metabolism gene	RPS15A	DPM2	0.843964212	2.97E-34
THYM	Epifactor	RPS15A	ZNHIT1	0.800338663	1.97E-28
THYM	Epifactor	RPS15A	BRMS1	0.805225679	5.22E-29
THYM	Epifactor	RPS15A	TAF10	0.807401666	2.85E-29
THYM	Epifactor	RPS15A	PRPF31	0.820819265	5.74E-31
THYM	Epifactor	RPS15A	FBL	0.839530533	1.39E-33
THYM	TF	RPS15A	ZNF581	0.812438653	6.83E-30
THYM	TF	RPS15A	REXO4	0.817581521	1.52E-30
THYM	TSG	RPS15A	TSSC4	0.803932556	7.44E-29
THYM	TSG	RPS15A	BRMS1	0.805225679	5.22E-29
THYM	TSG	RPS15A	GNB2L1	0.819948831	7.47E-31
UCS	Cell metabolism gene	RPS15A	PSMB7	0.811040877	1.02E-29
UCS	Cell metabolism gene	RPS15A	PGLS	0.812373551	6.96E-30
UCS	Cell metabolism gene	RPS15A	POLR2I	0.814609901	3.64E-30
UCS	Cell metabolism gene	RPS15A	TIMM8B	0.81626377	2.24E-30
UCS	Cell metabolism gene	RPS15A	TIMM13	0.817111566	1.74E-30
UCS	Cell metabolism gene	RPS15A	SSR2	0.822565249	3.37E-31
UCS	Cell metabolism gene	RPS15A	PFDN5	0.828503502	5.28E-32
UCS	Cell metabolism gene	RPS15A	SNRPD2	0.833763526	9.62E-33
UCS	Cell metabolism gene	RPS15A	APRT	0.835237449	5.90E-33
UCS	Cell metabolism gene	RPS15A	FAU	0.841693419	6.57E-34
UCS	Cell metabolism gene	RPS15A	DPM2	0.843964212	2.97E-34
UCS	Epifactor	RPS15A	ZNHIT1	0.800338663	1.97E-28
UCS	Epifactor	RPS15A	BRMS1	0.805225679	5.22E-29
UCS	Epifactor	RPS15A	TAF10	0.807401666	2.85E-29
UCS	Epifactor	RPS15A	PRPF31	0.820819265	5.74E-31
UCS	Epifactor	RPS15A	FBL	0.839530533	1.39E-33
UCS	TF	RPS15A	ZNF581	0.812438653	6.83E-30
UCS	TF	RPS15A	REXO4	0.817581521	1.52E-30
UCS	TSG	RPS15A	TSSC4	0.803932556	7.44E-29
UCS	TSG	RPS15A	BRMS1	0.805225679	5.22E-29
UCS	TSG	RPS15A	GNB2L1	0.819948831	7.47E-31
UVM	Cell metabolism gene	RPS15A	TIMM9	0.812595203	5.68E-20
UVM	CGC	RPS15A	NACA	0.823020577	7.52E-21
UVM	TSG	RPS15A	GAS5	0.822322883	8.65E-21

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPS15A	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPS15A	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPS15A	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPS15A	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPS15A	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPS15A	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPS15A	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPS15A	RPL19	1.36901182894089	0.00250792503356934
KICH	RPS15A	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPS15A	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPS15A	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPS15A	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPS15A	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPS15A	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPS15A	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPS15A	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPS15A	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPS15A	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPS15A	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPS15A	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPS15A	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPS15A	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPS15A	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPS15A	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPS15A	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPS15A	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPS15A	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPS15A	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS15A

EWSR1, ELF5, MGMT, CALM1, CDC37, PCK1, VHL, RAD21, HDGF, CUL3, CUL4A, CUL5, CUL2, CDK2, CUL1, COPS5, COPS6, CAND1, NEDD8, RPL10A, RPL10, RPL11, RPL12, RPL14, RPL15, RPL18A, RPL18, RPL19, RPL21, RPL23, RPL24, RPL27, RPL30, RPL31, RPL37A, RPL4, RPL5, RPL6, RPL7A, RPL7, RPL9, RPS10, RPS11, RPS12, RPS13, RPS14, RPS19, RPS26, RPS3A, RPS3, RPS4X, RPS5, RPS6, RPS7, RPS8, RPSA, RPS23, RPS16, RPS17, RPLP1, RPS24, RPLP2, RPL23A, RPS2, RPLP0, RPS20, RPS15, RPL3, RPL13, RPL38, RPL29, RPS21, RPL17, RPL32, RPS27A, EEF1A1, EEF2, NOP56, FBL, HNRNPU, GNL3, SLC25A5, ILF3, ILF2, NOP58, MOV10, TUFM, NHP2L1, HNRNPM, ACTA2, EIF6, HSP90AA1, RPLP0P6, RPL10L, GALNT2, NOP2, NIFK, MRPS14, UBA2, GNL1, HIST1H2AD, HSPA8, ATP5A1, HNRNPA0, PSMB1, ESR1, SMURF1, FN1, VCAM1, UBL4A, ITGA4, PAN2, PSMC1, PSMC6, PSMD11, PSMD3, FAU, PNO1, PSMD1, RPS18, RPS25, RPS27, RPS27L, RPS29, RPS9, WDR26, WIBG, RPS28, TSR1, ZBTB1, CEP250, CEP57, CEP76, TUBG1, HUWE1, RNF2, EGFR, DIMT1, IMP3, MPHOSPH10, MRPL14, MRPL16, MRPL22, MRPS7, RPL13A, RPL27A, RPL28, RPL34, RPL35, RPL37, DDX18, RPL22, RPL35A, RPL36, RPL8, VAPA, LOC101929876, TUBB, TUBB2B, TUBB4B, UBA52, SFN, PTEN, AHSA1, EXOSC1, Cbx1, Eif3a, Eif3e, Eif3i, Rpl35, Srp72, Rrbp1, UBE3A, MCM2, Ksr1, RHOU, RC3H1, ZNF746, HNRNPA1, CYLD, TRIM25, UBE2A, HEY1, BRCA1, HDAC6, FBXO7, RMND5A, TMPO, ACO2, API5, COPE, CSNK1A1, GSK3A, LARS, ADSL, ADSS, BCL2L1, BMP4, CDK9, CTNNB1, MED12, PCBP1, TGFB1, UBE2L6, PRPF8, AAR2, PIH1D1, EFTUD2, AKTIP, CHD3, CHD4, RIOK1, HEXIM1, MEPCE, LARP7, AGR2, RECQL4, REST, MYC, RPS6KB2, GRWD1, METTL14, KIAA1429, EIF4B, RC3H2, PHB, DISC1, NR2C2, UCHL3, PPP1CC, CTCF, ATXN3, VRK1, VRK3, SNRNP70, ITFG1, ARAF, HMGB1, ABCC6, BIRC3, NFX1, WWP2, SOX2, TRIM28, ARIH2, PLEKHA4, PINK1, YAP1, TFCP2, FANCD2, ZC3H18, ANKRD55, ERCC6, DDX19B, IGF2BP1, NXF1, PARN, DUX4, CIT, ANLN, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, AUH, LONP1, FASN, CLPP, LRRC59, INS, NDN, BRD4, NINL, CIC, Apc2, TMEM259, RBM39, FBP1, LGALS9, RIN3, DDX58, BAG5, PARK2, UFL1, DDRGK1, COIL, DHFRL1, LAMTOR1, ATG10, ATG3, FZR1, UBC, PAGE4, FAT4, RPSAP58, ZNF346, SPRTN, BTF3, FBXW7, UBR5, nsp1, RCHY1, CCNF, PSMD9, ZEB1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RPS15A	chr16	18799385	C	T	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_20	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RPS15A	chr16	18799615	C	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS15A	chr16	18800638	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPS15A	UCEC	chr16	18794371	18794371	C	T	Missense_Mutation	p.R118Q	2
RPS15A	UCEC	chr16	18794397	18794397	G	A	Silent	p.G109	2
RPS15A	READ	chr16	18796086	18796086	A	C	Missense_Mutation	p.N91K	1
RPS15A	SARC	chr16	18800247	18800247	C	T	RNA	NULL	1
RPS15A	SKCM	chr16	18794349	18794349	G	A	Silent	p.I125I	1
RPS15A	BLCA	chr16	18796141	18796141	C	A	Missense_Mutation		1
RPS15A	UCEC	chr16	18794397	18794397	G	A	Silent	p.G109G	1
RPS15A	ESCA	chr16	18795982	18795983	-	A	RNA	NULL	1
RPS15A	HNSC	chr16	18796110	18796110	G	C	Silent		1
RPS15A	HNSC	chr16	18796121	18796121	C	T	Missense_Mutation		1
RPS15A	HNSC	chr16	18796110	18796110	G	C	Silent	p.L83L	1
RPS15A	HNSC	chr16	18796121	18796121	C	T	Missense_Mutation	p.D80N	1
RPS15A	LIHC	chr16	18799445	18799445	T	C	Silent		1
RPS15A	LIHC	chr16	18796111	18796111	A	G	Missense_Mutation		1

Copy number variation (CNV) of RPS15A
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS15A
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
99238	N/A	AK054921	CDR1	chrX	139866517	+	RPS15A	chr16	18801656	-
99238	COAD	TCGA-5M-AAT4-01A	KIAA0907	chr1	155884004	-	RPS15A	chr16	18801659	-
99238	N/A	AW772792	P2RY6	chr11	72984135	-	RPS15A	chr16	18794291	+
99238	Non-Cancer	5381N	PGA3	chr11	60975962	+	RPS15A	chr16	18800440	-
99238	LIHC	TCGA-BC-A10T-01A	PKD1	chr16	2185476	-	RPS15A	chr16	18796145	-
99238	READ	TCGA-AG-3586	PTPRK	chr6	128505576	-	RPS15A	chr16	18800440	-
84059	BRCA	TCGA-A2-A0D2-01A	RPS15A	chr16	18796060	-	ARL6IP1	chr16	18810156	-
90077	N/A	BM015299	RPS15A	chr16	18794291	-	CLNS1A	chr11	77256179	+
77428	N/A	BE737542	RPS15A	chr16	18794290	-	LEPROTL1	chr8	29974849	-
77428	N/A	CF123929	RPS15A	chr16	18794291	-	LEPROTL1	chr8	29974886	-
92573	STAD	TCGA-CD-5798-01A	RPS15A	chr16	18799385	-	PICALM	chr11	85689136	-
101492	N/A	BI856629	RPS15A	chr16	18794285	-	PNPLA8	chr7	108138445	+
77428	STAD	TCGA-CD-A48C-01A	RPS15A	chr16	18800338	-	RHOG	chr11	3848287	-
89508	N/A	BI860288	RPS15A	chr16	18794291	-	TMTC2	chr12	83489029	-
99238	BRCA	TCGA-A2-A0CM-01A	SMG1	chr16	18937272	-	RPS15A	chr16	18800440	-
99238	N/A	BE716419	SPRR3	chr1	152976131	+	RPS15A	chr16	18800992	+
99238	N/A	AI076857	TSNAX-DISC1	chr1	231713444	+	RPS15A	chr16	18794277	+
99242	N/A	AW772569	WHSC1	chr4	1900438	+	RPS15A	chr16	18794290	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPS15A	0.00607538742026996	0.17
ACC	RPS15A	0.0469424239747989	1

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	RPS15A	0.00222669927988954	0.073
LGG	RPS15A	0.0446885084952609	1
BRCA	RPS15A	0.0354070664924308	1
PAAD	RPS15A	0.00767493444165259	0.25

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C1260899	Anemia, Diamond-Blackfan	1	ORPHANET
C2931850	Aase Smith syndrome 2	1	ORPHANET