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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPS17 (NCBI Gene ID:6218)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPS17
	Gene ID: 6218
	Gene Symbol	RPS17
	Gene ID	6218
	Gene Name	ribosomal protein S17
	Synonyms	DBA4\|RPS17L\|RPS17L1\|RPS17L2\|S17
	Cytomap	15q25.2
	Type of Gene	protein-coding
	Description	40S ribosomal protein S17small ribosomal subunit protein eS17
	Modification date	20200313
	UniProtAcc	P08708

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006413	Translational initiation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPS17	(733 - 1119.25]

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Translation Studies in PubMed

We searched PubMed using 'RPS17[title] AND translation [title] AND human.'

Gene	Title	PMID
RPS17	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KICH	RPS17	-9.74128123960814	0.000556409358978271
HNSC	RPS17	-1.41932406270792	0.00608886057921154
KIRC	RPS17	-1.14106059335771	1.12651178935203e-06

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
GBM	RPS17	0.119115619	0.029152604
LGG	RPS17	0.051478636	0.030179778

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPS17 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	RPS17	SNRPD2	0.806270215	2.33E-11
CHOL	CGC	RPS17	NACA	0.838840511	6.29E-13
CHOL	Epifactor	RPS17	FBL	0.803069637	3.20E-11
DLBC	Cell metabolism gene	RPS17	FAU	0.801637237	7.61E-12
DLBC	Cell metabolism gene	RPS17	HSCB	0.810705374	2.88E-12
DLBC	Cell metabolism gene	RPS17	SNRPD2	0.848059372	2.81E-14
DLBC	Cell metabolism gene	RPS17	TOMM22	0.849790554	2.20E-14
DLBC	Cell metabolism gene	RPS17	NME2	0.85107516	1.84E-14
DLBC	CGC	RPS17	NACA	0.851944477	1.62E-14
DLBC	Epifactor	RPS17	FBL	0.821133746	8.82E-13
DLBC	TF	RPS17	NME2	0.85107516	1.84E-14
DLBC	TSG	RPS17	GNB2L1	0.878962887	2.13E-16
GBM	TSG	RPS17	GAS5	0.823403727	1.09E-43
PRAD	Cell metabolism gene	RPS17	SNRPD2	0.804786038	3.07E-126
PRAD	CGC	RPS17	NACA	0.815258345	4.06E-132
PRAD	Epifactor	RPS17	FBL	0.816176305	1.19E-132
PRAD	TSG	RPS17	GAS5	0.811293114	7.54E-130
PRAD	TSG	RPS17	GNB2L1	0.826512429	7.23E-139
THYM	Cell metabolism gene	RPS17	SNRPD1	0.800447329	1.92E-28
THYM	Cell metabolism gene	RPS17	SNRPE	0.801415747	1.48E-28
THYM	Cell metabolism gene	RPS17	PSMC3	0.802553706	1.08E-28
THYM	Cell metabolism gene	RPS17	PFDN5	0.803528736	8.31E-29
THYM	Cell metabolism gene	RPS17	EBP	0.806046836	4.16E-29
THYM	Cell metabolism gene	RPS17	ITPA	0.808681406	1.99E-29
THYM	Cell metabolism gene	RPS17	SSR2	0.809122348	1.76E-29
THYM	Cell metabolism gene	RPS17	PSMB3	0.814870889	3.37E-30
THYM	Cell metabolism gene	RPS17	EXOSC5	0.816312994	2.21E-30
THYM	Cell metabolism gene	RPS17	PSMB7	0.8250633	1.56E-31
THYM	Cell metabolism gene	RPS17	TIMM13	0.825190779	1.50E-31
THYM	Cell metabolism gene	RPS17	SNRPD3	0.827549902	7.14E-32
THYM	Cell metabolism gene	RPS17	POLR2H	0.829186192	4.25E-32
THYM	Cell metabolism gene	RPS17	HMBS	0.832150732	1.63E-32
THYM	Cell metabolism gene	RPS17	FAU	0.839051749	1.63E-33
THYM	Cell metabolism gene	RPS17	SLC27A5	0.840873306	8.74E-34
THYM	Cell metabolism gene	RPS17	SNRPD2	0.84956148	3.95E-35
THYM	Cell metabolism gene	RPS17	TIMM8B	0.853492705	9.12E-36
THYM	Epifactor	RPS17	NOC2L	0.809149254	1.74E-29
THYM	Epifactor	RPS17	EXOSC5	0.816312994	2.21E-30
THYM	Epifactor	RPS17	SIRT6	0.820020126	7.31E-31
THYM	Epifactor	RPS17	BRMS1	0.83879938	1.78E-33
THYM	Epifactor	RPS17	TAF10	0.84641784	1.24E-34
THYM	Epifactor	RPS17	FBL	0.847592875	8.10E-35
THYM	IUPHAR	RPS17	SIRT6	0.820020126	7.31E-31
THYM	IUPHAR	RPS17	SLC27A5	0.840873306	8.74E-34
THYM	TF	RPS17	ZNF511	0.80368251	7.97E-29
THYM	TF	RPS17	ZNF787	0.805056717	5.47E-29
THYM	TSG	RPS17	SIRT6	0.820020126	7.31E-31
THYM	TSG	RPS17	GNB2L1	0.833807787	9.48E-33
THYM	TSG	RPS17	BRMS1	0.83879938	1.78E-33
UCS	Cell metabolism gene	RPS17	SNRPD1	0.800447329	1.92E-28
UCS	Cell metabolism gene	RPS17	SNRPE	0.801415747	1.48E-28
UCS	Cell metabolism gene	RPS17	PSMC3	0.802553706	1.08E-28
UCS	Cell metabolism gene	RPS17	PFDN5	0.803528736	8.31E-29
UCS	Cell metabolism gene	RPS17	EBP	0.806046836	4.16E-29
UCS	Cell metabolism gene	RPS17	ITPA	0.808681406	1.99E-29
UCS	Cell metabolism gene	RPS17	SSR2	0.809122348	1.76E-29
UCS	Cell metabolism gene	RPS17	PSMB3	0.814870889	3.37E-30
UCS	Cell metabolism gene	RPS17	EXOSC5	0.816312994	2.21E-30
UCS	Cell metabolism gene	RPS17	PSMB7	0.8250633	1.56E-31
UCS	Cell metabolism gene	RPS17	TIMM13	0.825190779	1.50E-31
UCS	Cell metabolism gene	RPS17	SNRPD3	0.827549902	7.14E-32
UCS	Cell metabolism gene	RPS17	POLR2H	0.829186192	4.25E-32
UCS	Cell metabolism gene	RPS17	HMBS	0.832150732	1.63E-32
UCS	Cell metabolism gene	RPS17	FAU	0.839051749	1.63E-33
UCS	Cell metabolism gene	RPS17	SLC27A5	0.840873306	8.74E-34
UCS	Cell metabolism gene	RPS17	SNRPD2	0.84956148	3.95E-35
UCS	Cell metabolism gene	RPS17	TIMM8B	0.853492705	9.12E-36
UCS	Epifactor	RPS17	NOC2L	0.809149254	1.74E-29
UCS	Epifactor	RPS17	EXOSC5	0.816312994	2.21E-30
UCS	Epifactor	RPS17	SIRT6	0.820020126	7.31E-31
UCS	Epifactor	RPS17	BRMS1	0.83879938	1.78E-33
UCS	Epifactor	RPS17	TAF10	0.84641784	1.24E-34
UCS	Epifactor	RPS17	FBL	0.847592875	8.10E-35
UCS	IUPHAR	RPS17	SIRT6	0.820020126	7.31E-31
UCS	IUPHAR	RPS17	SLC27A5	0.840873306	8.74E-34
UCS	TF	RPS17	ZNF511	0.80368251	7.97E-29
UCS	TF	RPS17	ZNF787	0.805056717	5.47E-29
UCS	TSG	RPS17	SIRT6	0.820020126	7.31E-31
UCS	TSG	RPS17	GNB2L1	0.833807787	9.48E-33
UCS	TSG	RPS17	BRMS1	0.83879938	1.78E-33
UVM	Cell metabolism gene	RPS17	SEC11A	0.835069859	6.13E-22

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPS17	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPS17	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPS17	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPS17	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPS17	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPS17	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPS17	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPS17	RPL19	1.36901182894089	0.00250792503356934
KICH	RPS17	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPS17	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPS17	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPS17	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPS17	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPS17	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPS17	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPS17	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPS17	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPS17	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPS17	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPS17	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPS17	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPS17	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPS17	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPS17	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPS17	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPS17	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPS17	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPS17	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPS17

CACNA1A, EBNA-LP, VHL, RAD21, ARRB1, ARRB2, CUL3, CDK2, CUL1, COPS5, CAND1, RPS4X, RPL14, RPL19, RPL21, RPL24, RPL27, RPL31, RPL37A, RPL6, RPLP2, RPS24, RPSA, RPS23, RPS16, RPL10, RPS2, RPS15A, RPL5, RPS26, RPL9, RPL12, RPS28, RPL23, RPL4, RPLP1, RPS9, RPL22, RPS15, RPS8, RPS7, RPS3A, RPS25, RPS3, RPL8, RPS13, RPL18, RPS6, RPS21, FAU, RPS29, ILF3, RBM28, RPLP0P6, SMURF1, FN1, VCAM1, NOS2, UBL4A, ITGA4, UL122, PAN2, TARDBP, RPS11, RPS10, RPS19, RPS20, rev, CDC37L1, NUDC, CEP250, CEP57, CEP76, TP53, TUBG1, TUBGCP3, HUWE1, RNF2, WDR76, FRMD5, RPS6KB2, RPL23A, RPLP0, LOC101929876, PTEN, XPO1, HIST1H3E, HNRNPU, NPM1, CKAP5, Cbx1, Ktn1, Rpl35, Srp72, Rrbp1, CRY2, MCM2, RC3H1, CDC73, ZNF746, HIST1H1E, RRS1, BHLHA15, NCL, CYLD, FOXA1, TRIM25, HEY1, HDAC6, TMPO, CTNNB1, HDAC4, YAF2, PRPF8, EFTUD2, AAR2, PIH1D1, RPTOR, CHD3, CHD4, LARP7, RNF31, TNF, CDC34, RIOK1, HEXIM1, MEPCE, RECQL4, REST, MYC, CDK9, Prkab1, GRWD1, KIAA1429, EIF4B, RC3H2, ZBTB7A, PHB, RBX1, PPP1CC, VRK1, VRK3, HIST1H4A, SNRNP70, DUSP15, DUSP5, MTMR2, PTP4A3, PTPN3, PTPN6, ITFG1, HMGB1, BIRC3, NFX1, ORF9b, SOX2, TRIM28, CMTR1, ARIH2, PLEKHA4, YAP1, TFCP2, FANCD2, HCVgp1, ZC3H18, ESR1, NEK4, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, LRRC59, INS, BRD4, NUPR1, CIC, N, Apc2, RBM39, ASXL1, BAG5, UFL1, DDRGK1, ATG3, FZR1, ZBTB2, SRSF5, HIST1H1C, KRR1, HIST1H1B, HIST2H2AC, LIN28A, YBX2, HIST1H2AM, RPSAP58, FGF13, HIST1H1D, S100P, HIST1H2AE, SURF6, RPL35, ZNF346, SRSF6, HIST1H1A, NEIL1, SPRTN, BTF3, FBXW7, RCHY1, SQSTM1, PSMD9, Paxip1, PAGR1, Wdr82, KLF15, KLF16, KLF5, KLF8, SOX5, SOX6,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RPS17	chr15	82821296	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RPS17	chr15	82822729	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant
RPS17	chr15	82823346	CCT	C	Microsatellite	Pathogenic	Diamond-Blackfan_anemia_4	SO:0001589\|frameshift_variant,SO:0001619\|non-coding_transcript_variant	SO:0001589\|frameshift_variant,SO:0001619\|non-coding_transcript_variant
RPS17	chr15	82823390	A	C	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_4	SO:0001587\|nonsense,SO:0001619\|non-coding_transcript_variant	SO:0001587\|nonsense,SO:0001619\|non-coding_transcript_variant
RPS17	chr15	82823390	A	G	single_nucleotide_variant	Uncertain_significance	not_specified	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant	SO:0001619\|non-coding_transcript_variant,SO:0001819\|synonymous_variant
RPS17	chr15	82824389	CCTG	C	Deletion	Uncertain_significance	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001822\|inframe_deletion	SO:0001619\|non-coding_transcript_variant,SO:0001822\|inframe_deletion
RPS17	chr15	82824702	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001619\|non-coding_transcript_variant,SO:0001627\|intron_variant	SO:0001619\|non-coding_transcript_variant,SO:0001627\|intron_variant
RPS17	chr15	82824835	A	C	single_nucleotide_variant	Pathogenic	Diamond-Blackfan_anemia_4	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant	SO:0001582\|initiatior_codon_variant,SO:0001583\|missense_variant,SO:0001619\|non-coding_transcript_variant
RPS17	chr15	82824890	A	T	single_nucleotide_variant	Benign	not_provided

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene

Cancer type

Chromosome

Start

End

RefSeeq

MutSeq

Mutation type

AAchange

# samples

Copy number variation (CNV) of RPS17
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPS17
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
101497	N/A	AA535940	C2orf91	chr2	42178588	+	RPS17	chr15	83205503	+
101497	N/A	BF244993	CAPNS1	chr19	36640761	+	RPS17	chr15	83209190	-
101497	N/A	AI969969	CCDC149	chr4	24868413	-	RPS17	chr15	83205504	+
101497	N/A	EC559380	DNAH12	chr3	57491138	-	RPS17	chr15	83208885	-
99621	N/A	BI862080	RPS17	chr15	83205503	-	ANK3	chr10	62108102	+
96510	N/A	BE905390	RPS17	chr15	83205504	-	C11orf80	chr11	66516340	+
82388	N/A	BF687839	RPS17	chr15	83205509	-	C20orf196	chr20	5805289	-
92661	OV	TCGA-04-1357-01A	RPS17	chr15	82823333	-	CD74	chr5	149792312	-
77498	N/A	CD240141	RPS17	chr15	83205506	-	CES5AP1	chr22	23720126	+
77498	PRAD	TCGA-KC-A4BN	RPS17	chr15	82822714	-	CHAF1B	chr21	37759896	+
77498	PRAD	TCGA-KC-A4BN-01A	RPS17	chr15	83207057	-	CHAF1B	chr21	37759896	+
102842	N/A	AA527955	RPS17	chr15	83205503	-	DAB1	chr1	58573140	+
86779	N/A	BM015885	RPS17	chr15	83205503	-	KLHL28	chr14	45406361	-
87220	N/A	BG032138	RPS17	chr15	83205504	-	MAP7	chr6	136724043	+
77498	N/A	CB219922	RPS17	chr15	83207104	-	PTPN7	chr1	202116297	+
101497	N/A	AX340711	RPS17	chr15	83205570	-	RPS17	chr15	83208799	-
91964	N/A	BI856351	RPS17	chr15	83205506	-	SNX29	chr16	12566388	+
101916	OV	TCGA-25-1313-01A	RPS17	chr15	82823337	-	SPP1	chr4	88896865	+
101916	OV	TCGA-61-2000-01A	RPS17	chr15	82823332	-	SPP1	chr4	88896869	+
101916	OV	TCGA-61-2109-01A	RPS17	chr15	82823336	-	SPP1	chr4	88896865	+
102816	N/A	AX341364	RPS17	chr15	83208882	+	SPTBN1	chr2	54896741	-
101110	N/A	BG034564	RPS17	chr15	83205506	-	YPEL1	chr22	22078879	-
77498	N/A	AA506679	RPS17	chr15	83205512	-	ZNF141	chr4	336753	-
77498	N/A	BC022370	RPS17	chr15	83205509	-	ZNF141	chr4	336753	-
77498	N/A	BG032122	RPS17	chr15	83205504	-	ZNF141	chr4	336753	-
77498	N/A	CN446909	RPS17	chr15	83205503	-	ZNF141	chr4	336753	-
101497	Non-Cancer	TCGA-IN-8462-11A	SEC11A	chr15	85259256	-	RPS17	chr15	82824540	-
101497	N/A	AA533301	TYRO3	chr15	41857799	+	RPS17	chr15	83205506	+
101497	N/A	AA858143	XKR6	chr8	11025410	-	RPS17	chr15	83205506	+
101501	N/A	AA229106	ZNF141	chr4	336753	+	RPS17	chr15	83205506	+
101501	N/A	AA513246	ZNF141	chr4	336753	+	RPS17	chr15	83205504	+
101501	N/A	AA654541	ZNF141	chr4	336753	+	RPS17	chr15	83205503	+
101501	N/A	BE838490	ZNF141	chr4	336753	+	RPS17	chr15	83207056	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPS17	0.000154580856503454	0.0043
TGCT	RPS17	0.0125340540793406	0.34
MESO	RPS17	0.0250556421457006	0.65

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
STAD	RPS17	0.0294886435285043	0.91
LUSC	RPS17	0.0263148221516904	0.84
LGG	RPS17	0.037144187923708	1
BRCA	RPS17	1.26025794953158e-05	0.00042

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C2675860	Diamond-Blackfan Anemia 4	3	CTD_human;GENOMICS_ENGLAND
C1260899	Anemia, Diamond-Blackfan	2	CTD_human;GENOMICS_ENGLAND