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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: MRPS15 (NCBI Gene ID:64960)

Gene Summary

Gene Summary

Gene Information	Gene Name: MRPS15
	Gene ID: 64960
	Gene Symbol	MRPS15
	Gene ID	64960
	Gene Name	mitochondrial ribosomal protein S15
	Synonyms	DC37\|MPR-S15\|RPMS15\|S15mt
	Cytomap	1p34.3
	Type of Gene	protein-coding
	Description	28S ribosomal protein S15, mitochondrialMRP-S15mitochondrial small ribosomal subunit protein uS15m
	Modification date	20200313
	UniProtAcc	P82914

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0032543	Mitochondrial translation
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
MRPS15	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'MRPS15[title] AND translation [title] AND human.'

Gene	Title	PMID
MRPS15	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000373116	36923523	36923582	Frame-shift
ENST00000373116	36926292	36926377	Frame-shift
ENST00000373116	36926864	36926913	Frame-shift
ENST00000373116	36927688	36927764	Frame-shift

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
BRCA	MRPS15	-2.19567551682318	0.000188684660674703
KIRC	MRPS15	1.11572283836012	0.00361818577801855
THCA	MRPS15	-1.19960602422995	0.0140154883942907

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
UCS	MRPS15	-0.03501909	0.024227287
DLBC	MRPS15	-0.024168455	0.04649578

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with MRPS15 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
DLBC	Cell metabolism gene	MRPS15	SNRPE	0.801262837	7.91E-12
DLBC	Cell metabolism gene	MRPS15	ANP32A	0.806141799	4.73E-12
DLBC	Cell metabolism gene	MRPS15	HSCB	0.806896674	4.36E-12
DLBC	Cell metabolism gene	MRPS15	MIF	0.810201312	3.04E-12
DLBC	Cell metabolism gene	MRPS15	AK2	0.815270277	1.73E-12
DLBC	Cell metabolism gene	MRPS15	FPGS	0.816593441	1.49E-12
DLBC	Cell metabolism gene	MRPS15	SNRPB	0.819615982	1.05E-12
DLBC	Cell metabolism gene	MRPS15	PSMB3	0.823095926	7.00E-13
DLBC	Cell metabolism gene	MRPS15	PTDSS2	0.831075607	2.65E-13
DLBC	Cell metabolism gene	MRPS15	POLR2I	0.835724234	1.47E-13
DLBC	Cell metabolism gene	MRPS15	PMPCA	0.837925259	1.11E-13
DLBC	Cell metabolism gene	MRPS15	ATP5G1	0.839022255	9.59E-14
DLBC	Cell metabolism gene	MRPS15	PSMD13	0.8419305	6.52E-14
DLBC	Cell metabolism gene	MRPS15	PSMB7	0.842060488	6.40E-14
DLBC	Cell metabolism gene	MRPS15	PSMC3	0.842870785	5.74E-14
DLBC	Cell metabolism gene	MRPS15	TOMM22	0.843162395	5.52E-14
DLBC	Cell metabolism gene	MRPS15	PSMA4	0.843207476	5.49E-14
DLBC	Cell metabolism gene	MRPS15	TIMM50	0.848166114	2.77E-14
DLBC	Cell metabolism gene	MRPS15	IDH3B	0.852235308	1.55E-14
DLBC	Cell metabolism gene	MRPS15	POLR2F	0.859897485	4.98E-15
DLBC	Cell metabolism gene	MRPS15	NME2	0.868581635	1.26E-15
DLBC	Cell metabolism gene	MRPS15	TIMM13	0.868731596	1.23E-15
DLBC	Cell metabolism gene	MRPS15	POLR2L	0.881522884	1.34E-16
DLBC	Cell metabolism gene	MRPS15	SNRPD3	0.895474369	8.78E-18
DLBC	Cell metabolism gene	MRPS15	SNRPD2	0.918837551	3.38E-20
DLBC	CGC	MRPS15	HRAS	0.823037606	7.05E-13
DLBC	Epifactor	MRPS15	ANP32A	0.806141799	4.73E-12
DLBC	Epifactor	MRPS15	RUVBL2	0.806638393	4.48E-12
DLBC	Epifactor	MRPS15	PRPF31	0.80676145	4.42E-12
DLBC	Epifactor	MRPS15	FBL	0.875765984	3.75E-16
DLBC	IUPHAR	MRPS15	MFSD2B	0.81369117	2.07E-12
DLBC	IUPHAR	MRPS15	BIRC5	0.821714201	8.24E-13
DLBC	IUPHAR	MRPS15	HRAS	0.823037606	7.05E-13
DLBC	TF	MRPS15	PIN1	0.803493065	6.26E-12
DLBC	TF	MRPS15	NME2	0.868581635	1.26E-15
DLBC	TSG	MRPS15	PIN1	0.803493065	6.26E-12
DLBC	TSG	MRPS15	ANP32A	0.806141799	4.73E-12
DLBC	TSG	MRPS15	PHB	0.832114265	2.33E-13
DLBC	TSG	MRPS15	GADD45GIP1	0.858729698	5.95E-15
DLBC	TSG	MRPS15	PARK7	0.879015734	2.11E-16
GBM	Cell metabolism gene	MRPS15	SDHC	0.801651534	7.84E-40
GBM	Cell metabolism gene	MRPS15	SNRPD2	0.807657097	7.57E-41
GBM	Cell metabolism gene	MRPS15	PSMA7	0.809097928	4.27E-41
GBM	Cell metabolism gene	MRPS15	NME2	0.810187286	2.76E-41
GBM	Cell metabolism gene	MRPS15	PSMD14	0.815372851	3.32E-42
GBM	Cell metabolism gene	MRPS15	SDHB	0.821037037	3.04E-43
GBM	Cell metabolism gene	MRPS15	PFDN5	0.830460557	4.69E-45
GBM	Cell metabolism gene	MRPS15	PSMD13	0.835258391	5.08E-46
GBM	Cell metabolism gene	MRPS15	PSMB3	0.840529706	4.06E-47
GBM	Cell metabolism gene	MRPS15	PSMB4	0.84907771	5.51E-49
GBM	Cell metabolism gene	MRPS15	SNRPG	0.857482107	6.16E-51
GBM	Cell metabolism gene	MRPS15	PSMA5	0.888468785	2.16E-59
GBM	CGC	MRPS15	SDHC	0.801651534	7.84E-40
GBM	CGC	MRPS15	SDHB	0.821037037	3.04E-43
GBM	Epifactor	MRPS15	ZNHIT1	0.807523084	7.98E-41
GBM	Epifactor	MRPS15	DPY30	0.858230239	4.07E-51
GBM	IUPHAR	MRPS15	PDZD11	0.814350974	5.06E-42
GBM	IUPHAR	MRPS15	PSMD14	0.815372851	3.32E-42
GBM	IUPHAR	MRPS15	ATP6V0B	0.861046018	8.39E-52
GBM	TF	MRPS15	NME2	0.810187286	2.76E-41
GBM	TF	MRPS15	GTF2B	0.814320399	5.12E-42
GBM	TSG	MRPS15	SDHB	0.821037037	3.04E-43
KIRP	TSG	MRPS15	GADD45GIP1	0.804946048	9.42E-75
LGG	Cell metabolism gene	MRPS15	PSMA5	0.817608456	1.10E-128
LGG	Cell metabolism gene	MRPS15	UROD	0.831250517	9.50E-137
LGG	Cell metabolism gene	MRPS15	MED8	0.851011364	8.29E-150
LGG	IUPHAR	MRPS15	ATP6V0B	0.845183251	9.11E-146
PRAD	Cell metabolism gene	MRPS15	DPM2	0.803319237	1.91E-125
PRAD	Cell metabolism gene	MRPS15	FAU	0.805061138	2.17E-126
PRAD	Cell metabolism gene	MRPS15	NME1	0.806169682	5.38E-127
PRAD	Cell metabolism gene	MRPS15	PGLS	0.808974338	1.51E-128
PRAD	Cell metabolism gene	MRPS15	DPM3	0.816028885	1.45E-132
PRAD	Cell metabolism gene	MRPS15	SNRPD2	0.82390607	2.92E-137
PRAD	Cell metabolism gene	MRPS15	LSM4	0.827130037	2.98E-139
PRAD	Cell metabolism gene	MRPS15	PSMB7	0.836410108	3.21E-145
PRAD	Cell metabolism gene	MRPS15	PFDN6	0.837365694	7.43E-146
PRAD	Cell metabolism gene	MRPS15	POLR2F	0.838158074	2.19E-146
PRAD	Cell metabolism gene	MRPS15	ATP5G1	0.838501726	1.29E-146
PRAD	Cell metabolism gene	MRPS15	PSMB3	0.841766494	7.74E-149
PRAD	Cell metabolism gene	MRPS15	TIMM50	0.848659944	1.07E-153
PRAD	Cell metabolism gene	MRPS15	POLR2I	0.854039135	1.16E-157
PRAD	Cell metabolism gene	MRPS15	HSD17B10	0.856966685	6.94E-160
PRAD	Epifactor	MRPS15	RBX1	0.831131474	8.83E-142
PRAD	Epifactor	MRPS15	ZNHIT1	0.842156876	4.17E-149
PRAD	Epifactor	MRPS15	TAF10	0.874836518	1.23E-174
PRAD	IUPHAR	MRPS15	CSNK2B	0.826689396	5.61E-139
PRAD	TF	MRPS15	GTF3A	0.800703433	4.81E-124
PRAD	TSG	MRPS15	NME1	0.806169682	5.38E-127
PRAD	TSG	MRPS15	PARK7	0.819834243	8.34E-135
PRAD	TSG	MRPS15	GADD45GIP1	0.879968481	2.70E-179
TGCT	Cell metabolism gene	MRPS15	TIMM8B	0.800740614	4.24E-36
TGCT	Cell metabolism gene	MRPS15	SNRPF	0.825733601	3.92E-40
TGCT	Cell metabolism gene	MRPS15	NT5C	0.835924667	5.74E-42
TGCT	Cell metabolism gene	MRPS15	PSMB3	0.850166574	9.42E-45
TGCT	Epifactor	MRPS15	ZNHIT1	0.804051739	1.34E-36
TGCT	IUPHAR	MRPS15	CSNK2B	0.819365096	4.79E-39
TGCT	IUPHAR	MRPS15	PPIA	0.823619106	9.10E-40
TGCT	IUPHAR	MRPS15	NT5C	0.835924667	5.74E-42
THCA	Cell metabolism gene	MRPS15	TIMM8B	0.801363927	2.59E-129
THCA	Cell metabolism gene	MRPS15	MTX1	0.804652477	3.72E-131
THCA	Cell metabolism gene	MRPS15	POLR2J	0.807317336	1.13E-132
THCA	Cell metabolism gene	MRPS15	PFDN6	0.815793769	1.14E-137
THCA	Cell metabolism gene	MRPS15	COX17	0.816658692	3.42E-138
THCA	CGC	MRPS15	COX6C	0.841244757	2.31E-154
THCA	IUPHAR	MRPS15	PPIA	0.807287822	1.17E-132
THCA	IUPHAR	MRPS15	SLC25A39	0.815149616	2.79E-137
THCA	TF	MRPS15	GTF3A	0.801112448	3.56E-129
THYM	Cell metabolism gene	MRPS15	GMPPA	0.80437988	6.58E-29
THYM	Cell metabolism gene	MRPS15	DHRS4	0.805601696	4.70E-29
THYM	Cell metabolism gene	MRPS15	NT5M	0.806720865	3.45E-29
THYM	Cell metabolism gene	MRPS15	HMOX2	0.807294302	2.94E-29
THYM	Cell metabolism gene	MRPS15	TOMM5	0.809520038	1.57E-29
THYM	Cell metabolism gene	MRPS15	SNRPE	0.80956285	1.55E-29
THYM	Cell metabolism gene	MRPS15	PMPCA	0.810470192	1.20E-29
THYM	Cell metabolism gene	MRPS15	DHRS4L2	0.815076012	3.18E-30
THYM	Cell metabolism gene	MRPS15	NME1	0.816158633	2.31E-30
THYM	Cell metabolism gene	MRPS15	MED27	0.817292805	1.65E-30
THYM	Cell metabolism gene	MRPS15	PPCDC	0.819000929	9.93E-31
THYM	Cell metabolism gene	MRPS15	SMPD2	0.819768831	7.88E-31
THYM	Cell metabolism gene	MRPS15	PCYT2	0.821498671	4.67E-31
THYM	Cell metabolism gene	MRPS15	MIF	0.821874791	4.16E-31
THYM	Cell metabolism gene	MRPS15	TSTA3	0.823778498	2.32E-31
THYM	Cell metabolism gene	MRPS15	DGAT1	0.825501081	1.36E-31
THYM	Cell metabolism gene	MRPS15	POLD2	0.8260538	1.14E-31
THYM	Cell metabolism gene	MRPS15	TAZ	0.826395666	1.03E-31
THYM	Cell metabolism gene	MRPS15	GALK1	0.826743159	9.22E-32
THYM	Cell metabolism gene	MRPS15	APOA1	0.827503503	7.25E-32
THYM	Cell metabolism gene	MRPS15	HMBS	0.828005693	6.18E-32
THYM	Cell metabolism gene	MRPS15	COX17	0.828027482	6.14E-32
THYM	Cell metabolism gene	MRPS15	PFDN4	0.828823714	4.77E-32
THYM	Cell metabolism gene	MRPS15	FPGS	0.828865026	4.71E-32
THYM	Cell metabolism gene	MRPS15	ATP5G1	0.829419724	3.94E-32
THYM	Cell metabolism gene	MRPS15	LSM3	0.830760106	2.56E-32
THYM	Cell metabolism gene	MRPS15	SNRPD1	0.835392769	5.61E-33
THYM	Cell metabolism gene	MRPS15	IDH3G	0.835660223	5.13E-33
THYM	Cell metabolism gene	MRPS15	PSMB4	0.837159749	3.10E-33
THYM	Cell metabolism gene	MRPS15	GSS	0.837548499	2.72E-33
THYM	Cell metabolism gene	MRPS15	SNRPB	0.838296617	2.11E-33
THYM	Cell metabolism gene	MRPS15	PSMC5	0.838681869	1.85E-33
THYM	Cell metabolism gene	MRPS15	TOMM22	0.844118291	2.81E-34
THYM	Cell metabolism gene	MRPS15	DTYMK	0.845304499	1.84E-34
THYM	Cell metabolism gene	MRPS15	SRM	0.846906766	1.04E-34
THYM	Cell metabolism gene	MRPS15	SEC61G	0.848371446	6.11E-35
THYM	Cell metabolism gene	MRPS15	GEMIN7	0.849100089	4.68E-35
THYM	Cell metabolism gene	MRPS15	PFDN5	0.850607945	2.68E-35
THYM	Cell metabolism gene	MRPS15	MVD	0.852152047	1.51E-35
THYM	Cell metabolism gene	MRPS15	NANS	0.852332959	1.41E-35
THYM	Cell metabolism gene	MRPS15	EXOSC5	0.855909896	3.62E-36
THYM	Cell metabolism gene	MRPS15	TXN	0.857077165	2.31E-36
THYM	Cell metabolism gene	MRPS15	DPM2	0.858387921	1.38E-36
THYM	Cell metabolism gene	MRPS15	LSM5	0.858607602	1.27E-36
THYM	Cell metabolism gene	MRPS15	UROS	0.859160824	1.02E-36
THYM	Cell metabolism gene	MRPS15	PSME2	0.860653277	5.64E-37
THYM	Cell metabolism gene	MRPS15	POLR2F	0.862272781	2.94E-37
THYM	Cell metabolism gene	MRPS15	LSM2	0.863081818	2.12E-37
THYM	Cell metabolism gene	MRPS15	EXOSC4	0.864316231	1.28E-37
THYM	Cell metabolism gene	MRPS15	SNRPD3	0.864420277	1.22E-37
THYM	Cell metabolism gene	MRPS15	PSMB6	0.86475665	1.07E-37
THYM	Cell metabolism gene	MRPS15	SLC27A5	0.864997879	9.65E-38
THYM	Cell metabolism gene	MRPS15	SEC61B	0.865039414	9.48E-38
THYM	Cell metabolism gene	MRPS15	TIMM10	0.865103678	9.23E-38
THYM	Cell metabolism gene	MRPS15	TBCB	0.866930922	4.31E-38
THYM	Cell metabolism gene	MRPS15	UROD	0.868168174	2.56E-38
THYM	Cell metabolism gene	MRPS15	PGP	0.869126319	1.70E-38
THYM	Cell metabolism gene	MRPS15	MTX1	0.870473518	9.53E-39
THYM	Cell metabolism gene	MRPS15	PSMB1	0.87098094	7.65E-39
THYM	Cell metabolism gene	MRPS15	HSD17B10	0.872852092	3.37E-39
THYM	Cell metabolism gene	MRPS15	PSMD4	0.874442358	1.67E-39
THYM	Cell metabolism gene	MRPS15	PSMC1	0.876495767	6.60E-40
THYM	Cell metabolism gene	MRPS15	ITPA	0.877147065	4.90E-40
THYM	Cell metabolism gene	MRPS15	GEMIN6	0.88019023	1.20E-40
THYM	Cell metabolism gene	MRPS15	EXOSC1	0.880960295	8.31E-41
THYM	Cell metabolism gene	MRPS15	DPM3	0.88229169	4.41E-41
THYM	Cell metabolism gene	MRPS15	PSMA4	0.883001735	3.14E-41
THYM	Cell metabolism gene	MRPS15	PAFAH1B3	0.884765538	1.33E-41
THYM	Cell metabolism gene	MRPS15	WBSCR22	0.885475155	9.39E-42
THYM	Cell metabolism gene	MRPS15	FAU	0.885527216	9.15E-42
THYM	Cell metabolism gene	MRPS15	SNRPF	0.886185557	6.60E-42
THYM	Cell metabolism gene	MRPS15	GUK1	0.888134694	2.49E-42
THYM	Cell metabolism gene	MRPS15	PSMD13	0.888856994	1.72E-42
THYM	Cell metabolism gene	MRPS15	TIMM17B	0.889414732	1.30E-42
THYM	Cell metabolism gene	MRPS15	PFDN6	0.891307359	4.88E-43
THYM	Cell metabolism gene	MRPS15	POLR2H	0.895818929	4.40E-44
THYM	Cell metabolism gene	MRPS15	DGUOK	0.896525604	2.99E-44
THYM	Cell metabolism gene	MRPS15	TIMM13	0.89928972	6.41E-45
THYM	Cell metabolism gene	MRPS15	PSMC3	0.901240196	2.10E-45
THYM	Cell metabolism gene	MRPS15	PSMB10	0.903357393	6.11E-46
THYM	Cell metabolism gene	MRPS15	EBP	0.904562218	2.99E-46
THYM	Cell metabolism gene	MRPS15	PGLS	0.905716399	1.49E-46
THYM	Cell metabolism gene	MRPS15	ACOT8	0.906086253	1.19E-46
THYM	Cell metabolism gene	MRPS15	LSM4	0.907440676	5.19E-47
THYM	Cell metabolism gene	MRPS15	PHKG2	0.911929384	3.01E-48
THYM	Cell metabolism gene	MRPS15	PSMB7	0.916279753	1.64E-49
THYM	Cell metabolism gene	MRPS15	TOMM40	0.917980388	5.05E-50
THYM	Cell metabolism gene	MRPS15	POLR2J	0.920612704	7.73E-51
THYM	Cell metabolism gene	MRPS15	POLR2I	0.924125484	5.69E-52
THYM	Cell metabolism gene	MRPS15	APRT	0.930426283	3.79E-54
THYM	Cell metabolism gene	MRPS15	SNRPD2	0.93270651	5.49E-55
THYM	Cell metabolism gene	MRPS15	TIMM8B	0.933367025	3.10E-55
THYM	Cell metabolism gene	MRPS15	TIMM50	0.938317041	3.50E-57
THYM	Cell metabolism gene	MRPS15	PSMB3	0.940189072	5.82E-58
THYM	CGC	MRPS15	MAP2K2	0.808706871	1.98E-29
THYM	CGC	MRPS15	RBM10	0.835701737	5.06E-33
THYM	CGC	MRPS15	MGMT	0.852675649	1.24E-35
THYM	CGC	MRPS15	SDHAF2	0.855565044	4.14E-36
THYM	CGC	MRPS15	COX6C	0.887826599	2.91E-42
THYM	CGC	MRPS15	TFPT	0.889474326	1.26E-42
THYM	Epifactor	MRPS15	HIST1H2AJ	0.801775042	1.34E-28
THYM	Epifactor	MRPS15	HIST1H4J	0.803019879	9.55E-29
THYM	Epifactor	MRPS15	CXXC1	0.807686966	2.63E-29
THYM	Epifactor	MRPS15	PPM1G	0.810256184	1.27E-29
THYM	Epifactor	MRPS15	PRMT7	0.811541439	8.83E-30
THYM	Epifactor	MRPS15	PRMT1	0.814665974	3.58E-30
THYM	Epifactor	MRPS15	DMAP1	0.817298896	1.65E-30
THYM	Epifactor	MRPS15	MBD3	0.818610153	1.12E-30
THYM	Epifactor	MRPS15	ACTR5	0.820217728	6.89E-31
THYM	Epifactor	MRPS15	NOC2L	0.824440382	1.89E-31
THYM	Epifactor	MRPS15	RBX1	0.83158849	1.96E-32
THYM	Epifactor	MRPS15	HMG20B	0.831993734	1.72E-32
THYM	Epifactor	MRPS15	LAS1L	0.836629297	3.71E-33
THYM	Epifactor	MRPS15	PAF1	0.839371046	1.46E-33
THYM	Epifactor	MRPS15	SS18L2	0.843080161	4.05E-34
THYM	Epifactor	MRPS15	FBL	0.844461041	2.49E-34
THYM	Epifactor	MRPS15	HIST2H2AC	0.850759586	2.54E-35
THYM	Epifactor	MRPS15	C17orf49	0.851755295	1.75E-35
THYM	Epifactor	MRPS15	CDK5	0.852004578	1.60E-35
THYM	Epifactor	MRPS15	EXOSC5	0.855909896	3.62E-36
THYM	Epifactor	MRPS15	ZGPAT	0.859259787	9.81E-37
THYM	Epifactor	MRPS15	EXOSC4	0.864316231	1.28E-37
THYM	Epifactor	MRPS15	CCDC101	0.880219736	1.18E-40
THYM	Epifactor	MRPS15	EXOSC1	0.880960295	8.31E-41
THYM	Epifactor	MRPS15	PPP4C	0.887651147	3.17E-42
THYM	Epifactor	MRPS15	TFPT	0.889474326	1.26E-42
THYM	Epifactor	MRPS15	RUVBL2	0.901732395	1.58E-45
THYM	Epifactor	MRPS15	PRPF31	0.910750349	6.46E-48
THYM	Epifactor	MRPS15	SIRT6	0.914721422	4.74E-49
THYM	Epifactor	MRPS15	INO80E	0.918714457	3.01E-50
THYM	Epifactor	MRPS15	BRMS1	0.920028404	1.18E-50
THYM	Epifactor	MRPS15	TAF10	0.941570374	1.49E-58
THYM	Epifactor	MRPS15	ZNHIT1	0.941710858	1.30E-58
THYM	IUPHAR	MRPS15	FKBP1A	0.805963526	4.25E-29
THYM	IUPHAR	MRPS15	NT5M	0.806720865	3.45E-29
THYM	IUPHAR	MRPS15	HMOX2	0.807294302	2.94E-29
THYM	IUPHAR	MRPS15	MAP2K2	0.808706871	1.98E-29
THYM	IUPHAR	MRPS15	SLC39A3	0.80964048	1.52E-29
THYM	IUPHAR	MRPS15	PRMT7	0.811541439	8.83E-30
THYM	IUPHAR	MRPS15	ADCK5	0.811695302	8.45E-30
THYM	IUPHAR	MRPS15	PRMT1	0.814665974	3.58E-30
THYM	IUPHAR	MRPS15	SMPD2	0.819768831	7.88E-31
THYM	IUPHAR	MRPS15	ATG4B	0.824525391	1.84E-31
THYM	IUPHAR	MRPS15	DGAT1	0.825501081	1.36E-31
THYM	IUPHAR	MRPS15	DYRK4	0.843654513	3.31E-34
THYM	IUPHAR	MRPS15	CDK5	0.852004578	1.60E-35
THYM	IUPHAR	MRPS15	MVD	0.852152047	1.51E-35
THYM	IUPHAR	MRPS15	MMP24	0.862409529	2.78E-37
THYM	IUPHAR	MRPS15	PSMB6	0.86475665	1.07E-37
THYM	IUPHAR	MRPS15	SLC27A5	0.864997879	9.65E-38
THYM	IUPHAR	MRPS15	PSMB1	0.87098094	7.65E-39
THYM	IUPHAR	MRPS15	PPIA	0.905101638	2.16E-46
THYM	IUPHAR	MRPS15	PHKG2	0.911929384	3.01E-48
THYM	IUPHAR	MRPS15	SIRT6	0.914721422	4.74E-49
THYM	Kinase	MRPS15	MAP2K2	0.808706871	1.98E-29
THYM	Kinase	MRPS15	ADCK5	0.811695302	8.45E-30
THYM	Kinase	MRPS15	FASTK	0.812770141	6.20E-30
THYM	Kinase	MRPS15	DYRK4	0.843654513	3.31E-34
THYM	Kinase	MRPS15	CDK5	0.852004578	1.60E-35
THYM	Kinase	MRPS15	PHKG2	0.911929384	3.01E-48
THYM	TF	MRPS15	MYPOP	0.801727659	1.36E-28
THYM	TF	MRPS15	PIN1	0.803040146	9.50E-29
THYM	TF	MRPS15	CXXC1	0.807686966	2.63E-29
THYM	TF	MRPS15	MBD3	0.818610153	1.12E-30
THYM	TF	MRPS15	DNTTIP1	0.822300696	3.66E-31
THYM	TF	MRPS15	IRF3	0.822770259	3.17E-31
THYM	TF	MRPS15	THAP8	0.823268687	2.72E-31
THYM	TF	MRPS15	ETV2	0.823330447	2.67E-31
THYM	TF	MRPS15	USF1	0.82578766	1.24E-31
THYM	TF	MRPS15	THAP3	0.831666183	1.91E-32
THYM	TF	MRPS15	HMG20B	0.831993734	1.72E-32
THYM	TF	MRPS15	THAP7	0.833371825	1.09E-32
THYM	TF	MRPS15	GTF3A	0.853899275	7.82E-36
THYM	TF	MRPS15	ZNF668	0.859035989	1.07E-36
THYM	TF	MRPS15	ZGPAT	0.859259787	9.81E-37
THYM	TF	MRPS15	ZNF511	0.863279681	1.95E-37
THYM	TF	MRPS15	RBCK1	0.864635658	1.12E-37
THYM	TF	MRPS15	ZNF32	0.864720696	1.08E-37
THYM	TF	MRPS15	GLI4	0.867371615	3.58E-38
THYM	TF	MRPS15	ZNF444	0.868392597	2.33E-38
THYM	TF	MRPS15	THYN1	0.874996826	1.30E-39
THYM	TF	MRPS15	ZNF428	0.886409991	5.91E-42
THYM	TF	MRPS15	ZNF688	0.896673885	2.75E-44
THYM	TF	MRPS15	ZNF787	0.900602417	3.03E-45
THYM	TF	MRPS15	DRAP1	0.922733656	1.62E-51
THYM	TSG	MRPS15	PIN1	0.803040146	9.50E-29
THYM	TSG	MRPS15	NME1	0.816158633	2.31E-30
THYM	TSG	MRPS15	AIP	0.817680354	1.47E-30
THYM	TSG	MRPS15	IRF3	0.822770259	3.17E-31
THYM	TSG	MRPS15	PFN1	0.841483719	7.07E-34
THYM	TSG	MRPS15	GABARAP	0.843009818	4.15E-34
THYM	TSG	MRPS15	MAD1L1	0.844228806	2.70E-34
THYM	TSG	MRPS15	ST20	0.844278148	2.66E-34
THYM	TSG	MRPS15	GNB2L1	0.84464096	2.33E-34
THYM	TSG	MRPS15	GLTSCR2	0.846659035	1.14E-34
THYM	TSG	MRPS15	TSSC4	0.856098777	3.37E-36
THYM	TSG	MRPS15	ZNF668	0.859035989	1.07E-36
THYM	TSG	MRPS15	HTRA2	0.869044753	1.76E-38
THYM	TSG	MRPS15	NPRL2	0.882629272	3.75E-41
THYM	TSG	MRPS15	PARK7	0.898188907	1.19E-44
THYM	TSG	MRPS15	SIRT6	0.914721422	4.74E-49
THYM	TSG	MRPS15	BRMS1	0.920028404	1.18E-50
THYM	TSG	MRPS15	GADD45GIP1	0.925289799	2.33E-52
UCS	Cell metabolism gene	MRPS15	GMPPA	0.80437988	6.58E-29
UCS	Cell metabolism gene	MRPS15	DHRS4	0.805601696	4.70E-29
UCS	Cell metabolism gene	MRPS15	NT5M	0.806720865	3.45E-29
UCS	Cell metabolism gene	MRPS15	HMOX2	0.807294302	2.94E-29
UCS	Cell metabolism gene	MRPS15	TOMM5	0.809520038	1.57E-29
UCS	Cell metabolism gene	MRPS15	SNRPE	0.80956285	1.55E-29
UCS	Cell metabolism gene	MRPS15	PMPCA	0.810470192	1.20E-29
UCS	Cell metabolism gene	MRPS15	DHRS4L2	0.815076012	3.18E-30
UCS	Cell metabolism gene	MRPS15	NME1	0.816158633	2.31E-30
UCS	Cell metabolism gene	MRPS15	MED27	0.817292805	1.65E-30
UCS	Cell metabolism gene	MRPS15	PPCDC	0.819000929	9.93E-31
UCS	Cell metabolism gene	MRPS15	SMPD2	0.819768831	7.88E-31
UCS	Cell metabolism gene	MRPS15	PCYT2	0.821498671	4.67E-31
UCS	Cell metabolism gene	MRPS15	MIF	0.821874791	4.16E-31
UCS	Cell metabolism gene	MRPS15	TSTA3	0.823778498	2.32E-31
UCS	Cell metabolism gene	MRPS15	DGAT1	0.825501081	1.36E-31
UCS	Cell metabolism gene	MRPS15	POLD2	0.8260538	1.14E-31
UCS	Cell metabolism gene	MRPS15	TAZ	0.826395666	1.03E-31
UCS	Cell metabolism gene	MRPS15	GALK1	0.826743159	9.22E-32
UCS	Cell metabolism gene	MRPS15	APOA1	0.827503503	7.25E-32
UCS	Cell metabolism gene	MRPS15	HMBS	0.828005693	6.18E-32
UCS	Cell metabolism gene	MRPS15	COX17	0.828027482	6.14E-32
UCS	Cell metabolism gene	MRPS15	PFDN4	0.828823714	4.77E-32
UCS	Cell metabolism gene	MRPS15	FPGS	0.828865026	4.71E-32
UCS	Cell metabolism gene	MRPS15	ATP5G1	0.829419724	3.94E-32
UCS	Cell metabolism gene	MRPS15	LSM3	0.830760106	2.56E-32
UCS	Cell metabolism gene	MRPS15	SNRPD1	0.835392769	5.61E-33
UCS	Cell metabolism gene	MRPS15	IDH3G	0.835660223	5.13E-33
UCS	Cell metabolism gene	MRPS15	PSMB4	0.837159749	3.10E-33
UCS	Cell metabolism gene	MRPS15	GSS	0.837548499	2.72E-33
UCS	Cell metabolism gene	MRPS15	SNRPB	0.838296617	2.11E-33
UCS	Cell metabolism gene	MRPS15	PSMC5	0.838681869	1.85E-33
UCS	Cell metabolism gene	MRPS15	TOMM22	0.844118291	2.81E-34
UCS	Cell metabolism gene	MRPS15	DTYMK	0.845304499	1.84E-34
UCS	Cell metabolism gene	MRPS15	SRM	0.846906766	1.04E-34
UCS	Cell metabolism gene	MRPS15	SEC61G	0.848371446	6.11E-35
UCS	Cell metabolism gene	MRPS15	GEMIN7	0.849100089	4.68E-35
UCS	Cell metabolism gene	MRPS15	PFDN5	0.850607945	2.68E-35
UCS	Cell metabolism gene	MRPS15	MVD	0.852152047	1.51E-35
UCS	Cell metabolism gene	MRPS15	NANS	0.852332959	1.41E-35
UCS	Cell metabolism gene	MRPS15	EXOSC5	0.855909896	3.62E-36
UCS	Cell metabolism gene	MRPS15	TXN	0.857077165	2.31E-36
UCS	Cell metabolism gene	MRPS15	DPM2	0.858387921	1.38E-36
UCS	Cell metabolism gene	MRPS15	LSM5	0.858607602	1.27E-36
UCS	Cell metabolism gene	MRPS15	UROS	0.859160824	1.02E-36
UCS	Cell metabolism gene	MRPS15	PSME2	0.860653277	5.64E-37
UCS	Cell metabolism gene	MRPS15	POLR2F	0.862272781	2.94E-37
UCS	Cell metabolism gene	MRPS15	LSM2	0.863081818	2.12E-37
UCS	Cell metabolism gene	MRPS15	EXOSC4	0.864316231	1.28E-37
UCS	Cell metabolism gene	MRPS15	SNRPD3	0.864420277	1.22E-37
UCS	Cell metabolism gene	MRPS15	PSMB6	0.86475665	1.07E-37
UCS	Cell metabolism gene	MRPS15	SLC27A5	0.864997879	9.65E-38
UCS	Cell metabolism gene	MRPS15	SEC61B	0.865039414	9.48E-38
UCS	Cell metabolism gene	MRPS15	TIMM10	0.865103678	9.23E-38
UCS	Cell metabolism gene	MRPS15	TBCB	0.866930922	4.31E-38
UCS	Cell metabolism gene	MRPS15	UROD	0.868168174	2.56E-38
UCS	Cell metabolism gene	MRPS15	PGP	0.869126319	1.70E-38
UCS	Cell metabolism gene	MRPS15	MTX1	0.870473518	9.53E-39
UCS	Cell metabolism gene	MRPS15	PSMB1	0.87098094	7.65E-39
UCS	Cell metabolism gene	MRPS15	HSD17B10	0.872852092	3.37E-39
UCS	Cell metabolism gene	MRPS15	PSMD4	0.874442358	1.67E-39
UCS	Cell metabolism gene	MRPS15	PSMC1	0.876495767	6.60E-40
UCS	Cell metabolism gene	MRPS15	ITPA	0.877147065	4.90E-40
UCS	Cell metabolism gene	MRPS15	GEMIN6	0.88019023	1.20E-40
UCS	Cell metabolism gene	MRPS15	EXOSC1	0.880960295	8.31E-41
UCS	Cell metabolism gene	MRPS15	DPM3	0.88229169	4.41E-41
UCS	Cell metabolism gene	MRPS15	PSMA4	0.883001735	3.14E-41
UCS	Cell metabolism gene	MRPS15	PAFAH1B3	0.884765538	1.33E-41
UCS	Cell metabolism gene	MRPS15	WBSCR22	0.885475155	9.39E-42
UCS	Cell metabolism gene	MRPS15	FAU	0.885527216	9.15E-42
UCS	Cell metabolism gene	MRPS15	SNRPF	0.886185557	6.60E-42
UCS	Cell metabolism gene	MRPS15	GUK1	0.888134694	2.49E-42
UCS	Cell metabolism gene	MRPS15	PSMD13	0.888856994	1.72E-42
UCS	Cell metabolism gene	MRPS15	TIMM17B	0.889414732	1.30E-42
UCS	Cell metabolism gene	MRPS15	PFDN6	0.891307359	4.88E-43
UCS	Cell metabolism gene	MRPS15	POLR2H	0.895818929	4.40E-44
UCS	Cell metabolism gene	MRPS15	DGUOK	0.896525604	2.99E-44
UCS	Cell metabolism gene	MRPS15	TIMM13	0.89928972	6.41E-45
UCS	Cell metabolism gene	MRPS15	PSMC3	0.901240196	2.10E-45
UCS	Cell metabolism gene	MRPS15	PSMB10	0.903357393	6.11E-46
UCS	Cell metabolism gene	MRPS15	EBP	0.904562218	2.99E-46
UCS	Cell metabolism gene	MRPS15	PGLS	0.905716399	1.49E-46
UCS	Cell metabolism gene	MRPS15	ACOT8	0.906086253	1.19E-46
UCS	Cell metabolism gene	MRPS15	LSM4	0.907440676	5.19E-47
UCS	Cell metabolism gene	MRPS15	PHKG2	0.911929384	3.01E-48
UCS	Cell metabolism gene	MRPS15	PSMB7	0.916279753	1.64E-49
UCS	Cell metabolism gene	MRPS15	TOMM40	0.917980388	5.05E-50
UCS	Cell metabolism gene	MRPS15	POLR2J	0.920612704	7.73E-51
UCS	Cell metabolism gene	MRPS15	POLR2I	0.924125484	5.69E-52
UCS	Cell metabolism gene	MRPS15	APRT	0.930426283	3.79E-54
UCS	Cell metabolism gene	MRPS15	SNRPD2	0.93270651	5.49E-55
UCS	Cell metabolism gene	MRPS15	TIMM8B	0.933367025	3.10E-55
UCS	Cell metabolism gene	MRPS15	TIMM50	0.938317041	3.50E-57
UCS	Cell metabolism gene	MRPS15	PSMB3	0.940189072	5.82E-58
UCS	CGC	MRPS15	MAP2K2	0.808706871	1.98E-29
UCS	CGC	MRPS15	RBM10	0.835701737	5.06E-33
UCS	CGC	MRPS15	MGMT	0.852675649	1.24E-35
UCS	CGC	MRPS15	SDHAF2	0.855565044	4.14E-36
UCS	CGC	MRPS15	COX6C	0.887826599	2.91E-42
UCS	CGC	MRPS15	TFPT	0.889474326	1.26E-42
UCS	Epifactor	MRPS15	HIST1H2AJ	0.801775042	1.34E-28
UCS	Epifactor	MRPS15	HIST1H4J	0.803019879	9.55E-29
UCS	Epifactor	MRPS15	CXXC1	0.807686966	2.63E-29
UCS	Epifactor	MRPS15	PPM1G	0.810256184	1.27E-29
UCS	Epifactor	MRPS15	PRMT7	0.811541439	8.83E-30
UCS	Epifactor	MRPS15	PRMT1	0.814665974	3.58E-30
UCS	Epifactor	MRPS15	DMAP1	0.817298896	1.65E-30
UCS	Epifactor	MRPS15	MBD3	0.818610153	1.12E-30
UCS	Epifactor	MRPS15	ACTR5	0.820217728	6.89E-31
UCS	Epifactor	MRPS15	NOC2L	0.824440382	1.89E-31
UCS	Epifactor	MRPS15	RBX1	0.83158849	1.96E-32
UCS	Epifactor	MRPS15	HMG20B	0.831993734	1.72E-32
UCS	Epifactor	MRPS15	LAS1L	0.836629297	3.71E-33
UCS	Epifactor	MRPS15	PAF1	0.839371046	1.46E-33
UCS	Epifactor	MRPS15	SS18L2	0.843080161	4.05E-34
UCS	Epifactor	MRPS15	FBL	0.844461041	2.49E-34
UCS	Epifactor	MRPS15	HIST2H2AC	0.850759586	2.54E-35
UCS	Epifactor	MRPS15	C17orf49	0.851755295	1.75E-35
UCS	Epifactor	MRPS15	CDK5	0.852004578	1.60E-35
UCS	Epifactor	MRPS15	EXOSC5	0.855909896	3.62E-36
UCS	Epifactor	MRPS15	ZGPAT	0.859259787	9.81E-37
UCS	Epifactor	MRPS15	EXOSC4	0.864316231	1.28E-37
UCS	Epifactor	MRPS15	CCDC101	0.880219736	1.18E-40
UCS	Epifactor	MRPS15	EXOSC1	0.880960295	8.31E-41
UCS	Epifactor	MRPS15	PPP4C	0.887651147	3.17E-42
UCS	Epifactor	MRPS15	TFPT	0.889474326	1.26E-42
UCS	Epifactor	MRPS15	RUVBL2	0.901732395	1.58E-45
UCS	Epifactor	MRPS15	PRPF31	0.910750349	6.46E-48
UCS	Epifactor	MRPS15	SIRT6	0.914721422	4.74E-49
UCS	Epifactor	MRPS15	INO80E	0.918714457	3.01E-50
UCS	Epifactor	MRPS15	BRMS1	0.920028404	1.18E-50
UCS	Epifactor	MRPS15	TAF10	0.941570374	1.49E-58
UCS	Epifactor	MRPS15	ZNHIT1	0.941710858	1.30E-58
UCS	IUPHAR	MRPS15	FKBP1A	0.805963526	4.25E-29
UCS	IUPHAR	MRPS15	NT5M	0.806720865	3.45E-29
UCS	IUPHAR	MRPS15	HMOX2	0.807294302	2.94E-29
UCS	IUPHAR	MRPS15	MAP2K2	0.808706871	1.98E-29
UCS	IUPHAR	MRPS15	SLC39A3	0.80964048	1.52E-29
UCS	IUPHAR	MRPS15	PRMT7	0.811541439	8.83E-30
UCS	IUPHAR	MRPS15	ADCK5	0.811695302	8.45E-30
UCS	IUPHAR	MRPS15	PRMT1	0.814665974	3.58E-30
UCS	IUPHAR	MRPS15	SMPD2	0.819768831	7.88E-31
UCS	IUPHAR	MRPS15	ATG4B	0.824525391	1.84E-31
UCS	IUPHAR	MRPS15	DGAT1	0.825501081	1.36E-31
UCS	IUPHAR	MRPS15	DYRK4	0.843654513	3.31E-34
UCS	IUPHAR	MRPS15	CDK5	0.852004578	1.60E-35
UCS	IUPHAR	MRPS15	MVD	0.852152047	1.51E-35
UCS	IUPHAR	MRPS15	MMP24	0.862409529	2.78E-37
UCS	IUPHAR	MRPS15	PSMB6	0.86475665	1.07E-37
UCS	IUPHAR	MRPS15	SLC27A5	0.864997879	9.65E-38
UCS	IUPHAR	MRPS15	PSMB1	0.87098094	7.65E-39
UCS	IUPHAR	MRPS15	PPIA	0.905101638	2.16E-46
UCS	IUPHAR	MRPS15	PHKG2	0.911929384	3.01E-48
UCS	IUPHAR	MRPS15	SIRT6	0.914721422	4.74E-49
UCS	Kinase	MRPS15	MAP2K2	0.808706871	1.98E-29
UCS	Kinase	MRPS15	ADCK5	0.811695302	8.45E-30
UCS	Kinase	MRPS15	FASTK	0.812770141	6.20E-30
UCS	Kinase	MRPS15	DYRK4	0.843654513	3.31E-34
UCS	Kinase	MRPS15	CDK5	0.852004578	1.60E-35
UCS	Kinase	MRPS15	PHKG2	0.911929384	3.01E-48
UCS	TF	MRPS15	MYPOP	0.801727659	1.36E-28
UCS	TF	MRPS15	PIN1	0.803040146	9.50E-29
UCS	TF	MRPS15	CXXC1	0.807686966	2.63E-29
UCS	TF	MRPS15	MBD3	0.818610153	1.12E-30
UCS	TF	MRPS15	DNTTIP1	0.822300696	3.66E-31
UCS	TF	MRPS15	IRF3	0.822770259	3.17E-31
UCS	TF	MRPS15	THAP8	0.823268687	2.72E-31
UCS	TF	MRPS15	ETV2	0.823330447	2.67E-31
UCS	TF	MRPS15	USF1	0.82578766	1.24E-31
UCS	TF	MRPS15	THAP3	0.831666183	1.91E-32
UCS	TF	MRPS15	HMG20B	0.831993734	1.72E-32
UCS	TF	MRPS15	THAP7	0.833371825	1.09E-32
UCS	TF	MRPS15	GTF3A	0.853899275	7.82E-36
UCS	TF	MRPS15	ZNF668	0.859035989	1.07E-36
UCS	TF	MRPS15	ZGPAT	0.859259787	9.81E-37
UCS	TF	MRPS15	ZNF511	0.863279681	1.95E-37
UCS	TF	MRPS15	RBCK1	0.864635658	1.12E-37
UCS	TF	MRPS15	ZNF32	0.864720696	1.08E-37
UCS	TF	MRPS15	GLI4	0.867371615	3.58E-38
UCS	TF	MRPS15	ZNF444	0.868392597	2.33E-38
UCS	TF	MRPS15	THYN1	0.874996826	1.30E-39
UCS	TF	MRPS15	ZNF428	0.886409991	5.91E-42
UCS	TF	MRPS15	ZNF688	0.896673885	2.75E-44
UCS	TF	MRPS15	ZNF787	0.900602417	3.03E-45
UCS	TF	MRPS15	DRAP1	0.922733656	1.62E-51
UCS	TSG	MRPS15	PIN1	0.803040146	9.50E-29
UCS	TSG	MRPS15	NME1	0.816158633	2.31E-30
UCS	TSG	MRPS15	AIP	0.817680354	1.47E-30
UCS	TSG	MRPS15	IRF3	0.822770259	3.17E-31
UCS	TSG	MRPS15	PFN1	0.841483719	7.07E-34
UCS	TSG	MRPS15	GABARAP	0.843009818	4.15E-34
UCS	TSG	MRPS15	MAD1L1	0.844228806	2.70E-34
UCS	TSG	MRPS15	ST20	0.844278148	2.66E-34
UCS	TSG	MRPS15	GNB2L1	0.84464096	2.33E-34
UCS	TSG	MRPS15	GLTSCR2	0.846659035	1.14E-34
UCS	TSG	MRPS15	TSSC4	0.856098777	3.37E-36
UCS	TSG	MRPS15	ZNF668	0.859035989	1.07E-36
UCS	TSG	MRPS15	HTRA2	0.869044753	1.76E-38
UCS	TSG	MRPS15	NPRL2	0.882629272	3.75E-41
UCS	TSG	MRPS15	PARK7	0.898188907	1.19E-44
UCS	TSG	MRPS15	SIRT6	0.914721422	4.74E-49
UCS	TSG	MRPS15	BRMS1	0.920028404	1.18E-50
UCS	TSG	MRPS15	GADD45GIP1	0.925289799	2.33E-52
UVM	TSG	MRPS15	PARK7	0.862852595	8.02E-25

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KICH	MRPS15	MRPS5	1.25108287838437	0.000249803066253662
LIHC	MRPS15	MRPS7	1.27029395477208	0.00182077236082954
STAD	MRPS15	MRPS16	-1.64208084987431	0.00239070039242506
PRAD	MRPS15	MRPS9	1.04379115553269	0.00496210155254694
HNSC	MRPS15	MRPS16	-2.01564621821803	0.00518989327406416
CHOL	MRPS15	MRPS6	2.57097392409939	0.0078125
KICH	MRPS15	MRPS2	1.26543989555015	0.0114533305168152
LUSC	MRPS15	MRPS6	-1.26158810839259	0.013873001943322
ESCA	MRPS15	MRPS5	-2.15440118747854	0.0185546875
ESCA	MRPS15	MRPS2	-3.20556788084675	0.0244140625
THCA	MRPS15	MRPS10	1.33413691764991	1.55171507174296e-05
LUAD	MRPS15	MRPS5	-2.20881945885927	1.77904381378076e-06
LUSC	MRPS15	MRPS9	-3.60637641031661	1.82498668910368e-07
LUSC	MRPS15	MRPS2	-2.70930846488508	1.92864354932136e-09
KICH	MRPS15	MRPS35	1.14233082673341	1.96695327758789e-06
LUAD	MRPS15	MRPS9	-1.32894454884901	1.98978698949574e-05
PRAD	MRPS15	MRPS6	1.00673230965164	3.48152859299693e-07
KIRC	MRPS15	MRPS35	-2.33452405563859	3.58581186640388e-10
LUAD	MRPS15	MRPS14	-3.02634914022647	4.24616078981701e-06
LIHC	MRPS15	MRPS2	-1.14771055358828	4.2584580238307e-05
LUSC	MRPS15	MRPS5	-7.65956389962319	4.27210217182982e-06
KIRC	MRPS15	MRPS6	-3.12621933743663	4.95376546353503e-10
LUSC	MRPS15	MRPS14	-3.86726163364221	6.1453992201761e-05
KICH	MRPS15	MRPS6	-1.34376231922276	7.49826431274414e-05
BRCA	MRPS15	MRPS7	-2.12787460270434	9.33194208595055e-10

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with MRPS15

ICT1, CUL3, COPS5, CAND1, PTCD3, ESR2, PARK2, GRSF1, TRA2A, TRMT10B, MRPS31, MRPS5, HNRNPA1, ACSL4, HNRNPU, MPP1, ORC1, PHF8, VPS16, CDC73, Nfyc, Pcgf1, Prmt6, Brwd3, POU5F1, COQ2, COQ4, CDC14B, DUSP11, MRPS11, MRPS9, MCRS1, MRPS34, MRPS7, MRPS21, MRPS2, MRPS33, MRPS24, MRPS10, MRPS26, DAP3, MRPS27, NOA1, PRKACB, MRPS23, MRPS14, MRPS35, MRPS25, MRPS6, PRKAR1B, MRPS28, ZNF579, MCAT, MRPS22, STRBP, PRKACG, BMP4, HEXIM1, MEPCE, LARP7, RECQL4, HABP4, SERBP1, MB21D1, MYC, RPS6, HSPD1, AURKAIP1, TCF7L2, ALYREF, P2RY6, SNRNP70, Dppa3, TRIM28, CUL7, PLEKHA4, PTPRR, SRC, EXOC8, REXO1L1P, HIST1H1A, ORF8, C6orf203, METTL17, MRPL11, MTIF2, ORF4a, CLPP, MAFB, JMJD4, COX8A, PDHA1, FZR1, MRPS18C, RPS9, MRPS17, PRR3, H1FNT, RPL19, CBX6, SRSF3, MRPS18B, ZNF460, RPL6, ZKSCAN8, ZFC3H1, ABT1, RPL10, SRSF7, RBMS2, LIN28A, PRKRIR, ERAL1, MRPS16, HIST1H2AM, RPS8, ZNF574, SRSF1, GNL2, CTCF, MRPS12, ZC3H3, Rbm14, RCHY1, KLF12, LHX1, LHX2, KLF15, KLF4,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
MRPS15	ESCA	chr1	36923529	36923529	G	A	Nonsense_Mutation	p.R147*	4
MRPS15	BRCA	chr1	36921913	36921913	G	A	Missense_Mutation	p.R171C	4
MRPS15	KIRP	chr1	36921882	36921882	A	G	Missense_Mutation	p.I181T	3
MRPS15	LIHC	chr1	36923570	36923570	G	C	Missense_Mutation		3
MRPS15	LIHC	chr1	36923570	36923570	G	C	Missense_Mutation	p.S133C	3
MRPS15	PAAD	chr1	36921477	36921477	G	T	Missense_Mutation	p.A229D	3
MRPS15	STAD	chr1	36923582	36923582	A	C	Missense_Mutation		2
MRPS15	THYM	chr1	36921795	36921795	C	T	Missense_Mutation		2
MRPS15	ESCA	chr1	36923529	36923529	G	A	Nonsense_Mutation		2
MRPS15	KIRP	chr1	36926375	36926375	C	A	Missense_Mutation		2
MRPS15	STAD	chr1	36929865	36929865	G	A	Silent	p.V4V	2
MRPS15	STAD	chr1	36921446	36921446	C	G	Silent	p.R239R	2
MRPS15	BLCA	chr1	36927747	36927747	C	T	Missense_Mutation	p.D65N	2
MRPS15	HNSC	chr1	36929441	36929441	G	C	Silent	p.L47L	2
MRPS15	UCEC	chr1	36921490	36921490	T	G	Silent	p.R225	2
MRPS15	PAAD	chr1	36921477	36921477	G	T	Missense_Mutation		2
MRPS15	HNSC	chr1	36921846	36921846	G	-	Frame_Shift_Del	p.P193fs	2
MRPS15	STAD	chr1	36929762	36929762	C	A	Missense_Mutation	p.G39C	2
MRPS15	CESC	chr1	36926863	36926863	A	C	Splice_Site		2
MRPS15	UCEC	chr1	36923545	36923545	T	C	Silent	p.E141	2
MRPS15	HNSC	chr1	36921787	36921787	C	G	Splice_Site		2
MRPS15	STAD	chr1	36926331	36926331	A	C	Missense_Mutation	p.V116G	2
MRPS15	LIHC	chr1	36921872	36921872	C	-	Frame_Shift_Del	p.G184fs	2
MRPS15	UCEC	chr1	36927691	36927691	C	A	Missense_Mutation	p.E83D	2
MRPS15	SKCM	chr1	36921790	36921790	G	A	Missense_Mutation	p.R212W	2
MRPS15	STAD	chr1	36926911	36926911	A	G	Missense_Mutation	p.V85A	2
MRPS15	SKCM	chr1	36926372	36926372	C	T	Silent	p.E102E	2
MRPS15	KIRC	chr1	36926350	36926350	G	A	Nonsense_Mutation	p.Q110*	1
MRPS15	STAD	chr1	36921447	36921447	C	T	Missense_Mutation	p.R239Q	1
MRPS15	LUAD	chr1	36923551	36923551	A	T	Nonsense_Mutation	p.Y139*	1
MRPS15	HNSC	chr1	36921903	36921903	T	G	Missense_Mutation	p.N174T	1
MRPS15	SKCM	chr1	36927753	36927753	G	A	Silent	p.L63L	1
MRPS15	STAD	chr1	36921835	36921835	G	A	Nonsense_Mutation	p.R197*	1
MRPS15	THCA	chr1	36929799	36929799	C	A	Silent		1
MRPS15	ESCA	chr1	36923529	36923529	G	A	Nonsense_Mutation	p.R147X	1
MRPS15	LUAD	chr1	36926872	36926872	G	T	Missense_Mutation	p.A98D	1
MRPS15	HNSC	chr1	36926866	36926866	T	C	Splice_Site	p.K100_splice	1
MRPS15	KIRP	chr1	36921882	36921882	A	G	Missense_Mutation		1
MRPS15	LUAD	chr1	36926906	36926906	C	A	Missense_Mutation	p.D87Y	1
MRPS15	HNSC	chr1	36926325	36926325	T	C	Missense_Mutation	p.N118S	1
MRPS15	STAD	chr1	36923582	36923582	A	C	Missense_Mutation	p.I129S	1
MRPS15	THYM	chr1	36921795	36921795	C	T	Missense_Mutation	p.C210Y	1
MRPS15	HNSC	chr1	36926340	36926340	T	C	Missense_Mutation		1
MRPS15	LUAD	chr1	36926905	36926905	T	C	Missense_Mutation	p.D87G	1
MRPS15	HNSC	chr1	36926340	36926340	T	C	Missense_Mutation	p.K113R	1
MRPS15	BLCA	chr1	36927747	36927747	C	T	Missense_Mutation		1
MRPS15	KIRP	chr1	36926322	36926322	G	T	Missense_Mutation		1
MRPS15	UCEC	chr1	36921815	36921815	G	A	Silent	p.F203F	1
MRPS15	HNSC	chr1	36926866	36926866	T	C	Missense_Mutation		1
MRPS15	LUSC	chr1	36921956	36921956	C	T	Silent	p.L156L	1
MRPS15	HNSC	chr1	36929427	36929427	C	T	Missense_Mutation	p.G52E	1
MRPS15	LIHC	chr1	36926908	36926908	T	C	Missense_Mutation		1
MRPS15	UCEC	chr1	36923545	36923545	T	C	Silent	p.E141E	1
MRPS15	HNSC	chr1	36929427	36929427	C	T	Missense_Mutation		1
MRPS15	OV	chr1	36921912	36921912	C	T	Missense_Mutation	p.R171H	1
MRPS15	STAD	chr1	36921835	36921835	G	A	Nonsense_Mutation	p.R197X	1
MRPS15	HNSC	chr1	36929441	36929441	G	C	Silent		1
MRPS15	HNSC	chr1	36926866	36926866	T	C	Missense_Mutation	p.K100R	1
MRPS15	CESC	chr1	36929859	36929859	C	C	Missense_Mutation		1
MRPS15	HNSC	chr1	36926325	36926325	T	C	Missense_Mutation		1
MRPS15	HNSC	chr1	36921787	36921787	C	G	Splice_Site	p.R212_splice	1
MRPS15	COAD	chr1	36921820	36921820	G	A	Nonsense_Mutation	p.R202X	1
MRPS15	LIHC	chr1	36926872	36926872	G	A	Missense_Mutation		1
MRPS15	HNSC	chr1	36921903	36921903	T	G	Missense_Mutation		1
MRPS15	KIRC	chr1	36926350	36926350	G	A	Nonsense_Mutation	p.Q110X	1
MRPS15	STAD	chr1	36923582	36923582	A	C	Splice_Site	p.I129_splice	1
MRPS15	COAD	chr1	36921847	36921847	G	A	Missense_Mutation	p.P193S	1
MRPS15	LUAD	chr1	36926372	36926372	C	G	Missense_Mutation	p.E102D	1
MRPS15	HNSC	chr1	36921846	36921846	G	-	Frame_Shift_Del		1
MRPS15	SKCM	chr1	36921471	36921471	G	C	Missense_Mutation	p.A231G	1

Copy number variation (CNV) of MRPS15
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across MRPS15
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
101672	N/A	BQ649564	ALDH7A1	chr5	125918562	-	MRPS15	chr1	36921447	-
101672	STAD	TCGA-D7-6528	KIAA0907	chr1	155899086	-	MRPS15	chr1	36923582	-
78972	SKCM	TCGA-D3-A1Q8	MRPS15	chr1	36926292	-	HAT1	chr2	172782046	+
101672	Non-Cancer	43N	THRAP3	chr1	36690106	+	MRPS15	chr1	36923582	-
101673	N/A	EC578027	ZNF235	chr19	44794829	-	MRPS15	chr1	36923523	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
ACC	MRPS15	0.0184324287270271	0.52
LIHC	MRPS15	0.0224042038720204	0.6

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUAD	MRPS15	0.032580488696197	0.98
LUSC	MRPS15	0.0280861571516205	0.87
THCA	MRPS15	0.00947940254268552	0.3
SARC	MRPS15	0.00145761300376905	0.048

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source