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Center for Computational Systems Medicine
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Gene Summary

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Translation studies in PubMed

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Exon Skipping Events

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Expression

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Expression Regulation

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Associated Genes

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Protein 3D Structure

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Protein-Protein Interaction

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Mutations

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Prognostic Analysis

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Gender Association

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Age Association

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Related Drugs

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Related Diseases

Translation Factor: CAPRIN2 (NCBI Gene ID:65981)


Gene Summary

check button Gene Summary
Gene InformationGene Name: CAPRIN2
Gene ID: 65981
Gene Symbol

CAPRIN2

Gene ID

65981

Gene Namecaprin family member 2
SynonymsC1QDC1|EEG-1|EEG1|RNG140
Cytomap

12p11.21

Type of Geneprotein-coding
Descriptioncaprin-2C1q domain-containing protein 1RNA granule protein 140cytoplasmic activation/proliferation-associated protein 2gastric cancer multidrug resistance-associated protein
Modification date20200313
UniProtAcc

Q6IMN6


check button Child GO biological process term(s) under GO:0006412
GO IDGO term
GO:0017148Negative regulation of translation
GO:0006417Regulation of translation
GO:0006412Translation


check button Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCAPRIN2

GO:0030308

negative regulation of cell growth

14593112

HgeneCAPRIN2

GO:0032092

positive regulation of protein binding

18762581

HgeneCAPRIN2

GO:0033138

positive regulation of peptidyl-serine phosphorylation

18762581

HgeneCAPRIN2

GO:0045944

positive regulation of transcription by RNA polymerase II

18762581

HgeneCAPRIN2

GO:0090263

positive regulation of canonical Wnt signaling pathway

18762581



check button Inferred gene age of translation factor.
GeneInferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
CAPRIN2(355.7 - 733]


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Translation Studies in PubMed

check button We searched PubMed using 'CAPRIN2[title] AND translation [title] AND human.'
GeneTitlePMID
CAPRIN2..


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Exon Skipping Events

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.
all structure

check button Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ENSTExon skip start (DNA)Exon Skip end (DNA)ORF

check button Exon skipping position in the amino acid sequence.
ENSTExon skip start (DNA)Exon Skip end (DNA)Len(transcript seq)Exon skip start (mRNA)Exon Skip end (mRNA)Len(amino acid seq)Exon skip start (AA)Exon Skip end (AA)

check button Potentially (partially) lost protein functional features of UniProt.
UniProtAccExon skip start (AA)Exon Skip end (AA)Function feature start (AA)Function feature end (AA)Functional feature typeFunctional feature desc.


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Expression


check buttonGene expression level across TCGA pancancer
all structure

check buttonGene expression level across GTEx pantissue
all structure

check buttonExpression level of gene isoforms across TCGA pancancer
all structure

check buttonExpression level of gene isoforms across GTEx pantissue
all structure

check buttonCancer(tissue) type-specific expression level of Translation factor using z-score distriution
all structure

check buttonDifferential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)
all structure
Cancer typeTranslation factorFCadj.pval
KIRCCAPRIN21.493445726325150.000318337905201111
HNSCCAPRIN2-1.019107705370570.00186235073124408


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Expression Regulation


check buttonTranslation factor expression regulation through miRNA binding
Cancer typeGenemiRNATargetScan binding score (Context++ score percentile)CoefficientPvalue


check buttonTranslation factor expression regulation through methylation in the promoter of Translation factor
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a

check buttonTranslation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a

check buttonTranslation factor expression regulation through copy number variation of Translation factor
all structure
Cancer typeGeneCoefficientPvalue
SKCMCAPRIN20.0518997440.008633625

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Associated Genes


check button Strongly correlated genes belong to cellular important gene groups with CAPRIN2 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)
all structure
Cancer typeGene groupTranslation factorCorrelated geneCoefficientPvalue
UVMCell metabolism geneCAPRIN2NUP1070.8006115894.99E-19
UVMCell metabolism geneCAPRIN2GNPDA20.8013639164.37E-19
UVMCell metabolism geneCAPRIN2NUDT120.8014637384.29E-19
UVMCell metabolism geneCAPRIN2ALG10B0.8029108313.32E-19
UVMCell metabolism geneCAPRIN2MED170.8033895733.05E-19
UVMCell metabolism geneCAPRIN2TNPO10.8035891112.95E-19
UVMCell metabolism geneCAPRIN2SACM1L0.803705142.89E-19
UVMCell metabolism geneCAPRIN2PIKFYVE0.803979472.75E-19
UVMCell metabolism geneCAPRIN2PIK3R10.8043545842.57E-19
UVMCell metabolism geneCAPRIN2LPGAT10.8046601482.43E-19
UVMCell metabolism geneCAPRIN2PSMC60.8057386172.00E-19
UVMCell metabolism geneCAPRIN2L2HGDH0.8061489951.86E-19
UVMCell metabolism geneCAPRIN2ACADSB0.8068780771.63E-19
UVMCell metabolism geneCAPRIN2ALG130.8088564371.14E-19
UVMCell metabolism geneCAPRIN2PLA2G12A0.8106756058.12E-20
UVMCell metabolism geneCAPRIN2MED70.8107515858.01E-20
UVMCell metabolism geneCAPRIN2TRMT110.8113613497.15E-20
UVMCell metabolism geneCAPRIN2EDEM30.8121815856.13E-20
UVMCell metabolism geneCAPRIN2DCK0.812423845.86E-20
UVMCell metabolism geneCAPRIN2MTR0.8139048054.43E-20
UVMCell metabolism geneCAPRIN2CSGALNACT20.8187825481.74E-20
UVMCell metabolism geneCAPRIN2SMG10.8220200779.19E-21
UVMCell metabolism geneCAPRIN2PRKAG20.8227451197.95E-21
UVMCell metabolism geneCAPRIN2UGGT20.8228913627.72E-21
UVMCell metabolism geneCAPRIN2FBXL30.8246253695.45E-21
UVMCell metabolism geneCAPRIN2NAMPT0.8254355434.62E-21
UVMCell metabolism geneCAPRIN2NUPL10.8254704454.59E-21
UVMCell metabolism geneCAPRIN2COL4A3BP0.8261531843.99E-21
UVMCell metabolism geneCAPRIN2NUPL20.8289610922.24E-21
UVMCell metabolism geneCAPRIN2FBXW70.8291706042.14E-21
UVMCell metabolism geneCAPRIN2DBT0.82925432.11E-21
UVMCell metabolism geneCAPRIN2RANBP20.8294684322.02E-21
UVMCell metabolism geneCAPRIN2NUP500.8299439791.82E-21
UVMCell metabolism geneCAPRIN2MANEA0.8299674811.82E-21
UVMCell metabolism geneCAPRIN2XPO10.8343414737.18E-22
UVMCell metabolism geneCAPRIN2AGL0.836105654.90E-22
UVMCell metabolism geneCAPRIN2TRDMT10.8426014021.15E-22
UVMCell metabolism geneCAPRIN2PNPLA80.848607832.85E-23
UVMCell metabolism geneCAPRIN2AASS0.862943967.83E-25
UVMCell metabolism geneCAPRIN2FAR10.8785446249.56E-27
UVMCell metabolism geneCAPRIN2PRKAA10.8808597944.72E-27
UVMCell metabolism geneCAPRIN2GXYLT10.8817816943.55E-27
UVMCell metabolism geneCAPRIN2ETNK10.9130468494.10E-32
UVMCGCCAPRIN2ATRX0.8018042944.04E-19
UVMCGCCAPRIN2PIK3R10.8043545842.57E-19
UVMCGCCAPRIN2TRIP110.8047145532.41E-19
UVMCGCCAPRIN2CDC730.8050360862.27E-19
UVMCGCCAPRIN2ARID20.8071719251.55E-19
UVMCGCCAPRIN2PHF60.8076132361.43E-19
UVMCGCCAPRIN2PSIP10.8142935464.12E-20
UVMCGCCAPRIN2USP80.817754162.12E-20
UVMCGCCAPRIN2BCLAF10.817904832.06E-20
UVMCGCCAPRIN2FBXO110.8190478181.65E-20
UVMCGCCAPRIN2MAP3K10.8203031451.29E-20
UVMCGCCAPRIN2ITGAV0.8204926311.24E-20
UVMCGCCAPRIN2AKAP90.8207743981.18E-20
UVMCGCCAPRIN2ATM0.8230870517.42E-21
UVMCGCCAPRIN2STAG20.8243688245.74E-21
UVMCGCCAPRIN2TET20.8245360395.55E-21
UVMCGCCAPRIN2SS18L10.8250241565.03E-21
UVMCGCCAPRIN2KIF5B0.8283493472.54E-21
UVMCGCCAPRIN2JAK20.8284397832.50E-21
UVMCGCCAPRIN2EPS150.8287386122.35E-21
UVMCGCCAPRIN2FBXW70.8291706042.14E-21
UVMCGCCAPRIN2RANBP20.8294684322.02E-21
UVMCGCCAPRIN2BAZ1A0.8306152321.59E-21
UVMCGCCAPRIN2TRIM330.832811259.96E-22
UVMCGCCAPRIN2RGPD30.8338768157.93E-22
UVMCGCCAPRIN2XPO10.8343414737.18E-22
UVMCGCCAPRIN2MALT10.8352810515.86E-22
UVMCGCCAPRIN2KRAS0.8420872491.30E-22
UVMCGCCAPRIN2ARHGAP50.8436600939.05E-23
UVMCGCCAPRIN2GOPC0.846324134.88E-23
UVMCGCCAPRIN2SUZ120.8477363583.50E-23
UVMCGCCAPRIN2CREB10.8493151782.41E-23
UVMCGCCAPRIN2PWWP2A0.8525306641.11E-23
UVMCGCCAPRIN2ZMYM20.8531036459.62E-24
UVMCGCCAPRIN2RAD170.8544589136.88E-24
UVMCGCCAPRIN2DDX50.8686649891.66E-25
UVMCGCCAPRIN2KTN10.8788277018.78E-27
UVMCGCCAPRIN2SF3B10.8822086623.11E-27
UVMCGCCAPRIN2DICER10.8930020739.05E-29
UVMCGCCAPRIN2PMS10.9040647911.59E-30
UVMCGCCAPRIN2ETNK10.9130468494.10E-32
UVMEpifactorCAPRIN2MYSM10.8002547065.31E-19
UVMEpifactorCAPRIN2BRCC30.8006323534.97E-19
UVMEpifactorCAPRIN2ATRX0.8018042944.04E-19
UVMEpifactorCAPRIN2CHUK0.8035600492.96E-19
UVMEpifactorCAPRIN2CDC730.8050360862.27E-19
UVMEpifactorCAPRIN2RLIM0.805460722.11E-19
UVMEpifactorCAPRIN2MTF20.8055333192.08E-19
UVMEpifactorCAPRIN2ARID20.8071719251.55E-19
UVMEpifactorCAPRIN2SP1000.8076717161.41E-19
UVMEpifactorCAPRIN2TDG0.8082848821.26E-19
UVMEpifactorCAPRIN2CDK170.8093361641.04E-19
UVMEpifactorCAPRIN2PCGF60.8119364516.42E-20
UVMEpifactorCAPRIN2PSIP10.8142935464.12E-20
UVMEpifactorCAPRIN2YEATS40.8182242021.94E-20
UVMEpifactorCAPRIN2RCOR30.8191706871.61E-20
UVMEpifactorCAPRIN2CIR10.8200553951.35E-20
UVMEpifactorCAPRIN2HMGB10.8217842849.63E-21
UVMEpifactorCAPRIN2ZMYND110.8222616668.75E-21
UVMEpifactorCAPRIN2PRKAG20.8227451197.95E-21
UVMEpifactorCAPRIN2ATM0.8230870517.42E-21
UVMEpifactorCAPRIN2UHRF20.8244694715.62E-21
UVMEpifactorCAPRIN2TET20.8245360395.55E-21
UVMEpifactorCAPRIN2CHD10.8245975045.48E-21
UVMEpifactorCAPRIN2SS18L10.8250241565.03E-21
UVMEpifactorCAPRIN2TLK10.8274506613.06E-21
UVMEpifactorCAPRIN2JAK20.8284397832.50E-21
UVMEpifactorCAPRIN2BAZ1A0.8306152321.59E-21
UVMEpifactorCAPRIN2MAP3K70.8318466611.22E-21
UVMEpifactorCAPRIN2SMEK20.8321772241.14E-21
UVMEpifactorCAPRIN2TRIM330.832811259.96E-22
UVMEpifactorCAPRIN2EID10.8349386396.31E-22
UVMEpifactorCAPRIN2MBTD10.8382232333.08E-22
UVMEpifactorCAPRIN2CUL50.8389357162.63E-22
UVMEpifactorCAPRIN2RMI10.8396338532.25E-22
UVMEpifactorCAPRIN2ARID4B0.8412252611.57E-22
UVMEpifactorCAPRIN2HCFC20.845222216.31E-23
UVMEpifactorCAPRIN2CUL20.8468353934.33E-23
UVMEpifactorCAPRIN2SUZ120.8477363583.50E-23
UVMEpifactorCAPRIN2OGT0.8499624912.06E-23
UVMEpifactorCAPRIN2DNTTIP20.8520358421.25E-23
UVMEpifactorCAPRIN2ZMYM20.8531036459.62E-24
UVMEpifactorCAPRIN2PHIP0.8569155523.72E-24
UVMEpifactorCAPRIN2NIPBL0.859482991.93E-24
UVMEpifactorCAPRIN2CHD90.8649440524.59E-25
UVMEpifactorCAPRIN2SMEK10.8668684662.72E-25
UVMEpifactorCAPRIN2EPC20.870652429.53E-26
UVMEpifactorCAPRIN2ATAD2B0.8733382814.43E-26
UVMEpifactorCAPRIN2ARID4A0.8782170761.06E-26
UVMEpifactorCAPRIN2PRKAA10.8808597944.72E-27
UVMEpifactorCAPRIN2SF3B10.8822086623.11E-27
UVMEpifactorCAPRIN2INO80D0.884084091.73E-27
UVMEpifactorCAPRIN2BAZ2B0.8843365571.59E-27
UVMEpifactorCAPRIN2JMJD1C0.8846552481.44E-27
UVMEpifactorCAPRIN2BRWD10.8870570276.64E-28
UVMEpifactorCAPRIN2USP150.8934727277.69E-29
UVMIUPHARCAPRIN2ATP6V0A20.8017868564.06E-19
UVMIUPHARCAPRIN2CDKL30.803218883.15E-19
UVMIUPHARCAPRIN2CHUK0.8035600492.96E-19
UVMIUPHARCAPRIN2PIKFYVE0.803979472.75E-19
UVMIUPHARCAPRIN2PIK3R10.8043545842.57E-19
UVMIUPHARCAPRIN2CSNK1A10.8047246922.41E-19
UVMIUPHARCAPRIN2NIPA10.8053387842.15E-19
UVMIUPHARCAPRIN2RPS6KC10.8058027721.98E-19
UVMIUPHARCAPRIN2STK38L0.8063398351.80E-19
UVMIUPHARCAPRIN2DYRK1A0.8064541441.76E-19
UVMIUPHARCAPRIN2NR3C10.8065622131.73E-19
UVMIUPHARCAPRIN2IFNGR10.8074291331.48E-19
UVMIUPHARCAPRIN2SP1000.8076717161.41E-19
UVMIUPHARCAPRIN2SLC30A70.8076793951.41E-19
UVMIUPHARCAPRIN2CDK170.8093361641.04E-19
UVMIUPHARCAPRIN2MAP4K30.8094601711.02E-19
UVMIUPHARCAPRIN2BIRC20.8106377698.18E-20
UVMIUPHARCAPRIN2PLA2G12A0.8106756058.12E-20
UVMIUPHARCAPRIN2TAS2R200.8125780355.69E-20
UVMIUPHARCAPRIN2MTR0.8139048054.43E-20
UVMIUPHARCAPRIN2NEK70.8149473053.64E-20
UVMIUPHARCAPRIN2MAPK60.8152609933.43E-20
UVMIUPHARCAPRIN2FBXO110.8190478181.65E-20
UVMIUPHARCAPRIN2MAP3K10.8203031451.29E-20
UVMIUPHARCAPRIN2ITGAV0.8204926311.24E-20
UVMIUPHARCAPRIN2SMG10.8220200779.19E-21
UVMIUPHARCAPRIN2ZMYND110.8222616668.75E-21
UVMIUPHARCAPRIN2PRKAG20.8227451197.95E-21
UVMIUPHARCAPRIN2ATM0.8230870517.42E-21
UVMIUPHARCAPRIN2TLK10.8274506613.06E-21
UVMIUPHARCAPRIN2SENP70.8275704392.99E-21
UVMIUPHARCAPRIN2JAK20.8284397832.50E-21
UVMIUPHARCAPRIN2BAZ1A0.8306152321.59E-21
UVMIUPHARCAPRIN2SENP60.8309008071.49E-21
UVMIUPHARCAPRIN2MAP3K70.8318466611.22E-21
UVMIUPHARCAPRIN2TRIM330.832811259.96E-22
UVMIUPHARCAPRIN2ABCA50.8340108357.70E-22
UVMIUPHARCAPRIN2RIOK30.8343347977.19E-22
UVMIUPHARCAPRIN2XPO10.8343414737.18E-22
UVMIUPHARCAPRIN2MALT10.8352810515.86E-22
UVMIUPHARCAPRIN2PKN20.8370203824.01E-22
UVMIUPHARCAPRIN2MARK30.8396474172.24E-22
UVMIUPHARCAPRIN2SLC4A70.8414942971.48E-22
UVMIUPHARCAPRIN2IRAK40.8418434611.37E-22
UVMIUPHARCAPRIN2TBK10.8420216971.31E-22
UVMIUPHARCAPRIN2KRAS0.8420872491.30E-22
UVMIUPHARCAPRIN2ABCA100.8444435977.55E-23
UVMIUPHARCAPRIN2MAP3K20.8454178796.03E-23
UVMIUPHARCAPRIN2TRPC10.8460170745.24E-23
UVMIUPHARCAPRIN2CSNK1G30.8527063161.06E-23
UVMIUPHARCAPRIN2PHIP0.8569155523.72E-24
UVMIUPHARCAPRIN2NAPEPLD0.8578087982.97E-24
UVMIUPHARCAPRIN2NR2C10.8608185151.37E-24
UVMIUPHARCAPRIN2XIAP0.8642742715.49E-25
UVMIUPHARCAPRIN2ATAD2B0.8733382814.43E-26
UVMIUPHARCAPRIN2TRPM70.874457053.21E-26
UVMIUPHARCAPRIN2TNKS20.8801485675.87E-27
UVMIUPHARCAPRIN2PRKAA10.8808597944.72E-27
UVMIUPHARCAPRIN2BAZ2B0.8843365571.59E-27
UVMIUPHARCAPRIN2JMJD1C0.8846552481.44E-27
UVMIUPHARCAPRIN2BRWD10.8870570276.64E-28
UVMIUPHARCAPRIN2CLK10.8965031812.65E-29
UVMIUPHARCAPRIN2CLK40.902158573.30E-30
UVMKinaseCAPRIN2CDKL30.803218883.15E-19
UVMKinaseCAPRIN2CHUK0.8035600492.96E-19
UVMKinaseCAPRIN2CSNK1A10.8047246922.41E-19
UVMKinaseCAPRIN2RPS6KC10.8058027721.98E-19
UVMKinaseCAPRIN2STK38L0.8063398351.80E-19
UVMKinaseCAPRIN2DYRK1A0.8064541441.76E-19
UVMKinaseCAPRIN2CDK170.8093361641.04E-19
UVMKinaseCAPRIN2MAP4K30.8094601711.02E-19
UVMKinaseCAPRIN2NEK70.8149473053.64E-20
UVMKinaseCAPRIN2MAPK60.8152609933.43E-20
UVMKinaseCAPRIN2MAP3K10.8203031451.29E-20
UVMKinaseCAPRIN2SMG10.8220200779.19E-21
UVMKinaseCAPRIN2ATM0.8230870517.42E-21
UVMKinaseCAPRIN2COL4A3BP0.8261531843.99E-21
UVMKinaseCAPRIN2TLK10.8274506613.06E-21
UVMKinaseCAPRIN2JAK20.8284397832.50E-21
UVMKinaseCAPRIN2BAZ1A0.8306152321.59E-21
UVMKinaseCAPRIN2MAP3K70.8318466611.22E-21
UVMKinaseCAPRIN2TRIM330.832811259.96E-22
UVMKinaseCAPRIN2RIOK30.8343347977.19E-22
UVMKinaseCAPRIN2PKN20.8370203824.01E-22
UVMKinaseCAPRIN2PAN30.8385025852.89E-22
UVMKinaseCAPRIN2MARK30.8396474172.24E-22
UVMKinaseCAPRIN2IRAK40.8418434611.37E-22
UVMKinaseCAPRIN2TBK10.8420216971.31E-22
UVMKinaseCAPRIN2MAP3K20.8454178796.03E-23
UVMKinaseCAPRIN2CSNK1G30.8527063161.06E-23
UVMKinaseCAPRIN2TRPM70.874457053.21E-26
UVMKinaseCAPRIN2PRKAA10.8808597944.72E-27
UVMKinaseCAPRIN2CLK10.8965031812.65E-29
UVMKinaseCAPRIN2CLK40.902158573.30E-30
UVMTFCAPRIN2MYSM10.8002547065.31E-19
UVMTFCAPRIN2ZNF5700.800517635.07E-19
UVMTFCAPRIN2ZNF4610.8008741494.76E-19
UVMTFCAPRIN2PRDM100.8015951824.20E-19
UVMTFCAPRIN2ZNF5570.8019826563.92E-19
UVMTFCAPRIN2ZNF1010.8023145153.69E-19
UVMTFCAPRIN2ZNF8080.8026163823.50E-19
UVMTFCAPRIN2ZNF410.8026579223.48E-19
UVMTFCAPRIN2ZNF240.8033052223.10E-19
UVMTFCAPRIN2ZNF286A0.8040026362.74E-19
UVMTFCAPRIN2ZNF4700.8044711242.52E-19
UVMTFCAPRIN2ZNF5690.8045557932.48E-19
UVMTFCAPRIN2ZNF2660.8047408872.40E-19
UVMTFCAPRIN2RLF0.8048740682.34E-19
UVMTFCAPRIN2ZNF6250.8054713732.10E-19
UVMTFCAPRIN2MTF20.8055333192.08E-19
UVMTFCAPRIN2NFXL10.8059464161.93E-19
UVMTFCAPRIN2NR3C10.8065622131.73E-19
UVMTFCAPRIN2ARID20.8071719251.55E-19
UVMTFCAPRIN2SP1000.8076717161.41E-19
UVMTFCAPRIN2ZNF5640.8095531521.00E-19
UVMTFCAPRIN2ZBTB110.8101273688.99E-20
UVMTFCAPRIN2ZNF2300.8104125118.53E-20
UVMTFCAPRIN2ZNF3470.8106154788.21E-20
UVMTFCAPRIN2ZNF3830.811252627.30E-20
UVMTFCAPRIN2PCGF60.8119364516.42E-20
UVMTFCAPRIN2CEBPZ0.8123785725.91E-20
UVMTFCAPRIN2SP30.8132338015.03E-20
UVMTFCAPRIN2ZNF5460.8134347494.85E-20
UVMTFCAPRIN2MEF2A0.8134563584.83E-20
UVMTFCAPRIN2ZNF6800.8140943384.28E-20
UVMTFCAPRIN2ZNF2350.8142442524.16E-20
UVMTFCAPRIN2ZNF5660.8157269133.14E-20
UVMTFCAPRIN2LIN540.8178043412.10E-20
UVMTFCAPRIN2ZNF6240.8178724382.07E-20
UVMTFCAPRIN2SP40.8188041561.73E-20
UVMTFCAPRIN2ZNF2670.8188098251.73E-20
UVMTFCAPRIN2ZNF2220.8199327281.39E-20
UVMTFCAPRIN2ZBTB410.8201303441.33E-20
UVMTFCAPRIN2ZFP140.8228349477.81E-21
UVMTFCAPRIN2TET20.8245360395.55E-21
UVMTFCAPRIN2ZNF3200.8245517725.53E-21
UVMTFCAPRIN2ZNF4930.8246130935.46E-21
UVMTFCAPRIN2IKZF50.8266635033.60E-21
UVMTFCAPRIN2EEA10.8269706073.38E-21
UVMTFCAPRIN2ZNF1430.8284850562.47E-21
UVMTFCAPRIN2ZNF4510.8285485562.44E-21
UVMTFCAPRIN2ZNF1410.82930572.08E-21
UVMTFCAPRIN2ZNF280D0.8294307672.03E-21
UVMTFCAPRIN2ZNF2680.8297283121.91E-21
UVMTFCAPRIN2ZNF6550.8305589221.60E-21
UVMTFCAPRIN2FOXN20.8312985741.37E-21
UVMTFCAPRIN2ZNF2920.8317633261.24E-21
UVMTFCAPRIN2PURB0.8318562241.22E-21
UVMTFCAPRIN2ZNF585B0.8324907631.07E-21
UVMTFCAPRIN2ZNF4400.8327476961.01E-21
UVMTFCAPRIN2ZNF7010.8329578229.65E-22
UVMTFCAPRIN2AHCTF10.8345647856.84E-22
UVMTFCAPRIN2ZNF1000.8347545056.56E-22
UVMTFCAPRIN2ZNF75D0.8348811876.39E-22
UVMTFCAPRIN2ZNF1380.8358361235.19E-22
UVMTFCAPRIN2ZNF6060.8363678334.62E-22
UVMTFCAPRIN2ZNF6440.8366036584.39E-22
UVMTFCAPRIN2RBAK0.8367475994.26E-22
UVMTFCAPRIN2ZNF2600.8370985553.94E-22
UVMTFCAPRIN2ZNF8450.8371456083.90E-22
UVMTFCAPRIN2ZNF140.837899473.31E-22
UVMTFCAPRIN2ZNF7820.8391906132.48E-22
UVMTFCAPRIN2ZNF5580.8394234532.36E-22
UVMTFCAPRIN2ZNF2540.8395447262.29E-22
UVMTFCAPRIN2ZNF3020.841636851.43E-22
UVMTFCAPRIN2ZNF7610.8416998351.41E-22
UVMTFCAPRIN2ZNF6750.841886521.36E-22
UVMTFCAPRIN2THAP90.8421702131.27E-22
UVMTFCAPRIN2ZNF3260.842308621.23E-22
UVMTFCAPRIN2ZNF4320.8431974041.01E-22
UVMTFCAPRIN2ZNF4840.8474289923.77E-23
UVMTFCAPRIN2ZNF120.847859513.40E-23
UVMTFCAPRIN2ZNF4490.848654322.82E-23
UVMTFCAPRIN2CREB10.8493151782.41E-23
UVMTFCAPRIN2ZNF6110.8493354932.40E-23
UVMTFCAPRIN2THAP60.8500734152.01E-23
UVMTFCAPRIN2ZNF5270.8503548211.88E-23
UVMTFCAPRIN2ZNF37A0.8506378741.75E-23
UVMTFCAPRIN2ZNF33A0.8529168161.01E-23
UVMTFCAPRIN2THAP50.8548408876.26E-24
UVMTFCAPRIN2ZNF4800.8549951366.02E-24
UVMTFCAPRIN2ZNF280.8556560835.11E-24
UVMTFCAPRIN2ZNF5670.8559039454.80E-24
UVMTFCAPRIN2SMAD50.8559305954.77E-24
UVMTFCAPRIN2ZNF1800.8563144074.33E-24
UVMTFCAPRIN2ZNF1360.8563638774.28E-24
UVMTFCAPRIN2ZNF230.8566332254.00E-24
UVMTFCAPRIN2ZNF5290.8570443393.60E-24
UVMTFCAPRIN2ZNF8000.8577918462.98E-24
UVMTFCAPRIN2ZNF6580.858726182.35E-24
UVMTFCAPRIN2ZNF4300.8587925262.31E-24
UVMTFCAPRIN2NR2C10.8608185151.37E-24
UVMTFCAPRIN2ZNF1400.8614957511.15E-24
UVMTFCAPRIN2ZNF830.8620399389.93E-25
UVMTFCAPRIN2ZNF1600.8623180879.23E-25
UVMTFCAPRIN2ZMAT10.8624670648.88E-25
UVMTFCAPRIN2ZBED50.8631226487.46E-25
UVMTFCAPRIN2ZNF7990.8643065235.44E-25
UVMTFCAPRIN2ZNF6740.8654436534.01E-25
UVMTFCAPRIN2ZNF2260.8669816512.64E-25
UVMTFCAPRIN2ZNF430.8696173661.27E-25
UVMTFCAPRIN2ZNF1810.8706867659.44E-26
UVMTFCAPRIN2ZNF354B0.8711128818.37E-26
UVMTFCAPRIN2GPBP10.8716620617.16E-26
UVMTFCAPRIN2ZNF260.8717401337.01E-26
UVMTFCAPRIN2TMF10.8717432237.00E-26
UVMTFCAPRIN2ZNF840.8723911515.82E-26
UVMTFCAPRIN2ZNF1820.8738161393.86E-26
UVMTFCAPRIN2ZNF780A0.8740139833.65E-26
UVMTFCAPRIN2ZNF2240.8746174173.06E-26
UVMTFCAPRIN2ZBTB10.8751877482.59E-26
UVMTFCAPRIN2ZNF5100.8809814164.55E-27
UVMTFCAPRIN2ZNF780B0.8817288333.61E-27
UVMTFCAPRIN2ZNF7080.8830311982.41E-27
UVMTFCAPRIN2BAZ2B0.8843365571.59E-27
UVMTFCAPRIN2ZNF4310.8858577089.79E-28
UVMTFCAPRIN2ZNF100.8875153175.72E-28
UVMTFCAPRIN2ZNF440.8895025582.97E-28
UVMTFCAPRIN2ZNF518A0.8898273482.66E-28
UVMTFCAPRIN2CREBZF0.8901913262.36E-28
UVMTFCAPRIN2ZNF4410.8918038021.37E-28
UVMTFCAPRIN2ZNF1950.8983005251.39E-29
UVMTFCAPRIN2ZNF2340.9037148541.82E-30
UVMTFCAPRIN2ZNF2480.9053185399.76E-31
UVMTFCAPRIN2DMTF10.9122278175.81E-32
UVMTFCAPRIN2ZNF250.9123744935.46E-32
UVMTFCAPRIN2ZNF7000.914827251.89E-32
UVMTSGCAPRIN2CHUK0.8035600492.96E-19
UVMTSGCAPRIN2CSNK1A10.8047246922.41E-19
UVMTSGCAPRIN2CDC730.8050360862.27E-19
UVMTSGCAPRIN2ARID20.8071719251.55E-19
UVMTSGCAPRIN2PHF60.8076132361.43E-19
UVMTSGCAPRIN2SP1000.8076717161.41E-19
UVMTSGCAPRIN2RB1CC10.8077869251.38E-19
UVMTSGCAPRIN2RINT10.8099267699.33E-20
UVMTSGCAPRIN2WDR110.8129853435.27E-20
UVMTSGCAPRIN2VEZT0.8159055653.03E-20
UVMTSGCAPRIN2NEDD40.8162133582.86E-20
UVMTSGCAPRIN2INTS60.8171185452.40E-20
UVMTSGCAPRIN2ITGAV0.8204926311.24E-20
UVMTSGCAPRIN2EXTL20.8205989811.22E-20
UVMTSGCAPRIN2ZMYND110.8222616668.75E-21
UVMTSGCAPRIN2ATM0.8230870517.42E-21
UVMTSGCAPRIN2UHRF20.8244694715.62E-21
UVMTSGCAPRIN2TET20.8245360395.55E-21
UVMTSGCAPRIN2CHD10.8245975045.48E-21
UVMTSGCAPRIN2DCLRE1A0.8254255794.63E-21
UVMTSGCAPRIN2FBXW70.8291706042.14E-21
UVMTSGCAPRIN2CCAR10.8295767591.97E-21
UVMTSGCAPRIN2ZNF2920.8317633261.24E-21
UVMTSGCAPRIN2USP330.8353590335.76E-22
UVMTSGCAPRIN2RBBP80.8364398394.55E-22
UVMTSGCAPRIN2CUL50.8389357162.63E-22
UVMTSGCAPRIN2FAM188A0.8403257251.93E-22
UVMTSGCAPRIN2CUL20.8468353934.33E-23
UVMTSGCAPRIN2SUZ120.8477363583.50E-23
UVMTSGCAPRIN2PPM1A0.8574922333.22E-24
UVMTSGCAPRIN2NAPEPLD0.8578087982.97E-24
UVMTSGCAPRIN2TANK0.8669916212.63E-25
UVMTSGCAPRIN2APAF10.877036381.50E-26
UVMTSGCAPRIN2KRIT10.8794047117.37E-27
UVMTSGCAPRIN2PRKAA10.8808597944.72E-27
UVMTSGCAPRIN2MLH30.8828505342.55E-27
UVMTSGCAPRIN2DICER10.8930020739.05E-29
UVMTSGCAPRIN2GORAB0.9115893187.62E-32
UVMTSGCAPRIN2DMTF10.9122278175.81E-32


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Protein structure


check button Protein 3D structure
Visit iCn3D.


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Protein-Protein Interaction


check button Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure

check buttonOverlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure
check button
* Edge colors based on TCGA cancer types.

check button* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))
all structure
Cancer typeTranslation factorInteracting protein coding geneFCadj.pval
KICHCAPRIN2KLHL221.277609782260860.000376403331756592
LUADCAPRIN2TDRD7-5.325498177579150.00100010249745768
STADCAPRIN2DNASE2B-2.025662323733430.00255109980614372
KIRPCAPRIN2LRP6-1.391438672094890.00471024587750435
THCACAPRIN2LRP5-1.645307774331870.00911193391314822
BRCACAPRIN2KLHL221.095518941397670.0107666555369726
LUSCCAPRIN2LRP5-1.219624250157130.0113786513450526
HNSCCAPRIN2DNASE2B1.924752527121290.0192483676533055
LUSCCAPRIN2LRP6-1.401624320505350.0396404633591005
KIRCCAPRIN2LRP5-1.410527902997860.0448370020418361
KIRCCAPRIN2LRP6-1.778319130236771.16831478033445e-08
COADCAPRIN2TDRD7-1.159839385292811.33216381072998e-05
LIHCCAPRIN2KLHL22-4.674888870991224.13231748257069e-06
LUADCAPRIN2DNASE2B-3.738252378581694.92275588120863e-11
BRCACAPRIN2LRP6-1.38193104321916.01400477917354e-14
PRADCAPRIN2TDRD71.200355530384498.50750576591638e-05


check button Protein-protein interactors with this translation factor (BIOGRID-3.4.160)
PPI interactors with CAPRIN2
COPS6, LRP5, LRP6, PEX5, AUP1, FAM8A1, PTEN, MEOX2, NPM1, FXR2, FXR1, BRD2,


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Mutations


check button Clinically associated variants from ClinVar.
GeneChrPositionRefSeqVarSeqRefSeeqVarTypePathogenicDiseaseVarInfo
CAPRIN2chr1230866806AGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant
CAPRIN2chr1230868008CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant
CAPRIN2chr1230872061AGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
CAPRIN2chr1230876188GAsingle_nucleotide_variantBenignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
CAPRIN2chr1230879032AGsingle_nucleotide_variantBenignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
CAPRIN2chr1230884323TGsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
CAPRIN2chr1230884336AGsingle_nucleotide_variantBenignnot_providedSO:0001582|initiatior_codon_variant,SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001582|initiatior_codon_variant,SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
CAPRIN2chr1230886562CATCDeletionUncertain_significancenot_providedSO:0001589|frameshift_variant,SO:0001627|intron_variantSO:0001589|frameshift_variant,SO:0001627|intron_variant


check button nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.
all structure


check button SNVs and Indels
GeneCancer typeChromosomeStartEndRefSeeqMutSeqMutation typeAAchange# samples
CAPRIN2BRCAchr123088806730888067CTMissense_Mutationp.R215Q8
CAPRIN2KIRPchr123088812930888129CTSilentp.A194A7
CAPRIN2BLCAchr123088800130888001TCMissense_Mutation7
CAPRIN2LUADchr123086335730863357CTMissense_Mutationp.E955K5
CAPRIN2LUADchr123088215630882156CTMissense_Mutationp.R403H5
CAPRIN2CESCchr123088180930881809TCMissense_Mutation4
CAPRIN2KIRPchr123090666130906661CGMissense_Mutationp.E13Q4
CAPRIN2PAADchr123090667630906676CTMissense_Mutationp.A8T3
CAPRIN2CESCchr123090635830906358GAMissense_Mutation3
CAPRIN2LIHCchr123086330830863308GAMissense_Mutationp.T971I3
CAPRIN2SKCMchr123087622730876227GAMissense_Mutationp.S670F3
CAPRIN2UCSchr123088175630881756TGMissense_Mutationp.E536D3
CAPRIN2SKCMchr123088193430881934GAMissense_Mutationp.P477L3
CAPRIN2STADchr123086957930869579CTMissense_Mutationp.R776Q3
CAPRIN2BLCAchr123086800230868002CTSilent3
CAPRIN2ESCAchr123088171230881712TAMissense_Mutationp.N551I3
CAPRIN2ESCAchr123090660030906600GAMissense_Mutationp.A33V3
CAPRIN2PAADchr123087379830873798CTMissense_Mutationp.D699N3
CAPRIN2PAADchr123087896930878969AGSilentp.D612D3
CAPRIN2COADchr123088431330884313T-Frame_Shift_Delp.T342fs2
CAPRIN2UCECchr123088444030884440TGMissense_Mutationp.K299N2
CAPRIN2KIRPchr123088657430886574AGMissense_Mutationp.V294A2
CAPRIN2STADchr123086308430863084CTMissense_Mutation2
CAPRIN2UCECchr123086286630862866CTSilentp.T11182
CAPRIN2READchr123090666130906661CTMissense_Mutationp.E13K2
CAPRIN2SKCMchr123086285030862850GAMissense_Mutationp.L1124F2
CAPRIN2HNSCchr123088178030881780TCSilentp.S528S2
CAPRIN2LIHCchr123088223330882233T-Frame_Shift_Delp.E377fs2
CAPRIN2COADchr123088796330887963CANonsense_Mutationp.E250X2
CAPRIN2UCECchr123088444130884441TGMissense_Mutationp.K299T2
CAPRIN2STADchr123089398930893989CTMissense_Mutation2
CAPRIN2UCECchr123086450930864509TGMissense_Mutationp.N936H2
CAPRIN2SKCMchr123086291730862917CGMissense_Mutationp.W1101C2
CAPRIN2STADchr123086319630863196CTSilentp.L1008L2
CAPRIN2LUADchr123088805630888056GCMissense_Mutationp.Q219E2
CAPRIN2LIHCchr123087214630872146G-Frame_Shift_Delp.P721fs2
CAPRIN2UCECchr123088791730887917CAMissense_Mutationp.R265I2
CAPRIN2LAMLchr123079789430797894CTNonsense_Mutationp.W24*2
CAPRIN2PAADchr123086342630863426GASilentp.N890N2
CAPRIN2STADchr123090630830906308TCSilent2
CAPRIN2UCECchr123086957430869574CANonsense_Mutationp.E778*2
CAPRIN2SKCMchr123088184430881844GAMissense_Mutationp.P507L2
CAPRIN2STADchr123086793430867934CGMissense_Mutationp.R870T2
CAPRIN2CESCchr123088163330881633GASilent2
CAPRIN2UCECchr123090629730906297CAMissense_Mutationp.R134I2
CAPRIN2LUADchr123087901030879010CAMissense_Mutationp.V599L2
CAPRIN2UCECchr123086958730869587CTSilentp.L7732
CAPRIN2SKCMchr123086330530863305GAMissense_Mutationp.P972L2
CAPRIN2STADchr123088796830887968GAMissense_Mutationp.S248L2
CAPRIN2CESCchr123088796330887963CGMissense_Mutation2
CAPRIN2HNSCchr123087622230876222GANonsense_Mutationp.Q672*2
CAPRIN2UCECchr123090640330906403GAMissense_Mutationp.R99W2
CAPRIN2STADchr123086308430863084CTMissense_Mutationp.V1046I2
CAPRIN2UCECchr123087736530877365GASilentp.D6422
CAPRIN2SKCMchr123088318130883181GAMissense_Mutationp.P366S2
CAPRIN2CESCchr123086327730863277TASilent2
CAPRIN2HNSCchr123087733330877333GTMissense_Mutationp.P653Q2
CAPRIN2HNSCchr123086953230869532GCMissense_Mutationp.Q792E2
CAPRIN2BLCAchr123087376330873763CAMissense_Mutationp.M710I2
CAPRIN2UCECchr123088158430881584CAMissense_Mutationp.D594Y2
CAPRIN2LUADchr123088802330888023CANonsense_Mutationp.E230*2
CAPRIN2STADchr123090630830906308TCSilentp.K130K2
CAPRIN2SARCchr123088438630884386GASilent2
CAPRIN2ESCAchr123088171230881712TAMissense_Mutation2
CAPRIN2PAADchr123087379830873798CTMissense_Mutation2
CAPRIN2BLCAchr123090654030906540GAMissense_Mutationp.S53L2
CAPRIN2STADchr123089398930893989CTMissense_Mutationp.E179K2
CAPRIN2ESCAchr123087622230876222GTMissense_Mutationp.Q672K2
CAPRIN2CESCchr123088205030882050GASilent2
CAPRIN2UCECchr123088175830881758CANonsense_Mutationp.E536*2
CAPRIN2ESCAchr123087375730873757TASilent2
CAPRIN2PAADchr123087896930878969AGSilent2
CAPRIN2BLCAchr123086338430863384GANonsense_Mutationp.Q946*2
CAPRIN2STADchr123088798830887988AGSilentp.N241N2
CAPRIN2BRCAchr123087213330872133CASilentp.P7252
CAPRIN2UCECchr123088180030881800CTMissense_Mutationp.E522K2
CAPRIN2ESCAchr123090660030906600GAMissense_Mutation2
CAPRIN2PAADchr123090667630906676CTMissense_Mutation2
CAPRIN2BLCAchr123088185830881858CTSilentp.Q502Q2
CAPRIN2UCECchr123088189730881897CAMissense_Mutationp.K489N2
CAPRIN2ESCAchr123087375730873757TASilentp.S712S2
CAPRIN2KIRCchr123086796130867961GCMissense_Mutationp.S861C2
CAPRIN2UCECchr123086285930862859CAMissense_Mutationp.G1121C2
CAPRIN2BLCAchr123086334230863342CAMissense_Mutationp.G960C2
CAPRIN2STADchr123087376530873765TAMissense_Mutationp.M710L2
CAPRIN2BRCAchr123090406930904069TCSplice_Sitee2-22
CAPRIN2ESCAchr123086290730862907GTMissense_Mutationp.H1105N2
CAPRIN2LUADchr123088319630883196GANonsense_Mutationp.Q361*2
CAPRIN2HNSCchr123086300930863009ACMissense_Mutationp.L1071V2
CAPRIN2UCECchr123088214830882148TGMissense_Mutationp.M406L2
CAPRIN2UCECchr123086286030862860TCSilentp.S11202
CAPRIN2SARCchr123088441530884415ACMissense_Mutationp.L308V2
CAPRIN2STADchr123087215930872159CAMissense_Mutationp.A717S2
CAPRIN2CESCchr123088167230881672CTSilent2
CAPRIN2LUADchr123088163630881636GASilentp.S576S2
CAPRIN2SKCMchr123088167130881671TGMissense_Mutationp.I565L2
CAPRIN2LIHCchr123086955230869552G-Frame_Shift_Delp.P785fs2
CAPRIN2BLCAchr123090634330906343CTMissense_Mutationp.E119K1
CAPRIN2GBMchr123088806730888067CTMissense_Mutation1
CAPRIN2LUADchr123086331630863316ATSilentp.R968R1
CAPRIN2SARCchr123088438630884386GASilentp.I317I1
CAPRIN2STADchr123088169630881696T-Frame_Shift_Delp.H557fs1
CAPRIN2HNSCchr123087897530878975CTSilent1
CAPRIN2LIHCchr123088222930882229CAMissense_Mutation1
CAPRIN2LUADchr123086291930862919AGMissense_Mutationp.W1101R1
CAPRIN2LIHCchr123087382830873828A-Frame_Shift_Delp.C689fs1
CAPRIN2MESOchr123088190630881906CAMissense_Mutation1
CAPRIN2UCECchr123086800930868009GTMissense_Mutationp.T845K1
CAPRIN2BLCAchr123088203630882036TAMissense_Mutation1
CAPRIN2CESCchr123088205030882050GASilentp.S4381
CAPRIN2BLCAchr123087212830872128GTNonsense_Mutationp.S727*1
CAPRIN2HNSCchr123086300930863009ACMissense_Mutation1
CAPRIN2LUADchr123086301630863016TAMissense_Mutationp.E1068D1
CAPRIN2PAADchr123086342630863426GASilentp.N945N1
CAPRIN2ACCchr123088319830883198GAMissense_Mutationp.A360V1
CAPRIN2HNSCchr123086789830867898TAMissense_Mutation1
CAPRIN2LIHCchr123086331730863317CTMissense_Mutationp.R968H1
CAPRIN2READchr123088205630882056TGSilentp.A436A1
CAPRIN2LIHCchr123087894830878948T-Frame_Shift_Delp.K619fs1
CAPRIN2MESOchr123087898030878980GCMissense_Mutation1
CAPRIN2SKCMchr123086791930867919GAMissense_Mutationp.S875F1
CAPRIN2UCECchr123086673230866732GTMissense_Mutationp.P913H1
CAPRIN2BLCAchr123087892930878929GCMissense_Mutation1
CAPRIN2COADchr123086293830862938GCSilentp.L1094L1
CAPRIN2HNSCchr123086789830867898TAMissense_Mutationp.Y882F1
CAPRIN2BLCAchr123088191930881919CTMissense_Mutationp.G482E1
CAPRIN2COADchr123088808430888084AGSilentp.A209A1
CAPRIN2HNSCchr123088170530881705CGMissense_Mutation1
CAPRIN2BLCAchr123087376330873763CAMissense_Mutation1
CAPRIN2HNSCchr123086789930867899ATMissense_Mutation1
CAPRIN2LIHCchr123086322130863221ACMissense_Mutationp.F1000C1
CAPRIN2LUADchr123086344530863445TGMissense_Mutationp.N884T1
CAPRIN2READchr123088807230888072CAMissense_Mutationp.K213N1
CAPRIN2HNSCchr123086789930867899ATMissense_Mutationp.Y882N1
CAPRIN2LIHCchr123088437230884372T-Translation_Start_Site1
CAPRIN2MESOchr123087898030878980GCMissense_Mutationp.L609V1
CAPRIN2SKCMchr123088795730887957CTMissense_Mutationp.D252N1
CAPRIN2UCECchr123087203130872031GTSilentp.P759P1
CAPRIN2BLCAchr123087902030879020CASilent1
CAPRIN2COADchr123086336530863365C-Frame_Shift_Delp.R952fs1
CAPRIN2BLCAchr123088203630882036TAMissense_Mutationp.K443I1
CAPRIN2COADchr123089402930894029CAMissense_Mutationp.E165D1
CAPRIN2HNSCchr123088178030881780TCSilent1
CAPRIN2LGGchr123090634730906347CTSilentp.A117A1
CAPRIN2PAADchr123087375030873750GCMissense_Mutationp.P715A1
CAPRIN2STADchr123090651430906515AA-Frame_Shift_Delp.62_62del1
CAPRIN2BLCAchr123090654030906540GAMissense_Mutation1
CAPRIN2HNSCchr123087892930878929GANonsense_Mutationp.Q626*1
CAPRIN2LUADchr123087214830872148GASilentp.P720P1
CAPRIN2SARCchr123086677030866770GTMissense_Mutation1
CAPRIN2LIHCchr123089397730893977T-Frame_Shift_Delp.T183fs1
CAPRIN2OVchr123090645830906458CTSilentp.G80G1
CAPRIN2SKCMchr123086799830867998GAMissense_Mutationp.P849S1
CAPRIN2UCECchr123086290830862908CTSilentp.L1104L1
CAPRIN2BLCAchr123090664130906641CGMissense_Mutation1
CAPRIN2COADchr123086450530864505GAMissense_Mutationp.S881L1
CAPRIN2BLCAchr123087892930878929GCMissense_Mutationp.Q626E1
CAPRIN2DLBCchr123088188430881884GAMissense_Mutationp.P494S1
CAPRIN2HNSCchr123086953230869532GCMissense_Mutation1
CAPRIN2LGGchr123088209630882096CAMissense_Mutationp.W423L1
CAPRIN2PRADchr123088797830887978AGMissense_Mutationp.Y245H1
CAPRIN2STADchr123090651430906515AA-Frame_Shift_Delp.FS61fs1
CAPRIN2BLCAchr123088185830881858CTSilent1
CAPRIN2LIHCchr123086307230863073-AFrame_Shift_Insp.LH1049fs1
CAPRIN2LUADchr123088202730882027GTMissense_Mutationp.T446N1
CAPRIN2SARCchr123088441530884415ACMissense_Mutation1
CAPRIN2ESCAchr123087622230876222GTMissense_Mutation1
CAPRIN2LIHCchr123090403430904034T-Frame_Shift_Delp.S152fs1
CAPRIN2PAADchr123086342630863426GASilent1
CAPRIN2SKCMchr123088443030884430CTMissense_Mutationp.D303N1
CAPRIN2UCECchr123086294930862949TAMissense_Mutationp.I1091F1
CAPRIN2COADchr123086453230864532CTMissense_Mutationp.G872E1
CAPRIN2BLCAchr123090664130906641CGMissense_Mutationp.K19N1
CAPRIN2ESCAchr123087375730873757TASilentp.S7121
CAPRIN2UCSchr123088175630881756TGMissense_Mutation1
CAPRIN2HNSCchr123086680630866806AGSilent1
CAPRIN2LGGchr123086315030863150TGMissense_Mutationp.N1024H1
CAPRIN2PRADchr123090404230904042CGMissense_Mutationp.R149P1
CAPRIN2STADchr123088224630882246CTMissense_Mutationp.R373H1
CAPRIN2CESCchr123087203530872035GTMissense_Mutation1
CAPRIN2HNSCchr123088183030881830GAMissense_Mutationp.P512S1
CAPRIN2LIHCchr123088813130888132-TFrame_Shift_Insp.NA193fs1
CAPRIN2LUADchr123088165430881655CCAAMissense_Mutationp.W570F1
CAPRIN2HNSCchr123087209130872091ACSilentp.S739S1
CAPRIN2LIHCchr123086289230862892A-Frame_Shift_Delp.Y1110fs1
CAPRIN2SKCMchr123086805230868052TCMissense_Mutationp.I831V1
CAPRIN2UCECchr123088794130887941ATMissense_Mutationp.F257Y1
CAPRIN2COADchr123086955930869559CANonsense_Mutationp.E748X1
CAPRIN2BLCAchr123087902030879020CASilentp.V595V1
CAPRIN2HNSCchr123088183030881830GAMissense_Mutation1
CAPRIN2LGGchr123086315030863150TGMissense_Mutation1
CAPRIN2LUADchr123088165530881655CAMissense_Mutationp.W570L1
CAPRIN2PRADchr123086797330867973TAMissense_Mutationp.N857I1
CAPRIN2LUSCchr123088440330884403CAMissense_Mutationp.G312C1
CAPRIN2SARCchr123086327830863278GTMissense_Mutation1
CAPRIN2HNSCchr123087897530878975CTSilentp.P610P1
CAPRIN2LIHCchr123090628130906282-TFrame_Shift_Insp.K139fs1
CAPRIN2HNSCchr123087375430873754CGMissense_Mutationp.E713D1
CAPRIN2LIHCchr123086675930866759A-Frame_Shift_Delp.F904fs1
CAPRIN2SKCMchr123088181130881811GAMissense_Mutationp.S518F1
CAPRIN2UCECchr123086960830869608TASilentp.V766V1
CAPRIN2COADchr123087619130876191ATSplice_Site.1
CAPRIN2HNSCchr123087375430873754CGMissense_Mutation1
CAPRIN2LGGchr123088209630882096CAMissense_Mutation1
CAPRIN2LUADchr123088165430881654CAMissense_Mutationp.W570C1
CAPRIN2READchr123086306130863061CTSilentp.K1053K1
CAPRIN2LUSCchr123086801330868013GANonsense_Mutationp.Q844*1
CAPRIN2SKCMchr123086791930867919GAMissense_Mutationp.S819F1
CAPRIN2THCAchr123086308530863085GASilent1
CAPRIN2BLCAchr123086334230863342CAMissense_Mutation1
CAPRIN2CESCchr123088796330887963CGMissense_Mutationp.E250Q1
CAPRIN2HNSCchr123088436930884369GAMissense_Mutationp.A323V1
CAPRIN2LIHCchr123090630030906301-TFrame_Shift_Insp.*133fs1
CAPRIN2KIRCchr123086806130868061CTMissense_Mutationp.D828N1
CAPRIN2LIHCchr123088171530881715T-Frame_Shift_Delp.N551fs1
CAPRIN2SKCMchr123086679630866796GAMissense_Mutationp.P892S1
CAPRIN2UCECchr123090641230906412C-Frame_Shift_Delp.E96fs1
CAPRIN2COADchr123087736730877367CGMissense_Mutationp.D642H1
CAPRIN2SARCchr123087206530872065GTMissense_Mutation1
CAPRIN2STADchr123088165630881656AGMissense_Mutationp.W570R1
CAPRIN2HNSCchr123087209130872091ACSilent1
CAPRIN2LIHCchr123086338530863385AGMissense_Mutation1
CAPRIN2LUADchr123087208830872088TCSilentp.E740E1
CAPRIN2READchr123086306230863062TGMissense_Mutationp.K1053T1
CAPRIN2LUSCchr123086796730867967CTMissense_Mutationp.R859Q1
CAPRIN2SKCMchr123086799830867998GAMissense_Mutationp.P793S1
CAPRIN2THYMchr123087208330872083CTMissense_Mutationp.G742D1
CAPRIN2BLCAchr123086331830863318GTMissense_Mutation1
CAPRIN2CESCchr123086327730863277TASilentp.A9811
CAPRIN2HNSCchr123088170530881705CGMissense_Mutationp.E553D1
CAPRIN2LIHCchr123090638730906388-GFrame_Shift_Insp.A104fs1
CAPRIN2LIHCchr123088439530884395A-Frame_Shift_Delp.F314fs1
CAPRIN2SKCMchr123086793330867933TCSilentp.R870R1
CAPRIN2COADchr123087738030877380AGSilentp.S637S1
CAPRIN2SARCchr123087208230872082GTSilent1
CAPRIN2HNSCchr123088443130884431CGMissense_Mutation1
CAPRIN2LIHCchr123086330830863308GAMissense_Mutation1
CAPRIN2READchr123088214930882149AGSilentp.D405D1
CAPRIN2LIHCchr123088222630882226A-Frame_Shift_Delp.Y380fs1
CAPRIN2LUSCchr123087382030873820TCSilentp.S691S1
CAPRIN2SKCMchr123086793330867933TCSilentp.R814R1
CAPRIN2THYMchr123088196830881968TCMissense_Mutationp.K466E1
CAPRIN2BLCAchr123090634330906343CTMissense_Mutation1
CAPRIN2CESCchr123088163330881633GASilentp.L5771
CAPRIN2LIHCchr123088212130882122-TTGTTCIn_Frame_Insp.414_415EE>ENKE1
CAPRIN2GBMchr123088811630888116GAMissense_Mutation1
CAPRIN2LIHCchr123088807330888073T-Frame_Shift_Delp.K213fs1
CAPRIN2STADchr123090651430906515AA-Frame_Shift_Del1
CAPRIN2BLCAchr123090667930906679GANonsense_Mutationp.Q7*1
CAPRIN2COADchr123088180130881801GASilentp.S521S1
CAPRIN2HNSCchr123088436930884369GAMissense_Mutation1
CAPRIN2LIHCchr123090635230906352GTMissense_Mutation1
CAPRIN2READchr123090630230906302TGMissense_Mutationp.K132N1
CAPRIN2LIHCchr123088799530887995C-Frame_Shift_Delp.G239fs1
CAPRIN2MESOchr123086468730864687CAMissense_Mutation1
CAPRIN2UCECchr123086958730869587CTSilentp.L773L1
CAPRIN2BLCAchr123088191930881919CTMissense_Mutation1
CAPRIN2CESCchr123088167230881672CTSilentp.Q5641
CAPRIN2HNSCchr123088443130884431CGMissense_Mutationp.K302N1

check buttonCopy number variation (CNV) of CAPRIN2
* Click on the image to open the original image in a new window.
all structure

check buttonFusion gene breakpoints (product of the structural variants (SVs)) across CAPRIN2
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


check button Fusion genes with this translation factor from FusionGDB2.0.
FusionGDB2 IDDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
71068SARCTCGA-DX-AB2H-01AADSSchr1244579283-CAPRIN2chr1230864563-
71068N/AAX795402AZGP1chr799573584-CAPRIN2chr1230863313-
71068N/AAX795404AZGP1chr799573584-CAPRIN2chr1230863309-
71068N/AAX795406AZGP1chr799573583-CAPRIN2chr1230863267-
71068N/AAX795408AZGP1chr799573583-CAPRIN2chr1230863246-
71068N/AAX795410AZGP1chr799573584-CAPRIN2chr1230863228-
12949BRCATCGA-D8-A13Y-01ACAPRIN2chr1230869442-AMN1chr1231867885-
12949BRCATCGA-D8-A13Y-01ACAPRIN2chr1230869442-AMN1chr1231872290-
101572STADTCGA-BR-6709CAPRIN2chr1230883172-EML2chr1946113046-
82204SKCMTCGA-D3-A3CC-06ACAPRIN2chr1230893954-R3HDM2chr1257697000-
82204SKCMTCGA-D3-A3CC-06ACAPRIN2chr1230893954-R3HDM2chr1257699446-
87049BRCATCGA-A7-A0CJ-01ACAPRIN2chr1230904005-ST8SIA1chr1222223559-
71068STADTCGA-CD-5803-01APWWP2Bchr10134219490+CAPRIN2chr1230906493-
71103LUADTCGA-86-7954-01AR3HDM2chr1257789532-CAPRIN2chr1230894040-
71103LUADTCGA-86-7954-01AR3HDM2chr1257789532-CAPRIN2chr1230904067-


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Prognostic Analysis


check button Kaplan-Meier plots with logrank tests of overall survival (OS)
all structure
Cancer typeTranslation factorCoefficentHazard ratioWald test pvalLikelihool ratio pvalLogrank test pval# samples


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Translation factor and Gender


check button Differential gene expression between female and male. (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
KICHCAPRIN20.003937664541667930.11
ESCACAPRIN20.009843272156443680.27

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Translation factor and Age


check button Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
TGCTCAPRIN20.02862983807614010.86
LGGCAPRIN20.00387275259816590.13
OVCAPRIN20.007552015522531010.24
ESCACAPRIN20.01987062504379470.62

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Related Drugs


check button Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases


check button Diseases associated with this translation factor.
(DisGeNet 4.0)
Disease IDDisease Name# PubMedsDisease source