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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: PADI6 (NCBI Gene ID:353238)

Gene Summary

Gene Summary

Gene Information	Gene Name: PADI6
	Gene ID: 353238
	Gene Symbol	PADI6
	Gene ID	353238
	Gene Name	peptidyl arginine deiminase 6
	Synonyms	PREMBL2\|hPADVI
	Cytomap	1p36.13
	Type of Gene	protein-coding
	Description	protein-arginine deiminase type-6peptidyl arginine deiminase, type VIpeptidyl arginine deiminase-like proteinpeptidylarginine deiminase type 6
	Modification date	20200313
	UniProtAcc	Q6TGC4

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0043143	Regulation of translation by machinery localization
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
PADI6	(67.6 - 355.7]

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Translation Studies in PubMed

We searched PubMed using 'PADI6[title] AND translation [title] AND human.'

Gene	Title	PMID
PADI6	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

ORF

Exon skipping position in the amino acid sequence.

ENST

Exon skip start (DNA)

Exon Skip end (DNA)

Len(transcript seq)

Exon skip start (mRNA)

Exon Skip end (mRNA)

Len(amino acid seq)

Exon skip start (AA)

Exon Skip end (AA)

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
BRCA	PADI6	-3.78499078181357	0.000129376845570936

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
UCEC	PADI6	3	2	0.0228558538505626	0.711342181069959	0.509326151761518	0.222952399098209	0.0962773313476607

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
KIRC	PADI6	3	2	0.0454854452582152	0.794790921866217	0.520323076923077	-0.351577063924531	-0.666916212971092
SKCM	PADI6	3	2	0.0466608356020522	0.730661826347305	0.488678035714286	0.0672202909445605	-0.10338857560843

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
LGG	PADI6	0.231507322	0.001055881
LIHC	PADI6	0.052675835	0.043040225

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with PADI6 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	CGC	PADI6	TLX3	0.8243526	3.43E-12
CHOL	TF	PADI6	TLX3	0.8243526	3.43E-12

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
THCA	PADI6	ZAR1	-6.3115942625464	0.000643096429992795
BRCA	PADI6	ZAR1L	-1.43552662887974	0.00130864564001974
LUSC	PADI6	ZAR1L	-2.58031809554772	0.00182371710054537
COAD	PADI6	NPM2	-1.35899338598868	0.00197160243988037
ESCA	PADI6	NPM2	-6.41448801325906	0.0048828125
LIHC	PADI6	ZAR1L	-2.82831742915807	0.00584076338898049
LUSC	PADI6	ZAR1	-4.76596582823308	0.00753148348807362
KICH	PADI6	ZAR1L	1.40471366673396	0.0208625823327655
BLCA	PADI6	OOEP	1.06930103603674	0.0309840500984566
LUSC	PADI6	OOEP	-2.29895205987071	0.0345094573036436
KIRC	PADI6	FIGLA	-1.73979205740682	0.0382688764522297
HNSC	PADI6	ZAR1L	-1.35969590956752	0.0454587523438197
BRCA	PADI6	NPM2	2.33682708030626	1.21368585808608e-16
HNSC	PADI6	TLE6	1.51828459354716	5.90311856285554e-07
PRAD	PADI6	TLE6	2.75219283683045	7.28604434373912e-06
BRCA	PADI6	FIGLA	-3.72091969978518	8.33731190539693e-14

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with PADI6

SUV39H1, KLHL2, ZNF526, USP4, UHRF1, CAMKK1, KLHL28, EBF2, BRMS1, PER1, MN1, APPBP2, DHPS,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
PADI6	chr1	17699720	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PADI6	chr1	17707625	G	C	single_nucleotide_variant	Uncertain_significance	Premature_ovarian_failure	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PADI6	chr1	17708541	T	A	single_nucleotide_variant	Pathogenic	Preimplantation_embryonic_lethality_2	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PADI6	chr1	17718616	C	T	single_nucleotide_variant	Pathogenic	Preimplantation_embryonic_lethality_2	SO:0001587\|nonsense	SO:0001587\|nonsense
PADI6	chr1	17720537	C	T	single_nucleotide_variant	Pathogenic	Preimplantation_embryonic_lethality_2	SO:0001587\|nonsense	SO:0001587\|nonsense
PADI6	chr1	17722159	G	A	single_nucleotide_variant	Pathogenic	Preimplantation_embryonic_lethality_2	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PADI6	chr1	17722363	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PADI6	chr1	17723587	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PADI6	chr1	17727855	CAG	C	Microsatellite	Pathogenic	Preimplantation_embryonic_lethality_2	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
PADI6	BLCA	chr1	17721722	17721723	GA	-	RNA		43
PADI6	BLCA	chr1	17723476	17723477	-	CA	RNA		16
PADI6	BLCA	chr1	17720687	17720687	G	-	RNA		11
PADI6	ESCA	chr1	17699379	17699380	-	AC	RNA		6
PADI6	LIHC	chr1	17718392	17718393	-	CTT	RNA		5
PADI6	KIRC	chr1	17725285	17725286	AC	-	RNA		4
PADI6	BRCA	chr1	17714946	17714946	G	A	Silent	p.G250	3
PADI6	CESC	chr1	17698725	17698725	C	T	RNA		3
PADI6	BLCA	chr1	17699682	17699682	C	A	RNA		3
PADI6	ESCA	chr1	17706689	17706690	-	T	RNA		3
PADI6	SKCM	chr1	17721594	17721594	G	A	RNA		2
PADI6	LUAD	chr1	17708469	17708469	G	A	Silent	p.T187T	2
PADI6	SARC	chr1	17707595	17707595	C	A	RNA		2
PADI6	BRCA	chr1	17701986	17701986	C	G	Missense_Mutation	p.T120S	2
PADI6	HNSC	chr1	17727771	17727771	G	A	RNA		2
PADI6	BLCA	chr1	17698755	17698755	G	C	RNA		2
PADI6	CESC	chr1	17707601	17707601	T	C	RNA		2
PADI6	THCA	chr1	17720532	17720532	C	T	RNA		2
PADI6	BLCA	chr1	17727817	17727817	C	A	RNA		2
PADI6	BLCA	chr1	17727832	17727832	C	G	RNA		2
PADI6	STAD	chr1	17720850	17720850	A	G	Missense_Mutation	p.M413V	2
PADI6	CHOL	chr1	17725155	17725162	CCCCCCCA	-	RNA		2
PADI6	PAAD	chr1	17722154	17722154	C	T	RNA		2
PADI6	BLCA	chr1	17708559	17708559	G	C	RNA		2
PADI6	STAD	chr1	17721556	17721556	G	C	Missense_Mutation	p.E483Q	2
PADI6	KIRC	chr1	17727910	17727910	C	T	RNA		2
PADI6	THYM	chr1	17718676	17718676	G	T	Silent	p.V343V	2
PADI6	ESCA	chr1	17707573	17707573	G	A	RNA		2
PADI6	STAD	chr1	17721561	17721561	C	A	Missense_Mutation	p.F484L	2
PADI6	ESCA	chr1	17707635	17707635	A	C	RNA		2
PADI6	LIHC	chr1	17701956	17701956	C	-	RNA		2
PADI6	LIHC	chr1	17720878	17720878	C	-	RNA		2
PADI6	LIHC	chr1	17714988	17714988	C	-	RNA		2
PADI6	BLCA	chr1	17699682	17699682	C	A	Missense_Mutation	p.A83D	1
PADI6	GBM	chr1	17721458	17721458	G	A	Missense_Mutation	p.R450Q	1
PADI6	SKCM	chr1	17698840	17698840	T	G	RNA		1
PADI6	STAD	chr1	17727905	17727905	G	A	Missense_Mutation	p.A686T	1
PADI6	DLBC	chr1	17701957	17701957	C	T	Silent	p.A110A	1
PADI6	LGG	chr1	17721696	17721698	TTT	-	RNA		1
PADI6	LIHC	chr1	17720767	17720767	C	-	RNA		1
PADI6	SKCM	chr1	17699608	17699608	C	T	RNA		1
PADI6	UCS	chr1	17727969	17727969	G	A	RNA		1
PADI6	ESCA	chr1	17720816	17720816	G	T	RNA		1
PADI6	LUAD	chr1	17723578	17723578	A	G	RNA		1
PADI6	SKCM	chr1	17721594	17721594	G	A	Silent	p.E495E	1
PADI6	SKCM	chr1	17723605	17723605	G	A	RNA		1
PADI6	GBM	chr1	17708559	17708559	G	A	Silent	p.S217S	1
PADI6	LUAD	chr1	17721512	17721512	C	A	Missense_Mutation	p.P468Q	1
PADI6	SKCM	chr1	17698834	17698834	G	A	RNA		1
PADI6	STAD	chr1	17707627	17707627	A	G	Missense_Mutation	p.D174G	1
PADI6	ESCA	chr1	17698739	17698739	G	T	RNA	NULL	1
PADI6	LIHC	chr1	17715043	17715043	T	C	RNA		1
PADI6	LIHC	chr1	17720789	17720789	C	-	RNA		1
PADI6	SARC	chr1	17715314	17715314	C	A	RNA		1
PADI6	SKCM	chr1	17722083	17722083	C	T	RNA		1
PADI6	ESCA	chr1	17715326	17715326	T	C	RNA		1
PADI6	LUAD	chr1	17708498	17708498	A	T	RNA		1
PADI6	SKCM	chr1	17698834	17698834	G	A	Missense_Mutation	p.E32K	1
PADI6	SKCM	chr1	17701943	17701943	C	T	RNA		1
PADI6	LUAD	chr1	17707550	17707550	G	C	Missense_Mutation	p.W148C	1
PADI6	SKCM	chr1	17723567	17723567	G	A	RNA		1
PADI6	STAD	chr1	17721598	17721598	A	-	Frame_Shift_Del	p.K497fs	1
PADI6	ESCA	chr1	17707573	17707573	G	A	RNA	NULL	1
PADI6	LIHC	chr1	17727827	17727827	T	C	RNA		1
PADI6	LIHC	chr1	17720802	17720802	G	-	RNA		1
PADI6	SARC	chr1	17720809	17720809	G	T	RNA		1
PADI6	SKCM	chr1	17722084	17722084	C	T	RNA		1
PADI6	ESCA	chr1	17715326	17715326	T	C	Missense_Mutation	p.C305R	1
PADI6	LUAD	chr1	17725322	17725322	G	A	RNA		1
PADI6	SKCM	chr1	17720578	17720578	G	A	Silent	p.L394L	1
PADI6	SKCM	chr1	17708551	17708551	G	A	RNA		1
PADI6	HNSC	chr1	17727771	17727771	G	A	Missense_Mutation	p.C641Y	1
PADI6	LUSC	chr1	17699703	17699703	C	A	Missense_Mutation	p.P90H	1
PADI6	SKCM	chr1	17721601	17721601	A	C	RNA		1
PADI6	TGCT	chr1	17706676	17706676	G	-	RNA		1
PADI6	ESCA	chr1	17707635	17707635	A	C	RNA	NULL	1
PADI6	LIHC	chr1	17727872	17727872	T	C	RNA		1
PADI6	LIHC	chr1	17727745	17727745	T	-	RNA		1
PADI6	SARC	chr1	17721684	17721684	G	-	RNA		1
PADI6	SKCM	chr1	17714972	17714972	T	C	RNA		1
PADI6	ESCA	chr1	17707635	17707635	A	C	Missense_Mutation	p.T177P	1
PADI6	LUAD	chr1	17708503	17708503	C	A	RNA		1
PADI6	SKCM	chr1	17727763	17727763	G	A	Silent	p.K638K	1
PADI6	SKCM	chr1	17706448	17706448	G	A	RNA		1
PADI6	KIRC	chr1	17725285	17725286	AC	-	Frame_Shift_Del	p.598_598del	1
PADI6	LUSC	chr1	17708501	17708501	G	T	Missense_Mutation	p.G198V	1
PADI6	SKCM	chr1	17727763	17727763	G	A	RNA		1
PADI6	SARC	chr1	17707595	17707595	C	A	RNA	NULL	1
PADI6	ESCA	chr1	17715326	17715326	T	C	RNA	NULL	1
PADI6	LIHC	chr1	17715300	17715300	A	G	RNA		1
PADI6	LIHC	chr1	17718608	17718608	G	-	RNA		1
PADI6	SKCM	chr1	17727845	17727845	T	G	RNA		1
PADI6	ESCA	chr1	17707573	17707573	G	A	Missense_Mutation	p.G156D	1
PADI6	LUAD	chr1	17708469	17708469	G	A	RNA		1
PADI6	SKCM	chr1	17714943	17714943	C	T	Silent	p.L249L	1
PADI6	SKCM	chr1	17706441	17706441	C	G	RNA		1
PADI6	CHOL	chr1	17725151	17725154	CCCC	-	RNA		1
PADI6	KIRC	chr1	17721532	17721532	T	A	Missense_Mutation	p.W475R	1
PADI6	PAAD	chr1	17722154	17722154	C	T	Missense_Mutation	p.S538F	1
PADI6	SKCM	chr1	17721516	17721516	G	A	RNA		1
PADI6	LIHC	chr1	17721546	17721546	C	-	RNA		1
PADI6	SKCM	chr1	17721601	17721601	A	C	Missense_Mutation	p.K498Q	1
PADI6	THCA	chr1	17720532	17720532	C	T	Missense_Mutation	p.T379I	1
PADI6	ESCA	chr1	17720816	17720816	G	T	RNA	NULL	1
PADI6	SKCM	chr1	17698794	17698794	C	T	RNA		1
PADI6	ESCA	chr1	17720816	17720816	G	T	Missense_Mutation	p.M401I	1
PADI6	LUAD	chr1	17721512	17721512	C	A	RNA		1
PADI6	SKCM	chr1	17727845	17727845	T	G	Missense_Mutation	p.C666G	1
PADI6	KIRC	chr1	17727910	17727910	C	T	Silent	p.F687F	1
PADI6	SKCM	chr1	17725327	17725327	C	T	RNA		1
PADI6	LIHC	chr1	17725348	17725348	G	-	RNA		1
PADI6	SKCM	chr1	17706448	17706448	G	A	Missense_Mutation	p.G134E	1
PADI6	THYM	chr1	17718676	17718676	G	T	RNA		1
PADI6	ESCA	chr1	17720864	17720864	G	T	RNA	NULL	1
PADI6	LIHC	chr1	17719477	17719478	-	A	RNA		1
PADI6	SKCM	chr1	17720863	17720863	G	A	RNA		1
PADI6	LUAD	chr1	17707550	17707550	G	C	RNA		1
PADI6	SKCM	chr1	17725327	17725327	C	T	Missense_Mutation	p.P612L	1
PADI6	COAD	chr1	17707541	17707542	-	A	Splice_Site	.	1
PADI6	PAAD	chr1	17721702	17721703	-	C	RNA		1
PADI6	SKCM	chr1	17714998	17714998	G	A	RNA		1
PADI6	LIHC	chr1	17719645	17719645	A	-	RNA		1
PADI6	LIHC	chr1	17721694	17721695	TG	-	RNA		1
PADI6	SKCM	chr1	17699608	17699608	C	T	Silent	p.I58I	1
PADI6	SKCM	chr1	17723616	17723616	G	A	RNA		1
PADI6	ESCA	chr1	17701722	17701723	-	A	RNA		1
PADI6	LUAD	chr1	17721696	17721696	T	-	RNA		1
PADI6	SKCM	chr1	17715363	17715363	T	G	Missense_Mutation	p.V317G	1
PADI6	COAD	chr1	17720848	17720848	G	A	Missense_Mutation	p.S412N	1
PADI6	PCPG	chr1	17718672	17718672	G	-	Frame_Shift_Del	p.Q342fs	1
PADI6	ESCA	chr1	17698739	17698739	G	T	RNA		1
PADI6	LIHC	chr1	17718728	17718728	C	-	RNA		1
PADI6	LUAD	chr1	17708504	17708504	C	A	RNA		1
PADI6	SKCM	chr1	17720863	17720863	G	A	Missense_Mutation	p.G417E	1
PADI6	THYM	chr1	17725151	17725151	C	-	RNA		1
PADI6	SKCM	chr1	17720899	17720899	G	A	RNA		1
PADI6	LUAD	chr1	17714922	17714922	C	G	Missense_Mutation	p.H242Q	1
PADI6	SKCM	chr1	17706476	17706476	G	A	Silent	p.Q143Q	1
PADI6	STAD	chr1	17721598	17721598	A	-	Frame_Shift_Del	p.G496fs	1
PADI6	COAD	chr1	17727796	17727796	C	T	Silent	p.C649C	1
PADI6	KIRP	chr1	17721468	17721468	T	C	Silent	p.S453S	1
PADI6	PRAD	chr1	17727705	17727705	G	A	RNA		1
PADI6	SKCM	chr1	17715363	17715363	T	G	RNA		1
PADI6	UCEC	chr1	17721534	17721534	G	A	Nonsense_Mutation	p.W475*	1
PADI6	LUAD	chr1	17714922	17714922	C	G	RNA		1
PADI6	SKCM	chr1	17701943	17701943	C	T	Missense_Mutation	p.P106S	1
PADI6	SKCM	chr1	17706476	17706476	G	A	RNA		1
PADI6	GBM	chr1	17699701	17699701	G	A	Silent	p.S89S	1
PADI6	LUAD	chr1	17708498	17708498	A	T	Missense_Mutation	p.Q197L	1
PADI6	SKCM	chr1	17714972	17714972	T	C	Missense_Mutation	p.V259A	1
PADI6	STAD	chr1	17721478	17721478	C	T	RNA		1
PADI6	DLBC	chr1	17727847	17727847	T	C	Silent	p.C666C	1
PADI6	LGG	chr1	17698767	17698767	G	A	RNA		1
PADI6	PRAD	chr1	17701957	17701957	C	T	RNA		1
PADI6	SKCM	chr1	17723631	17723631	C	T	RNA		1
PADI6	UCEC	chr1	17725290	17725290	C	T	Missense_Mutation	p.P600S	1
PADI6	ESCA	chr1	17720864	17720864	G	T	RNA		1
PADI6	LUAD	chr1	17723626	17723626	G	C	RNA		1
PADI6	SKCM	chr1	17708551	17708551	G	A	Missense_Mutation	p.E215K	1

Copy number variation (CNV) of PADI6
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across PADI6
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Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
6188	ESCA	TCGA-L5-A88V	ARHGEF10L	chr1	17930086	+	PADI6	chr1	17714875	+
6188	ESCA	TCGA-L5-A88V	ARHGEF10L	chr1	17930086	+	PADI6	chr1	17714876	+
6188	ESCA	TCGA-L5-A88V	ARHGEF10L	chr1	17930086	+	PADI6	chr1	17714879	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
GBM	PADI6	0.00496986963788	0.14
TGCT	PADI6	0.0138938556497662	0.38

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
THYM	PADI6	0.0419947363445288	1

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Q6TGC4	DB00155	Citrulline	Product of	Small molecule	Investigational\|Nutraceutical
Q6TGC4	DB00155	Citrulline	Product of

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C4310659	PREIMPLANTATION EMBRYONIC LETHALITY 2	1	CTD_human;UNIPROT