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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:SLC35A1-LRRFIP1 (FusionGDB2 ID:HG10559TG9208)

Fusion Gene Summary for SLC35A1-LRRFIP1

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC35A1-LRRFIP1
Fusion gene ID: hg10559tg9208
HgeneTgene
Gene symbol

SLC35A1

LRRFIP1

Gene ID

10559

9208

Gene namesolute carrier family 35 member A1LRR binding FLII interacting protein 1
SynonymsCDG2F|CMPST|CST|hCSTFLAP-1|FLAP1|FLIIAP1|GCF-2|GCF2|HUFI-1|TRIP
Cytomap('SLC35A1')('LRRFIP1')

6q15

2q37.3

Type of geneprotein-codingprotein-coding
DescriptionCMP-sialic acid transporterCMP-SA-TrCMP-Sia-Trmutated CMP-sialic acid transporter A1solute carrier family 35 (CMP-sialic acid transporter), member 1solute carrier family 35 (CMP-sialic acid transporter), member A1solute carrier family 35 (UDP-galactleucine-rich repeat flightless-interacting protein 1GC-binding factor 2LRR FLII-interacting protein 1NEDD8-conjugating enzymeTAR RNA-interacting proteinleucine rich repeat (in FLII) interacting protein 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000464978, ENST00000369552, 
ENST00000369556, ENST00000369557, 
ENST00000544441, 
Fusion gene scores* DoF score4 X 3 X 3=3614 X 13 X 6=1092
# samples 315
** MAII scorelog2(3/36*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1092*10)=-2.86393845042397
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC35A1 [Title/Abstract] AND LRRFIP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSLC35A1(88211028)-LRRFIP1(238617187), # samples:1
Anticipated loss of major functional domain due to fusion event.SLC35A1-LRRFIP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC35A1-LRRFIP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC35A1-LRRFIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SLC35A1-LRRFIP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLRRFIP1

GO:0000122

negative regulation of transcription by RNA polymerase II

14522076


check buttonFusion gene breakpoints across SLC35A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across LRRFIP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A8BU-01ASLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+


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Fusion Gene ORF analysis for SLC35A1-LRRFIP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000464978ENST00000308482SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
3UTR-intronENST00000464978ENST00000244815SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
3UTR-intronENST00000464978ENST00000289175SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
3UTR-intronENST00000464978ENST00000392000SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
3UTR-intronENST00000464978ENST00000468950SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369552ENST00000244815SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369552ENST00000289175SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369552ENST00000392000SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369552ENST00000468950SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369556ENST00000244815SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369556ENST00000289175SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369556ENST00000392000SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369556ENST00000468950SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369557ENST00000244815SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369557ENST00000289175SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369557ENST00000392000SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000369557ENST00000468950SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000544441ENST00000244815SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000544441ENST00000289175SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000544441ENST00000392000SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
5CDS-intronENST00000544441ENST00000468950SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
In-frameENST00000369552ENST00000308482SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
In-frameENST00000369556ENST00000308482SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
In-frameENST00000369557ENST00000308482SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+
In-frameENST00000544441ENST00000308482SLC35A1chr6

88211028

-LRRFIP1chr2

238617187

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369556SLC35A1chr688211028-ENST00000308482LRRFIP1chr2238617187+3196586222412796
ENST00000544441SLC35A1chr688211028-ENST00000308482LRRFIP1chr2238617187+29873772362203655
ENST00000369552SLC35A1chr688211028-ENST00000308482LRRFIP1chr2238617187+3144534272360777
ENST00000369557SLC35A1chr688211028-ENST00000308482LRRFIP1chr2238617187+311750702333777

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369556ENST00000308482SLC35A1chr688211028-LRRFIP1chr2238617187+0.0015284450.99847156
ENST00000544441ENST00000308482SLC35A1chr688211028-LRRFIP1chr2238617187+0.0008207550.9991792
ENST00000369552ENST00000308482SLC35A1chr688211028-LRRFIP1chr2238617187+0.0016392120.9983608
ENST00000369557ENST00000308482SLC35A1chr688211028-LRRFIP1chr2238617187+0.0016839110.99831605

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Fusion Genomic Features for SLC35A1-LRRFIP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for SLC35A1-LRRFIP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:88211028/chr2:238617187)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48101_102169338.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48117_124169338.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47101_102169279.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47117_124169279.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48109_114169338.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48136_141169338.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-481_9169338.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-4831_45169338.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-4865_87169338.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47109_114169279.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47136_141169279.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-471_9169279.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-4731_45169279.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-4765_87169279.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-4810_30169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48115_135169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48142_160169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-4846_64169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-4888_108169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-4710_30169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47115_135169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47142_160169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-4746_64169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-4788_108169279.0TransmembraneHelical
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000244815010128_25022785.0Coiled coilOntology_term=ECO:0000269
TgeneLRRFIP1chr6:88211028chr2:238617187ENST0000028917508128_25022753.0Coiled coilOntology_term=ECO:0000269
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000308482024128_25032641.0Coiled coilOntology_term=ECO:0000269
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000392000011128_25022809.0Coiled coilOntology_term=ECO:0000269
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000244815010567_59322785.0Compositional biasNote=Lys-rich
TgeneLRRFIP1chr6:88211028chr2:238617187ENST0000028917508567_59322753.0Compositional biasNote=Lys-rich
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000308482024567_59332641.0Compositional biasNote=Lys-rich
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000392000011567_59322809.0Compositional biasNote=Lys-rich
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000244815010485_58422785.0RegionNote=DNA-binding
TgeneLRRFIP1chr6:88211028chr2:238617187ENST0000028917508485_58422753.0RegionNote=DNA-binding
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000308482024485_58432641.0RegionNote=DNA-binding
TgeneLRRFIP1chr6:88211028chr2:238617187ENST00000392000011485_58422809.0RegionNote=DNA-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48210_214169338.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48316_337169338.0RegionIntrinsically disordered
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47210_214169279.0RegionCMP-sialic acid binding
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47316_337169279.0RegionIntrinsically disordered
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48161_175169338.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48197_209169338.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48229_243169338.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48263_269169338.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48289_296169338.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47161_175169279.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47197_209169279.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47229_243169279.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47263_269169279.0Topological domainCytoplasmic
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47289_296169279.0Topological domainLumenal
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48176_196169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48210_228169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48244_262169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48270_288169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369552-48297_315169338.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47176_196169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47210_228169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47244_262169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47270_288169279.0TransmembraneHelical
HgeneSLC35A1chr6:88211028chr2:238617187ENST00000369556-47297_315169279.0TransmembraneHelical


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Fusion Gene Sequence for SLC35A1-LRRFIP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>82933_82933_1_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369552_LRRFIP1_chr2_238617187_ENST00000308482_length(transcript)=3144nt_BP=534nt
AGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCCGAGAGACAATGTCACTTTATTATTCAAGTTATACTGCTTGGCAGTGATGACC
CTGATGGCTGCAGTCTATACCATAGCTTTAAGATACACAAGGACATCAGACAAAGAACTCTACTTTTCAACCACAGCCGTGTGTATCACA
GAAGTTATAAAGTTATTGCTAAGTGTGGGAATTTTAGCTAAAGAAACTGGTAGTCTGGGTAGATTCAAAGCATCTTTAAGAGAAAATGTC
TTGGGGAGCCCCAAGGAACTGTTGAAGTTAAGTGTGCCATCGTTAGTGTATGCTGTTCAGAACAACATGGCTTTCCTAGCTCTTAGCAAT
CTGGATGCAGCAGTGTACCAGGTGACCTACCAGTTGAAGATTCCGTGTACTGCTTTATGCACTGTTTTAATGTTAAACCGGACACTCAGC
AAATTACAGTGGGTTTCAGTTTTTATGCTGTGTGCTGGAGTTACGCTTGTACAGTGGAAACCAGCCCAAGCTACAAAAGTGGTGGCGGAA
GCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGCTCGCGAGATCCGCATGAAGGAGCTGGAGCGGCAGCAGAAGGAGATCTATCAG
GTCCAAAAGAAATATTATGGGCTGGATACAAAATGGGGTGACATCGAGCAGTGGATGGAAGACAGTGAGCGCTACTCTCGTAGATCCAGA
AGAAACACATCGGCTTCTGATGAAGACGAGCGCATGTCAGTGGGTAGTCGTGGAAGCCTGAGGTCGCAGCCTGACTTGGAGTATGGGGGT
CCTTACGCCTGGACAAATGGTTATGATGGAGAATTGTATGGATCACAGTCCCTGAATAGAAGATCTGGCAGGCCCTCCTGTCTGTACAGC
GCTGCCCGGCCTTCGGGGAGTTACCGGGCGTCTGTGTTGGATGAAGGCAGCTTCGGTGGGACCCGACGGGGCAGCACCTCCGGCTCCCGT
GCTCCCTCGGAGTACAGCGGCCACCTCAACTCCAGCTCCCGCGCCTCCTCCAGGGCCAGCTCGGCCCGGGCCAGCCCTGTGGTAGAAGAG
AGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAACATGCCGGGCCTGTCTGCAGCCACGCTGGCCTCTCTGGGTGGGACTTCCTCT
CGGAGAGGCAGCGGAGACACCTCCATCTCCATCGACACCGAGGCATCCATCAGGGAAATCAAGGAACTCAATGAGTTAAAGGACCAGATT
CAGGATGTAGAAGGCAAATACATGCAGGGATTGAAAGAGATGAAGGACTCTCTAGCAGAAGTTGAAGAGAAATATAAGAAGGCTATGGTT
TCCAATGCTCAGCTAGACAATGAAAAGACAAACTTCATGTACCAGGTTGATACCCTAAAAGATATGTTGCTGGAGCTTGAAGAACAGCTG
GCTGAATCTAGGCGGCAGTACGAAGAGAAAAACAAAGAATTTGAAAGGGAAAAACACGCCCACAGTATACTGCAATTTCAGTTTGCTGAA
GTCAAGGAGGCCCTGAAGCAAAGAGAGGAAATGCTCGAGGAAATCCGACAGCTACAGCAGAAACAGGCGAGTTCTATCAGGGAGATTTCT
GATCTTCAGGAAACAATAGAGTGGAAAGACAAAAAGATAGGGGCATTAGAGAGGCAGAAAGAGTTCTTTGATTCCGTAAGGAGTGAACGG
GATGATCTTAGAGAAGAAGTAGTCATGCTGAAAGAGGAATTAAAGAAACATGGAATAATCCTAAATTCAGAAATAGCTACCAATGGAGAG
ACTTCCGACACCCTCAATAATGTTGGATACCAAGGTCCTACCAAGATGACAAAAGAAGAGTTAAATGCCCTCAAGTCGACAGGGGATGGG
ACCCTAGATATTAGGTTGAAAAAGCTGGTTGATGAACGGGAATGCTTATTGGAACAGATTAAGAAACTCAAAGGGCAGCTGGAGGAGAGA
CAGAAGATTGGCAAACTAGACAATCTTCGATCTGAAGATGATGTCTTGGAAAACGGGACAGACATGCATGTAATGGACCTACAAAGGGAT
GCCAACAGACAGATCAGCGACCTCAAATTTAAACTTGCAAAATCTGAGCAAGAGATAACTGCATTAGAACAAAATGTAATAAGGTTAGAG
AGTCAAGTATCACGTTACAAATCAGCGGCTGAAAATGCAGAAAAAATAGAAGATGAACTTAAGGCAGAAAAACGGAAACTCCAAAGAGAG
CTCCGCTCTGCATTGGATAAAACAGAAGAGCTCGAGGTGAGCAACGGCCACTTAGTGAAGCGTCTGGAAAAAATGAAAGCAAATCGGAGT
GCACTCTTGTCCCAGCAGTAAATTCCAGCTCTGATCAGGCAACTGGTTGGTGACTGGAGAGCATTGTTTCATAGGCTTTTCTCTGTCCTA
TCTGGGAGCGCTGCTTCTTCCCCTGCCTTCCGAGAGACGAAGACCGTGGCGAGCTTGGCGCTTAGGGGCTCCCGTGCCATGGCTCACCCC
AGGGAGCCCCAGCAGCCACCAGGTGCCTCTGTCTGCAGACCCCTGGCCCGGGCTGGCGCCGACGCTCAGAACCTGCAGGTACTTCATAAG
CACACAGGGGCCTCGAGGGAGCTCTGTGTCTGACCGCACAGCAGCCTCTGAATGCCGCTGGAAGTGATGATCAAAGTAAAGATTCAGTTG
GGACTTGAGTTTTTTTTTTTTTTCATGTGTCTTGCTGAAGATTAAGGGGAAATGTTACAGTGTTGGGACTTCCTTTCATGGCAGAATCTA
CAATTTGAGCGACTTCAGTAGTATCTCTTAGTCTACGCTTTTCATACACAAAACACTGTGGAACCACAAGCCATTACCAAGCAAAACTCT
TTCACTGGAAACAAGGGGGCAGTCTAGAAGTAAAAGTGACCTTAAGAAGACTCTTTACAGGCAACAAATGAAGCTTTTCTAAGGGATTTT
TGCATCAGTTCAGTCATAAGAATACTTTTTTCCAGGGTAATTAGGCAATAGCTTCACTGAAAATGACAGCTTTTCATTGCATTATTTAAT

>82933_82933_1_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369552_LRRFIP1_chr2_238617187_ENST00000308482_length(amino acids)=777AA_BP=169
MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLK
LSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVAEARLAAKRAA
RAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDLEYGGPYAWTNGYD
GELYGSQSLNRRSGRPSCLYSAARPSGSYRASVLDEGSFGGTRRGSTSGSRAPSEYSGHLNSSSRASSRASSARASPVVEERPEKDFTEK
GSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEK
TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWK
DKKIGALERQKEFFDSVRSERDDLREEVVMLKEELKKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL
VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA

--------------------------------------------------------------
>82933_82933_2_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369556_LRRFIP1_chr2_238617187_ENST00000308482_length(transcript)=3196nt_BP=586nt
ACAAGGGGCGGTCCCCGGTGTCCTGCGCGGGGGCGCGGAGGGGGCGGGCGTCAGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCC
GAGAGACAATGTCACTTTATTATTCAAGTTATACTGCTTGGCAGTGATGACCCTGATGGCTGCAGTCTATACCATAGCTTTAAGATACAC
AAGGACATCAGACAAAGAACTCTACTTTTCAACCACAGCCGTGTGTATCACAGAAGTTATAAAGTTATTGCTAAGTGTGGGAATTTTAGC
TAAAGAAACTGGTAGTCTGGGTAGATTCAAAGCATCTTTAAGAGAAAATGTCTTGGGGAGCCCCAAGGAACTGTTGAAGTTAAGTGTGCC
ATCGTTAGTGTATGCTGTTCAGAACAACATGGCTTTCCTAGCTCTTAGCAATCTGGATGCAGCAGTGTACCAGGTGACCTACCAGTTGAA
GATTCCGTGTACTGCTTTATGCACTGTTTTAATGTTAAACCGGACACTCAGCAAATTACAGTGGGTTTCAGTTTTTATGCTGTGTGCTGG
AGTTACGCTTGTACAGTGGAAACCAGCCCAAGCTACAAAAGTGGTGGCGGAAGCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGC
TCGCGAGATCCGCATGAAGGAGCTGGAGCGGCAGCAGAAGGAGATCTATCAGGTCCAAAAGAAATATTATGGGCTGGATACAAAATGGGG
TGACATCGAGCAGTGGATGGAAGACAGTGAGCGCTACTCTCGTAGATCCAGAAGAAACACATCGGCTTCTGATGAAGACGAGCGCATGTC
AGTGGGTAGTCGTGGAAGCCTGAGGTCGCAGCCTGACTTGGAGTATGGGGGTCCTTACGCCTGGACAAATGGTTATGATGGAGAATTGTA
TGGATCACAGTCCCTGAATAGAAGATCTGGCAGGCCCTCCTGTCTGTACAGCGCTGCCCGGCCTTCGGGGAGTTACCGGGCGTCTGTGTT
GGATGAAGGCAGCTTCGGTGGGACCCGACGGGGCAGCACCTCCGGCTCCCGTGCTCCCTCGGAGTACAGCGGCCACCTCAACTCCAGCTC
CCGCGCCTCCTCCAGGGCCAGCTCGGCCCGGGCCAGCCCTGTGGTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAA
CATGCCGGGCCTGTCTGCAGCCACGCTGGCCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGCGGAGACACCTCCATCTCCATCGACAC
CGAGGCATCCATCAGGGAAATCAAGGAACTCAATGAGTTAAAGGACCAGATTCAGGATGTAGAAGGCAAATACATGCAGGGATTGAAAGA
GATGAAGGACTCTCTAGCAGAAGTTGAAGAGAAATATAAGAAGGCTATGGTTTCCAATGCTCAGCTAGACAATGAAAAGACAAACTTCAT
GTACCAGGTTGATACCCTAAAAGATATGTTGCTGGAGCTTGAAGAACAGCTGGCTGAATCTAGGCGGCAGTACGAAGAGAAAAACAAAGA
ATTTGAAAGGGAAAAACACGCCCACAGTATACTGCAATTTCAGTTTGCTGAAGTCAAGGAGGCCCTGAAGCAAAGAGAGGAAATGCTCGA
GGAAATCCGACAGCTACAGCAGAAACAGGCGAGTTCTATCAGGGAGATTTCTGATCTTCAGGAAACAATAGAGTGGAAAGACAAAAAGAT
AGGGGCATTAGAGAGGCAGAAAGAGTTCTTTGATTCCGTAAGGAGTGAACGGGATGATCTTAGAGAAGAAGTAGTCATGCTGAAAGAGGA
ATTAAAGAAACATGGAATAATCCTAAATTCAGAAATAGCTACCAATGGAGAGACTTCCGACACCCTCAATAATGTTGGATACCAAGGTCC
TACCAAGATGACAAAAGAAGAGTTAAATGCCCTCAAGTCGACAGGGGATGGGACCCTAGATATTAGGTTGAAAAAGCTGGTTGATGAACG
GGAATGCTTATTGGAACAGATTAAGAAACTCAAAGGGCAGCTGGAGGAGAGACAGAAGATTGGCAAACTAGACAATCTTCGATCTGAAGA
TGATGTCTTGGAAAACGGGACAGACATGCATGTAATGGACCTACAAAGGGATGCCAACAGACAGATCAGCGACCTCAAATTTAAACTTGC
AAAATCTGAGCAAGAGATAACTGCATTAGAACAAAATGTAATAAGGTTAGAGAGTCAAGTATCACGTTACAAATCAGCGGCTGAAAATGC
AGAAAAAATAGAAGATGAACTTAAGGCAGAAAAACGGAAACTCCAAAGAGAGCTCCGCTCTGCATTGGATAAAACAGAAGAGCTCGAGGT
GAGCAACGGCCACTTAGTGAAGCGTCTGGAAAAAATGAAAGCAAATCGGAGTGCACTCTTGTCCCAGCAGTAAATTCCAGCTCTGATCAG
GCAACTGGTTGGTGACTGGAGAGCATTGTTTCATAGGCTTTTCTCTGTCCTATCTGGGAGCGCTGCTTCTTCCCCTGCCTTCCGAGAGAC
GAAGACCGTGGCGAGCTTGGCGCTTAGGGGCTCCCGTGCCATGGCTCACCCCAGGGAGCCCCAGCAGCCACCAGGTGCCTCTGTCTGCAG
ACCCCTGGCCCGGGCTGGCGCCGACGCTCAGAACCTGCAGGTACTTCATAAGCACACAGGGGCCTCGAGGGAGCTCTGTGTCTGACCGCA
CAGCAGCCTCTGAATGCCGCTGGAAGTGATGATCAAAGTAAAGATTCAGTTGGGACTTGAGTTTTTTTTTTTTTTCATGTGTCTTGCTGA
AGATTAAGGGGAAATGTTACAGTGTTGGGACTTCCTTTCATGGCAGAATCTACAATTTGAGCGACTTCAGTAGTATCTCTTAGTCTACGC
TTTTCATACACAAAACACTGTGGAACCACAAGCCATTACCAAGCAAAACTCTTTCACTGGAAACAAGGGGGCAGTCTAGAAGTAAAAGTG
ACCTTAAGAAGACTCTTTACAGGCAACAAATGAAGCTTTTCTAAGGGATTTTTGCATCAGTTCAGTCATAAGAATACTTTTTTCCAGGGT
AATTAGGCAATAGCTTCACTGAAAATGACAGCTTTTCATTGCATTATTTAATCCTTATATTTGGAATTGAAGTCGTTAACTTCTTTTAAA

>82933_82933_2_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369556_LRRFIP1_chr2_238617187_ENST00000308482_length(amino acids)=796AA_BP=188
MRGGAEGAGVSSAGGCRGTMAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLG
RFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWK
PAQATKVVAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSL
RSQPDLEYGGPYAWTNGYDGELYGSQSLNRRSGRPSCLYSAARPSGSYRASVLDEGSFGGTRRGSTSGSRAPSEYSGHLNSSSRASSRAS
SARASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAE
VEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQ
KQASSIREISDLQETIEWKDKKIGALERQKEFFDSVRSERDDLREEVVMLKEELKKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEE
LNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEIT

--------------------------------------------------------------
>82933_82933_3_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369557_LRRFIP1_chr2_238617187_ENST00000308482_length(transcript)=3117nt_BP=507nt
ATGGCTGCCCCGAGAGACAATGTCACTTTATTATTCAAGTTATACTGCTTGGCAGTGATGACCCTGATGGCTGCAGTCTATACCATAGCT
TTAAGATACACAAGGACATCAGACAAAGAACTCTACTTTTCAACCACAGCCGTGTGTATCACAGAAGTTATAAAGTTATTGCTAAGTGTG
GGAATTTTAGCTAAAGAAACTGGTAGTCTGGGTAGATTCAAAGCATCTTTAAGAGAAAATGTCTTGGGGAGCCCCAAGGAACTGTTGAAG
TTAAGTGTGCCATCGTTAGTGTATGCTGTTCAGAACAACATGGCTTTCCTAGCTCTTAGCAATCTGGATGCAGCAGTGTACCAGGTGACC
TACCAGTTGAAGATTCCGTGTACTGCTTTATGCACTGTTTTAATGTTAAACCGGACACTCAGCAAATTACAGTGGGTTTCAGTTTTTATG
CTGTGTGCTGGAGTTACGCTTGTACAGTGGAAACCAGCCCAAGCTACAAAAGTGGTGGCGGAAGCCCGGCTCGCTGCAAAACGGGCGGCC
CGCGCGGAGGCTCGCGAGATCCGCATGAAGGAGCTGGAGCGGCAGCAGAAGGAGATCTATCAGGTCCAAAAGAAATATTATGGGCTGGAT
ACAAAATGGGGTGACATCGAGCAGTGGATGGAAGACAGTGAGCGCTACTCTCGTAGATCCAGAAGAAACACATCGGCTTCTGATGAAGAC
GAGCGCATGTCAGTGGGTAGTCGTGGAAGCCTGAGGTCGCAGCCTGACTTGGAGTATGGGGGTCCTTACGCCTGGACAAATGGTTATGAT
GGAGAATTGTATGGATCACAGTCCCTGAATAGAAGATCTGGCAGGCCCTCCTGTCTGTACAGCGCTGCCCGGCCTTCGGGGAGTTACCGG
GCGTCTGTGTTGGATGAAGGCAGCTTCGGTGGGACCCGACGGGGCAGCACCTCCGGCTCCCGTGCTCCCTCGGAGTACAGCGGCCACCTC
AACTCCAGCTCCCGCGCCTCCTCCAGGGCCAGCTCGGCCCGGGCCAGCCCTGTGGTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAG
GGGTCTCGTAACATGCCGGGCCTGTCTGCAGCCACGCTGGCCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGCGGAGACACCTCCATC
TCCATCGACACCGAGGCATCCATCAGGGAAATCAAGGAACTCAATGAGTTAAAGGACCAGATTCAGGATGTAGAAGGCAAATACATGCAG
GGATTGAAAGAGATGAAGGACTCTCTAGCAGAAGTTGAAGAGAAATATAAGAAGGCTATGGTTTCCAATGCTCAGCTAGACAATGAAAAG
ACAAACTTCATGTACCAGGTTGATACCCTAAAAGATATGTTGCTGGAGCTTGAAGAACAGCTGGCTGAATCTAGGCGGCAGTACGAAGAG
AAAAACAAAGAATTTGAAAGGGAAAAACACGCCCACAGTATACTGCAATTTCAGTTTGCTGAAGTCAAGGAGGCCCTGAAGCAAAGAGAG
GAAATGCTCGAGGAAATCCGACAGCTACAGCAGAAACAGGCGAGTTCTATCAGGGAGATTTCTGATCTTCAGGAAACAATAGAGTGGAAA
GACAAAAAGATAGGGGCATTAGAGAGGCAGAAAGAGTTCTTTGATTCCGTAAGGAGTGAACGGGATGATCTTAGAGAAGAAGTAGTCATG
CTGAAAGAGGAATTAAAGAAACATGGAATAATCCTAAATTCAGAAATAGCTACCAATGGAGAGACTTCCGACACCCTCAATAATGTTGGA
TACCAAGGTCCTACCAAGATGACAAAAGAAGAGTTAAATGCCCTCAAGTCGACAGGGGATGGGACCCTAGATATTAGGTTGAAAAAGCTG
GTTGATGAACGGGAATGCTTATTGGAACAGATTAAGAAACTCAAAGGGCAGCTGGAGGAGAGACAGAAGATTGGCAAACTAGACAATCTT
CGATCTGAAGATGATGTCTTGGAAAACGGGACAGACATGCATGTAATGGACCTACAAAGGGATGCCAACAGACAGATCAGCGACCTCAAA
TTTAAACTTGCAAAATCTGAGCAAGAGATAACTGCATTAGAACAAAATGTAATAAGGTTAGAGAGTCAAGTATCACGTTACAAATCAGCG
GCTGAAAATGCAGAAAAAATAGAAGATGAACTTAAGGCAGAAAAACGGAAACTCCAAAGAGAGCTCCGCTCTGCATTGGATAAAACAGAA
GAGCTCGAGGTGAGCAACGGCCACTTAGTGAAGCGTCTGGAAAAAATGAAAGCAAATCGGAGTGCACTCTTGTCCCAGCAGTAAATTCCA
GCTCTGATCAGGCAACTGGTTGGTGACTGGAGAGCATTGTTTCATAGGCTTTTCTCTGTCCTATCTGGGAGCGCTGCTTCTTCCCCTGCC
TTCCGAGAGACGAAGACCGTGGCGAGCTTGGCGCTTAGGGGCTCCCGTGCCATGGCTCACCCCAGGGAGCCCCAGCAGCCACCAGGTGCC
TCTGTCTGCAGACCCCTGGCCCGGGCTGGCGCCGACGCTCAGAACCTGCAGGTACTTCATAAGCACACAGGGGCCTCGAGGGAGCTCTGT
GTCTGACCGCACAGCAGCCTCTGAATGCCGCTGGAAGTGATGATCAAAGTAAAGATTCAGTTGGGACTTGAGTTTTTTTTTTTTTTCATG
TGTCTTGCTGAAGATTAAGGGGAAATGTTACAGTGTTGGGACTTCCTTTCATGGCAGAATCTACAATTTGAGCGACTTCAGTAGTATCTC
TTAGTCTACGCTTTTCATACACAAAACACTGTGGAACCACAAGCCATTACCAAGCAAAACTCTTTCACTGGAAACAAGGGGGCAGTCTAG
AAGTAAAAGTGACCTTAAGAAGACTCTTTACAGGCAACAAATGAAGCTTTTCTAAGGGATTTTTGCATCAGTTCAGTCATAAGAATACTT
TTTTCCAGGGTAATTAGGCAATAGCTTCACTGAAAATGACAGCTTTTCATTGCATTATTTAATCCTTATATTTGGAATTGAAGTCGTTAA

>82933_82933_3_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000369557_LRRFIP1_chr2_238617187_ENST00000308482_length(amino acids)=777AA_BP=169
MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLK
LSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVAEARLAAKRAA
RAEAREIRMKELERQQKEIYQVQKKYYGLDTKWGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDLEYGGPYAWTNGYD
GELYGSQSLNRRSGRPSCLYSAARPSGSYRASVLDEGSFGGTRRGSTSGSRAPSEYSGHLNSSSRASSRASSARASPVVEERPEKDFTEK
GSRNMPGLSAATLASLGGTSSRRGSGDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEK
TNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWK
DKKIGALERQKEFFDSVRSERDDLREEVVMLKEELKKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKL
VDERECLLEQIKKLKGQLEERQKIGKLDNLRSEDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSA

--------------------------------------------------------------
>82933_82933_4_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000544441_LRRFIP1_chr2_238617187_ENST00000308482_length(transcript)=2987nt_BP=377nt
GTCAGTTCCGCGGGGGGCTGTCGGGGAACCATGGCTGCCCCGAGAGACAATGTCACTTTATTATTCAAGTTATACTGCTTGGCAGTGATG
ACCCTGATGGCTGCAGTCTATACCATAGCTTTAAGATACACAAGGACATCAGACAAAGAACTCTACTTTTCAACCACAGCCGTGTGTATC
ACAGAAGTTATAAAGTTATTGCTAAGTGTGGGAATTTTAGCTAAGTGACCTACCAGTTGAAGATTCCGTGTACTGCTTTATGCACTGTTT
TAATGTTAAACCGGACACTCAGCAAATTACAGTGGGTTTCAGTTTTTATGCTGTGTGCTGGAGTTACGCTTGTACAGTGGAAACCAGCCC
AAGCTACAAAAGTGGTGGCGGAAGCCCGGCTCGCTGCAAAACGGGCGGCCCGCGCGGAGGCTCGCGAGATCCGCATGAAGGAGCTGGAGC
GGCAGCAGAAGGAGATCTATCAGGTCCAAAAGAAATATTATGGGCTGGATACAAAATGGGGTGACATCGAGCAGTGGATGGAAGACAGTG
AGCGCTACTCTCGTAGATCCAGAAGAAACACATCGGCTTCTGATGAAGACGAGCGCATGTCAGTGGGTAGTCGTGGAAGCCTGAGGTCGC
AGCCTGACTTGGAGTATGGGGGTCCTTACGCCTGGACAAATGGTTATGATGGAGAATTGTATGGATCACAGTCCCTGAATAGAAGATCTG
GCAGGCCCTCCTGTCTGTACAGCGCTGCCCGGCCTTCGGGGAGTTACCGGGCGTCTGTGTTGGATGAAGGCAGCTTCGGTGGGACCCGAC
GGGGCAGCACCTCCGGCTCCCGTGCTCCCTCGGAGTACAGCGGCCACCTCAACTCCAGCTCCCGCGCCTCCTCCAGGGCCAGCTCGGCCC
GGGCCAGCCCTGTGGTAGAAGAGAGACCAGAAAAAGATTTTACTGAGAAGGGGTCTCGTAACATGCCGGGCCTGTCTGCAGCCACGCTGG
CCTCTCTGGGTGGGACTTCCTCTCGGAGAGGCAGCGGAGACACCTCCATCTCCATCGACACCGAGGCATCCATCAGGGAAATCAAGGAAC
TCAATGAGTTAAAGGACCAGATTCAGGATGTAGAAGGCAAATACATGCAGGGATTGAAAGAGATGAAGGACTCTCTAGCAGAAGTTGAAG
AGAAATATAAGAAGGCTATGGTTTCCAATGCTCAGCTAGACAATGAAAAGACAAACTTCATGTACCAGGTTGATACCCTAAAAGATATGT
TGCTGGAGCTTGAAGAACAGCTGGCTGAATCTAGGCGGCAGTACGAAGAGAAAAACAAAGAATTTGAAAGGGAAAAACACGCCCACAGTA
TACTGCAATTTCAGTTTGCTGAAGTCAAGGAGGCCCTGAAGCAAAGAGAGGAAATGCTCGAGGAAATCCGACAGCTACAGCAGAAACAGG
CGAGTTCTATCAGGGAGATTTCTGATCTTCAGGAAACAATAGAGTGGAAAGACAAAAAGATAGGGGCATTAGAGAGGCAGAAAGAGTTCT
TTGATTCCGTAAGGAGTGAACGGGATGATCTTAGAGAAGAAGTAGTCATGCTGAAAGAGGAATTAAAGAAACATGGAATAATCCTAAATT
CAGAAATAGCTACCAATGGAGAGACTTCCGACACCCTCAATAATGTTGGATACCAAGGTCCTACCAAGATGACAAAAGAAGAGTTAAATG
CCCTCAAGTCGACAGGGGATGGGACCCTAGATATTAGGTTGAAAAAGCTGGTTGATGAACGGGAATGCTTATTGGAACAGATTAAGAAAC
TCAAAGGGCAGCTGGAGGAGAGACAGAAGATTGGCAAACTAGACAATCTTCGATCTGAAGATGATGTCTTGGAAAACGGGACAGACATGC
ATGTAATGGACCTACAAAGGGATGCCAACAGACAGATCAGCGACCTCAAATTTAAACTTGCAAAATCTGAGCAAGAGATAACTGCATTAG
AACAAAATGTAATAAGGTTAGAGAGTCAAGTATCACGTTACAAATCAGCGGCTGAAAATGCAGAAAAAATAGAAGATGAACTTAAGGCAG
AAAAACGGAAACTCCAAAGAGAGCTCCGCTCTGCATTGGATAAAACAGAAGAGCTCGAGGTGAGCAACGGCCACTTAGTGAAGCGTCTGG
AAAAAATGAAAGCAAATCGGAGTGCACTCTTGTCCCAGCAGTAAATTCCAGCTCTGATCAGGCAACTGGTTGGTGACTGGAGAGCATTGT
TTCATAGGCTTTTCTCTGTCCTATCTGGGAGCGCTGCTTCTTCCCCTGCCTTCCGAGAGACGAAGACCGTGGCGAGCTTGGCGCTTAGGG
GCTCCCGTGCCATGGCTCACCCCAGGGAGCCCCAGCAGCCACCAGGTGCCTCTGTCTGCAGACCCCTGGCCCGGGCTGGCGCCGACGCTC
AGAACCTGCAGGTACTTCATAAGCACACAGGGGCCTCGAGGGAGCTCTGTGTCTGACCGCACAGCAGCCTCTGAATGCCGCTGGAAGTGA
TGATCAAAGTAAAGATTCAGTTGGGACTTGAGTTTTTTTTTTTTTTCATGTGTCTTGCTGAAGATTAAGGGGAAATGTTACAGTGTTGGG
ACTTCCTTTCATGGCAGAATCTACAATTTGAGCGACTTCAGTAGTATCTCTTAGTCTACGCTTTTCATACACAAAACACTGTGGAACCAC
AAGCCATTACCAAGCAAAACTCTTTCACTGGAAACAAGGGGGCAGTCTAGAAGTAAAAGTGACCTTAAGAAGACTCTTTACAGGCAACAA
ATGAAGCTTTTCTAAGGGATTTTTGCATCAGTTCAGTCATAAGAATACTTTTTTCCAGGGTAATTAGGCAATAGCTTCACTGAAAATGAC
AGCTTTTCATTGCATTATTTAATCCTTATATTTGGAATTGAAGTCGTTAACTTCTTTTAAAGAATGTACTATTAGAAAAATTAAAAATGA

>82933_82933_4_SLC35A1-LRRFIP1_SLC35A1_chr6_88211028_ENST00000544441_LRRFIP1_chr2_238617187_ENST00000308482_length(amino acids)=655AA_BP=47
MKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVAEARLAAKRAARAEAREIRMKELERQQKEIYQVQKKYYGLDTK
WGDIEQWMEDSERYSRRSRRNTSASDEDERMSVGSRGSLRSQPDLEYGGPYAWTNGYDGELYGSQSLNRRSGRPSCLYSAARPSGSYRAS
VLDEGSFGGTRRGSTSGSRAPSEYSGHLNSSSRASSRASSARASPVVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGSGDTSISI
DTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQLDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKN
KEFEREKHAHSILQFQFAEVKEALKQREEMLEEIRQLQQKQASSIREISDLQETIEWKDKKIGALERQKEFFDSVRSERDDLREEVVMLK
EELKKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLDIRLKKLVDERECLLEQIKKLKGQLEERQKIGKLDNLRS
EDDVLENGTDMHVMDLQRDANRQISDLKFKLAKSEQEITALEQNVIRLESQVSRYKSAAENAEKIEDELKAEKRKLQRELRSALDKTEEL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SLC35A1-LRRFIP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SLC35A1-LRRFIP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC35A1-LRRFIP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC35A1C1970344Congenital Disorder Of Glycosylation, Type IIF3CTD_human;GENOMICS_ENGLAND
HgeneSLC35A1C0019080Hemorrhage1GENOMICS_ENGLAND
HgeneSLC35A1C0036572Seizures1GENOMICS_ENGLAND
HgeneSLC35A1C2751260Macrothrombocytopenia1GENOMICS_ENGLAND
HgeneSLC35A1C4317224Congenital disorder of glycosylation type 1q1GENOMICS_ENGLAND
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human