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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SEC31A-ALK (FusionGDB2 ID:HG22872TG238)

Fusion Gene Summary for SEC31A-ALK

check button Fusion gene summary
Fusion gene informationFusion gene name: SEC31A-ALK
Fusion gene ID: hg22872tg238
HgeneTgene
Gene symbol

SEC31A

ALK

Gene ID

22872

238

Gene nameSEC31 homolog A, COPII coat complex componentALK receptor tyrosine kinase
SynonymsABP125|ABP130|HSPC275|HSPC334|NEDSOSB|SEC31L1CD246|NBLST3
Cytomap('SEC31A')('ALK')

4q21.22

2p23.2-p23.1

Type of geneprotein-codingprotein-coding
Descriptionprotein transport protein Sec31ASEC31 homolog A, COPII coating complex componentSEC31-like protein 1SEC31-related protein Aweb1-like proteinyeast Sec31p homologALK tyrosine kinase receptorCD246 antigenanaplastic lymphoma receptor tyrosine kinasemutant anaplastic lymphoma kinase
Modification date2020031320200329
UniProtAcc

O94979

Q9UM73

Ensembl transtripts involved in fusion geneENST00000264405, ENST00000311785, 
ENST00000326950, ENST00000348405, 
ENST00000355196, ENST00000395310, 
ENST00000432794, ENST00000443462, 
ENST00000448323, ENST00000500777, 
ENST00000505472, ENST00000505984, 
ENST00000508479, ENST00000508502, 
ENST00000509142, ENST00000513858, 
ENST00000436790, 
Fusion gene scores* DoF score22 X 23 X 10=506056 X 74 X 20=82880
# samples 2557
** MAII scorelog2(25/5060*10)=-4.33913738491959
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(57/82880*10)=-7.18391827352181
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SEC31A [Title/Abstract] AND ALK [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSEC31A(83765539)-ALK(29446394), # samples:1
Anticipated loss of major functional domain due to fusion event.SEC31A-ALK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SEC31A-ALK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SEC31A-ALK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SEC31A-ALK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SEC31A-ALK seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
SEC31A-ALK seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
SEC31A-ALK seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
SEC31A-ALK seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSEC31A

GO:0051592

response to calcium ion

17196169

HgeneSEC31A

GO:0090110

cargo loading into COPII-coated vesicle

17499046|18843296

TgeneALK

GO:0016310

phosphorylation

9174053

TgeneALK

GO:0046777

protein autophosphorylation

9174053


check buttonFusion gene breakpoints across SEC31A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ALK (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..SEC31Achr4

83763292

-ALKchr2

29445473

-
ChimerKB3..SEC31Achr4

83763292

-ALKchr2

29446394

-
ChimerKB3..SEC31Achr4

83769956

-ALKchr2

29446394

-
ChimerKB4..SEC31Achr4

83769956

-ALKchr2

29446394

-
ChiTaRS5.0N/AKJ495955SEC31Achr4

83765539

-ALKchr2

29446394

-


Top

Fusion Gene ORF analysis for SEC31A-ALK

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000264405ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000264405ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000264405ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000264405ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000311785ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000311785ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000311785ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000311785ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000326950ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000326950ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000326950ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000348405ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000348405ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000348405ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000355196ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000355196ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000355196ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000395310ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000395310ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000395310ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000432794ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000432794ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000432794ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000443462ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000443462ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000443462ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000443462ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000448323ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000448323ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000448323ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000500777ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000500777ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000500777ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000500777ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000505472ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
5CDS-intronENST00000505472ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000505472ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000505984ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000505984ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000505984ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000505984ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000508479ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000508479ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000508502ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000508502ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000508502ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000508502ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000509142ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000509142ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000509142ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000509142ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000513858ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000513858ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
5CDS-intronENST00000513858ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
5CDS-intronENST00000513858ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
Frame-shiftENST00000264405ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000311785ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000326950ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000326950ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000348405ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000348405ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000355196ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
Frame-shiftENST00000355196ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
Frame-shiftENST00000395310ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000395310ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000432794ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000432794ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000443462ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000448323ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000448323ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000500777ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000505472ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
Frame-shiftENST00000505472ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000505984ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000508479ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000508502ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000509142ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
Frame-shiftENST00000513858ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
In-frameENST00000264405ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000311785ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000326950ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000326950ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000348405ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000348405ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000355196ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
In-frameENST00000355196ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
In-frameENST00000395310ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000395310ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000432794ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000432794ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000443462ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000448323ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000448323ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000500777ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000505472ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
In-frameENST00000505472ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000505984ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000508502ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000509142ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
In-frameENST00000513858ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-3CDSENST00000264405ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000264405ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000311785ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000311785ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000436790ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000436790ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000436790ENST00000389048SEC31Achr4

83769956

-ALKchr2

29446394

-
intron-3CDSENST00000436790ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-3CDSENST00000443462ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000443462ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000500777ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000500777ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000505984ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000505984ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000508479ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000508479ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000508479ENST00000389048SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-3CDSENST00000508502ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000508502ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000509142ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000509142ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-3CDSENST00000513858ENST00000389048SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-3CDSENST00000513858ENST00000389048SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000264405ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000264405ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000264405ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000264405ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000311785ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000311785ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000311785ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000311785ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000436790ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000431873SEC31Achr4

83769956

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000436790ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000498037SEC31Achr4

83769956

-ALKchr2

29446394

-
intron-intronENST00000436790ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-intronENST00000443462ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000443462ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000443462ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000443462ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000500777ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000500777ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000500777ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000500777ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000505984ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000505984ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000505984ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000505984ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000508479ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000508479ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000508479ENST00000431873SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-intronENST00000508479ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000508479ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000508479ENST00000498037SEC31Achr4

83765539

-ALKchr2

29446394

-
intron-intronENST00000508502ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000508502ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000508502ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000508502ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000509142ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000509142ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000509142ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000509142ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000513858ENST00000431873SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000513858ENST00000431873SEC31Achr4

83763292

-ALKchr2

29446394

-
intron-intronENST00000513858ENST00000498037SEC31Achr4

83763292

-ALKchr2

29445473

-
intron-intronENST00000513858ENST00000498037SEC31Achr4

83763292

-ALKchr2

29446394

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355196SEC31Achr483763292-ENST00000389048ALKchr229445473-5300334637834341018
ENST00000348405SEC31Achr483763292-ENST00000389048ALKchr229446394-504529042945941521
ENST00000395310SEC31Achr483763292-ENST00000389048ALKchr229446394-5292315115948411560
ENST00000326950SEC31Achr483763292-ENST00000389048ALKchr229446394-5153301214047021520
ENST00000432794SEC31Achr483763292-ENST00000389048ALKchr229446394-5273313214048221560
ENST00000448323SEC31Achr483763292-ENST00000389048ALKchr229446394-5270312914048191559
ENST00000505472SEC31Achr483763292-ENST00000389048ALKchr229446394-52033062147521583
ENST00000355196SEC31Achr483769956-ENST00000389048ALKchr229446394-502128803782948856
ENST00000348405SEC31Achr483765539-ENST00000389048ALKchr229446394-470325622942521407
ENST00000513858SEC31Achr483765539-ENST00000389048ALKchr229446394-472025794642691407
ENST00000395310SEC31Achr483765539-ENST00000389048ALKchr229446394-4950280915944991446
ENST00000443462SEC31Achr483765539-ENST00000389048ALKchr229446394-47792638043281442
ENST00000509142SEC31Achr483765539-ENST00000389048ALKchr229446394-4895275410744441445
ENST00000326950SEC31Achr483765539-ENST00000389048ALKchr229446394-4811267014043601406
ENST00000432794SEC31Achr483765539-ENST00000389048ALKchr229446394-4931279014044801446
ENST00000311785SEC31Achr483765539-ENST00000389048ALKchr229446394-4931279014044801446
ENST00000448323SEC31Achr483765539-ENST00000389048ALKchr229446394-4928278714044771445
ENST00000505472SEC31Achr483765539-ENST00000389048ALKchr229446394-48612720144101469
ENST00000500777SEC31Achr483765539-ENST00000389048ALKchr229446394-46542513442031399
ENST00000508502SEC31Achr483765539-ENST00000389048ALKchr229446394-488727469644361446
ENST00000264405SEC31Achr483765539-ENST00000389048ALKchr229446394-4544240348540931202
ENST00000505984SEC31Achr483765539-ENST00000389048ALKchr229446394-471525744142641407

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000348405ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0010988240.9989011
ENST00000513858ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0011209270.998879
ENST00000395310ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0016049820.998395
ENST00000443462ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0012746050.99872535
ENST00000509142ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0014893120.99851066
ENST00000326950ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0012427690.99875724
ENST00000432794ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0016145140.99838555
ENST00000311785ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0016145140.99838555
ENST00000448323ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0015662150.99843377
ENST00000505472ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0010115190.99898845
ENST00000500777ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0009450320.99905497
ENST00000508502ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0014994150.9985006
ENST00000264405ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0012031310.9987968
ENST00000505984ENST00000389048SEC31Achr483765539-ALKchr229446394-0.0011023950.99889755

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Fusion Genomic Features for SEC31A-ALK


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for SEC31A-ALK


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:83765539/chr2:29446394)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SEC31A

O94979

ALK

Q9UM73

FUNCTION: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:10788476). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). {ECO:0000250|UniProtKB:Q9Z2Q1, ECO:0000269|PubMed:10788476}.FUNCTION: Neuronal receptor tyrosine kinase that is essentially and transiently expressed in specific regions of the central and peripheral nervous systems and plays an important role in the genesis and differentiation of the nervous system. Transduces signals from ligands at the cell surface, through specific activation of the mitogen-activated protein kinase (MAPK) pathway. Phosphorylates almost exclusively at the first tyrosine of the Y-x-x-x-Y-Y motif. Following activation by ligand, ALK induces tyrosine phosphorylation of CBL, FRS2, IRS1 and SHC1, as well as of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Acts as a receptor for ligands pleiotrophin (PTN), a secreted growth factor, and midkine (MDK), a PTN-related factor, thus participating in PTN and MDK signal transduction. PTN-binding induces MAPK pathway activation, which is important for the anti-apoptotic signaling of PTN and regulation of cell proliferation. MDK-binding induces phosphorylation of the ALK target insulin receptor substrate (IRS1), activates mitogen-activated protein kinases (MAPKs) and PI3-kinase, resulting also in cell proliferation induction. Drives NF-kappa-B activation, probably through IRS1 and the activation of the AKT serine/threonine kinase. Recruitment of IRS1 to activated ALK and the activation of NF-kappa-B are essential for the autocrine growth and survival signaling of MDK. Thinness gene involved in the resistance to weight gain: in hypothalamic neurons, controls energy expenditure acting as a negative regulator of white adipose tissue lipolysis and sympathetic tone to fine-tune energy homeostasis (By similarity). {ECO:0000250|UniProtKB:P97793, ECO:0000269|PubMed:11121404, ECO:0000269|PubMed:11278720, ECO:0000269|PubMed:11387242, ECO:0000269|PubMed:11809760, ECO:0000269|PubMed:12107166, ECO:0000269|PubMed:12122009, ECO:0000269|PubMed:15226403, ECO:0000269|PubMed:15908427, ECO:0000269|PubMed:16317043, ECO:0000269|PubMed:16878150, ECO:0000269|PubMed:17274988}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126842_8488751107.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329842_8488751221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127842_8488751221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128842_8488751234.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026842_8488701201.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127842_8488751221.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127842_8488751206.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126842_8488751107.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126120_1608751107.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126166_2068751107.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126209_2548751107.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126258_2988751107.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126301_3428751107.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-21264_478751107.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-212668_1118751107.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925120_1608361182.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925166_2068361182.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925209_2548361182.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925258_2988361182.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925301_3428361182.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-19254_478361182.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-192568_1118361182.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925120_1608361182.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925166_2068361182.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925209_2548361182.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925258_2988361182.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925301_3428361182.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-19254_478361182.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-192568_1118361182.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329120_1608751221.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329166_2068751221.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329209_2548751221.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329258_2988751221.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329301_3428751221.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-23294_478751221.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-232968_1118751221.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127120_1608751221.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127166_2068751221.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127209_2548751221.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127258_2988751221.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127301_3428751221.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-21274_478751221.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-212768_1118751221.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128120_1608751234.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128166_2068751234.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128209_2548751234.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128258_2988751234.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128301_3428751234.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-21284_478751234.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-212868_1118751234.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026120_1608701201.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026166_2068701201.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026209_2548701201.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026258_2988701201.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026301_3428701201.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-20264_478701201.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-202668_1118701201.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127120_1608751221.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127166_2068751221.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127209_2548751221.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127258_2988751221.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127301_3428751221.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-21274_478751221.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-212768_1118751221.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823120_1608361068.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823166_2068361068.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823209_2548361068.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823258_2988361068.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823301_3428361068.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-18234_478361068.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-182368_1118361068.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127120_1608751206.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127166_2068751206.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127209_2548751206.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127258_2988751206.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127301_3428751206.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-21274_478751206.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-212768_1118751206.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126120_1608751107.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126166_2068751107.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126209_2548751107.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126258_2988751107.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126301_3428751107.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-21264_478751107.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-212668_1118751107.0RepeatNote=WD 2
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924120_1608361068.0RepeatNote=WD 3
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924166_2068361068.0RepeatNote=WD 4
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924209_2548361068.0RepeatNote=WD 5
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924258_2988361068.0RepeatNote=WD 6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924301_3428361068.0RepeatNote=WD 7
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-19244_478361068.0RepeatNote=WD 1
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-192468_1118361068.0RepeatNote=WD 2
TgeneALKchr4:83765539chr2:29446394ENST0000038904818291116_139210571621.0DomainProtein kinase
TgeneALKchr4:83765539chr2:29446394ENST0000038904818291197_119910571621.0RegionNote=Inhibitor binding
TgeneALKchr4:83765539chr2:29446394ENST0000038904818291060_162010571621.0Topological domainCytoplasmic

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126800_10918751107.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925800_10918361182.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925800_10918361182.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329800_10918751221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127800_10918751221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128800_10918751234.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026800_10918701201.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127800_10918751221.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823800_10918361068.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127800_10918751206.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126800_10918751107.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924800_10918361068.0Compositional biasNote=Pro-rich
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925842_8488361182.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925842_8488361182.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823842_8488361068.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924842_8488361068.0MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneALKchr4:83765539chr2:29446394ENST000003890481829816_94010571621.0Compositional biasNote=Gly-rich
TgeneALKchr4:83765539chr2:29446394ENST000003890481829264_42710571621.0DomainMAM 1
TgeneALKchr4:83765539chr2:29446394ENST000003890481829437_47310571621.0DomainNote=LDL-receptor class A
TgeneALKchr4:83765539chr2:29446394ENST000003890481829478_63610571621.0DomainMAM 2
TgeneALKchr4:83765539chr2:29446394ENST00000389048182919_103810571621.0Topological domainExtracellular
TgeneALKchr4:83765539chr2:29446394ENST0000038904818291039_105910571621.0TransmembraneHelical


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Fusion Gene Sequence for SEC31A-ALK


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80098_80098_1_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000326950_ALK_chr2_29446394_ENST00000389048_length(transcript)=5153nt_BP=3012nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGGATGAAGTTAAAGGAAGTAG
ATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACAT
TTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTC
ACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAA
ATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAG
CCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAA
CCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAG
CCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTT
CTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTC
GATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTAC
TGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCT
TCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTA
GCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTC
CGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTT
CTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATG
TGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATT
ATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTG
GAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCT
CATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTG
TTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAA
AATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATC
TTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGC
TTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGA
CTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAG
CCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAG
CCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAG
GACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAG
TTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTC
AGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCAGCCCAGCCGTATCCCTTCG
GAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTTGCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTG
CTTCTTCCTATACTGGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCTGCTACTTCTTTCCCTCCTC
CCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGAGCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTA
CACTGCCTGCTGCCAGTGAGCTGCCTGCGTCCCAAAGAACAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGC
AGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCT
CCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCC
AGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATT
TCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCA
TCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGC
TGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAA
ACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATA
GAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGT
CCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCA
GTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGC
CCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCAC
TTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGG
AGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTC
GAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACG
GATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAA
AGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCT
CACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATT
ACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATA
GCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGC
TCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCT
TTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGG
TTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGC
TGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATA

>80098_80098_1_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000326950_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1520AA_BP=957
MPKVLARMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKG
DVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISC
IAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGI
LAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF
GNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSD
QLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDGL
ITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKP
DEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQ
YANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPG
FIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQA
SSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMT
DYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIV
RCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGD
FGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYR
IMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSG
KAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCT

--------------------------------------------------------------
>80098_80098_2_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000348405_ALK_chr2_29446394_ENST00000389048_length(transcript)=5045nt_BP=2904nt
GACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGG
CATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCC
TTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGA
TTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATC
CTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTT
TCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAG
CCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGG
CCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATC
CTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCAC
TTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATG
CTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTC
CCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGAC
AGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGC
AGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCA
AACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTG
TAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTG
ATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTC
TAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTA
ATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATG
ATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCC
AAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGG
CTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATA
GCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAA
GCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTG
TAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTG
ACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAA
TTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATT
ATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAG
GTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAA
TGTATCGACCTCAGCAGCCTGTTGCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGC
AGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCAT
CCTTCCAGCATGGCGGACCAGGAGCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTG
AGCTGCCTGCGTCCCAAAGAACAGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGC
TGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGG
AGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCA
ACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGA
TCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGG
CGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGG
CTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTC
CAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCA
TGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTAT
GGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACC
CACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTT
TGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGA
AAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTG
CCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGG
CCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCA
CCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACA
GGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCT
CTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGG
GCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGC
CCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGA
CCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCA
TGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATG
CATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAG
TTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATAAAGGAGTTATTTGTAATG

>80098_80098_2_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000348405_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1521AA_BP=958
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDG
LITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAK
PDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMS
QYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPP
GFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQ
ASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIM
TDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNI
VRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIG
DFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVY
RIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSS
GKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSC

--------------------------------------------------------------
>80098_80098_3_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000355196_ALK_chr2_29445473_ENST00000389048_length(transcript)=5300nt_BP=3346nt
GCGGAATAGTGGGTTTTGCTGCAACCGGTTTATTTTCCTTCTGTTTTCACCCATTCTGGCACAATCTGGCGCCATCGTCCTTCTTGTGAG
GCCAAGCCTGAAAATGCGAAGCAGAGAGGCAGGACCAAAATTGAGGCGAATCCAGGAACCTGCCAATGGGTCTCCGGGTGCGGTCTCTGA
AACTGGAGGATATCGGGAGGAAAGGCTCTCCGATGCGGAGATAATGGGGAAGCTCTTGGCATGGTTGGCTGTAGGTATGTGATACCGGAG
GAGCAGGAGTCAAATAGGATACGCCGACTTTTAATTCAAGGAACCCTTTTCTGAAACACTTTGCCACAATGAAGGAAATAAGATTACAGC
CGAAGATACATATTAAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTA
GCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCC
TTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGAT
GTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTG
ATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAA
TCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATT
GCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATC
ATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAG
GATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTG
GCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAG
GTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTT
GATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGG
AATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAG
AAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCT
CATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAA
CTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGG
TCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATT
GCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCT
GCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCT
GTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGC
ATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAA
ATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCT
GCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTG
CAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCT
TTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTT
CTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACC
AACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTAC
GAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCAT
GGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATG
CACACCCAGGTACCACCTTATCCACAGCCACAGCCTTATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGA
CCTCAGCAGCCTGTTGCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGCAGTCTCAG
CTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCTCCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAG
CATGGCGGACCAGGAGCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTGAGCTGCCT
GCGTCCCAAAGAACAGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCC
TGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCA
ACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCA
AGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCT
GTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAG
TGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGT
GGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTC
TTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCC
CTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAAT
ACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGC
CCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGC
CTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGAC
ACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACC
CAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGC
TGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCA
ATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAG
CCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGC
ACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTT
TGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATT
CTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATA
CTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATG

>80098_80098_3_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000355196_ALK_chr2_29445473_ENST00000389048_length(amino acids)=1018AA_BP=988
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM
ADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQ
SQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLIT
AVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLP
KGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMYRPQQPVA
PPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASELPASQRTG

--------------------------------------------------------------
>80098_80098_4_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000395310_ALK_chr2_29446394_ENST00000389048_length(transcript)=5292nt_BP=3151nt
CGGGGAAAGATGTCGCTCCCGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCT
GGCCGGGGAGGAGGGGCGGCGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGC
AGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCT
GCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCT
TGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTG
ATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGAC
AAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATA
TGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAA
GTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGAC
CATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCA
GTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGC
ATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTT
CCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGT
GTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTT
GGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGG
ATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAG
CAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTG
CAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTA
AACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAAC
AAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTC
TTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATT
GATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATT
ATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATC
ACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTAT
GCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGT
CTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGAT
CTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAG
ATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATC
ATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTC
CCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCA
CCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCA
CCTTATCCACAGCCACAGCCTTATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTT
GCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGCAGTCTCAGCTGTACGCAGCACAG
CACCAGGCCTCTTCACCTACCTCCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGA
GCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTGAGCTGCCTGCGTCCCAAAGAACA
GTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACC
ATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACC
CTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTG
GCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAG
AACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTC
CTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGT
CAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAG
ATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCC
CCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATAT
ATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCT
GTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACC
CAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGAC
CCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACC
TCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAAT
ATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTAC
GGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGA
AGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAG
GAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACT
GCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCAC
TTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGT
GCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAA
AGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTA
TGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTG

>80098_80098_4_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000395310_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1560AA_BP=997
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM
YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASE
LPASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPN
DPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVA
RDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEK
VPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPT
SLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQG

--------------------------------------------------------------
>80098_80098_5_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000432794_ALK_chr2_29446394_ENST00000389048_length(transcript)=5273nt_BP=3132nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAG
TAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAA
CATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTT
CTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATG
GAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGA
GAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTG
CAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCAT
CAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATT
GTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATC
TTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGT
TACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGT
GCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAG
GTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTC
CTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTG
CTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACC
ATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCA
ATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTC
GTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATG
TGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAG
AGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGG
CTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTG
GACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGA
ACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTT
CAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAG
GGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCA
TCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATT
TGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGAC
TTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGAC
CAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGC
ATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGC
CTTATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTTGCTCCTCCTACTTCAAACG
CTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTA
CCTCCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGAGCTCCACCATCATCTTCAG
CTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTGAGCTGCCTGCGTCCCAAAGAACAGTGTACCGCCGGAAGCACC
AGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACC
CCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCC
ATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTG
AAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTG
GGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTC
GCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACC
ACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGG
CCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAG
GAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAA
GCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTC
AGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCA
ACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTC
TCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAA
AGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCA
ACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGA
AACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTA
ACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGC
TACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATT
ACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCC
TAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTA
CCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAA
ATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGT
GTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATG

>80098_80098_5_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000432794_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1560AA_BP=997
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAM
YRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASE
LPASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPN
DPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVA
RDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEK
VPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPT
SLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQG

--------------------------------------------------------------
>80098_80098_6_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000448323_ALK_chr2_29446394_ENST00000389048_length(transcript)=5270nt_BP=3129nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGGATGAAGTTAAAGGAAGTAG
ATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACAT
TTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTC
ACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAA
ATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAG
CCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAA
CCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAG
CCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTT
CTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTC
GATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTAC
TGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCT
TCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTA
GCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTC
CGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTT
CTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATG
TGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATT
ATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTG
GAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGG
CTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGG
AAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTT
TGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGAC
AAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACT
GGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAG
CCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGA
ATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCC
TGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGT
TGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTT
GTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAG
TTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATG
GAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCCTT
ATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGTTGCTCCTCCTACTTCAAACGCTT
ACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGCAGTCTCAGCTGTACGCAGCACAGCACCAGGCCTCTTCACCTACCT
CCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGGAGCTCCACCATCATCTTCAGCTT
ATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTGAGCTGCCTGCGTCCCAAAGAACAGTGTACCGCCGGAAGCACCAGG
AGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCA
ACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATG
GCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAG
TGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGG
TGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCC
CGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACT
TCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCC
GAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAA
TATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCA
ACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGT
GCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACA
CCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCC
TGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGA
AACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACC
CTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAAC
CCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACG
TTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTAC
GTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACG
AGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAA
GACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCA
CCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATG
AGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTG
CTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGC

>80098_80098_6_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000448323_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1559AA_BP=996
MPKVLARMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKG
DVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISC
IAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGI
LAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF
GNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSD
QLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESP
AAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQS
KITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSH
PLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIP
YEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQPYQPAQPYPFGTGGSAMY
RPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPGAPPSSSAYALPPGTTGTLPAASEL
PASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVAR
DIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWE
IFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKV
PVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTS
LWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGL

--------------------------------------------------------------
>80098_80098_7_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000505472_ALK_chr2_29446394_ENST00000389048_length(transcript)=5203nt_BP=3062nt
GATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGC
TCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTG
TGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGAT
TGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAA
GCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATG
GGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGT
TCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCA
TAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGT
GATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCAT
GGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCC
CACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGT
TTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGG
CACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGAT
TCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCA
GCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCA
GTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAA
CTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAA
AGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTT
GGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGA
TGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTAT
ATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCAC
TGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGC
AAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCT
CTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCT
GATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGAT
GAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCAT
GCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCC
CAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGTTAGAATTGCCCCTAC
TGTCACTACCTGGAGTAACAAAACTCCTACTGCCCTTCCCAGCCATCCACCTGCAGCCTCTCCCTCTGACACACAGGGAGAAAATCCTCC
ACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACC
ACCTTATCCACAGCCACAGCCTTATCAACCAGCCCAGCCGTATCCCTTCGGAACAGGGGGGTCAGCAATGTATCGACCTCAGCAGCCTGT
TGCTCCTCCTACTTCAAACGCTTACCCTAACACCCCTTACATATCTTCTGCTTCTTCCTATACTGGGCAGTCTCAGCTGTACGCAGCACA
GCACCAGGCCTCTTCACCTACCTCCAGCCCTGCTACTTCTTTCCCTCCTCCCCCTTCCTCTGGAGCATCCTTCCAGCATGGCGGACCAGG
AGCTCCACCATCATCTTCAGCTTATGCACTGCCTCCTGGAACAACAGGTACACTGCCTGCTGCCAGTGAGCTGCCTGCGTCCCAAAGAAC
AGTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGAC
CATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCAC
CCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGT
GGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCA
GAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTT
CCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTG
TCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAA
GATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCC
CCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATA
TATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCC
TGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCAC
CCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGA
CCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCAC
CTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAA
TATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTA
CGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGG
AAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAA
GGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTAC
TGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCA
CTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTG
TGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGA
AAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTT
ATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTT

>80098_80098_7_SEC31A-ALK_SEC31A_chr4_83763292_ENST00000505472_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1583AA_BP=1020
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM
ADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQ
SQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLIT
AVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLP
KGRPGPVAGHHQMPRVQTQQYYPHVRIAPTVTTWSNKTPTALPSHPPAASPSDTQGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVP
PYPQPQPYQPAQPYPFGTGGSAMYRPQQPVAPPTSNAYPNTPYISSASSYTGQSQLYAAQHQASSPTSSPATSFPPPPSSGASFQHGGPG
APPSSSAYALPPGTTGTLPAASELPASQRTVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNIT
LIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSF
LRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMP
PEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCT
QDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVN
MAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMK

--------------------------------------------------------------
>80098_80098_8_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000264405_ALK_chr2_29446394_ENST00000389048_length(transcript)=4544nt_BP=2403nt
ATGCCAGGTATCGTGCTGCTGTTACAAAGAACTTGATTTGTTTATTTTCTGAACATGTCGGTGATGTTTTCGTGACCAGAAATACACCAT
AGGACACAGGAACTTTTTTTTTTAGATGGAGTTTTGCTCTGTCACTTAGGCTGGAGTGCAGTGGCAAGATCTTGGCTCACTGCAACCTCT
GCCTCCCAGGTTCAAACGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCAAGCCACCATGCCAGGAAATTTTTATAGT
TTTATAAAAATTTTATAGCTGGGATTACATGCATGCGCCACCACGCCCAGCTAATTTTCATAGTTTTAGTAGAGATGGGGTTTTACCATG
TTGGCCAGGCTGGTCTCAAACTTCTGACCTCAAGTGATCTGCCCACCTTTGCCTCCCAAAGTGCTGGGAATACAGGCATGGGCCACCGTA
GGAACTTAATGTTTATGTCAGTTATCAGTTAGTCTATGGTAAAATTGGTTTTGTTATCCATTGTTTTGCTTAAAGTCACAGTTCCTAAAT
TAAGTAACGACTTACTGCAGTTAGATTTCATGCCCATCCATAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTAC
TGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCT
TCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTA
GCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTC
CGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTT
CTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATG
TGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATT
ATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTG
GAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCT
CATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTG
TTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAA
AATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATC
TTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGC
TTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGA
CTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAG
CCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAG
CCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAG
GACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAG
TTCAAACTCAACAATATTATCCCCATGTTAGAATTGCCCCTACTGTCACTACCTGGAGTAACAAAACTCCTACTGCCCTTCCCAGCCATC
CACCTGCAGCCTCTCCCTCTGACACACAGGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTG
GTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGC
AAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACT
GCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCT
TTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCT
CTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCC
TGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCC
AGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCC
ACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACA
TCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCA
CTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGG
AAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGC
AACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTT
TGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCT
CTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCA
CAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTT
CGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCA
AAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAA
CTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACT
TCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATA
CCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGT
GGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAA
AAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGAT
AAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGC
TTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTG

>80098_80098_8_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000264405_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1202AA_BP=640
MVKLVLLSIVLLKVTVPKLSNDLLQLDFMPIHRGILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAV
LSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFE
NVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKE
DLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITR
LITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSL
QDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQ
QLPKGRPGPVAGHHQMPRVQTQQYYPHVRIAPTVTTWSNKTPTALPSHPPAASPSDTQGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHT
QVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGM
PNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLH
VARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVL
LWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEE
EKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNK
PTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQ

--------------------------------------------------------------
>80098_80098_9_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000311785_ALK_chr2_29446394_ENST00000389048_length(transcript)=4931nt_BP=2790nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAG
TAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAA
CATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTT
CTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATG
GAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGA
GAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTG
CAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCAT
CAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATT
GTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATC
TTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGT
TACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGT
GCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAG
GTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTC
CTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTG
CTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACC
ATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCA
ATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTC
GTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATG
TGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAG
AGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGG
CTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTG
GACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGA
ACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTT
CAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAG
GGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCA
TCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATT
TGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGAC
TTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGAC
CAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGC
ATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGC
TGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCA
TCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCC
TCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGG
CTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGA
ACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCC
TCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTC
AGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGA
TTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCC
CAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATA
TGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTG
TATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCC
AGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACC
CTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCT
CCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATA
TGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACG
GCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAA
GCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGG
AGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTG
CCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACT
TCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTG
CCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAA
GAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTAT
GCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGC

>80098_80098_9_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000311785_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1446AA_BP=884
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQ
SPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDF
LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARN
CLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS
GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREE
ERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAK
KEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNS

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>80098_80098_10_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000326950_ALK_chr2_29446394_ENST00000389048_length(transcript)=4811nt_BP=2670nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGGATGAAGTTAAAGGAAGTAG
ATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACAT
TTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTC
ACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAA
ATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAG
CCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAA
CCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAG
CCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTT
CTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTC
GATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTAC
TGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCT
TCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTA
GCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTC
CGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTT
CTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATG
TGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATT
ATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTG
GAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCT
CATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTG
TTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAA
AATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATC
TTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGC
TTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGA
CTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAG
CCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAG
CCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAG
GACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAG
TTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTC
AGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAG
CCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCT
TTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTG
GGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTG
AACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGC
AATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGC
CCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACC
GAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCT
ACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTT
CTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAG
TTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAAC
ATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGC
CGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTC
AACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAG
CTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGG
AGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAA
AGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTG
GGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCC
CTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCA
TTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGA
GGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAG
CTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAA
TACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTC
AATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGG

>80098_80098_10_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000326950_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1406AA_BP=844
MPKVLARMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKG
DVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISC
IAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGI
LAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF
GNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSD
QLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDGL
ITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKP
DEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQ
YANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPG
FIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRK
NITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDL
KSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVK
WMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIE
YCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGG
HVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTA

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>80098_80098_11_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000348405_ALK_chr2_29446394_ENST00000389048_length(transcript)=4703nt_BP=2562nt
GACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGG
CATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCC
TTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGA
TTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATC
CTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTT
TCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAG
CCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGG
CCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATC
CTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCAC
TTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATG
CTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTC
CCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGAC
AGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGC
AGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCA
AACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTG
TAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTG
ATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTC
TAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTA
ATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATG
ATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCC
AAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGG
CTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATA
GCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAA
GCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTG
TAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTG
ACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAA
TTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATT
ATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAG
GTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGC
AGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCT
CCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCC
AGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATT
TCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCA
TCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGC
TGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAA
ACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATA
GAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGT
CCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCA
GTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGC
CCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCAC
TTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGG
AGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTC
GAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACG
GATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAA
AGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCT
CACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATT
ACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATA
GCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGC
TCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCT
TTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGG
TTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGC
TGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATA

>80098_80098_11_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000348405_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1407AA_BP=845
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDG
LITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAK
PDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMS
QYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPP
GFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPR
KNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGD
LKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPV
KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI
EYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEG
GHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLT

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>80098_80098_12_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000395310_ALK_chr2_29446394_ENST00000389048_length(transcript)=4950nt_BP=2809nt
CGGGGAAAGATGTCGCTCCCGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCT
GGCCGGGGAGGAGGGGCGGCGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGC
AGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCT
GCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCT
TGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTG
ATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGAC
AAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATA
TGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAA
GTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGAC
CATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCA
GTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGC
ATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTT
CCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGT
GTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTT
GGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGG
ATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAG
CAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTG
CAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTA
AACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAAC
AAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTC
TTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATT
GATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATT
ATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATC
ACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTAT
GCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGT
CTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGAT
CTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAG
ATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATC
ATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTC
CCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCA
CCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCA
CCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGC
AAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTG
CCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGAC
CCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATC
AGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGG
GGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGG
GACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGC
CCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTG
CCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAA
ATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCC
AAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAG
AGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTG
CCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCA
CCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTG
GAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGC
TTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGT
AACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCG
CTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTG
CCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGA
GCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAA
TGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGT
TCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGT
TTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGG
GTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATAAAGGAGTTATTTGTAATGACTAA

>80098_80098_12_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000395310_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1446AA_BP=884
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQ
SPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDF
LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARN
CLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS
GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREE
ERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAK
KEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNS

--------------------------------------------------------------
>80098_80098_13_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000432794_ALK_chr2_29446394_ENST00000389048_length(transcript)=4931nt_BP=2790nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAG
TAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAA
CATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTT
CTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATG
GAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGA
GAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTG
CAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCAT
CAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATT
GTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATC
TTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGT
TACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGT
GCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAG
GTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTC
CTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTG
CTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACC
ATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCA
ATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTC
GTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATG
TGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAG
AGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGG
CTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTG
GACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGA
ACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTT
CAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAG
GGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCA
TCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATT
TGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGAC
TTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGAC
CAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGC
ATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGC
TGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCA
TCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCC
TCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGG
CTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGA
ACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCC
TCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTC
AGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGA
TTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCC
CAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATA
TGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTG
TATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCC
AGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACC
CTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCT
CCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATA
TGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACG
GCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAA
GCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGG
AGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTG
CCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACT
TCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTG
CCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAA
GAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTAT
GCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGC

>80098_80098_13_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000432794_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1446AA_BP=884
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQ
SPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDF
LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARN
CLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS
GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREE
ERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAK
KEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNS

--------------------------------------------------------------
>80098_80098_14_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000443462_ALK_chr2_29446394_ENST00000389048_length(transcript)=4779nt_BP=2638nt
CTGGCCGGGGAGGAGGGGCGGCGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCA
GGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGAT
ATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCT
GGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCC
CAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAA
ATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGG
AACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAA
GTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGAC
CGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATT
GCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTA
TATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGG
CGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTT
GATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCG
CCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAG
GGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAG
CAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTT
TTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTG
GCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAA
GAGCAGCTCTTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGT
GGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCC
GATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACC
AGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTA
TTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACT
CAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCA
CTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTG
GCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAG
CCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAA
CAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAA
AATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACC
CAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTAC
AAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTG
AAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATG
CCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCC
CTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTC
ATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCAC
GTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACC
TGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGT
GCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTG
CTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATG
GACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATC
ATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAA
GAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCA
GCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGG
CCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAG
CCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACAC
GACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAG
CCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAA
CAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCT
GGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCA
GAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTG
AGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTT
TATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTC
ATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATAAAGGAGTTATTTGT

>80098_80098_14_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000443462_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1442AA_BP=880
LAGEEGRRRMLGESDERCTNAGSGCRRSSPGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVS
GVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAW
NRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAI
AWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNL
DPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQ
QAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAE
EQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKIT
RLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLS
LQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEK
QQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEY
KLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEA
LIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLT
CPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRM
DPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSP
AAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPH
DRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQP

--------------------------------------------------------------
>80098_80098_15_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000448323_ALK_chr2_29446394_ENST00000389048_length(transcript)=4928nt_BP=2787nt
CGGAAGTGTTGGGCGCAGGGCGTGGCTGCGGCTGCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGG
CGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGGATGAAGTTAAAGGAAGTAG
ATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACAT
TTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTC
ACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAA
ATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAG
CCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAA
CCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAG
CCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTT
CTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTC
GATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTAC
TGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCT
TCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTA
GCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTC
CGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTT
CTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATG
TGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATT
ATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTG
GAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGG
CTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGG
AAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTT
TGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGAC
AAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACT
GGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAG
CCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGA
ATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCC
TGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGT
TGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTT
GTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAG
TTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATG
GAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGT
ACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCA
TGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCA
TTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTG
TGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACA
TTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCC
GAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGT
ATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTG
GAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAG
AGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGC
CATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTAT
ACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGG
ACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTG
AGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCT
CTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGG
CATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCT
CCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCT
GTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGG
TACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCC
CTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCT
CTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCA
ACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAA
GAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCT
TCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTT

>80098_80098_15_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000448323_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1445AA_BP=883
MPKVLARMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKG
DVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISC
IAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGI
LAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF
GNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSD
QLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESP
AAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQS
KITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSH
PLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIP
YEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQS
PEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFL
MEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNC
LLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSG
GRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEE
RSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKK
EPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSM

--------------------------------------------------------------
>80098_80098_16_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000500777_ALK_chr2_29446394_ENST00000389048_length(transcript)=4654nt_BP=2513nt
CAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATC
TGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATC
TTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCT
GATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGA
CAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACAT
ATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACA
AGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGA
CCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACC
AGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAG
CATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACT
TCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAG
TGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTT
TGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTG
GATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGA
GCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGT
GCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGT
AAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAA
AGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCT
GACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGA
ACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAA
AGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCT
TTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGT
AGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCG
AAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGC
AGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAG
AGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGC
TGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAA
TGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCG
CCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGAC
CGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCG
GGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAA
GACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGT
TCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGA
GACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTT
GGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGA
CTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGC
CTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATA
CCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCG
GATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCC
GGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGG
GGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGG
CAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATT
CTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTG
GTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTAC
TGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACC
TCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGG
AGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTC
CTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCT
ATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAA
ATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTT
TCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTG

>80098_80098_16_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000500777_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1399AA_BP=837
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM
ADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQ
SQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLT
GNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALC
DLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAA
QGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNV
NPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRG
LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRET
RPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAF
MEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPD
VINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFS
QSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPL

--------------------------------------------------------------
>80098_80098_17_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000505472_ALK_chr2_29446394_ENST00000389048_length(transcript)=4861nt_BP=2720nt
GATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGC
TCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTG
TGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGAT
TGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAA
GCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATG
GGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGT
TCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCA
TAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGT
GATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCAT
GGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCC
CACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGT
TTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGG
CACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGAT
TCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCA
GCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCA
GTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAA
CTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAA
AGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTT
GGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGA
TGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTAT
ATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCAC
TGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGC
AAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCT
CTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCT
GATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGAT
GAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCAT
GCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCC
CAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCATGTTAGAATTGCCCCTAC
TGTCACTACCTGGAGTAACAAAACTCCTACTGCCCTTCCCAGCCATCCACCTGCAGCCTCTCCCTCTGACACACAGGGAGAAAATCCTCC
ACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACC
ACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAG
CAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGT
GCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGA
CCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCAT
CAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGG
GGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCG
GGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGG
CCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCT
GCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGA
AATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACC
CAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGA
GAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGT
GCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCC
ACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGT
GGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAG
CTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGG
TAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTC
GCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTT
GCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTG
AGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAA
ATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGG
TTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATG
TTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGG
GGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGAAATAAAGGAGTTATTTGTAATGACTA

>80098_80098_17_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000505472_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1469AA_BP=907
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM
ADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQ
SQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLIT
AVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLP
KGRPGPVAGHHQMPRVQTQQYYPHVRIAPTVTTWSNKTPTALPSHPPAASPSDTQGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVP
PYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPND
PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVAR
DIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWE
IFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKV
PVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTS
LWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGL

--------------------------------------------------------------
>80098_80098_18_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000505984_ALK_chr2_29446394_ENST00000389048_length(transcript)=4715nt_BP=2574nt
CTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAGTAGATCGTA
CAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTA
CGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGT
ACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTA
TTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGG
ATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAA
TGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTC
CCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGT
TGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTG
CTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCT
GTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATA
TTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAG
ATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTAC
AAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTT
CATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCA
TTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCC
AAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAAT
ACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTG
GAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACC
TTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACT
TCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAA
ATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAA
ATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAG
CTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGG
ACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGG
CTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATG
AATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAA
CTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTC
CCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGC
AGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTG
GCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGG
TGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGG
ACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCC
TGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCT
CCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACA
TTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGG
CGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAA
CAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGG
AGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGC
CTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAG
AATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGG
CAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAG
AGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGC
ACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATA
ATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGAC
TTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTG
GGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGA
AAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAG
AGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTAT
TTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAG
GCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTA
GTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAG

>80098_80098_18_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000505984_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1407AA_BP=845
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDG
LITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAK
PDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMS
QYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPP
GFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPR
KNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGD
LKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPV
KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI
EYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEG
GHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLT

--------------------------------------------------------------
>80098_80098_19_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000508502_ALK_chr2_29446394_ENST00000389048_length(transcript)=4887nt_BP=2746nt
GTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGGCGGCGAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGG
ATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCAC
CCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTC
TCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGAT
TCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGAC
AAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCT
GGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGAT
ATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAA
AATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTC
CTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCC
AGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCA
AACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCA
GCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCA
TCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTG
CTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTC
AGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGC
CGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAG
AAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTA
GGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAG
GAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACA
TTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTA
CATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAA
TCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGA
GAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGA
GATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGAT
GGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGT
ACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTT
CCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCT
AAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAA
TATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTCCCACATCT
CCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAG
CTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACC
TCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAA
GGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTG
GATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGG
TTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCC
ATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCC
AGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTAC
TATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACA
TGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTC
ACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGAC
AGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGT
CCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGG
GAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCT
GTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTC
CACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATA
GCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGG
GCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTC
AATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAG
AATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAA
TGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAA
TGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGAT
GTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAAT
TAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAGGGAACGGA

>80098_80098_19_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000508502_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1446AA_BP=884
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEES
PAAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQ
SKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGS
HPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKI
PYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQ
SPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDF
LMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARN
CLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTS
GGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREE
ERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAK
KEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNS

--------------------------------------------------------------
>80098_80098_20_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000509142_ALK_chr2_29446394_ENST00000389048_length(transcript)=4895nt_BP=2754nt
GCGGCTGCCACGTTGGAACGGAACGTGGAGGTGGCCCTGGCCGGGGAGGAGGGGCGGCGGCGAATGCTGGGAGAGTCCGACGAGCGCTGC
ACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCC
AGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAAT
TAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATA
AAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAG
CTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGG
TAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGC
CAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATC
TTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTC
AGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAA
ACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCT
CCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTG
TCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACA
AGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATA
GTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTG
AGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGT
TCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTG
AATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAG
AAGATCTAGGAAAGAAGATTGCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTG
ATGGGGAGGAGAGCCCTGCTGCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTG
GAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACC
TTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACT
TCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAA
ATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAA
ATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAG
CTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGG
ACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGG
CTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATG
AATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAA
CTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCAGCTTC
CCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGC
AGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTTTGCTG
GCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGG
TGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGG
ACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCC
TGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCT
CCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCGAGACA
TTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTACAGGG
CGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAA
CAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGG
AGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACATCAGC
CTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCCGATAG
AATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGG
CAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAG
AGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGC
ACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATA
ATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGGGAGAC
TTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTG
GGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCATTCTGA
AAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAG
AGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGCTGTAT
TTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAATACAAG
GCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTA
GTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGGGAGAG

>80098_80098_20_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000509142_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1445AA_BP=883
MPKVLARMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKG
DVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISC
IAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGI
LAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSF
GNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSD
QLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESP
AAEEQLLGEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQS
KITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSH
PLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIP
YEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPPGFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQS
PEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFL
MEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNC
LLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSG
GRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEE
RSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKK
EPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSM

--------------------------------------------------------------
>80098_80098_21_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000513858_ALK_chr2_29446394_ENST00000389048_length(transcript)=4720nt_BP=2579nt
GAATGCTGGGAGAGTCCGACGAGCGCTGCACTAACGCAGGATCCGGCTGCCGAAGGTCCTCGCCAGCAGGATGAAGTTAAAGGAAGTAGA
TCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTAGCAACAGGAACATCTGCTCAGCAATTGGATGCAACATT
TAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCCTTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCA
CAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGATGTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAA
TATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTGATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGC
CTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAATCTGAAATCTACATATGGGATCTAAATAATTTTGCAAC
CCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATTGCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGC
CAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATCATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTC
TGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAGGATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCG
ATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTGGCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACT
GAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAGGTGTTATATGAACTTCCCACCAACACACAGTGGTGCTT
CGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTTGATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAG
CACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGGAATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCC
GTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAGAAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTC
TTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCTCATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGT
GTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAACTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTA
TTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGGTCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGG
AAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTC
ATCTGGAGGAACATTTAATATCTCTGTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGT
TGACCTTTGTTTACATGATAACCGCATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAA
ATACTTCGCAAAATCCCAAAGCAAAATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCT
TAAAAATTGGAGAGAGGCTTTAGCTGCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCT
TGAAAATGAAGGAGATAGCCTCCTGCAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGAC
TAAAGCTCAAGATGGAAGCCACCCTTTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGC
CATGGACACTAGTACTGTAGGAGTTCTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGC
CTTGGCTTTTCTTCCTGACAACACCAACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGG
ACATGAATCACCTAAAATTCCGTACGAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGT
TCAAACTCAACAATATTATCCCCATGGAGAAAATCCTCCACCTCCGGGTTTCATAATGCATGGAAATGTTAATCCAAATGCTGCTGGTCA
GCTTCCCACATCTCCAGGTCATATGCACACCCAGGTACCACCTTATCCACAGCCACAGCTGTACCGCCGGAAGCACCAGGAGCTGCAAGC
CATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCATCATGACCGACTACAACCCCAACTACTGCTT
TGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCCTCATTCGGGGTCTGGGCCATGGCGCCTTTGG
GGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGGCTGTGAAGACGCTGCCTGAAGTGTGCTCTGA
ACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGAACATTGTTCGCTGCATTGGGGTGAGCCTGCA
ATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCCTCCGAGAGACCCGCCCTCGCCCGAGCCAGCC
CTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTCAGTATTTGGAGGAAAACCACTTCATCCACCG
AGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGATTGGAGACTTCGGGATGGCCCGAGACATCTA
CAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCCCAGAGGCCTTCATGGAAGGAATATTCACTTC
TAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATATGCCATACCCCAGCAAAAGCAACCAGGAAGT
TCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTGTATACCGGATAATGACTCAGTGCTGGCAACA
TCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCCAGGACCCGGATGTAATCAACACCGCTTTGCC
GATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACCCTGAGGGGGTTCCTCCTCTCCTGGTCTCTCA
ACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCTCCTCTGGCAAGGCTGCAAAGAAACCCACAGC
TGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATATGGCATTCTCTCAGTCCAACCCTCCTTCGGA
GTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACGGCTCCTGGTTTACAGAGAAACCCACCAAAAA
GAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAAGCTGTACTGTCCCACCTAACGTTGCAACTGG
GAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGGAGGTACCTCTGTTCAGGCTACGTCACTTCCC
TTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTGCCCCTGGAGCTGGTCATTACGAGGATACCAT
TCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACTTCTCTTCCTTGGGATCCCTAAGACCGTGGAG
GAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTGCCAACCTATTTTGAAGTACCACCAAAAAAGC
TGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAAGAAGAAAATATCATAAAAATGAGTGATAAAT
ACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTATGCTTCTTTCAAATTGTGTGTGCTCTGCTTCA
ATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGCCTTGTTGATGTGGACATGAGCCATTTGAGGG

>80098_80098_21_SEC31A-ALK_SEC31A_chr4_83765539_ENST00000513858_ALK_chr2_29446394_ENST00000389048_length(amino acids)=1407AA_BP=845
MPKVLASRMKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSK
GDVSGVLIAGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDIS
CIAWNRQVQHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARG
ILAIAWSMADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSS
FGNLDPFGTGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRS
DQLQQAVQSQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKHIKEEKEESEFLPSSGGTFNISVSGDIDG
LITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLITAVVMKNWKEIVESCDLKNWREALAAVLTYAK
PDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDLIEKVVILRKAVQLTQAMDTSTVGVLLAAKMS
QYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLPKGRPGPVAGHHQMPRVQTQQYYPHGENPPPP
GFIMHGNVNPNAAGQLPTSPGHMHTQVPPYPQPQLYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPR
KNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGD
LKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPV
KWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERI
EYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAAPPPLPTTSSGKAAKKPTAAEISVRVPRGPAVEG
GHVNMAFSQSNPPSELHKVHGSRNKPTSLWNPTYGSWFTEKPTKKNNPIAKKEPHDRGNLGLEGSCTVPPNVATGRLPGASLLLEPSSLT

--------------------------------------------------------------
>80098_80098_22_SEC31A-ALK_SEC31A_chr4_83769956_ENST00000355196_ALK_chr2_29446394_ENST00000389048_length(transcript)=5021nt_BP=2880nt
GCGGAATAGTGGGTTTTGCTGCAACCGGTTTATTTTCCTTCTGTTTTCACCCATTCTGGCACAATCTGGCGCCATCGTCCTTCTTGTGAG
GCCAAGCCTGAAAATGCGAAGCAGAGAGGCAGGACCAAAATTGAGGCGAATCCAGGAACCTGCCAATGGGTCTCCGGGTGCGGTCTCTGA
AACTGGAGGATATCGGGAGGAAAGGCTCTCCGATGCGGAGATAATGGGGAAGCTCTTGGCATGGTTGGCTGTAGGTATGTGATACCGGAG
GAGCAGGAGTCAAATAGGATACGCCGACTTTTAATTCAAGGAACCCTTTTCTGAAACACTTTGCCACAATGAAGGAAATAAGATTACAGC
CGAAGATACATATTAAGGATGAAGTTAAAGGAAGTAGATCGTACAGCCATGCAGGCATGGAGCCCTGCCCAGAATCACCCCATTTACCTA
GCAACAGGAACATCTGCTCAGCAATTGGATGCAACATTTAGTACGAATGCTTCCCTTGAGATATTTGAATTAGACCTCTCTGATCCATCC
TTGGATATGAAATCTTGTGCCACATTCTCCTCTTCTCACAGGTACCACAAGTTGATTTGGGGGCCTTATAAAATGGATTCCAAAGGAGAT
GTCTCTGGAGTTCTGATTGCAGGTGGTGAAAATGGAAATATTATTCTCTATGATCCTTCTAAAATTATAGCTGGAGACAAGGAAGTTGTG
ATTGCCCAGAATGACAAGCATACTGGCCCAGTGAGAGCCTTGGATGTGAACATTTTCCAGACTAATCTGGTAGCTTCTGGTGCTAATGAA
TCTGAAATCTACATATGGGATCTAAATAATTTTGCAACCCCAATGACACCAGGAGCCAAAACACAGCCGCCAGAAGATATCAGCTGCATT
GCATGGAACAGACAAGTTCAGCATATTTTAGCATCAGCCAGTCCCAGTGGCCGGGCCACTGTATGGGATCTTAGAAAAAATGAGCCAATC
ATCAAAGTCAGTGACCATAGTAACAGAATGCATTGTTCTGGGTTGGCATGGCATCCTGATGTTGCTACTCAGATGGTCCTTGCCTCCGAG
GATGACCGGTTACCAGTGATCCAGATGTGGGATCTTCGATTTGCTTCCTCTCCACTTCGTGTCCTGGAAAACCATGCCAGGGGGATTTTG
GCAATTGCTTGGAGCATGGCAGATCCTGAATTGTTACTGAGCTGTGGAAAAGATGCTAAGATTCTCTGCTCCAATCCAAACACAGGAGAG
GTGTTATATGAACTTCCCACCAACACACAGTGGTGCTTCGATATTCAGTGGTGTCCCCGAAATCCTGCTGTCTTATCAGCTGCTTCGTTT
GATGGGCGTATCAGTGTTTATTCTATCATGGGAGGTAGCACAGATGGTTTAAGACAGAAACAAGTTGACAAGCTTTCATCATCTTTTGGG
AATCTTGATCCCTTTGGCACAGGACAGCCCCTTCCTCCGTTACAAATTCCACAGCAGACTGCTCAGCATAGTATAGTGCTGCCTCTGAAG
AAGCCGCCCAAGTGGATTCGAAGGCCTGTTGGTGCTTCTTTTTCATTTGGAGGCAAACTGGTTACGTTTGAGAATGTCAGAATGCCTTCT
CATCAGGGAGCTGAGCAGCAGCAGCAGCAGCACCATGTGTTCATTAGTCAGGTTGTAACAGAAAAGGAGTTCCTCAGCCGATCAGACCAA
CTTCAGCAGGCTGTGCAGTCACAAGGATTTATCAATTATTGCCAAAAAAAAATTGATGCTTCTCAGACTGAATTTGAGAAAAATGTGTGG
TCCTTTTTGAAGGTAAACTTTGAGGATGATTCTCGTGGAAAATACCTTGAACTTCTAGGATACAGAAAAGAAGATCTAGGAAAGAAGATT
GCTTTGGCCTTGAACAAAGTGGATGGAGCCAATGTGGCTCTTAAAGACTCTGACCAAGTAGCACAGAGTGATGGGGAGGAGAGCCCTGCT
GCTGAAGAGCAGCTCTTGGGAGAGCACATTAAAGAGGAAAAAGAAGAATCTGAATTTCTACCCTCATCTGGAGGAACATTTAATATCTCT
GTCAGTGGGGACATTGATGGTTTAATTACTCAGGCTTTGCTGACGGGCAATTTTGAGAGTGCTGTTGACCTTTGTTTACATGATAACCGC
ATGGCCGATGCCATTATATTGGCCATAGCAGGTGGACAAGAACTCTTGGCTCGAACCCAGAAAAAATACTTCGCAAAATCCCAAAGCAAA
ATTACCAGGCTCATCACTGCAGTGGTGATGAAGAACTGGAAAGAGATTGTTGAGTCTTGTGATCTTAAAAATTGGAGAGAGGCTTTAGCT
GCAGTATTGACTTATGCAAAGCCGGATGAATTTTCAGCCCTTTGTGATCTTTTGGGAACCAGGCTTGAAAATGAAGGAGATAGCCTCCTG
CAGACTCAAGCATGTCTCTGCTATATTTGTGCAGGGAATGTAGAGAAATTAGTTGCATGTTGGACTAAAGCTCAAGATGGAAGCCACCCT
TTGTCACTTCAGGATCTGATTGAGAAAGTTGTCATCCTGCGAAAAGCTGTGCAACTCACTCAAGCCATGGACACTAGTACTGTAGGAGTT
CTCTTGGCTGCGAAGATGAGTCAGTATGCCAATTTGTTGGCAGCTCAGGGCAGTATTGCTGCAGCCTTGGCTTTTCTTCCTGACAACACC
AACCAGCCAAATATCATGCAGCTTCGTGACAGACTTTGTAGAGCACAAGGAGAGCCTGTAGCAGGACATGAATCACCTAAAATTCCGTAC
GAGAAACAGCAGCTCCCCAAGGGCAGGCCTGGACCAGTTGCTGGCCACCACCAGATGCCAAGAGTTCAAACTCAACAATATTATCCCCAT
TGTACCGCCGGAAGCACCAGGAGCTGCAAGCCATGCAGATGGAGCTGCAGAGCCCTGAGTACAAGCTGAGCAAGCTCCGCACCTCGACCA
TCATGACCGACTACAACCCCAACTACTGCTTTGCTGGCAAGACCTCCTCCATCAGTGACCTGAAGGAGGTGCCGCGGAAAAACATCACCC
TCATTCGGGGTCTGGGCCATGGCGCCTTTGGGGAGGTGTATGAAGGCCAGGTGTCCGGAATGCCCAACGACCCAAGCCCCCTGCAAGTGG
CTGTGAAGACGCTGCCTGAAGTGTGCTCTGAACAGGACGAACTGGATTTCCTCATGGAAGCCCTGATCATCAGCAAATTCAACCACCAGA
ACATTGTTCGCTGCATTGGGGTGAGCCTGCAATCCCTGCCCCGGTTCATCCTGCTGGAGCTCATGGCGGGGGGAGACCTCAAGTCCTTCC
TCCGAGAGACCCGCCCTCGCCCGAGCCAGCCCTCCTCCCTGGCCATGCTGGACCTTCTGCACGTGGCTCGGGACATTGCCTGTGGCTGTC
AGTATTTGGAGGAAAACCACTTCATCCACCGAGACATTGCTGCCAGAAACTGCCTCTTGACCTGTCCAGGCCCTGGAAGAGTGGCCAAGA
TTGGAGACTTCGGGATGGCCCGAGACATCTACAGGGCGAGCTACTATAGAAAGGGAGGCTGTGCCATGCTGCCAGTTAAGTGGATGCCCC
CAGAGGCCTTCATGGAAGGAATATTCACTTCTAAAACAGACACATGGTCCTTTGGAGTGCTGCTATGGGAAATCTTTTCTCTTGGATATA
TGCCATACCCCAGCAAAAGCAACCAGGAAGTTCTGGAGTTTGTCACCAGTGGAGGCCGGATGGACCCACCCAAGAACTGCCCTGGGCCTG
TATACCGGATAATGACTCAGTGCTGGCAACATCAGCCTGAAGACAGGCCCAACTTTGCCATCATTTTGGAGAGGATTGAATACTGCACCC
AGGACCCGGATGTAATCAACACCGCTTTGCCGATAGAATATGGTCCACTTGTGGAAGAGGAAGAGAAAGTGCCTGTGAGGCCCAAGGACC
CTGAGGGGGTTCCTCCTCTCCTGGTCTCTCAACAGGCAAAACGGGAGGAGGAGCGCAGCCCAGCTGCCCCACCACCTCTGCCTACCACCT
CCTCTGGCAAGGCTGCAAAGAAACCCACAGCTGCAGAGATCTCTGTTCGAGTCCCTAGAGGGCCGGCCGTGGAAGGGGGACACGTGAATA
TGGCATTCTCTCAGTCCAACCCTCCTTCGGAGTTGCACAAGGTCCACGGATCCAGAAACAAGCCCACCAGCTTGTGGAACCCAACGTACG
GCTCCTGGTTTACAGAGAAACCCACCAAAAAGAATAATCCTATAGCAAAGAAGGAGCCACACGACAGGGGTAACCTGGGGCTGGAGGGAA
GCTGTACTGTCCCACCTAACGTTGCAACTGGGAGACTTCCGGGGGCCTCACTGCTCCTAGAGCCCTCTTCGCTGACTGCCAATATGAAGG
AGGTACCTCTGTTCAGGCTACGTCACTTCCCTTGTGGGAATGTCAATTACGGCTACCAGCAACAGGGCTTGCCCTTAGAAGCCGCTACTG
CCCCTGGAGCTGGTCATTACGAGGATACCATTCTGAAAAGCAAGAATAGCATGAACCAGCCTGGGCCCTGAGCTCGGTCGCACACTCACT
TCTCTTCCTTGGGATCCCTAAGACCGTGGAGGAGAGAGAGGCAATGGCTCCTTCACAAACCAGAGACCAAATGTCACGTTTTGTTTTGTG
CCAACCTATTTTGAAGTACCACCAAAAAAGCTGTATTTTGAAAATGCTTTAGAAAGGTTTTGAGCATGGGTTCATCCTATTCTTTCGAAA
GAAGAAAATATCATAAAAATGAGTGATAAATACAAGGCCCAGATGTGGTTGCATAAGGTTTTTATGCATGTTTGTTGTATACTTCCTTAT
GCTTCTTTCAAATTGTGTGTGCTCTGCTTCAATGTAGTCAGAATTAGCTGCTTCTATGTTTCATAGTTGGGGTCATAGATGTTTCCTTGC

>80098_80098_22_SEC31A-ALK_SEC31A_chr4_83769956_ENST00000355196_ALK_chr2_29446394_ENST00000389048_length(amino acids)=856AA_BP=834
MKLKEVDRTAMQAWSPAQNHPIYLATGTSAQQLDATFSTNASLEIFELDLSDPSLDMKSCATFSSSHRYHKLIWGPYKMDSKGDVSGVLI
AGGENGNIILYDPSKIIAGDKEVVIAQNDKHTGPVRALDVNIFQTNLVASGANESEIYIWDLNNFATPMTPGAKTQPPEDISCIAWNRQV
QHILASASPSGRATVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDVATQMVLASEDDRLPVIQMWDLRFASSPLRVLENHARGILAIAWSM
ADPELLLSCGKDAKILCSNPNTGEVLYELPTNTQWCFDIQWCPRNPAVLSAASFDGRISVYSIMGGSTDGLRQKQVDKLSSSFGNLDPFG
TGQPLPPLQIPQQTAQHSIVLPLKKPPKWIRRPVGASFSFGGKLVTFENVRMPSHQGAEQQQQQHHVFISQVVTEKEFLSRSDQLQQAVQ
SQGFINYCQKKIDASQTEFEKNVWSFLKVNFEDDSRGKYLELLGYRKEDLGKKIALALNKVDGANVALKDSDQVAQSDGEESPAAEEQLL
GEHIKEEKEESEFLPSSGGTFNISVSGDIDGLITQALLTGNFESAVDLCLHDNRMADAIILAIAGGQELLARTQKKYFAKSQSKITRLIT
AVVMKNWKEIVESCDLKNWREALAAVLTYAKPDEFSALCDLLGTRLENEGDSLLQTQACLCYICAGNVEKLVACWTKAQDGSHPLSLQDL
IEKVVILRKAVQLTQAMDTSTVGVLLAAKMSQYANLLAAQGSIAAALAFLPDNTNQPNIMQLRDRLCRAQGEPVAGHESPKIPYEKQQLP

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Fusion Gene PPI Analysis for SEC31A-ALK


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126161_471875.33333333333341107.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925161_471836.33333333333341182.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925161_471836.33333333333341182.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329161_471875.33333333333341221.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127161_471875.33333333333341221.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128161_471875.33333333333341234.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026161_471870.33333333333341201.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127161_471875.33333333333341221.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823161_471836.33333333333341068.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127161_471875.33333333333341206.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126161_471875.33333333333341107.0SEC13
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924161_471836.33333333333341068.0SEC13


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneSEC31Achr4:83765539chr2:29446394ENST00000311785-2126800_1113875.33333333333341107.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000326950-1925800_1113836.33333333333341182.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000348405-1925800_1113836.33333333333341182.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000355196-2329800_1113875.33333333333341221.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000395310-2127800_1113875.33333333333341221.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000432794-2128800_1113875.33333333333341234.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000443462-2026800_1113870.33333333333341201.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000448323-2127800_1113875.33333333333341221.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000500777-1823800_1113836.33333333333341068.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000508502-2127800_1113875.33333333333341206.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000509142-2126800_1113875.33333333333341107.0PDCD6
HgeneSEC31Achr4:83765539chr2:29446394ENST00000513858-1924800_1113836.33333333333341068.0PDCD6


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SEC31A-ALK


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneALKQ9UM73DB08865CrizotinibInhibitorSmall moleculeApproved
TgeneALKQ9UM73DB09063CeritinibAntagonistSmall moleculeApproved
TgeneALKQ9UM73DB11363AlectinibInhibitorSmall moleculeApproved|Investigational
TgeneALKQ9UM73DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
TgeneALKQ9UM73DB12130LorlatinibInhibitorSmall moleculeApproved|Investigational
TgeneALKQ9UM73DB12141GilteritinibInhibitorSmall moleculeApproved|Investigational
TgeneALKQ9UM73DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for SEC31A-ALK


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSEC31AC0079744Diffuse Large B-Cell Lymphoma1CTD_human
TgeneC0007131Non-Small Cell Lung Carcinoma28CGI;CTD_human
TgeneC0027819Neuroblastoma13CGI;CTD_human;ORPHANET
TgeneC0152013Adenocarcinoma of lung (disorder)8CGI;CTD_human
TgeneC2751681NEUROBLASTOMA, SUSCEPTIBILITY TO, 38CLINGEN;UNIPROT
TgeneC0206180Ki-1+ Anaplastic Large Cell Lymphoma6CGI;CTD_human
TgeneC0334121Inflammatory Myofibroblastic Tumor4CGI;CTD_human;ORPHANET
TgeneC0018199Granuloma, Plasma Cell3CTD_human
TgeneC0007621Neoplastic Cell Transformation2CTD_human
TgeneC0027627Neoplasm Metastasis2CTD_human
TgeneC0238463Papillary thyroid carcinoma2ORPHANET
TgeneC0001973Alcoholic Intoxication, Chronic1PSYGENET
TgeneC0006118Brain Neoplasms1CGI;CTD_human
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0007134Renal Cell Carcinoma1CTD_human
TgeneC0011570Mental Depression1PSYGENET
TgeneC0011581Depressive disorder1PSYGENET
TgeneC0027643Neoplasm Recurrence, Local1CTD_human
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0079744Diffuse Large B-Cell Lymphoma1CTD_human
TgeneC0085269Plasma Cell Granuloma, Pulmonary1CTD_human
TgeneC0153633Malignant neoplasm of brain1CGI;CTD_human
TgeneC0278601Inflammatory Breast Carcinoma1CTD_human
TgeneC0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
TgeneC0496899Benign neoplasm of brain, unspecified1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC0750974Brain Tumor, Primary1CTD_human
TgeneC0750977Recurrent Brain Neoplasm1CTD_human
TgeneC0750979Primary malignant neoplasm of brain1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1266042Chromophobe Renal Cell Carcinoma1CTD_human
TgeneC1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
TgeneC1266044Collecting Duct Carcinoma of the Kidney1CTD_human
TgeneC1306837Papillary Renal Cell Carcinoma1CTD_human
TgeneC1332079Anaplastic Large Cell Lymphoma, ALK-Positive1ORPHANET
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC1527390Neoplasms, Intracranial1CTD_human
TgeneC2931189Neural crest tumor1ORPHANET
TgeneC3899155hereditary neuroblastoma1GENOMICS_ENGLAND
TgeneC4704874Mammary Carcinoma, Human1CTD_human