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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EML4-NTRK3 (FusionGDB2 ID:HG27436TG4916)

Fusion Gene Summary for EML4-NTRK3

check button Fusion gene summary
Fusion gene informationFusion gene name: EML4-NTRK3
Fusion gene ID: hg27436tg4916
HgeneTgene
Gene symbol

EML4

NTRK3

Gene ID

27436

4916

Gene nameEMAP like 4neurotrophic receptor tyrosine kinase 3
SynonymsC2orf2|ELP120|EMAP-4|EMAPL4|ROPP120GP145-TrkC|TRKC|gp145(trkC)
Cytomap('EML4')('NTRK3')

2p21

15q25.3

Type of geneprotein-codingprotein-coding
Descriptionechinoderm microtubule-associated protein-like 4echinoderm microtubule associated protein like 4restrictedly overexpressed proliferation-associated proteinropp 120NT-3 growth factor receptorETS related protein-neurotrophic receptor tyrosine kinase fusion proteinETV6-NTRK3 fusionneurotrophic tyrosine kinase, receptor, type 3tyrosine kinase receptor C
Modification date2020031320200313
UniProtAcc

Q9HC35

Q16288

Ensembl transtripts involved in fusion geneENST00000318522, ENST00000401738, 
ENST00000402711, ENST00000453191, 
ENST00000482660, 
Fusion gene scores* DoF score22 X 32 X 18=1267215 X 19 X 11=3135
# samples 4315
** MAII scorelog2(43/12672*10)=-4.88116377049015
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/3135*10)=-4.38543103719352
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EML4 [Title/Abstract] AND NTRK3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEML4(42491871)-NTRK3(88576276), # samples:3
Anticipated loss of major functional domain due to fusion event.EML4-NTRK3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EML4-NTRK3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EML4-NTRK3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EML4-NTRK3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNTRK3

GO:0000187

activation of MAPK activity

23027130

TgeneNTRK3

GO:0001933

negative regulation of protein phosphorylation

23027130

TgeneNTRK3

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

23027130

TgeneNTRK3

GO:0008284

positive regulation of cell proliferation

23027130

TgeneNTRK3

GO:0010628

positive regulation of gene expression

23027130

TgeneNTRK3

GO:0030335

positive regulation of cell migration

23027130

TgeneNTRK3

GO:0032148

activation of protein kinase B activity

23027130

TgeneNTRK3

GO:0033138

positive regulation of peptidyl-serine phosphorylation

23027130

TgeneNTRK3

GO:0050927

positive regulation of positive chemotaxis

23027130

TgeneNTRK3

GO:0090630

activation of GTPase activity

23027130

TgeneNTRK3

GO:2000251

positive regulation of actin cytoskeleton reorganization

23027130


check buttonFusion gene breakpoints across EML4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across NTRK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-FB-AAPP-01AEML4chr2

42491871

-NTRK3chr15

88576276

-
ChimerDB4PAADTCGA-FB-AAPP-01AEML4chr2

42491871

+NTRK3chr15

88576276

-
ChimerDB4PAADTCGA-FB-AAPPEML4chr2

42491871

+NTRK3chr15

88576276

-
ChimerKB4..EML4chr2

42472644

+NTRK3chr15

42472644

-


Top

Fusion Gene ORF analysis for EML4-NTRK3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000318522ENST00000540489EML4chr2

42491871

+NTRK3chr15

88576276

-
5CDS-5UTRENST00000318522ENST00000558306EML4chr2

42491871

+NTRK3chr15

88576276

-
5CDS-5UTRENST00000401738ENST00000540489EML4chr2

42491871

+NTRK3chr15

88576276

-
5CDS-5UTRENST00000401738ENST00000558306EML4chr2

42491871

+NTRK3chr15

88576276

-
5CDS-5UTRENST00000402711ENST00000540489EML4chr2

42491871

+NTRK3chr15

88576276

-
5CDS-5UTRENST00000402711ENST00000558306EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000317501EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000355254EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000357724EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000360948EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000394480EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000542733EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000557856EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000318522ENST00000558676EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000317501EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000355254EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000357724EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000360948EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000394480EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000542733EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000557856EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000401738ENST00000558676EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000317501EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000355254EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000357724EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000360948EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000394480EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000542733EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000557856EML4chr2

42491871

+NTRK3chr15

88576276

-
In-frameENST00000402711ENST00000558676EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000317501EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000355254EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000357724EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000360948EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000394480EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000542733EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000557856EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000453191ENST00000558676EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000317501EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000355254EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000357724EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000360948EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000394480EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000542733EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000557856EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-3CDSENST00000482660ENST00000558676EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-5UTRENST00000453191ENST00000540489EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-5UTRENST00000453191ENST00000558306EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-5UTRENST00000482660ENST00000540489EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-5UTRENST00000482660ENST00000558306EML4chr2

42491871

+NTRK3chr15

88576276

-
intron-intronENST00000318522ENST00000317501EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000355254EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000357724EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000360948EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000394480EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000540489EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000542733EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000557856EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000558306EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000318522ENST00000558676EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000317501EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000355254EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000357724EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000360948EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000394480EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000540489EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000542733EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000557856EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000558306EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000401738ENST00000558676EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000317501EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000355254EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000357724EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000360948EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000394480EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000540489EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000542733EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000557856EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000558306EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000402711ENST00000558676EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000317501EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000355254EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000357724EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000360948EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000394480EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000540489EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000542733EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000557856EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000558306EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000453191ENST00000558676EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000317501EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000355254EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000357724EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000360948EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000394480EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000540489EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000542733EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000557856EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000558306EML4chr2

42472644

+NTRK3chr15

42472644

-
intron-intronENST00000482660ENST00000558676EML4chr2

42472644

+NTRK3chr15

42472644

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000318522EML4chr242491871+ENST00000394480NTRK3chr1588576276-39479292622010582
ENST00000318522EML4chr242491871+ENST00000557856NTRK3chr1588576276-21559292622010582
ENST00000318522EML4chr242491871+ENST00000357724NTRK3chr1588576276-21979292622052596
ENST00000318522EML4chr242491871+ENST00000355254NTRK3chr1588576276-21559292622010582
ENST00000318522EML4chr242491871+ENST00000360948NTRK3chr1588576276-21979292622052596
ENST00000318522EML4chr242491871+ENST00000542733NTRK3chr1588576276-19549292621680472
ENST00000318522EML4chr242491871+ENST00000558676NTRK3chr1588576276-18559292621674470
ENST00000318522EML4chr242491871+ENST00000317501NTRK3chr1588576276-33509292621371369
ENST00000402711EML4chr242491871+ENST00000394480NTRK3chr1588576276-37707522591833524
ENST00000402711EML4chr242491871+ENST00000557856NTRK3chr1588576276-19787522591833524
ENST00000402711EML4chr242491871+ENST00000357724NTRK3chr1588576276-20207522591875538
ENST00000402711EML4chr242491871+ENST00000355254NTRK3chr1588576276-19787522591833524
ENST00000402711EML4chr242491871+ENST00000360948NTRK3chr1588576276-20207522591875538
ENST00000402711EML4chr242491871+ENST00000542733NTRK3chr1588576276-17777522591503414
ENST00000402711EML4chr242491871+ENST00000558676NTRK3chr1588576276-16787522591497412
ENST00000402711EML4chr242491871+ENST00000317501NTRK3chr1588576276-31737522591194311
ENST00000401738EML4chr242491871+ENST00000394480NTRK3chr1588576276-38368181511899582
ENST00000401738EML4chr242491871+ENST00000557856NTRK3chr1588576276-20448181511899582
ENST00000401738EML4chr242491871+ENST00000357724NTRK3chr1588576276-20868181511941596
ENST00000401738EML4chr242491871+ENST00000355254NTRK3chr1588576276-20448181511899582
ENST00000401738EML4chr242491871+ENST00000360948NTRK3chr1588576276-20868181511941596
ENST00000401738EML4chr242491871+ENST00000542733NTRK3chr1588576276-18438181511569472
ENST00000401738EML4chr242491871+ENST00000558676NTRK3chr1588576276-17448181511563470
ENST00000401738EML4chr242491871+ENST00000317501NTRK3chr1588576276-32398181511260369

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000318522ENST00000394480EML4chr242491871+NTRK3chr1588576276-0.0018217780.99817824
ENST00000318522ENST00000557856EML4chr242491871+NTRK3chr1588576276-0.0038355030.99616456
ENST00000318522ENST00000357724EML4chr242491871+NTRK3chr1588576276-0.0036841560.9963159
ENST00000318522ENST00000355254EML4chr242491871+NTRK3chr1588576276-0.0038355030.99616456
ENST00000318522ENST00000360948EML4chr242491871+NTRK3chr1588576276-0.0036841560.9963159
ENST00000318522ENST00000542733EML4chr242491871+NTRK3chr1588576276-0.002489910.9975101
ENST00000318522ENST00000558676EML4chr242491871+NTRK3chr1588576276-0.0027837640.9972162
ENST00000318522ENST00000317501EML4chr242491871+NTRK3chr1588576276-0.0007174150.99928266
ENST00000402711ENST00000394480EML4chr242491871+NTRK3chr1588576276-0.0016611060.9983388
ENST00000402711ENST00000557856EML4chr242491871+NTRK3chr1588576276-0.0031651380.99683493
ENST00000402711ENST00000357724EML4chr242491871+NTRK3chr1588576276-0.0027558470.9972441
ENST00000402711ENST00000355254EML4chr242491871+NTRK3chr1588576276-0.0031651380.99683493
ENST00000402711ENST00000360948EML4chr242491871+NTRK3chr1588576276-0.0027558470.9972441
ENST00000402711ENST00000542733EML4chr242491871+NTRK3chr1588576276-0.0022123960.9977876
ENST00000402711ENST00000558676EML4chr242491871+NTRK3chr1588576276-0.0021465710.99785346
ENST00000402711ENST00000317501EML4chr242491871+NTRK3chr1588576276-0.0009627620.99903727
ENST00000401738ENST00000394480EML4chr242491871+NTRK3chr1588576276-0.0017564210.9982436
ENST00000401738ENST00000557856EML4chr242491871+NTRK3chr1588576276-0.0036665090.9963335
ENST00000401738ENST00000357724EML4chr242491871+NTRK3chr1588576276-0.0034902470.99650973
ENST00000401738ENST00000355254EML4chr242491871+NTRK3chr1588576276-0.0036665090.9963335
ENST00000401738ENST00000360948EML4chr242491871+NTRK3chr1588576276-0.0034902470.99650973
ENST00000401738ENST00000542733EML4chr242491871+NTRK3chr1588576276-0.0022086870.9977913
ENST00000401738ENST00000558676EML4chr242491871+NTRK3chr1588576276-0.0025782860.99742174
ENST00000401738ENST00000317501EML4chr242491871+NTRK3chr1588576276-0.0006540370.99934596

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Fusion Genomic Features for EML4-NTRK3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for EML4-NTRK3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:42491871/chr15:88576276)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EML4

Q9HC35

NTRK3

Q16288

FUNCTION: Essential for the formation and stability of microtubules (MTs) (PubMed:16890222, PubMed:31409757). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (PubMed:25789526). Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (PubMed:25789526). {ECO:0000269|PubMed:16890222, ECO:0000269|PubMed:25789526, ECO:0000269|PubMed:31409757}.FUNCTION: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation. {ECO:0000269|PubMed:25196463}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115538_839465613.0DomainProtein kinase
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118538_839465826.0DomainProtein kinase
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119538_839465840.0DomainProtein kinase
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219538_839465826.0DomainProtein kinase
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014538_839465613.0DomainProtein kinase
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115544_552465613.0Nucleotide bindingATP
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118544_552465826.0Nucleotide bindingATP
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119544_552465840.0Nucleotide bindingATP
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219544_552465826.0Nucleotide bindingATP
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014544_552465613.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+6231_249222982.0RegionMicrotubule-binding
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+5221_249164924.0RegionMicrotubule-binding
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623259_297222982.0RepeatNote=WD 1
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623301_348222982.0RepeatNote=WD 2
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623356_396222982.0RepeatNote=WD 3
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623403_438222982.0RepeatNote=WD 4
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623445_484222982.0RepeatNote=WD 5
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623500_538222982.0RepeatNote=WD 6
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623543_579222982.0RepeatNote=WD 7
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623582_621222982.0RepeatNote=WD 8
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623625_662222982.0RepeatNote=WD 9
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623668_704222982.0RepeatNote=WD 10
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623711_750222982.0RepeatNote=WD 11
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623760_818222982.0RepeatNote=WD 12
HgeneEML4chr2:42491871chr15:88576276ENST00000318522+623825_864222982.0RepeatNote=WD 13
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522259_297164924.0RepeatNote=WD 1
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522301_348164924.0RepeatNote=WD 2
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522356_396164924.0RepeatNote=WD 3
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522403_438164924.0RepeatNote=WD 4
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522445_484164924.0RepeatNote=WD 5
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522500_538164924.0RepeatNote=WD 6
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522543_579164924.0RepeatNote=WD 7
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522582_621164924.0RepeatNote=WD 8
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522625_662164924.0RepeatNote=WD 9
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522668_704164924.0RepeatNote=WD 10
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522711_750164924.0RepeatNote=WD 11
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522760_818164924.0RepeatNote=WD 12
HgeneEML4chr2:42491871chr15:88576276ENST00000402711+522825_864164924.0RepeatNote=WD 13
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115160_209465613.0DomainNote=LRRCT
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115210_300465613.0DomainNote=Ig-like C2-type 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115309_382465613.0DomainNote=Ig-like C2-type 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118160_209465826.0DomainNote=LRRCT
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118210_300465826.0DomainNote=Ig-like C2-type 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118309_382465826.0DomainNote=Ig-like C2-type 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119160_209465840.0DomainNote=LRRCT
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119210_300465840.0DomainNote=Ig-like C2-type 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119309_382465840.0DomainNote=Ig-like C2-type 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219160_209465826.0DomainNote=LRRCT
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219210_300465826.0DomainNote=Ig-like C2-type 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219309_382465826.0DomainNote=Ig-like C2-type 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014160_209465613.0DomainNote=LRRCT
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014210_300465613.0DomainNote=Ig-like C2-type 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014309_382465613.0DomainNote=Ig-like C2-type 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115104_125465613.0RepeatNote=LRR 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115128_149465613.0RepeatNote=LRR 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118104_125465826.0RepeatNote=LRR 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118128_149465826.0RepeatNote=LRR 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119104_125465840.0RepeatNote=LRR 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119128_149465840.0RepeatNote=LRR 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219104_125465826.0RepeatNote=LRR 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219128_149465826.0RepeatNote=LRR 2
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014104_125465613.0RepeatNote=LRR 1
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014128_149465613.0RepeatNote=LRR 2
TgeneNTRK3chr2:42491871chr15:88576276ENST00000317501111532_429465613.0Topological domainExtracellular
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115454_839465613.0Topological domainCytoplasmic
TgeneNTRK3chr2:42491871chr15:88576276ENST00000355254111832_429465826.0Topological domainExtracellular
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118454_839465826.0Topological domainCytoplasmic
TgeneNTRK3chr2:42491871chr15:88576276ENST00000360948111932_429465840.0Topological domainExtracellular
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119454_839465840.0Topological domainCytoplasmic
TgeneNTRK3chr2:42491871chr15:88576276ENST00000394480121932_429465826.0Topological domainExtracellular
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219454_839465826.0Topological domainCytoplasmic
TgeneNTRK3chr2:42491871chr15:88576276ENST00000540489101432_429465613.0Topological domainExtracellular
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014454_839465613.0Topological domainCytoplasmic
TgeneNTRK3chr2:42491871chr15:88576276ENST000003175011115430_453465613.0TransmembraneHelical
TgeneNTRK3chr2:42491871chr15:88576276ENST000003552541118430_453465826.0TransmembraneHelical
TgeneNTRK3chr2:42491871chr15:88576276ENST000003609481119430_453465840.0TransmembraneHelical
TgeneNTRK3chr2:42491871chr15:88576276ENST000003944801219430_453465826.0TransmembraneHelical
TgeneNTRK3chr2:42491871chr15:88576276ENST000005404891014430_453465613.0TransmembraneHelical


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Fusion Gene Sequence for EML4-NTRK3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>26468_26468_1_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000317501_length(transcript)=3350nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTGGGTCTTTTCAAACATAGACAATCATGGGATATTAAACTTGAAGGACAATAG
AGATCATCTAGTCCCATCAACTCACTATATATATGAGGAACCTGAGGTCCAGAGTGGGGAAGTGTCTTACCCAAGGTCACATGGTTTCAG
AGAAATTATGTTGAATCCAATAAGCCTTCCCGGACATTCCAAGCCTCTTAACCATGGCATCTATGTTGAGGATGTCAATGTTTATTTCAG
CAAAGGACGTCATGGCTTTTAAAAACTCCTTTTAAGCCTCCTTGTTTTGATGTCACCTTGGTAGGCTGGGCCCTCTGAGAGGTTGGAAGC
TCTAGGCATTGTTCTCTTTGGATCCAGGGATGCTAAGTAGAAACTGCATGAGCCACCAGTGCCCCGGCACCCTTTAACACCACCAGATGG
GTGTTTTCCCCCATCCACCACTGGCAGGGTTGCCCCTTCCCTCCAATCATCACTGTGCTCCTTTTTTCCCGGCCTACGAGGCAGCTCCTG
CCACTATCTTTAGAGCCAATAAAGAGAATTAAAAACCTGTGCACCAGGAGCATCTTTTAAATACACTAGCCATTCTCTTGCTTTACAAAA
ACAACCTAACCATCACAAGAAAGCCTGATGAAGTCCAGCCGTGCTCCAGCCTCACTTTCCCTGCTTGGAAGCGTGGGGTCTCCCTGGCTC
TCCCAGGATACCATGCTGTCCTCTTAGTGACCTCGTCGCCCTGCAACCTCCAGTGGGGAAGAGTCACAGAGAGCACCTAAGCAGAGGTGG
AGACGGCGCGGTAAGAGGAGGGGGAGCCAGGCTCAAGTATTGGCACCAAGTTAGGTCTCAGAGGAAAGAATGGAAACCAATCACTTTACA
TTTTTATTTTTATTTTCGGTGGAAAAATCATCCTTTTTTGGGACATACTTGCCCCCTACTTCCTCTTCTCTCTGGAACGGCTCACAATGA
GTGTGACATTAGAAAACTCCTTGCAGAGGAGAGTTTCTCCAGGCTCTTCCTGGGCCCTTAGATCTGCAGTTCCGACAAGCTTTGGCTGCA
GGAGGTTTTACCCATGAACTGGCCATCCTACTAGGACCACAAGGGACCAAGGGAATCAGGGACAAAGGCCCTTCCTGCCAGCCCATGATC
CCGGGATTGGCTCTCTTCCCCTACTTCCACTTATTCTTGACTCTGAGAACTTTTGGAACCCAATGGAATCAGCATTTCAAGGTCAAGATG
AACTGAAGGGGAAGAGAAGTAAAACTTGGCCTCCTCCAGCCCCTCTCATGGCACCAATGGAAGTGTCCTCCTGTTCTCTGGTCAATATGT
GTGTTTACTTTGCTTGCTTTGACTCATGCCTTACTCCATGGCCACCCTCTCCCAAAGAGGGGGCTCGCTTCCCCCATTTTCAACTTGATC
CACTGAGGAGAGGGAAGGGGGTGACTTTCCCTTCTTCAGTAGGAAAGGCACATTTGTAGGGCCTGAAACTCTCCCGTATTTGCTGACTCA
TTGGTGGAGTAGACTTCTGGCTCCCAGCTCCACTGGCCCATGGGGCCTCCATTGTATGAAGTCAGCATAGGCTGCCCACCTAATGGTGGA
GAGCATGAAACTGGGAGCATCCTGTGGGGGGCTTGTGGGGGAAAAAGGTGGTTGTTTTAACCCACCGTTGTTTTGGGGTGGTGTTGCACA
CTAGTAGAGAATAGAGTCTATGCCTTTGGCAAATTTAACTGGGAGTTTGGATTCCCACTTAAGGGTTTTACTTCTTGGGTCCTGTGGATG
GTGGTTCTTCGTGTCAGGATCCCAGCCCGATTCTGCAAATGCCTCCATGGGGTTTAAAAACATGAGGCTTTCCAAGTTCTTGCCCAGTAT
CTGGGGCAGCCTCCAGAGTATCACCTGGGAGTTCAGGTTCTCTCCAGGGCTCCAGGTGTGTGTTTATCTCGCCCCCTCCAGCTCTCCTCA
TCCTGCTCCCCATTGCTCCATGTCAGGCTGTTCCCCATTGTGCCCTGCTGATGCTTTGGGTCCAGGGCCTCCTCCCAAGTGTGGCTTTAA
GGAGTAAGCTTGAGGATGATGTTTTTTAATTATTGTAAATCATTACCTCATTTCCAGCCTCCCAGGCTCCATCCATCCCAGCATCTTTTA
TTCTGCCATTTTCCTCACCTTGTGCTATGACAATGGGGCGTTGTGTTTCCACAGAGACTTATAGGAGTGTTCAGTGTATAGTTTCTTAAT

>26468_26468_1_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000317501_length(amino acids)=369AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTWVFSNIDNHGILNLKDNRDHLVPSTHYIYEEPEVQSGEVSYPRSHGFREIMLNPISLPGHSKPLNHGIYVEDVNV

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>26468_26468_2_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000355254_length(transcript)=2155nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGA
AAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCC
ATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTA
CGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGC
CACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCT

>26468_26468_2_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000355254_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_3_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000357724_length(transcript)=2197nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGAGGT
GGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTT
CGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGG
TCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAA
CATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCAT
GAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTT

>26468_26468_3_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000357724_length(amino acids)=596AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECI

--------------------------------------------------------------
>26468_26468_4_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000360948_length(transcript)=2197nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGAGGT
GGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTT
CGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGG
TCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAA
CATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCAT
GAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTT

>26468_26468_4_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000360948_length(amino acids)=596AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECI

--------------------------------------------------------------
>26468_26468_5_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000394480_length(transcript)=3947nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGA
AAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCC
ATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTA
CGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGC
CACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCT
CCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTTCATATAAACTCAAGTGCCTGCTACACATACAACACTGAAAAA
AGGAAAAAAAAAGAAAGAAAAAAAAACCCTGTAAGGCAGTTTGGCAAATATATATATATATATATATATTTATATATCTAACTATCTATC
AATCTATATCTACAGAGAGTTACCTTCTCTAGTACACAGAGAAGCTGCTGATACAGAAAACCACAAGACTTTAACAACTCAGAAACTCTA
AAATATTAATAATACAAAGGAAAATTCCCTTTGACTTAAGCTGTGGCCCATGCTTCTAATGCTACGGCTCTTTGGAGCAGAAGACCTGGA
CCATGCAGAGAGACAATCTTTGGGATGAGAGCTCTGGGACGGGAGGAGTTAAGGTGGTGCTCAGTCGCTGCTGTGTGTGTCTGTTACCCC
GGAAGCTCACCACAGGCACATGTGGGGACTGCATGGCTGTGCTCAGCAAAGAAATGATGCCTGAGCAGGGTCCTTGCCTCCACTTCTTCC
CCATTTCCTCCACTTCAGGACAATGTTCTAATTTGTCCATTCTAAAAAGTGTAATCTTGATGCTTTTGGGAATCAATGATGGCACCTACG
GGTAAACACAGAACAGACAACCCCACAACACAAAACCATGACAAGAGCTGACAGCATCCATCCTGGGTGTAAGCTTCTTGCTGGAGTTGC
AAAGGATGTGTCTTTCTATTCTCAGAACTTAAAGAACTGGACTTTCTGGAGTAAAAGAACCACAGAAGAAAAAATAGCTGAAACCTGAAC
CCTGCCAAGACACTGCCACCTGTCTTTTCCATCATTGCAAAGATTCCTTGGCCTCACCTCCCACTTTCAGGCCCCTGGGAAGCTTAGGGG
GTTAGGAAACAGGTCCCCATGTTATCTTTGAATGTAGACACAGCACGCTTTAGGGTTGCAATAGCAAGAGACTTGGTTGCTTGTAGGTCA
TTATAACGAATGCCCCCTGGTCCTCTCAGTTTCTCATCCTGCTTCCCTAGATCCTAGACCCCACTTCCTGGGTCTCTACTGAGTCCCAGG
TAAACCCCACTGCCAAGGAAGGGAGCCAGGTCTAGTGAGAGGCTGCAGCAGTGAGTGTTTCAGGAAAGCAAGCAGTGGAGTGGGTGAGAG
CCAGCAGGGGAGAATCTACTTGGCACCTGTGCCAGGCCCCTTGGCATTCTCCTCACGTTTCCAGCCCCTGGGAGGATTGATGCATCTGCC
TTTGAGCTGTTGTGAAAACGCAGGGGCTGAGAAATCACTTTTGTGGGCTGGGGTAGGGGGAAGGGCTGAGGCTTCTCTGGGAGATGTCCA
ATGAGCGGCCAGTGCTGCAGGCTTGGAATCTTAATGAGGCCTGAGCCCTGACCGGAGAGAGGGAAGGAAACATCTGTGCTGGGGCCTGCT
CCCTCTGCCCCAGCACTGGGGAATCACTGCCTTCCTGGCTGCTGCCACATACCACAGTGGGGCCGACCTCTGGGCCTCCCTGTCACATGA
AACATGGAAGCCAACAGCCTGGCCCCACAGATCTCCTCTGCTGGAGAGGAGAGGATGTGTTCCTCCCAGGCCACGGGGCCCCTCTGCCTT
GCCCCAAGCACAGAGCTACCTAAGGGACTGACCTTTGCCACACTGGAGCTCACCTCCCGGGGGCCTCTGGCCTACCCTTTTCCCTGCCAG
CTGAAGAGACTGCCGGCAGCCTGGACGTCCTGGTTAGCTGAAGGCAGCTGAAATGTGGGCCTCCCTATGTGGGGTTTAGTACTGAATTAT

>26468_26468_5_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000394480_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_6_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000542733_length(transcript)=1954nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTTGTGCAGGCATGAGGACTGATACTGGGGAAAAAAGACGGGGA
AGATGCCCCATAAGAAAATTCTGAGACGTTGAAGCATGCTTATATTGGATTCTGTCCTCGGGAAAGGAGAGGAAAAGGCTGAAGGAGACC
ATTGAATCTGGTGTTGAGTCATTCACGTCTCTCTACTCCTGTGGAGGGCCCTTACGGATGTGTCATAACAGGATCTCCTTTTCCTTCCTC

>26468_26468_6_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000542733_length(amino acids)=472AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV

--------------------------------------------------------------
>26468_26468_7_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000557856_length(transcript)=2155nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGA
AAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCC
ATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTA
CGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGC
CACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCT

>26468_26468_7_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000557856_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_8_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000558676_length(transcript)=1855nt_BP=929nt
GGCGCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGC
GGCCGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCA
GGCTCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGG
TTTCGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCA
ACAAGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAA
AAAATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACC
AAGTCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACA
AGGACAGAGAGAAAAAAAAGAGGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACC
TCTCCAAATACACAGACAAACTCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAA
TTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGA
CAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCA
CGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTA
CTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGA
GGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGA
TCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGT
GTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGC
AATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGG
TATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGG
GGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTAAAGTGACTTTCCCAGCTGCAGGACTCAGCCACAGAGCTAGC
GCCTTGCTTACATGTCTTTTTCATTGTCCATTAACCCTGTCACTCTGGCACACACATATACACACCCATGCCCAGACATGCACTCAACAG

>26468_26468_8_EML4-NTRK3_EML4_chr2_42491871_ENST00000318522_NTRK3_chr15_88576276_ENST00000558676_length(amino acids)=470AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV

--------------------------------------------------------------
>26468_26468_9_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000317501_length(transcript)=3239nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTGGGTCTTTTCAAACATAGACAATCATGGGATATTAAACTTGAAGGACAATAGAGATCATCTAGTCCCATCAAC
TCACTATATATATGAGGAACCTGAGGTCCAGAGTGGGGAAGTGTCTTACCCAAGGTCACATGGTTTCAGAGAAATTATGTTGAATCCAAT
AAGCCTTCCCGGACATTCCAAGCCTCTTAACCATGGCATCTATGTTGAGGATGTCAATGTTTATTTCAGCAAAGGACGTCATGGCTTTTA
AAAACTCCTTTTAAGCCTCCTTGTTTTGATGTCACCTTGGTAGGCTGGGCCCTCTGAGAGGTTGGAAGCTCTAGGCATTGTTCTCTTTGG
ATCCAGGGATGCTAAGTAGAAACTGCATGAGCCACCAGTGCCCCGGCACCCTTTAACACCACCAGATGGGTGTTTTCCCCCATCCACCAC
TGGCAGGGTTGCCCCTTCCCTCCAATCATCACTGTGCTCCTTTTTTCCCGGCCTACGAGGCAGCTCCTGCCACTATCTTTAGAGCCAATA
AAGAGAATTAAAAACCTGTGCACCAGGAGCATCTTTTAAATACACTAGCCATTCTCTTGCTTTACAAAAACAACCTAACCATCACAAGAA
AGCCTGATGAAGTCCAGCCGTGCTCCAGCCTCACTTTCCCTGCTTGGAAGCGTGGGGTCTCCCTGGCTCTCCCAGGATACCATGCTGTCC
TCTTAGTGACCTCGTCGCCCTGCAACCTCCAGTGGGGAAGAGTCACAGAGAGCACCTAAGCAGAGGTGGAGACGGCGCGGTAAGAGGAGG
GGGAGCCAGGCTCAAGTATTGGCACCAAGTTAGGTCTCAGAGGAAAGAATGGAAACCAATCACTTTACATTTTTATTTTTATTTTCGGTG
GAAAAATCATCCTTTTTTGGGACATACTTGCCCCCTACTTCCTCTTCTCTCTGGAACGGCTCACAATGAGTGTGACATTAGAAAACTCCT
TGCAGAGGAGAGTTTCTCCAGGCTCTTCCTGGGCCCTTAGATCTGCAGTTCCGACAAGCTTTGGCTGCAGGAGGTTTTACCCATGAACTG
GCCATCCTACTAGGACCACAAGGGACCAAGGGAATCAGGGACAAAGGCCCTTCCTGCCAGCCCATGATCCCGGGATTGGCTCTCTTCCCC
TACTTCCACTTATTCTTGACTCTGAGAACTTTTGGAACCCAATGGAATCAGCATTTCAAGGTCAAGATGAACTGAAGGGGAAGAGAAGTA
AAACTTGGCCTCCTCCAGCCCCTCTCATGGCACCAATGGAAGTGTCCTCCTGTTCTCTGGTCAATATGTGTGTTTACTTTGCTTGCTTTG
ACTCATGCCTTACTCCATGGCCACCCTCTCCCAAAGAGGGGGCTCGCTTCCCCCATTTTCAACTTGATCCACTGAGGAGAGGGAAGGGGG
TGACTTTCCCTTCTTCAGTAGGAAAGGCACATTTGTAGGGCCTGAAACTCTCCCGTATTTGCTGACTCATTGGTGGAGTAGACTTCTGGC
TCCCAGCTCCACTGGCCCATGGGGCCTCCATTGTATGAAGTCAGCATAGGCTGCCCACCTAATGGTGGAGAGCATGAAACTGGGAGCATC
CTGTGGGGGGCTTGTGGGGGAAAAAGGTGGTTGTTTTAACCCACCGTTGTTTTGGGGTGGTGTTGCACACTAGTAGAGAATAGAGTCTAT
GCCTTTGGCAAATTTAACTGGGAGTTTGGATTCCCACTTAAGGGTTTTACTTCTTGGGTCCTGTGGATGGTGGTTCTTCGTGTCAGGATC
CCAGCCCGATTCTGCAAATGCCTCCATGGGGTTTAAAAACATGAGGCTTTCCAAGTTCTTGCCCAGTATCTGGGGCAGCCTCCAGAGTAT
CACCTGGGAGTTCAGGTTCTCTCCAGGGCTCCAGGTGTGTGTTTATCTCGCCCCCTCCAGCTCTCCTCATCCTGCTCCCCATTGCTCCAT
GTCAGGCTGTTCCCCATTGTGCCCTGCTGATGCTTTGGGTCCAGGGCCTCCTCCCAAGTGTGGCTTTAAGGAGTAAGCTTGAGGATGATG
TTTTTTAATTATTGTAAATCATTACCTCATTTCCAGCCTCCCAGGCTCCATCCATCCCAGCATCTTTTATTCTGCCATTTTCCTCACCTT

>26468_26468_9_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000317501_length(amino acids)=369AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTWVFSNIDNHGILNLKDNRDHLVPSTHYIYEEPEVQSGEVSYPRSHGFREIMLNPISLPGHSKPLNHGIYVEDVNV

--------------------------------------------------------------
>26468_26468_10_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000355254_length(transcript)=2044nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTT
CACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACAC
GGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTG
GCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACAT
TCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCT

>26468_26468_10_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000355254_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_11_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000357724_length(transcript)=2086nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGAGGTGGGAGGACACACCATGCTCCC
CATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGAT
CTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCG
AGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAAT
CCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTC
CTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTTCATATAAACTCAAGTGCCTGC

>26468_26468_11_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000357724_length(amino acids)=596AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECI

--------------------------------------------------------------
>26468_26468_12_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000360948_length(transcript)=2086nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGAGGTGGGAGGACACACCATGCTCCC
CATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGAT
CTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCG
AGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAAT
CCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTC
CTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTTCATATAAACTCAAGTGCCTGC

>26468_26468_12_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000360948_length(amino acids)=596AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECI

--------------------------------------------------------------
>26468_26468_13_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000394480_length(transcript)=3836nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTT
CACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACAC
GGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTG
GCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACAT
TCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCT
TCCATCCTTGACTGAAGCGAACATCTTCATATAAACTCAAGTGCCTGCTACACATACAACACTGAAAAAAGGAAAAAAAAAGAAAGAAAA
AAAAACCCTGTAAGGCAGTTTGGCAAATATATATATATATATATATATTTATATATCTAACTATCTATCAATCTATATCTACAGAGAGTT
ACCTTCTCTAGTACACAGAGAAGCTGCTGATACAGAAAACCACAAGACTTTAACAACTCAGAAACTCTAAAATATTAATAATACAAAGGA
AAATTCCCTTTGACTTAAGCTGTGGCCCATGCTTCTAATGCTACGGCTCTTTGGAGCAGAAGACCTGGACCATGCAGAGAGACAATCTTT
GGGATGAGAGCTCTGGGACGGGAGGAGTTAAGGTGGTGCTCAGTCGCTGCTGTGTGTGTCTGTTACCCCGGAAGCTCACCACAGGCACAT
GTGGGGACTGCATGGCTGTGCTCAGCAAAGAAATGATGCCTGAGCAGGGTCCTTGCCTCCACTTCTTCCCCATTTCCTCCACTTCAGGAC
AATGTTCTAATTTGTCCATTCTAAAAAGTGTAATCTTGATGCTTTTGGGAATCAATGATGGCACCTACGGGTAAACACAGAACAGACAAC
CCCACAACACAAAACCATGACAAGAGCTGACAGCATCCATCCTGGGTGTAAGCTTCTTGCTGGAGTTGCAAAGGATGTGTCTTTCTATTC
TCAGAACTTAAAGAACTGGACTTTCTGGAGTAAAAGAACCACAGAAGAAAAAATAGCTGAAACCTGAACCCTGCCAAGACACTGCCACCT
GTCTTTTCCATCATTGCAAAGATTCCTTGGCCTCACCTCCCACTTTCAGGCCCCTGGGAAGCTTAGGGGGTTAGGAAACAGGTCCCCATG
TTATCTTTGAATGTAGACACAGCACGCTTTAGGGTTGCAATAGCAAGAGACTTGGTTGCTTGTAGGTCATTATAACGAATGCCCCCTGGT
CCTCTCAGTTTCTCATCCTGCTTCCCTAGATCCTAGACCCCACTTCCTGGGTCTCTACTGAGTCCCAGGTAAACCCCACTGCCAAGGAAG
GGAGCCAGGTCTAGTGAGAGGCTGCAGCAGTGAGTGTTTCAGGAAAGCAAGCAGTGGAGTGGGTGAGAGCCAGCAGGGGAGAATCTACTT
GGCACCTGTGCCAGGCCCCTTGGCATTCTCCTCACGTTTCCAGCCCCTGGGAGGATTGATGCATCTGCCTTTGAGCTGTTGTGAAAACGC
AGGGGCTGAGAAATCACTTTTGTGGGCTGGGGTAGGGGGAAGGGCTGAGGCTTCTCTGGGAGATGTCCAATGAGCGGCCAGTGCTGCAGG
CTTGGAATCTTAATGAGGCCTGAGCCCTGACCGGAGAGAGGGAAGGAAACATCTGTGCTGGGGCCTGCTCCCTCTGCCCCAGCACTGGGG
AATCACTGCCTTCCTGGCTGCTGCCACATACCACAGTGGGGCCGACCTCTGGGCCTCCCTGTCACATGAAACATGGAAGCCAACAGCCTG
GCCCCACAGATCTCCTCTGCTGGAGAGGAGAGGATGTGTTCCTCCCAGGCCACGGGGCCCCTCTGCCTTGCCCCAAGCACAGAGCTACCT
AAGGGACTGACCTTTGCCACACTGGAGCTCACCTCCCGGGGGCCTCTGGCCTACCCTTTTCCCTGCCAGCTGAAGAGACTGCCGGCAGCC
TGGACGTCCTGGTTAGCTGAAGGCAGCTGAAATGTGGGCCTCCCTATGTGGGGTTTAGTACTGAATTATGTGTTTGTGGTTTTGCTTCTT

>26468_26468_13_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000394480_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_14_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000542733_length(transcript)=1843nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGGTTGTGCAGGCATGAGGACTGATACTGGGGAAAAAAGACGGGGAAGATGCCCCATAAGAAAATTC
TGAGACGTTGAAGCATGCTTATATTGGATTCTGTCCTCGGGAAAGGAGAGGAAAAGGCTGAAGGAGACCATTGAATCTGGTGTTGAGTCA
TTCACGTCTCTCTACTCCTGTGGAGGGCCCTTACGGATGTGTCATAACAGGATCTCCTTTTCCTTCCTCAAGTGCAAAAGGCCTTTTTTT

>26468_26468_14_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000542733_length(amino acids)=472AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV

--------------------------------------------------------------
>26468_26468_15_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000557856_length(transcript)=2044nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTT
CACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACAC
GGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTG
GCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACAT
TCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCT

>26468_26468_15_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000557856_length(amino acids)=582AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV
KIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGRVLERPRVCPK

--------------------------------------------------------------
>26468_26468_16_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000558676_length(transcript)=1744nt_BP=818nt
GGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGCTCAGCGTCGGCCACTCTG
TCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTTCGCCGGCAGTCTCGATGA
TAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACAAGAAGATGAAATCACTGT
GCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAAATCAGTCTCAAGTAAAGG
CCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAGTCATACCAGTGCTGTCTC
AATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGTGGTACAGAAAAAAAGAAAGAAAAACCACAAGGACAGAGAGAAAAAAAAGA
GGAATCTCATTCTAATGATCAAAGTCCACAAATTCGAGCATCACCTTCTCCCCAGCCCTCTTCACAACCTCTCCAAATACACAGACAAAC
TCCAGAAAGCAAGAATGCTACTCCCACCAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACATAATTCTTGGGAAAATTCAGATGA
TAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGCAGACAAGCATAAAGATGTCATCAT
CAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAACCACGGCATCACCACGCCCTCGTC
ACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCAGTACTTCCGTCAGGGACACAACTG
CCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGGTGAGGGAGCCTTTGGAAAGGTCTT
CCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAAGGATCCCACCCTGGCTGCCCGGAA
GGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGGAGTGTGCGGCGATGGGGACCCCCT
CATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGATGCAATGATCCTTGTGGATGGACA
GCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTCGGGTATGGTGTACCTGGCCTCCCA
GCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGATTGGGGACTTCGGCATGTCCAGAGA
TGTCTACAGCACGGATTATTACAGGGTAAAGTGACTTTCCCAGCTGCAGGACTCAGCCACAGAGCTAGCGCCTTGCTTACATGTCTTTTT
CATTGTCCATTAACCCTGTCACTCTGGCACACACATATACACACCCATGCCCAGACATGCACTCAACAGTTATCTTTTGGCCTCTCTTGC

>26468_26468_16_EML4-NTRK3_EML4_chr2_42491871_ENST00000401738_NTRK3_chr15_88576276_ENST00000558676_length(amino acids)=470AA_BP=222
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQTPESKNATPTKSIKRPSPAEK
SHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPLHHINHGITTPSSLDAGPDTVVIGMTRIPVIEN
PQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARKDFQREAELLTNLQHEHIVKF
YGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLV

--------------------------------------------------------------
>26468_26468_17_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000317501_length(transcript)=3173nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTGGGTCTTTTCAAACATAGACAATCATGGGATATTAAACTTGAAGGACAA
TAGAGATCATCTAGTCCCATCAACTCACTATATATATGAGGAACCTGAGGTCCAGAGTGGGGAAGTGTCTTACCCAAGGTCACATGGTTT
CAGAGAAATTATGTTGAATCCAATAAGCCTTCCCGGACATTCCAAGCCTCTTAACCATGGCATCTATGTTGAGGATGTCAATGTTTATTT
CAGCAAAGGACGTCATGGCTTTTAAAAACTCCTTTTAAGCCTCCTTGTTTTGATGTCACCTTGGTAGGCTGGGCCCTCTGAGAGGTTGGA
AGCTCTAGGCATTGTTCTCTTTGGATCCAGGGATGCTAAGTAGAAACTGCATGAGCCACCAGTGCCCCGGCACCCTTTAACACCACCAGA
TGGGTGTTTTCCCCCATCCACCACTGGCAGGGTTGCCCCTTCCCTCCAATCATCACTGTGCTCCTTTTTTCCCGGCCTACGAGGCAGCTC
CTGCCACTATCTTTAGAGCCAATAAAGAGAATTAAAAACCTGTGCACCAGGAGCATCTTTTAAATACACTAGCCATTCTCTTGCTTTACA
AAAACAACCTAACCATCACAAGAAAGCCTGATGAAGTCCAGCCGTGCTCCAGCCTCACTTTCCCTGCTTGGAAGCGTGGGGTCTCCCTGG
CTCTCCCAGGATACCATGCTGTCCTCTTAGTGACCTCGTCGCCCTGCAACCTCCAGTGGGGAAGAGTCACAGAGAGCACCTAAGCAGAGG
TGGAGACGGCGCGGTAAGAGGAGGGGGAGCCAGGCTCAAGTATTGGCACCAAGTTAGGTCTCAGAGGAAAGAATGGAAACCAATCACTTT
ACATTTTTATTTTTATTTTCGGTGGAAAAATCATCCTTTTTTGGGACATACTTGCCCCCTACTTCCTCTTCTCTCTGGAACGGCTCACAA
TGAGTGTGACATTAGAAAACTCCTTGCAGAGGAGAGTTTCTCCAGGCTCTTCCTGGGCCCTTAGATCTGCAGTTCCGACAAGCTTTGGCT
GCAGGAGGTTTTACCCATGAACTGGCCATCCTACTAGGACCACAAGGGACCAAGGGAATCAGGGACAAAGGCCCTTCCTGCCAGCCCATG
ATCCCGGGATTGGCTCTCTTCCCCTACTTCCACTTATTCTTGACTCTGAGAACTTTTGGAACCCAATGGAATCAGCATTTCAAGGTCAAG
ATGAACTGAAGGGGAAGAGAAGTAAAACTTGGCCTCCTCCAGCCCCTCTCATGGCACCAATGGAAGTGTCCTCCTGTTCTCTGGTCAATA
TGTGTGTTTACTTTGCTTGCTTTGACTCATGCCTTACTCCATGGCCACCCTCTCCCAAAGAGGGGGCTCGCTTCCCCCATTTTCAACTTG
ATCCACTGAGGAGAGGGAAGGGGGTGACTTTCCCTTCTTCAGTAGGAAAGGCACATTTGTAGGGCCTGAAACTCTCCCGTATTTGCTGAC
TCATTGGTGGAGTAGACTTCTGGCTCCCAGCTCCACTGGCCCATGGGGCCTCCATTGTATGAAGTCAGCATAGGCTGCCCACCTAATGGT
GGAGAGCATGAAACTGGGAGCATCCTGTGGGGGGCTTGTGGGGGAAAAAGGTGGTTGTTTTAACCCACCGTTGTTTTGGGGTGGTGTTGC
ACACTAGTAGAGAATAGAGTCTATGCCTTTGGCAAATTTAACTGGGAGTTTGGATTCCCACTTAAGGGTTTTACTTCTTGGGTCCTGTGG
ATGGTGGTTCTTCGTGTCAGGATCCCAGCCCGATTCTGCAAATGCCTCCATGGGGTTTAAAAACATGAGGCTTTCCAAGTTCTTGCCCAG
TATCTGGGGCAGCCTCCAGAGTATCACCTGGGAGTTCAGGTTCTCTCCAGGGCTCCAGGTGTGTGTTTATCTCGCCCCCTCCAGCTCTCC
TCATCCTGCTCCCCATTGCTCCATGTCAGGCTGTTCCCCATTGTGCCCTGCTGATGCTTTGGGTCCAGGGCCTCCTCCCAAGTGTGGCTT
TAAGGAGTAAGCTTGAGGATGATGTTTTTTAATTATTGTAAATCATTACCTCATTTCCAGCCTCCCAGGCTCCATCCATCCCAGCATCTT
TTATTCTGCCATTTTCCTCACCTTGTGCTATGACAATGGGGCGTTGTGTTTCCACAGAGACTTATAGGAGTGTTCAGTGTATAGTTTCTT

>26468_26468_17_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000317501_length(amino acids)=311AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTWVFSNIDNHGILNLKDNRDHLVPSTHYIYEEPEVQSGEVSYPR

--------------------------------------------------------------
>26468_26468_18_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000355254_length(transcript)=1978nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCC
TGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCA
GCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGT
GTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAA
GGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACA

>26468_26468_18_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000355254_length(amino acids)=524AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS
QIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT

--------------------------------------------------------------
>26468_26468_19_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000357724_length(transcript)=2020nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGA
GGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAG
CTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCA
AGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTT
GAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGT
CATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACAT

>26468_26468_19_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000357724_length(amino acids)=538AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS
QIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTES

--------------------------------------------------------------
>26468_26468_20_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000360948_length(transcript)=2020nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGCTCTTTAATCCATCTGGAAATGATTTTTGTATATGGTGTGA
GGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCCTGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAG
CTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCAGCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCA
AGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGTGTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTT
GAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAAGGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGT
CATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACATCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACAT

>26468_26468_20_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000360948_length(amino acids)=538AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS
QIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTES

--------------------------------------------------------------
>26468_26468_21_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000394480_length(transcript)=3770nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCC
TGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCA
GCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGT
GTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAA
GGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACA
TCTCCCTTCCACCTCACAACTCCTTCCATCCTTGACTGAAGCGAACATCTTCATATAAACTCAAGTGCCTGCTACACATACAACACTGAA
AAAAGGAAAAAAAAAGAAAGAAAAAAAAACCCTGTAAGGCAGTTTGGCAAATATATATATATATATATATATTTATATATCTAACTATCT
ATCAATCTATATCTACAGAGAGTTACCTTCTCTAGTACACAGAGAAGCTGCTGATACAGAAAACCACAAGACTTTAACAACTCAGAAACT
CTAAAATATTAATAATACAAAGGAAAATTCCCTTTGACTTAAGCTGTGGCCCATGCTTCTAATGCTACGGCTCTTTGGAGCAGAAGACCT
GGACCATGCAGAGAGACAATCTTTGGGATGAGAGCTCTGGGACGGGAGGAGTTAAGGTGGTGCTCAGTCGCTGCTGTGTGTGTCTGTTAC
CCCGGAAGCTCACCACAGGCACATGTGGGGACTGCATGGCTGTGCTCAGCAAAGAAATGATGCCTGAGCAGGGTCCTTGCCTCCACTTCT
TCCCCATTTCCTCCACTTCAGGACAATGTTCTAATTTGTCCATTCTAAAAAGTGTAATCTTGATGCTTTTGGGAATCAATGATGGCACCT
ACGGGTAAACACAGAACAGACAACCCCACAACACAAAACCATGACAAGAGCTGACAGCATCCATCCTGGGTGTAAGCTTCTTGCTGGAGT
TGCAAAGGATGTGTCTTTCTATTCTCAGAACTTAAAGAACTGGACTTTCTGGAGTAAAAGAACCACAGAAGAAAAAATAGCTGAAACCTG
AACCCTGCCAAGACACTGCCACCTGTCTTTTCCATCATTGCAAAGATTCCTTGGCCTCACCTCCCACTTTCAGGCCCCTGGGAAGCTTAG
GGGGTTAGGAAACAGGTCCCCATGTTATCTTTGAATGTAGACACAGCACGCTTTAGGGTTGCAATAGCAAGAGACTTGGTTGCTTGTAGG
TCATTATAACGAATGCCCCCTGGTCCTCTCAGTTTCTCATCCTGCTTCCCTAGATCCTAGACCCCACTTCCTGGGTCTCTACTGAGTCCC
AGGTAAACCCCACTGCCAAGGAAGGGAGCCAGGTCTAGTGAGAGGCTGCAGCAGTGAGTGTTTCAGGAAAGCAAGCAGTGGAGTGGGTGA
GAGCCAGCAGGGGAGAATCTACTTGGCACCTGTGCCAGGCCCCTTGGCATTCTCCTCACGTTTCCAGCCCCTGGGAGGATTGATGCATCT
GCCTTTGAGCTGTTGTGAAAACGCAGGGGCTGAGAAATCACTTTTGTGGGCTGGGGTAGGGGGAAGGGCTGAGGCTTCTCTGGGAGATGT
CCAATGAGCGGCCAGTGCTGCAGGCTTGGAATCTTAATGAGGCCTGAGCCCTGACCGGAGAGAGGGAAGGAAACATCTGTGCTGGGGCCT
GCTCCCTCTGCCCCAGCACTGGGGAATCACTGCCTTCCTGGCTGCTGCCACATACCACAGTGGGGCCGACCTCTGGGCCTCCCTGTCACA
TGAAACATGGAAGCCAACAGCCTGGCCCCACAGATCTCCTCTGCTGGAGAGGAGAGGATGTGTTCCTCCCAGGCCACGGGGCCCCTCTGC
CTTGCCCCAAGCACAGAGCTACCTAAGGGACTGACCTTTGCCACACTGGAGCTCACCTCCCGGGGGCCTCTGGCCTACCCTTTTCCCTGC
CAGCTGAAGAGACTGCCGGCAGCCTGGACGTCCTGGTTAGCTGAAGGCAGCTGAAATGTGGGCCTCCCTATGTGGGGTTTAGTACTGAAT

>26468_26468_21_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000394480_length(amino acids)=524AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS
QIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT

--------------------------------------------------------------
>26468_26468_22_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000542733_length(transcript)=1777nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTTGTGCAGGCATGAGGACTGATACTGGGGAAAAAAGACGG
GGAAGATGCCCCATAAGAAAATTCTGAGACGTTGAAGCATGCTTATATTGGATTCTGTCCTCGGGAAAGGAGAGGAAAAGGCTGAAGGAG
ACCATTGAATCTGGTGTTGAGTCATTCACGTCTCTCTACTCCTGTGGAGGGCCCTTACGGATGTGTCATAACAGGATCTCCTTTTCCTTC

>26468_26468_22_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000542733_length(amino acids)=414AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS

--------------------------------------------------------------
>26468_26468_23_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000557856_length(transcript)=1978nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTGGGAGGACACACCATGCTCCCCATTCGCTGGATGCCTCC
TGAAAGCATCATGTACCGGAAGTTCACTACAGAGAGTGATGTATGGAGCTTCGGGGTGATCCTCTGGGAGATCTTCACCTATGGAAAGCA
GCCATGGTTCCAACTCTCAAACACGGAGGTCATTGAGTGCATTACCCAAGGTCGTGTTTTGGAGCGGCCCCGAGTCTGCCCCAAAGAGGT
GTACGATGTCATGCTGGGGTGCTGGCAGAGGGAACCACAGCAGCGGTTGAACATCAAGGAGATCTACAAAATCCTCCATGCTTTGGGGAA
GGCCACCCCAATCTACCTGGACATTCTTGGCTAGTGGTGGCTGGTGGTCATGAATTCATACTCTGTTGCCTCCTCTCTCCCTGCCTCACA

>26468_26468_23_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000557856_length(amino acids)=524AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS
QIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFT

--------------------------------------------------------------
>26468_26468_24_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000558676_length(transcript)=1678nt_BP=752nt
GCGGCGCTCGCGGCTGCTGCCTGGGAGGGAGGCCGGGCAGGCGGCTGAGCGGCGCGGCTCTCAACGTGACGGGGAAGTGGTTCGGGCGGC
CGCGGCTTACTACCCCAGGGCGAACGGACGGACGACGGAGGCGGGAGCCGGTAGCCGAGCCGGGCGACCTAGAGAACGAGCGGGTCAGGC
TCAGCGTCGGCCACTCTGTCGGTCCGCTGAATGAAGTGCCCGCCCCTCTAAGCCCGGAGCCCGGCGCTTTCCCCGCAAGATGGACGGTTT
CGCCGGCAGTCTCGATGATAGTATTTCTGCTGCAAGTACTTCTGATGTTCAAGATCGCCTGTCAGCTCTTGAGTCACGAGTTCAGCAACA
AGAAGATGAAATCACTGTGCTAAAGGCGGCTTTGGCTGATGTTTTGAGGCGTCTTGCAATCTCTGAAGATCATGTGGCCTCAGTGAAAAA
ATCAGTCTCAAGTAAAGGCCAACCAAGCCCTCGAGCAGTTATTCCCATGTCCTGTATAACCAATGGAAGTGGTGCAAACAGAAAACCAAG
TCATACCAGTGCTGTCTCAATTGCAGGAAAAGAAACTCTTTCATCTGCTGCTAAAAGCATAAAACGACCATCACCAGCTGAAAAGTCACA
TAATTCTTGGGAAAATTCAGATGATAGCCGTAATAAATTGTCGAAAATACCTTCAACACCCAAATTAATACCAAAAGTTACCAAAACTGC
AGACAAGCATAAAGATGTCATCATCAACCAAGGTCCCGTGGCTGTCATCAGTGGTGAGGAGGACTCAGCCAGCCCACTGCACCACATCAA
CCACGGCATCACCACGCCCTCGTCACTGGATGCCGGGCCCGACACTGTGGTCATTGGCATGACTCGCATCCCTGTCATTGAGAACCCCCA
GTACTTCCGTCAGGGACACAACTGCCACAAGCCGGACACGTATGTGCAGCACATTAAGAGGAGAGACATCGTGCTGAAGCGAGAACTGGG
TGAGGGAGCCTTTGGAAAGGTCTTCCTGGCCGAGTGCTACAACCTCAGCCCGACCAAGGACAAGATGCTTGTGGCTGTGAAGGCCCTGAA
GGATCCCACCCTGGCTGCCCGGAAGGATTTCCAGAGGGAGGCCGAGCTGCTCACCAACCTGCAGCATGAGCACATTGTCAAGTTCTATGG
AGTGTGCGGCGATGGGGACCCCCTCATCATGGTCTTTGAATACATGAAGCATGGAGACCTGAATAAGTTCCTCAGGGCCCATGGGCCAGA
TGCAATGATCCTTGTGGATGGACAGCCACGCCAGGCCAAGGGTGAGCTGGGGCTCTCCCAAATGCTCCACATTGCCAGTCAGATCGCCTC
GGGTATGGTGTACCTGGCCTCCCAGCACTTTGTGCACCGAGACCTGGCCACCAGGAACTGCCTGGTTGGAGCGAATCTGCTAGTGAAGAT
TGGGGACTTCGGCATGTCCAGAGATGTCTACAGCACGGATTATTACAGGGTAAAGTGACTTTCCCAGCTGCAGGACTCAGCCACAGAGCT
AGCGCCTTGCTTACATGTCTTTTTCATTGTCCATTAACCCTGTCACTCTGGCACACACATATACACACCCATGCCCAGACATGCACTCAA

>26468_26468_24_EML4-NTRK3_EML4_chr2_42491871_ENST00000402711_NTRK3_chr15_88576276_ENST00000558676_length(amino acids)=412AA_BP=164
MDGFAGSLDDSISAASTSDVQDRLSALESRVQQQEDEITVLKAALADVLRRLAISEDHVASVKKSVSSKGQPSPRAVIPMSCITNGSGAN
RKPSHTSAVSIAGKETLSSAAKSIKRPSPAEKSHNSWENSDDSRNKLSKIPSTPKLIPKVTKTADKHKDVIINQGPVAVISGEEDSASPL
HHINHGITTPSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAV
KALKDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAMILVDGQPRQAKGELGLSQMLHIAS

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Fusion Gene PPI Analysis for EML4-NTRK3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EML4-NTRK3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneNTRK3Q16288DB11986EntrectinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB11986EntrectinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB14723LarotrectinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB14723LarotrectinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB15822PralsetinibInhibitorSmall moleculeApproved|Investigational
TgeneNTRK3Q16288DB15822PralsetinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for EML4-NTRK3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEML4C0007131Non-Small Cell Lung Carcinoma6CTD_human
HgeneEML4C0027627Neoplasm Metastasis2CTD_human
HgeneEML4C0152013Adenocarcinoma of lung (disorder)2CTD_human
HgeneEML4C0006118Brain Neoplasms1CTD_human
HgeneEML4C0153633Malignant neoplasm of brain1CTD_human
HgeneEML4C0496899Benign neoplasm of brain, unspecified1CTD_human
HgeneEML4C0750974Brain Tumor, Primary1CTD_human
HgeneEML4C0750977Recurrent Brain Neoplasm1CTD_human
HgeneEML4C0750979Primary malignant neoplasm of brain1CTD_human
HgeneEML4C1527390Neoplasms, Intracranial1CTD_human
TgeneC0036341Schizophrenia3PSYGENET
TgeneC0041696Unipolar Depression2PSYGENET
TgeneC1269683Major Depressive Disorder2PSYGENET
TgeneC1332965Congenital Mesoblastic Nephroma2ORPHANET
TgeneC0014175Endometriosis1CTD_human
TgeneC0017638Glioma1CTD_human
TgeneC0019569Hirschsprung Disease1GENOMICS_ENGLAND
TgeneC0023467Leukemia, Myelocytic, Acute1CTD_human
TgeneC0026998Acute Myeloid Leukemia, M11CTD_human
TgeneC0038220Status Epilepticus1CTD_human
TgeneC0238463Papillary thyroid carcinoma1ORPHANET
TgeneC0259783mixed gliomas1CTD_human
TgeneC0269102Endometrioma1CTD_human
TgeneC0270823Petit mal status1CTD_human
TgeneC0311335Grand Mal Status Epilepticus1CTD_human
TgeneC0393734Complex Partial Status Epilepticus1CTD_human
TgeneC0525045Mood Disorders1PSYGENET
TgeneC0555198Malignant Glioma1CTD_human
TgeneC0751522Status Epilepticus, Subclinical1CTD_human
TgeneC0751523Non-Convulsive Status Epilepticus1CTD_human
TgeneC0751524Simple Partial Status Epilepticus1CTD_human
TgeneC1879321Acute Myeloid Leukemia (AML-M2)1CTD_human