Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:HMBS-EHBP1 (FusionGDB2 ID:HG3145TG23301)

Fusion Gene Summary for HMBS-EHBP1

Fusion gene summary

Fusion gene information	Fusion gene name: HMBS-EHBP1
	Fusion gene ID: hg3145tg23301
		Hgene	Tgene
	Gene symbol	HMBS	EHBP1
	Gene ID	3145	23301
	Gene name	hydroxymethylbilane synthase	EH domain binding protein 1
	Synonyms	PBG-D\|PBGD\|PORC\|UPS	HPC12\|NACSIN
	Cytomap	('HMBS')('EHBP1') 11q23.3	2p15
	Type of gene	protein-coding	protein-coding
	Description	porphobilinogen deaminaseporphyria, acute; Chester typepre-uroporphyrinogen synthaseuroporphyrinogen I synthaseuroporphyrinogen I synthetase	EH domain-binding protein 1NPF calponin-like proteintestis tissue sperm-binding protein Li 50e
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000278715, ENST00000392841, ENST00000442944, ENST00000537841, ENST00000542729, ENST00000543090, ENST00000544387, ENST00000534956,
Fusion gene scores	* DoF score	2 X 3 X 2=12	9 X 10 X 5=450
	# samples	2	10
	** MAII score	log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(10/450*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: HMBS [Title/Abstract] AND EHBP1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	HMBS(118963521)-EHBP1(63053222), # samples:2
Anticipated loss of major functional domain due to fusion event.	HMBS-EHBP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. HMBS-EHBP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. HMBS-EHBP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. HMBS-EHBP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across HMBS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across EHBP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-D8-A147-01A	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
ChimerDB4	BRCA	TCGA-D8-A147-01A	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+

Top

Fusion Gene ORF analysis for HMBS-EHBP1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000278715	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000278715	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000392841	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000392841	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000442944	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000442944	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000537841	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000537841	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000542729	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000542729	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000543090	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000543090	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000544387	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
5CDS-intron	ENST00000544387	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000278715	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000392841	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000442944	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000537841	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000542729	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000543090	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
In-frame	ENST00000544387	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-3CDS	ENST00000534956	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+
intron-intron	ENST00000534956	ENST00000496857	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+
intron-intron	ENST00000534956	ENST00000496857	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000278715	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4244	976	151	4146	1331
ENST00000278715	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	5134	976	151	4146	1331
ENST00000278715	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5239	976	151	4254	1367
ENST00000278715	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5347	976	151	4359	1402
ENST00000278715	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4255	976	151	4254	1368
ENST00000537841	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4333	1065	219	4235	1338
ENST00000537841	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	5223	1065	219	4235	1338
ENST00000537841	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5328	1065	219	4343	1374
ENST00000537841	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5436	1065	219	4448	1409
ENST00000537841	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4344	1065	219	4343	1374
ENST00000542729	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4213	945	219	4115	1298
ENST00000542729	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	5103	945	219	4115	1298
ENST00000542729	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5208	945	219	4223	1334
ENST00000542729	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5316	945	219	4328	1369
ENST00000542729	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4224	945	219	4223	1334
ENST00000442944	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4305	1037	263	4207	1314
ENST00000442944	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	5195	1037	263	4207	1314
ENST00000442944	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5300	1037	263	4315	1350
ENST00000442944	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5408	1037	263	4420	1385
ENST00000442944	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4316	1037	263	4315	1351
ENST00000544387	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4093	825	120	3995	1291
ENST00000544387	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	4983	825	120	3995	1291
ENST00000544387	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5088	825	120	4103	1327
ENST00000544387	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5196	825	120	4208	1362
ENST00000544387	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4104	825	120	4103	1327
ENST00000543090	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4104	836	104	4006	1300
ENST00000543090	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	4994	836	104	4006	1300
ENST00000543090	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5099	836	104	4114	1336
ENST00000543090	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5207	836	104	4219	1371
ENST00000543090	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4115	836	104	4114	1337
ENST00000392841	HMBS	chr11	118963521	+	ENST00000405015	EHBP1	chr2	63053222	+	4152	884	110	4054	1314
ENST00000392841	HMBS	chr11	118963521	+	ENST00000431489	EHBP1	chr2	63053222	+	5042	884	110	4054	1314
ENST00000392841	HMBS	chr11	118963521	+	ENST00000354487	EHBP1	chr2	63053222	+	5147	884	110	4162	1350
ENST00000392841	HMBS	chr11	118963521	+	ENST00000263991	EHBP1	chr2	63053222	+	5255	884	110	4267	1385
ENST00000392841	HMBS	chr11	118963521	+	ENST00000405289	EHBP1	chr2	63053222	+	4163	884	110	4162	1351
ENST00000278715	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4331	1063	151	4233	1360
ENST00000278715	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5221	1063	151	4233	1360
ENST00000278715	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5326	1063	151	4341	1396
ENST00000278715	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5434	1063	151	4446	1431
ENST00000278715	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4342	1063	151	4341	1397
ENST00000537841	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4420	1152	219	4322	1367
ENST00000537841	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5310	1152	219	4322	1367
ENST00000537841	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5415	1152	219	4430	1403
ENST00000537841	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5523	1152	219	4535	1438
ENST00000537841	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4431	1152	219	4430	1403
ENST00000542729	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4300	1032	219	4202	1327
ENST00000542729	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5190	1032	219	4202	1327
ENST00000542729	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5295	1032	219	4310	1363
ENST00000542729	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5403	1032	219	4415	1398
ENST00000542729	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4311	1032	219	4310	1363
ENST00000442944	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4392	1124	263	4294	1343
ENST00000442944	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5282	1124	263	4294	1343
ENST00000442944	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5387	1124	263	4402	1379
ENST00000442944	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5495	1124	263	4507	1414
ENST00000442944	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4403	1124	263	4402	1380
ENST00000544387	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4180	912	120	4082	1320
ENST00000544387	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5070	912	120	4082	1320
ENST00000544387	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5175	912	120	4190	1356
ENST00000544387	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5283	912	120	4295	1391
ENST00000544387	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4191	912	120	4190	1356
ENST00000543090	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4191	923	104	4093	1329
ENST00000543090	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5081	923	104	4093	1329
ENST00000543090	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5186	923	104	4201	1365
ENST00000543090	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5294	923	104	4306	1400
ENST00000543090	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4202	923	104	4201	1366
ENST00000392841	HMBS	chr11	118963731	+	ENST00000405015	EHBP1	chr2	63053222	+	4239	971	110	4141	1343
ENST00000392841	HMBS	chr11	118963731	+	ENST00000431489	EHBP1	chr2	63053222	+	5129	971	110	4141	1343
ENST00000392841	HMBS	chr11	118963731	+	ENST00000354487	EHBP1	chr2	63053222	+	5234	971	110	4249	1379
ENST00000392841	HMBS	chr11	118963731	+	ENST00000263991	EHBP1	chr2	63053222	+	5342	971	110	4354	1414
ENST00000392841	HMBS	chr11	118963731	+	ENST00000405289	EHBP1	chr2	63053222	+	4250	971	110	4249	1380

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000278715	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.002601277	0.99739873
ENST00000278715	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000814727	0.99918526
ENST00000278715	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001113038	0.998887
ENST00000278715	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000901302	0.9990988
ENST00000278715	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.003724514	0.99627554
ENST00000537841	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.002888382	0.99711156
ENST00000537841	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.00095957	0.9990404
ENST00000537841	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001300957	0.99869907
ENST00000537841	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001054557	0.9989454
ENST00000537841	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.004154876	0.99584514
ENST00000542729	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.003168516	0.9968315
ENST00000542729	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000985557	0.9990144
ENST00000542729	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001338745	0.9986613
ENST00000542729	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001089052	0.9989109
ENST00000542729	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.004572963	0.995427
ENST00000442944	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.002849593	0.9971505
ENST00000442944	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000926097	0.99907386
ENST00000442944	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001263272	0.9987367
ENST00000442944	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001023593	0.99897647
ENST00000442944	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.004106431	0.9958936
ENST00000544387	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.002731603	0.99726844
ENST00000544387	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000801336	0.99919873
ENST00000544387	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001097969	0.99890196
ENST00000544387	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000892208	0.9991078
ENST00000544387	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.003934407	0.99606556
ENST00000543090	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.002458126	0.9975419
ENST00000543090	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000767072	0.9992329
ENST00000543090	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001048056	0.9989519
ENST00000543090	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000851686	0.99914825
ENST00000543090	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.003558327	0.99644166
ENST00000392841	ENST00000405015	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.003075873	0.9969241
ENST00000392841	ENST00000431489	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000903125	0.9990969
ENST00000392841	ENST00000354487	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.001214532	0.99878544
ENST00000392841	ENST00000263991	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.000989054	0.9990109
ENST00000392841	ENST00000405289	HMBS	chr11	118963521	+	EHBP1	chr2	63053222	+	0.004378606	0.9956214
ENST00000278715	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.002712277	0.99728775
ENST00000278715	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000864061	0.9991359
ENST00000278715	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.00117009	0.9988299
ENST00000278715	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000943082	0.9990569
ENST00000278715	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.003866837	0.9961332
ENST00000537841	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.003018792	0.9969812
ENST00000537841	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001013063	0.9989869
ENST00000537841	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001365991	0.99863404
ENST00000537841	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001100558	0.99889946
ENST00000537841	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.004300003	0.9957
ENST00000542729	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.003283997	0.996716
ENST00000542729	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001035978	0.9989641
ENST00000542729	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001404739	0.9985953
ENST00000542729	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001135291	0.99886477
ENST00000542729	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.004706018	0.9952939
ENST00000442944	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.002988204	0.9970118
ENST00000442944	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000985916	0.999014
ENST00000442944	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.00132826	0.99867177
ENST00000442944	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001071599	0.99892837
ENST00000442944	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.004250248	0.9957497
ENST00000544387	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.002830288	0.9971697
ENST00000544387	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000844865	0.99915516
ENST00000544387	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001153964	0.99884605
ENST00000544387	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000931474	0.99906856
ENST00000544387	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.00406638	0.9959336
ENST00000543090	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.00256568	0.9974343
ENST00000543090	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000811817	0.9991881
ENST00000543090	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001096829	0.99890316
ENST00000543090	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.00088942	0.9991105
ENST00000543090	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.003686748	0.9963133
ENST00000392841	ENST00000405015	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.003203106	0.9967969
ENST00000392841	ENST00000431489	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.000959	0.999041
ENST00000392841	ENST00000354487	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001276454	0.99872357
ENST00000392841	ENST00000263991	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.001036414	0.9989636
ENST00000392841	ENST00000405289	HMBS	chr11	118963731	+	EHBP1	chr2	63053222	+	0.004518501	0.9954815

Top

Fusion Genomic Features for HMBS-EHBP1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
HMBS	chr11	118963731	+	EHBP1	chr2	63053221	+	0.01282122	0.9871788
HMBS	chr11	118963521	+	EHBP1	chr2	63053221	+	0.0055383	0.9944617
HMBS	chr11	118963731	+	EHBP1	chr2	63053221	+	0.01282122	0.9871788
HMBS	chr11	118963521	+	EHBP1	chr2	63053221	+	0.0055383	0.9944617

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for HMBS-EHBP1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:118963521/chr2:63053222)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

1076_1100

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

1136_1230

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

185_210

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

808_879

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

1076_1100

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

1136_1230

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

185_210

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

808_879

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

1076_1100

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

1136_1230

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

185_210

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

808_879

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

1076_1100

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

1136_1230

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

185_210

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

808_879

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

1076_1100

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

1136_1230

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

185_210

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

808_879

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

1076_1100

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

1136_1230

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

185_210

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

808_879

104

1232.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

1076_1100

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

1136_1230

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

185_210

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

808_879

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

1076_1100

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

1136_1230

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

185_210

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

808_879

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

1076_1100

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

1136_1230

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

185_210

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

808_879

104

1197.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

1076_1100

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

1136_1230

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

185_210

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

808_879

104

1161.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

1110_1113

104

1232.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

362_365

104

1232.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

1110_1113

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

362_365

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

1110_1113

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

362_365

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

1110_1113

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

362_365

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

1110_1113

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

362_365

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

1110_1113

104

1232.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

362_365

104

1232.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

1110_1113

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

362_365

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

1110_1113

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

362_365

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

1110_1113

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

362_365

104

1197.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

1110_1113

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

362_365

104

1161.0

Compositional bias

Note=Poly-Glu

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

1056_1212

104

1232.0

Domain

bMERB

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

443_548

104

1232.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

1056_1212

104

1197.0

Domain

bMERB

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

443_548

104

1197.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

1056_1212

104

1161.0

Domain

bMERB

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

443_548

104

1161.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

1056_1212

104

1197.0

Domain

bMERB

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

443_548

104

1197.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

1056_1212

104

1161.0

Domain

bMERB

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

443_548

104

1161.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

1056_1212

104

1232.0

Domain

bMERB

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

443_548

104

1232.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

1056_1212

104

1197.0

Domain

bMERB

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

443_548

104

1197.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

1056_1212

104

1161.0

Domain

bMERB

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

443_548

104

1161.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

1056_1212

104

1197.0

Domain

bMERB

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

443_548

104

1197.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

1056_1212

104

1161.0

Domain

bMERB

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

443_548

104

1161.0

Domain

Calponin-homology (CH)

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

1228_1231

104

1232.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

1228_1231

104

1197.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

1228_1231

104

1161.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

1228_1231

104

1197.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

1228_1231

104

1161.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

1228_1231

104

1232.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

1228_1231

104

1197.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

1228_1231

104

1161.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

1228_1231

104

1197.0

Motif

CAAX motif

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

1228_1231

104

1161.0

Motif

CAAX motif

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000263991

8_158

104

1232.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000354487

8_158

104

1197.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405015

8_158

104

1161.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000405289

8_158

104

1197.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963521

chr2:63053222

ENST00000431489

8_158

104

1161.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000263991

8_158

104

1232.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000354487

8_158

104

1197.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405015

8_158

104

1161.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000405289

8_158

104

1197.0

Domain

C2 NT-type

Tgene

EHBP1

chr11:118963731

chr2:63053222

ENST00000431489

8_158

104

1161.0

Domain

C2 NT-type

Top

Fusion Gene Sequence for HMBS-EHBP1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>36771_36771_1_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5347nt_BP=976nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGG
TCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAA
GCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACAT
GCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAA
CAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGA
CTGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGA
AAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACC
TATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTA
TTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGA
TATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCC
TCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACC
AAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTT
GGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTAC
TACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGA
TATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGC
AATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGA
AAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAG
TGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAG
CGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAG
TGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCA
AGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATAT
GTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAA
TTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAG
TAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGC
AGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAG
AAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGA
AGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGG
TGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCC
TGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTT
GAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCA
GGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGA
TTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGA
TACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGA
CACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCT
TCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTT
AATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAAT
GCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCG
CGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGG
CAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCA
AACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCAC
CACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGA
AATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTT
CCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGG
GGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATC
ATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCT
CTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTG
ATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCC
TACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAA
TCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATAT

>36771_36771_1_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1402AA_BP=274
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDF
EEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELN
PFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDES
NPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKN
YRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSG
QELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPST
ASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIG
SNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKE
RARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDN
IEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTER
FRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQID
TRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLL

--------------------------------------------------------------
>36771_36771_2_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5239nt_BP=976nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGG
TCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAA
GCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACAT
GCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAA
CAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCAC
CGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGC
TTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGA
TGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCT
CTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTT
GGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATT
AAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAA
TGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAA
TGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAA
CAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACT
GACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAG
CACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGA
GCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTC
AGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCA
GAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTT
AGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTAT
TTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGA
ATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCT
TGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAA
AATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTT
AAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCA
GCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGA
AAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGT
AGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCT
CCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGG
CACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAA
AACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAA
TGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGT
AGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGA
CACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAA
TCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGA
CTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAG
GGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAA
AGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCA
GACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCC
TCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAG
ATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCT
CTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAA
GAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTT
ATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCT
CAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTA
CAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGT
CTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATAT
TTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAA

>36771_36771_2_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1367AA_BP=274
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDF
EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEV
QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAP
PVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKS
LNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKF
YAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSN
TDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKL
GYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLS
DQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNS
KLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQR
SIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVN
KKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL

--------------------------------------------------------------
>36771_36771_3_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4244nt_BP=976nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGG
TCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAA
GCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACAT
GCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAA
CAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCAC
CGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGC
TTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGA
TGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCT
CTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTT
GGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATT
AAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAA
TGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAA
TGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAA
CAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACT
GACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAG
CACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGA
GCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTC
AGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCA
GAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTT
AGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTAT
TTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGA
ATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCT
TGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAA
AATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTT
AAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCA
GCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGA
AAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACA
GGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGAC
TGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTT
CAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGAT
AACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGC
ACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGA
AGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGA
AAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGC
CCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGA
GAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCT
TCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAA

>36771_36771_3_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1331AA_BP=274
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDF
EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEV
QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAP
PVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKS
LNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKF
YAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSN
TDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKL
GYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLS
DQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQD
MKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDT
SQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAML

--------------------------------------------------------------
>36771_36771_4_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4255nt_BP=976nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGG
TCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAA
GCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACAT
GCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAA
CAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCAC
CGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGC
TTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGA
TGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCT
CTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTT
GGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATT
AAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAA
TGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAA
TGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAA
CAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACT
GACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAG
CACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGA
GCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTC
AGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCA
GAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTT
AGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTAT
TTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGA
ATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCT
TGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAA
AATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTT
AAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCA
GCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGA
AAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGT
AGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCT
CCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGG
CACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAA
AACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAA
TGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGT
AGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGA
CACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAA
TCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGA
CTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAG
GGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAA

>36771_36771_4_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1368AA_BP=274
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDF
EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEV
QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAP
PVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKS
LNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKF
YAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSN
TDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKL
GYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLS
DQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNS
KLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQR
SIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVN
KKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL

--------------------------------------------------------------
>36771_36771_5_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5134nt_BP=976nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGG
TCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAA
GCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACAT
GCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAA
CAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCAC
CGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGC
TTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGA
TGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCT
CTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTT
GGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATT
AAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAA
TGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAA
TGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAA
CAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACT
GACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAG
CACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGA
GCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTC
AGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCA
GAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTT
AGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTAT
TTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGA
ATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCT
TGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAA
AATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTT
AAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCA
GCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGA
AAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACA
GGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGAC
TGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTT
CAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGAT
AACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGC
ACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGA
AGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGA
AAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGC
CCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGA
GAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCT
TCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAA
AACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATA
CAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTG
TGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAG
GAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTT
TTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATT
TACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAA
CATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCAT
CCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGA
ATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGC
ACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCT

>36771_36771_5_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000278715_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1331AA_BP=274
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDF
EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEV
QTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAP
PVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKS
LNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKF
YAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSN
TDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKL
GYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLS
DQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQD
MKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDT
SQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAML

--------------------------------------------------------------
>36771_36771_6_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5255nt_BP=884nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACT
GCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAA
AGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTA
TCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATT
TGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATA
TGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTC
CTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAA
AAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGG
GGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTA
CATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATA
TTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAA
TTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAA
ACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTG
ATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCG
GGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTG
ACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAG
CACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGT
CTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATT
CCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTA
GAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAG
ATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAA
GAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAG
AGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTG
AAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTG
AAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGA
AGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGG
ACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATT
CTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATA
CAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACA
CCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTC
GCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAA
TAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGC
TAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCG
ATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCA
AGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAA
CCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCA
CCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAA
TCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCC
CTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGG
TACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCAT
ATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCT
CCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGAT
ATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTA
CATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATC
CCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAA

>36771_36771_6_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1385AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASP
RKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVN
PVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGL
SFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTY
KVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKS
QQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECR
SDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKA
GNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGG
GDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQ
LQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTG
RNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL

--------------------------------------------------------------
>36771_36771_7_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5147nt_BP=884nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG
TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT
CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG
AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT
ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG
TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA
ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATG
CTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATG
GTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACA
AAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGA
CTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCA
CATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGC
CTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAG
AAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGA
AGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAG
GCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTT
GTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAAT
GCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTG
CTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAA
TAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAA
AGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGC
TGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAA
AGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAG
GAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCC
TAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCA
CAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAA
CTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATG
AGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAG
TAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACA
CAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATC
AGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACT
GGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGG
ACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAG
AGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGA
CTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTC
CTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGAT
TTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCT
CATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGA
AAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTAT
TAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCA
GAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACA
AAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCT
CAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTT
TCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGC

>36771_36771_7_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1350AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQV
ANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAIT
ETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEK
EHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKEEKCVLQ

--------------------------------------------------------------
>36771_36771_8_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4152nt_BP=884nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG
TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT
CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG
AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT
ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG
TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA
ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATG
CTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATG
GTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACA
AAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGA
CTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCA
CATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGC
CTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAG
AAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGA
AGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAG
GCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTT
GTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAAT
GCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTG
CTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAA
TAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAA
AGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGC
TGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAA
AGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGG
TGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTG
AACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCA
GCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAA
CTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCAC
TAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAG
AAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAA
AAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCC
AGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGA
AGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTC
AGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAA

>36771_36771_8_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1314AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTT
ERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQ
IDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQL

--------------------------------------------------------------
>36771_36771_9_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4163nt_BP=884nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG
TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT
CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG
AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT
ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG
TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA
ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATG
CTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATG
GTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACA
AAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGA
CTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCA
CATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGC
CTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAG
AAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGA
AGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAG
GCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTT
GTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAAT
GCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTG
CTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAA
TAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAA
AGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGC
TGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAA
AGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAG
GAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCC
TAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCA
CAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAA
CTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATG
AGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAG
TAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACA
CAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATC
AGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACT
GGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGG
ACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAG

>36771_36771_9_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1351AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQV
ANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAIT
ETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEK
EHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKEEKCVLQ

--------------------------------------------------------------
>36771_36771_10_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5042nt_BP=884nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG
TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT
CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG
AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT
ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG
TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA
ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATG
CTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATG
GTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACA
AAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGA
CTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCA
CATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGC
CTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAG
AAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGA
AGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAG
GCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTT
GTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAAT
GCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTG
CTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAA
TAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAA
AGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGC
TGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAA
AGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGG
TGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTG
AACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCA
GCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAA
CTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCAC
TAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAG
AAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAA
AAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCC
AGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGA
AGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTC
AGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAA
CTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACA
GAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTG
AGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGA
AAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTT
TCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTA
CCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACA
TAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCC
GAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAAT
GCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCAC
TGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCTTA

>36771_36771_10_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000392841_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1314AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTT
ERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQ
IDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQL

--------------------------------------------------------------
>36771_36771_11_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5408nt_BP=1037nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCA
TCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCG
CTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGA
AGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTA
AAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAG
CTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATC
CATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAA
CAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCAT
TTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTT
CTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTC
AAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAG
TTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTT
TGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTT
GTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACG
ATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTT
ATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTG
GAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAAC
AGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATC
AAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGA
GCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGAC
TATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAG
ATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATC
CAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAAC
ATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATC
GATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATA
AGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAG
CTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAA
GGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATG
AACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGC
CACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCC
GGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGT
CTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAG
CGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGG
CAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACA
CAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTC
TGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCG
AGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGC
AGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTG
TTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGAT
TTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAA
TATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACAC
CTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATG
AGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGA
TTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTC
TATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCT
TTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTA
TCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTC
ACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCA
TAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTT

>36771_36771_11_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1385AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASP
RKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVN
PVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGL
SFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTY
KVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKS
QQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECR
SDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKA
GNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGG
GDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQ
LQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTG
RNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL

--------------------------------------------------------------
>36771_36771_12_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5300nt_BP=1037nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCA
TCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCG
CTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGA
AGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTA
AAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTG
ATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTT
ATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGG
ATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAG
AAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTG
AAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAG
ATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTA
AAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACC
ACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCA
TAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAA
GGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAG
ATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAG
CAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATC
ACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTT
CAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGA
CTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTC
AAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCA
AAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGC
AGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGAC
AAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACA
CAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAG
CAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTG
GAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAG
AAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATT
CACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTAC
AAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATA
TTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTC
AGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATG
AGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAG
CTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATG
ATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGAC
GCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCG
AAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCAT
CAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACA
TTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAA
AATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGG
TATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAA
ACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCT
GCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAG
TTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAA
ACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACA
CCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAAT
ATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTT

>36771_36771_12_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1350AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQV
ANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAIT
ETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEK
EHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKEEKCVLQ

--------------------------------------------------------------
>36771_36771_13_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4305nt_BP=1037nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCA
TCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCG
CTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGA
AGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTA
AAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTG
ATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTT
ATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGG
ATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAG
AAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTG
AAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAG
ATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTA
AAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACC
ACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCA
TAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAA
GGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAG
ATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAG
CAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATC
ACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTT
CAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGA
CTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTC
AAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCA
AAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGC
AGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGAC
AAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACA
CAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAG
CAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTG
GAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCC
AGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTT
TTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGA
TGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAG
ATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACA
CCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGT
TTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATG
AGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAG
ATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATT
TGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTC

>36771_36771_13_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1314AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTT
ERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQ
IDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQL

--------------------------------------------------------------
>36771_36771_14_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4316nt_BP=1037nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCA
TCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCG
CTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGA
AGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTA
AAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTG
ATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTT
ATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGG
ATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAG
AAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTG
AAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAG
ATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTA
AAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACC
ACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCA
TAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAA
GGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAG
ATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAG
CAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATC
ACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTT
CAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGA
CTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTC
AAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCA
AAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGC
AGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGAC
AAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACA
CAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAG
CAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTG
GAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAG
AAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATT
CACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTAC
AAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATA
TTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTC
AGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATG
AGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAG
CTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATG
ATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGAC
GCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCG

>36771_36771_14_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1351AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQV
ANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAIT
ETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEK
EHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKEEKCVLQ

--------------------------------------------------------------
>36771_36771_15_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5195nt_BP=1037nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCA
TCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCG
CTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGA
AGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTA
AAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTG
ATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTT
ATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGG
ATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAG
AAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTG
AAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAG
ATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTA
AAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACC
ACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCA
TAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAA
GGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAG
ATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAG
CAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATC
ACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTT
CAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGA
CTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTC
AAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCA
AAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGC
AGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGAC
AAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACA
CAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAG
CAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTG
GAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCC
AGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTT
TTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGA
TGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAG
ATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACA
CCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGT
TTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATG
AGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAG
ATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATT
TGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTC
TCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTG
TACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGA
TTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGA
AACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTG
TTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTAC
TCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGC
GTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGA
AGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGAT
AATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATA
AAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGT

>36771_36771_15_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000442944_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1314AA_BP=257
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALAT
SSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEK
AAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVT
IKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSA
GKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGF
ASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPI
SGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLK
AETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHAS
LRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQ
LIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTT
ERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQ
IDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQL

--------------------------------------------------------------
>36771_36771_16_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5436nt_BP=1065nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGT
CGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAG
CCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATG
CAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAAC
AGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGAC
TGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAA
AAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCT
ATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTAT
TTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGAT
ATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCT
CCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCA
AAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTG
GGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACT
ACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGAT
ATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCA
ATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAA
AACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGT
GATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGC
GGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGT
GACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAA
GCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATG
TCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAAT
TCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGT
AGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCA
GATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGA
AGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAA
GAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGT
GAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCT
GAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTG
AAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAG
GACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGAT
TCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGAT
ACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGAC
ACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTT
CGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTA
ATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATG
CTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGC
GATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGC
AAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAA
ACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACC
ACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAA
ATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTC
CCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGG
GTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCA
TATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTC
TCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGA
TATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCT
ACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAAT
CCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATA

>36771_36771_16_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1409AA_BP=281
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQAD
IGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDD
PDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTE
EEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVW
CKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQ
IRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPD
DHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQK
LQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLS
RQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKA
SGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTER
LQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALE
NEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQK

--------------------------------------------------------------
>36771_36771_17_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5328nt_BP=1065nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGT
CGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAG
CCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATG
CAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAAC
AGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACC
GTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCT
TCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGAT
GAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTC
TATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTG
GTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTA
AATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAAT
GCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAAT
GGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAAC
AAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTG
ACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGC
ACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAG
CCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCA
GAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAG
AAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTA
GGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATT
TGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAA
TGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTT
GCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAA
ATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTA
AAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAG
CTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAA
AAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTA
GGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTC
CTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGC
ACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAA
ACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAAT
GAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTA
GTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGAC
ACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAAT
CAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGAC
TGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGG
GACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAA
GAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAG
ACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCT
CCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGA
TTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTC
TCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAG
AAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTA
TTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTC
AGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTAC
AAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTC
TCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATT
TTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAG

>36771_36771_17_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1374AA_BP=281
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQAD
IGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNS
YNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRV
KRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRP
DLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNS
SVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSD
DPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTS
LSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATP
FCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDL
DTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENR
PEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQ
EWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEED

--------------------------------------------------------------
>36771_36771_18_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4333nt_BP=1065nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGT
CGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAG
CCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATG
CAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAAC
AGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACC
GTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCT
TCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGAT
GAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTC
TATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTG
GTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTA
AATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAAT
GCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAAT
GGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAAC
AAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTG
ACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGC
ACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAG
CCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCA
GAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAG
AAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTA
GGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATT
TGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAA
TGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTT
GCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAA
ATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTA
AAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAG
CTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAA
AAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAG
GTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACT
GAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTC
AGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATA
ACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCA
CTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAA
GAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAA
AAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCC
CAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAG
AAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTT
CAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAA

>36771_36771_18_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1338AA_BP=281
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQAD
IGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNS
YNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRV
KRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRP
DLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNS
SVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSD
DPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTS
LSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATP
FCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAV
TESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVL
NKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLN

--------------------------------------------------------------
>36771_36771_19_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4344nt_BP=1065nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGT
CGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAG
CCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATG
CAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAAC
AGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACC
GTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCT
TCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGAT
GAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTC
TATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTG
GTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTA
AATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAAT
GCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAAT
GGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAAC
AAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTG
ACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGC
ACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAG
CCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCA
GAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAG
AAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTA
GGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATT
TGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAA
TGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTT
GCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAA
ATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTA
AAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAG
CTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAA
AAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTA
GGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTC
CTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGC
ACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAA
ACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAAT
GAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTA
GTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGAC
ACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAAT
CAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGAC
TGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGG
GACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAA

>36771_36771_19_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1374AA_BP=281
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQAD
IGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNS
YNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRV
KRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRP
DLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNS
SVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSD
DPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTS
LSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATP
FCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDL
DTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENR
PEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQ
EWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEED

--------------------------------------------------------------
>36771_36771_20_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5223nt_BP=1065nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGT
CGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAG
CCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATG
CAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAAC
AGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACC
GTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCT
TCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGAT
GAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTC
TATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTG
GTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTA
AATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAAT
GCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAAT
GGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAAC
AAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTG
ACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGC
ACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAG
CCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCA
GAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAG
AAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTA
GGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATT
TGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAA
TGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTT
GCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAA
ATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTA
AAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAG
CTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAA
AAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAG
GTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACT
GAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTC
AGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATA
ACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCA
CTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAA
GAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAA
AAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCC
CAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAG
AAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTT
CAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAA
ACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATAC
AGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGT
GAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGG
AAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTT
TTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTT
ACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAAC
ATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATC
CGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAA
TGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCA
CTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCTT

>36771_36771_20_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000537841_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1338AA_BP=281
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQAD
IGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNS
YNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRV
KRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRP
DLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNS
SVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSD
DPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTS
LSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATP
FCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAV
TESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVL
NKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLN

--------------------------------------------------------------
>36771_36771_21_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5316nt_BP=945nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATC
AATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCT
CTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAG
CAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAA
ATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCT
AAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCA
TTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACA
GAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTT
GTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCT
AAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAA
GAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTT
TCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTG
CTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGT
GCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGAT
GGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTAT
CTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGA
AACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAG
CCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAA
ACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGC
TCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTA
TTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGAT
GAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCA
GAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACAT
GCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGA
TTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAG
CACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCT
CGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGG
TCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAA
CTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCA
CAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGG
ACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCT
TTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCG
ATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCA
GCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACA
GAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTG
GAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAG
GCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAG
GAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTT
CTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTT
AAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATA
TACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCT
TGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAG
AGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATT
TTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTA
TTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTT
AACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATC
ATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCAC
GAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATA
GCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTAC

>36771_36771_21_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1369AA_BP=241
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQT
DVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSS
LDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFK
EVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAP
APPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDY
KSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQE
KFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGIC
SNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTS
KLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQ
LSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQ
NSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKR
QRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFML
VNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLER

--------------------------------------------------------------
>36771_36771_22_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5208nt_BP=945nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATC
AATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCT
CTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAG
CAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAA
ATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGAT
GCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTAT
AATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGAT
TCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAA
GAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAA
AGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGAT
CTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAA
GAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCAC
TTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATA
GGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGG
GCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGAT
ACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCA
GTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCAC
CTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCA
GGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACT
TTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAA
ACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAA
AAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAG
ACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAA
GAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACA
GCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCA
GAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGA
GATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAA
AATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCA
CCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAA
AAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATT
GAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAG
AGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAG
CAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCT
ATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGAT
TTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGC
GAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAA
GAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCA
GATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATT
TTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAA
TAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTA
TTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAAC
ATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGC
CACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTT
TTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAAC
AAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACC
ATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATAT
TTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTT

>36771_36771_22_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1334AA_BP=241
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQT
DVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDE
AEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRP
VDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP
VLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVL
LAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVN
DSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKK
DMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLN
HADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPS
YGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESS
EQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGF
KDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELR

--------------------------------------------------------------
>36771_36771_23_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4213nt_BP=945nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATC
AATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCT
CTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAG
CAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAA
ATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGAT
GCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTAT
AATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGAT
TCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAA
GAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAA
AGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGAT
CTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAA
GAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCAC
TTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATA
GGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGG
GCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGAT
ACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCA
GTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCAC
CTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCA
GGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACT
TTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAA
ACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAA
AAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAG
ACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAA
GAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACA
GCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCA
GAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGA
GAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAG
AAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTT
AGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATG
AAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGAT
GAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACC
CGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTT
ATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAG
CTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGAT
GAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTG
GAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTC

>36771_36771_23_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1298AA_BP=241
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQT
DVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDE
AEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRP
VDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP
VLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVL
LAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVN
DSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKK
DMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLN
HADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPS
YGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVR
KTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLM
DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALV

--------------------------------------------------------------
>36771_36771_24_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4224nt_BP=945nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATC
AATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCT
CTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAG
CAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAA
ATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGAT
GCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTAT
AATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGAT
TCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAA
GAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAA
AGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGAT
CTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAA
GAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCAC
TTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATA
GGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGG
GCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGAT
ACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCA
GTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCAC
CTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCA
GGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACT
TTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAA
ACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAA
AAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAG
ACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAA
GAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACA
GCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCA
GAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGA
GATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAA
AATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCA
CCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAA
AAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATT
GAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAG
AGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAG
CAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCT
ATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGAT
TTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGC
GAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAA

>36771_36771_24_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1334AA_BP=241
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQT
DVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDE
AEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRP
VDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP
VLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVL
LAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVN
DSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKK
DMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLN
HADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPS
YGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESS
EQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGF
KDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELR

--------------------------------------------------------------
>36771_36771_25_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5103nt_BP=945nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATC
AATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCT
CTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAG
CAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAA
ATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGAT
GCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTAT
AATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGAT
TCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAA
GAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAA
AGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGAT
CTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAA
GAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCAC
TTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATA
GGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGG
GCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGAT
ACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCA
GTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCAC
CTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCA
GGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACT
TTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAA
ACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAA
AAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAG
ACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAA
GAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACA
GCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCA
GAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGA
GAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAG
AAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTT
AGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATG
AAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGAT
GAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACC
CGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTT
ATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAG
CTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGAT
GAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTG
GAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTC
CCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTA
CTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATT
TTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAA
CTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTT
GGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTC
TGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGT
TTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAG
GTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAA
TTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAA
AAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTT

>36771_36771_25_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000542729_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1298AA_BP=241
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQT
DVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDE
AEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRP
VDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSP
VLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVL
LAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVN
DSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKK
DMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLN
HADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPS
YGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVR
KTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLM
DTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALV

--------------------------------------------------------------
>36771_36771_26_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5207nt_BP=836nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAA
GCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTT
GCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATT
TAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACC
AGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTG
AAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTG
CAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATA
ACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTC
CTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAAT
TGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGC
GAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCT
CTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAG
TTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTA
GACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAA
TTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCAC
ATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAA
ACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAG
ACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTA
GTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGAT
CTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAG
AATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTC
TAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAA
CAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGG
AGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAG
AACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCA
CCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAG
CTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATG
AAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATG
ACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCT
CCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAA
CAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGA
ATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGA
AGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAA
AGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGA
TGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAG
AACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAAC
AGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAG
AAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATC
AGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGT
TTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGC
TTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGG
AGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTA
TTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACA
TGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTC
TGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGC
CCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCT
TTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTAT
TCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGA

>36771_36771_26_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1371AA_BP=243
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPT
QTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNAL
SSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNP
FKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRK
APAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLI
DYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVD
QEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPG
ICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSP
TSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCN
RQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTP
EQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEM
KRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWF
MLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHL

--------------------------------------------------------------
>36771_36771_27_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5099nt_BP=836nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAA
GCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTT
GCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATT
TAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACA
AACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCAT
TTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCT
TTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAA
AAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATC
CTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGG
CCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGC
CAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACC
GAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTG
ACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGG
AACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAG
AACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATC
AAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGG
ATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCT
CCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAA
TATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTAT
ATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTA
ACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTA
CTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATG
CTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAG
CAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACA
GGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGA
AGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTG
AGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCG
AACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGA
AAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTA
GAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGA
AAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATG
AAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCC
GTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTA
TGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGC
TGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATG
AGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGG
AGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCC
CAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTAC
TACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTT
TTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAAC
TGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTG
GTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCT
GTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTT
TCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGG
TGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAAT
TATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAA
AGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTA

>36771_36771_27_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1336AA_BP=243
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPT
QTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFL
DEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNI
RPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIP
SPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDM
VLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVF
VNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDK
KKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTT
LNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSEL
PSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTE
SSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNK
GFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRE

--------------------------------------------------------------
>36771_36771_28_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4104nt_BP=836nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAA
GCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTT
GCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATT
TAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACA
AACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCAT
TTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCT
TTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAA
AAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATC
CTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGG
CCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGC
CAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACC
GAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTG
ACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGG
AACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAG
AACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATC
AAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGG
ATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCT
CCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAA
TATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTAT
ATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTA
ACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTA
CTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATG
CTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAG
CAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACA
GGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGA
AGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGG
TGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCT
CAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCA
GCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATAC
AGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGT
TCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGA
AGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAA
ATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGA
GGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGA
ACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAA
ACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTG

>36771_36771_28_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1300AA_BP=243
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPT
QTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFL
DEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNI
RPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIP
SPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDM
VLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVF
VNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDK
KKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTT
LNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSEL
PSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDST
VRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRY
LMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDA

--------------------------------------------------------------
>36771_36771_29_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4115nt_BP=836nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAA
GCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTT
GCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATT
TAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACA
AACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCAT
TTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCT
TTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAA
AAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATC
CTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGG
CCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGC
CAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACC
GAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTG
ACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGG
AACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAG
AACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATC
AAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGG
ATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCT
CCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAA
TATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTAT
ATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTA
ACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTA
CTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATG
CTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAG
CAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACA
GGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGA
AGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTG
AGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCG
AACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGA
AAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTA
GAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGA
AAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATG
AAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCC
GTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTA
TGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGC
TGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATG
AGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGG

>36771_36771_29_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1337AA_BP=243
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPT
QTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFL
DEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNI
RPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIP
SPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDM
VLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVF
VNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDK
KKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTT
LNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSEL
PSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTE
SSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNK
GFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRE

--------------------------------------------------------------
>36771_36771_30_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=4994nt_BP=836nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAA
GCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTT
GCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATT
TAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACA
AACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCAT
TTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCT
TTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAA
AAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATC
CTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGG
CCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGC
CAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACC
GAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTG
ACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGG
AACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAG
AACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATC
AAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGG
ATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCT
CCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAA
TATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTAT
ATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTA
ACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTA
CTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATG
CTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAG
CAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACA
GGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGA
AGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGG
TGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCT
CAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCA
GCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATAC
AGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGT
TCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGA
AGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAA
ATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGA
GGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGA
ACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAA
ACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTG
CTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTA
CCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATT
TCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAA
AACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAG
TGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAG
TTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGG
AGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGA
CTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCT
TGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTAC
AAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGT

>36771_36771_30_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000543090_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1300AA_BP=243
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPT
QTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFL
DEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNI
RPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIP
SPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDM
VLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVF
VNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDK
KKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTT
LNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSEL
PSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDST
VRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRY
LMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDA

--------------------------------------------------------------
>36771_36771_31_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5196nt_BP=825nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCA
ACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTG
AGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTC
GAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCT
CTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATC
AACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAAT
CCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAAT
CCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCT
ACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCA
AATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGA
AAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCT
AAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAAC
TACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTA
ATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTA
TTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGC
CAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTT
GATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCA
CAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACA
GCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCT
GGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGAC
TTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGT
AGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCT
CCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCA
GATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAA
AGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGC
AACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGA
GTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAAT
ATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACT
CCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCC
CAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGT
TTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAG
ATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAA
GATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGAC
ACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGG
TTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTAT
GAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTA
GATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCAT
TTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCT
CTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATT
GTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGG
ATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAG
AAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTT
GTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTA
CTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTG
CGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTG
AAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGA
TAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGAT
AAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATG

>36771_36771_31_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1362AA_BP=234
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFK
PLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDD
CIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQY
LNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSP
KTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQD
IKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELS
DLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQ
AQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYS
RDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDE
ERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDL
KLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQED
TKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNAL
IRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKG

--------------------------------------------------------------
>36771_36771_32_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5088nt_BP=825nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCA
ACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTG
AGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTC
GAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTT
TTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCT
GACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTG
CAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAAT
ATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAA
CCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCA
CCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATA
CCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAA
ATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCT
CTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGAT
ATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTC
GTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTC
TATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTA
TTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGT
CGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAAT
ACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGAT
AAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAA
GAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTT
GGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACC
ACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTG
CTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGT
GATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAA
CTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACT
AACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGT
AAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACT
GAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTT
GTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGA
TCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAAT
AAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTG
GTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAAT
AAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGG
GAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCC
CTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTG
GAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAG
AGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTC
TACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTT
AACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAA
GAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATA
ATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAAT
TTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGG
ATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAG
GATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACA
TCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTG
CCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAAT

>36771_36771_32_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1327AA_BP=234
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFK
PLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLAT
VNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYL
YADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPN
ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKL
TVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGES
ESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFI
CEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSK
IVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAE
KLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG
TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYV
VGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED

--------------------------------------------------------------
>36771_36771_33_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4093nt_BP=825nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCA
ACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTG
AGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTC
GAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTT
TTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCT
GACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTG
CAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAAT
ATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAA
CCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCA
CCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATA
CCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAA
ATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCT
CTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGAT
ATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTC
GTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTC
TATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTA
TTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGT
CGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAAT
ACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGAT
AAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAA
GAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTT
GGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACC
ACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTG
CTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGT
GATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAA
CTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAG
CTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGAC
ATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCT
ACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACA
AAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACC
AGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGC
TATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATA
AGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTA
GCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGAT
GCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAG
ATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACC

>36771_36771_33_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1291AA_BP=234
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFK
PLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLAT
VNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYL
YADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPN
ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKL
TVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGES
ESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFI
CEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSK
IVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAE
KLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSF
SQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTE
EEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQE

--------------------------------------------------------------
>36771_36771_34_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4104nt_BP=825nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCA
ACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTG
AGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTC
GAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTT
TTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCT
GACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTG
CAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAAT
ATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAA
CCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCA
CCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATA
CCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAA
ATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCT
CTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGAT
ATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTC
GTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTC
TATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTA
TTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGT
CGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAAT
ACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGAT
AAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAA
GAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTT
GGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACC
ACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTG
CTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGT
GATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAA
CTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACT
AACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGT
AAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACT
GAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTT
GTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGA
TCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAAT
AAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTG
GTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAAT
AAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGG
GAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCC
CTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTG

>36771_36771_34_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1327AA_BP=234
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFK
PLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLAT
VNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYL
YADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPN
ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKL
TVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGES
ESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFI
CEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSK
IVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAE
KLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG
TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYV
VGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED

--------------------------------------------------------------
>36771_36771_35_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=4983nt_BP=825nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAAGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCA
ACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTG
AGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTC
GAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTT
TTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCT
GACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTG
CAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAAT
ATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAA
CCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCA
CCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATA
CCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAA
ATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCT
CTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGAT
ATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTC
GTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTC
TATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTA
TTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGT
CGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAAT
ACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGAT
AAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAA
GAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTT
GGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACC
ACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTG
CTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGT
GATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAA
CTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAG
CTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGAC
ATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCT
ACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACA
AAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACC
AGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGC
TATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATA
AGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTA
GCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGAT
GCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAG
ATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACC
AGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACC
CTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATC
CTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCT
CGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTA
CAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATAT
CCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCC
TCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATAT
GCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACA
TTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCC
CCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAAT

>36771_36771_35_HMBS-EHBP1_HMBS_chr11_118963521_ENST00000544387_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1291AA_BP=234
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFK
PLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLAT
VNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYL
YADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPN
ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKL
TVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGES
ESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFI
CEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSK
IVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAE
KLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSF
SQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTE
EEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQE

--------------------------------------------------------------
>36771_36771_36_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5434nt_BP=1063nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGG
AGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCG
AAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCC
ATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCA
AAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAG
AGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTG
CATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAA
GGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTAT
CACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTT
GAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATAT
GAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCC
TCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAA
AACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGG
GCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTAC
ATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATAT
TAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAAT
TCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAA
CAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGA
TCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGG
GGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGA
CACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGC
ACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTC
TCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTC
CAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAG
AGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGA
TCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAG
AGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGA
GCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGA
AATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGA
AGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAA
GCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGA
CATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTC
TACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATAC
AAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACAC
CAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCG
CTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAAT
AAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCT
AGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGA
TGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAA
GATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAAC
CAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCAC
CCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAAT
CCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCC
TCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGT
ACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATA
TCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTC
CTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATA
TGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTAC
ATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCC
CCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAA

>36771_36771_36_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1431AA_BP=303
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLR
EGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELIN
KLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQST
KRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPK
PSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLL
EPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQ
DDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDL
YVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPD
ADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGV
KMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQ
KAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSED
EVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYE

--------------------------------------------------------------
>36771_36771_37_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5326nt_BP=1063nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGG
AGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCG
AAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCC
ATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCA
AAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAG
AGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGT
GAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTC
ACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGA
GCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTA
TGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGT
AAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAA
TGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGC
TAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGG
TTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAA
AAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGAC
TGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCAC
ATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCC
TGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGA
AAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAA
GTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGG
CAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTG
TGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATG
CAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGC
TAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAAT
AGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAA
GGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCT
GAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAA
GTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGG
AGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCT
AGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCAC
AGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAAC
TCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGA
GGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGT
AGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACAC
AGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCA
GCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTG
GCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGA
CCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGA
GGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGAC
TCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCC
TTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATT
TGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTC
ATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAA
AAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATT
AAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAG
AGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAA
AGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTC
AACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTT
CTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCA

>36771_36771_37_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1396AA_BP=303
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLR
EGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPD
SEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEP
KSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKI
TNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVV
QIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCR
RTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKE
KLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLL
EQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTN
EEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVV
FSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALV
EKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVAL

--------------------------------------------------------------
>36771_36771_38_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4331nt_BP=1063nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGG
AGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCG
AAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCC
ATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCA
AAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAG
AGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGT
GAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTC
ACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGA
GCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTA
TGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGT
AAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAA
TGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGC
TAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGG
TTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAA
AAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGAC
TGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCAC
ATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCC
TGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGA
AAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAA
GTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGG
CAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTG
TGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATG
CAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGC
TAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAAT
AGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAA
GGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCT
GAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAA
GTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGT
GGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGA
ACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAG
CCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAAC
TGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACT
AGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGA
AGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAA
AGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCA
GAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAA
GCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCA
GTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAAC

>36771_36771_38_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1360AA_BP=303
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLR
EGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPD
SEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEP
KSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKI
TNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVV
QIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCR
RTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKE
KLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLL
EQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKL
KKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTK
KGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIR
RMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKM

--------------------------------------------------------------
>36771_36771_39_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4342nt_BP=1063nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGG
AGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCG
AAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCC
ATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCA
AAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAG
AGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGT
GAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTC
ACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGA
GCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTA
TGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGT
AAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAA
TGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGC
TAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGG
TTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAA
AAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGAC
TGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCAC
ATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCC
TGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGA
AAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAA
GTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGG
CAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTG
TGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATG
CAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGC
TAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAAT
AGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAA
GGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCT
GAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAA
GTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGG
AGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCT
AGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCAC
AGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAAC
TCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGA
GGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGT
AGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACAC
AGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCA
GCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTG
GCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGA
CCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGA

>36771_36771_39_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1397AA_BP=303
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLR
EGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPD
SEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEP
KSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKI
TNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVV
QIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCR
RTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKE
KLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLL
EQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTN
EEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVV
FSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALV
EKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVAL

--------------------------------------------------------------
>36771_36771_40_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5221nt_BP=1063nt
GTGACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCG
GCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAAC
GGCGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGC
AACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAA
GATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCT
GCCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGT
TGGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCA
TCTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAAC
AGCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTT
GGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGA
AAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGG
AGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCG
AAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCC
ATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCA
AAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAG
AGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGT
GAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTC
ACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGA
GCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTA
TGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGT
AAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAA
TGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGC
TAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGG
TTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAA
AAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGAC
TGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCAC
ATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCC
TGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGA
AAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAA
GTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGG
CAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTG
TGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATG
CAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGC
TAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAAT
AGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAA
GGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCT
GAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAA
GTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGT
GGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGA
ACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAG
CCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAAC
TGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACT
AGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGA
AGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAA
AGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCA
GAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAA
GCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCA
GTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAAC
TTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAG
AACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGA
GTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAA
AATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTT
CCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTAC
CAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACAT
AGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCG
AGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATG
CTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACT
GTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCTTAA

>36771_36771_40_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000278715_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1360AA_BP=303
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTA
MKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLR
EGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPD
SEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEP
KSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKI
TNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVV
QIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCR
RTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKE
KLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLL
EQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKL
KKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTK
KGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIR
RMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKM

--------------------------------------------------------------
>36771_36771_41_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5342nt_BP=971nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAG
GAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAA
GGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCAT
TATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAA
GTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAG
TGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCA
TAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGG
ACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCA
CTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGA
ACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGA
GCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTC
CAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAA
CAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGC
GAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACAT
CGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTA
AAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTC
CTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACA
GCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATC
TGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGG
TTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACA
CAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCAC
AGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTC
CACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCA
GATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAG
ATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATC
ATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAG
ATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGC
GACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAA
TGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAG
GCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGC
TGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACA
TGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTA
CAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAA
AGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCA
GTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCT
ATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAA
GGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAG
CCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATG
CGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGA
TGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCA
GAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCC
TTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCC
TGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTC
GTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTAC
AAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATC
CAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCT
CTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATG
CACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACAT
TTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCC
CATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATT

>36771_36771_41_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1414AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNS
NPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYAD
SSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQ
SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVM
TYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESE
HQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEE
TDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQ
HRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLK
ERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTED
LRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGE
LAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQK

--------------------------------------------------------------
>36771_36771_42_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5234nt_BP=971nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAG
GAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAA
GGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCAT
TATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAA
GTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAG
TGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGA
ATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCAC
CTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGC
CAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATG
CTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAA
ATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATG
AAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTA
GTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTT
TATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAA
AGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTG
TTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACAT
ATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTG
AACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAA
GTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGT
CTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCA
AAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTG
AGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCA
GATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTA
AGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAG
TCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGG
CGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGA
GAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGT
TGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAG
GTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAG
AAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAG
AAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTC
AACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGG
AGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAG
GAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAG
GAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGC
TCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGC
AGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACC
TGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGG
AGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTC
ATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTT
TCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTG
CACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCAT
TTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAA
ATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAA
ACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAG
GATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAG
ACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAA
CATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCT
TCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGA

>36771_36771_42_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1379AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTN
LENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQ
YIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE
EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQ

--------------------------------------------------------------
>36771_36771_43_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4239nt_BP=971nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAG
GAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAA
GGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCAT
TATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAA
GTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAG
TGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGA
ATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCAC
CTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGC
CAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATG
CTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAA
ATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATG
AAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTA
GTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTT
TATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAA
AGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTG
TTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACAT
ATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTG
AACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAA
GTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGT
CTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCA
AAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTG
AGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCA
GATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTA
AGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAG
TCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGG
CGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGA
GAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGT
TGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGG
CAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAAC
GATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCC
AATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTG
AAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAG
AGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAG
AAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAG
AACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGA
AGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGC
AGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGT
AGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTT

>36771_36771_43_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1343AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSA
AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPS
EDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR

--------------------------------------------------------------
>36771_36771_44_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4250nt_BP=971nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAG
GAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAA
GGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCAT
TATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAA
GTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAG
TGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGA
ATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCAC
CTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGC
CAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATG
CTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAA
ATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATG
AAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTA
GTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTT
TATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAA
AGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTG
TTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACAT
ATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTG
AACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAA
GTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGT
CTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCA
AAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTG
AGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCA
GATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTA
AGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAG
TCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGG
CGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGA
GAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGT
TGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAG
GTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAG
AAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAG
AAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTC
AACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGG
AGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAG
GAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAG
GAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGC
TCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGC
AGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACC
TGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGG

>36771_36771_44_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1380AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTN
LENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQ
YIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE
EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQ

--------------------------------------------------------------
>36771_36771_45_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5129nt_BP=971nt
AGTGTCCTGGTTACTGCAGCGGCAGCAACAGCAGGTCCTACTATCGCCTCCCTCTAGTCTCTGCTTCTCTGGATCCCTGAGGAGGGCAGA
AGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAA
CATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGA
TTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGC
CCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTG
GGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATC
TGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAG
CTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGG
GCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAA
GGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAG
GAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAA
GGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCAT
TATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAA
GTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAG
TGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGA
ATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCAC
CTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGC
CAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATG
CTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAA
ATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATG
AAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTA
GTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTT
TATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAA
AGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTG
TTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACAT
ATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTG
AACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAA
GTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGT
CTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCA
AAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTG
AGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCA
GATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTA
AGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAG
TCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGG
CGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGA
GAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGT
TGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGG
CAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAAC
GATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCC
AATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTG
AAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAG
AGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAG
AAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAG
AACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGA
AGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGC
AGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGT
AGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTT
TTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAA
CTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGT
GATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAA
TTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCC
GGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCA
GTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAG
CCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAG
AATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCT
GTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGT

>36771_36771_45_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000392841_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1343AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSA
AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPS
EDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR

--------------------------------------------------------------
>36771_36771_46_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5495nt_BP=1124nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATA
GCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCA
ATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTC
TTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGC
AGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAA
TTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTA
AATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCAT
TTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAG
AAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTG
TGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTA
AAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAG
AACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTT
CTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGC
TTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTG
CAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATG
GATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATC
TCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAA
ACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGC
CTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAA
CTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCT
CTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTAT
TGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATG
AACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAG
AATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATG
CTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGAT
TGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGC
ACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTC
GTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGT
CAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAAC
TTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCAC
AGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGA
CTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTT
TCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGA
TAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAG
CACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAG
AAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGG
AAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGG
CCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGG
AGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTC
TTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTA
AAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATAT
ACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTT
GTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGA
GGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTT
TTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTAT
TTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTA
ACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCA
TCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACG
AATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAG
CACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACC

>36771_36771_46_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1414AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNS
NPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYAD
SSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQ
SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVM
TYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESE
HQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEE
TDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQ
HRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLK
ERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTED
LRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGE
LAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQK

--------------------------------------------------------------
>36771_36771_47_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5387nt_BP=1124nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATA
GCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCA
ATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTC
TTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGC
AGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAA
TTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATG
CTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATA
ATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATT
CTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAG
AATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAA
GGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATC
TCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAG
AAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACT
TTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAG
GAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGG
CACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATA
CAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAG
TAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACC
TTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAG
GATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTT
TAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAA
CTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAA
AAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGA
CGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAG
AAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAG
CCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAG
AAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAG
ATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAA
ATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCAC
CCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAA
AAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTG
AGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGA
GGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGC
AAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTA
TGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATT
TAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCG
AACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAG
AAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAG
ATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTT
TGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAAT
AGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTAT
TGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACA
TTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCC
ACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTT
TTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACA
AGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCA
TCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATT
TATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTG

>36771_36771_47_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1379AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTN
LENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQ
YIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE
EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQ

--------------------------------------------------------------
>36771_36771_48_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4392nt_BP=1124nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATA
GCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCA
ATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTC
TTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGC
AGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAA
TTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATG
CTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATA
ATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATT
CTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAG
AATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAA
GGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATC
TCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAG
AAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACT
TTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAG
GAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGG
CACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATA
CAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAG
TAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACC
TTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAG
GATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTT
TAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAA
CTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAA
AAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGA
CGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAG
AAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAG
CCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAG
AAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAG
AACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGA
AAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTA
GAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGA
AAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATG
AAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCC
GTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTA
TGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGC
TGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATG
AGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGG
AGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCC

>36771_36771_48_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1343AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSA
AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPS
EDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR

--------------------------------------------------------------
>36771_36771_49_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4403nt_BP=1124nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATA
GCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCA
ATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTC
TTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGC
AGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAA
TTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATG
CTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATA
ATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATT
CTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAG
AATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAA
GGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATC
TCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAG
AAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACT
TTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAG
GAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGG
CACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATA
CAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAG
TAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACC
TTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAG
GATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTT
TAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAA
CTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAA
AAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGA
CGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAG
AAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAG
CCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAG
AAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAG
ATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAA
ATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCAC
CCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAA
AAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTG
AGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGA
GGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGC
AAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTA
TGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATT
TAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCG
AACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAG

>36771_36771_49_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1380AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTN
LENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQ
YIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEE
EAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQ

--------------------------------------------------------------
>36771_36771_50_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5282nt_BP=1124nt
CCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCT
TAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGTCATTCCAGAGCCCTGGA
CTAGGAGTAGGAAGATCTGAATTGTGGCCCCAACTCTCTTTCGGTTATTAGCTCTGTGACCCTAGGAAGAAAACAGCCCAAAGATGAGAG
TGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGC
AGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGG
AGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCA
TCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGA
AGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACC
TCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACA
ACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGG
ACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAG
GCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATA
GCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCA
ATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTC
TTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGC
AGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAA
TTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATG
CTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATA
ATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATT
CTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAG
AATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAA
GGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATC
TCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAG
AAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACT
TTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAG
GAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGG
CACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATA
CAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAG
TAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACC
TTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAG
GATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTT
TAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAA
CTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAA
AAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGA
CGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAG
AAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAG
CCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAG
AAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAG
AACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGA
AAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTA
GAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGA
AAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATG
AAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCC
GTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTA
TGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGC
TGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATG
AGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGG
AGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCC
CAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTAC
TACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTT
TTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAAC
TGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTG
GTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCT
GTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTT
TCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGG
TGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAAT
TATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAA
AGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTA

>36771_36771_50_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000442944_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1343AA_BP=286
MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPG
FTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG
WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDG
SDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE
TERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAIL
HHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYE
TDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGR
TSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESP
IKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNT
NTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSA
AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPS
EDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERR

--------------------------------------------------------------
>36771_36771_51_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5523nt_BP=1152nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGA
GGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGA
AGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCA
TTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAA
AGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGA
GTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGC
ATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAG
GACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATC
ACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTG
AACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATG
AGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCT
CCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAA
ACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGG
CGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACA
TCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATT
AAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATT
CCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAAC
AGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGAT
CTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGG
GTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGAC
ACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCA
CAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCT
CCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCC
AGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGA
GATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGAT
CATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGA
GATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAG
CGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAA
ATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAA
GGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAG
CTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGAC
ATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCT
ACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACA
AAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACC
AGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGC
TATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATA
AGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTA
GCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGAT
GCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAG
ATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACC
AGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACC
CTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATC
CTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCT
CGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTA
CAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATAT
CCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCC
TCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATAT
GCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACA
TTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCC
CCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAAT

>36771_36771_51_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1438AA_BP=310
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFS
LSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSAS
SSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIK
DSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGK
DLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFAS
IGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISG
AVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAE
TLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLR
QTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLI
AEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVAN
SPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITET
QRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEH

--------------------------------------------------------------
>36771_36771_52_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5415nt_BP=1152nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGA
GGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGA
AGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCA
TTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAA
AGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGA
GTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTG
AATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCA
CCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAG
CCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTAT
GCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTA
AATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAAT
GAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCT
AGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGT
TTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAA
AAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACT
GTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACA
TATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCT
GAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAA
AGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAG
TCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGC
AAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGT
GAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGC
AGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCT
AAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATA
GTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAG
GCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTG
AGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAG
TTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGA
GGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTA
GAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACA
GAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACT
CAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAG
GAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTA
GGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACA
GGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAG
CTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGG
CAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGAC
CTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAG
GAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACT
CATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCT
TTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTT
GCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCA
TTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAA
AATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTA
AACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGA
GGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAA
GACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCA
ACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTC
TTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAG

>36771_36771_52_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1403AA_BP=310
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFS
LSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAEL
NPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDE
SNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTK
NYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFS
GQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPS
TASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDI
GSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELK
ERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDEND
NIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTE
RFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI
DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLL

--------------------------------------------------------------
>36771_36771_53_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4420nt_BP=1152nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGA
GGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGA
AGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCA
TTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAA
AGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGA
GTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTG
AATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCA
CCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAG
CCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTAT
GCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTA
AATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAAT
GAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCT
AGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGT
TTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAA
AAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACT
GTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACA
TATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCT
GAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAA
AGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAG
TCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGC
AAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGT
GAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGC
AGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCT
AAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATA
GTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAG
GCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTG
AGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAG
TTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTG
GCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAA
CGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGC
CAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACT
GAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTA
GAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAA
GAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAA
GAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAG
AAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAG
CAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAG
TAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACT

>36771_36771_53_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1367AA_BP=310
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFS
LSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAEL
NPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDE
SNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTK
NYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFS
GQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPS
TASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDI
GSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELK
ERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNS
KLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQR
SIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVN
KKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL

--------------------------------------------------------------
>36771_36771_54_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4431nt_BP=1152nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGA
GGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGA
AGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCA
TTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAA
AGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGA
GTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTG
AATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCA
CCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAG
CCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTAT
GCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTA
AATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAAT
GAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCT
AGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGT
TTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAA
AAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACT
GTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACA
TATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCT
GAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAA
AGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAG
TCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGC
AAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGT
GAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGC
AGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCT
AAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATA
GTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAG
GCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTG
AGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAG
TTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGA
GGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTA
GAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACA
GAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACT
CAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAG
GAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTA
GGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACA
GGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAG
CTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGG
CAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGAC
CTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAG

>36771_36771_54_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1403AA_BP=310
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFS
LSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAEL
NPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDE
SNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTK
NYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFS
GQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPS
TASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDI
GSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELK
ERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDEND
NIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTE
RFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQI
DTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLL

--------------------------------------------------------------
>36771_36771_55_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5310nt_BP=1152nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGGGGCCTTG
GGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTGTGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAA
AGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGA
GGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGA
AGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCA
TTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAA
AGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGA
GTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTG
AATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCA
CCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAG
CCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTAT
GCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTA
AATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAAT
GAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCT
AGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGT
TTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAA
AAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACT
GTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACA
TATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCT
GAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAA
AGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAG
TCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGC
AAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGT
GAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGC
AGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCT
AAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATA
GTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAG
GCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTG
AGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAG
TTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTG
GCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAA
CGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGC
CAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACT
GAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTA
GAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAA
GAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAA
GAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAG
AAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAG
CAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAG
TAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACT
TTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGA
ACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAG
TGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAA
ATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTC
CGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACC
AGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATA
GCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGA
GAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGC
TGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTG
TCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCTTAAA

>36771_36771_55_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000537841_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1367AA_BP=310
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSV
PVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFS
LSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAEL
NPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDE
SNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTK
NYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFS
GQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPS
TASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDI
GSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELK
ERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNS
KLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQR
SIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVN
KKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTL

--------------------------------------------------------------
>36771_36771_56_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5403nt_BP=1032nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGC
ATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAA
TCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTT
GATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAA
GACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTG
ACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAA
ACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAA
CTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCT
GCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTT
GTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCA
ATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGA
TTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTC
TATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAAC
TATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCT
ATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACT
CCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCT
GGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTG
AAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAA
CAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAA
TCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCT
TCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTG
TTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCAC
AATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGT
CAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCA
AAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTT
ACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAG
GTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACT
GAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTC
AGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATA
ACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCA
CTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAA
GAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAA
AAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCC
CAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAG
AAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTT
CAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAA
ACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATAC
AGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGT
GAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGG
AAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTT
TTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTT
ACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAAC
ATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATC
CGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAA
TGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCA
CTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTTCAATAAAAGCAGAAACTTTCTTACCTT

>36771_36771_56_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1398AA_BP=270
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPA
QESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDN
EDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGD
PDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFY
EPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGV
KITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELN
VVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPY
CRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLE
KEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARV
LLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEID
TNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNP
VVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAA
LVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELV

--------------------------------------------------------------
>36771_36771_57_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5295nt_BP=1032nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGC
ATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT
GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT
AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT
CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA
TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG
CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC
TCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAA
GTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTT
AGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGA
ATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCA
CATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACA
AACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTA
GACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTT
AGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGA
TCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTA
GAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACT
CTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAA
ACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACG
GAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAA
GAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCC
ACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAA
GCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAT
GAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAAT
GACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCC
TCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAA
ACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAG
AATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGG
AAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAA
AAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATG
ATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTA
GAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAA
CAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAA
GAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGAT
CAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTG
TTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAG
CTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTG
GAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATT
ATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCAC
ATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTT
CTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAG
CCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATC
TTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTA
TTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTG

>36771_36771_57_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1363AA_BP=270
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPA
QESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDN
EDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQ
YLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLS
PKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQ
DIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAEL
SDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDST
QAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSY
SRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQD
EERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVD
LKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQE
DTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNA
LIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNK

--------------------------------------------------------------
>36771_36771_58_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4300nt_BP=1032nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGC
ATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT
GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT
AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT
CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA
TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG
CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC
TCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAA
GTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTT
AGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGA
ATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCA
CATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACA
AACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTA
GACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTT
AGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGA
TCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTA
GAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACT
CTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAA
ACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACG
GAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAA
GAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCC
ACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAA
GCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAA
CAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAA
GCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGA
AATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAA
AGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAA
GTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGT
GCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATG
TTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTG
CTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAG
CTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAG
CGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCA

>36771_36771_58_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1327AA_BP=270
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPA
QESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDN
EDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQ
YLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLS
PKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQ
DIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAEL
SDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDST
QAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSY
SRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQD
EERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG
TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYV
VGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED

--------------------------------------------------------------
>36771_36771_59_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4311nt_BP=1032nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGC
ATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT
GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT
AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT
CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA
TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG
CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC
TCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAA
GTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTT
AGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGA
ATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCA
CATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACA
AACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTA
GACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTT
AGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGA
TCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTA
GAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACT
CTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAA
ACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACG
GAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAA
GAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCC
ACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAA
GCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAT
GAAAATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAAT
GACCTTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCC
TCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAA
ACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAG
AATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGG
AAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAA
AAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATG
ATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTA
GAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAA
CAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAA

>36771_36771_59_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1363AA_BP=270
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPA
QESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDN
EDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQ
YLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLS
PKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQ
DIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAEL
SDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDST
QAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSY
SRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQD
EERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVD
LKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQE
DTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNA
LIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNK

--------------------------------------------------------------
>36771_36771_60_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5190nt_BP=1032nt
GACGCGAGGCTCTGCGGAGACCAGGAGTCAGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGC
TTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGG
CGGTGAGTGCTGAGCCGGTGACCAGCACACTTTGGGCTTCTGGACGAGCCGTGCAGCGATTGGCCCCAGGTTGCCATCCTCAGTCGTCTA
TTGGAAGAAAACAGCCCAAAGATGAGAGTGATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCA
ACATTGAAAGCCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAG
ATTGGAGAGAAAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTG
CCCACTGTGCTTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTT
GGGAAGACCCTAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCAT
CTGGAGTTCAGGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACA
GCTGGCCTGCAGCGCATGGGCTGGCACAACCGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGC
TGCAGTGTGCCAGTAGCCGTGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGC
ATACAAGAGACCATGCAGGCTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT
GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT
AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT
CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA
TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG
CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC
TCTACTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAA
GTTACAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTT
AGACCAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGA
ATTTCCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCA
CATTTCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACA
AACAGTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTA
GACTTCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTT
AGTCCAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGA
TCTGATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTA
GAATTGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACT
CTAGACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAA
ACAAGTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACG
GAGTCTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAA
GAACTTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCC
ACCCCATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAA
GCTCGATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAA
CAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAA
GCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGA
AATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAA
AGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAA
GTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGT
GCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATG
TTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTG
CTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAG
CTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAG
CGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCA
ACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTA
CTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTT
TTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTG
TTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGT
AATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGT
TACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTC
ACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTG
AGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTA
TTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAG
TCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATT

>36771_36771_60_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000542729_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1327AA_BP=270
MDEPCSDWPQVAILSRLLEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEH
ALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTR
LRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPA
QESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDN
EDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQ
YLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLS
PKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQ
DIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAEL
SDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDST
QAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSY
SRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQD
EERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSG
TEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYV
VGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIED

--------------------------------------------------------------
>36771_36771_61_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5294nt_BP=923nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGG
CTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCC
CTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCA
TTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAG
ATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGT
TGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAG
AGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAG
AATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACA
GCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTC
CCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGG
ATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAG
TGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTA
CTTCTCCTAAGCCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTA
CAAAGAACTACCGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGAC
CAGATTTAATTGACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTT
CCCGATTATTGGAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATT
TCAGTGGCCAAGAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACA
GTTCTGTTGATCAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACT
TCTTATCACAGGATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTC
CAAGCACAGCCTCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTG
ATGACCCTGGAATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAAT
TGAGTGACTTATATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAG
ACATCGGTAGTAACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAA
GTTTATCTCCTACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGT
CTGATCCAGATGCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAAC
TTAAGGAAAGAGCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCC
CATTCTGCAACAGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTC
GATCTGGAGTGAAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAA
ATGATAATATTGAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACC
TTGATACTCCCGAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCA
GTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAA
CAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATA
GACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGC
CATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGC
AAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGC
AGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAAC
GACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGC
TTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAG
ATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGA
AAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTG
GCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTC
ATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGG
TGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTC
TTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGT
AACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGC
AGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCT
GTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTT
TCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCT
GTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAA

>36771_36771_61_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1400AA_BP=272
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHV
PAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEE
DNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPF
GDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNP
FYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYR
GVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQE
LNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTAS
PYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSN
LEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERA
RVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIE
IDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFR
NPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTR
AALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDE

--------------------------------------------------------------
>36771_36771_62_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5186nt_BP=923nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGG
CTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCC
CTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCA
TTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAG
ATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAAC
TTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTG
GAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTA
AAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAA
GAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTT
TTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCC
CGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAA
GCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAG
GAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACT
ACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAAC
CTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAAC
TAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAG
AAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATG
ACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCC
CTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATAT
GTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATG
TTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACT
TGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTT
CTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTG
ATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAA
GAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGC
AGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGA
TGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGA
TAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAAC
AAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAG
CTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAA
ATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAA
GGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAG
TGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTG
CCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGT
TAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGC
TGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGC
TGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGC
GAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAA
CATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTAC
TTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTT
TGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGT
TCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTA
ATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTT
ACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCA
CTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGA
GCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTAT
TTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGT
CTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTT

>36771_36771_62_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1365AA_BP=272
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHV
PAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEE
DNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQT
PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPV
LSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLN
PQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYA
ELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTD
STQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGY
SYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQ
QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKL
VDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSI
QEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKK
NALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQ

--------------------------------------------------------------
>36771_36771_63_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4191nt_BP=923nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGG
CTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCC
CTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCA
TTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAG
ATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAAC
TTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTG
GAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTA
AAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAA
GAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTT
TTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCC
CGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAA
GCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAG
GAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACT
ACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAAC
CTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAAC
TAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAG
AAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATG
ACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCC
CTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATAT
GTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATG
TTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACT
TGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTT
CTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTG
ATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAA
GAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGC
AGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGA
TGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGG
ACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAG
AGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCA
AAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGG
AAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCA
AAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGC
GCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATG
CCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGG
CAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACA
AGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACA
AAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTT

>36771_36771_63_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1329AA_BP=272
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHV
PAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEE
DNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQT
PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPV
LSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLN
PQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYA
ELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTD
STQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGY
SYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQ
QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMK
SGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQ
YVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAI

--------------------------------------------------------------
>36771_36771_64_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4202nt_BP=923nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGG
CTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCC
CTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCA
TTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAG
ATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAAC
TTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTG
GAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTA
AAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAA
GAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTT
TTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCC
CGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAA
GCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAG
GAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACT
ACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAAC
CTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAAC
TAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAG
AAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATG
ACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCC
CTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATAT
GTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATG
TTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACT
TGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTT
CTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTG
ATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAA
GAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGC
AGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGA
TGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGA
TAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAAC
AAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAG
CTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAA
ATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAA
GGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAG
TGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTG
CCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGT
TAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGC
TGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGC
TGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGC

>36771_36771_64_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1366AA_BP=272
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHV
PAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEE
DNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQT
PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPV
LSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLN
PQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYA
ELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTD
STQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGY
SYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQ
QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKL
VDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSI
QEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKK
NALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQ

--------------------------------------------------------------
>36771_36771_65_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5081nt_BP=923nt
TCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCACCCACACACAGCCTACT
TTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAG
CCTCGTACCCTGGCCTGCAGTTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGA
AAAGCCTGTTTACCAAGGAGCTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGC
TTCCTCCTGGCTTCACCATCGGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCC
TAGAAACCCTGCCAGAGAAGAGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCA
GGAGTATTCGGGGAAACCTCAACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGC
AGCGCATGGGCTGGCACAACCGGGTGGGGCAGGGGGCCTTGGGCGTGGAAGTGCGAGCCAAGGACCAGGACATCTTGGATCTGGTGGGTG
TGCTGCACGATCCCGAGACTCTGCTTCGCTGCATCGCTGAAAGGGCCTTCCTGAGGCACCTGGAAGGAGGCTGCAGTGTGCCAGTAGCCG
TGCATACAGCTATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGG
CTACCATCCATGTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCC
CTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCA
TTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAG
ATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAAC
TTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTG
GAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTA
AAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAA
GAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTT
TTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCC
CGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAA
GCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAG
GAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACT
ACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAAC
CTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAAC
TAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAG
AAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATG
ACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCC
CTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATAT
GTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATG
TTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACT
TGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTT
CTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTG
ATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAA
GAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGC
AGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGA
TGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGG
ACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAG
AGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCA
AAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGG
AAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCA
AAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGC
GCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATG
CCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGG
CAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACA
AGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACA
AAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTT
CCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCA
CCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCC
TTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAAC
ACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGG
GAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTA
GATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGT
TCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTA
ATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGA
TTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAG
TAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCAT

>36771_36771_65_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000543090_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1329AA_BP=272
MSGNGNAAATALARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGF
TIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGW
HNRVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHV
PAQESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEE
DNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQT
PQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPV
LSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLN
PQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYA
ELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTD
STQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGY
SYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQ
QDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMK
SGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQ
YVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAI

--------------------------------------------------------------
>36771_36771_66_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000263991_length(transcript)=5283nt_BP=912nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCAT
GTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACT
CAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGG
GAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAA
GAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTG
AGCAGCTTAGATGAAGATCAAGATGACTGCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAAC
AAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCA
TTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCC
TTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACA
AAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAAT
CCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAG
GCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAG
CCAAGCCCTATACCAAGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTAC
CGAGGAGTAAAAATCACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATT
GACTACAAGTCTCTGAATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTG
GAACCTTCTGATATGGTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAA
GAACTAAATGTCGTTCAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGAT
CAAGAAAAATTCTATGCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAG
GATGACTCTGTATTTGTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCC
TCCCCTTACTGTCGCAGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGA
ATATGTTCCAATACAGATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTA
TATGTTAGTGATAAGAAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGT
AACTTGGAGAAAGAAAAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCT
ACTTCTAAACTTGGATACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGAT
GCTGATAGAACCACTTTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGA
GCAAGAGTTCTGCTTGAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAAC
AGGCAGCTAAGTGATCAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTG
AAGATGTCAGAACTTCCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATT
GAGATAGATACTAACGAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCC
GAACAAAACAGTAAGTTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAG
AAAGCTGTAACTGAGAGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTT
AGAAATCCTGTTGTGTTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATG
AAAAGGCAGAGATCAATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGAT
GAAGTGCTTAATAAAGGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACC
CGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTT
ATGTTAGTTAATAAGAAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAG
CTGCTGAACCGGGAATTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGAT
GAGCTGGTGGCCCTGGTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTG
GAGCGAACTCTGGAGCAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTC
CCAACATTTTAGAGTCTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTA
CTACTTTACCTCTACTTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATT
TTTTTGTGAGTTAACAATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAA
CTGTTCGAAAAAGAACAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTT
GGTAATAGCATAATGACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTC
TGTTACCTAAATTTTATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGT
TTCACTGTAAGGATAATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAG
GTGAGCTGTGAGGATGGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAA
TTATTTCTTACATCATGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAA
AAGTCTGTCTTGCCACTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTT

>36771_36771_66_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000263991_length(amino acids)=1391AA_BP=263
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGR
RKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENR
VNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPI
TETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPP
PNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTT
SWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEEN
SSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREPELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSD
TEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLGKKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENS
RSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLAKKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARR
DAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQLRERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPE
GFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDS
TVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLR
YLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRD

--------------------------------------------------------------
>36771_36771_67_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000354487_length(transcript)=5175nt_BP=912nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCAT
GTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACT
CAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGG
GAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAA
GAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTG
GATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGAC
TCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAG
ACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATA
AGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCT
AAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCA
GTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCA
AGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATC
ACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTG
AATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATG
GTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTT
CAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTAT
GCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTT
GTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGC
AGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACA
GATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAG
AAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAA
AAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGA
TACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACT
TTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTT
GAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGAT
CAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTT
CCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAAC
GAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAG
TTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAG
AGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTG
TTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCA
ATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAA
GGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTG
GAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAG
AAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAA
TTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTG
GTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAG
CAAAACAAAGGCAAGATGGCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGT
CTTGCTTCCCAAACCAGAAAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTAC
TTTACCACCACCACCCTTTTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAAC
AATTTCCTTGAAATCCTGTGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAA
CAAAAACACTTCCCTCGTTATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATG
ACAGTGGGAGGGGTACAAGGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTT
ATAGTTAGATCATATCCAATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATA
ATGGAGTTCCTCTCCTCTGCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGAT
GGGACTAATTGATATGCACCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCA
TGCTTGATTCCTACATTTTGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCA
CTACAAGTAAATCCCCCATTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACT

>36771_36771_67_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000354487_length(amino acids)=1356AA_BP=263
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGR
RKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENR
VNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDE
PEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLN
ENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNK
KAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREP
ELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLG
KKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLA
KKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQL
RERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLL
EVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNE
EKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQ
LSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKE

--------------------------------------------------------------
>36771_36771_68_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000405015_length(transcript)=4180nt_BP=912nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCAT
GTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACT
CAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGG
GAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAA
GAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTG
GATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGAC
TCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAG
ACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATA
AGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCT
AAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCA
GTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCA
AGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATC
ACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTG
AATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATG
GTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTT
CAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTAT
GCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTT
GTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGC
AGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACA
GATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAG
AAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAA
AAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGA
TACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACT
TTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTT
GAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGAT
CAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTT
CCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTG
AAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATG
AAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACA
GTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAG
AAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGT
CAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTAT
CTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGG
AGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCC
ATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCG
CTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATG
GCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGA

>36771_36771_68_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000405015_length(amino acids)=1320AA_BP=263
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGR
RKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENR
VNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDE
PEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLN
ENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNK
KAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREP
ELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLG
KKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLA
KKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQL
RERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTE
RLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAAL
ENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQ

--------------------------------------------------------------
>36771_36771_69_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000405289_length(transcript)=4191nt_BP=912nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCAT
GTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACT
CAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGG
GAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAA
GAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTG
GATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGAC
TCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAG
ACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATA
AGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCT
AAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCA
GTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCA
AGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATC
ACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTG
AATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATG
GTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTT
CAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTAT
GCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTT
GTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGC
AGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACA
GATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAG
AAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAA
AAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGA
TACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACT
TTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTT
GAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGAT
CAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTT
CCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGATGAAAATGATAATATTGAGATAGATACTAAC
GAGGAGATCCCTGAAGGCTTTGTTGTAGGAGGTGGAGATGAACTTACTAACTTAGAAAATGACCTTGATACTCCCGAACAAAACAGTAAG
TTGGTGGACTTGAAGCTGAAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAG
AGCTCAGAGCAGGACATGAAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTG
TTCAGCAAAGATTCTACAGTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCA
ATACAGGAAGATACAAAGAAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAA
GGGTTCAAAGACACCAGTCAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTG
GAGAAGCGCCTTCGCTATCTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAG
AAAAATGCCTTAATAAGGAGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAA
TTGAGGGCAATGCTAGCCATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTG
GTGAACAAGCGCGATGCGCTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAG

>36771_36771_69_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000405289_length(amino acids)=1356AA_BP=263
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGR
RKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENR
VNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDE
PEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLN
ENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNK
KAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREP
ELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLG
KKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLA
KKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQL
RERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGDENDNIEIDTNEEIPEGFVVGGGDELTNLENDLDTPEQNSKLVDLKLKKLL
EVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNE
EKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQ
LSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQEKQAEEEDEHLERTLEQNKGKMAKKE

--------------------------------------------------------------
>36771_36771_70_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000431489_length(transcript)=5070nt_BP=912nt
AGACTGTAGGACGACCTCGGGTCCCACGTGTCCCCGGTACTCGCCGGCCGGAGCCCCCGGCTTCCCGGGGCCGGGGGACCTTAGCGGCAC
CCACACACAGCCTACTTTCCAAGCGGAGCCATGTCTGGTAACGGCAATGCGGCTGCAACGGCGGAAGAAAACAGCCCAAAGATGAGAGTG
ATTCGCGTGGGTACCCGCAAGAGCCAGCTTGCTCGCATACAGACGGACAGTGTGGTGGCAACATTGAAAGCCTCGTACCCTGGCCTGCAG
TTTGAAATCATTGCTATGTCCACCACAGGGGACAAGATTCTTGATACTGCACTCTCTAAGATTGGAGAGAAAAGCCTGTTTACCAAGGAG
CTTGAACATGCCCTGGAGAAGAATGAAGTGGACCTGGTTGTTCACTCCTTGAAGGACCTGCCCACTGTGCTTCCTCCTGGCTTCACCATC
GGAGCCATCTGCAAGCGGGAAAACCCTCATGATGCTGTTGTCTTTCACCCAAAATTTGTTGGGAAGACCCTAGAAACCCTGCCAGAGAAG
AGTGTGGTGGGAACCAGCTCCCTGCGAAGAGCAGCCCAGCTGCAGAGAAAGTTCCCGCATCTGGAGTTCAGGAGTATTCGGGGAAACCTC
AACACCCGGCTTCGGAAGCTGGACGAGCAGCAGGAGTTCAGTGCCATCATCCTGGCAACAGCTGGCCTGCAGCGCATGGGCTGGCACAAC
CGGGTGGGGCAGATCCTGCACCCTGAGGAATGCATGTATGCTGTGGGCCAGGAAGGAGGCTGCAGTGTGCCAGTAGCCGTGCATACAGCT
ATGAAGGATGGGCAACTGTACCTGACTGGAGGAGTCTGGAGTCTAGACGGCTCAGATAGCATACAAGAGACCATGCAGGCTACCATCCAT
GTCCCTGCCCAGGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACT
CAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGG
GAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAA
GAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTG
GATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGAC
TCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAG
ACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATA
AGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCT
AAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCA
GTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGCCAAGCCCTATACCA
AGTCCTGTTTTGGGGCGAAAGCCAAATGCTAGTCAGTCTTTGCTTGTATGGTGTAAAGAAGTTACAAAGAACTACCGAGGAGTAAAAATC
ACCAATTTTACTACATCGTGGAGAAATGGTTTATCTTTTTGTGCAATATTACACCACTTTAGACCAGATTTAATTGACTACAAGTCTCTG
AATCCTCAAGATATTAAAGAGAACAACAAAAAGGCATACGATGGATTTGCCAGCATAGGAATTTCCCGATTATTGGAACCTTCTGATATG
GTATTATTAGCAATTCCTGATAAACTGACTGTTATGACTTATCTCTATCAAATAAGGGCACATTTCAGTGGCCAAGAACTAAATGTCGTT
CAGATAGAGGAAAACAGCAGTAAAAGCACATATAAAGTTGGAAACTATGAAACAGATACAAACAGTTCTGTTGATCAAGAAAAATTCTAT
GCAGAGCTTAGTGATCTGAAGCGGGAGCCTGAACTACAACAGCCTATCAGCGGAGCAGTAGACTTCTTATCACAGGATGACTCTGTATTT
GTAAATGATAGCGGGGTTGGAGAGTCAGAAAGTGAGCATCAAACTCCTGATGATCACCTTAGTCCAAGCACAGCCTCCCCTTACTGTCGC
AGGACTAAAAGTGACACAGAACCCCAGAAGTCTCAGCAGAGCTCTGGAAGGACTTCAGGATCTGATGACCCTGGAATATGTTCCAATACA
GATTCAACCCAAGCACAGGTTTTGTTAGGCAAAAAGAGACTATTGAAAGCTGAGACTTTAGAATTGAGTGACTTATATGTTAGTGATAAG
AAGAAGGATATGTCTCCACCCTTTATTTGTGAGGAGACAGATGAACAAAAGCTTCAAACTCTAGACATCGGTAGTAACTTGGAGAAAGAA
AAATTAGAGAATTCCAGATCCTTAGAATGCAGATCAGATCCAGAATCTCCTATCAAAAAAACAAGTTTATCTCCTACTTCTAAACTTGGA
TACTCATATAGTAGAGATCTAGACCTTGCTAAGAAAAAACATGCTTCCCTGAGGCAGACGGAGTCTGATCCAGATGCTGATAGAACCACT
TTAAATCATGCAGATCATTCATCAAAAATAGTCCAGCATCGATTGTTATCTAGACAAGAAGAACTTAAGGAAAGAGCAAGAGTTCTGCTT
GAGCAAGCAAGAAGAGATGCAGCCTTAAAGGCGGGGAATAAGCACAATACCAACACAGCCACCCCATTCTGCAACAGGCAGCTAAGTGAT
CAGCAAGATGAAGAGCGACGTCGGCAGCTGAGAGAGAGAGCTCGTCAGCTAATAGCAGAAGCTCGATCTGGAGTGAAGATGTCAGAACTT
CCCAGCTATGGTGAAATGGCTGCAGAAAAGTTGAAAGAAAGGTCAAAGGCATCTGGAGAACAAAACAGTAAGTTGGTGGACTTGAAGCTG
AAGAAGCTCCTAGAAGTTCAGCCACAGGTGGCAAATTCACCCTCCAGTGCTGCCCAGAAAGCTGTAACTGAGAGCTCAGAGCAGGACATG
AAAAGTGGCACAGAAGATCTCCGGACTGAACGATTACAAAAAACAACAGAACGTTTTAGAAATCCTGTTGTGTTCAGCAAAGATTCTACA
GTCAGAAAAACTCAACTTCAGTCTTTCAGCCAATATATTGAGAATAGACCAGAGATGAAAAGGCAGAGATCAATACAGGAAGATACAAAG
AAAGGAAATGAGGAGAAGGCAGCGATAACTGAAACTCAGAGGAAGCCATCAGAAGATGAAGTGCTTAATAAAGGGTTCAAAGACACCAGT
CAGTATGTAGTAGGAGAATTGGCAGCACTAGAGAATGAGCAAAAGCAAATTGACACCCGTGCCGCGCTGGTGGAGAAGCGCCTTCGCTAT
CTCATGGACACAGGAAGGAACACAGAAGAAGAAGAAGCTATGATGCAGGAATGGTTTATGTTAGTTAATAAGAAAAATGCCTTAATAAGG
AGAATGAATCAGCTCTCTCTTCTGGAAAAAGAACATGATTTAGAACGACGGTATGAGCTGCTGAACCGGGAATTGAGGGCAATGCTAGCC
ATTGAAGACTGGCAGAAGACCGAGGCCCAGAAGCGACGCGAACAGCTTCTGCTAGATGAGCTGGTGGCCCTGGTGAACAAGCGCGATGCG
CTCGTCAGGGACCTGGACGCGCAGGAGAAGCAGGCCGAAGAAGAAGATGAGCATTTGGAGCGAACTCTGGAGCAAAACAAAGGCAAGATG
GCCAAGAAAGAGGAGAAATGTGTTCTTCAGTAGCCATCAGATCAGAAAGAATCTCTCCCAACATTTTAGAGTCTTGCTTCCCAAACCAGA
AAAAGTCAGACTCATTGTTGATTTAAAACTTTTAACATTTTGTTTGGCTGGATTGTACTACTTTACCTCTACTTTACCACCACCACCCTT
TTCCTCCCTCCTTTCCAAATAATATACAGAACTCCAAAATAGCTTCATTTAAGGATTTTTTTGTGAGTTAACAATTTCCTTGAAATCCTG
TGAAATAGATTTGCACAGACACCTTGTGAGTGATTGGTATTGGAGGTGTTCAAGAAACTGTTCGAAAAAGAACAAAAACACTTCCCTCGT
TATTTTCTCTCATTTTTTGATGAGAGGAAAATTTGAAACATTATTCTTGTTGTTGTTGGTAATAGCATAATGACAGTGGGAGGGGTACAA
GGGGATAAGAAAAATGTCATGATTTTTTTCCGGTCCTGCCACATGTAACACTTACTCTGTTACCTAAATTTTATAGTTAGATCATATCCA
ATCTACTTATTAAACTGTGTTCTATTTACCAGTGGAGTTTTTCTGCAGTGGTTGCGTTTCACTGTAAGGATAATGGAGTTCCTCTCCTCT
GCTTTCCTCAGAGGATGGTCCTTTAACATAGCCAGAAACAAGCCCTGTGGTTTGAAGGTGAGCTGTGAGGATGGGACTAATTGATATGCA
CCAGTTTACAAAGACAGTCTTATCATCCGAGAATACACCATCTTTTTCTCTGGATAATTATTTCTTACATCATGCTTGATTCCTACATTT
TGTTGGGTCTCAACATTGGCTCACGAATGCTGTTAATATTTATTCTGTATTGATAAAAAGTCTGTCTTGCCACTACAAGTAAATCCCCCA
TTTAATATTTTCTTCTTTAGCATAGCACTGTCATTTTTTGTGAAAATGGTTATGTTTATTTATTACAATACTGAGTCATATATAAATTTT

>36771_36771_70_HMBS-EHBP1_HMBS_chr11_118963731_ENST00000544387_EHBP1_chr2_63053222_ENST00000431489_length(amino acids)=1320AA_BP=263
MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEV
DLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQ
QEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQESPSGR
RKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQADIGNLDDFEEDNEDDDENR
VNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDE
PEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLN
ENTVSAGKDLSTSPKPSPIPSPVLGRKPNASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNK
KAYDGFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQELNVVQIEENSSKSTYKVGNYETDTNSSVDQEKFYAELSDLKREP
ELQQPISGAVDFLSQDDSVFVNDSGVGESESEHQTPDDHLSPSTASPYCRRTKSDTEPQKSQQSSGRTSGSDDPGICSNTDSTQAQVLLG
KKRLLKAETLELSDLYVSDKKKDMSPPFICEETDEQKLQTLDIGSNLEKEKLENSRSLECRSDPESPIKKTSLSPTSKLGYSYSRDLDLA
KKKHASLRQTESDPDADRTTLNHADHSSKIVQHRLLSRQEELKERARVLLEQARRDAALKAGNKHNTNTATPFCNRQLSDQQDEERRRQL
RERARQLIAEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLEVQPQVANSPSSAAQKAVTESSEQDMKSGTEDLRTE
RLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVVGELAAL
ENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for HMBS-EHBP1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for HMBS-EHBP1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for HMBS-EHBP1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	HMBS	C0162565	Acute intermittent porphyria	45	CTD_human;GENOMICS_ENGLAND;UNIPROT
Hgene	HMBS	C2936779	Hydroxymethylbilane Synthase Deficiency	2	CTD_human
Tgene		C0033578	Prostatic Neoplasms	1	CTD_human
Tgene		C0376358	Malignant neoplasm of prostate	1	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:HMBS-EHBP1 (FusionGDB2 ID:HG3145TG23301)

Fusion Gene Summary for HMBS-EHBP1

Fusion Gene ORF analysis for HMBS-EHBP1

Fusion Genomic Features for HMBS-EHBP1

Fusion Protein Features for HMBS-EHBP1

Fusion Gene Sequence for HMBS-EHBP1

Fusion Gene PPI Analysis for HMBS-EHBP1

Related Drugs for HMBS-EHBP1

Related Diseases for HMBS-EHBP1

Fusion Gene Studies
in Kim Lab