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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:NCKAP5-DYNC2H1 (FusionGDB2 ID:HG344148TG79659)

Fusion Gene Summary for NCKAP5-DYNC2H1

check button Fusion gene summary
Fusion gene informationFusion gene name: NCKAP5-DYNC2H1
Fusion gene ID: hg344148tg79659
HgeneTgene
Gene symbol

NCKAP5

DYNC2H1

Gene ID

344148

79659

Gene nameNCK associated protein 5dynein cytoplasmic 2 heavy chain 1
SynonymsERIH1|ERIH2|NAP5ATD3|DHC1b|DHC2|DNCH2|DYH1B|SRPS2B|SRTD3|hdhc11
Cytomap('NCKAP5')('DYNC2H1')

2q21.2

11q22.3

Type of geneprotein-codingprotein-coding
Descriptionnck-associated protein 5NAP-5peripheral clock protein 2cytoplasmic dynein 2 heavy chain 1dynein cytoplasmic heavy chain 2dynein heavy chain 11dynein heavy chain, isotype 1Bdynein, cytoplasmic, heavy polypeptide 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000409213, ENST00000409261, 
ENST00000317721, ENST00000405974, 
ENST00000473859, 
Fusion gene scores* DoF score15 X 14 X 7=147016 X 17 X 9=2448
# samples 1918
** MAII scorelog2(19/1470*10)=-2.95174483139278
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/2448*10)=-3.76553474636298
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NCKAP5 [Title/Abstract] AND DYNC2H1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointNCKAP5(133971288)-DYNC2H1(103306671), # samples:4
Anticipated loss of major functional domain due to fusion event.NCKAP5-DYNC2H1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NCKAP5-DYNC2H1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
NCKAP5-DYNC2H1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
NCKAP5-DYNC2H1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
NCKAP5-DYNC2H1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDYNC2H1

GO:0007030

Golgi organization

8666668


check buttonFusion gene breakpoints across NCKAP5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across DYNC2H1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-FG-5963-01ANCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
ChimerDB4LGGTCGA-FG-5963-02ANCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
ChimerDB4LGGTCGA-FG-5963NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
ChimerDB4LGGTCGA-FG-5963NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+


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Fusion Gene ORF analysis for NCKAP5-DYNC2H1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000409213ENST00000334267NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409213ENST00000334267NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
Frame-shiftENST00000409213ENST00000375735NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409213ENST00000375735NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
Frame-shiftENST00000409213ENST00000398093NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409213ENST00000398093NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
Frame-shiftENST00000409261ENST00000334267NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409261ENST00000334267NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
Frame-shiftENST00000409261ENST00000375735NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409261ENST00000375735NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
Frame-shiftENST00000409261ENST00000398093NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
Frame-shiftENST00000409261ENST00000398093NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000317721ENST00000334267NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000317721ENST00000334267NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000317721ENST00000375735NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000317721ENST00000375735NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000317721ENST00000398093NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000317721ENST00000398093NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000405974ENST00000334267NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000405974ENST00000334267NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000405974ENST00000375735NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000405974ENST00000375735NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
In-frameENST00000405974ENST00000398093NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
In-frameENST00000405974ENST00000398093NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
intron-3CDSENST00000473859ENST00000334267NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
intron-3CDSENST00000473859ENST00000334267NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
intron-3CDSENST00000473859ENST00000375735NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
intron-3CDSENST00000473859ENST00000375735NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+
intron-3CDSENST00000473859ENST00000398093NCKAP5chr2

133971288

-DYNC2H1chr11

103306671

+
intron-3CDSENST00000473859ENST00000398093NCKAP5chr2

133971287

-DYNC2H1chr11

103306670

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000405974NCKAP5chr2133971288-ENST00000375735DYNC2H1chr11103306671+13752070764254
ENST00000405974NCKAP5chr2133971288-ENST00000334267DYNC2H1chr11103306671+9332070764254
ENST00000405974NCKAP5chr2133971288-ENST00000398093DYNC2H1chr11103306671+7652070764254
ENST00000317721NCKAP5chr2133971288-ENST00000375735DYNC2H1chr11103306671+13752070764254
ENST00000317721NCKAP5chr2133971288-ENST00000334267DYNC2H1chr11103306671+9332070764254
ENST00000317721NCKAP5chr2133971288-ENST00000398093DYNC2H1chr11103306671+7652070764254
ENST00000405974NCKAP5chr2133971287-ENST00000375735DYNC2H1chr11103306670+13752070764254
ENST00000405974NCKAP5chr2133971287-ENST00000334267DYNC2H1chr11103306670+9332070764254
ENST00000405974NCKAP5chr2133971287-ENST00000398093DYNC2H1chr11103306670+7652070764254
ENST00000317721NCKAP5chr2133971287-ENST00000375735DYNC2H1chr11103306670+13752070764254
ENST00000317721NCKAP5chr2133971287-ENST00000334267DYNC2H1chr11103306670+9332070764254
ENST00000317721NCKAP5chr2133971287-ENST00000398093DYNC2H1chr11103306670+7652070764254

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000405974ENST00000375735NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0008775670.99912244
ENST00000405974ENST00000334267NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0018859540.9981141
ENST00000405974ENST00000398093NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0038274390.9961726
ENST00000317721ENST00000375735NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0008775670.99912244
ENST00000317721ENST00000334267NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0018859540.9981141
ENST00000317721ENST00000398093NCKAP5chr2133971288-DYNC2H1chr11103306671+0.0038274390.9961726
ENST00000405974ENST00000375735NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0008775670.99912244
ENST00000405974ENST00000334267NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0018859540.9981141
ENST00000405974ENST00000398093NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0038274390.9961726
ENST00000317721ENST00000375735NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0008775670.99912244
ENST00000317721ENST00000334267NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0018859540.9981141
ENST00000317721ENST00000398093NCKAP5chr2133971287-DYNC2H1chr11103306670+0.0038274390.9961726

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Fusion Genomic Features for NCKAP5-DYNC2H1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257
NCKAP5chr2133971287-DYNC2H1chr11103306670+3.74E-050.99996257

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for NCKAP5-DYNC2H1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:133971288/chr11:103306671)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201074_1103735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202897_2982735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714203109_3200735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714203408_3442735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201074_1103735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202897_2982735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714203109_3200735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714203408_3442735921.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201689_1696735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201979_1986735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202291_2298735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202655_2662735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201689_1696735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201979_1986735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202291_2298735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202655_2662735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201651_1875735921.0RegionAAA 1
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201938_2161735921.0RegionAAA 2
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202251_2505735921.0RegionAAA 3
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202617_2863735921.0RegionAAA 4
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714202881_3169735921.0RegionStalk
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714203244_3473735921.0RegionAAA 5
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714203690_3905735921.0RegionAAA 6
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201651_1875735921.0RegionAAA 1
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201938_2161735921.0RegionAAA 2
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202251_2505735921.0RegionAAA 3
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202617_2863735921.0RegionAAA 4
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714202881_3169735921.0RegionStalk
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714203244_3473735921.0RegionAAA 5
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714203690_3905735921.0RegionAAA 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000317721-31871_253691910.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000405974-31671_25369591.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409213-51871_25369591.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409261-52071_253691910.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000317721-31871_253691910.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000405974-31671_25369591.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409213-51871_25369591.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409261-52071_253691910.0Coiled coilOntology_term=ECO:0000255
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000317721-3181080_1130691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000317721-318331_386691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000317721-318927_933691910.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000405974-3161080_113069591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000405974-316331_38669591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000405974-316927_93369591.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409213-5181080_113069591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409213-518331_38669591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409213-518927_93369591.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409261-5201080_1130691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409261-520331_386691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971287chr11:103306670ENST00000409261-520927_933691910.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000317721-3181080_1130691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000317721-318331_386691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000317721-318927_933691910.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000405974-3161080_113069591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000405974-316331_38669591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000405974-316927_93369591.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409213-5181080_113069591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409213-518331_38669591.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409213-518927_93369591.0Compositional biasNote=Poly-Pro
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409261-5201080_1130691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409261-520331_386691910.0Compositional biasNote=Ser-rich
HgeneNCKAP5chr2:133971288chr11:103306671ENST00000409261-520927_933691910.0Compositional biasNote=Poly-Pro
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891074_110341224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892897_298241224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583893109_320041224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583893408_344241224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901074_110341294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902897_298241294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384903109_320041294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384903408_344241294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891074_110341224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892897_298241224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583893109_320041224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583893408_344241224308.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901074_110341294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902897_298241294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384903109_320041294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384903408_344241294315.0Coiled coilOntology_term=ECO:0000255
TgeneDYNC2H1chr2:133971287chr11:103306670ENST000003342671420145_152735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST000003757358389145_15241224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891689_169641224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891979_198641224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892291_229841224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892655_266241224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST000003980938490145_15241294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901689_169641294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901979_198641294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902291_229841294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902655_266241294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST000003342671420145_152735921.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST000003757358389145_15241224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891689_169641224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891979_198641224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892291_229841224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892655_266241224308.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST000003980938490145_15241294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901689_169641294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901979_198641294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902291_229841294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902655_266241294315.0Nucleotide bindingATP
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000033426714201_1650735921.0RegionStem
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891651_187541224308.0RegionAAA 1
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891938_216141224308.0RegionAAA 2
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583891_165041224308.0RegionStem
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892251_250541224308.0RegionAAA 3
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892617_286341224308.0RegionAAA 4
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583892881_316941224308.0RegionStalk
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583893244_347341224308.0RegionAAA 5
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000037573583893690_390541224308.0RegionAAA 6
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901651_187541294315.0RegionAAA 1
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901938_216141294315.0RegionAAA 2
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384901_165041294315.0RegionStem
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902251_250541294315.0RegionAAA 3
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902617_286341294315.0RegionAAA 4
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384902881_316941294315.0RegionStalk
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384903244_347341294315.0RegionAAA 5
TgeneDYNC2H1chr2:133971287chr11:103306670ENST0000039809384903690_390541294315.0RegionAAA 6
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000033426714201_1650735921.0RegionStem
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891651_187541224308.0RegionAAA 1
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891938_216141224308.0RegionAAA 2
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583891_165041224308.0RegionStem
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892251_250541224308.0RegionAAA 3
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892617_286341224308.0RegionAAA 4
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583892881_316941224308.0RegionStalk
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583893244_347341224308.0RegionAAA 5
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000037573583893690_390541224308.0RegionAAA 6
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901651_187541294315.0RegionAAA 1
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901938_216141294315.0RegionAAA 2
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384901_165041294315.0RegionStem
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902251_250541294315.0RegionAAA 3
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902617_286341294315.0RegionAAA 4
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384902881_316941294315.0RegionStalk
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384903244_347341294315.0RegionAAA 5
TgeneDYNC2H1chr2:133971288chr11:103306671ENST0000039809384903690_390541294315.0RegionAAA 6


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Fusion Gene Sequence for NCKAP5-DYNC2H1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>57629_57629_1_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000334267_length(transcript)=933nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG

>57629_57629_1_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000334267_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_2_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000375735_length(transcript)=1375nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG
AAATTTTAATGTGTAAAAGCAGCACTGTGCATCTTTTAAAGTAATAAATTAATGGAGTTATTGTTAAAACAGAGTATTCTTTTGACAACA
TTAAATATTTCTGTGAGAAAGTTCACTTTTCCAGTGGCTCAAAAATTTGTTTTAGGTCAGAGATTTTAAGTGGTATATTAACCAATAATA
AATATTTTGGCTGTCATTTGTGTCATAATTATTTAATAAAAGAGCATTCATAATTTTTGCAGTCTTCCCATGACTCTTTTTACATACTGA
AGAATGTATTATAAAGTTATAATGAATGTATAAAAGTATCAACATGAATATAATTATACTATGCTAATTATAATATACAAATATATAATT
ATTGTCATAATTATATACTTATAACTAATATCTTAAGGTAATTCAAATAGGAATAATTCAGGTGACATAATAATGGAGGATAAATTCTGG

>57629_57629_2_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000375735_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_3_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000398093_length(transcript)=765nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC

>57629_57629_3_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000317721_DYNC2H1_chr11_103306670_ENST00000398093_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_4_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000334267_length(transcript)=933nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG

>57629_57629_4_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000334267_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_5_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000375735_length(transcript)=1375nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG
AAATTTTAATGTGTAAAAGCAGCACTGTGCATCTTTTAAAGTAATAAATTAATGGAGTTATTGTTAAAACAGAGTATTCTTTTGACAACA
TTAAATATTTCTGTGAGAAAGTTCACTTTTCCAGTGGCTCAAAAATTTGTTTTAGGTCAGAGATTTTAAGTGGTATATTAACCAATAATA
AATATTTTGGCTGTCATTTGTGTCATAATTATTTAATAAAAGAGCATTCATAATTTTTGCAGTCTTCCCATGACTCTTTTTACATACTGA
AGAATGTATTATAAAGTTATAATGAATGTATAAAAGTATCAACATGAATATAATTATACTATGCTAATTATAATATACAAATATATAATT
ATTGTCATAATTATATACTTATAACTAATATCTTAAGGTAATTCAAATAGGAATAATTCAGGTGACATAATAATGGAGGATAAATTCTGG

>57629_57629_5_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000375735_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_6_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000398093_length(transcript)=765nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC

>57629_57629_6_NCKAP5-DYNC2H1_NCKAP5_chr2_133971287_ENST00000405974_DYNC2H1_chr11_103306670_ENST00000398093_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_7_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000334267_length(transcript)=933nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG

>57629_57629_7_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000334267_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_8_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000375735_length(transcript)=1375nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG
AAATTTTAATGTGTAAAAGCAGCACTGTGCATCTTTTAAAGTAATAAATTAATGGAGTTATTGTTAAAACAGAGTATTCTTTTGACAACA
TTAAATATTTCTGTGAGAAAGTTCACTTTTCCAGTGGCTCAAAAATTTGTTTTAGGTCAGAGATTTTAAGTGGTATATTAACCAATAATA
AATATTTTGGCTGTCATTTGTGTCATAATTATTTAATAAAAGAGCATTCATAATTTTTGCAGTCTTCCCATGACTCTTTTTACATACTGA
AGAATGTATTATAAAGTTATAATGAATGTATAAAAGTATCAACATGAATATAATTATACTATGCTAATTATAATATACAAATATATAATT
ATTGTCATAATTATATACTTATAACTAATATCTTAAGGTAATTCAAATAGGAATAATTCAGGTGACATAATAATGGAGGATAAATTCTGG

>57629_57629_8_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000375735_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_9_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000398093_length(transcript)=765nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC

>57629_57629_9_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000317721_DYNC2H1_chr11_103306671_ENST00000398093_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_10_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000334267_length(transcript)=933nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG

>57629_57629_10_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000334267_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_11_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000375735_length(transcript)=1375nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC
CAGTGGATTCAGTGTGGAGCAGCTCTATTCCTAAAAAATCAGTAGAATCTAATGACAACAAAAGCCATCTTCACAAAAGGGAACATTGAT
TCTTTAAGCTTTAAATCAAACATGTGGTCAGTCTACATTTGAAATGTTAGTTCAAAATATTAACATATAGTTATGTTGTTGATGTCACTG
AAATTTTAATGTGTAAAAGCAGCACTGTGCATCTTTTAAAGTAATAAATTAATGGAGTTATTGTTAAAACAGAGTATTCTTTTGACAACA
TTAAATATTTCTGTGAGAAAGTTCACTTTTCCAGTGGCTCAAAAATTTGTTTTAGGTCAGAGATTTTAAGTGGTATATTAACCAATAATA
AATATTTTGGCTGTCATTTGTGTCATAATTATTTAATAAAAGAGCATTCATAATTTTTGCAGTCTTCCCATGACTCTTTTTACATACTGA
AGAATGTATTATAAAGTTATAATGAATGTATAAAAGTATCAACATGAATATAATTATACTATGCTAATTATAATATACAAATATATAATT
ATTGTCATAATTATATACTTATAACTAATATCTTAAGGTAATTCAAATAGGAATAATTCAGGTGACATAATAATGGAGGATAAATTCTGG

>57629_57629_11_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000375735_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------
>57629_57629_12_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000398093_length(transcript)=765nt_BP=207nt
ATGGAGGGAAAGAGACAGCTTGAGAAAAGGGACTTTGGAAAAAGGCTGTCTCTAGACAGCAGTCTTGTGGAATACATGGACTCCAATAAA
TACATTGAGCATCTGCTGACTCAGCTTGAGGAGCAACACAGGAGTCTCTGGAGGGAGAAGTTGGCAGTGGCCCGACTACAGCGAGAAGTT
GCCCAAAGAACAAGTGAGGGGGCCATGTGTCCTCTCGCATGGCAGAGCAAGTGGGAAGGCCCAGAAGATCCCTTACAATACCTGAGAGGT
CTTGTTGCCCGTGCCCTTGCAATACAGAACTGGGTAGATAAAGCTGAAAAACAGGCTCTTCTCTCTGAAACACTTGACCTATCAGAACTT
TTCCATCCAGACACATTTCTTAATGCTCTTCGCCAGGAAACTGCAAGGGCAGTGGGTCGTTCTGTGGATAGCCTTAAATTTGTAGCCTCA
TGGAAAGGTCGACTGCAAGAAGCAAAGCTACAAATTAAGATCAGTGGCTTGTTACTAGAAGGATGTAGTTTTGATGGAAATCAACTTTCT
GAAAATCAGCTTGATTCTCCCAGCGTGTCATCAGTGCTCCCTTGTTTTATGGGCTGGATTCCACAGGATGCATGTGGTCCATATTCTCCG
GATGAGTGCATCTCTTTGCCTGTTTACACAAGTGCTGAAAGGGATCGTGTGGTTACCAATATTGATGTTCCATGTGGGGGCAACCAAGAC

>57629_57629_12_NCKAP5-DYNC2H1_NCKAP5_chr2_133971288_ENST00000405974_DYNC2H1_chr11_103306671_ENST00000398093_length(amino acids)=254AA_BP=69
MEGKRQLEKRDFGKRLSLDSSLVEYMDSNKYIEHLLTQLEEQHRSLWREKLAVARLQREVAQRTSEGAMCPLAWQSKWEGPEDPLQYLRG
LVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQEAKLQIKISGLLLEGCSFDGNQLS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for NCKAP5-DYNC2H1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NCKAP5-DYNC2H1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NCKAP5-DYNC2H1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneNCKAP5C0086132Depressive Symptoms1PSYGENET
TgeneC0036069Saldino-Noonan Syndrome7CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0024507Majewski Syndrome3CTD_human;ORPHANET
TgeneC0265275Jeune thoracic dystrophy2GENOMICS_ENGLAND;ORPHANET
TgeneC0432197Short rib-polydactyly syndrome, Verma-Naumoff type2CTD_human;ORPHANET
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0036996Short Rib-Polydactyly Syndrome1CTD_human
TgeneC0152427Polydactyly1GENOMICS_ENGLAND
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human