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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARSB-COMMD7 (FusionGDB2 ID:HG411TG149951)

Fusion Gene Summary for ARSB-COMMD7

check button Fusion gene summary
Fusion gene informationFusion gene name: ARSB-COMMD7
Fusion gene ID: hg411tg149951
HgeneTgene
Gene symbol

ARSB

COMMD7

Gene ID

411

149951

Gene namearylsulfatase BCOMM domain containing 7
SynonymsASB|G4S|MPS6C20orf92|dJ1085F17.3
Cytomap('ARSB')('COMMD7')

5q14.1

20q11.21

Type of geneprotein-codingprotein-coding
Descriptionarylsulfatase BN-acetylgalactosamine-4-sulfataseCOMM domain-containing protein 7
Modification date2020031320200313
UniProtAcc

P15848

.
Ensembl transtripts involved in fusion geneENST00000396151, ENST00000565165, 
ENST00000264914, ENST00000521800, 
Fusion gene scores* DoF score5 X 5 X 3=757 X 5 X 6=210
# samples 59
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(9/210*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARSB [Title/Abstract] AND COMMD7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARSB(78251117)-COMMD7(31294562), # samples:1
Anticipated loss of major functional domain due to fusion event.ARSB-COMMD7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARSB-COMMD7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARSB-COMMD7 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCOMMD7

GO:0032088

negative regulation of NF-kappaB transcription factor activity

15799966

TgeneCOMMD7

GO:0033209

tumor necrosis factor-mediated signaling pathway

15799966

TgeneCOMMD7

GO:0045892

negative regulation of transcription, DNA-templated

15799966


check buttonFusion gene breakpoints across ARSB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across COMMD7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer201NARSBchr5

78251117

-COMMD7chr20

31294562

-


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Fusion Gene ORF analysis for ARSB-COMMD7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000396151ENST00000278980ARSBchr5

78251117

-COMMD7chr20

31294562

-
Frame-shiftENST00000396151ENST00000446419ARSBchr5

78251117

-COMMD7chr20

31294562

-
Frame-shiftENST00000565165ENST00000278980ARSBchr5

78251117

-COMMD7chr20

31294562

-
Frame-shiftENST00000565165ENST00000446419ARSBchr5

78251117

-COMMD7chr20

31294562

-
In-frameENST00000264914ENST00000278980ARSBchr5

78251117

-COMMD7chr20

31294562

-
In-frameENST00000264914ENST00000446419ARSBchr5

78251117

-COMMD7chr20

31294562

-
intron-3CDSENST00000521800ENST00000278980ARSBchr5

78251117

-COMMD7chr20

31294562

-
intron-3CDSENST00000521800ENST00000446419ARSBchr5

78251117

-COMMD7chr20

31294562

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000264914ARSBchr578251117-ENST00000278980COMMD7chr2031294562-248814352701796508
ENST00000264914ARSBchr578251117-ENST00000446419COMMD7chr2031294562-247614352701796508

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000264914ENST00000278980ARSBchr578251117-COMMD7chr2031294562-0.0026798770.9973201
ENST00000264914ENST00000446419ARSBchr578251117-COMMD7chr2031294562-0.002724620.9972754

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Fusion Genomic Features for ARSB-COMMD7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARSB-COMMD7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:78251117/chr20:31294562)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARSB

P15848

.
FUNCTION: Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity). {ECO:0000250|UniProtKB:P50430, ECO:0000269|PubMed:19306108}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCOMMD7chr5:78251117chr20:31294562ENST0000027898029133_20080201.0DomainCOMM
TgeneCOMMD7chr5:78251117chr20:31294562ENST0000044641929133_20079200.0DomainCOMM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for ARSB-COMMD7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6874_6874_1_ARSB-COMMD7_ARSB_chr5_78251117_ENST00000264914_COMMD7_chr20_31294562_ENST00000278980_length(transcript)=2488nt_BP=1435nt
CTGCCACAGGCTGGGCTCTTGTGCTAGAAATGACTTGCTAGCTAGACATCATGGTTCAGGATCTGAGTCAGAGGTTTAACCATTTATAAG
CTTTTTTCTTATGAAAAATTGGCACTAATTATAATGTCTAACTGTCAGAGTTGTTGCAGGCTTTACAGGAGACGCGGGCTGTGAAGATGC
TTTGTAAATTGTGAAGCGTTATTAAAGAACACATCTTTTTTTTTTAGGAAACCACAGTGCAAATTTAATTGCCGGGGAAGATAACGGGCC
TTGGTGCCCTCCAAGCGTCAGCTGAGTTTCCAAGAAGCCGGGCAGCGGGCGCCCGCGGGTTCGTCTCTGGCTCCTCCTCCGCCACAGCAG
CCGGGGGCCCGGGTCGGAGGCGGCGGGGGCCGAGCGCCCGGCCTCGCAAGCCCACGGCCCGCTGGGGGTGCCGTCCCGCGCCGGGGCGGA
GCAGGCCCCGGCAGCCCAGTTCCTCATTCTATCAGCGGTACAAGGGGCTGGTGGCGCCACAGGCGCTGGGACCGCGGGCGGACAAGGATG
GGTCCGCGCGGCGCGGCGAGCTTGCCCCGAGGCCCCGGACCTCGGCGGCTGCTCCTCCCCGTCGTCCTCCCGCTGCTGCTGCTGCTGTTG
TTGGCGCCGCCGGGCTCGGGCGCCGGGGCCAGCCGGCCGCCCCACCTGGTCTTCTTGCTGGCAGACGACCTAGGCTGGAACGACGTCGGC
TTCCACGGCTCCCGCATCCGCACGCCGCACCTGGACGCGCTGGCGGCCGGCGGGGTGCTCCTGGACAACTACTACACGCAGCCGCTGTGC
ACGCCGTCGCGGAGCCAGCTGCTCACTGGCCGCTACCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGT
GTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTAC
CGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGT
ACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCA
ACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTG
CATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCC
CTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGGTGCT
TTGAAGAAGAGTCTCACAGCCAAGCAGGTCCAGGCGGATTTCATAACTCTGGGTCTTAGTGAGGAGAAAGCCACTTACTTTTCTGAAAAG
TGGAAGCAGAATGCTCCCACCCTTGCTCGATGGGCCATAGGTCAGACTCTGATGATTAACCAGCTCATAGATATGGAGTGGAAATTTGGA
GTGACATCTGGGAGCAGCGAATTGGAGAAAGTGGGAAGTATATTTTTACAACTAAAGTTGGTGGTTAAGAAAGGAAATCAAACCGAAAAT
GTGTATATAGAATTAACCTTGCCTCAGTTCTACAGCTTCCTGCACGAGATGGAGCGAGTCAGAACCAGCATGGAGTGTTTCTGCTGATTT
CTGTCCCTGCATCTCCCCTGGCCCCGTTCCCTGCCCTCCTCCCTTCCCTGGGTGACTGCTCTGAGAGGCACTTCACTCACAGGCCTGTGG
GATGCTCCATGGGGCCCTGCTGGCTCCATGGGGCCCAGGTGCAAAGGGTTTCTGAAAAACAGCAGGATTAAGTACTGAAAGAGCCCAACA
CAATTACCCTGTAAACTCTCTGTTAGGGCAACCACCACCACCTGTCTTCCAGGACACATTTTTAGATACTCTGACAGGCCACTGCATCTC
AGATTCAGGGGAGAAAATAAGTTGTCACCTCCCCTTCAAAGTTCCAGAGTAAACAAATGGTGCCATCATTCAAGATAACATGCTGATCAC
CCTCCTCCCAAAAAGCAAGAGCTTGTTTATGGCTGAGGAATCGGCGGATTGTCTGAATGACACATATACAGAGCCCCCACGGATTTCTGC
ACACTCTGGGTCTGTGCTGGTGGAACATTGCCAATCAGTTCTTAATGAGGCACCTGTGTGTAAATACATGCTTGGTCTTCTCTGCAGAGA
ACTGAGGCTAAACTCTGTCCCTACTTCTGGTTTTGCCCTGTCATGTCGTAACGAGGTGGGCCTTTTGAGGCCATTTTAGTTTGAGTTCGA

>6874_6874_1_ARSB-COMMD7_ARSB_chr5_78251117_ENST00000264914_COMMD7_chr20_31294562_ENST00000278980_length(amino acids)=508AA_BP=388
MVPSKRQLSFQEAGQRAPAGSSLAPPPPQQPGARVGGGGGRAPGLASPRPAGGAVPRRGGAGPGSPVPHSISGTRGWWRHRRWDRGRTRM
GPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLC
TPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERC
TLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVS
LMDEAVGNVTAALKSSGLWNNTVFIFSTGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFG

--------------------------------------------------------------
>6874_6874_2_ARSB-COMMD7_ARSB_chr5_78251117_ENST00000264914_COMMD7_chr20_31294562_ENST00000446419_length(transcript)=2476nt_BP=1435nt
CTGCCACAGGCTGGGCTCTTGTGCTAGAAATGACTTGCTAGCTAGACATCATGGTTCAGGATCTGAGTCAGAGGTTTAACCATTTATAAG
CTTTTTTCTTATGAAAAATTGGCACTAATTATAATGTCTAACTGTCAGAGTTGTTGCAGGCTTTACAGGAGACGCGGGCTGTGAAGATGC
TTTGTAAATTGTGAAGCGTTATTAAAGAACACATCTTTTTTTTTTAGGAAACCACAGTGCAAATTTAATTGCCGGGGAAGATAACGGGCC
TTGGTGCCCTCCAAGCGTCAGCTGAGTTTCCAAGAAGCCGGGCAGCGGGCGCCCGCGGGTTCGTCTCTGGCTCCTCCTCCGCCACAGCAG
CCGGGGGCCCGGGTCGGAGGCGGCGGGGGCCGAGCGCCCGGCCTCGCAAGCCCACGGCCCGCTGGGGGTGCCGTCCCGCGCCGGGGCGGA
GCAGGCCCCGGCAGCCCAGTTCCTCATTCTATCAGCGGTACAAGGGGCTGGTGGCGCCACAGGCGCTGGGACCGCGGGCGGACAAGGATG
GGTCCGCGCGGCGCGGCGAGCTTGCCCCGAGGCCCCGGACCTCGGCGGCTGCTCCTCCCCGTCGTCCTCCCGCTGCTGCTGCTGCTGTTG
TTGGCGCCGCCGGGCTCGGGCGCCGGGGCCAGCCGGCCGCCCCACCTGGTCTTCTTGCTGGCAGACGACCTAGGCTGGAACGACGTCGGC
TTCCACGGCTCCCGCATCCGCACGCCGCACCTGGACGCGCTGGCGGCCGGCGGGGTGCTCCTGGACAACTACTACACGCAGCCGCTGTGC
ACGCCGTCGCGGAGCCAGCTGCTCACTGGCCGCTACCAGATCCGTACAGGTTTACAGCACCAAATAATCTGGCCCTGTCAGCCCAGCTGT
GTTCCTCTGGATGAAAAACTCCTGCCCCAGCTCCTAAAAGAAGCAGGTTATACTACCCATATGGTCGGAAAATGGCACCTGGGAATGTAC
CGGAAAGAATGCCTTCCAACCCGCCGAGGATTTGATACCTACTTTGGATATCTCCTGGGTAGTGAAGATTATTATTCCCATGAACGCTGT
ACATTAATTGACGCTCTGAATGTCACACGATGTGCTCTTGATTTTCGAGATGGCGAAGAAGTTGCAACAGGATATAAAAATATGTATTCA
ACAAACATATTCACCAAAAGGGCTATAGCCCTCATAACTAACCATCCACCAGAGAAGCCTCTGTTTCTCTACCTTGCTCTCCAGTCTGTG
CATGAGCCCCTTCAGGTCCCTGAGGAATACTTGAAGCCATATGACTTTATCCAAGACAAGAACAGGCATCACTATGCAGGAATGGTGTCC
CTTATGGATGAAGCAGTAGGAAATGTCACTGCAGCTTTAAAAAGCAGTGGGCTCTGGAACAACACGGTGTTCATCTTTTCTACAGGTGCT
TTGAAGAAGAGTCTCACAGCCAAGCAGGTCCAGGCGGATTTCATAACTCTGGGTCTTAGTGAGGAGAAAGCCACTTACTTTTCTGAAAAG
TGGAAGCAGAATGCTCCCACCCTTGCTCGATGGGCCATAGGTCAGACTCTGATGATTAACCAGCTCATAGATATGGAGTGGAAATTTGGA
GTGACATCTGGGAGCAGCGAATTGGAGAAAGTGGGAAGTATATTTTTACAACTAAAGTTGGTGGTTAAGAAAGGAAATCAAACCGAAAAT
GTGTATATAGAATTAACCTTGCCTCAGTTCTACAGCTTCCTGCACGAGATGGAGCGAGTCAGAACCAGCATGGAGTGTTTCTGCTGATTT
CTGTCCCTGCATCTCCCCTGGCCCCGTTCCCTGCCCTCCTCCCTTCCCTGGGTGACTGCTCTGAGAGGCACTTCACTCACAGGCCTGTGG
GATGCTCCATGGGGCCCTGCTGGCTCCATGGGGCCCAGGTGCAAAGGGTTTCTGAAAAACAGCAGGATTAAGTACTGAAAGAGCCCAACA
CAATTACCCTGTAAACTCTCTGTTAGGGCAACCACCACCACCTGTCTTCCAGGACACATTTTTAGATACTCTGACAGGCCACTGCATCTC
AGATTCAGGGGAGAAAATAAGTTGTCACCTCCCCTTCAAAGTTCCAGAGTAAACAAATGGTGCCATCATTCAAGATAACATGCTGATCAC
CCTCCTCCCAAAAAGCAAGAGCTTGTTTATGGCTGAGGAATCGGCGGATTGTCTGAATGACACATATACAGAGCCCCCACGGATTTCTGC
ACACTCTGGGTCTGTGCTGGTGGAACATTGCCAATCAGTTCTTAATGAGGCACCTGTGTGTAAATACATGCTTGGTCTTCTCTGCAGAGA
ACTGAGGCTAAACTCTGTCCCTACTTCTGGTTTTGCCCTGTCATGTCGTAACGAGGTGGGCCTTTTGAGGCCATTTTAGTTTGAGTTCGA

>6874_6874_2_ARSB-COMMD7_ARSB_chr5_78251117_ENST00000264914_COMMD7_chr20_31294562_ENST00000446419_length(amino acids)=508AA_BP=388
MVPSKRQLSFQEAGQRAPAGSSLAPPPPQQPGARVGGGGGRAPGLASPRPAGGAVPRRGGAGPGSPVPHSISGTRGWWRHRRWDRGRTRM
GPRGAASLPRGPGPRRLLLPVVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLC
TPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERC
TLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVS
LMDEAVGNVTAALKSSGLWNNTVFIFSTGALKKSLTAKQVQADFITLGLSEEKATYFSEKWKQNAPTLARWAIGQTLMINQLIDMEWKFG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARSB-COMMD7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARSB-COMMD7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARSB-COMMD7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARSBC0026709Mucopolysaccharidosis VI15CTD_human;GENOMICS_ENGLAND;UNIPROT