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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:OPRM1-SCN3A (FusionGDB2 ID:HG4988TG6328)

Fusion Gene Summary for OPRM1-SCN3A

Fusion gene summary

Fusion gene information	Fusion gene name: OPRM1-SCN3A
	Fusion gene ID: hg4988tg6328
		Hgene	Tgene
	Gene symbol	OPRM1	SCN3A
	Gene ID	4988	6328
	Gene name	opioid receptor mu 1	sodium voltage-gated channel alpha subunit 3
	Synonyms	LMOR\|M-OR-1\|MOP\|MOR\|MOR1\|OPRM	EIEE62\|FFEVF4\|NAC3\|Nav1.3
	Cytomap	('OPRM1')('SCN3A') 6q25.2	2q24.3
	Type of gene	protein-coding	protein-coding
	Description	mu-type opioid receptormu opiate receptormu opioid receptor hMOR-1a	sodium channel protein type 3 subunit alphabrain III voltage-gated sodium channelsodium channel protein brain III subunit alphasodium channel protein type III subunit alphasodium channel, voltage gated, type III alpha subunitsodium channel, voltage-g
	Modification date	20200322	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000229768, ENST00000330432, ENST00000337049, ENST00000360422, ENST00000414028, ENST00000419506, ENST00000428397, ENST00000434900, ENST00000435918, ENST00000452687, ENST00000518759, ENST00000520708, ENST00000522236, ENST00000522555, ENST00000523520, ENST00000524163,
Fusion gene scores	* DoF score	11 X 4 X 2=88	6 X 7 X 6=252
	# samples	10	8
	** MAII score	log2(10/88*10)=0.184424571137427 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(8/252*10)=-1.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: OPRM1 [Title/Abstract] AND SCN3A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	OPRM1(154424051)-SCN3A(165978090), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	CB048832	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+

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Fusion Gene ORF analysis for OPRM1-SCN3A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-intron	ENST00000229768	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000229768	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000229768	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000229768	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000229768	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000330432	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000330432	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000330432	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000330432	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000330432	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000337049	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000337049	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000337049	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000337049	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000337049	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000360422	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000360422	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000360422	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000360422	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000360422	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000414028	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000414028	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000414028	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000414028	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000414028	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000419506	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000419506	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000419506	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000419506	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000419506	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000428397	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000428397	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000428397	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000428397	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000428397	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000434900	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000434900	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000434900	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000434900	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000434900	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000435918	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000435918	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000435918	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000435918	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000435918	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000452687	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000452687	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000452687	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000452687	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000452687	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000518759	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000518759	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000518759	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000518759	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000518759	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000520708	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000520708	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000520708	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000520708	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000520708	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522236	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522236	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522236	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522236	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522236	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522555	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522555	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522555	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522555	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000522555	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000523520	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000523520	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000523520	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000523520	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000523520	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000524163	ENST00000283254	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000524163	ENST00000360093	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000524163	ENST00000409101	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000524163	ENST00000465043	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+
intron-intron	ENST00000524163	ENST00000540861	OPRM1	chr6	154424051	-	SCN3A	chr2	165978090	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for OPRM1-SCN3A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

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Fusion Protein Features for OPRM1-SCN3A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:154424051/:165978090)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for OPRM1-SCN3A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for OPRM1-SCN3A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for OPRM1-SCN3A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for OPRM1-SCN3A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	OPRM1	C0001973	Alcoholic Intoxication, Chronic	6	CTD_human;PSYGENET
Hgene	OPRM1	C0600427	Cocaine Dependence	6	CTD_human;PSYGENET
Hgene	OPRM1	C0001969	Alcoholic Intoxication	5	PSYGENET
Hgene	OPRM1	C0011570	Mental Depression	4	PSYGENET
Hgene	OPRM1	C0011581	Depressive disorder	4	PSYGENET
Hgene	OPRM1	C0009171	Cocaine Abuse	3	CTD_human
Hgene	OPRM1	C0036341	Schizophrenia	3	PSYGENET
Hgene	OPRM1	C0085762	Alcohol abuse	3	CTD_human;PSYGENET
Hgene	OPRM1	C0236736	Cocaine-Related Disorders	3	CTD_human
Hgene	OPRM1	C0019196	Hepatitis C	2	CTD_human
Hgene	OPRM1	C0022333	Jacksonian Seizure	2	CTD_human
Hgene	OPRM1	C0027796	Neuralgia	2	CTD_human
Hgene	OPRM1	C0033975	Psychotic Disorders	2	PSYGENET
Hgene	OPRM1	C0036572	Seizures	2	CTD_human
Hgene	OPRM1	C0038870	Neuralgia, Supraorbital	2	CTD_human
Hgene	OPRM1	C0042656	Neuralgia, Vidian	2	CTD_human
Hgene	OPRM1	C0149958	Complex partial seizures	2	CTD_human
Hgene	OPRM1	C0234247	Neuralgia, Atypical	2	CTD_human
Hgene	OPRM1	C0234249	Neuralgia, Stump	2	CTD_human
Hgene	OPRM1	C0234533	Generalized seizures	2	CTD_human
Hgene	OPRM1	C0234535	Clonic Seizures	2	CTD_human
Hgene	OPRM1	C0270824	Visual seizure	2	CTD_human
Hgene	OPRM1	C0270844	Tonic Seizures	2	CTD_human
Hgene	OPRM1	C0270846	Epileptic drop attack	2	CTD_human
Hgene	OPRM1	C0349204	Nonorganic psychosis	2	PSYGENET
Hgene	OPRM1	C0422850	Seizures, Somatosensory	2	CTD_human
Hgene	OPRM1	C0422852	Seizures, Auditory	2	CTD_human
Hgene	OPRM1	C0422853	Olfactory seizure	2	CTD_human
Hgene	OPRM1	C0422854	Gustatory seizure	2	CTD_human
Hgene	OPRM1	C0422855	Vertiginous seizure	2	CTD_human
Hgene	OPRM1	C0423711	Neuralgia, Perineal	2	CTD_human
Hgene	OPRM1	C0423712	Neuralgia, Iliohypogastric Nerve	2	CTD_human
Hgene	OPRM1	C0494475	Tonic - clonic seizures	2	CTD_human
Hgene	OPRM1	C0751056	Non-epileptic convulsion	2	CTD_human
Hgene	OPRM1	C0751110	Single Seizure	2	CTD_human
Hgene	OPRM1	C0751123	Atonic Absence Seizures	2	CTD_human
Hgene	OPRM1	C0751371	Neuralgia, Ilioinguinal	2	CTD_human
Hgene	OPRM1	C0751372	Nerve Pain	2	CTD_human
Hgene	OPRM1	C0751373	Paroxysmal Nerve Pain	2	CTD_human
Hgene	OPRM1	C0751494	Convulsive Seizures	2	CTD_human
Hgene	OPRM1	C0751495	Seizures, Focal	2	CTD_human
Hgene	OPRM1	C0751496	Seizures, Sensory	2	CTD_human
Hgene	OPRM1	C3495874	Nonepileptic Seizures	2	CTD_human
Hgene	OPRM1	C4048158	Convulsions	2	CTD_human
Hgene	OPRM1	C4316903	Absence Seizures	2	CTD_human
Hgene	OPRM1	C4317109	Epileptic Seizures	2	CTD_human
Hgene	OPRM1	C4317123	Myoclonic Seizures	2	CTD_human
Hgene	OPRM1	C4505436	Generalized Absence Seizures	2	CTD_human
Hgene	OPRM1	C0001849	AIDS Dementia Complex	1	CTD_human
Hgene	OPRM1	C0001956	Alcohol Use Disorder	1	CTD_human
Hgene	OPRM1	C0009806	Constipation	1	CTD_human
Hgene	OPRM1	C0013146	Drug abuse	1	CTD_human
Hgene	OPRM1	C0013170	Drug habituation	1	CTD_human
Hgene	OPRM1	C0013222	Drug Use Disorders	1	CTD_human
Hgene	OPRM1	C0013384	Dyskinetic syndrome	1	CTD_human
Hgene	OPRM1	C0014544	Epilepsy	1	CTD_human
Hgene	OPRM1	C0019147	Hepatic Coma	1	CTD_human
Hgene	OPRM1	C0019151	Hepatic Encephalopathy	1	CTD_human
Hgene	OPRM1	C0019337	Heroin Dependence	1	CTD_human
Hgene	OPRM1	C0020429	Hyperalgesia	1	CTD_human
Hgene	OPRM1	C0020651	Hypotension, Orthostatic	1	CTD_human
Hgene	OPRM1	C0026552	Morphine Dependence	1	CTD_human
Hgene	OPRM1	C0026650	Movement Disorders	1	CTD_human
Hgene	OPRM1	C0027497	Nausea	1	CTD_human
Hgene	OPRM1	C0029231	Organic Mental Disorders, Substance-Induced	1	CTD_human
Hgene	OPRM1	C0033774	Pruritus	1	CTD_human
Hgene	OPRM1	C0033937	Psychoses, Drug	1	CTD_human
Hgene	OPRM1	C0033941	Psychoses, Substance-Induced	1	CTD_human
Hgene	OPRM1	C0035229	Respiratory Insufficiency	1	CTD_human
Hgene	OPRM1	C0038580	Substance Dependence	1	CTD_human
Hgene	OPRM1	C0038586	Substance Use Disorders	1	CTD_human
Hgene	OPRM1	C0086237	Epilepsy, Cryptogenic	1	CTD_human
Hgene	OPRM1	C0152115	Lingual-Facial-Buccal Dyskinesia	1	CTD_human
Hgene	OPRM1	C0206019	HIV Encephalopathy	1	CTD_human
Hgene	OPRM1	C0221074	Depression, Postpartum	1	PSYGENET
Hgene	OPRM1	C0221169	Hemiballismus	1	CTD_human
Hgene	OPRM1	C0232766	Asterixis	1	CTD_human
Hgene	OPRM1	C0233477	Dysphoric mood	1	PSYGENET
Hgene	OPRM1	C0235063	Respiratory Depression	1	CTD_human
Hgene	OPRM1	C0236018	Aura	1	CTD_human
Hgene	OPRM1	C0236733	Amphetamine-Related Disorders	1	CTD_human
Hgene	OPRM1	C0236804	Amphetamine Addiction	1	CTD_human
Hgene	OPRM1	C0236807	Amphetamine Abuse	1	CTD_human
Hgene	OPRM1	C0236969	Substance-Related Disorders	1	CTD_human
Hgene	OPRM1	C0237326	Dyschezia	1	CTD_human
Hgene	OPRM1	C0243010	Viral Encephalitis	1	CTD_human
Hgene	OPRM1	C0266487	Etat Marbre	1	CTD_human
Hgene	OPRM1	C0427086	Involuntary Movements	1	CTD_human
Hgene	OPRM1	C0454606	Oral Dyskinesia	1	CTD_human
Hgene	OPRM1	C0458247	Allodynia	1	CTD_human
Hgene	OPRM1	C0600241	heroin abuse	1	CTD_human
Hgene	OPRM1	C0600272	Morphine Abuse	1	CTD_human
Hgene	OPRM1	C0740858	Substance abuse problem	1	CTD_human
Hgene	OPRM1	C0751111	Awakening Epilepsy	1	CTD_human
Hgene	OPRM1	C0751197	Fulminant Hepatic Failure with Cerebral Edema	1	CTD_human
Hgene	OPRM1	C0751198	Hepatic Stupor	1	CTD_human
Hgene	OPRM1	C0751211	Hyperalgesia, Primary	1	CTD_human
Hgene	OPRM1	C0751212	Hyperalgesia, Secondary	1	CTD_human
Hgene	OPRM1	C0751213	Tactile Allodynia	1	CTD_human
Hgene	OPRM1	C0751214	Hyperalgesia, Thermal	1	CTD_human
Hgene	OPRM1	C0752196	Ballismus	1	CTD_human
Hgene	OPRM1	C0936243	HIV-1-Associated Cognitive Motor Complex	1	CTD_human
Hgene	OPRM1	C1145670	Respiratory Failure	1	CTD_human
Hgene	OPRM1	C1257861	Colonic Inertia	1	CTD_human
Hgene	OPRM1	C1510472	Drug Dependence	1	CTD_human
Hgene	OPRM1	C1837893	SCHIZOPHRENIA 12	1	PSYGENET
Hgene	OPRM1	C2936719	Mechanical Allodynia	1	CTD_human
Hgene	OPRM1	C4316881	Prescription Drug Abuse	1	CTD_human
Hgene	OPRM1	C4505390	Heroin Smoking	1	CTD_human
Tgene		C4693694	EPILEPSY, FAMILIAL FOCAL, WITH VARIABLE FOCI 4	2	GENOMICS_ENGLAND;UNIPROT
Tgene		C4693699	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 62	2	GENOMICS_ENGLAND;UNIPROT
Tgene		C0014547	Epilepsies, Partial	1	GENOMICS_ENGLAND
Tgene		C0085417	Epilepsy, Complex Partial	1	CTD_human
Tgene		C0751640	Cryptogenic Partial Complex Epilepsy	1	CTD_human
Tgene		C0751641	Epilepsy, Symptomatic, Partial Complex	1	CTD_human
Tgene		C3714756	Intellectual Disability	1	GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:OPRM1-SCN3A (FusionGDB2 ID:HG4988TG6328)

Fusion Gene Summary for OPRM1-SCN3A

Fusion Gene ORF analysis for OPRM1-SCN3A

Fusion Genomic Features for OPRM1-SCN3A

Fusion Protein Features for OPRM1-SCN3A

Fusion Gene Sequence for OPRM1-SCN3A

Fusion Gene PPI Analysis for OPRM1-SCN3A

Related Drugs for OPRM1-SCN3A

Related Diseases for OPRM1-SCN3A

Fusion Gene Studies
in Kim Lab