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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DDX27-PTPRF (FusionGDB2 ID:HG55661TG5792)

Fusion Gene Summary for DDX27-PTPRF

check button Fusion gene summary
Fusion gene informationFusion gene name: DDX27-PTPRF
Fusion gene ID: hg55661tg5792
HgeneTgene
Gene symbol

DDX27

PTPRF

Gene ID

55661

5792

Gene nameDEAD-box helicase 27protein tyrosine phosphatase receptor type F
SynonymsDRS1|Drs1p|HSPC259|PP3241|RHLP|dJ686N3.1BNAH2|LAR
Cytomap('DDX27')('PTPRF')

20q13.13

1p34.2

Type of geneprotein-codingprotein-coding
Descriptionprobable ATP-dependent RNA helicase DDX27DEAD (Asp-Glu-Ala-Asp) box polypeptide 27DEAD box protein 27DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 27Deficiency of ribosomal subunits protein 1 homologRNA helicase-like proteinreceptor-type tyrosine-protein phosphatase FLCA-homologleukocyte antigen-related (LAR) PTP receptorleukocyte antigen-related tyrosine phosphataseleukocyte common antigen relatedprotein tyrosine phosphatase, receptor type, F polypeptidereceptor-linke
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000484427, ENST00000371764, 
Fusion gene scores* DoF score8 X 8 X 5=32010 X 14 X 6=840
# samples 815
** MAII scorelog2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/840*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DDX27 [Title/Abstract] AND PTPRF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDDX27(47841528)-PTPRF(44086124), # samples:1
Anticipated loss of major functional domain due to fusion event.DDX27-PTPRF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DDX27-PTPRF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DDX27-PTPRF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DDX27-PTPRF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePTPRF

GO:0099560

synaptic membrane adhesion

26321637


check buttonFusion gene breakpoints across DDX27 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PTPRF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4IYDDX27chr20

47841528

+PTPRFchr1

44086124

+


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Fusion Gene ORF analysis for DDX27-PTPRF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000484427ENST00000359947DDX27chr20

47841528

+PTPRFchr1

44086124

+
3UTR-3CDSENST00000484427ENST00000372413DDX27chr20

47841528

+PTPRFchr1

44086124

+
3UTR-3CDSENST00000484427ENST00000372414DDX27chr20

47841528

+PTPRFchr1

44086124

+
3UTR-3CDSENST00000484427ENST00000422171DDX27chr20

47841528

+PTPRFchr1

44086124

+
3UTR-3CDSENST00000484427ENST00000438120DDX27chr20

47841528

+PTPRFchr1

44086124

+
3UTR-3UTRENST00000484427ENST00000496447DDX27chr20

47841528

+PTPRFchr1

44086124

+
5CDS-3UTRENST00000371764ENST00000496447DDX27chr20

47841528

+PTPRFchr1

44086124

+
In-frameENST00000371764ENST00000359947DDX27chr20

47841528

+PTPRFchr1

44086124

+
In-frameENST00000371764ENST00000372413DDX27chr20

47841528

+PTPRFchr1

44086124

+
In-frameENST00000371764ENST00000372414DDX27chr20

47841528

+PTPRFchr1

44086124

+
In-frameENST00000371764ENST00000422171DDX27chr20

47841528

+PTPRFchr1

44086124

+
In-frameENST00000371764ENST00000438120DDX27chr20

47841528

+PTPRFchr1

44086124

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371764DDX27chr2047841528+ENST00000359947PTPRFchr144086124+276461591100363
ENST00000371764DDX27chr2047841528+ENST00000438120PTPRFchr144086124+145561591100363
ENST00000371764DDX27chr2047841528+ENST00000372413PTPRFchr144086124+277061591100363
ENST00000371764DDX27chr2047841528+ENST00000372414PTPRFchr144086124+277061591100363
ENST00000371764DDX27chr2047841528+ENST00000422171PTPRFchr144086124+194061591100363

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371764ENST00000359947DDX27chr2047841528+PTPRFchr144086124+0.0011300370.99886996
ENST00000371764ENST00000438120DDX27chr2047841528+PTPRFchr144086124+0.0029263030.99707365
ENST00000371764ENST00000372413DDX27chr2047841528+PTPRFchr144086124+0.0011334650.99886656
ENST00000371764ENST00000372414DDX27chr2047841528+PTPRFchr144086124+0.0011334650.99886656
ENST00000371764ENST00000422171DDX27chr2047841528+PTPRFchr144086124+0.0017380580.998262

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Fusion Genomic Features for DDX27-PTPRF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DDX27chr2047841528+PTPRFchr144086124+0.0001131670.9998869
DDX27chr2047841528+PTPRFchr144086124+0.0001131670.9998869

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DDX27-PTPRF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:47841528/chr1:44086124)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+52144_200202797.0Compositional biasNote=Asp/Glu/Lys-rich
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521195_200202797.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521249_423202797.0DomainHelicase ATP-binding
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521457_603202797.0DomainHelicase C-terminal
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521218_246202797.0MotifNote=Q motif
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521371_374202797.0MotifNote=DEAD box
HgeneDDX27chr20:47841528chr1:44086124ENST00000371764+521262_269202797.0Nucleotide bindingATP
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341014_109817461908.0DomainFibronectin type-III 8
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341352_160717461908.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934135_22417461908.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341639_189817461908.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934232_31417461908.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934321_41117461908.0DomainFibronectin type-III 1
TgenePTPRFchr20:47841528chr1:44086124ENST00000359947293433_12317461908.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934416_51017461908.0DomainFibronectin type-III 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934514_60417461908.0DomainFibronectin type-III 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934609_70617461908.0DomainFibronectin type-III 4
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934711_81917461908.0DomainFibronectin type-III 5
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934820_91417461908.0DomainFibronectin type-III 6
TgenePTPRFchr20:47841528chr1:44086124ENST000003599472934918_101017461908.0DomainFibronectin type-III 7
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311014_109817371899.0DomainFibronectin type-III 8
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311352_160717371899.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631135_22417371899.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311639_189817371899.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631232_31417371899.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631321_41117371899.0DomainFibronectin type-III 1
TgenePTPRFchr20:47841528chr1:44086124ENST00000372413263133_12317371899.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631416_51017371899.0DomainFibronectin type-III 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631514_60417371899.0DomainFibronectin type-III 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631609_70617371899.0DomainFibronectin type-III 4
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631711_81917371899.0DomainFibronectin type-III 5
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631820_91417371899.0DomainFibronectin type-III 6
TgenePTPRFchr20:47841528chr1:44086124ENST000003724132631918_101017371899.0DomainFibronectin type-III 7
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321014_109817461908.0DomainFibronectin type-III 8
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321352_160717461908.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732135_22417461908.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321639_189817461908.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732232_31417461908.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732321_41117461908.0DomainFibronectin type-III 1
TgenePTPRFchr20:47841528chr1:44086124ENST00000372414273233_12317461908.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732416_51017461908.0DomainFibronectin type-III 2
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732514_60417461908.0DomainFibronectin type-III 3
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732609_70617461908.0DomainFibronectin type-III 4
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732711_81917461908.0DomainFibronectin type-III 5
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732820_91417461908.0DomainFibronectin type-III 6
TgenePTPRFchr20:47841528chr1:44086124ENST000003724142732918_101017461908.0DomainFibronectin type-III 7
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331014_109817371899.0DomainFibronectin type-III 8
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331352_160717371899.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833135_22417371899.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331639_189817371899.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833232_31417371899.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833321_41117371899.0DomainFibronectin type-III 1
TgenePTPRFchr20:47841528chr1:44086124ENST00000438120283333_12317371899.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833416_51017371899.0DomainFibronectin type-III 2
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833514_60417371899.0DomainFibronectin type-III 3
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833609_70617371899.0DomainFibronectin type-III 4
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833711_81917371899.0DomainFibronectin type-III 5
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833820_91417371899.0DomainFibronectin type-III 6
TgenePTPRFchr20:47841528chr1:44086124ENST000004381202833918_101017371899.0DomainFibronectin type-III 7
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341548_155417461908.0RegionSubstrate binding
TgenePTPRFchr20:47841528chr1:44086124ENST00000359947293468_7717461908.0RegionHeparin-binding
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311548_155417371899.0RegionSubstrate binding
TgenePTPRFchr20:47841528chr1:44086124ENST00000372413263168_7717371899.0RegionHeparin-binding
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321548_155417461908.0RegionSubstrate binding
TgenePTPRFchr20:47841528chr1:44086124ENST00000372414273268_7717461908.0RegionHeparin-binding
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331548_155417371899.0RegionSubstrate binding
TgenePTPRFchr20:47841528chr1:44086124ENST00000438120283368_7717371899.0RegionHeparin-binding
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341285_190717461908.0Topological domainCytoplasmic
TgenePTPRFchr20:47841528chr1:44086124ENST00000359947293430_126317461908.0Topological domainExtracellular
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311285_190717371899.0Topological domainCytoplasmic
TgenePTPRFchr20:47841528chr1:44086124ENST00000372413263130_126317371899.0Topological domainExtracellular
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321285_190717461908.0Topological domainCytoplasmic
TgenePTPRFchr20:47841528chr1:44086124ENST00000372414273230_126317461908.0Topological domainExtracellular
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331285_190717371899.0Topological domainCytoplasmic
TgenePTPRFchr20:47841528chr1:44086124ENST00000438120283330_126317371899.0Topological domainExtracellular
TgenePTPRFchr20:47841528chr1:44086124ENST0000035994729341264_128417461908.0TransmembraneHelical
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241326311264_128417371899.0TransmembraneHelical
TgenePTPRFchr20:47841528chr1:44086124ENST0000037241427321264_128417461908.0TransmembraneHelical
TgenePTPRFchr20:47841528chr1:44086124ENST0000043812028331264_128417371899.0TransmembraneHelical


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Fusion Gene Sequence for DDX27-PTPRF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21962_21962_1_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000359947_length(transcript)=2764nt_BP=615nt
AAGTGACGCATGGTACTTGCGCAAAGACGACGAGGAGGCTGCGAAAAGTTAAGGGCCGGACCGCAGGCTGTGCTCGCTTCCGGAAGTGGC
TTCTGCGACAACATGCTTGCGGACCTCGGCTTAATCGGAACCATAGGCGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGG
GACGAGGAAGAGGAGGGGCCCATTGTGCTGGGCAGACGACAAAAAGCTTTGGGGAAGAACCGCAGTGCTGATTTCAACCCTGATTTCGTT
TTCACTGAGAAGGAGGGGACGTACGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCAACTCAAGAAGAAGAGGGCAGCCACTACATTA
GATGAGAAGATTGAGAAAGTTCGAAAGAAAAGGAAAACAGAGGATAAAGAAGCCAAGTCTGGGAAGTTGGAAAAGGAGAAAGAAGCAAAG
GAAGGCTCTGAACCAAAGGAGCAGGAAGACCTTCAAGAGAATGATGAGGAAGGCTCAGAAGATGAAGCCTCGGAGACTGACTACTCATCA
GCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAGGATCGGAAGAAGAAGAAGAAGAAAGGACAGGAGAAATGCCACCAG
TACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATCCTGCGTGAG
TTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTGCCCAAGACA
GGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCACTGCAGTGCT
GGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTTCAGACCGTG
AAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTACCTCGGCAGC
TTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCTCTGAGCCAT
ACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACGTTGCCACAC
CAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCACCTGGAGCC
CGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAATACATTAAG
TGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAGGGGTTGGGG
TTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATTGCCTTCCTC
GTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCCCTTCAGACG
AGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCACATTGACAGT
GGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCACAGATGTGTC
TGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAAAACAAAAAA
AACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTGCCTGGGGTT
CCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAGGCTGTGGGG
TCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTGGCTGGCCTT
TCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGCTGTTTTCAA
AGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGTACTCTAATC
AGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGGGCGGGGAAG
GGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGGGTTGGTAAT
GTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATTTGTTAAGAA

>21962_21962_1_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000359947_length(amino acids)=363AA_BP=201
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTE
KEGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
NILTKADTLKVKDRKKKKKKGQEKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEG
FIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH

--------------------------------------------------------------
>21962_21962_2_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000372413_length(transcript)=2770nt_BP=615nt
AAGTGACGCATGGTACTTGCGCAAAGACGACGAGGAGGCTGCGAAAAGTTAAGGGCCGGACCGCAGGCTGTGCTCGCTTCCGGAAGTGGC
TTCTGCGACAACATGCTTGCGGACCTCGGCTTAATCGGAACCATAGGCGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGG
GACGAGGAAGAGGAGGGGCCCATTGTGCTGGGCAGACGACAAAAAGCTTTGGGGAAGAACCGCAGTGCTGATTTCAACCCTGATTTCGTT
TTCACTGAGAAGGAGGGGACGTACGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCAACTCAAGAAGAAGAGGGCAGCCACTACATTA
GATGAGAAGATTGAGAAAGTTCGAAAGAAAAGGAAAACAGAGGATAAAGAAGCCAAGTCTGGGAAGTTGGAAAAGGAGAAAGAAGCAAAG
GAAGGCTCTGAACCAAAGGAGCAGGAAGACCTTCAAGAGAATGATGAGGAAGGCTCAGAAGATGAAGCCTCGGAGACTGACTACTCATCA
GCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAGGATCGGAAGAAGAAGAAGAAGAAAGGACAGGAGAAATGCCACCAG
TACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATCCTGCGTGAG
TTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTGCCCAAGACA
GGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCACTGCAGTGCT
GGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTTCAGACCGTG
AAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTACCTCGGCAGC
TTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCTCTGAGCCAT
ACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACGTTGCCACAC
CAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCACCTGGAGCC
CGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAATACATTAAG
TGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAGGGGTTGGGG
TTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATTGCCTTCCTC
GTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCCCTTCAGACG
AGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCACATTGACAGT
GGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCACAGATGTGTC
TGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAAAACAAAAAA
AACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTGCCTGGGGTT
CCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAGGCTGTGGGG
TCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTGGCTGGCCTT
TCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGCTGTTTTCAA
AGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGTACTCTAATC
AGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGGGCGGGGAAG
GGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGGGTTGGTAAT
GTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATTTGTTAAGAA

>21962_21962_2_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000372413_length(amino acids)=363AA_BP=201
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTE
KEGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
NILTKADTLKVKDRKKKKKKGQEKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEG
FIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH

--------------------------------------------------------------
>21962_21962_3_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000372414_length(transcript)=2770nt_BP=615nt
AAGTGACGCATGGTACTTGCGCAAAGACGACGAGGAGGCTGCGAAAAGTTAAGGGCCGGACCGCAGGCTGTGCTCGCTTCCGGAAGTGGC
TTCTGCGACAACATGCTTGCGGACCTCGGCTTAATCGGAACCATAGGCGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGG
GACGAGGAAGAGGAGGGGCCCATTGTGCTGGGCAGACGACAAAAAGCTTTGGGGAAGAACCGCAGTGCTGATTTCAACCCTGATTTCGTT
TTCACTGAGAAGGAGGGGACGTACGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCAACTCAAGAAGAAGAGGGCAGCCACTACATTA
GATGAGAAGATTGAGAAAGTTCGAAAGAAAAGGAAAACAGAGGATAAAGAAGCCAAGTCTGGGAAGTTGGAAAAGGAGAAAGAAGCAAAG
GAAGGCTCTGAACCAAAGGAGCAGGAAGACCTTCAAGAGAATGATGAGGAAGGCTCAGAAGATGAAGCCTCGGAGACTGACTACTCATCA
GCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAGGATCGGAAGAAGAAGAAGAAGAAAGGACAGGAGAAATGCCACCAG
TACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATCCTGCGTGAG
TTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTGCCCAAGACA
GGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCACTGCAGTGCT
GGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTTCAGACCGTG
AAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTACCTCGGCAGC
TTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCTCTGAGCCAT
ACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACGTTGCCACAC
CAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCACCTGGAGCC
CGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAATACATTAAG
TGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAGGGGTTGGGG
TTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATTGCCTTCCTC
GTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCCCTTCAGACG
AGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCACATTGACAGT
GGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCACAGATGTGTC
TGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAAAACAAAAAA
AACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTGCCTGGGGTT
CCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAGGCTGTGGGG
TCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTGGCTGGCCTT
TCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGCTGTTTTCAA
AGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGTACTCTAATC
AGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGGGCGGGGAAG
GGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGGGTTGGTAAT
GTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATTTGTTAAGAA

>21962_21962_3_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000372414_length(amino acids)=363AA_BP=201
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTE
KEGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
NILTKADTLKVKDRKKKKKKGQEKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEG
FIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH

--------------------------------------------------------------
>21962_21962_4_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000422171_length(transcript)=1940nt_BP=615nt
AAGTGACGCATGGTACTTGCGCAAAGACGACGAGGAGGCTGCGAAAAGTTAAGGGCCGGACCGCAGGCTGTGCTCGCTTCCGGAAGTGGC
TTCTGCGACAACATGCTTGCGGACCTCGGCTTAATCGGAACCATAGGCGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGG
GACGAGGAAGAGGAGGGGCCCATTGTGCTGGGCAGACGACAAAAAGCTTTGGGGAAGAACCGCAGTGCTGATTTCAACCCTGATTTCGTT
TTCACTGAGAAGGAGGGGACGTACGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCAACTCAAGAAGAAGAGGGCAGCCACTACATTA
GATGAGAAGATTGAGAAAGTTCGAAAGAAAAGGAAAACAGAGGATAAAGAAGCCAAGTCTGGGAAGTTGGAAAAGGAGAAAGAAGCAAAG
GAAGGCTCTGAACCAAAGGAGCAGGAAGACCTTCAAGAGAATGATGAGGAAGGCTCAGAAGATGAAGCCTCGGAGACTGACTACTCATCA
GCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAGGATCGGAAGAAGAAGAAGAAGAAAGGACAGGAGAAATGCCACCAG
TACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATCCTGCGTGAG
TTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTGCCCAAGACA
GGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCACTGCAGTGCT
GGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTTCAGACCGTG
AAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTACCTCGGCAGC
TTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCTCTGAGCCAT
ACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACGTTGCCACAC
CAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCACCTGGAGCC
CGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAATACATTAAG
TGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAGGGGTTGGGG
TTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATTGCCTTCCTC
GTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCCCTTCAGACG
AGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCACATTGACAGT
GGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCACAGATGTGTC

>21962_21962_4_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000422171_length(amino acids)=363AA_BP=201
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTE
KEGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
NILTKADTLKVKDRKKKKKKGQEKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEG
FIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH

--------------------------------------------------------------
>21962_21962_5_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000438120_length(transcript)=1455nt_BP=615nt
AAGTGACGCATGGTACTTGCGCAAAGACGACGAGGAGGCTGCGAAAAGTTAAGGGCCGGACCGCAGGCTGTGCTCGCTTCCGGAAGTGGC
TTCTGCGACAACATGCTTGCGGACCTCGGCTTAATCGGAACCATAGGCGAGGATGACGAGGTGCCGGTGGAGCCCGAGTCTGACTCCGGG
GACGAGGAAGAGGAGGGGCCCATTGTGCTGGGCAGACGACAAAAAGCTTTGGGGAAGAACCGCAGTGCTGATTTCAACCCTGATTTCGTT
TTCACTGAGAAGGAGGGGACGTACGATGGCAGCTGGGCCCTGGCTGATGTCATGAGCCAACTCAAGAAGAAGAGGGCAGCCACTACATTA
GATGAGAAGATTGAGAAAGTTCGAAAGAAAAGGAAAACAGAGGATAAAGAAGCCAAGTCTGGGAAGTTGGAAAAGGAGAAAGAAGCAAAG
GAAGGCTCTGAACCAAAGGAGCAGGAAGACCTTCAAGAGAATGATGAGGAAGGCTCAGAAGATGAAGCCTCGGAGACTGACTACTCATCA
GCTGATGAGAACATCCTCACCAAAGCAGATACACTCAAAGTAAAGGATCGGAAGAAGAAGAAGAAGAAAGGACAGGAGAAATGCCACCAG
TACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATCCTGCGTGAG
TTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTGCCCAAGACA
GGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCACTGCAGTGCT
GGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTTCAGACCGTG
AAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTACCTCGGCAGC
TTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCTCTGAGCCAT
ACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACGTTGCCACAC
CAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCACCTGGAGCC
CGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAATACATTAAG

>21962_21962_5_DDX27-PTPRF_DDX27_chr20_47841528_ENST00000371764_PTPRF_chr1_44086124_ENST00000438120_length(amino acids)=363AA_BP=201
MVLAQRRRGGCEKLRAGPQAVLASGSGFCDNMLADLGLIGTIGEDDEVPVEPESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTE
KEGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASETDYSSADE
NILTKADTLKVKDRKKKKKKGQEKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEG
FIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DDX27-PTPRF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DDX27-PTPRF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DDX27-PTPRF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0024623Malignant neoplasm of stomach1CTD_human
TgeneC0038356Stomach Neoplasms1CTD_human
TgeneC0175755Congenital absent nipple1GENOMICS_ENGLAND
TgeneC0235874Disease Exacerbation1CTD_human
TgeneC0345967Malignant mesothelioma1CTD_human
TgeneC0432357Congenital absence of breast with absent nipple1ORPHANET
TgeneC1708349Hereditary Diffuse Gastric Cancer1CTD_human