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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PTGS2-SEMG1 (FusionGDB2 ID:HG5743TG6406)

Fusion Gene Summary for PTGS2-SEMG1

check button Fusion gene summary
Fusion gene informationFusion gene name: PTGS2-SEMG1
Fusion gene ID: hg5743tg6406
HgeneTgene
Gene symbol

PTGS2

SEMG1

Gene ID

5743

6406

Gene nameprostaglandin-endoperoxide synthase 2semenogelin 1
SynonymsCOX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2CT103|SEMG|SGI|dJ172H20.2
Cytomap('PTGS2')('SEMG1')

1q31.1

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionprostaglandin G/H synthase 2PGH synthase 2PHS IIcyclooxygenase 2cyclooxygenase 2bprostaglandin H2 synthase 2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)semenogelin-1SgI-29cancer/testis antigen 103semen coagulating proteinsemenogelin I
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000367468, ENST00000490885, 
Fusion gene scores* DoF score2 X 2 X 2=85 X 5 X 2=50
# samples 24
** MAII scorelog2(2/8*10)=1.32192809488736log2(4/50*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTGS2 [Title/Abstract] AND SEMG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPTGS2(186648554)-SEMG1(43836884), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTGS2

GO:0019371

cyclooxygenase pathway

1380156

TgeneSEMG1

GO:0019731

antibacterial humoral response

18714013

TgeneSEMG1

GO:0031640

killing of cells of other organism

18314226

TgeneSEMG1

GO:0050817

coagulation

8665956

TgeneSEMG1

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

18314226

TgeneSEMG1

GO:0090281

negative regulation of calcium ion import

22075473

TgeneSEMG1

GO:1901318

negative regulation of flagellated sperm motility

22075473



check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-8258-11APTGS2chr1

186648554

+SEMG1chr20

43836884

+


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Fusion Gene ORF analysis for PTGS2-SEMG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-intronENST00000367468ENST00000244069PTGS2chr1

186648554

+SEMG1chr20

43836884

+
intron-intronENST00000367468ENST00000372781PTGS2chr1

186648554

+SEMG1chr20

43836884

+
intron-intronENST00000490885ENST00000244069PTGS2chr1

186648554

+SEMG1chr20

43836884

+
intron-intronENST00000490885ENST00000372781PTGS2chr1

186648554

+SEMG1chr20

43836884

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for PTGS2-SEMG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


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Fusion Protein Features for PTGS2-SEMG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:186648554/:43836884)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for PTGS2-SEMG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for PTGS2-SEMG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PTGS2-SEMG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PTGS2-SEMG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePTGS2C0005684Malignant neoplasm of urinary bladder7CTD_human
HgenePTGS2C0005695Bladder Neoplasm7CTD_human
HgenePTGS2C0009402Colorectal Carcinoma6CTD_human
HgenePTGS2C0009404Colorectal Neoplasms6CTD_human
HgenePTGS2C0011581Depressive disorder6CTD_human;PSYGENET
HgenePTGS2C0035126Reperfusion Injury6CTD_human
HgenePTGS2C0006142Malignant neoplasm of breast5CTD_human
HgenePTGS2C0011570Mental Depression5PSYGENET
HgenePTGS2C0033578Prostatic Neoplasms5CTD_human
HgenePTGS2C0038358Gastric ulcer5CTD_human
HgenePTGS2C0376358Malignant neoplasm of prostate5CTD_human
HgenePTGS2C0678222Breast Carcinoma5CTD_human
HgenePTGS2C1257931Mammary Neoplasms, Human5CTD_human
HgenePTGS2C1458155Mammary Neoplasms5CTD_human
HgenePTGS2C2239176Liver carcinoma5CTD_human
HgenePTGS2C4704874Mammary Carcinoma, Human5CTD_human
HgenePTGS2C0007138Carcinoma, Transitional Cell4CTD_human
HgenePTGS2C0007786Brain Ischemia4CTD_human
HgenePTGS2C0020538Hypertensive disease4CTD_human
HgenePTGS2C0024623Malignant neoplasm of stomach4CTD_human
HgenePTGS2C0030297Pancreatic Neoplasm4CTD_human
HgenePTGS2C0036341Schizophrenia4PSYGENET
HgenePTGS2C0038356Stomach Neoplasms4CTD_human
HgenePTGS2C0346647Malignant neoplasm of pancreas4CTD_human
HgenePTGS2C0917798Cerebral Ischemia4CTD_human
HgenePTGS2C1708349Hereditary Diffuse Gastric Cancer4CTD_human
HgenePTGS2C0004763Barrett Esophagus3CTD_human
HgenePTGS2C0007102Malignant tumor of colon3CTD_human
HgenePTGS2C0007114Malignant neoplasm of skin3CTD_human
HgenePTGS2C0009375Colonic Neoplasms3CTD_human
HgenePTGS2C0014859Esophageal Neoplasms3CTD_human
HgenePTGS2C0020507Hyperplasia3CTD_human
HgenePTGS2C0021368Inflammation3CTD_human
HgenePTGS2C0021846Intestinal Polyps3CTD_human
HgenePTGS2C0025202melanoma3CTD_human
HgenePTGS2C0037286Skin Neoplasms3CTD_human
HgenePTGS2C0041696Unipolar Depression3CTD_human;PSYGENET
HgenePTGS2C0279626Squamous cell carcinoma of esophagus3CTD_human
HgenePTGS2C0546837Malignant neoplasm of esophagus3CTD_human
HgenePTGS2C1258085Barrett Epithelium3CTD_human
HgenePTGS2C0001418Adenocarcinoma2CTD_human
HgenePTGS2C0002152Alloxan Diabetes2CTD_human
HgenePTGS2C0002736Amyotrophic Lateral Sclerosis2CTD_human
HgenePTGS2C0003873Rheumatoid Arthritis2CTD_human
HgenePTGS2C0007137Squamous cell carcinoma2CTD_human
HgenePTGS2C0011853Diabetes Mellitus, Experimental2CTD_human
HgenePTGS2C0020429Hyperalgesia2CTD_human
HgenePTGS2C0023893Liver Cirrhosis, Experimental2CTD_human
HgenePTGS2C0027627Neoplasm Metastasis2CTD_human
HgenePTGS2C0030354Papilloma2CTD_human
HgenePTGS2C0032927Precancerous Conditions2CTD_human
HgenePTGS2C0038433Streptozotocin Diabetes2CTD_human
HgenePTGS2C0040411Tongue Neoplasms2CTD_human
HgenePTGS2C0151526Premature Birth2CTD_human
HgenePTGS2C0153349Malignant neoplasm of tongue2CTD_human
HgenePTGS2C0205641Adenocarcinoma, Basal Cell2CTD_human
HgenePTGS2C0205642Adenocarcinoma, Oxyphilic2CTD_human
HgenePTGS2C0205643Carcinoma, Cribriform2CTD_human
HgenePTGS2C0205644Carcinoma, Granular Cell2CTD_human
HgenePTGS2C0205645Adenocarcinoma, Tubular2CTD_human
HgenePTGS2C0205874Papilloma, Squamous Cell2CTD_human
HgenePTGS2C0205875Papillomatosis2CTD_human
HgenePTGS2C0282313Condition, Preneoplastic2CTD_human
HgenePTGS2C0393554Amyotrophic Lateral Sclerosis With Dementia2CTD_human
HgenePTGS2C0458247Allodynia2CTD_human
HgenePTGS2C0543859Amyotrophic Lateral Sclerosis, Guam Form2CTD_human
HgenePTGS2C0751211Hyperalgesia, Primary2CTD_human
HgenePTGS2C0751212Hyperalgesia, Secondary2CTD_human
HgenePTGS2C0751213Tactile Allodynia2CTD_human
HgenePTGS2C0751214Hyperalgesia, Thermal2CTD_human
HgenePTGS2C0878500Intraepithelial Neoplasia2CTD_human
HgenePTGS2C1269683Major Depressive Disorder2PSYGENET
HgenePTGS2C1319853Asthma, Aspirin-Induced2CTD_human
HgenePTGS2C2936719Mechanical Allodynia2CTD_human
HgenePTGS2C0001624Adrenal Gland Neoplasms1CTD_human
HgenePTGS2C0001925Albuminuria1CTD_human
HgenePTGS2C0003811Cardiac Arrhythmia1CTD_human
HgenePTGS2C0004045Asphyxia Neonatorum1CTD_human
HgenePTGS2C0004153Atherosclerosis1CTD_human
HgenePTGS2C0004352Autistic Disorder1CTD_human
HgenePTGS2C0005694Bladder neck obstruction1CTD_human
HgenePTGS2C0005967Bone neoplasms1CTD_human
HgenePTGS2C0006625Cachexia1CTD_human
HgenePTGS2C0006826Malignant Neoplasms1CTD_human
HgenePTGS2C0007097Carcinoma1CTD_human
HgenePTGS2C0007134Renal Cell Carcinoma1CTD_human
HgenePTGS2C0007222Cardiovascular Diseases1CTD_human
HgenePTGS2C0009241Cognition Disorders1CTD_human
HgenePTGS2C0009319Colitis1CTD_human
HgenePTGS2C0010054Coronary Arteriosclerosis1CTD_human
HgenePTGS2C0010474Curling Ulcer1CTD_human
HgenePTGS2C0011573Endogenous depression1CTD_human
HgenePTGS2C0011849Diabetes Mellitus1CTD_human
HgenePTGS2C0013221Drug toxicity1CTD_human
HgenePTGS2C0013295Duodenal Ulcer1CTD_human
HgenePTGS2C0013604Edema1CTD_human
HgenePTGS2C0014175Endometriosis1CTD_human
HgenePTGS2C0015967Fever1CTD_human
HgenePTGS2C0016059Fibrosis1CTD_human
HgenePTGS2C0017168Gastroesophageal reflux disease1CTD_human
HgenePTGS2C0017612Glaucoma, Open-Angle1CTD_human
HgenePTGS2C0017638Glioma1CTD_human
HgenePTGS2C0018801Heart failure1CTD_human
HgenePTGS2C0018802Congestive heart failure1CTD_human
HgenePTGS2C0019064Hemopericardium1CTD_human
HgenePTGS2C0019193Hepatitis, Toxic1CTD_human
HgenePTGS2C0020295Hydronephrosis1CTD_human
HgenePTGS2C0020452Hyperemia1CTD_human
HgenePTGS2C0020456Hyperglycemia1CTD_human
HgenePTGS2C0021367Mammary Ductal Carcinoma1CTD_human
HgenePTGS2C0021390Inflammatory Bowel Diseases1CTD_human
HgenePTGS2C0022333Jacksonian Seizure1CTD_human
HgenePTGS2C0022658Kidney Diseases1CTD_human
HgenePTGS2C0022661Kidney Failure, Chronic1CTD_human
HgenePTGS2C0022665Kidney Neoplasm1CTD_human
HgenePTGS2C0023212Left-Sided Heart Failure1CTD_human
HgenePTGS2C0023269leiomyosarcoma1CTD_human
HgenePTGS2C0023434Chronic Lymphocytic Leukemia1CTD_human
HgenePTGS2C0023532Leukoplakia, Oral1CTD_human
HgenePTGS2C0024115Lung diseases1CTD_human
HgenePTGS2C0024141Lupus Erythematosus, Systemic1CTD_human
HgenePTGS2C0024809Marijuana Abuse1PSYGENET
HgenePTGS2C0025193Melancholia1CTD_human
HgenePTGS2C0026636Mouth Diseases1CTD_human
HgenePTGS2C0026640Mouth Neoplasms1CTD_human
HgenePTGS2C0027643Neoplasm Recurrence, Local1CTD_human
HgenePTGS2C0027651Neoplasms1CTD_human
HgenePTGS2C0027765nervous system disorder1CTD_human
HgenePTGS2C0028754Obesity1CTD_human
HgenePTGS2C0029172Oral Submucous Fibrosis1CTD_human
HgenePTGS2C0030305Pancreatitis1CTD_human
HgenePTGS2C0031039Pericardial effusion1CTD_human
HgenePTGS2C0032580Adenomatous Polyposis Coli1CTD_human
HgenePTGS2C0033141Cardiomyopathies, Primary1CTD_human
HgenePTGS2C0033687Proteinuria1CTD_human
HgenePTGS2C0034013Precocious Puberty1CTD_human
HgenePTGS2C0036529Myocardial Diseases, Secondary1CTD_human
HgenePTGS2C0036572Seizures1CTD_human
HgenePTGS2C0037274Dermatologic disorders1CTD_human
HgenePTGS2C0038220Status Epilepticus1CTD_human
HgenePTGS2C0038454Cerebrovascular accident1CTD_human
HgenePTGS2C0040053Thrombosis1CTD_human
HgenePTGS2C0040136Thyroid Neoplasm1CTD_human
HgenePTGS2C0041755Adverse reaction to drug1CTD_human
HgenePTGS2C0042484Venous Engorgement1CTD_human
HgenePTGS2C0079731B-Cell Lymphomas1CTD_human
HgenePTGS2C0086133Depressive Syndrome1CTD_human
HgenePTGS2C0086692Benign Neoplasm1CTD_human
HgenePTGS2C0087086Thrombus1CTD_human
HgenePTGS2C0149958Complex partial seizures1CTD_human
HgenePTGS2C0151468Thyroid Gland Follicular Adenoma1CTD_human
HgenePTGS2C0151603Anasarca1CTD_human
HgenePTGS2C0153381Malignant neoplasm of mouth1CTD_human
HgenePTGS2C0162871Aortic Aneurysm, Abdominal1CTD_human
HgenePTGS2C0178824Reactive Hyperemia1CTD_human
HgenePTGS2C0205696Anaplastic carcinoma1CTD_human
HgenePTGS2C0205697Carcinoma, Spindle-Cell1CTD_human
HgenePTGS2C0205698Undifferentiated carcinoma1CTD_human
HgenePTGS2C0205699Carcinomatosis1CTD_human
HgenePTGS2C0205815Leiomyosarcoma, Epithelioid1CTD_human
HgenePTGS2C0205816Leiomyosarcoma, Myxoid1CTD_human
HgenePTGS2C0206698Cholangiocarcinoma1CTD_human
HgenePTGS2C0234533Generalized seizures1CTD_human
HgenePTGS2C0234535Clonic Seizures1CTD_human
HgenePTGS2C0235527Heart Failure, Right-Sided1CTD_human
HgenePTGS2C0242380Libman-Sacks Disease1CTD_human
HgenePTGS2C0242426Chylopericardium1CTD_human
HgenePTGS2C0259783mixed gliomas1CTD_human
HgenePTGS2C0264423Asthma, Occupational1CTD_human
HgenePTGS2C0269102Endometrioma1CTD_human
HgenePTGS2C0270823Petit mal status1CTD_human
HgenePTGS2C0270824Visual seizure1CTD_human
HgenePTGS2C0270844Tonic Seizures1CTD_human
HgenePTGS2C0270846Epileptic drop attack1CTD_human
HgenePTGS2C0271148Secondary Open Angle Glaucoma1CTD_human
HgenePTGS2C0271527Cryptogenic sexual precocity1CTD_human
HgenePTGS2C0279530Malignant Bone Neoplasm1CTD_human
HgenePTGS2C0279628Adenocarcinoma Of Esophagus1CTD_human
HgenePTGS2C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgenePTGS2C0282126Depression, Neurotic1CTD_human
HgenePTGS2C0311335Grand Mal Status Epilepticus1CTD_human
HgenePTGS2C0333233Active Hyperemia1CTD_human
HgenePTGS2C0339143Thyroid associated opthalmopathies1CTD_human
HgenePTGS2C0339573Glaucoma, Primary Open Angle1CTD_human
HgenePTGS2C0342543Central Precocious Puberty1CTD_human
HgenePTGS2C0345905Intrahepatic Cholangiocarcinoma1CTD_human
HgenePTGS2C0376323Congestive Ophthalmopathy1CTD_human
HgenePTGS2C0393734Complex Partial Status Epilepticus1CTD_human
HgenePTGS2C0422850Seizures, Somatosensory1CTD_human
HgenePTGS2C0422852Seizures, Auditory1CTD_human
HgenePTGS2C0422853Olfactory seizure1CTD_human
HgenePTGS2C0422854Gustatory seizure1CTD_human
HgenePTGS2C0422855Vertiginous seizure1CTD_human
HgenePTGS2C0494475Tonic - clonic seizures1CTD_human
HgenePTGS2C0525045Mood Disorders1PSYGENET
HgenePTGS2C0549473Thyroid carcinoma1CTD_human
HgenePTGS2C0555198Malignant Glioma1CTD_human
HgenePTGS2C0600467Neurogenic Inflammation1CTD_human
HgenePTGS2C0740457Malignant neoplasm of kidney1CTD_human
HgenePTGS2C0750887Adrenal Cancer1CTD_human
HgenePTGS2C0751056Non-epileptic convulsion1CTD_human
HgenePTGS2C0751110Single Seizure1CTD_human
HgenePTGS2C0751123Atonic Absence Seizures1CTD_human
HgenePTGS2C0751494Convulsive Seizures1CTD_human
HgenePTGS2C0751495Seizures, Focal1CTD_human
HgenePTGS2C0751496Seizures, Sensory1CTD_human
HgenePTGS2C0751522Status Epilepticus, Subclinical1CTD_human
HgenePTGS2C0751523Non-Convulsive Status Epilepticus1CTD_human
HgenePTGS2C0751524Simple Partial Status Epilepticus1CTD_human
HgenePTGS2C0751956Acute Cerebrovascular Accidents1CTD_human
HgenePTGS2C0860207Drug-Induced Liver Disease1CTD_human
HgenePTGS2C0878544Cardiomyopathies1CTD_human
HgenePTGS2C1134719Invasive Ductal Breast Carcinoma1CTD_human
HgenePTGS2C1168401Squamous cell carcinoma of the head and neck1CTD_human
HgenePTGS2C1262760Hepatitis, Drug-Induced1CTD_human
HgenePTGS2C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgenePTGS2C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgenePTGS2C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgenePTGS2C1306837Papillary Renal Cell Carcinoma1CTD_human
HgenePTGS2C1504412Testotoxicosis1CTD_human
HgenePTGS2C1563709Myopathic Ophthalmopathy1CTD_human
HgenePTGS2C1563937Atherogenesis1CTD_human
HgenePTGS2C1623038Cirrhosis1CTD_human
HgenePTGS2C1855520Hyperglycemia, Postprandial1CTD_human
HgenePTGS2C1956346Coronary Artery Disease1CTD_human
HgenePTGS2C1959583Myocardial Failure1CTD_human
HgenePTGS2C1961112Heart Decompensation1CTD_human
HgenePTGS2C2713442Polyposis, Adenomatous Intestinal1CTD_human
HgenePTGS2C2713443Familial Intestinal Polyposis1CTD_human
HgenePTGS2C3495874Nonepileptic Seizures1CTD_human
HgenePTGS2C3658290Drug-Induced Acute Liver Injury1CTD_human
HgenePTGS2C3805278Extrahepatic Cholangiocarcinoma1CTD_human
HgenePTGS2C4048158Convulsions1CTD_human
HgenePTGS2C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgenePTGS2C4279912Chemically-Induced Liver Toxicity1CTD_human
HgenePTGS2C4316903Absence Seizures1CTD_human
HgenePTGS2C4317109Epileptic Seizures1CTD_human
HgenePTGS2C4317123Myoclonic Seizures1CTD_human
HgenePTGS2C4505436Generalized Absence Seizures1CTD_human