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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:REL-MAN1A2 (FusionGDB2 ID:HG5966TG10905)

Fusion Gene Summary for REL-MAN1A2

check button Fusion gene summary
Fusion gene informationFusion gene name: REL-MAN1A2
Fusion gene ID: hg5966tg10905
HgeneTgene
Gene symbol

REL

MAN1A2

Gene ID

5966

10905

Gene nameREL proto-oncogene, NF-kB subunitmannosidase alpha class 1A member 2
SynonymsC-RelMAN1B
Cytomap('REL')('MAN1A2')

2p16.1

1p12

Type of geneprotein-codingprotein-coding
Descriptionproto-oncogene c-Reloncogene REL, avian reticuloendotheliosisv-rel avian reticuloendotheliosis viral oncogene homologmannosyl-oligosaccharide 1,2-alpha-mannosidase IBalpha-1,2-mannosidase IBalpha1,2-mannosidaseprocessing alpha-1,2-mannosidase IB
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000295025, ENST00000394479, 
Fusion gene scores* DoF score5 X 6 X 4=12012 X 8 X 6=576
# samples 715
** MAII scorelog2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(15/576*10)=-1.94110631094643
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: REL [Title/Abstract] AND MAN1A2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointREL(61147777)-MAN1A2(118035769), # samples:3
Anticipated loss of major functional domain due to fusion event.REL-MAN1A2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
REL-MAN1A2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneREL

GO:0010629

negative regulation of gene expression

22065573

HgeneREL

GO:0032688

negative regulation of interferon-beta production

22065573

HgeneREL

GO:0045944

positive regulation of transcription by RNA polymerase II

1406630


check buttonFusion gene breakpoints across REL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MAN1A2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-60-2726-01ARELchr2

61147777

-MAN1A2chr1

118035769

+
ChimerDB4LUSCTCGA-60-2726-01ARELchr2

61147777

+MAN1A2chr1

118035769

+
ChimerDB4LUSCTCGA-60-2726RELchr2

61147777

+MAN1A2chr1

118035769

+


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Fusion Gene ORF analysis for REL-MAN1A2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000295025ENST00000482811RELchr2

61147777

+MAN1A2chr1

118035769

+
5CDS-intronENST00000394479ENST00000482811RELchr2

61147777

+MAN1A2chr1

118035769

+
In-frameENST00000295025ENST00000356554RELchr2

61147777

+MAN1A2chr1

118035769

+
In-frameENST00000394479ENST00000356554RELchr2

61147777

+MAN1A2chr1

118035769

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000295025RELchr261147777+ENST00000356554MAN1A2chr1118035769+808014072542164636
ENST00000394479RELchr261147777+ENST00000356554MAN1A2chr1118035769+784911761191933604

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295025ENST00000356554RELchr261147777+MAN1A2chr1118035769+0.0001783940.9998216
ENST00000394479ENST00000356554RELchr261147777+MAN1A2chr1118035769+0.000161970.999838

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Fusion Genomic Features for REL-MAN1A2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
RELchr261147777+MAN1A2chr1118035768+8.42E-060.99999154
RELchr261147777+MAN1A2chr1118035768+8.42E-060.99999154
RELchr261147777+MAN1A2chr1118035768+8.42E-060.99999154
RELchr261147777+MAN1A2chr1118035768+8.42E-060.99999154

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for REL-MAN1A2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:61147777/chr1:118035769)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRELchr2:61147777chr1:118035769ENST00000295025+10118_297362620.0DomainRHD
HgeneRELchr2:61147777chr1:118035769ENST00000295025+1011290_295362620.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMAN1A2chr2:61147777chr1:118035769ENST000003565547132_36389642.0Topological domainCytoplasmic
TgeneMAN1A2chr2:61147777chr1:118035769ENST0000035655471358_641389642.0Topological domainLumenal
TgeneMAN1A2chr2:61147777chr1:118035769ENST0000035655471337_57389642.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for REL-MAN1A2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>73447_73447_1_REL-MAN1A2_REL_chr2_61147777_ENST00000295025_MAN1A2_chr1_118035769_ENST00000356554_length(transcript)=8080nt_BP=1407nt
AGCCGCGGGAAATTCCCCTCCCGCCAGGCTGCTCGCCTCTCGGCTGGGCCAGCACTCGGCTCTCCCCGCTCCGCCCCCTGCCCCTGGCTC
CCGTACGGTGGACGGCGACGCTGGGTGACCCGGGGTGCAAGAATTCAGGGGTTGGGAAGGTGTGAGCCGCAAACCCAGCGGAGGGCGGGA
AGAAGGAGGAGGCCTCTAGGGTGGTCGGGGGACTGGGGGCCCCGCCGGCAGAGGTCCCTCGGCCTCCTGACTGACTGACTGCGGCCGCCT
CCGGCCAGGACGCTGGGAGCTGCCTGCGGGAAGGTGCGGGGAGCGGAGCCATGGCCTCCGGTGCGTATAACCCGTATATAGAGATAATTG
AACAACCCAGGCAGAGGGGAATGCGTTTTAGATACAAATGTGAAGGGCGATCAGCAGGCAGCATTCCAGGGGAGCACAGCACAGACAACA
ACCGAACATACCCTTCTATCCAGATTATGAACTATTATGGAAAAGGAAAAGTGAGAATTACATTAGTAACAAAGAATGACCCATATAAAC
CTCATCCTCATGATTTAGTTGGAAAAGACTGCAGAGACGGCTACTATGAAGCAGAATTTGGACAAGAACGCAGACCTTTGTTTTTCCAAA
ATTTGGGTATTCGATGTGTGAAGAAAAAAGAAGTAAAAGAAGCTATTATTACAAGAATAAAGGCAGGAATCAATCCATTCAATGTCCCTG
AAAAACAGCTGAATGATATTGAAGATTGTGACCTCAATGTGGTGAGACTGTGTTTTCAAGTTTTTCTCCCTGATGAACATGGTAATTTGA
CGACTGCTCTTCCTCCTGTTGTCTCGAACCCAATTTATGACAACCGTGCTCCAAATACTGCAGAATTAAGGATTTGTCGTGTAAACAAGA
ATTGTGGAAGTGTCAGAGGAGGAGATGAAATATTTCTACTTTGTGACAAAGTTCAGAAAGATGACATAGAAGTTCGTTTTGTGTTGAACG
ATTGGGAAGCAAAAGGCATCTTTTCACAAGCTGATGTACACCGTCAAGTAGCCATTGTTTTCAAAACTCCACCATATTGCAAAGCTATCA
CAGAACCCGTAACAGTAAAAATGCAGTTGCGGAGACCTTCTGACCAGGAAGTTAGTGAATCTATGGATTTTAGATATCTGCCAGATGAAA
AAGATACTTACGGCAATAAAGCAAAGAAACAAAAGACAACTCTGCTTTTCCAGAAACTGTGCCAGGATCACGTAGAAACAGGGTTTCGCC
ATGTTGACCAGGATGGTCTTGAACTCCTGACATCAGGTGATCCACCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGTTAATTTTCCTG
AGAGACCAAGACCTGGTCTCCTCGGTTCAATTGGAGAAGGAAGATACTTCAAAAAAGATCATACATCTGTCGGTGGCCTGGGAGACAGTT
TTTATGAATACTTACTGAAAGCATGGTTGATGTCAGATAAAACAGACCATGAGGCAAGAAAGATGTATGATGATGCTATTGAGGCTATAG
AAAAACATCTTATTAAGAAGTCTCGTGGAGGTCTTACCTTTATTGGAGAATGGAAGAATGGGCACTTGGAAAAAAAGATGGGGCATTTGG
CCTGCTTTGCTGGGGGAATGTTTGCACTAGGAGCAGATGGTTCCAGAGCAGATAAAGCTGGTCATTATTTAGAGCTAGGGGCAGAAATTG
CACGTACTTGTCATGAGTCATATGACAGAACTGCATTAAAGCTAGGTCCTGAATCATTCAAGTTTGATGGTGCAGTGGAGGCTGTGGCTG
TCCGGCAGGCTGAAAAGTATTATATCCTCCGTCCAGAAGTAATTGAAACCTATTGGTACCTATGGCGATTCACTCACGATCCAAGATACA
GGCAGTGGGGCTGGGAAGCAGCACTGGCCATTGAAAAGTATTGCCGAGTTAATGGTGGGTTTTCTGGAGTCAAAGATGTATATTCCTCTA
CTCCTACACATGATGATGTACAGCAGAGCTTTTTTCTTGCTGAAACATTAAAATATTTGTATCTGCTGTTCTCCGGTGATGACCTTTTAC
CTTTAGACCACTGGGTGTTTAATACAGAGGCTCACCCTCTGCCTGTGTTACATTTAGCCAACACCACACTTTCAGGTAATCCTGCTGTTC
GATGAAAGCAGTTCCAGAAGGACCATTCTCACCTGTGTTTTGTTTACATGGACCACTACAGAAATTAGTTTGAAGGGGCGGCTTTTGAAA
ACCTGGACCTCTATGTCAACATGACAGGGTGAAACTATTCCCCCTAAGACTGTTCAACTTGTAGATACATCAACTTTGAAATTATTCCAT
TTTATACCTGACCAAAACATGTTCTGATATGTGTAGGACAGAGACCTGGATGTGCTTTGATCGTTAATGAGGTGGTCACATGAGAAATGA
TACCTGTTACTACTGTATTGTTTTTAGAGTCCTGAAGTCTGGAGGCTAGACTTCCTGAAAGCAAGTCAAGAATATAGAGCACCTTGCAGG
AGTTCAAGATGGCCTTTGGAACCAATTATGTATTTGTTTCCTCCTACAGTGGAGCAGCATTCAAATCAAATATTTACATATTGCTTATCA
CTTTTTCTCCATTTTAATAATGGAATGAACTAAAATAAACAAGAACAAAAGAATAGTATAATTATATCAGTAACAAGAAGACTCAAAAAA
GAAACAGGAGTACCTATCCCTATCTGAATTTTCAAGTTCCCCATTGGATGACCAGACTGGCAACCATTTCAAATCCCAGTCTATTTCATT
GAAATTTCTTGGTTAAGTTTAATTTTCTCTGGGGGCATGATCTCACAAAGAATACTCAAGTCTTTTTCTTCTTATGGAATCATCGAAACT
GCTATTTATCATAATCACCACTTATGAGCCTGGGTTTGGGATTTTGTGCATGTAGTTCAGTCTAGTGTTGGTAGCATGACAGAAAGTGGG
GAAAATGCCGCAGTTTGTTGCCTTGAAACCTAAGAGCAATCCTTGGTTTTGTTGCTACATTATTTTTCCAGACCAACACATCTACCAAGT
AAATTTTATTCACTTTAATTTCATAATAAAGTTAGTAGAGTCACTCAACTTACAACTTTATTTATGTGGCTTGGCAAAAATCACTATAAG
GCAGCTCTAAATTTGCCTTGATAAGCTAAATAAATTACTTTTATAACTTACTAAAGCAGAACAAACAGTGAAACTTTCTAAAATATTCTA
TCTGGAATAGGGACAGGGGATCTTTTATTTATAATCTCATCAGATGAGTGAGTTGTTCACAGATATTTTATGTTTTTTTAATTTTCTCCA
AGAATATTTATAGAATTCCAAAGAATCAGAATAGTTTCAAAATAATTTTCAGTGATAAAAGAGTGTTGTAATTAATCATATTACACTAAA
ATTGGGATACATCTAAGGAACTTTATCTTACTATCAGTAGGTTTTGCATTGATATTTCTTTTTAAATAAACTACTAGTTCTTTATATTTT
GACAAAAAGAACTTAAATTTTATCAGGAACTGTAAGATAAATATCTAGTGCTTATAAATTTTCTGTCCTTAAATTTATGTGACAGTGCAA
GATACTTTTGCTCTTTTCATTTAATATAGGCATCTTCCATTGACATTAATAAAACTTAGAAACAGTATAATTAGTATAACATTTACTCTG
AATTTGAAGATTTCCTGAAACAAAGTTTGTACAAGAAGCCCACCTTGGAATTCTGAAGGCTTATTTTCTTGTTTGATAAGCTTTTCTTTT
AAACTTAGGTTTTAAGTTGGGGAAAGACTTAATTAACTAATATAGTATTTTCTAAGGTTGATCATCTTATACCACGAATCGTTAATTTTG
ACAGTTCTACTGATCCGTAAATGATAACCACTGCAAATTTTTTCAGTATAAAATTTTTCACTGCAAAAAAATTTCAGTAGAAAATAAGGA
TGCAGGGCCAGTTACAATAGTCCTTAAGAGAGTTAAATTATAGCACATGTTTTGACATTGTAATATCTTTTACTACTTGAACATTTAAAT
TTCTAAATGAGAAAGGTATATATATTACTGTAACTGTAGAAGGGAAAAGGGAAAGTATTTGGTTCTAAAAAATGTTAGCCTTCCTCGTAA
AAGTAGCACAAGCCCACTTATGAATCACTGAGAAAAAGTGAAAAACTTGAGTTGGCAAAGATGCAGAGCAGCAGTGCAGATGGCAATGAA
CTCTCTGAATTCTCTTTTACCTTATTTAGAAGAATGCAGAGTAAAGGGACCTTCTTGGTTCTGCAGGAACTTCTCAAGGGATGAGGAGAC
AGAACCCCTACTTCCAAGTGCTCTATTTGTATTACCCAGATGACTGAAGCTTAAGAGAAGGCAGGGAAGTATACAAGCAGAGCCAGTTCT
GGTACAAACAAAGAATTTGACAGGGACAATGGAAGGGTCTTCTTCACCACTCCTTACCTTCTATGTGATGGAAAGACTAGAGCTTATAAA
AGTACTTCCATTTTTTTATTCTCCTGAATACCAAAGGCAATTAAAGTCAGCTACAAATGACTTGCCAGTGTCATGTTTTATTTTTGTTAT
AGATTTTTAAATTATTTCCTTCAAGATCAATTCTTATCCCATATAATGCTTAGCTTCCAAGAATATTCTTTACTTTCTTCTGTCTTTTAC
AGCTCTTTGCATTTTGTAGACCTTAATACTCAGGTTAAATATTCATTGCATTTATAAGATCTTCTGCAAAAAGCCCAGAAATGGTCCTTT
TCAGGTGCCTCTTCAAAGAGCTGACACCTTACCTTGTGCCTTTGGCACAAATGTGCAGAATAGATACATCAGTTGGTGCATAATCGAAAA
AAATAGGAATTTTGAACACTGTTCTTCCTTCTACATTTATTTCTCTTCATTTTAGAATCACACTTTTTATGTTAAACCAGATTATTATTA
TTATTATTATTCAACCAGTATTAAGTTGTTAAAACCAAGGGAATGGGGCCCTAACCAAAAAGAAGTCTCAACTCAGAAAAATAAGTCCCC
AGTCAGGTGGTTCTTACTTTCTTGTGGGTTGCACATTTTGTATCTCTCTAACATCAGCGTATTCCTGACTTTAAGCAGGTGTTTATATGT
AAAATAAAACCTGGGTATCGAAGGGAAATGCATTCTTTTTATGGAGTATTGACCCTGATCCTCTATGATGTCATATAGAGCAACTCAGGG
CTATACTTGCTAGATTTTAACCAAGCAGTTTGAAATATTAATCATCATCCTCTCATCTTCTCCACTCTCCATTGCCAAAGTCTTTGTCAA
AACTCCAAATTTGTTGATAAAAGATTGTGTTTGCCATTCTCATTTATAATGCAGTTTCTCCTTAAGCCTGGAGTTTTTTGAATGAGTGCA
TGAGTAAATGAGAGAATGTGTGAACGAACATTTATGAAGTATCTAACATGTGCCAAGCATTGTGCCTGGCACTTTCAATCATTAGAATGT
TTTATGTGATTCCACAGCATTTTCTGTATGAGAGTAGCTCACAACATTTTAAATGTTTCCAATATGAATCGTGTTACAAAATTCTTAATT
TTATATTTCATATAAATTAAAGAGGAAAAAGAAAAGGTTTATAATATATTTTAAAACAATGTGTTACTGTATAATACAACTATAATTGTA
GTTAATAACTAAAACCTCTTGAAAATGTCAAAGAAATACTTGATTTCTGATGCAACTTTGACTAAAATATTTACTTTAGAAATAAAAACG
TTCTTATTTTGCTATATCACTTTAATTGCATAATTAAAAAGCAGTGTTTTATAGAAATGCTGGTTATTTTATATTCAAAAAGATTTTGTC
ACATAATTCATGGGTAAAACTTGCAGTTGTAAATTGTGTCTGCTCTGGTATGGGCCCTATTAATAGTCCCATGCTGTTAAATATAAAGAA
AAATATACTAAAATATTCAAAGTTCCAAATAACAGTTCCTAGTAATAGTATTTTGAGTTATTTTTCTTTAGGTTTCCTTATACTCAAATT
GGCTAGGTCCTATCTTTTCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTATATATATATATATATATATATATATATGAG
AGATATATGAGATATATGAGAGATCAAGATCTATATATGTATATAAATACAATTATACACAGATAATTTTTAATACTCTTTGTTAACAAA
CACAGTTGAAAACTGGTTTCGGCTGCACAAATAAGCAGAATATTTGAGTAACTATATATGATATGGAGATATTTTAATCCATTTATCCTG
GCTCAAGAACACTGATAAAGATGATTTTCTGTTACTTTAGCTCATTCAGATCAGGATGGACATGCTCTTTTTGATCTATAACTGTTCAGC
CAGCTTCCAGATAATATTTTAGGCTATGAGAGCTATACAGTCTCTCTTATTACTCATTTCTGCTGTTGAAGTATCGAAAACAGATAGAGA
TACTATGTAAAGAATGGGCGTAGCTATGTTCCAGGAAAACTTTATTTACAAAAGCAGATGGAGGGCTGGATTTGGTCCATGGGTCATAGT
TAGTGACCCTGATCCCAAGTTTATTTTGTGTTAGACCCTCTAACCTTTGATCTGCGTCTTTTCTGTTTTGATTTACATAATTCATTTTTA
AATCAAAAAGATGTGCGTATATATGGTTGTGTGTATCTGTATAACCTAAAGCTATAATATTTTGTTGTCTTGAAAGCAGATACACTCTTC
CTGGAGTCTGTTCAGGTTTCAGGACGATTGACTATAATGAAAGAGACAGAATAGGGTAAGGGAAGATGGGTATGCTATCAGCCATTTTCT
TTGCCTTGTCATTTAATGCCATAATTTCAGATTCTCTATGTAAAAAGAAGGTCTGTGTATTGTCAAAATAATATACTCTCCAAGTTCTCC
TGCTCATTGACCCTTGAACCAGGATTCTGGATTGCTAGAGCTGCAGAAATTCACCCACTTGGGTACTCTTAGAGCTCTACAGCAAGAATA
TGATAGAATGTCTGATCTTTGTGCTGCAGAAAGCAAACTTTTGAAGAATTCTAAGCAACAGAAAATGGGTTATGTGACTCATCTGCTATT
TGGCAGCCACTATTCCTTTTTTAGACTGCAGAACGGTACTGCCCCTGTTACCTCTAGAATAGCCTGAGTCTGAGGAGTGCAGAGAAAAGA
TATATCCAAAAGGAGAATCCCTTTCTCTTGCATAACTCTCAATCCTTTACAAGTAAGTAGCATTATTTCAGAATGTCTATATGCATCATT
TTCAACTAAAGCATACCTCATCCTTAAACTTCCACTATTTAACAGCTAATCCATTTCAAACTTGGTTTGAGCCTAGCAATTGCAGAACTC
ATAAAATTGCTTGTGAAATTACACACCATATTACTAGCATATACATTGCAGTGCTCCAATCATGCTAACAGATAATAGATTTTTCTTTAA
GAATTTTATCAAATATTTCACTATTTGGGGAAATTTTAGAGGAGGGGAAGCCTGTATTCAGGATGATAGAGGGAGCAGAGACTTACTGTC
TCTCTTCCACATTATAAATGAACTGCCTTTCCAGGTCCAACATGCTGTCAGGTTGCTTCAGCTCGGTGTGAATGTAAGTGTGGGGATCAA
ACACACACACCTATACACATACATATTAATATGCAGAGGATTTTAAATAATTGCAAATGTCTTGTGGCTGTTTTATTTCTACAAAATTCT
GTAAGATGTATACCAGAAAACATAATAAAGATAAGCTCAGTTCTTCATTGGGAAAAAATATTTTTAAAGAAAATTTAGAAGTTTTTGCTG
AATTAAAGTATCTTCAATTTTAATTACTGGATTTGGAAGTTGAAATGCCATCCTTCAATATCACTGGTCTCAAATTCATTGATAGAATTT
TTTCTTAAACTAATAAGTGGGGTAAGTATAATCTCCTAAATTGGTACCCACTGGCTGCTCCTAAACTGGTTTCCAGTCATGTCCTCCAGT

>73447_73447_1_REL-MAN1A2_REL_chr2_61147777_ENST00000295025_MAN1A2_chr1_118035769_ENST00000356554_length(amino acids)=636AA_BP=330
MTAAASGQDAGSCLREGAGSGAMASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGKVRITLVTK
NDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPD
EHGNLTTALPPVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPP
YCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVETGFRHVDQDGLELLTSGDPPTLASQSAGI
TVNFPERPRPGLLGSIGEGRYFKKDHTSVGGLGDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEK
KMGHLACFAGGMFALGADGSRADKAGHYLELGAEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFT
HDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFSGDDLLPLDHWVFNTEAHPLPVLHLANTTLS

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>73447_73447_2_REL-MAN1A2_REL_chr2_61147777_ENST00000394479_MAN1A2_chr1_118035769_ENST00000356554_length(transcript)=7849nt_BP=1176nt
CAGGGGTTGGGAAGGTGTGAGCCGCAAACCCAGCGGAGGGCGGGAAGAAGGAGGAGGCCTCTAGGGTGGTCGGGGGACTGGGGGCCCCGC
CGGCAGAGGTCCCTCGGCCTCCTGACTGACTGACTGCGGCCGCCTCCGGCCAGGACGCTGGGAGCTGCCTGCGGGAAGGTGCGGGGAGCG
GAGCCATGGCCTCCGGTGCGTATAACCCGTATATAGAGATAATTGAACAACCCAGGCAGAGGGGAATGCGTTTTAGATACAAATGTGAAG
GGCGATCAGCAGGCAGCATTCCAGGGGAGCACAGCACAGACAACAACCGAACATACCCTTCTATCCAGATTATGAACTATTATGGAAAAG
GAAAAGTGAGAATTACATTAGTAACAAAGAATGACCCATATAAACCTCATCCTCATGATTTAGTTGGAAAAGACTGCAGAGACGGCTACT
ATGAAGCAGAATTTGGACAAGAACGCAGACCTTTGTTTTTCCAAAATTTGGGTATTCGATGTGTGAAGAAAAAAGAAGTAAAAGAAGCTA
TTATTACAAGAATAAAGGCAGGAATCAATCCATTCAATGTCCCTGAAAAACAGCTGAATGATATTGAAGATTGTGACCTCAATGTGGTGA
GACTGTGTTTTCAAGTTTTTCTCCCTGATGAACATGGTAATTTGACGACTGCTCTTCCTCCTGTTGTCTCGAACCCAATTTATGACAACC
GTGCTCCAAATACTGCAGAATTAAGGATTTGTCGTGTAAACAAGAATTGTGGAAGTGTCAGAGGAGGAGATGAAATATTTCTACTTTGTG
ACAAAGTTCAGAAAGATGACATAGAAGTTCGTTTTGTGTTGAACGATTGGGAAGCAAAAGGCATCTTTTCACAAGCTGATGTACACCGTC
AAGTAGCCATTGTTTTCAAAACTCCACCATATTGCAAAGCTATCACAGAACCCGTAACAGTAAAAATGCAGTTGCGGAGACCTTCTGACC
AGGAAGTTAGTGAATCTATGGATTTTAGATATCTGCCAGATGAAAAAGATACTTACGGCAATAAAGCAAAGAAACAAAAGACAACTCTGC
TTTTCCAGAAACTGTGCCAGGATCACGTTAATTTTCCTGAGAGACCAAGACCTGGTCTCCTCGGTTCAATTGGAGAAGGAAGATACTTCA
AAAAAGATCATACATCTGTCGGTGGCCTGGGAGACAGTTTTTATGAATACTTACTGAAAGCATGGTTGATGTCAGATAAAACAGACCATG
AGGCAAGAAAGATGTATGATGATGCTATTGAGGCTATAGAAAAACATCTTATTAAGAAGTCTCGTGGAGGTCTTACCTTTATTGGAGAAT
GGAAGAATGGGCACTTGGAAAAAAAGATGGGGCATTTGGCCTGCTTTGCTGGGGGAATGTTTGCACTAGGAGCAGATGGTTCCAGAGCAG
ATAAAGCTGGTCATTATTTAGAGCTAGGGGCAGAAATTGCACGTACTTGTCATGAGTCATATGACAGAACTGCATTAAAGCTAGGTCCTG
AATCATTCAAGTTTGATGGTGCAGTGGAGGCTGTGGCTGTCCGGCAGGCTGAAAAGTATTATATCCTCCGTCCAGAAGTAATTGAAACCT
ATTGGTACCTATGGCGATTCACTCACGATCCAAGATACAGGCAGTGGGGCTGGGAAGCAGCACTGGCCATTGAAAAGTATTGCCGAGTTA
ATGGTGGGTTTTCTGGAGTCAAAGATGTATATTCCTCTACTCCTACACATGATGATGTACAGCAGAGCTTTTTTCTTGCTGAAACATTAA
AATATTTGTATCTGCTGTTCTCCGGTGATGACCTTTTACCTTTAGACCACTGGGTGTTTAATACAGAGGCTCACCCTCTGCCTGTGTTAC
ATTTAGCCAACACCACACTTTCAGGTAATCCTGCTGTTCGATGAAAGCAGTTCCAGAAGGACCATTCTCACCTGTGTTTTGTTTACATGG
ACCACTACAGAAATTAGTTTGAAGGGGCGGCTTTTGAAAACCTGGACCTCTATGTCAACATGACAGGGTGAAACTATTCCCCCTAAGACT
GTTCAACTTGTAGATACATCAACTTTGAAATTATTCCATTTTATACCTGACCAAAACATGTTCTGATATGTGTAGGACAGAGACCTGGAT
GTGCTTTGATCGTTAATGAGGTGGTCACATGAGAAATGATACCTGTTACTACTGTATTGTTTTTAGAGTCCTGAAGTCTGGAGGCTAGAC
TTCCTGAAAGCAAGTCAAGAATATAGAGCACCTTGCAGGAGTTCAAGATGGCCTTTGGAACCAATTATGTATTTGTTTCCTCCTACAGTG
GAGCAGCATTCAAATCAAATATTTACATATTGCTTATCACTTTTTCTCCATTTTAATAATGGAATGAACTAAAATAAACAAGAACAAAAG
AATAGTATAATTATATCAGTAACAAGAAGACTCAAAAAAGAAACAGGAGTACCTATCCCTATCTGAATTTTCAAGTTCCCCATTGGATGA
CCAGACTGGCAACCATTTCAAATCCCAGTCTATTTCATTGAAATTTCTTGGTTAAGTTTAATTTTCTCTGGGGGCATGATCTCACAAAGA
ATACTCAAGTCTTTTTCTTCTTATGGAATCATCGAAACTGCTATTTATCATAATCACCACTTATGAGCCTGGGTTTGGGATTTTGTGCAT
GTAGTTCAGTCTAGTGTTGGTAGCATGACAGAAAGTGGGGAAAATGCCGCAGTTTGTTGCCTTGAAACCTAAGAGCAATCCTTGGTTTTG
TTGCTACATTATTTTTCCAGACCAACACATCTACCAAGTAAATTTTATTCACTTTAATTTCATAATAAAGTTAGTAGAGTCACTCAACTT
ACAACTTTATTTATGTGGCTTGGCAAAAATCACTATAAGGCAGCTCTAAATTTGCCTTGATAAGCTAAATAAATTACTTTTATAACTTAC
TAAAGCAGAACAAACAGTGAAACTTTCTAAAATATTCTATCTGGAATAGGGACAGGGGATCTTTTATTTATAATCTCATCAGATGAGTGA
GTTGTTCACAGATATTTTATGTTTTTTTAATTTTCTCCAAGAATATTTATAGAATTCCAAAGAATCAGAATAGTTTCAAAATAATTTTCA
GTGATAAAAGAGTGTTGTAATTAATCATATTACACTAAAATTGGGATACATCTAAGGAACTTTATCTTACTATCAGTAGGTTTTGCATTG
ATATTTCTTTTTAAATAAACTACTAGTTCTTTATATTTTGACAAAAAGAACTTAAATTTTATCAGGAACTGTAAGATAAATATCTAGTGC
TTATAAATTTTCTGTCCTTAAATTTATGTGACAGTGCAAGATACTTTTGCTCTTTTCATTTAATATAGGCATCTTCCATTGACATTAATA
AAACTTAGAAACAGTATAATTAGTATAACATTTACTCTGAATTTGAAGATTTCCTGAAACAAAGTTTGTACAAGAAGCCCACCTTGGAAT
TCTGAAGGCTTATTTTCTTGTTTGATAAGCTTTTCTTTTAAACTTAGGTTTTAAGTTGGGGAAAGACTTAATTAACTAATATAGTATTTT
CTAAGGTTGATCATCTTATACCACGAATCGTTAATTTTGACAGTTCTACTGATCCGTAAATGATAACCACTGCAAATTTTTTCAGTATAA
AATTTTTCACTGCAAAAAAATTTCAGTAGAAAATAAGGATGCAGGGCCAGTTACAATAGTCCTTAAGAGAGTTAAATTATAGCACATGTT
TTGACATTGTAATATCTTTTACTACTTGAACATTTAAATTTCTAAATGAGAAAGGTATATATATTACTGTAACTGTAGAAGGGAAAAGGG
AAAGTATTTGGTTCTAAAAAATGTTAGCCTTCCTCGTAAAAGTAGCACAAGCCCACTTATGAATCACTGAGAAAAAGTGAAAAACTTGAG
TTGGCAAAGATGCAGAGCAGCAGTGCAGATGGCAATGAACTCTCTGAATTCTCTTTTACCTTATTTAGAAGAATGCAGAGTAAAGGGACC
TTCTTGGTTCTGCAGGAACTTCTCAAGGGATGAGGAGACAGAACCCCTACTTCCAAGTGCTCTATTTGTATTACCCAGATGACTGAAGCT
TAAGAGAAGGCAGGGAAGTATACAAGCAGAGCCAGTTCTGGTACAAACAAAGAATTTGACAGGGACAATGGAAGGGTCTTCTTCACCACT
CCTTACCTTCTATGTGATGGAAAGACTAGAGCTTATAAAAGTACTTCCATTTTTTTATTCTCCTGAATACCAAAGGCAATTAAAGTCAGC
TACAAATGACTTGCCAGTGTCATGTTTTATTTTTGTTATAGATTTTTAAATTATTTCCTTCAAGATCAATTCTTATCCCATATAATGCTT
AGCTTCCAAGAATATTCTTTACTTTCTTCTGTCTTTTACAGCTCTTTGCATTTTGTAGACCTTAATACTCAGGTTAAATATTCATTGCAT
TTATAAGATCTTCTGCAAAAAGCCCAGAAATGGTCCTTTTCAGGTGCCTCTTCAAAGAGCTGACACCTTACCTTGTGCCTTTGGCACAAA
TGTGCAGAATAGATACATCAGTTGGTGCATAATCGAAAAAAATAGGAATTTTGAACACTGTTCTTCCTTCTACATTTATTTCTCTTCATT
TTAGAATCACACTTTTTATGTTAAACCAGATTATTATTATTATTATTATTCAACCAGTATTAAGTTGTTAAAACCAAGGGAATGGGGCCC
TAACCAAAAAGAAGTCTCAACTCAGAAAAATAAGTCCCCAGTCAGGTGGTTCTTACTTTCTTGTGGGTTGCACATTTTGTATCTCTCTAA
CATCAGCGTATTCCTGACTTTAAGCAGGTGTTTATATGTAAAATAAAACCTGGGTATCGAAGGGAAATGCATTCTTTTTATGGAGTATTG
ACCCTGATCCTCTATGATGTCATATAGAGCAACTCAGGGCTATACTTGCTAGATTTTAACCAAGCAGTTTGAAATATTAATCATCATCCT
CTCATCTTCTCCACTCTCCATTGCCAAAGTCTTTGTCAAAACTCCAAATTTGTTGATAAAAGATTGTGTTTGCCATTCTCATTTATAATG
CAGTTTCTCCTTAAGCCTGGAGTTTTTTGAATGAGTGCATGAGTAAATGAGAGAATGTGTGAACGAACATTTATGAAGTATCTAACATGT
GCCAAGCATTGTGCCTGGCACTTTCAATCATTAGAATGTTTTATGTGATTCCACAGCATTTTCTGTATGAGAGTAGCTCACAACATTTTA
AATGTTTCCAATATGAATCGTGTTACAAAATTCTTAATTTTATATTTCATATAAATTAAAGAGGAAAAAGAAAAGGTTTATAATATATTT
TAAAACAATGTGTTACTGTATAATACAACTATAATTGTAGTTAATAACTAAAACCTCTTGAAAATGTCAAAGAAATACTTGATTTCTGAT
GCAACTTTGACTAAAATATTTACTTTAGAAATAAAAACGTTCTTATTTTGCTATATCACTTTAATTGCATAATTAAAAAGCAGTGTTTTA
TAGAAATGCTGGTTATTTTATATTCAAAAAGATTTTGTCACATAATTCATGGGTAAAACTTGCAGTTGTAAATTGTGTCTGCTCTGGTAT
GGGCCCTATTAATAGTCCCATGCTGTTAAATATAAAGAAAAATATACTAAAATATTCAAAGTTCCAAATAACAGTTCCTAGTAATAGTAT
TTTGAGTTATTTTTCTTTAGGTTTCCTTATACTCAAATTGGCTAGGTCCTATCTTTTCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTATATATATATATATATATATATATATATGAGAGATATATGAGATATATGAGAGATCAAGATCTATATATGTATATAAATACA
ATTATACACAGATAATTTTTAATACTCTTTGTTAACAAACACAGTTGAAAACTGGTTTCGGCTGCACAAATAAGCAGAATATTTGAGTAA
CTATATATGATATGGAGATATTTTAATCCATTTATCCTGGCTCAAGAACACTGATAAAGATGATTTTCTGTTACTTTAGCTCATTCAGAT
CAGGATGGACATGCTCTTTTTGATCTATAACTGTTCAGCCAGCTTCCAGATAATATTTTAGGCTATGAGAGCTATACAGTCTCTCTTATT
ACTCATTTCTGCTGTTGAAGTATCGAAAACAGATAGAGATACTATGTAAAGAATGGGCGTAGCTATGTTCCAGGAAAACTTTATTTACAA
AAGCAGATGGAGGGCTGGATTTGGTCCATGGGTCATAGTTAGTGACCCTGATCCCAAGTTTATTTTGTGTTAGACCCTCTAACCTTTGAT
CTGCGTCTTTTCTGTTTTGATTTACATAATTCATTTTTAAATCAAAAAGATGTGCGTATATATGGTTGTGTGTATCTGTATAACCTAAAG
CTATAATATTTTGTTGTCTTGAAAGCAGATACACTCTTCCTGGAGTCTGTTCAGGTTTCAGGACGATTGACTATAATGAAAGAGACAGAA
TAGGGTAAGGGAAGATGGGTATGCTATCAGCCATTTTCTTTGCCTTGTCATTTAATGCCATAATTTCAGATTCTCTATGTAAAAAGAAGG
TCTGTGTATTGTCAAAATAATATACTCTCCAAGTTCTCCTGCTCATTGACCCTTGAACCAGGATTCTGGATTGCTAGAGCTGCAGAAATT
CACCCACTTGGGTACTCTTAGAGCTCTACAGCAAGAATATGATAGAATGTCTGATCTTTGTGCTGCAGAAAGCAAACTTTTGAAGAATTC
TAAGCAACAGAAAATGGGTTATGTGACTCATCTGCTATTTGGCAGCCACTATTCCTTTTTTAGACTGCAGAACGGTACTGCCCCTGTTAC
CTCTAGAATAGCCTGAGTCTGAGGAGTGCAGAGAAAAGATATATCCAAAAGGAGAATCCCTTTCTCTTGCATAACTCTCAATCCTTTACA
AGTAAGTAGCATTATTTCAGAATGTCTATATGCATCATTTTCAACTAAAGCATACCTCATCCTTAAACTTCCACTATTTAACAGCTAATC
CATTTCAAACTTGGTTTGAGCCTAGCAATTGCAGAACTCATAAAATTGCTTGTGAAATTACACACCATATTACTAGCATATACATTGCAG
TGCTCCAATCATGCTAACAGATAATAGATTTTTCTTTAAGAATTTTATCAAATATTTCACTATTTGGGGAAATTTTAGAGGAGGGGAAGC
CTGTATTCAGGATGATAGAGGGAGCAGAGACTTACTGTCTCTCTTCCACATTATAAATGAACTGCCTTTCCAGGTCCAACATGCTGTCAG
GTTGCTTCAGCTCGGTGTGAATGTAAGTGTGGGGATCAAACACACACACCTATACACATACATATTAATATGCAGAGGATTTTAAATAAT
TGCAAATGTCTTGTGGCTGTTTTATTTCTACAAAATTCTGTAAGATGTATACCAGAAAACATAATAAAGATAAGCTCAGTTCTTCATTGG
GAAAAAATATTTTTAAAGAAAATTTAGAAGTTTTTGCTGAATTAAAGTATCTTCAATTTTAATTACTGGATTTGGAAGTTGAAATGCCAT
CCTTCAATATCACTGGTCTCAAATTCATTGATAGAATTTTTTCTTAAACTAATAAGTGGGGTAAGTATAATCTCCTAAATTGGTACCCAC
TGGCTGCTCCTAAACTGGTTTCCAGTCATGTCCTCCAGTATGTGATTTTTATAAATTAAAGGTAATATTGTATATTAAAGTTCAAATAAA

>73447_73447_2_REL-MAN1A2_REL_chr2_61147777_ENST00000394479_MAN1A2_chr1_118035769_ENST00000356554_length(amino acids)=604AA_BP=352
MTAAASGQDAGSCLREGAGSGAMASGAYNPYIEIIEQPRQRGMRFRYKCEGRSAGSIPGEHSTDNNRTYPSIQIMNYYGKGKVRITLVTK
NDPYKPHPHDLVGKDCRDGYYEAEFGQERRPLFFQNLGIRCVKKKEVKEAIITRIKAGINPFNVPEKQLNDIEDCDLNVVRLCFQVFLPD
EHGNLTTALPPVVSNPIYDNRAPNTAELRICRVNKNCGSVRGGDEIFLLCDKVQKDDIEVRFVLNDWEAKGIFSQADVHRQVAIVFKTPP
YCKAITEPVTVKMQLRRPSDQEVSESMDFRYLPDEKDTYGNKAKKQKTTLLFQKLCQDHVNFPERPRPGLLGSIGEGRYFKKDHTSVGGL
GDSFYEYLLKAWLMSDKTDHEARKMYDDAIEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLELG
AEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFTHDPRYRQWGWEAALAIEKYCRVNGGFSGVKDV

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Fusion Gene PPI Analysis for REL-MAN1A2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for REL-MAN1A2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for REL-MAN1A2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRELC0003873Rheumatoid Arthritis3CTD_human
HgeneRELC0019829Hodgkin Disease1CGI;CTD_human
HgeneRELC0025261Memory Disorders1CTD_human
HgeneRELC0030246Pustulosis of Palms and Soles1CTD_human
HgeneRELC0033860Psoriasis1CTD_human
HgeneRELC0152266Mixed Cellularity Hodgkin Lymphoma1CTD_human
HgeneRELC0152267Hodgkin lymphoma, lymphocyte depletion1CTD_human
HgeneRELC0220597Adult Hodgkin Lymphoma1CTD_human
HgeneRELC0233794Memory impairment1CTD_human
HgeneRELC0751292Age-Related Memory Disorders1CTD_human
HgeneRELC0751293Memory Disorder, Semantic1CTD_human
HgeneRELC0751294Memory Disorder, Spatial1CTD_human
HgeneRELC0751295Memory Loss1CTD_human
HgeneRELC1266194Lymphocyte Rich Classical Hodgkin Lymphoma1CTD_human
HgeneRELC1334968Nodular Lymphocyte Predominant Hodgkin Lymphoma1CTD_human