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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:THADA-PPARG (FusionGDB2 ID:HG63892TG5468)

Fusion Gene Summary for THADA-PPARG

Fusion gene summary

Fusion gene information	Fusion gene name: THADA-PPARG
	Fusion gene ID: hg63892tg5468
		Hgene	Tgene
	Gene symbol	THADA	PPARG
	Gene ID	63892	5468
	Gene name	THADA armadillo repeat containing	peroxisome proliferator activated receptor gamma
	Synonyms	ARMC13\|GITA	CIMT1\|GLM1\|NR1C3\|PPARG1\|PPARG2\|PPARgamma
	Cytomap	('THADA')('PPARG') 2p21	3p25.2
	Type of gene	protein-coding	protein-coding
	Description	thyroid adenoma-associated proteindeath receptor-interacting proteingene inducing thyroid adenomas protein	peroxisome proliferator-activated receptor gammaPPAR-gammanuclear receptor subfamily 1 group C member 3peroxisome proliferator-activated nuclear receptor gamma variant 1
	Modification date	20200313	20200329
	UniProtAcc	.	P37231
	Ensembl transtripts involved in fusion gene	ENST00000330266, ENST00000405006, ENST00000405975, ENST00000415080, ENST00000485353, ENST00000402360, ENST00000403856, ENST00000404790,
Fusion gene scores	* DoF score	16 X 16 X 12=3072	11 X 14 X 10=1540
	# samples	18	23
	** MAII score	log2(18/3072*10)=-4.09310940439148 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(23/1540*10)=-2.74322458463789 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: THADA [Title/Abstract] AND PPARG [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	THADA(43823177)-PPARG(12361071), # samples:1 THADA(43654835)-PPARG(12365772), # samples:1 THADA(43655236)-PPARG(12361330), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	PPARG	GO:0000122	negative regulation of transcription by RNA polymerase II	12700342
Tgene	PPARG	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	18293083
Tgene	PPARG	GO:0007165	signal transduction	9568716
Tgene	PPARG	GO:0010742	macrophage derived foam cell differentiation	26504087
Tgene	PPARG	GO:0010745	negative regulation of macrophage derived foam cell differentiation	19114110
Tgene	PPARG	GO:0010871	negative regulation of receptor biosynthetic process	12700342
Tgene	PPARG	GO:0010887	negative regulation of cholesterol storage	19114110
Tgene	PPARG	GO:0010891	negative regulation of sequestering of triglyceride	12700342
Tgene	PPARG	GO:0016525	negative regulation of angiogenesis	28566713
Tgene	PPARG	GO:0030224	monocyte differentiation	9568716
Tgene	PPARG	GO:0032526	response to retinoic acid	16239304
Tgene	PPARG	GO:0042953	lipoprotein transport	9568716
Tgene	PPARG	GO:0043537	negative regulation of blood vessel endothelial cell migration	28566713
Tgene	PPARG	GO:0045713	low-density lipoprotein particle receptor biosynthetic process	9568716
Tgene	PPARG	GO:0045944	positive regulation of transcription by RNA polymerase II	9568715\|12700342\|16239304\|17611579
Tgene	PPARG	GO:0048469	cell maturation	9568716
Tgene	PPARG	GO:0048662	negative regulation of smooth muscle cell proliferation	20622039
Tgene	PPARG	GO:0051091	positive regulation of DNA-binding transcription factor activity	18293083
Tgene	PPARG	GO:0061614	pri-miRNA transcription by RNA polymerase II	28566713
Tgene	PPARG	GO:0071404	cellular response to low-density lipoprotein particle stimulus	9568716
Tgene	PPARG	GO:1904706	negative regulation of vascular smooth muscle cell proliferation	28522568

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	thyroid adenoma	AY149631	THADA	chr2	43823177		PPARG	chr3	12361071
ChiTaRS5.0	N/A	AY149630	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
ChiTaRS5.0	N/A	AY149631	THADA	chr2	43655236	-	PPARG	chr3	12361330	-

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Fusion Gene ORF analysis for THADA-PPARG

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000330266	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000330266	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405006	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000405975	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5CDS-intron	ENST00000415080	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
5UTR-intron	ENST00000485353	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000330266	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000330266	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000330266	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000402360	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000402360	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000402360	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000403856	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000403856	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000403856	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000287820	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000309576	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000397000	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000397010	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000397012	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000397015	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000397026	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000404790	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000404790	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000404790	ENST00000539812	THADA	chr2	43655236	-	PPARG	chr3	12361330	-
intron-intron	ENST00000405006	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405006	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405006	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000405975	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000405975	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000415080	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000415080	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000287820	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000287820	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000309576	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000309576	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000397000	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000397000	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000397010	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000397010	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000397012	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000397012	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000397015	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000397015	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000397026	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000397026	THADA	chr2	43654835	-	PPARG	chr3	12365772	-
intron-intron	ENST00000485353	ENST00000539812	THADA	chr2	43823177		PPARG	chr3	12361071
intron-intron	ENST00000485353	ENST00000539812	THADA	chr2	43654835	-	PPARG	chr3	12365772	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for THADA-PPARG

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

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Fusion Protein Features for THADA-PPARG

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:43823177/:12361071)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	PPARG P37231
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels (By similarity). {ECO:0000250\|UniProtKB:P37238, ECO:0000269\|PubMed:16150867, ECO:0000269\|PubMed:20829347, ECO:0000269\|PubMed:23525231, ECO:0000269\|PubMed:9065481}.; FUNCTION: (Microbial infection) Upon treatment with M.tuberculosis or its lipoprotein LpqH, phosphorylation of MAPK p38 and IL-6 production are modulated, probably via this protein. {ECO:0000269\|PubMed:25504154}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for THADA-PPARG

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for THADA-PPARG

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for THADA-PPARG

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner	Gene	UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Tgene	PPARG	P37231	DB00244	Mesalazine	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB00244	Mesalazine	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB00573	Fenoprofen		Small molecule	Approved
Tgene	PPARG	P37231	DB00573	Fenoprofen		Small molecule	Approved
Tgene	PPARG	P37231	DB00795	Sulfasalazine	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB00795	Sulfasalazine	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB01050	Ibuprofen	Activator	Small molecule	Approved
Tgene	PPARG	P37231	DB01050	Ibuprofen	Activator	Small molecule	Approved
Tgene	PPARG	P37231	DB02266	Flufenamic acid	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB02266	Flufenamic acid	Agonist	Small molecule	Approved
Tgene	PPARG	P37231	DB13873	Fenofibric acid		Small molecule	Approved
Tgene	PPARG	P37231	DB13873	Fenofibric acid		Small molecule	Approved
Tgene	PPARG	P37231	DB11672	Curcumin		Small molecule	Approved\|Experimental\|Investigational
Tgene	PPARG	P37231	DB11672	Curcumin		Small molecule	Approved\|Experimental\|Investigational
Tgene	PPARG	P37231	DB00313	Valproic acid		Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00313	Valproic acid		Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00328	Indomethacin	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00328	Indomethacin	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00412	Rosiglitazone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00412	Rosiglitazone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00731	Nateglinide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00731	Nateglinide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00845	Clofazimine	Modulator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00845	Clofazimine	Modulator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00912	Repaglinide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00912	Repaglinide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00966	Telmisartan	Partial agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00966	Telmisartan	Partial agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01014	Balsalazide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01014	Balsalazide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01067	Glipizide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01067	Glipizide	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01118	Amiodarone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01118	Amiodarone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01132	Pioglitazone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01132	Pioglitazone	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01393	Bezafibrate	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB01393	Bezafibrate	Agonist	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB03756	Doconexent	Ligand	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB03756	Doconexent	Ligand	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB08604	Triclosan		Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB08604	Triclosan		Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB09061	Cannabidiol	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB09061	Cannabidiol	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB09213	Dexibuprofen	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB09213	Dexibuprofen	Activator	Small molecule	Approved\|Investigational
Tgene	PPARG	P37231	DB00132	alpha-Linolenic acid		Small molecule	Approved\|Investigational\|Nutraceutical
Tgene	PPARG	P37231	DB00132	alpha-Linolenic acid		Small molecule	Approved\|Investigational\|Nutraceutical
Tgene	PPARG	P37231	DB04224	Oleic Acid	Ligand	Small molecule	Approved\|Investigational\|Vet_approved
Tgene	PPARG	P37231	DB04224	Oleic Acid	Ligand	Small molecule	Approved\|Investigational\|Vet_approved
Tgene	PPARG	P37231	DB00197	Troglitazone	Agonist	Small molecule	Approved\|Investigational\|Withdrawn
Tgene	PPARG	P37231	DB00197	Troglitazone	Agonist	Small molecule	Approved\|Investigational\|Withdrawn
Tgene	PPARG	P37231	DB00159	Icosapent	Agonist	Small molecule	Approved\|Nutraceutical
Tgene	PPARG	P37231	DB00159	Icosapent	Agonist	Small molecule	Approved\|Nutraceutical
Tgene	PPARG	P37231	DB11133	Omega-3 fatty acids	Ligand	Small molecule	Approved\|Nutraceutical
Tgene	PPARG	P37231	DB11133	Omega-3 fatty acids	Ligand	Small molecule	Approved\|Nutraceutical
Tgene	PPARG	P37231	DB13961	Fish oil		Biotech	Approved\|Nutraceutical
Tgene	PPARG	P37231	DB13961	Fish oil		Biotech	Approved\|Nutraceutical

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Related Diseases for THADA-PPARG

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	THADA	C0011860	Diabetes Mellitus, Non-Insulin-Dependent	1	CTD_human
Tgene		C0011860	Diabetes Mellitus, Non-Insulin-Dependent	6	CTD_human;GENOMICS_ENGLAND
Tgene		C0238463	Papillary thyroid carcinoma	4	ORPHANET
Tgene		C0002152	Alloxan Diabetes	3	CTD_human
Tgene		C0002395	Alzheimer's Disease	3	CTD_human
Tgene		C0011265	Presenile dementia	3	CTD_human
Tgene		C0011853	Diabetes Mellitus, Experimental	3	CTD_human
Tgene		C0020538	Hypertensive disease	3	CTD_human
Tgene		C0021655	Insulin Resistance	3	CTD_human
Tgene		C0022660	Kidney Failure, Acute	3	CTD_human
Tgene		C0028754	Obesity	3	CTD_human;GENOMICS_ENGLAND;UNIPROT
Tgene		C0035126	Reperfusion Injury	3	CTD_human
Tgene		C0038433	Streptozotocin Diabetes	3	CTD_human
Tgene		C0276496	Familial Alzheimer Disease (FAD)	3	CTD_human
Tgene		C0494463	Alzheimer Disease, Late Onset	3	CTD_human
Tgene		C0546126	Acute Confusional Senile Dementia	3	CTD_human
Tgene		C0750900	Alzheimer's Disease, Focal Onset	3	CTD_human
Tgene		C0750901	Alzheimer Disease, Early Onset	3	CTD_human
Tgene		C0920563	Insulin Sensitivity	3	CTD_human
Tgene		C1565662	Acute Kidney Insufficiency	3	CTD_human
Tgene		C1720861	Familial Partial Lipodystrophy, Type 3	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Tgene		C2609414	Acute kidney injury	3	CTD_human
Tgene		C0021368	Inflammation	2	CTD_human
Tgene		C0022116	Ischemia	2	CTD_human
Tgene		C0024623	Malignant neoplasm of stomach	2	CTD_human
Tgene		C0025202	melanoma	2	CTD_human
Tgene		C0030297	Pancreatic Neoplasm	2	CTD_human
Tgene		C0038356	Stomach Neoplasms	2	CTD_human
Tgene		C0346647	Malignant neoplasm of pancreas	2	CTD_human
Tgene		C1708349	Hereditary Diffuse Gastric Cancer	2	CTD_human
Tgene		C0001418	Adenocarcinoma	1	CTD_human
Tgene		C0004153	Atherosclerosis	1	CTD_human
Tgene		C0004763	Barrett Esophagus	1	CTD_human
Tgene		C0007102	Malignant tumor of colon	1	CTD_human;UNIPROT
Tgene		C0009375	Colonic Neoplasms	1	CTD_human
Tgene		C0009402	Colorectal Carcinoma	1	CTD_human
Tgene		C0009404	Colorectal Neoplasms	1	CTD_human
Tgene		C0010346	Crohn Disease	1	CTD_human
Tgene		C0011849	Diabetes Mellitus	1	CTD_human
Tgene		C0011859	Lipoatrophic Diabetes Mellitus	1	ORPHANET
Tgene		C0011881	Diabetic Nephropathy	1	CTD_human
Tgene		C0017658	Glomerulonephritis	1	CTD_human
Tgene		C0017667	Nodular glomerulosclerosis	1	CTD_human
Tgene		C0018801	Heart failure	1	CTD_human
Tgene		C0018802	Congestive heart failure	1	CTD_human
Tgene		C0023212	Left-Sided Heart Failure	1	CTD_human
Tgene		C0023645	Lichen planus follicularis	1	GENOMICS_ENGLAND
Tgene		C0023794	Lipoidosis	1	CTD_human
Tgene		C0023903	Liver neoplasms	1	CTD_human
Tgene		C0025517	Metabolic Diseases	1	CTD_human
Tgene		C0027746	Nerve Degeneration	1	CTD_human
Tgene		C0029408	Degenerative polyarthritis	1	CTD_human
Tgene		C0030246	Pustulosis of Palms and Soles	1	CTD_human
Tgene		C0030625	Passive Cutaneous Anaphylaxis	1	GENOMICS_ENGLAND
Tgene		C0033860	Psoriasis	1	CTD_human
Tgene		C0035078	Kidney Failure	1	CTD_human
Tgene		C0038525	Subarachnoid Hemorrhage	1	CTD_human
Tgene		C0040136	Thyroid Neoplasm	1	CTD_human
Tgene		C0079772	T-Cell Lymphoma	1	CTD_human
Tgene		C0085278	Antiphospholipid Syndrome	1	CTD_human
Tgene		C0085413	Polycystic Kidney, Autosomal Dominant	1	CTD_human
Tgene		C0086743	Osteoarthrosis Deformans	1	CTD_human
Tgene		C0086873	Pseudopelade	1	GENOMICS_ENGLAND
Tgene		C0151468	Thyroid Gland Follicular Adenoma	1	CTD_human
Tgene		C0156147	Crohn's disease of large bowel	1	CTD_human
Tgene		C0205641	Adenocarcinoma, Basal Cell	1	CTD_human
Tgene		C0205642	Adenocarcinoma, Oxyphilic	1	CTD_human
Tgene		C0205643	Carcinoma, Cribriform	1	CTD_human
Tgene		C0205644	Carcinoma, Granular Cell	1	CTD_human
Tgene		C0205645	Adenocarcinoma, Tubular	1	CTD_human
Tgene		C0206726	gliosarcoma	1	ORPHANET
Tgene		C0221032	Familial generalized lipodystrophy	1	ORPHANET
Tgene		C0221406	Pituitary-dependent Cushing's disease	1	CTD_human
Tgene		C0235527	Heart Failure, Right-Sided	1	CTD_human
Tgene		C0236811	Chronobiology Disorders	1	CTD_human
Tgene		C0242339	Dyslipidemias	1	CTD_human
Tgene		C0242488	Acute Lung Injury	1	CTD_human
Tgene		C0267380	Crohn's disease of the ileum	1	CTD_human
Tgene		C0270192	Perinatal Subarachnoid Hemorrhage	1	CTD_human
Tgene		C0271694	Familial partial lipodystrophy	1	CTD_human
Tgene		C0282548	Leukostasis	1	CTD_human
Tgene		C0334588	Giant Cell Glioblastoma	1	ORPHANET
Tgene		C0345904	Malignant neoplasm of liver	1	CTD_human
Tgene		C0472383	Subarachnoid Hemorrhage, Spontaneous	1	CTD_human
Tgene		C0525045	Mood Disorders	1	PSYGENET
Tgene		C0549473	Thyroid carcinoma	1	CTD_human
Tgene		C0598784	Dyslipoproteinemias	1	CTD_human
Tgene		C0678202	Regional enteritis	1	CTD_human
Tgene		C0751220	Inappropriate ACTH Secretion Syndrome	1	CTD_human
Tgene		C0751530	Subarachnoid Hemorrhage, Aneurysmal	1	CTD_human
Tgene		C0795688	Subarachnoid Hemorrhage, Intracranial	1	CTD_human
Tgene		C0813142	Circadian Rhythm Disorders	1	CTD_human
Tgene		C0887800	Psychogenic Inversion of Circadian Rhythm	1	CTD_human
Tgene		C0887850	Polycystic Kidney, Type 1 Autosomal Dominant Disease	1	CTD_human
Tgene		C0949272	IIeocolitis	1	CTD_human
Tgene		C1258085	Barrett Epithelium	1	CTD_human
Tgene		C1563937	Atherogenesis	1	CTD_human
Tgene		C1565489	Renal Insufficiency	1	CTD_human
Tgene		C1704377	Bright Disease	1	CTD_human
Tgene		C1720859	Familial Partial Lipodystrophy, Type 1	1	CTD_human
Tgene		C1720860	Familial Partial Lipodystrophy, Type 2	1	CTD_human
Tgene		C1959583	Myocardial Failure	1	CTD_human
Tgene		C1961112	Heart Decompensation	1	CTD_human
Tgene		C2239176	Liver carcinoma	1	CTD_human
Tgene		C2751306	Polycystic kidney disease, type 2	1	CTD_human
Tgene		C2931367	Thyroid cancer, follicular	1	CTD_human
Tgene		C2936846	Scarring alopecia	1	GENOMICS_ENGLAND

Fusion Gene Studies in Kim Lab

Fusion gene:THADA-PPARG (FusionGDB2 ID:HG63892TG5468)

Fusion Gene Summary for THADA-PPARG

Fusion Gene ORF analysis for THADA-PPARG

Fusion Genomic Features for THADA-PPARG

Fusion Protein Features for THADA-PPARG

Fusion Gene Sequence for THADA-PPARG

Fusion Gene PPI Analysis for THADA-PPARG

Related Drugs for THADA-PPARG

Related Diseases for THADA-PPARG

Fusion Gene Studies
in Kim Lab